首页 > 最新文献

Acta Stomatologica Naissi最新文献

英文 中文
Perioral and sublingual hematoma: Oral anticoagulation therapy complication: Case study 口周和舌下血肿:口服抗凝治疗并发症:个案研究
Q4 Dentistry Pub Date : 2015-01-01 DOI: 10.5937/asn1572514S
M. Spasić, M. Tijanić, D. Nikolić, Simona Stojanović, N. Zivkovic, J. Popović, P. Janošević, M. Trajkovic, M. Stojanovic, M. Petrović
Introduction. Anticoagulation therapy includes drugs which prevent intravascular formation and spreading of a thrombus. Heparin and dicoumarin preparation are in use. Heparin preparations are commonly used when a rapid anticoagulant effect is required, they are administered intravenously, act immediately performing the inhibition of thromboplastin activation, prothrombin to thrombin conversion, and the effect of thrombin to fibrinogen. Oral anticoagulation therapy (OAT) includes drugs - antagonists of vitamin K, which is responsible for the synthesis of prothrombin complex factors - II, VII, IX and X. They are derived from coumarin and indandione. One of the most frequently used drugs from the OAT group is warfarin. It is a competitive inhibitor of vitamin K required for the carboxylation of the residues of PK factor glutamic acid. The results of this inhibition lead to the unsuccessful formation of gama carboxyglutamic acid and the production of functionally inert coagulation proteins. The aim of this study was to show a rare but dangerous complication of an inadequate application of oral anticoagulation therapy. Case study. Patient S.S., male, aged 79, was admitted to the Oral Surgery Department, Clinic of Dentistry of the Faculty of Medicine in Nis on October 5, 2012 due to a severe general condition with massive hematoma in the facial area. Anamnestic data showed that during the previous couple of days, the patient was voluntarily taking a whole tablet of Farin instead of the prescribed dose. The patient started receiving intravenous low-molecular-weight heparin therapy (Fraxarin 0.3/12h) along with the antibiotic therapy. In the following period, the patient reported daily at the Oral Surgery Department for regular check-ups. The hematoma was absorbed and the swelling was completely gone within the next 7 to 10 days.
介绍。抗凝治疗包括预防血管内血栓形成和扩散的药物。正在使用肝素和双香豆素制剂。肝素制剂通常用于需要快速抗凝作用时,它们通过静脉注射,立即起作用,抑制凝血活素激活、凝血酶原到凝血酶的转化以及凝血酶到纤维蛋白原的作用。口服抗凝治疗(OAT)包括药物-维生素K拮抗剂,它负责合成凝血酶原复合物因子- II, VII, IX和x。它们来源于香豆素和吲哚酮。OAT组中最常用的药物之一是华法林。它是PK因子谷氨酸残基羧化所需的维生素K竞争性抑制剂。这种抑制的结果导致γ羧谷氨酸的不成功形成和功能惰性凝血蛋白的产生。本研究的目的是显示口服抗凝治疗应用不充分的一种罕见但危险的并发症。案例研究。患者s.s.,男,79岁,于2012年10月5日因面部大量血肿的严重全身情况入住尼斯医学院牙科诊所口腔外科。记忆数据显示,在过去的几天里,患者自愿服用了整片的Farin,而不是处方剂量。在抗生素治疗的同时,患者开始静脉注射低分子肝素(Fraxarin 0.3/12h)。在接下来的一段时间里,患者每天到口腔外科定期检查。在接下来的7到10天内,血肿被吸收,肿胀完全消失。
{"title":"Perioral and sublingual hematoma: Oral anticoagulation therapy complication: Case study","authors":"M. Spasić, M. Tijanić, D. Nikolić, Simona Stojanović, N. Zivkovic, J. Popović, P. Janošević, M. Trajkovic, M. Stojanovic, M. Petrović","doi":"10.5937/asn1572514S","DOIUrl":"https://doi.org/10.5937/asn1572514S","url":null,"abstract":"Introduction. Anticoagulation therapy includes drugs which prevent intravascular formation and spreading of a thrombus. Heparin and dicoumarin preparation are in use. Heparin preparations are commonly used when a rapid anticoagulant effect is required, they are administered intravenously, act immediately performing the inhibition of thromboplastin activation, prothrombin to thrombin conversion, and the effect of thrombin to fibrinogen. Oral anticoagulation therapy (OAT) includes drugs - antagonists of vitamin K, which is responsible for the synthesis of prothrombin complex factors - II, VII, IX and X. They are derived from coumarin and indandione. One of the most frequently used drugs from the OAT group is warfarin. It is a competitive inhibitor of vitamin K required for the carboxylation of the residues of PK factor glutamic acid. The results of this inhibition lead to the unsuccessful formation of gama carboxyglutamic acid and the production of functionally inert coagulation proteins. The aim of this study was to show a rare but dangerous complication of an inadequate application of oral anticoagulation therapy. Case study. Patient S.S., male, aged 79, was admitted to the Oral Surgery Department, Clinic of Dentistry of the Faculty of Medicine in Nis on October 5, 2012 due to a severe general condition with massive hematoma in the facial area. Anamnestic data showed that during the previous couple of days, the patient was voluntarily taking a whole tablet of Farin instead of the prescribed dose. The patient started receiving intravenous low-molecular-weight heparin therapy (Fraxarin 0.3/12h) along with the antibiotic therapy. In the following period, the patient reported daily at the Oral Surgery Department for regular check-ups. The hematoma was absorbed and the swelling was completely gone within the next 7 to 10 days.","PeriodicalId":39229,"journal":{"name":"Acta Stomatologica Naissi","volume":"31 1","pages":"1514-1523"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71200458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanotechnology in dentistry: Current state and future perspectives 纳米技术在牙科:现状和未来的展望
Q4 Dentistry Pub Date : 2015-01-01 DOI: 10.5937/ASN1572538G
N. Gligorijević, M. Kostić
Nanotechnology is a science that deals with the research and development of materials and devices at the atomic or molecular level. In the near future, almost every aspect of human life will be influenced by nanotechnologies. With the advancement in the technology, it is also getting incorporated in various medical diagnostic and treatment fields, including dentistry (nanodentistry). Researchers in the field of dentistry have explored the potential of nanoparticles in the existing therapeutic modalities with moderate success. The key implementations in the field of dentistry includes new diagnostic systems, local drug delivery agents, restorative materials, regenerative materials, bone and tissue graft materials and implant surface modifications. This review provides detailed insights into the current nanotechnology development in the field of dentistry, and discusses potential future uses of nanotechnology.
纳米技术是一门在原子或分子水平上研究和开发材料和设备的科学。在不久的将来,人类生活的几乎每个方面都将受到纳米技术的影响。随着技术的进步,它也被纳入各种医疗诊断和治疗领域,包括牙科(纳米牙科)。牙科领域的研究人员已经探索了纳米颗粒在现有治疗方式中的潜力,并取得了一定的成功。在牙科领域的关键实现包括新的诊断系统、局部药物递送剂、修复材料、再生材料、骨和组织移植材料以及种植体表面修饰。本文综述了目前纳米技术在牙科领域的发展,并讨论了纳米技术的潜在应用前景。
{"title":"Nanotechnology in dentistry: Current state and future perspectives","authors":"N. Gligorijević, M. Kostić","doi":"10.5937/ASN1572538G","DOIUrl":"https://doi.org/10.5937/ASN1572538G","url":null,"abstract":"Nanotechnology is a science that deals with the research and development of materials and devices at the atomic or molecular level. In the near future, almost every aspect of human life will be influenced by nanotechnologies. With the advancement in the technology, it is also getting incorporated in various medical diagnostic and treatment fields, including dentistry (nanodentistry). Researchers in the field of dentistry have explored the potential of nanoparticles in the existing therapeutic modalities with moderate success. The key implementations in the field of dentistry includes new diagnostic systems, local drug delivery agents, restorative materials, regenerative materials, bone and tissue graft materials and implant surface modifications. This review provides detailed insights into the current nanotechnology development in the field of dentistry, and discusses potential future uses of nanotechnology.","PeriodicalId":39229,"journal":{"name":"Acta Stomatologica Naissi","volume":"31 1","pages":"1538-1545"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71201038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Minimally invasive technique in the treatment of hypodontia of the upper lateral incisors: Case report 微创技术治疗上侧切牙下颌缺损1例
Q4 Dentistry Pub Date : 2015-01-01 DOI: 10.5937/ASNL571455M
M. Milosavljevic, Dušan Moravčić, Z. Ajduković, G. Filipović, T. Kanjevac
Hypodontia of the upper lateral incisor, according to its frequency, is the second most frequent one, coming after hypodontia of the second lower premolar (excluding third molars). This developmental anomaly can represent a functional and an aesthetic problem. There is a large number of modes in the treatment of hypodontia of the maxillary lateral incisor. The objective of this study is to present a minimally invasive technique of constructing direct composite veneers in the treatment of hypodontia of the upper lateral incisor, and control results after three years.
上侧切牙的下颌缺损,根据其发生频率,是第二常见的下颌缺损,仅次于第二下前磨牙(不包括第三磨牙)。这种发育异常可以代表一个功能和美学问题。上颌侧切牙下颌缺损的治疗方式多种多样。本研究的目的是提出一种微创技术构建直接复合贴面治疗上侧切牙下颌缺损,并在三年后控制结果。
{"title":"Minimally invasive technique in the treatment of hypodontia of the upper lateral incisors: Case report","authors":"M. Milosavljevic, Dušan Moravčić, Z. Ajduković, G. Filipović, T. Kanjevac","doi":"10.5937/ASNL571455M","DOIUrl":"https://doi.org/10.5937/ASNL571455M","url":null,"abstract":"Hypodontia of the upper lateral incisor, according to its frequency, is the second most frequent one, coming after hypodontia of the second lower premolar (excluding third molars). This developmental anomaly can represent a functional and an aesthetic problem. There is a large number of modes in the treatment of hypodontia of the maxillary lateral incisor. The objective of this study is to present a minimally invasive technique of constructing direct composite veneers in the treatment of hypodontia of the upper lateral incisor, and control results after three years.","PeriodicalId":39229,"journal":{"name":"Acta Stomatologica Naissi","volume":"31 1","pages":"1455-1462"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71202539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low power laser efficacy in the therapy of periodontitis 低功率激光治疗牙周炎的疗效观察
Q4 Dentistry Pub Date : 2015-01-01 DOI: 10.5937/ASN1572504O
R. Obradović, L. Kesic, A. Pejčić, Marija Igić, Marija Bojović, M. Petrović
Background. Periodontitis is an inflammatory disease of periodontal tissues and is one of the most widespread diseases. It represents a huge problem with increasing importance. Modern therapy of periodontitis includes the classic treatment methods, surgery and the latest laser technology. Particularly important is that low level laser therapy is completely painless, non-invasive and without harmful effect. The aim of the study was to investigate the efficacy of low level laser therapy as an adjunct to the basic treatment of periodontitis. Material and Method. The study was conducted on 50 patients with periodontitis and clinical symptoms of gingival inflammation. During the first visit, periodontal indices were measured: plaque index (PI), gingival index (GI) periodontal Ramford index (PDI); dental plaque and tartar were removed and periodontal pockets were treated. Consequently, the right side of the jaws (group A) was treated with GaAlAs laser (Mils 94, 670 nm, 5 mW, 14 min). Laser therapy was left out on the left side the jaw of each patient (group B), in order to compare the effect of treatment with and without laser. After the first, third and fifth treatment, GI and PI were measured, and one month after finished therapy GI, Pi and PDI were measured again. Results. Comparing the mean values of indices in relation to the value before the therapy, the reduction was observed and was more pronounced on the lased side of the jaws. Comparing the mean indices values between groups, lower values were noticed on the lased compared to the non-lased side. Conclusion. Low-power lasers are effective in the elimination of gingival inflammation and improvement of periodontal health. They can be recommended as an adjunct to the basic periodontal therapy.
背景。牙周炎是牙周组织的炎症性疾病,是最普遍的疾病之一。这是一个日益重要的大问题。牙周炎的现代治疗包括经典的治疗方法、手术和最新的激光技术。特别重要的是,低水平激光治疗是完全无痛,非侵入性和无有害影响。本研究的目的是探讨低水平激光治疗作为牙周炎基础治疗的辅助治疗效果。材料和方法。该研究对50例有牙周炎和牙龈炎症临床症状的患者进行了研究。首次访视时测量牙周指标:菌斑指数(PI)、牙龈指数(GI)、牙周Ramford指数(PDI);清除牙菌斑和牙垢,治疗牙周袋。因此,用GaAlAs激光(mls 94, 670 nm, 5 mW, 14 min)治疗右侧颌骨(A组)。每例患者左侧下颚均不进行激光治疗(B组),比较激光治疗与不进行激光治疗的效果。第1、3、5次治疗后测量GI、PI,治疗结束1个月后再次测量GI、PI、PDI。结果。将指数的平均值与治疗前的值进行比较,观察到下颌激光侧的减少更为明显。比较两组间的平均指数值,有激光的一侧比无激光的一侧值更低。结论。低功率激光对消除牙龈炎症和改善牙周健康是有效的。他们可以被推荐作为基本牙周治疗的辅助手段。
{"title":"Low power laser efficacy in the therapy of periodontitis","authors":"R. Obradović, L. Kesic, A. Pejčić, Marija Igić, Marija Bojović, M. Petrović","doi":"10.5937/ASN1572504O","DOIUrl":"https://doi.org/10.5937/ASN1572504O","url":null,"abstract":"Background. Periodontitis is an inflammatory disease of periodontal tissues and is one of the most widespread diseases. It represents a huge problem with increasing importance. Modern therapy of periodontitis includes the classic treatment methods, surgery and the latest laser technology. Particularly important is that low level laser therapy is completely painless, non-invasive and without harmful effect. The aim of the study was to investigate the efficacy of low level laser therapy as an adjunct to the basic treatment of periodontitis. Material and Method. The study was conducted on 50 patients with periodontitis and clinical symptoms of gingival inflammation. During the first visit, periodontal indices were measured: plaque index (PI), gingival index (GI) periodontal Ramford index (PDI); dental plaque and tartar were removed and periodontal pockets were treated. Consequently, the right side of the jaws (group A) was treated with GaAlAs laser (Mils 94, 670 nm, 5 mW, 14 min). Laser therapy was left out on the left side the jaw of each patient (group B), in order to compare the effect of treatment with and without laser. After the first, third and fifth treatment, GI and PI were measured, and one month after finished therapy GI, Pi and PDI were measured again. Results. Comparing the mean values of indices in relation to the value before the therapy, the reduction was observed and was more pronounced on the lased side of the jaws. Comparing the mean indices values between groups, lower values were noticed on the lased compared to the non-lased side. Conclusion. Low-power lasers are effective in the elimination of gingival inflammation and improvement of periodontal health. They can be recommended as an adjunct to the basic periodontal therapy.","PeriodicalId":39229,"journal":{"name":"Acta Stomatologica Naissi","volume":"31 1","pages":"1504-1513"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71200821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Preparation of patients with hemophilia A for oral surgery A型血友病患者口腔手术准备
Q4 Dentistry Pub Date : 2015-01-01 DOI: 10.5937/asn1571486T
I. Tijanić, M. Vučić, L. Mačukanović-Golubović, G. Marjanovic, N. Burić, M. Tijanić
Hemophilia A is an inherited disease characterized by deficiency of coagulation factor VIII and bleeding tendency. It is transmitted through the X chromosome. Hemophilia A is characterized by excessive bleeding in various tissues of the body, including soft tissue hematomas and hemarthrosis. In formulating the diagnosis of hemophilia A, in addition to a well-taken medical history and physical examination, laboratory tests should also be carried out and analyzed. Tooth extraction is the most common surgical procedures in patients with hemophilia. Hematological preparation implies the application of a concentrated factor VIH for one to two days prior to the intervention to achieve a desired level of factor VIII needed for the operation. In tooth extraction, this level has to be 50% before and after the tooth extraction for 5 days, with the application of antifibrinolytic agents. In oral surgical interventions the desired level of factor VIII is 50-80% preoperatively, 30-80% for 5 days after surgery, and 30% up to 14 days, also with the use of antifibrinolytic therapy. Patients with hemophilia and inhibitors are prepared for intervention through the application of recombinant FVIIa at the dose of 120mcg/kg, repeated every 2 hours for the period of 7-10 days after the intervention. It is necessary to apply antifibrinolytic agents and local hemostatic measures. Measures of local hemostasis are unavoidable in the case of oral surgical interventions in patients with hemophilia A. Implementation of these procedures in oral surgery has the role of minimizing the possibility of intra- and postoperative bleeding in patients with hemophilia A. For this purpose, the following are mostly used: absorbable suture thread, preparations of collagen, oxycellulose, gelatin, fibrin glue, with topical application of tranexamic or epsilon aminocaproic acid. Conclusion: Close cooperation between hematologists and oral surgeons is essential in order to minimize unwanted complications in patients with hemophilia A.
A型血友病是一种以凝血因子VIII缺乏和出血倾向为特征的遗传性疾病。它通过X染色体传播。A型血友病的特点是身体各组织大量出血,包括软组织血肿和血肿。在确定A型血友病的诊断时,除了详细的病史和体格检查外,还应进行实验室检查和分析。拔牙是血友病患者最常见的外科手术。血液学准备意味着在干预前一到两天应用浓缩的VIH因子,以达到手术所需的VIII因子水平。在拔牙时,在拔牙前后5天,使用抗纤溶药物,这个水平必须是50%。在口腔手术干预中,术前所需的因子VIII水平为50-80%,术后5天内为30-80%,14天内为30%,同时使用抗纤溶治疗。血友病患者和抑制剂通过应用重组FVIIa进行干预准备,剂量为120mcg/kg,干预后每2小时重复一次,7-10天。有必要应用抗纤溶药物和局部止血措施。在血友病a患者进行口腔手术干预时,局部止血措施是不可避免的。在口腔手术中实施这些措施可以最大限度地减少血友病a患者术中和术后出血的可能性。为此,主要采用以下方法:可吸收缝线,胶原蛋白、氧纤维素、明胶、纤维蛋白胶的制备,外用氨甲环或依普西隆氨基己酸。结论:血液科医生和口腔外科医生的密切合作对于减少A型血友病患者不必要的并发症至关重要。
{"title":"Preparation of patients with hemophilia A for oral surgery","authors":"I. Tijanić, M. Vučić, L. Mačukanović-Golubović, G. Marjanovic, N. Burić, M. Tijanić","doi":"10.5937/asn1571486T","DOIUrl":"https://doi.org/10.5937/asn1571486T","url":null,"abstract":"Hemophilia A is an inherited disease characterized by deficiency of coagulation factor VIII and bleeding tendency. It is transmitted through the X chromosome. Hemophilia A is characterized by excessive bleeding in various tissues of the body, including soft tissue hematomas and hemarthrosis. In formulating the diagnosis of hemophilia A, in addition to a well-taken medical history and physical examination, laboratory tests should also be carried out and analyzed. Tooth extraction is the most common surgical procedures in patients with hemophilia. Hematological preparation implies the application of a concentrated factor VIH for one to two days prior to the intervention to achieve a desired level of factor VIII needed for the operation. In tooth extraction, this level has to be 50% before and after the tooth extraction for 5 days, with the application of antifibrinolytic agents. In oral surgical interventions the desired level of factor VIII is 50-80% preoperatively, 30-80% for 5 days after surgery, and 30% up to 14 days, also with the use of antifibrinolytic therapy. Patients with hemophilia and inhibitors are prepared for intervention through the application of recombinant FVIIa at the dose of 120mcg/kg, repeated every 2 hours for the period of 7-10 days after the intervention. It is necessary to apply antifibrinolytic agents and local hemostatic measures. Measures of local hemostasis are unavoidable in the case of oral surgical interventions in patients with hemophilia A. Implementation of these procedures in oral surgery has the role of minimizing the possibility of intra- and postoperative bleeding in patients with hemophilia A. For this purpose, the following are mostly used: absorbable suture thread, preparations of collagen, oxycellulose, gelatin, fibrin glue, with topical application of tranexamic or epsilon aminocaproic acid. Conclusion: Close cooperation between hematologists and oral surgeons is essential in order to minimize unwanted complications in patients with hemophilia A.","PeriodicalId":39229,"journal":{"name":"Acta Stomatologica Naissi","volume":"31 1","pages":"1486-1492"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71200795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Salivary humoral changes in oral bullous lichen planus 口腔大疱性扁平苔藓的唾液体液变化
Q4 Dentistry Pub Date : 2015-01-01 DOI: 10.5937/ASN1572493P
M. Popovska, A. Minovska, V. Radojkova-Nikolovska, Ilijana Muratovska, B. Kapusevska, P. Aleksova, S. Spasovski
Cilj: Cilj istraživanja bio je ispitivanje humoralnih mehanizama u pljuvački kod pacijenata sa buloznim lihen planusom u fazi egzacerbacije i remisije. Materijal i metod: Praćeno je devetnaest pacijenata sa oralnim buloznim lihen planusom. Pljuvačka je prikupljana u jutarnjim časovima, bez stimulacije, u količini 5-10 cm. Određivanje imunoglobulina, C3 i C4 u pljuvački vršilo se primenom tehnike „microelis“. Cirkulišući imuni kompleksi u serumu i pljuvački određivani su PEG metodom. Dobijeni rezultati upoređivani su sa kontrolnom grupom i međusobno u fazi egzacerbacije i remisije. Rezultati su statistički obrađeni Studentovim „t“ testom. Rezultati: Ispitivanja su pokazala da je količina IgA u pljuvački značajno smanjena , dok je količina IgG i IgM značajno uvećana. Vrednosti imunoglobulina A , G i M u fazi remisije značajno su povećane kod bolesnika u odnosu na kontrolnu grupu. Upoređivanjem pljuvačke u fazi egzacerbacije i remisije dobile su iste količine IgG u oba stadijumima bolesti , ali evidentno povišene vrednosti IgA i malo značajno povećanje vrednosti IgM. U kontrolnoj grupi i grupi pacijenata u fazi egzacerbacije i remisije takođe su povećane CIC vrednosti . Podaci ukazuju na visoko značajnu depresiju komponente C3 u fazi egzacerbacije, dok je u remisiji vidljivo malo značajno smanjenje. Komplement komponente C4 u fazi remisije opada u poređenju sa kontrolnom grupom. Zaključak: Postoji evidentno učešće pojedinih komponenti pljuvačke u patogenezi oralnog lihen planusa, ali konačna pozicija za prevlast humoralnih mehanizama u patogenezi buloznog lihen planusa još uvek ne postoji.
目的:本研究的目的是研究蓝舌患者在手术和缓解期随地吐痰的幽默机制。材料和方法:对9例口服保加利亚利亨血浆患者进行监测。游泳是在早上收集的,没有刺激,在5-10厘米。在随地吐痰中,C3和C4应用微乳液。通过PEG测定循环血清和随地吐痰免疫并发症。将所得结果与对照组以及运动期和缓解期的结果进行比较。学生对结果进行统计处理“测试。Rezultati:Ispitivanja su pokazala da je količina IgA u pljuvački značajno smanjena,dok je količina IgG i IgM znaÇajno uvećana。Vrednosti imunoglobilina A,G i M u fazi remisije značajno su povećane kod bolesnika u odnosu na kontrolnu grupu。IgG u oba stadijuima bolesti,ali evidentno poviIgA扫描的值和IgM的轻微显著增加。在对照组和处于切除和缓解期的患者组中,CIC值也有所增加。数据表明,在过度肥胖阶段,C3成分高度显著降低,而缓解率显著降低。与对照组相比,缓解期C4的完整成分下降。最后,血浆口腔晶状体的病原体中明显涉及随地吐痰的某些成分,但血浆bulozal晶状体病原体中幽默机制的普遍性仍没有最终的位置。
{"title":"Salivary humoral changes in oral bullous lichen planus","authors":"M. Popovska, A. Minovska, V. Radojkova-Nikolovska, Ilijana Muratovska, B. Kapusevska, P. Aleksova, S. Spasovski","doi":"10.5937/ASN1572493P","DOIUrl":"https://doi.org/10.5937/ASN1572493P","url":null,"abstract":"Cilj: Cilj istraživanja bio je ispitivanje humoralnih mehanizama u pljuvački kod pacijenata sa buloznim lihen planusom u fazi egzacerbacije i remisije. Materijal i metod: Praćeno je devetnaest pacijenata sa oralnim buloznim lihen planusom. Pljuvačka je prikupljana u jutarnjim časovima, bez stimulacije, u količini 5-10 cm. Određivanje imunoglobulina, C3 i C4 u pljuvački vršilo se primenom tehnike „microelis“. Cirkulišući imuni kompleksi u serumu i pljuvački određivani su PEG metodom. Dobijeni rezultati upoređivani su sa kontrolnom grupom i međusobno u fazi egzacerbacije i remisije. Rezultati su statistički obrađeni Studentovim „t“ testom. Rezultati: Ispitivanja su pokazala da je količina IgA u pljuvački značajno smanjena , dok je količina IgG i IgM značajno uvećana. Vrednosti imunoglobulina A , G i M u fazi remisije značajno su povećane kod bolesnika u odnosu na kontrolnu grupu. Upoređivanjem pljuvačke u fazi egzacerbacije i remisije dobile su iste količine IgG u oba stadijumima bolesti , ali evidentno povišene vrednosti IgA i malo značajno povećanje vrednosti IgM. U kontrolnoj grupi i grupi pacijenata u fazi egzacerbacije i remisije takođe su povećane CIC vrednosti . Podaci ukazuju na visoko značajnu depresiju komponente C3 u fazi egzacerbacije, dok je u remisiji vidljivo malo značajno smanjenje. Komplement komponente C4 u fazi remisije opada u poređenju sa kontrolnom grupom. Zaključak: Postoji evidentno učešće pojedinih komponenti pljuvačke u patogenezi oralnog lihen planusa, ali konačna pozicija za prevlast humoralnih mehanizama u patogenezi buloznog lihen planusa još uvek ne postoji.","PeriodicalId":39229,"journal":{"name":"Acta Stomatologica Naissi","volume":"31 1","pages":"1493-1503"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71200809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the costs of treating dry socket 干槽处理费用分析
Q4 Dentistry Pub Date : 2015-01-01 DOI: 10.5937/asnl571443M
A. Milojević, S. Janković, Nela Ž. Đonović, S. Stefanović, Viktorija Artinović, Ranko Golijanin
Background: Dry socket is a disturbance in the healing of tooth extraction, characterized by the absence of blood clot and persistence of intense pain. The aim of this study was to determine the costs of treating dry socket, as in Serbia, until now, there has been no adequate estimation of the expenses and cost structure for treating patients with dry socket. Material and Methods: The costs of treating dry socket were analyzed on the sample of 455 adults with confirmed diagnosis of dry socket. All the patients were treated at the Oral Surgery Department, Institute of Dental Medicine in Kragujevac, during 2012. Direct costs per patient, concerning the acquisition of medicines and medical supplies, as well as medical services, were recorded in accordance with the Blue Code Book of the National Health Insurance Fund. Results: Out of total 12.652 teeth extracted, 455patients (3.6%) were diagnosed with dry socket. Total direct cost for treating dry socket in 2012 was 1.298,58 ± 468.93 RSD per patient, of which 1.065,16 RSD ± 394.49 RSD (82.02%) was the total price of the service and 1. 298,58 ± 468.93 RSD (17.98%) was spent on dental supplies. Conclusion: The actual cost of treating dry socket in Serbia shows that there is a need for the implementation of the relevant preventive measures. Global economic crisis, worsens the constant lack of available resources in dental healthcare services. Dry socket, as one of the most frequent post-extraction complications, although quite harmless in terms of clinical prognosis represents substantial economic loss for Serbia.
背景:干窝是拔牙愈合过程中的一种障碍,其特征是没有血凝块和持续剧烈疼痛。本研究的目的是确定治疗干窝的费用,如在塞尔维亚,到目前为止,还没有对治疗干窝患者的费用和成本结构进行充分的估计。材料与方法:对455例确诊为干性眼窝的成年人进行治疗费用分析。所有患者均于2012年在克拉古耶瓦茨牙科医学研究所口腔外科接受治疗。每个病人购买药品和医疗用品以及医疗服务的直接费用是根据国家健康保险基金的蓝色代码手册记录的。结果:共拔牙12.652例,诊断干槽455例(3.6%)。2012年治疗干槽的总直接成本为1.298,58±468.93 RSD /例,其中总服务价格为1.065,16 RSD±394.49 RSD (82.02%);(298,58±468.93)RSD(17.98%)。结论:塞尔维亚干槽治疗的实际费用表明,有必要实施相应的预防措施。全球经济危机加剧了牙科保健服务中可用资源的持续缺乏。干槽作为拔牙后最常见的并发症之一,虽然在临床预后方面相当无害,但对塞尔维亚造成了巨大的经济损失。
{"title":"Analysis of the costs of treating dry socket","authors":"A. Milojević, S. Janković, Nela Ž. Đonović, S. Stefanović, Viktorija Artinović, Ranko Golijanin","doi":"10.5937/asnl571443M","DOIUrl":"https://doi.org/10.5937/asnl571443M","url":null,"abstract":"Background: Dry socket is a disturbance in the healing of tooth extraction, characterized by the absence of blood clot and persistence of intense pain. The aim of this study was to determine the costs of treating dry socket, as in Serbia, until now, there has been no adequate estimation of the expenses and cost structure for treating patients with dry socket. Material and Methods: The costs of treating dry socket were analyzed on the sample of 455 adults with confirmed diagnosis of dry socket. All the patients were treated at the Oral Surgery Department, Institute of Dental Medicine in Kragujevac, during 2012. Direct costs per patient, concerning the acquisition of medicines and medical supplies, as well as medical services, were recorded in accordance with the Blue Code Book of the National Health Insurance Fund. Results: Out of total 12.652 teeth extracted, 455patients (3.6%) were diagnosed with dry socket. Total direct cost for treating dry socket in 2012 was 1.298,58 ± 468.93 RSD per patient, of which 1.065,16 RSD ± 394.49 RSD (82.02%) was the total price of the service and 1. 298,58 ± 468.93 RSD (17.98%) was spent on dental supplies. Conclusion: The actual cost of treating dry socket in Serbia shows that there is a need for the implementation of the relevant preventive measures. Global economic crisis, worsens the constant lack of available resources in dental healthcare services. Dry socket, as one of the most frequent post-extraction complications, although quite harmless in terms of clinical prognosis represents substantial economic loss for Serbia.","PeriodicalId":39229,"journal":{"name":"Acta Stomatologica Naissi","volume":"31 1","pages":"1443-1454"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71202529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of estrogen on the gingival health of girls 雌激素对少女牙龈健康的影响
Q4 Dentistry Pub Date : 2014-12-01 DOI: 10.5937/ASN1470393R
V. Radojkova-Nikolovska, M. Popovska, A. Minovska, Vera Stojanovska, B. Džipunova, P. Aleksova, A. Atanasovska-Stojanovska, Ana Belazelkovska, Bruno Nikolovski
Introduction. Gingival inflammation during childhood and pubertal maturation increases remarkably. The aim of the study was to determine the values of the gingival indices among teenage girls, salivary and serum values of the dominant female sex hormone 17β estradiol and influence of estrogen hormone on gingival health. Patients and method. The study included 30 girls (aged 11 to 14 years) with diagnosed gingival inflammation and 30 girls with no gingivitis as a control group. Gingival health was evaluated through clinical examination of gingival indices. Serum and salivary concentrations of 17β estradiol were evaluated with DRG Estradiol ELISA (EIA-2693) and DRG Salivary Estradiol ELISA (SLV-4188) methods. Results. Gingival index values clearly indicate the presence of gingival inflammation. Analyses of correlative values comparing serum and salivary levels of estrogen hormone with indices of gingival status indicate a positive correlation with all index values, particularly emphasizing the impact of 17 β estradiol on gingival inflammation and gingival bleeding. Conclusion. The obtained values of the hormone concentrations in serum and saliva, in both groups, suggest their potential impact on the gingival health. This emphasizes the role of dentists in preventive and treatment modalities in patients during the period of puberty. Key words: puberty gingivitis, gingival index, estrogen hormones, gingival health
介绍。儿童期和青春期牙龈炎症明显增加。本研究的目的是测定青春期少女的牙龈指数、唾液和血清中占优势的女性性激素17β雌二醇的值以及雌激素对牙龈健康的影响。患者和方法。该研究包括30名被诊断患有牙龈炎症的女孩(11至14岁)和30名没有牙龈炎的女孩作为对照组。通过临床检查牙龈指标来评价牙龈健康状况。采用DRG estradiol ELISA (EIA-2693)和DRG唾液雌二醇ELISA (SLV-4188)检测血清和唾液中17β雌二醇的浓度。结果。牙龈指数值清楚地表明存在牙龈炎症。血清和唾液雌激素水平与牙龈状态指标的相关值分析显示,所有指标均呈正相关,特别强调17 β雌二醇对牙龈炎症和牙龈出血的影响。结论。在两组中,血清和唾液中获得的激素浓度值表明它们对牙龈健康的潜在影响。这强调了牙医在青春期患者的预防和治疗方式中的作用。关键词:青春期牙龈炎;牙龈指数;雌激素激素
{"title":"The influence of estrogen on the gingival health of girls","authors":"V. Radojkova-Nikolovska, M. Popovska, A. Minovska, Vera Stojanovska, B. Džipunova, P. Aleksova, A. Atanasovska-Stojanovska, Ana Belazelkovska, Bruno Nikolovski","doi":"10.5937/ASN1470393R","DOIUrl":"https://doi.org/10.5937/ASN1470393R","url":null,"abstract":"Introduction. Gingival inflammation during childhood and pubertal maturation increases remarkably. The aim of the study was to determine the values of the gingival indices among teenage girls, salivary and serum values of the dominant female sex hormone 17β estradiol and influence of estrogen hormone on gingival health. Patients and method. The study included 30 girls (aged 11 to 14 years) with diagnosed gingival inflammation and 30 girls with no gingivitis as a control group. Gingival health was evaluated through clinical examination of gingival indices. Serum and salivary concentrations of 17β estradiol were evaluated with DRG Estradiol ELISA (EIA-2693) and DRG Salivary Estradiol ELISA (SLV-4188) methods. Results. Gingival index values clearly indicate the presence of gingival inflammation. Analyses of correlative values comparing serum and salivary levels of estrogen hormone with indices of gingival status indicate a positive correlation with all index values, particularly emphasizing the impact of 17 β estradiol on gingival inflammation and gingival bleeding. Conclusion. The obtained values of the hormone concentrations in serum and saliva, in both groups, suggest their potential impact on the gingival health. This emphasizes the role of dentists in preventive and treatment modalities in patients during the period of puberty. \u0000Key words: puberty gingivitis, gingival index, estrogen hormones, gingival health","PeriodicalId":39229,"journal":{"name":"Acta Stomatologica Naissi","volume":"30 1","pages":"1393-1407"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71200881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examination of adherence of dental acrylic polymers in vivo 牙用丙烯酸聚合物在体内黏附性的检验
Q4 Dentistry Pub Date : 2014-01-01 DOI: 10.5937/ASN1470383K
M. Kostić, N. Krunić, S. Najman, J. Rajković, M. Igić, Milica Petrović, P. Janošević
{"title":"Examination of adherence of dental acrylic polymers in vivo","authors":"M. Kostić, N. Krunić, S. Najman, J. Rajković, M. Igić, Milica Petrović, P. Janošević","doi":"10.5937/ASN1470383K","DOIUrl":"https://doi.org/10.5937/ASN1470383K","url":null,"abstract":"","PeriodicalId":39229,"journal":{"name":"Acta Stomatologica Naissi","volume":"30 1","pages":"1383-1392"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71200868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The use of medicinal preparations for preprosthetic and prosthetic purposes 用于假体前和假体目的的药物制剂
Q4 Dentistry Pub Date : 2014-01-01 DOI: 10.5937/asn1470420a
Z. Ajduković, R. Obradović, G. Filipović, N. Djordjević, Dragana Kenic-Marinkovic, N. Petrović, M. Kovačević
1 UNIVERSITY OF NIŠ, FACULTY OF MEDICINE, CLINIC OF DENTISTRY, DEPARTMENT OF PROSTHODONTICS 2 UNIVERSITY OF NIŠ, FACULTY OF MEDICINE, CLINIC OF DENTISTRY, DEPARTMENT OF ORAL MEDICINE AND PERIODONTOLOGY UNIVERSITY OF NIŠ, FACULTY OF MEDICINE, CLINIC OF DENTISTRY, DEPARTMENT OF ORTHODONTICS, 4 UNIVERSITY OF PRIŠTINA, FACULTY OF MEDICINE TEMPORARILY SEATED IN KOSOVSKA MITROVICA, CLINIC OF DENTISTRY, DEPARTMENT OF PROSTHODONTICS 5 PRIVATE DENTAL PRACTICE "KALODENT" NIŠ
1 . niŠ大学医学院,牙科诊所,口腔医学和牙周病学系2 . niŠ大学医学院,牙科诊所,口腔医学和牙周病学系4 . priŠtina大学,临时设在科索沃米特罗维察的医学院,牙科诊所,口腔医学,正畸科5 .私人牙科诊所“kalodent”niŠ
{"title":"The use of medicinal preparations for preprosthetic and prosthetic purposes","authors":"Z. Ajduković, R. Obradović, G. Filipović, N. Djordjević, Dragana Kenic-Marinkovic, N. Petrović, M. Kovačević","doi":"10.5937/asn1470420a","DOIUrl":"https://doi.org/10.5937/asn1470420a","url":null,"abstract":"1 UNIVERSITY OF NIŠ, FACULTY OF MEDICINE, CLINIC OF DENTISTRY, DEPARTMENT OF PROSTHODONTICS 2 UNIVERSITY OF NIŠ, FACULTY OF MEDICINE, CLINIC OF DENTISTRY, DEPARTMENT OF ORAL MEDICINE AND PERIODONTOLOGY UNIVERSITY OF NIŠ, FACULTY OF MEDICINE, CLINIC OF DENTISTRY, DEPARTMENT OF ORTHODONTICS, 4 UNIVERSITY OF PRIŠTINA, FACULTY OF MEDICINE TEMPORARILY SEATED IN KOSOVSKA MITROVICA, CLINIC OF DENTISTRY, DEPARTMENT OF PROSTHODONTICS 5 PRIVATE DENTAL PRACTICE \"KALODENT\" NIŠ","PeriodicalId":39229,"journal":{"name":"Acta Stomatologica Naissi","volume":"30 1","pages":"1420-1431"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71200741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Acta Stomatologica Naissi
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1