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Hacettepe Egitim Dergisi最新文献

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Investigation of the Effect of Formative Peer and Instructor Feedback in Asynchronous Online Learning Environment 异步在线学习环境中同伴和教师形成性反馈的影响研究
Q4 Social Sciences Pub Date : 2022-07-02 DOI: 10.16986/huje.2022.457
Yasemin Karal, Rabia ÖZDEMİR SARIALİOĞLU
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引用次数: 0
Representation of Nature of Science in Chemistry Textbooks: Employing Reconceptualized Family Resemblance Approach as a Framework 化学教科书中科学本质的表征:以重新概念化的家族相似性方法为框架
Q4 Social Sciences Pub Date : 2022-06-30 DOI: 10.16986/huje.2022.455
Suat Çelik, F. Karataş
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引用次数: 0
The Effects of Formative Assessment Practices in Science Education on Students Metacognitive Knowledge and Regulation Skills 科学教育形成性评价实践对学生元认知知识和调控技能的影响
Q4 Social Sciences Pub Date : 2022-06-30 DOI: 10.16986/huje.2022.454
Hüsne Gedi̇kli̇, Serkan Buldur
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引用次数: 0
The Effect of POE Activities Supported by Concept Networks on Laboratory Attitudes, Anxieties and Scientific Process Skills of Pre-Service Science Teachers 概念网络支持下的POE活动对职前科学教师实验室态度、焦虑和科学过程技能的影响
Q4 Social Sciences Pub Date : 2022-06-30 DOI: 10.16986/huje.2022.453
Derviş Burak Barut, Ayşe SERT ÇIBIK
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引用次数: 0
The Effect of the Psychoeducation Program and the Family Education for the Problematic Internet Prevention 心理教育与家庭教育对网络问题预防的作用
Q4 Social Sciences Pub Date : 2022-06-30 DOI: 10.16986/huje.2022.456
Özge Canoğullari, Fulya CENKSEVEN ÖNDER
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引用次数: 0
The Relationship between Understanding the Nature of Scientific Knowledge and Reasoning and Decision Making in Socioscientific Issues 理解科学知识的本质与社会科学问题中的推理和决策之间的关系
Q4 Social Sciences Pub Date : 2022-06-30 DOI: 10.16986/huje.2022.452
E. Karakaya, Osman Serhat İrez
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引用次数: 0
Bibliometric Analysis of Educational Research in Turkey: 1981-2020 WoS Articles 土耳其教育研究的文献计量分析:1981-2020年WoS文章
Q4 Social Sciences Pub Date : 2022-06-27 DOI: 10.16986/huje.2022.451
Cemal Tosun
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引用次数: 0
Predictors of Career Adaptability and Optimism of Senior Undergraduate Students 本科高年级大学生职业适应与乐观的预测因素
Q4 Social Sciences Pub Date : 2022-06-27 DOI: 10.16986/huje.2022.448
Cennet ERDOĞMUŞ ZORVER, Fidan KORKUT OWEN, H. Suna
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引用次数: 0
Analysis of Turkish-Islamic Scientists Covered in Turkish and Azerbaijani Science Textbooks 土耳其和阿塞拜疆科学教材中土耳其伊斯兰科学家的分析
Q4 Social Sciences Pub Date : 2022-06-27 DOI: 10.16986/huje.2022.449
S. Idin
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引用次数: 0
Dendritic Domain-Specific Sampling of Long-Range Axons Shapes Feedforward and Feedback Connectivity of L5 Neurons. 长距离轴突的树突域特异性取样塑造了 L5 神经元的前馈和反馈连接性
IF 5.3 Q4 Social Sciences Pub Date : 2022-04-20 Epub Date: 2022-03-03 DOI: 10.1523/JNEUROSCI.1620-21.2022
Alessandro R Galloni, Zhiwen Ye, Ede Rancz

Feedforward and feedback pathways interact in specific dendritic domains to enable cognitive functions such as predictive processing and learning. Based on axonal projections, hierarchically lower areas are thought to form synapses primarily on dendrites in middle cortical layers, whereas higher-order areas are thought to target dendrites in layer 1 and in deep layers. However, the extent to which functional synapses form in regions of axodendritic overlap has not been extensively studied. Here, we use viral tracing in the secondary visual cortex of male mice to map brain-wide inputs to thick-tufted layer 5 pyramidal neurons. Furthermore, we provide a comprehensive map of input locations through subcellular optogenetic circuit mapping. We show that input pathways target distinct dendritic domains with far greater specificity than appears from their axonal branching, often deviating substantially from the canonical patterns. Common assumptions regarding the dendrite-level interaction of feedforward and feedback inputs may thus need revisiting.SIGNIFICANCE STATEMENT Perception and learning depend on the ability of the brain to shape neuronal representations across all processing stages. Long-range connections across different hierarchical levels enable diverse sources of contextual information, such as predictions or motivational state, to modify feedforward signals. Assumptions regarding the organization of this hierarchical connectivity have not been extensively verified. Here, we assess the synaptic connectivity of brain-wide projections onto pyramidal neurons in the visual cortex of mice. Using trans-synaptic viral tracing and subcellular optogenetic circuit mapping, we show that functional synapses do not follow the consistent connectivity rule predicted by their axonal branching patterns. These findings highlight the diversity of computational strategies operating throughout cortical networks and may aid in building better artificial networks.

前馈和反馈通路在特定树突区相互作用,从而实现预测处理和学习等认知功能。根据轴突的投射,人们认为层次较低的区域主要在皮层中层的树突上形成突触,而层次较高的区域则以第 1 层和深层的树突为目标。然而,关于功能突触在轴突重叠区域形成的程度还没有广泛的研究。在这里,我们在雄性小鼠的次级视觉皮层中使用病毒追踪技术,绘制了整个大脑对厚簇第 5 层锥体神经元的输入图。此外,我们还通过亚细胞光遗传回路映射提供了输入位置的综合图谱。我们发现,输入通路以不同的树突域为目标,其特异性远远高于轴突分支,而且往往大大偏离经典模式。因此,关于前馈和反馈输入在树突水平上相互作用的常见假设可能需要重新审视。意义声明 感知和学习取决于大脑在所有处理阶段塑造神经元表征的能力。不同层次之间的长距离连接使预测或动机状态等各种背景信息源能够改变前馈信号。有关这种分层连接组织的假设尚未得到广泛验证。在这里,我们评估了小鼠视觉皮层锥体神经元全脑投射的突触连接性。我们利用跨突触病毒追踪和亚细胞光遗传回路映射,发现功能性突触并不遵循轴突分支模式所预测的一致连接规则。这些发现凸显了在整个大脑皮层网络中运行的计算策略的多样性,可能有助于构建更好的人工网络。
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引用次数: 0
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Hacettepe Egitim Dergisi
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