Central nervous system germ cell tumor is a rare intracranial tumor lesion, accounting for 2% to 3% of all pediatric tumors. Due to its high sensitivity to radiotherapy and chemotherapy, early and accurate diagnosis and timely treatment are crucial for patient prognosis. The vast majority of patients can achieve clinical cure without surgery. Intracranial germ cell tumors are more common in the pineal region, suprasellar region, basal ganglia region, and other areas, and have certain characteristics in terms of age, gender, clinical manifestations, and imaging manifestations. This article summarizes the clinical and imaging features of intracranial germ cell tumors in order to further enhance the understanding of the disease among physicians.
{"title":"Diagnostic imaging of intracranial germinoma","authors":"Rui Li, X. Lou","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.01.020","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.01.020","url":null,"abstract":"中枢神经系统生殖细胞瘤是一种少见的颅内肿瘤性病变，占所有儿童肿瘤的2%~3%，由于其对放疗和化疗高度敏感，早期准确诊断并及时治疗对患者的预后至关重要，绝大多数患者无需手术即可达到临床治愈的效果。颅内生殖细胞瘤好发于松果体区、鞍上、基底节区等部位，其发病年龄、性别、临床表现及影像学表现等方面各有一定的特点。本文对颅内生殖细胞瘤的临床及影像学特征进行归纳总结，以期进一步提高广大医师对该病的认识。","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42107869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Seize the opportunity, meet the challenge, create a new situation about journal","authors":"Linlin Zhang, Zhengyu Jin","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.01.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.01.001","url":null,"abstract":"2019年《中华放射学杂志》在全体编委、审稿专家、读者、作者和编辑部的共同努力下，取得了优异的成绩。但是杂志发展过程中还面临很多困难和挑战，目前国家高度重视我们科技期刊的发展，为国内期刊的发展创造了良好的机遇。作为国内期刊从业者，应把握机遇，迎接挑战，努力开创杂志工作的新局面。","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46564840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-10DOI: 10.3760/CMA.J.ISSN.1005-1201.2020.01.003
Xiaoni Wang, Yu Sun, Guanqun Chen, Can Sheng, Xuan-yu Li, Yuxia Li, Wenying Du, Xiaoqi Wang, Mingrui Xia, Ying Han
Objective To explore the effects of ApoE epsilon4 (ApoE-e4) alleles on cognitive function and resting-state functional MRI (rs-fMRI) in patients with amnestic mild cognitive impairment(aMCI) based on a prospective cohort study. Methods An average of 20 months of prospective observations were conducted on 16 ApoE-e4-carriers and 24 non-carriers of aMCI. Neuropsychological assessments and rs-fMRI data were collected at both baseline and follow-up. All participants were assessed by a battery of neuropsychological tests and underwent rs-fMRI. Two core regions of the default mode network (DMN), the left posterior cingulate cortex (PCC) and the medial prefrontal cortex (mPFC), were selected as seeds to calculate the functional connectivity. Two-way repeated measures analysis of variance was used to assess the effects of ApoE genotype(e4-carriers, none4-carriers), interval and the interaction between these two factors for functional connectivity extracted from changed region found by t-test.Conversion rates of dementia were compared between ApoE-e4-carriers and none4-carriers at follow-up using Chi-square test. For the comparison of functional connectivity and clinical data between ApoE-e4-carriers and nonse4-carriers in baseline and follow-up, the normal distribution test was carried out first. If the normal distribution was fitted, the two-sample t test was used, otherwise, the Mann-Whitney rank sum test was used. Finally, the general linear model was used to assess the relationships between alterations in functional connectivity and in neuropsychological assessments as well as the interaction effect. Results (1)Significant decline in memory domains were found in ApoE-e4-carriers as compared to non-carriers at both baseline and follow-up. The ApoE-e4-carriers (14/16) presented a higher conversation rate than non-carriers(13/24, χ2=4.862, P=0.027) at follow-up. (2)Functional imaging analysis revealed that ApoE-e4-carriers exhibited significantly higher functional connectivity between the left PCC and the left angular (ApoE-e4-carriers: 0.23±0.11, non-carriers: -0.03±0.13, t=4.800, cluster size: 1 944 mm3, P=0.004), and between the left mPFC and the left angular (ApoE-e4-carriers: 0.33±0.21, non-carriers: 0.08±0.18, t=5.040, cluster size:1 836 mm3, P=0.006) as compared to non-carriers at follow-up. We detected significant effect for the interaction interval by ApoE-e4 on functional connectivity between the left angular and the left PCC (F=10.833, P=0.002)as well as the left mPFC (F=7.280, P=0.010). (3)The alteration of functional connectivity value between the left mPFC and the left angular in ApoE-e4-carriers was positively correlated with the changes ofimmediate memory (r=0.692, P=0.018). The correlation was not statistically significant in ApoE-e4-noncarriers (r=-0.198, P=0.417) and the integration effect was significant (F=8.632, P=0.006). Conclusions The ApoE-e4 actually accelerates the deterioration of cognitive function in aMCI
{"title":"The effects of ApoE epsilon4 alleles on cognitive function and resting-state functional MRI in patients with amnestic mild cognitive impairment: a prospective cohort study","authors":"Xiaoni Wang, Yu Sun, Guanqun Chen, Can Sheng, Xuan-yu Li, Yuxia Li, Wenying Du, Xiaoqi Wang, Mingrui Xia, Ying Han","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.01.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.01.003","url":null,"abstract":"Objective \u0000To explore the effects of ApoE epsilon4 (ApoE-e4) alleles on cognitive function and resting-state functional MRI (rs-fMRI) in patients with amnestic mild cognitive impairment(aMCI) based on a prospective cohort study. \u0000 \u0000 \u0000Methods \u0000An average of 20 months of prospective observations were conducted on 16 ApoE-e4-carriers and 24 non-carriers of aMCI. Neuropsychological assessments and rs-fMRI data were collected at both baseline and follow-up. All participants were assessed by a battery of neuropsychological tests and underwent rs-fMRI. Two core regions of the default mode network (DMN), the left posterior cingulate cortex (PCC) and the medial prefrontal cortex (mPFC), were selected as seeds to calculate the functional connectivity. Two-way repeated measures analysis of variance was used to assess the effects of ApoE genotype(e4-carriers, none4-carriers), interval and the interaction between these two factors for functional connectivity extracted from changed region found by t-test.Conversion rates of dementia were compared between ApoE-e4-carriers and none4-carriers at follow-up using Chi-square test. For the comparison of functional connectivity and clinical data between ApoE-e4-carriers and nonse4-carriers in baseline and follow-up, the normal distribution test was carried out first. If the normal distribution was fitted, the two-sample t test was used, otherwise, the Mann-Whitney rank sum test was used. Finally, the general linear model was used to assess the relationships between alterations in functional connectivity and in neuropsychological assessments as well as the interaction effect. \u0000 \u0000 \u0000Results \u0000(1)Significant decline in memory domains were found in ApoE-e4-carriers as compared to non-carriers at both baseline and follow-up. The ApoE-e4-carriers (14/16) presented a higher conversation rate than non-carriers(13/24, χ2=4.862, P=0.027) at follow-up. (2)Functional imaging analysis revealed that ApoE-e4-carriers exhibited significantly higher functional connectivity between the left PCC and the left angular (ApoE-e4-carriers: 0.23±0.11, non-carriers: -0.03±0.13, t=4.800, cluster size: 1 944 mm3, P=0.004), and between the left mPFC and the left angular (ApoE-e4-carriers: 0.33±0.21, non-carriers: 0.08±0.18, t=5.040, cluster size:1 836 mm3, P=0.006) as compared to non-carriers at follow-up. We detected significant effect for the interaction interval by ApoE-e4 on functional connectivity between the left angular and the left PCC (F=10.833, P=0.002)as well as the left mPFC (F=7.280, P=0.010). (3)The alteration of functional connectivity value between the left mPFC and the left angular in ApoE-e4-carriers was positively correlated with the changes ofimmediate memory (r=0.692, P=0.018). The correlation was not statistically significant in ApoE-e4-noncarriers (r=-0.198, P=0.417) and the integration effect was significant (F=8.632, P=0.006). \u0000 \u0000 \u0000Conclusions \u0000The ApoE-e4 actually accelerates the deterioration of cognitive function in aMCI","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47990348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Inflammatory bowel disease (IBD) includes Crohn's disease and ulcerative colitis. The brain gut axis can play an important role in the occurrence and development of IBD through psychological, neural, endocrine, and immune regulation. Observing and studying the brain structure and functional abnormalities of IBD patients through MRI, especially the observation of brain functional abnormalities, is conducive to a deeper understanding of the pathogenesis of IBD and finding new treatment methods from the neural perspective that may effectively alleviate intestinal inflammation or alleviate abdominal pain symptoms.
{"title":"Progress of brain functional MRI in inflammatory bowel disease","authors":"Lu Li","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.01.018","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.01.018","url":null,"abstract":"炎症性肠病（IBD）包括克罗恩病和溃疡性结肠炎。脑-肠轴可通过心理-神经-内分泌-免疫调节在IBD发生、发展中发挥重要作用，通过MRI来观察及研究IBD患者的脑结构及脑功能异常，特别是脑功能异常的观察，有利于更深层次地理解IBD的发病机制，并从神经方向寻找新的治疗方法可能有效减轻肠道炎症或缓解腹痛症状。","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44478654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-10DOI: 10.3760/CMA.J.ISSN.1005-1201.2020.01.012
Z. Gao, Wang Yigeng, Haijie Li, Jiangfen Wu, Z. Ye
Objective To investigate the value of radiomics in image quality control with low-dose CT examination of solid pulmonary nodules. Methods Images were acquired on CT750 HD scanner, and chest pulmonary nodules phantom were scanned at different tube voltage and tube current. The radiation dose CTDIvol under different scanning conditions were recorded, as well as CNR and SNR of each scanning sequence. The variation of radiation dose, noise, tube voltage and tube current were analyzed. All data were analyzed by radiomics analysis software. R language statistics software was adopted to analyze the extracted features by principal component analysis (PCA), and the characteristic parameters with the largest contribution rate to image quality were selected for analysis. One-way ANOVA was used to analyze all the important characteristic parameters to reveal the difference of characteristic parameters under different tube voltages. Finally, the post-test method was used to find out the differences among different tube voltage groups. Results Radiation dose rised linearly with the increase of tube current and tube voltage. Although the overall change trend of SNR and CNR in pulmonary nodules was linearly related to the change of tube voltage and tube current, there was no clear change trend threshold at low dose, which could not accurately evaluate the image quality under low radiation. Both CNR and SNR cannot evaluate the image quality effectively, and have no practiced value for optimizing the low dose scanning parameters. There main components including Uniformity, Voxel Value Sum, and Haralick Correlation extracted by radiomics analysis software were proved to play a critical role in image quality control. The cumulative contribution rate of variance was 89.20% and the eigen values were greater than 1. Uniformity curve of characteristic parameter showed that the trend of change was correlated with the change of tube voltage and tube current, and the stability and consistency were good. Uniformity one-way ANOVA analysis showed that when the tube voltage reduced from 140 to 120 kVp, there was no difference (P=0.117) in the uniformity, while from 120 to 80 kVp, significant differences revealed (P<0.001). Considering tube current, no significant variation was observed in uniformity when current was greater than 90 mA, which indicated that tube current of 90 mA could lead to better image quality. Conclusion Radiomics analysis can effectively evaluate and control the CT image quality of low dose solid pulmonary nodules. Key words: Radiation dosage; Pulmonary nodule; Phantoms
{"title":"Phantom study in the quality control of low dose solid pulmonary nodule CT based on radiomics analysis","authors":"Z. Gao, Wang Yigeng, Haijie Li, Jiangfen Wu, Z. Ye","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.01.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.01.012","url":null,"abstract":"Objective \u0000To investigate the value of radiomics in image quality control with low-dose CT examination of solid pulmonary nodules. \u0000 \u0000 \u0000Methods \u0000Images were acquired on CT750 HD scanner, and chest pulmonary nodules phantom were scanned at different tube voltage and tube current. The radiation dose CTDIvol under different scanning conditions were recorded, as well as CNR and SNR of each scanning sequence. The variation of radiation dose, noise, tube voltage and tube current were analyzed. All data were analyzed by radiomics analysis software. R language statistics software was adopted to analyze the extracted features by principal component analysis (PCA), and the characteristic parameters with the largest contribution rate to image quality were selected for analysis. One-way ANOVA was used to analyze all the important characteristic parameters to reveal the difference of characteristic parameters under different tube voltages. Finally, the post-test method was used to find out the differences among different tube voltage groups. \u0000 \u0000 \u0000Results \u0000Radiation dose rised linearly with the increase of tube current and tube voltage. Although the overall change trend of SNR and CNR in pulmonary nodules was linearly related to the change of tube voltage and tube current, there was no clear change trend threshold at low dose, which could not accurately evaluate the image quality under low radiation. Both CNR and SNR cannot evaluate the image quality effectively, and have no practiced value for optimizing the low dose scanning parameters. There main components including Uniformity, Voxel Value Sum, and Haralick Correlation extracted by radiomics analysis software were proved to play a critical role in image quality control. The cumulative contribution rate of variance was 89.20% and the eigen values were greater than 1. Uniformity curve of characteristic parameter showed that the trend of change was correlated with the change of tube voltage and tube current, and the stability and consistency were good. Uniformity one-way ANOVA analysis showed that when the tube voltage reduced from 140 to 120 kVp, there was no difference (P=0.117) in the uniformity, while from 120 to 80 kVp, significant differences revealed (P<0.001). Considering tube current, no significant variation was observed in uniformity when current was greater than 90 mA, which indicated that tube current of 90 mA could lead to better image quality. \u0000 \u0000 \u0000Conclusion \u0000Radiomics analysis can effectively evaluate and control the CT image quality of low dose solid pulmonary nodules. \u0000 \u0000 \u0000Key words: \u0000Radiation dosage; Pulmonary nodule; Phantoms","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44587698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-10DOI: 10.3760/CMA.J.ISSN.1005-1201.2020.01.010
C. Lyu, K. Gao, Qiang Huang, J. Gong, Yong Zhang, Jian-Feng Wang
Objective To evaluate the safety and efficacy of balloon pulmonary angioplasty (BPA) in the treatment of chronic thromboembolic pulmonary hypertension (CTEPH). Methods A study was conducted on 25 patients consisting of 10 males and 15 females with CTEPH who received BPA treatment from February 2017 to May 2018 in Beijing Chaoyang Hospital, Capital Medical University. The changes of brain natriuretic peptide (BNP), mean pulmonary artery pressure (mPAP), tricuspid annulus systolic plane excursion (TAPSE), six-minute walking test (6WMD), right ventricular basement diameter and WHO cardiac function grading were compared before and after treatment with BPA using paired t test. Results Twenty-five patients received a total of 50 BPA treatments, and among them, 12 patients received two or more times. The mPAP decreased from (50.4±9.9) mmHg (1 mmHg=0.133 kPa) to (39.9±10.6) mmHg before and after operation, and the difference was statistically significant (t=9.7, P<0.001); BNP decreased from (513.5±357.3) pg/ml to (106.3±137.53) pg/ml, and the difference was significant (t=3.2, P=0.006); TAPSE increased from (16.2±2.8) mm to (18.0±2.4) mm, and the difference was statistically significant (t=-5.7, P=0.002); the right ventricular base diameter decreased from (45.9±6.9) mm to (41.2±7.3) mm, and the difference was statistically significant (t=5.6, P<0.001); 6WMD increased from (371.1±86.8) m to (467.7±76.1) m, with statistical significance (t=-6.4, P<0.001); WHO cardiac function grading was improved from (2.4±0.7) to (1.2±0.4) after surgery, and the difference was statistically significant (t=2.8, P=0.021). Pulmonary artery injury occurred in 3 patients and 2 patients had hemoptysis.The hemoptysis was stopped after arterial embolization. No other complications such as pulmonary edema occurred. Conclusion BPA may improve clinical status and hemodynamics of patients with CTEPH, which offers an alternative approach of treatment in patients with inoperable CTEPH. Key words: Pulmonary embolism; Chronic disease; Hypertension, pulmonary; Angioplasty, balloon; Treatment outcome
{"title":"Safety and efficacy of balloon pulmonary angioplasty in the treatment of chronic thromboembolic pulmonary hypertension","authors":"C. Lyu, K. Gao, Qiang Huang, J. Gong, Yong Zhang, Jian-Feng Wang","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.01.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.01.010","url":null,"abstract":"Objective \u0000To evaluate the safety and efficacy of balloon pulmonary angioplasty (BPA) in the treatment of chronic thromboembolic pulmonary hypertension (CTEPH). \u0000 \u0000 \u0000Methods \u0000A study was conducted on 25 patients consisting of 10 males and 15 females with CTEPH who received BPA treatment from February 2017 to May 2018 in Beijing Chaoyang Hospital, Capital Medical University. The changes of brain natriuretic peptide (BNP), mean pulmonary artery pressure (mPAP), tricuspid annulus systolic plane excursion (TAPSE), six-minute walking test (6WMD), right ventricular basement diameter and WHO cardiac function grading were compared before and after treatment with BPA using paired t test. \u0000 \u0000 \u0000Results \u0000Twenty-five patients received a total of 50 BPA treatments, and among them, 12 patients received two or more times. The mPAP decreased from (50.4±9.9) mmHg (1 mmHg=0.133 kPa) to (39.9±10.6) mmHg before and after operation, and the difference was statistically significant (t=9.7, P<0.001); BNP decreased from (513.5±357.3) pg/ml to (106.3±137.53) pg/ml, and the difference was significant (t=3.2, P=0.006); TAPSE increased from (16.2±2.8) mm to (18.0±2.4) mm, and the difference was statistically significant (t=-5.7, P=0.002); the right ventricular base diameter decreased from (45.9±6.9) mm to (41.2±7.3) mm, and the difference was statistically significant (t=5.6, P<0.001); 6WMD increased from (371.1±86.8) m to (467.7±76.1) m, with statistical significance (t=-6.4, P<0.001); WHO cardiac function grading was improved from (2.4±0.7) to (1.2±0.4) after surgery, and the difference was statistically significant (t=2.8, P=0.021). Pulmonary artery injury occurred in 3 patients and 2 patients had hemoptysis.The hemoptysis was stopped after arterial embolization. No other complications such as pulmonary edema occurred. \u0000 \u0000 \u0000Conclusion \u0000BPA may improve clinical status and hemodynamics of patients with CTEPH, which offers an alternative approach of treatment in patients with inoperable CTEPH. \u0000 \u0000 \u0000Key words: \u0000Pulmonary embolism; Chronic disease; Hypertension, pulmonary; Angioplasty, balloon; Treatment outcome","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49478031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-10DOI: 10.3760/CMA.J.ISSN.1005-1201.2020.01.013
Hai-long Zhou, Yafei Qi, Cheng-yu Lin, Yonglan He, Xiaoqi Wang, S. Deng, Ying Zhang, Yuan Li, Huadan Xue, F. Feng, H. Fu, Zhengyu Jin
Objective To explore the application value of 3.0 T MultiVane XD (MVXD) technique in female patients with uterine adenomyosis and fibroids. Methods Patients diagnosed with uterine fibroids with ultrasound and suspected of adenomyosis were involved prospectively from March to May 2018, 3.0 T pelvic MRI examinations were performed during peri-ovulatory period. Axialconventional turbo spin echo (TSE) T2WI, axial MVXD T2WI, sagittal conventional TSE T2WI and MVXD sagittal T2WI were acquired. Two observers rated those 4 series in the aspects of sharpness of uterine border, motion artifacts, identification capability of lesions, confidence of diagnosis and overall image quality. Cohen Kappa analysis was used to evaluate the consistency of scores between 2 observers. Scores of TSE T2WI and MVXD T2WI qualities were compared using Wilcoxon matched-pairs signed-ranks test. Results Twenty patients were enrolled. Axial conventional TSE T2WI, axial MVXD T2WI were aquired on all of them. Sagittal conventional TSE T2WI, sagittal MVXD T2WI were aquired on 19 among them. Nine patients had only obvious adenomyosis, 6 had only uterinefibroids, and 5 had adenomyosis and uterine fibroids. Compared to conventional TSE technique, scores of two observers in the sharpness of uterine border, motion artifacts, and overall image quality is higher by MVXD with significant difference (P<0.05). The Kappa values for image quality scores of two observers ranged from 0.615 to 0.971, the agreement was good or very good. Conclusion Applying MVXD T2WI technique to patients with uterine fibroids and adenomyosiscould improve image quality, without sacrificing the ability to recognize and diagnose lesions, compared to conventional TSE T2WI technique. Key words: Adenomyosis; Uterine fibroids; Magnetic resonance imaging; MultiVane XD technique
{"title":"T2WI female pelvic MRI using the MultiVane XD technique at 3.0 T in uterine adenomyosis and fibroids: a preliminary study","authors":"Hai-long Zhou, Yafei Qi, Cheng-yu Lin, Yonglan He, Xiaoqi Wang, S. Deng, Ying Zhang, Yuan Li, Huadan Xue, F. Feng, H. Fu, Zhengyu Jin","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.01.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.01.013","url":null,"abstract":"Objective \u0000To explore the application value of 3.0 T MultiVane XD (MVXD) technique in female patients with uterine adenomyosis and fibroids. \u0000 \u0000 \u0000Methods \u0000Patients diagnosed with uterine fibroids with ultrasound and suspected of adenomyosis were involved prospectively from March to May 2018, 3.0 T pelvic MRI examinations were performed during peri-ovulatory period. Axialconventional turbo spin echo (TSE) T2WI, axial MVXD T2WI, sagittal conventional TSE T2WI and MVXD sagittal T2WI were acquired. Two observers rated those 4 series in the aspects of sharpness of uterine border, motion artifacts, identification capability of lesions, confidence of diagnosis and overall image quality. Cohen Kappa analysis was used to evaluate the consistency of scores between 2 observers. Scores of TSE T2WI and MVXD T2WI qualities were compared using Wilcoxon matched-pairs signed-ranks test. \u0000 \u0000 \u0000Results \u0000Twenty patients were enrolled. Axial conventional TSE T2WI, axial MVXD T2WI were aquired on all of them. Sagittal conventional TSE T2WI, sagittal MVXD T2WI were aquired on 19 among them. Nine patients had only obvious adenomyosis, 6 had only uterinefibroids, and 5 had adenomyosis and uterine fibroids. Compared to conventional TSE technique, scores of two observers in the sharpness of uterine border, motion artifacts, and overall image quality is higher by MVXD with significant difference (P<0.05). The Kappa values for image quality scores of two observers ranged from 0.615 to 0.971, the agreement was good or very good. \u0000 \u0000 \u0000Conclusion \u0000Applying MVXD T2WI technique to patients with uterine fibroids and adenomyosiscould improve image quality, without sacrificing the ability to recognize and diagnose lesions, compared to conventional TSE T2WI technique. \u0000 \u0000 \u0000Key words: \u0000Adenomyosis; Uterine fibroids; Magnetic resonance imaging; MultiVane XD technique","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45933766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vascular involvement with neurofibromatosis type I: a case report","authors":"Yong Jiang, H. Shi, Y. Liu","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.01.015","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.01.015","url":null,"abstract":"本文报道一例血管受累的Ⅰ型神经纤维瘤病（NFI）。患者，男，43岁，初期确诊为NFI型时，其右侧椎动脉假性动脉瘤在MRI检查中被漏诊，3年后因右上臂疼痛而行MRI检查发现颈6椎体水平右旁臂丛神经走行区类椭圆形异常信号，T2WI示壁及部分瘤体呈低信号、T1WI及液体衰减反转恢复序列（FLAIR）呈高信号，病变较3年前范围增大，影像误诊为神经纤维瘤，最终诊断为右侧椎动脉假性动脉瘤，病变同时累及右侧椎动脉、右侧锁骨下动脉及胸廓内动脉等多处血管。","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48240189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-10DOI: 10.3760/CMA.J.ISSN.1005-1201.2020.01.006
Weichuan Ye, Chunmiao Chen, Xulu Wu, Dengke Zhang, Dan Liu, Jie Li, Zhongwei Zhao, Huang Xianghua
Objective To explore and clarify the correlation between short-term aggressive intrasegmental recurrence (AIR) and functional magnetic resonance imaging after radiofrequency ablation of hepatocellular carcinoma (HCC). Methods A retrospective analysis of 1 262 patients with HCC who underwent radiofrequency ablation (RFA) in our hospital from January 2012 to June 2018, all patients were confirmed by pathology as HCC, of which 30 patients were found to have AIR during radiographic follow-up within 3 months after surgery, another 35 patients with disease progression who were controlled in a short period of time were randomly selected as the control group. All the enrolled patients underwent dynamic enhanced magnetic resonance imaging (DCE-MRI) and diffusion weighted imaging (DWI) scanning before surgery, and the differences in clinical data, lesion location, and functional magnetic resonance parameters between the two groups were compared, and their correlation with AIR after RFA was analyzed. Chi-square test, t test and Pearson test were used. Results The lesions in the AIR group were significantly more in the Ⅰand Ⅳsegments than that in the control group (P 0.05). There was no significant difference in the lesion morphology between the two groups (P>0.05), and there was a significant difference in the early enhancement pattern of the lesions (P<0.05), and the early arterial enhancement rate and apparent diffusion coefficient (ADC) value of the AIR group were significantly lower than the control group (P<0.05). Further correlation analysis found that early enhancement of the arterial artery, early arterial enhancement rate, ADC value and lesion location were associated with AIR and were positively correlated, r values were 0.455, 0.633, 0.518, 0.375 and 0.287 (P<0.05). Conclusion The short-term AIR and functional imaging parameters (arterial early enhancement, early arterial enhancement rate, ADC value) and the liver segment (Ⅰ and Ⅳ) were highly correlated with radiofrequency ablation. Key words: Liver neoplasms; Radiofrequency ablation; Aggressive intrasegmental recurrence; Magnetic resonance imaging
{"title":"Correlation analysis between short-term invasive recurrence and functional MRI after radiofrequency ablation of hepatocellular carcinoma","authors":"Weichuan Ye, Chunmiao Chen, Xulu Wu, Dengke Zhang, Dan Liu, Jie Li, Zhongwei Zhao, Huang Xianghua","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.01.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.01.006","url":null,"abstract":"Objective \u0000To explore and clarify the correlation between short-term aggressive intrasegmental recurrence (AIR) and functional magnetic resonance imaging after radiofrequency ablation of hepatocellular carcinoma (HCC). \u0000 \u0000 \u0000Methods \u0000A retrospective analysis of 1 262 patients with HCC who underwent radiofrequency ablation (RFA) in our hospital from January 2012 to June 2018, all patients were confirmed by pathology as HCC, of which 30 patients were found to have AIR during radiographic follow-up within 3 months after surgery, another 35 patients with disease progression who were controlled in a short period of time were randomly selected as the control group. All the enrolled patients underwent dynamic enhanced magnetic resonance imaging (DCE-MRI) and diffusion weighted imaging (DWI) scanning before surgery, and the differences in clinical data, lesion location, and functional magnetic resonance parameters between the two groups were compared, and their correlation with AIR after RFA was analyzed. Chi-square test, t test and Pearson test were used. \u0000 \u0000 \u0000Results \u0000The lesions in the AIR group were significantly more in the Ⅰand Ⅳsegments than that in the control group (P 0.05). There was no significant difference in the lesion morphology between the two groups (P>0.05), and there was a significant difference in the early enhancement pattern of the lesions (P<0.05), and the early arterial enhancement rate and apparent diffusion coefficient (ADC) value of the AIR group were significantly lower than the control group (P<0.05). Further correlation analysis found that early enhancement of the arterial artery, early arterial enhancement rate, ADC value and lesion location were associated with AIR and were positively correlated, r values were 0.455, 0.633, 0.518, 0.375 and 0.287 (P<0.05). \u0000 \u0000 \u0000Conclusion \u0000The short-term AIR and functional imaging parameters (arterial early enhancement, early arterial enhancement rate, ADC value) and the liver segment (Ⅰ and Ⅳ) were highly correlated with radiofrequency ablation. \u0000 \u0000 \u0000Key words: \u0000Liver neoplasms; Radiofrequency ablation; Aggressive intrasegmental recurrence; Magnetic resonance imaging","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43147210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Drug-coated balloon for intracranial in-stent restenosis: a long-term follow-up case report","authors":"Bin Xu, W. Bai, Zi-liang Wang","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.01.017","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.01.017","url":null,"abstract":"支架成形术治疗缺血性脑血管病远期支架内再狭窄导致的症状复发，限制了颅内支架的应用与发展。借鉴药物涂层球囊（DCB）治疗冠状动脉支架内再狭窄的成功经验，笔者尝试应用DCB治疗1例脑血管支架内反复再狭窄患者，取得了良好效果。","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47188464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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