Pub Date : 2020-02-10DOI: 10.3760/CMA.J.ISSN.1005-1201.2020.02.003
Maoqing Hu, F. Long, W. Long, Menghuang Wen, Zaiyi Liu, C. Liang
Objective To evaluate the effect of height (HT), total body weight (TBW), body mass index (BMI), lean body weight (LBW), body surface area (BSA) and blood volume (BV) on aortic and liver contrast enhancement during upper abdominal contrast-enhanced CT scans. Methods One hundred and thirteen enrolled patients underwent upper abdominal multiphase contrast-enhanced CT scans. The enhancement (ΔHU) of aorta in hepatic arterial phase and liver parenchyma in portal venous phase were measured and calculated. The ΔHU values difference of aorta and liver parenchyma in subgroups between males and females, TBW<60 kg and TBW≥60 kg, BMI<25 kg/m2 and BMI≥25 kg/m2 were compared. To evaluate the effect of the patient′s body parameters on aortic and hepatic enhancement, we performed simple linear regression analyses between the change in CT numbers per gram of iodine (ΔHU/gI) at aorta and liver and each of the following: HT, TBW, BMI, LBW, BSA, and BV. Pearson and t test were used. Results The mean ΔHU values of aorta and liver were significantly lower at males than that of at females (P<0.05). They were higher at TBW<60 kg patients than at TBW≥60 kg patients(P<0.05), and the mean ΔHU values of the liver at BMI<25 kg/m2 patients were significantly higher than at BMI≥25 kg/m2 patients(P<0.05). The proportion of the ΔHU values at liver less than 50 HU was higher at males (18.3%, 11/60) than at females (7.5%, 4/53). The most obvious negative correlation coefficients were found between the ΔHU/gI of aorta and LBW at hepatic arterial phase (r=-0.559, P<0.01), and between the ΔHU/gI of liver and BSA at portal venous phase (r=-0.680, P<0.01). Conclusion LBW or BSA could be the alternative body index to TBW for the calculation of personalized iodine dose protocol at aortic and liver enhanced CT scans. Key words: Contrast media; Tomography, X-ray computed; Aorta; Liver
{"title":"The aortic and hepatic contrast enhancement at CT and its correlations with various body size index","authors":"Maoqing Hu, F. Long, W. Long, Menghuang Wen, Zaiyi Liu, C. Liang","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.02.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.02.003","url":null,"abstract":"Objective \u0000To evaluate the effect of height (HT), total body weight (TBW), body mass index (BMI), lean body weight (LBW), body surface area (BSA) and blood volume (BV) on aortic and liver contrast enhancement during upper abdominal contrast-enhanced CT scans. \u0000 \u0000 \u0000Methods \u0000One hundred and thirteen enrolled patients underwent upper abdominal multiphase contrast-enhanced CT scans. The enhancement (ΔHU) of aorta in hepatic arterial phase and liver parenchyma in portal venous phase were measured and calculated. The ΔHU values difference of aorta and liver parenchyma in subgroups between males and females, TBW<60 kg and TBW≥60 kg, BMI<25 kg/m2 and BMI≥25 kg/m2 were compared. To evaluate the effect of the patient′s body parameters on aortic and hepatic enhancement, we performed simple linear regression analyses between the change in CT numbers per gram of iodine (ΔHU/gI) at aorta and liver and each of the following: HT, TBW, BMI, LBW, BSA, and BV. Pearson and t test were used. \u0000 \u0000 \u0000Results \u0000The mean ΔHU values of aorta and liver were significantly lower at males than that of at females (P<0.05). They were higher at TBW<60 kg patients than at TBW≥60 kg patients(P<0.05), and the mean ΔHU values of the liver at BMI<25 kg/m2 patients were significantly higher than at BMI≥25 kg/m2 patients(P<0.05). The proportion of the ΔHU values at liver less than 50 HU was higher at males (18.3%, 11/60) than at females (7.5%, 4/53). The most obvious negative correlation coefficients were found between the ΔHU/gI of aorta and LBW at hepatic arterial phase (r=-0.559, P<0.01), and between the ΔHU/gI of liver and BSA at portal venous phase (r=-0.680, P<0.01). \u0000 \u0000 \u0000Conclusion \u0000LBW or BSA could be the alternative body index to TBW for the calculation of personalized iodine dose protocol at aortic and liver enhanced CT scans. \u0000 \u0000 \u0000Key words: \u0000Contrast media; Tomography, X-ray computed; Aorta; Liver","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43420825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To analyze the function of essential hypertension′s working memory network by using task-fMRI and independent component analysis (ICA). Methods According to the enrollment criteria, 24 hypertensive patients and 23 healthy controls (May 2016 to January 2017) in the 900 Hospital of the Joint Service Support Force were collected, who underwent task-state functional MRI data acquisition of N-back by using Siemens 3.0 T MRI. All subjects completed neuropsychological cognitive tests, blood pressure measurements and biochemical tests before MRI. Task-state functional MRI was analyzed by SPM 12, and independent component analysis was performed by GIFT 4.0 software. The independent-samples t-test was used to analyze the maps of the two groups′s task-state fMRI and ICA. The results were adjusted by multiple comparison correction of Alphasim, P<0.05 showed that the difference was statistically significant. Results Compared with the healthy group, the activation of left superior frontal gyrus and left middle frontal gyrus in hypertension group was enhanced (P<0.05), but there was no obvious weakened activation area. In the independent component analysis, the functional connectivity of left middle frontal gyrus and left anterior central gyrus in hypertension group was significantly lower than that in healthy control group (P<0.05), and there was no significant enhancement of functional connectivity. Conclusions The working memory network of patients with essential hypertension may change abnormally due to the influence of long-term hypertension. This kind of damage can compensate through the functional enhancement of brain regions, thus maintaining the normal cognitive level of hypertensive patients. Key words: Hypertension; Magnetic resonance imaging; Memory
目的应用任务-功能磁共振成像(task-fMRI)和独立分量分析(ICA)分析原发性高血压患者工作记忆网络的功能。方法根据入组标准，收集2016年5月~ 2017年1月联勤保障部队900医院高血压患者24例和健康对照23例，采用Siemens 3.0 T MRI采集N-back任务状态功能MRI数据。所有受试者在MRI前完成神经心理认知测试、血压测量和生化测试。采用spm12分析任务状态功能MRI，采用GIFT 4.0软件进行独立成分分析。采用独立样本t检验分析两组的任务状态fMRI和ICA图谱。结果经Alphasim多重比较校正，P<0.05为差异有统计学意义。结果与健康组比较，高血压组左额上回和左额中回活化增强(P<0.05)，但活化区未见明显减弱。独立成分分析中，高血压组左额中回和左中央前回功能连通性显著低于健康对照组(P<0.05)，功能连通性无显著增强。结论原发性高血压患者的工作记忆网络可能因长期高血压的影响而发生异常变化。这种损伤可通过脑区功能增强进行补偿，从而维持高血压患者正常的认知水平。关键词:高血压;磁共振成像;内存
{"title":"The study on cognitive changes of working memory network in patients with essential hypertension based on task-functional MRI","authors":"Xiaoyang Wang, Dandan Lin, Haoxue Yu, Hui Li, Zhi-qiang Huang, Shangwen Xu","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.02.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.02.007","url":null,"abstract":"Objective \u0000To analyze the function of essential hypertension′s working memory network by using task-fMRI and independent component analysis (ICA). \u0000 \u0000 \u0000Methods \u0000According to the enrollment criteria, 24 hypertensive patients and 23 healthy controls (May 2016 to January 2017) in the 900 Hospital of the Joint Service Support Force were collected, who underwent task-state functional MRI data acquisition of N-back by using Siemens 3.0 T MRI. All subjects completed neuropsychological cognitive tests, blood pressure measurements and biochemical tests before MRI. Task-state functional MRI was analyzed by SPM 12, and independent component analysis was performed by GIFT 4.0 software. The independent-samples t-test was used to analyze the maps of the two groups′s task-state fMRI and ICA. The results were adjusted by multiple comparison correction of Alphasim, P<0.05 showed that the difference was statistically significant. \u0000 \u0000 \u0000Results \u0000Compared with the healthy group, the activation of left superior frontal gyrus and left middle frontal gyrus in hypertension group was enhanced (P<0.05), but there was no obvious weakened activation area. In the independent component analysis, the functional connectivity of left middle frontal gyrus and left anterior central gyrus in hypertension group was significantly lower than that in healthy control group (P<0.05), and there was no significant enhancement of functional connectivity. \u0000 \u0000 \u0000Conclusions \u0000The working memory network of patients with essential hypertension may change abnormally due to the influence of long-term hypertension. This kind of damage can compensate through the functional enhancement of brain regions, thus maintaining the normal cognitive level of hypertensive patients. \u0000 \u0000 \u0000Key words: \u0000Hypertension; Magnetic resonance imaging; Memory","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43898598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-10DOI: 10.3760/CMA.J.ISSN.1005-1201.2020.02.005
Pengjun Chen, Guangfeng Lin, Chenying Lu, Suhang Chen, J. Hui, Zhongwei Zhao, Jiansong Ji
Objective To evaluate image quality and radiation dosage of CT cerebral perfusion (CTP) imaging of 70 kV with different tube current and scanning passes and its diagnostic value for hyperacute cerebral infarction. Methods A total of 190 patients with suspected hyperacute cerebral infarction in Lishui Central Hospital of Zhejiang Province from December 2017 to February 2019 were selected prospectively, and all patients were divided into 4 groups according to random number table and received non-contrast CT examination and dual-source CT cerebral perfusion imaging with 70 kV protocol simultaneously within 6 hours after the onset of symptoms: group A, 120 mA, 21 scanning time points; group B, 100 mA, 21 scanning time points; group C, 100 mA, 17 scanning time points; group D, 80 mA, 21 scanning time points. The values of perfusion parameters such as cerebral blood flow (CBF), crerbral blood volume (CBV), mean transit time (MTT), time to peak (TTP) were acquired. Image quality was evaluated and effective dose (ED) was recorded. The quantitative variables of image quality and radiation dosage were compared between four groups using one-way analysis of variance test. Results There was no differences between groups on the CBF, CBV, MTT, TTP maps for all CTP values (P>0.05), and all images could meet the diagnostic requirements. The subjective image quality score of vessel sharpness and overall image quality of both internal carotid artery and middle cerebral artery and the degree of noise of internal carotid in artery in group A was higher than that in group D (P<0.05). The score of vessel sharpness of internal carotid in artery ingroup A was higher than those in both groups B and C (P<0.05). The scores of vessel sharpness of both internal carotid artery and middle cerebral artery internal carotid in artery ingroups B and C were higher than that in group A (P<0.05). The mean EDs of non-contrast CT in group A, B, C, D were 1.10, 2.11, 1.76, 1.42, 1.40 mSv; compared to group A, ED was reduced approximately 16.6% (0.35/2.11), 32.7% (0.69/2.11) and 33.6% (0.71/2.11), respectively (P<0.05). The diagnostic accuracy of low dose dual source CTP for detecting hyperacute cerebral infarction was 93.5% (172/184), while that of non-contrast CT was 52.2% (96/184);for detecting hyperacutelacunar cerebral infarction, it was 72.1% (31/43) and 16.3% (7/43) respectively (P<0.05). Conclusion Appropriate reduction of tube current (100 mA) and scanning passes (17 scanning time points) can reduce the radiation dosage and acquire comparable image quality for 70 kV protocol CTP. Compared with non-contrast CT, low dose dual-source CTP is more sensitive to hyperacute cerebral infarction, especially hyperacute lacunar cerebral infarction. Key words: Cerebral infarction; Radiation dosage; Tomography, X-ray computed
{"title":"Diagnostic value of low dose dual-source CT cerebral perfusion imaging in patients with hyperacute cerebral infarction","authors":"Pengjun Chen, Guangfeng Lin, Chenying Lu, Suhang Chen, J. Hui, Zhongwei Zhao, Jiansong Ji","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.02.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.02.005","url":null,"abstract":"Objective \u0000To evaluate image quality and radiation dosage of CT cerebral perfusion (CTP) imaging of 70 kV with different tube current and scanning passes and its diagnostic value for hyperacute cerebral infarction. \u0000 \u0000 \u0000Methods \u0000A total of 190 patients with suspected hyperacute cerebral infarction in Lishui Central Hospital of Zhejiang Province from December 2017 to February 2019 were selected prospectively, and all patients were divided into 4 groups according to random number table and received non-contrast CT examination and dual-source CT cerebral perfusion imaging with 70 kV protocol simultaneously within 6 hours after the onset of symptoms: group A, 120 mA, 21 scanning time points; group B, 100 mA, 21 scanning time points; group C, 100 mA, 17 scanning time points; group D, 80 mA, 21 scanning time points. The values of perfusion parameters such as cerebral blood flow (CBF), crerbral blood volume (CBV), mean transit time (MTT), time to peak (TTP) were acquired. Image quality was evaluated and effective dose (ED) was recorded. The quantitative variables of image quality and radiation dosage were compared between four groups using one-way analysis of variance test. \u0000 \u0000 \u0000Results \u0000There was no differences between groups on the CBF, CBV, MTT, TTP maps for all CTP values (P>0.05), and all images could meet the diagnostic requirements. The subjective image quality score of vessel sharpness and overall image quality of both internal carotid artery and middle cerebral artery and the degree of noise of internal carotid in artery in group A was higher than that in group D (P<0.05). The score of vessel sharpness of internal carotid in artery ingroup A was higher than those in both groups B and C (P<0.05). The scores of vessel sharpness of both internal carotid artery and middle cerebral artery internal carotid in artery ingroups B and C were higher than that in group A (P<0.05). The mean EDs of non-contrast CT in group A, B, C, D were 1.10, 2.11, 1.76, 1.42, 1.40 mSv; compared to group A, ED was reduced approximately 16.6% (0.35/2.11), 32.7% (0.69/2.11) and 33.6% (0.71/2.11), respectively (P<0.05). The diagnostic accuracy of low dose dual source CTP for detecting hyperacute cerebral infarction was 93.5% (172/184), while that of non-contrast CT was 52.2% (96/184);for detecting hyperacutelacunar cerebral infarction, it was 72.1% (31/43) and 16.3% (7/43) respectively (P<0.05). \u0000 \u0000 \u0000Conclusion \u0000Appropriate reduction of tube current (100 mA) and scanning passes (17 scanning time points) can reduce the radiation dosage and acquire comparable image quality for 70 kV protocol CTP. Compared with non-contrast CT, low dose dual-source CTP is more sensitive to hyperacute cerebral infarction, especially hyperacute lacunar cerebral infarction. \u0000 \u0000 \u0000Key words: \u0000Cerebral infarction; Radiation dosage; Tomography, X-ray computed","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45092415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CT and MRI findings of granulosa cell tumor in extraocular muscle","authors":"M. Qi, N. Lin, Yaru Sheng, Ting Yuan, Y. Sha","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.02.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.02.013","url":null,"abstract":"笔者报道3例眼肌颗粒细胞瘤（GCT）的影像及病理表现。GCT的影像特点为肿块以肌腹为中心，CT上呈均匀等或稍高密度；常规MRI，相对于脑灰质，肿块于T1WI呈等信号、T2WI上呈低信号，增强扫描呈中等至显著强化；扩散加权成像呈等或稍低信号，平均表观扩散系数为0.60×10-3 mm2/s。GCT的病理特点为瘤细胞体积大，且细胞排列紧密，胞质充满嗜酸性颗粒，S-100表达强阳性。","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45054386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-10DOI: 10.3760/CMA.J.ISSN.1005-1201.2020.02.011
Li Li, Wen Liu, Y. Yin, Chunwang Li, Ke Jin
Objective To investigate the CT features of hepatoblastoma in term neonates. Methods The clinical data and abdominal CT features of 7 children with neonatal hepatoblastoma confirmed by surgical pathology from January 2015 to January 2019 in Hunan Children′s Hospital were retrospectively analyzed, focusing on the position, size, shape, density and dynamic enhancement characteristics of the mass. Results All 7 cases were solitary intrahepatic mass, which affected the liver SⅥ in 2 cases, SⅦ in 2 cases, SⅤ+Ⅵ in 1 case, SⅡ+Ⅲ in 1 case, SⅣa+Ⅴ+Ⅷ in 1 case. The maximum diameters were 2.9-10.2 cm (median maximum diameter 4.7 cm). Four cases tumors were spherical shape, while 3 cases were irregular lobulation and extended to the outside of live. The boundary was clear in 6 cases and fuzzy in 1 case. Necrosis, calcification, patchy hemorrhage was shown in 4 cases, 1 case, 5 cases, respectively. All 7 cases tumors showed heterogeneous enhancement, with multiple nodular and lamellar obvious enhancement at the center and edge of the tumor in arterial phase, and gradually filling-in, presented as multiple bands and island-like enhancement, with prominent edge enhanced but no enhancement in the necrotic area in portal venous and delayed phase. The tumor invaded portal vein and bile duct in hilar area in 1 case, with the intra-hepatic bile duct dilation. The caliber of the abdominal aorta below celiac trunk became thinner in 3 cases. 6 cases were epithelial fetal type and 1 case was mixed type with pathological confirmed. Conclusion The main CT manifestations of neonatal hepatoblastoma are spherical or lobulated, with varied degrees of necrotic, hemorrhage and calcification, and heterogeneous enhancement with gradually regional expansion. Key words: Neonates; Hepatoblastoma; Tomomography, X-ray computed; Alpha fetoprotein
{"title":"The CT imaging features of hepatoblastoma in term neonates","authors":"Li Li, Wen Liu, Y. Yin, Chunwang Li, Ke Jin","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.02.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.02.011","url":null,"abstract":"Objective \u0000To investigate the CT features of hepatoblastoma in term neonates. \u0000 \u0000 \u0000Methods \u0000The clinical data and abdominal CT features of 7 children with neonatal hepatoblastoma confirmed by surgical pathology from January 2015 to January 2019 in Hunan Children′s Hospital were retrospectively analyzed, focusing on the position, size, shape, density and dynamic enhancement characteristics of the mass. \u0000 \u0000 \u0000Results \u0000All 7 cases were solitary intrahepatic mass, which affected the liver SⅥ in 2 cases, SⅦ in 2 cases, SⅤ+Ⅵ in 1 case, SⅡ+Ⅲ in 1 case, SⅣa+Ⅴ+Ⅷ in 1 case. The maximum diameters were 2.9-10.2 cm (median maximum diameter 4.7 cm). Four cases tumors were spherical shape, while 3 cases were irregular lobulation and extended to the outside of live. The boundary was clear in 6 cases and fuzzy in 1 case. Necrosis, calcification, patchy hemorrhage was shown in 4 cases, 1 case, 5 cases, respectively. All 7 cases tumors showed heterogeneous enhancement, with multiple nodular and lamellar obvious enhancement at the center and edge of the tumor in arterial phase, and gradually filling-in, presented as multiple bands and island-like enhancement, with prominent edge enhanced but no enhancement in the necrotic area in portal venous and delayed phase. The tumor invaded portal vein and bile duct in hilar area in 1 case, with the intra-hepatic bile duct dilation. The caliber of the abdominal aorta below celiac trunk became thinner in 3 cases. 6 cases were epithelial fetal type and 1 case was mixed type with pathological confirmed. \u0000 \u0000 \u0000Conclusion \u0000The main CT manifestations of neonatal hepatoblastoma are spherical or lobulated, with varied degrees of necrotic, hemorrhage and calcification, and heterogeneous enhancement with gradually regional expansion. \u0000 \u0000 \u0000Key words: \u0000Neonates; Hepatoblastoma; Tomomography, X-ray computed; Alpha fetoprotein","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47025437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To investigate the feasibility of one-step coronary and carotid-cerebrovascular computed tomography angiography (CTA) using high-pitch Double Turbo Flash mode and to analyze the image quality and radiation dose in patients with heart rate variability using multi-slice detector dual-source CT. Methods A total of 79 patients with heart rate variability higher than 3 beat/min (bpm) were retrospectively analyzed. They were grouped by the scanning methods. Group A (n=40) were performed double turbo flash mode for one-step coronary and carotid-cerebrovascular arteriesinjected with one injection of contrast agent.further divided into Single A (only the phase 1 image)and Double A(combined images of phases 1 and 2). Group B (n=39) were performed separately with twice injection of contrast agent. Subjective scoring was performed on the image quality of the group Single A, Double A and B using a 4-point. Then the objective parameters of image quality, CT attenuations, image noise, signal-to-noise (SNR), and contrast-to-noise (CNR), were evaluated. Then subjective scores, objective evaluation indicators, and radiation dose were compared with one-way ANOVA analysis among the three groups.Contrast agent were compared by using t test in group A and B. Results No significant difference was found (F=2.093, P=0.128) for the subjective scores of the head and neck CTA among the three groups with (3.47±0.51), (3.53±0.51), (3.69±0.47). Significant difference was found (F=50.955, P 0.05), met the requirements for diagnosis; the differences in SNR and CNR of coronary CTA images are statistically significant (F=12.991, 12.236, P 0.05), met the requirements for diagnosis. Radiation dose in the group Double A was lower than group B (decreased by 46.15%,P<0.01).The amount of the contrast agent in the group Double A was lower than group B (decreased by 44.13%, t=-45.455;P<0.01). Conclusion The double turbo flash mode is feasibility for one-step coronary and carotid-cerebrovascular CTA in patients with the heart rate variability using multi-slice dual-source CT.This scan mode can maintain the diagnostic image quality with low contrast agent and radiation dose. Key words: Tomography, X-ray computed; Coronary vessels; Cerebrovascular circulation; Image quality; Radiation dosage; Heart rate
{"title":"Feasibility study of the multi-slice dual-source CT double turbo flash mode for one-step coronary and carotid-cerebrovascular CT angiography in patients with heart rate variability","authors":"Y. Bao, Xiaoying Huang, Zhifei Li, fang-ming Guo, Ming-Zhe Zhao, Kaihong Wang, Shenjie Cao, Yingmin Chen","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.02.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.02.002","url":null,"abstract":"Objective \u0000To investigate the feasibility of one-step coronary and carotid-cerebrovascular computed tomography angiography (CTA) using high-pitch Double Turbo Flash mode and to analyze the image quality and radiation dose in patients with heart rate variability using multi-slice detector dual-source CT. \u0000 \u0000 \u0000Methods \u0000A total of 79 patients with heart rate variability higher than 3 beat/min (bpm) were retrospectively analyzed. They were grouped by the scanning methods. Group A (n=40) were performed double turbo flash mode for one-step coronary and carotid-cerebrovascular arteriesinjected with one injection of contrast agent.further divided into Single A (only the phase 1 image)and Double A(combined images of phases 1 and 2). Group B (n=39) were performed separately with twice injection of contrast agent. Subjective scoring was performed on the image quality of the group Single A, Double A and B using a 4-point. Then the objective parameters of image quality, CT attenuations, image noise, signal-to-noise (SNR), and contrast-to-noise (CNR), were evaluated. Then subjective scores, objective evaluation indicators, and radiation dose were compared with one-way ANOVA analysis among the three groups.Contrast agent were compared by using t test in group A and B. \u0000 \u0000 \u0000Results \u0000No significant difference was found (F=2.093, P=0.128) for the subjective scores of the head and neck CTA among the three groups with (3.47±0.51), (3.53±0.51), (3.69±0.47). Significant difference was found (F=50.955, P 0.05), met the requirements for diagnosis; the differences in SNR and CNR of coronary CTA images are statistically significant (F=12.991, 12.236, P 0.05), met the requirements for diagnosis. Radiation dose in the group Double A was lower than group B (decreased by 46.15%,P<0.01).The amount of the contrast agent in the group Double A was lower than group B (decreased by 44.13%, t=-45.455;P<0.01). \u0000 \u0000 \u0000Conclusion \u0000The double turbo flash mode is feasibility for one-step coronary and carotid-cerebrovascular CTA in patients with the heart rate variability using multi-slice dual-source CT.This scan mode can maintain the diagnostic image quality with low contrast agent and radiation dose. \u0000 \u0000 \u0000Key words: \u0000Tomography, X-ray computed; Coronary vessels; Cerebrovascular circulation; Image quality; Radiation dosage; Heart rate","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43399814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To explore the accurate display method of the local structure of small CT nodules in lung. Methods Close the automatic radiation dose adjustment technique. Keep the thickness of the phantom was 2 mm, the interval between the phantom layers was 2 mm, the pitch was 1, and the reconstructed convoluted nucleus was B80s. Group A controlled the scanning matrix FOV to be 500 mm×500 mm, 400 mm×400 mm, 300 mm×300 mm, 200 mm×200 mm and 100 mm×100 mm, while group B controlled the scanning matrix FOV to be 500 mm×500 mm. Use these parameters to scan the catphan 500 phantom, a routine chest CT conditioned scanning quality control model. The original data raw data were used to reconstruct the FOV to be 400 mm×400 mm, 300 mm×300 mm, 200 mm×200 mm and 100 mm×100 mm under the scanning FOV to be 500 mm×500 mm. All other conditions are consistent. Observe the high contrast resolution module of Catphan 500 phantom, and compare the line logarithms of two groups of images under different scanning FOV or different reconstruction FOV. Thirty-five patients with small pulmonary nodules from February 2018 to March 2018 of the Second Affiliated Hospital of Zhejiang University Medical College were retrospectively collected. The raw data were used to reconstruct the images. The FOV was 320 mm×320 mm in the conventional reconstruction group and 100 mm×100 mm in the local magnification reconstruction group. The subjective score data of the two groups were compared by using rank-sum test. Results When catphan 500 phantom was used, the number of lines in group A and group B increased gradually with the decreasing of FOV. The subjective score of local magnification reconstruction group (4.77±0.35) was higher than that of conventional reconstruction group (3.86±0.50) and the difference was statistically significant (Z=-5.763, P<0.05). Conclusion Local magnification and reconstruction of high-resolution CT images can achieve the same image quality as local magnification, local magnification and reconstruction of image quality is significantly better than simple image magnification. Key words: Tomography,X-ray computed; Radiation dosage; Imaging quality; Comparative study
{"title":"Application of high-resolution CT local augmentation reconstruction to improve the accurate diagnosis of small pulmonary nodule structure","authors":"Xinhong Wang, Jian-zhong Sun, Tingting Hu, Wei-min Zhang","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.02.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.02.006","url":null,"abstract":"Objective \u0000To explore the accurate display method of the local structure of small CT nodules in lung. \u0000 \u0000 \u0000Methods \u0000Close the automatic radiation dose adjustment technique. Keep the thickness of the phantom was 2 mm, the interval between the phantom layers was 2 mm, the pitch was 1, and the reconstructed convoluted nucleus was B80s. Group A controlled the scanning matrix FOV to be 500 mm×500 mm, 400 mm×400 mm, 300 mm×300 mm, 200 mm×200 mm and 100 mm×100 mm, while group B controlled the scanning matrix FOV to be 500 mm×500 mm. Use these parameters to scan the catphan 500 phantom, a routine chest CT conditioned scanning quality control model. The original data raw data were used to reconstruct the FOV to be 400 mm×400 mm, 300 mm×300 mm, 200 mm×200 mm and 100 mm×100 mm under the scanning FOV to be 500 mm×500 mm. All other conditions are consistent. Observe the high contrast resolution module of Catphan 500 phantom, and compare the line logarithms of two groups of images under different scanning FOV or different reconstruction FOV. Thirty-five patients with small pulmonary nodules from February 2018 to March 2018 of the Second Affiliated Hospital of Zhejiang University Medical College were retrospectively collected. The raw data were used to reconstruct the images. The FOV was 320 mm×320 mm in the conventional reconstruction group and 100 mm×100 mm in the local magnification reconstruction group. The subjective score data of the two groups were compared by using rank-sum test. \u0000 \u0000 \u0000Results \u0000When catphan 500 phantom was used, the number of lines in group A and group B increased gradually with the decreasing of FOV. The subjective score of local magnification reconstruction group (4.77±0.35) was higher than that of conventional reconstruction group (3.86±0.50) and the difference was statistically significant (Z=-5.763, P<0.05). \u0000 \u0000 \u0000Conclusion \u0000Local magnification and reconstruction of high-resolution CT images can achieve the same image quality as local magnification, local magnification and reconstruction of image quality is significantly better than simple image magnification. \u0000 \u0000 \u0000Key words: \u0000Tomography,X-ray computed; Radiation dosage; Imaging quality; Comparative study","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46995208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-10DOI: 10.3760/CMA.J.ISSN.1005-1201.2020.0002
Huijing Ma, J. Shao, Yongjiao Wang, A. Zhai, Nannan Zheng, Quan-Kui Li, Yan Liu
Objective@#To investigate the high resolution CT (HRCT) features of novel coronavirus pneumonia (NCP) in children .@*Methods@#A retrospective analysis was performed on the chest HRCT findings of 22 children diagnosed with 2019-nCov pneumonia by clinical and nucleic acid testing in Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology from January 25, 2020 to February 5, 2020. There were 12 boys and 10 girls, aged from 2 months to 14 years old, with a median age of 4 years, and 14 patients were under 5 years old. The characteristics of lung lesions on HRCT imaging such as distribution, shape, density, etc. and whether there were hilar and mediastinal lymph node enlargement and pleural changes were observed by 2 radiologists.@* Results@#In all of the 22 patients, 3 patients (3/22) had normal chest CT, and 19 patients (19/22) had infiltrated lesions in lung. Among them, 7 patients had unilateral lung involvement, 12 patients had bilateral involvement. The HRCT manifestations were as follows. Six patients showed ground glass shadow, including 4 cases showed light ground glass shadow and 2 had typical crazy paving sign. Four patients showed lung consolidation, with localized strip shadow and patchy high-density shadow. Six patients showed patchy lesions with surrounding ground glass shadow, including 1 case with white lung in the right. The bronchopneumonia-like changes in 3 cases, showed scattered spot-like or patchy uneven high-density shadows. The lesions in the lower lobe were more serious than those in the upper lobe, and the lesions in the lateroposterior zone of the lung were more common than those in the apical and central area of the lung. No enlarged lymph nodes and pleural effusion were seen in all patients, and 1 case had thickened interlobar pleura.@*Conclusions@#The HRCT manifestations of NCP in children are diversified, comprehensive judgments need to be made in combination with epidemiological data, clinical manifestations, and laboratory tests, but the chest HRCT can be used as an important basis for early clinical diagnosis and prevention and control interventions.
{"title":"High resolution CT features of novel coronavirus pneumonia in children/ 中华放射学杂志","authors":"Huijing Ma, J. Shao, Yongjiao Wang, A. Zhai, Nannan Zheng, Quan-Kui Li, Yan Liu","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.0002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.0002","url":null,"abstract":"Objective@#To investigate the high resolution CT (HRCT) features of novel coronavirus pneumonia (NCP) in children .@*Methods@#A retrospective analysis was performed on the chest HRCT findings of 22 children diagnosed with 2019-nCov pneumonia by clinical and nucleic acid testing in Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology from January 25, 2020 to February 5, 2020. There were 12 boys and 10 girls, aged from 2 months to 14 years old, with a median age of 4 years, and 14 patients were under 5 years old. The characteristics of lung lesions on HRCT imaging such as distribution, shape, density, etc. and whether there were hilar and mediastinal lymph node enlargement and pleural changes were observed by 2 radiologists.@* Results@#In all of the 22 patients, 3 patients (3/22) had normal chest CT, and 19 patients (19/22) had infiltrated lesions in lung. Among them, 7 patients had unilateral lung involvement, 12 patients had bilateral involvement. The HRCT manifestations were as follows. Six patients showed ground glass shadow, including 4 cases showed light ground glass shadow and 2 had typical crazy paving sign. Four patients showed lung consolidation, with localized strip shadow and patchy high-density shadow. Six patients showed patchy lesions with surrounding ground glass shadow, including 1 case with white lung in the right. The bronchopneumonia-like changes in 3 cases, showed scattered spot-like or patchy uneven high-density shadows. The lesions in the lower lobe were more serious than those in the upper lobe, and the lesions in the lateroposterior zone of the lung were more common than those in the apical and central area of the lung. No enlarged lymph nodes and pleural effusion were seen in all patients, and 1 case had thickened interlobar pleura.@*Conclusions@#The HRCT manifestations of NCP in children are diversified, comprehensive judgments need to be made in combination with epidemiological data, clinical manifestations, and laboratory tests, but the chest HRCT can be used as an important basis for early clinical diagnosis and prevention and control interventions.","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44035380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-10DOI: 10.3760/CMA.J.ISSN.1005-1201.2020.02.004
T. Kang, Yunfu Liu, Dandan Liu, Lili Zhang, Y. Niu
Objective To investigate the relationship between current-exposure time products (mAs) and image quality in digital mammography. Methods The CDMAM phantom of 2 to 7 cm thickness were exposed by manual exposure modes using Mo-Rh anode-filer combinations. The exposure parameters were set as follows: (2 cm, 27 kVp, 10 to 90 mAs); (3 cm, 29 kVp, 20 to 120 mAs); (4 cm, 29 kVp, 20 to 200 mAs); (5 cm, 30 kVp, 40 to 220 mAs); (6 cm, 31 kVp, 40 to 260 mAs); (7 cm, 32 kVp, 80 to 280 mAs). The image quality figure (IQF), contrast to noise ratio (CNR), figure of merit (FOM) and the average glandular dose (AGD) were obtained from images. The optimum filtration and kVp for each breast thickness was found from the calculated FOMs. The optimum mAs for each breast thickness were found from the calculated FOMs and IQFs. And the Pearson correlation analysis was used to analyze the correlations among AGD, CNR and IQF. Results With the increase of mAs, the average glandular dose were linearly increased, and the FOM first increased and then decreased or changed slowly. The AGD, CNR and IQF were significantly correlated when the compression thickness was less than 7 cm (r all>0.87, P<0.05). The optimized exposure parameters were list as follows (2 cm,27 kVp,20 to 30 mAs);(3 cm,29 kVp,30 to 50 mAs); (4 cm,29 kVp,80 to 100 mAs); (5 cm, 30 kVp, 80 to 120 mAs); (6 cm, 31 kVp, 100 to 140 mAs); (7 cm, 32 kVp, 80 to 120 mAs). Conclusion The optimum range of mAs can be confirmed with different breast compression thickness and the setting of automatic exposure parameters should be chosen in clinical practice. Key words: Mammography; Image quality; Radiation dosage
目的探讨数字乳房x线摄影中电流暴露时间积(mAs)与图像质量的关系。方法采用Mo-Rh阳极-滤镜组合的手工曝光方式对厚度为2 ~ 7cm的CDMAM模体进行曝光。暴露参数设置为:(2 cm, 27 kVp, 10 ~ 90 ma);(3 cm, 29 kVp, 20 ~ 120 ma);(4 cm, 29 kVp, 20 ~ 200 ma);(5 cm, 30 kVp, 40 ~ 220 ma);(6 cm, 31 kVp, 40 ~ 260 ma);(7 cm, 32 kVp, 80 ~ 280 ma)。从图像中得到图像质量图(IQF)、噪声对比比(CNR)、优值图(FOM)和平均腺剂量(AGD)。通过计算得到各乳房厚度的最佳滤过率和kVp。根据计算的fom和iqf，找到了各乳房厚度的最佳ma。采用Pearson相关分析分析AGD、CNR和IQF之间的相关性。结果随着ma的增加，平均腺剂量呈线性增加，FOM先升高后降低或变化缓慢。压缩厚度小于7 cm时，AGD、CNR和IQF呈显著相关(r均为0.87,P<0.05)。优化后的暴露参数为(2 cm,27 kVp,20 ~ 30 ma);(3 cm,29 kVp,30 ~ 50 ma);(4 cm,29 kVp,80 ~ 100 ma);(5 cm, 30 kVp, 80 ~ 120 ma);(6 cm, 31 kVp, 100 ~ 140 ma);(7 cm, 32 kVp, 80至120 ma)。结论不同的乳房压迫厚度可确定mAs的最佳范围，临床应选择自动曝光参数的设置。关键词:乳房x线摄影;图像质量;辐射剂量
{"title":"A study for tube current exposure time products and image quality in digital mammography","authors":"T. Kang, Yunfu Liu, Dandan Liu, Lili Zhang, Y. Niu","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.02.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.02.004","url":null,"abstract":"Objective \u0000To investigate the relationship between current-exposure time products (mAs) and image quality in digital mammography. \u0000 \u0000 \u0000Methods \u0000The CDMAM phantom of 2 to 7 cm thickness were exposed by manual exposure modes using Mo-Rh anode-filer combinations. The exposure parameters were set as follows: (2 cm, 27 kVp, 10 to 90 mAs); (3 cm, 29 kVp, 20 to 120 mAs); (4 cm, 29 kVp, 20 to 200 mAs); (5 cm, 30 kVp, 40 to 220 mAs); (6 cm, 31 kVp, 40 to 260 mAs); (7 cm, 32 kVp, 80 to 280 mAs). The image quality figure (IQF), contrast to noise ratio (CNR), figure of merit (FOM) and the average glandular dose (AGD) were obtained from images. The optimum filtration and kVp for each breast thickness was found from the calculated FOMs. The optimum mAs for each breast thickness were found from the calculated FOMs and IQFs. And the Pearson correlation analysis was used to analyze the correlations among AGD, CNR and IQF. \u0000 \u0000 \u0000Results \u0000With the increase of mAs, the average glandular dose were linearly increased, and the FOM first increased and then decreased or changed slowly. The AGD, CNR and IQF were significantly correlated when the compression thickness was less than 7 cm (r all>0.87, P<0.05). The optimized exposure parameters were list as follows (2 cm,27 kVp,20 to 30 mAs);(3 cm,29 kVp,30 to 50 mAs); (4 cm,29 kVp,80 to 100 mAs); (5 cm, 30 kVp, 80 to 120 mAs); (6 cm, 31 kVp, 100 to 140 mAs); (7 cm, 32 kVp, 80 to 120 mAs). \u0000 \u0000 \u0000Conclusion \u0000The optimum range of mAs can be confirmed with different breast compression thickness and the setting of automatic exposure parameters should be chosen in clinical practice. \u0000 \u0000 \u0000Key words: \u0000Mammography; Image quality; Radiation dosage","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43830867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In recent years, with the promotion of national fitness, running has become one of the most popular sports, especially marathon. At the same time, people's attention to running injuries is also increasing, especially in the knee and ankle joints. Joint cartilage, as a component of joints, can cause joint degeneration and a series of joint diseases once damaged. MRI, as a non-invasive examination, can reflect the early biochemical changes of cartilage before the appearance of morphological changes, and has important value for early diagnosis of cartilage lesions. Currently, quantitative MRI techniques for cartilage mainly include T1 ρ、 T2 mapping, T2 * mapping, etc. The author reviews the progress of MRI quantitative research on the changes in articular cartilage caused by running.
{"title":"Research progress of quantitative MRI in running-related articular cartilage changes","authors":"Yanjing Zhang, Li Zhang, Jianping Ding","doi":"10.3760/CMA.J.ISSN.1005-1201.2020.02.019","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-1201.2020.02.019","url":null,"abstract":"近年来，随着全民健身的倡导，跑步越来越成为最受欢迎的体育运动之一，尤其是马拉松运动。同时人们对跑步运动损伤的关注度也越来越高，特别是膝关节及踝关节。关节软骨作为关节组成部分，一旦发生损伤，会导致关节退变及一系列的关节病变。MRI作为一项无创性检查，能够反映软骨在形态学改变出现前的早期生化成分改变，对早期诊断软骨病变有着重要价值。目前软骨的定量MRI技术主要包括T1ρ、T2 mapping、T2* mapping等。笔者就跑步引起关节软骨改变的MRI定量研究进展进行综述。","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42203666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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