Pub Date : 2021-06-10DOI: 10.3760/CMA.J.CN112149-20200614-00813
D. Guo, Kong Linghua, W. Bai, Yingkun He, Tianxiao Li, Yanyan He, Ajmal Zemmar, B. Nelson
{"title":"Study progress of cerebrovascular interventional surgery robot","authors":"D. Guo, Kong Linghua, W. Bai, Yingkun He, Tianxiao Li, Yanyan He, Ajmal Zemmar, B. Nelson","doi":"10.3760/CMA.J.CN112149-20200614-00813","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112149-20200614-00813","url":null,"abstract":"","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48704184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-10DOI: 10.3760/CMA.J.CN112149-20200218-00187
Zhiqing Deng, Xiaochun Zhang, Yirong Li, Haibo Xu, Yadong Gang, Han-lun Wang, Rufang Liao, Ying-hui Jin, Xing-huan Wang, Xian-Tao Zeng, S. Luo, Z. Pan
Objective In view of the difficulty of the shortage of new coronavirus nucleal acid test in the early COVID-19 outbreak, to explore the application value of chest CT in screening COVID-19 patients. Methods Retrospective analysis was performed on the data of patients with fever who received chest CT and new coronavirus nucleal acid test during January 25, 2020 to February 2, 2020 in Zhongnan Hospital of Wuhan University. A total of 587 patients were enrolled, including 290 males and 297 females, aged from 11.0 to 96.0 (51.3±17.1) years old. Take the nucleic acid test results as the gold standard, the sensitivity, specificity and rate of missed diagnosis of CT screening COVID-19 were calculated. Results Among the 587 patients, there were 433 positive cases (73.8%, 433/587) and 154 negative cases (26.2%, 154/587) of novel coronavirus nucleic acid test. Using CT screening, 494 cases (84.2%, 494/587) were positive and 93 cases (15.8%, 93/587) were negative. The sensitivity of CT screening COVID-19 was 97.7% (423/433), specificity was 53.9% (83/154) and rate of missed diagnosis was 2.3% (10/433). Conclusions In the early COVID-19 outbreak, CT screening has the advantages of high sensitivity and low rate of missed diagnosis of COVID-19, which can compensate for the shortage of new coronavirus nucleal acid test and can be used as the basis for rapid screening for early prevention and control of COVID-19 outbreak. Key words: COVID-19; Tomography, X-ray computed; Diagnostic test; Sensitivity
{"title":"Value of chest CT screening in the early COVID-19 outbreak","authors":"Zhiqing Deng, Xiaochun Zhang, Yirong Li, Haibo Xu, Yadong Gang, Han-lun Wang, Rufang Liao, Ying-hui Jin, Xing-huan Wang, Xian-Tao Zeng, S. Luo, Z. Pan","doi":"10.3760/CMA.J.CN112149-20200218-00187","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112149-20200218-00187","url":null,"abstract":"Objective \u0000In view of the difficulty of the shortage of new coronavirus nucleal acid test in the early COVID-19 outbreak, to explore the application value of chest CT in screening COVID-19 patients. \u0000 \u0000 \u0000Methods \u0000Retrospective analysis was performed on the data of patients with fever who received chest CT and new coronavirus nucleal acid test during January 25, 2020 to February 2, 2020 in Zhongnan Hospital of Wuhan University. A total of 587 patients were enrolled, including 290 males and 297 females, aged from 11.0 to 96.0 (51.3±17.1) years old. Take the nucleic acid test results as the gold standard, the sensitivity, specificity and rate of missed diagnosis of CT screening COVID-19 were calculated. \u0000 \u0000 \u0000Results \u0000Among the 587 patients, there were 433 positive cases (73.8%, 433/587) and 154 negative cases (26.2%, 154/587) of novel coronavirus nucleic acid test. Using CT screening, 494 cases (84.2%, 494/587) were positive and 93 cases (15.8%, 93/587) were negative. The sensitivity of CT screening COVID-19 was 97.7% (423/433), specificity was 53.9% (83/154) and rate of missed diagnosis was 2.3% (10/433). \u0000 \u0000 \u0000Conclusions \u0000In the early COVID-19 outbreak, CT screening has the advantages of high sensitivity and low rate of missed diagnosis of COVID-19, which can compensate for the shortage of new coronavirus nucleal acid test and can be used as the basis for rapid screening for early prevention and control of COVID-19 outbreak. \u0000 \u0000 \u0000Key words: \u0000COVID-19; Tomography, X-ray computed; Diagnostic test; Sensitivity","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41679528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-10DOI: 10.3760/CMA.J.CN112149-20200218-00189
Xiaohu Li, Haitao Wang, Juan Zhu, Xiaohui Qiu, Jinping Zhang, Guoquan Huang, Xiaosong Zeng, K. He, Zongyu Xie, Qizhong Xu, Bin Liu, Yongqiang Yu
Objective: To explore the imaging changes of lung lesions in patients with imported COVID-19 when reaching the discharge standard. Methods: The clinical and CT imaging data of 60 cured patients with imported COVID-19 and discharged from January to February 2020 in Anhui Province were retrospectively collected. At the initial diagnosis, 5 cases were mild, 53 were ordinary, and 2 were severe. The clinical characteristics of the patients and the characteristics of chest CT images at discharge were analyzed. Results: Fever (57 cases) and cough (55 cases) were the main symptoms in 60 patients. In 5 mild patients, 3 cases were negative in the whole course of CT examination, 2 cases were negative in the first time and abnormal in the second time. The first CT imaging features of 55 patients (53 common type and 2 severe type) were mainly bilateral lung involvement (51 cases), multiple lesions (33 cases), more common under the pleura (40 cases), and ground glass opacities were the most common (55 cases). The features of chest CT in clinical outcomes were that the ground glass shadow in the lung gradually faded and was completely absorbed (19 cases); the scope of ground glass shadow in the lung expanded and progressed to crazy-paving, consolidation shadow, and the lesion gradually absorbed again followed by fibrous cord shadows (27 cases); ground-glass opacities in the lungs quickly progressed to a consolidation and then slowly absorbed. Most of the lesions were accompanied by more residual fibrous cord shadows (4 cases). In 2 severe patients, the lesions in the lungs were larger ground glass, and a large amount of fibrous foci remained after slow absorption. Conclusions: Chest CT plays an important role in the diagnosis and treatment of imported COVID-19, and the degree of lung involvement seen on CT images is in good agreement with clinical outcome.
{"title":"Imaging dynamic observation of cured COVID-19 patients with imported coronavirus pneumonia/ 输入性新型冠状病毒肺炎治愈患者肺内病变的影像学动态观察","authors":"Xiaohu Li, Haitao Wang, Juan Zhu, Xiaohui Qiu, Jinping Zhang, Guoquan Huang, Xiaosong Zeng, K. He, Zongyu Xie, Qizhong Xu, Bin Liu, Yongqiang Yu","doi":"10.3760/CMA.J.CN112149-20200218-00189","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112149-20200218-00189","url":null,"abstract":"Objective: To explore the imaging changes of lung lesions in patients with imported COVID-19 when reaching the discharge standard. Methods: The clinical and CT imaging data of 60 cured patients with imported COVID-19 and discharged from January to February 2020 in Anhui Province were retrospectively collected. At the initial diagnosis, 5 cases were mild, 53 were ordinary, and 2 were severe. The clinical characteristics of the patients and the characteristics of chest CT images at discharge were analyzed. Results: Fever (57 cases) and cough (55 cases) were the main symptoms in 60 patients. In 5 mild patients, 3 cases were negative in the whole course of CT examination, 2 cases were negative in the first time and abnormal in the second time. The first CT imaging features of 55 patients (53 common type and 2 severe type) were mainly bilateral lung involvement (51 cases), multiple lesions (33 cases), more common under the pleura (40 cases), and ground glass opacities were the most common (55 cases). The features of chest CT in clinical outcomes were that the ground glass shadow in the lung gradually faded and was completely absorbed (19 cases); the scope of ground glass shadow in the lung expanded and progressed to crazy-paving, consolidation shadow, and the lesion gradually absorbed again followed by fibrous cord shadows (27 cases); ground-glass opacities in the lungs quickly progressed to a consolidation and then slowly absorbed. Most of the lesions were accompanied by more residual fibrous cord shadows (4 cases). In 2 severe patients, the lesions in the lungs were larger ground glass, and a large amount of fibrous foci remained after slow absorption. Conclusions: Chest CT plays an important role in the diagnosis and treatment of imported COVID-19, and the degree of lung involvement seen on CT images is in good agreement with clinical outcome.","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44375865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To explore the diagnostic value of chest CT imaging in differential diagnosis between common-type COVID-19 and mycoplasma pneumonia (MP). Methods: From the January to February 2020, the clinical and imaging data of COVID-19 patients (diagnosed in the Affiliated Hospital of Jining Medical University, the Fourth People's Hospital of Jining and the Second People's Hospital of Jining) and MP patients (diagnosed in the Affiliated Hospital of Jining Medical University) were retrospectively collected and analyzed. Forty-three patients with common-type COVID-19 (28 males, 15 females, 43±14 years old) and 50 patients with MP (19 males, 31 females, 37±14 years old) were enrolled as COVID-19 group and MP group, respectively. The clinical manifestations, laboratory results and chest CT findings of these two groups were analyzed and compared. Results: (1) Clinical manifestations: there were more patients with muscle ache and asthenia in COVID-19 group than in MP group (χ ²=5.110, 4.834, P 0.05). (2) Laboratory examination: the procalcitonin level of cases in COVID-19 group was significantly lower than that in MP group (χ ²=12.263, P=0.001). No significant difference was found in leukocyte count, lymphocyte count, C-reactive protein level and erythrocyte sedimentation rate (Z=-1.117, χ ²=2.410, 0.787, 0.800, all P>0.05) between two groups. (3) Chest CT findings bilateral lung involvement was found more in COVID-19 group than in MP group (χ ²=30.012, P 0.05). Ground glass, paving stone sign and air bronchus sign were found significantly more in COVID-19 group than in MP group (χ ²=30.171, 19.119, 9.790, all P<0.05); while the pulmonary consolidation, central lobular nodule and centripetal thickening of bronchus wall were found significantly less in COVID-19 group than in MP group (χ ²=25.450, 33.532, 48.553, all P<0.001). Conclusions: The clinical manifestations and laboratory examination have limited value in the differential diagnosis of common-type COVID-19 and MP, while chest CT imaging might be more valuable in the early differential diagnosis of these two diseases.
{"title":"The diagnostic value of chest CT imaging in differential diagnosis between common-type COVID-19 and mycoplasma pneumonia/ 胸部CT在普通型新型冠状病毒肺炎与支原体肺炎鉴别诊断中的价值","authors":"Zhanguo Sun, Zhengtong Wang, Yueqin Chen, W. Qin, Wen-feng Zhao, Wei Liu, Zhongsheng Zhang","doi":"10.3760/CMA.J.CN112149-20200310-00371","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112149-20200310-00371","url":null,"abstract":"Objective: To explore the diagnostic value of chest CT imaging in differential diagnosis between common-type COVID-19 and mycoplasma pneumonia (MP). Methods: From the January to February 2020, the clinical and imaging data of COVID-19 patients (diagnosed in the Affiliated Hospital of Jining Medical University, the Fourth People's Hospital of Jining and the Second People's Hospital of Jining) and MP patients (diagnosed in the Affiliated Hospital of Jining Medical University) were retrospectively collected and analyzed. Forty-three patients with common-type COVID-19 (28 males, 15 females, 43±14 years old) and 50 patients with MP (19 males, 31 females, 37±14 years old) were enrolled as COVID-19 group and MP group, respectively. The clinical manifestations, laboratory results and chest CT findings of these two groups were analyzed and compared. Results: (1) Clinical manifestations: there were more patients with muscle ache and asthenia in COVID-19 group than in MP group (χ ²=5.110, 4.834, P 0.05). (2) Laboratory examination: the procalcitonin level of cases in COVID-19 group was significantly lower than that in MP group (χ ²=12.263, P=0.001). No significant difference was found in leukocyte count, lymphocyte count, C-reactive protein level and erythrocyte sedimentation rate (Z=-1.117, χ ²=2.410, 0.787, 0.800, all P>0.05) between two groups. (3) Chest CT findings bilateral lung involvement was found more in COVID-19 group than in MP group (χ ²=30.012, P 0.05). Ground glass, paving stone sign and air bronchus sign were found significantly more in COVID-19 group than in MP group (χ ²=30.171, 19.119, 9.790, all P<0.05); while the pulmonary consolidation, central lobular nodule and centripetal thickening of bronchus wall were found significantly less in COVID-19 group than in MP group (χ ²=25.450, 33.532, 48.553, all P<0.001). Conclusions: The clinical manifestations and laboratory examination have limited value in the differential diagnosis of common-type COVID-19 and MP, while chest CT imaging might be more valuable in the early differential diagnosis of these two diseases.","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49213621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-10DOI: 10.3760/CMA.J.CN112149-20190421-00026
Zhipeng Liu, Ying-cai Sun, Haofei Cui, J. Cui, Wei Zhang
前瞻性纳入2017年12月至2018年9月河北医科大学第三医院经临床及MRI确诊，并接受经皮椎间孔镜下髓核摘除术（PTED）治疗的19例腰椎间盘单侧侧后方突出患者，于术前1 d，术后3、30、90 d行腰5(L5）、骶1(S1）神经根扩散张量成像（DTI）。由2名放射科医师于L5、S1患侧神经近、中、远节段及同节段健侧相应部位以"播点"法勾画感兴趣区（ROI ），测量DTI参数各向异性分数（FA）和表观扩散系数（ADC）值，计算每侧神经3个ROI的平均值。采用配对t检验比较患侧与健侧神经DTI参数的差异，手术前后DTI参数的比较采用单因素方差分析或Kruskal-Wallis H检验。结果显示：（1）术前1 d L5神经患侧和健侧FA值分别为0.35±0.03、0.45±0.01, S1患侧和健侧分别为0.36±0.02、0.46±0.02，L5、S1患侧神经根FA值低于健侧（t=-10.188、-37.683，P均 0.05）。表明DTI可用于定量评估腰骶神经PTED术后修复状况。
Prospective inclusion of 19 patients with unilateral posterior lumbar disc herniation who were diagnosed clinically and MRI at the Third Hospital of Hebei Medical University from December 2017 to September 2018 and underwent percutaneous transforaminal nucleus pulposectomy (PTED) treatment. Diffusion tensor imaging (DTI) of the L5 and S1 nerve roots was performed 1 day before surgery and 3, 30, and 90 days after surgery. Two radiologists delineated the region of interest (ROI) using the "seeding point" method at the proximal, middle, and distal segments of the affected nerves in L5 and S1, as well as the corresponding areas on the healthy side of the same segment. The anisotropy score (FA) and apparent diffusion coefficient (ADC) values of the DTI parameters were measured, and the average of three ROIs on each side of the nerves was calculated. Paired t-tests were used to compare the differences in DTI parameters between the affected and healthy sides of the nerve. The comparison of DTI parameters before and after surgery was performed using one-way ANOVA or Kruskal Wallis H-test. The results showed that: (1) On the 1st day before surgery, the FA values of the affected and healthy sides of the L5 nerve were 0.35 ± 0.03 and 0.45 ± 0.01, respectively. The FA values of the affected and healthy sides of the S1 nerve were 0.36 ± 0.02 and 0.46 ± 0.02, respectively. The FA values of the nerve roots on the L5 and S1 affected sides were lower than those on the healthy side (t=-10.188 and -37.683, both P=0.05). This indicates that DTI can be used to quantitatively evaluate the postoperative repair status of lumbar sacral nerve PTED.
{"title":"Feasibility of diffusion tensor imaging quantitative analysis in evaluation of nerve repair after minimally invasive surgery for lumbar disc herniation","authors":"Zhipeng Liu, Ying-cai Sun, Haofei Cui, J. Cui, Wei Zhang","doi":"10.3760/CMA.J.CN112149-20190421-00026","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112149-20190421-00026","url":null,"abstract":"前瞻性纳入2017年12月至2018年9月河北医科大学第三医院经临床及MRI确诊，并接受经皮椎间孔镜下髓核摘除术（PTED）治疗的19例腰椎间盘单侧侧后方突出患者，于术前1 d，术后3、30、90 d行腰5(L5）、骶1(S1）神经根扩散张量成像（DTI）。由2名放射科医师于L5、S1患侧神经近、中、远节段及同节段健侧相应部位以\"播点\"法勾画感兴趣区（ROI ），测量DTI参数各向异性分数（FA）和表观扩散系数（ADC）值，计算每侧神经3个ROI的平均值。采用配对t检验比较患侧与健侧神经DTI参数的差异，手术前后DTI参数的比较采用单因素方差分析或Kruskal-Wallis H检验。结果显示：（1）术前1 d L5神经患侧和健侧FA值分别为0.35±0.03、0.45±0.01, S1患侧和健侧分别为0.36±0.02、0.46±0.02，L5、S1患侧神经根FA值低于健侧（t=-10.188、-37.683，P均 0.05）。表明DTI可用于定量评估腰骶神经PTED术后修复状况。","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42689121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-10DOI: 10.3760/CMA.J.CN112149-20200206-00100
Huijing Ma, J. Shao, Yongjiao Wang, A. Zhai, Nannan Zheng, Quan-Kui Li, Yan Liu
Objective: To investigate the high resolution CT (HRCT) features of COVID-19 in children. Methods: A retrospective analysis was performed on the chest HRCT findings of 22 children who were diagnosed as COVID-19 by clinical and nucleic acid testing in Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology from January 25 to February 5, 2020. There were 12 boys and 10 girls, aged from 2 months to 14 years old, with a median age of 4 years, and 14 patients were under 5 years old. The characteristics of lung lesions on HRCT such as distribution, shape, density and so on and whether there were hilar and mediastinal lymph node enlargement and pleural changes were evaluated by 2 radiologists. Results: In all of the 22 patients, the chest CT manifestations were normal in 3 patients (3/22), meanwhile the lung involvement of the lesion was found in 19 patients (19/22). Among them, 7 patients had unilateral lung involvement, and 12 patients had bilateral involvement. The HRCT manifestations were as follows. The HRCT showed the ground glass opacity (GGO) in 6 patients, including 4 cases with light opacity and 2 with typical crazy paving sign. Four patients had lung consolidation, with local fibrous stripes and patchy hyperdensity. Six patients had mixed GGO, including 1 case with right white lung. The bronchopneumonia-like changes were seen in 3 cases with scattered spot-like or mixed patchy. The lesions in the lower lobe were more serious than those in the upper lobe, and the lesions in the lateroposterior zone of the lung were more common than those in the apical and central area of the lung. No enlarged lymph nodes and pleural effusion were seen in all patients, but 1 case had thickened interlobar pleura. Conclusions: The HRCT manifestations of COVID-19 in children are varied, and the comprehensive assessment need to be made in combination with epidemiological data, clinical manifestations and laboratory tests. However, the chest HRCT plays an important role in early diagnosis, prevention and management of COVID-19.
{"title":"High resolution CT features of COVID-19 in children/ 新型冠状病毒肺炎儿童高分辨率CT表现","authors":"Huijing Ma, J. Shao, Yongjiao Wang, A. Zhai, Nannan Zheng, Quan-Kui Li, Yan Liu","doi":"10.3760/CMA.J.CN112149-20200206-00100","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112149-20200206-00100","url":null,"abstract":"Objective: To investigate the high resolution CT (HRCT) features of COVID-19 in children. Methods: A retrospective analysis was performed on the chest HRCT findings of 22 children who were diagnosed as COVID-19 by clinical and nucleic acid testing in Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology from January 25 to February 5, 2020. There were 12 boys and 10 girls, aged from 2 months to 14 years old, with a median age of 4 years, and 14 patients were under 5 years old. The characteristics of lung lesions on HRCT such as distribution, shape, density and so on and whether there were hilar and mediastinal lymph node enlargement and pleural changes were evaluated by 2 radiologists. Results: In all of the 22 patients, the chest CT manifestations were normal in 3 patients (3/22), meanwhile the lung involvement of the lesion was found in 19 patients (19/22). Among them, 7 patients had unilateral lung involvement, and 12 patients had bilateral involvement. The HRCT manifestations were as follows. The HRCT showed the ground glass opacity (GGO) in 6 patients, including 4 cases with light opacity and 2 with typical crazy paving sign. Four patients had lung consolidation, with local fibrous stripes and patchy hyperdensity. Six patients had mixed GGO, including 1 case with right white lung. The bronchopneumonia-like changes were seen in 3 cases with scattered spot-like or mixed patchy. The lesions in the lower lobe were more serious than those in the upper lobe, and the lesions in the lateroposterior zone of the lung were more common than those in the apical and central area of the lung. No enlarged lymph nodes and pleural effusion were seen in all patients, but 1 case had thickened interlobar pleura. Conclusions: The HRCT manifestations of COVID-19 in children are varied, and the comprehensive assessment need to be made in combination with epidemiological data, clinical manifestations and laboratory tests. However, the chest HRCT plays an important role in early diagnosis, prevention and management of COVID-19.","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46480800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"China interpretation of prostate imaging-reporting and data system (PI-RADS V2.1) guideline for prostate cancer management","authors":"Liang Wang, Qiubai Li, H. Vargas","doi":"10.3760/CMA.J.CN112149-20190429-00382","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112149-20190429-00382","url":null,"abstract":"2019年前列腺成像报告和数据系统（PI-RADS）指导委员会发表了PI-RADS V2.1。许多研究已经揭示了2015年发布的PI-RADS V2的价值和局限性。PI-RADS V2.1对V2技术规范和评分标准的局限性进行了修改。笔者对VI-RADS V2.1的要点进行解读。","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44208679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To investigate the value of whole-lesion histogram parameters of apparent diffusion coefficient (ADC) in evaluating and predicting the pathological complete response(PCR) to neoadjuvant chemotherapy (NAC) in different subtypes of breast cancer. Methods This retrospective study included 117 patients with breast cancer who underwent MRI examination before NAC prior to surgery from January 2016 to December 2017 in the First Affiliated Hospital of Nanjing University. All cases were divided into Luminal B, HER2 positive (n=21) and triple negative (n=26) groups. The surgical pathology after chemotherapy was evaluated by Miller-Payne (M-P) system and the patients were divided into PCR group and non-PCR (nPCR) group. Firevoxel software was used to generate the whole-lesion ADC histogram. The parameters included mean (ADCmean), skewness, kurtosis, the minimum (ADCmin), the maximum (ADCmax), 10th percentile(ADC10%), 50th percentile (ADC50%) and 90th percentile (ADC90%). The two independent samples t test or Mann-Whitney U test was used to compare the differences between PCR and nPCR groups in each subtype. The diagnostic performance of statistically different ADC parameters for predicting PCR was evaluated by receiver operating characteristic (ROC) curve. Results Kurtosis was significantly higher in PCR group than that in nPCR group in HER2 positive subtype (P=0.039). It achieved an area under the curve (AUC) of 0.813 with sensitivity of 100% and specificity of 68.7% at the optimal cutoff value (1.861) for differentiating PCR from nPCR cases. In triple negative subtype, ADCmean and ADC50% were smaller in PCR group than those in nPCR group (P=0.028,0.013). They achieved AUCs of 0.800, 0.842, respectively. When ADCmean of 1.030×10-3 mm2/s and ADC50% of 0.976×10-3 mm2/s were used as cutoff value to differentiate PCR from nPCR, the sensitivities were 75.0%, 80.0% and the specificities were 83.3%, 83.3%, respectively. Conclusion Kurtosis can predict post-NAC PCR in patients with HER2 positive breast cancer, while ADC50% has a high value in predicting post NAC PCR of triple negative breast cancer patients. Key words: Breast neoplasms; Molecular subtype; Neoadjuvant chemotherapy; Magnetic resonance imaging
{"title":"Whole-lesion histogram analysis of apparent diffusion coefficient for the prediction of pathological complete response to neoadjuvant chemotherapy in different subtypes of breast cancer","authors":"Xiao Wang, Liyu Zhu, X. Zha, Hong-Li Liu, Si-qi Wang, Jianjuan Lou, Qi-Gui Zou, Cong Wang, Jue Wang, Yanni Jiang","doi":"10.3760/CMA.J.CN112149-20190522-00439","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112149-20190522-00439","url":null,"abstract":"Objective \u0000To investigate the value of whole-lesion histogram parameters of apparent diffusion coefficient (ADC) in evaluating and predicting the pathological complete response(PCR) to neoadjuvant chemotherapy (NAC) in different subtypes of breast cancer. \u0000 \u0000 \u0000Methods \u0000This retrospective study included 117 patients with breast cancer who underwent MRI examination before NAC prior to surgery from January 2016 to December 2017 in the First Affiliated Hospital of Nanjing University. All cases were divided into Luminal B, HER2 positive (n=21) and triple negative (n=26) groups. The surgical pathology after chemotherapy was evaluated by Miller-Payne (M-P) system and the patients were divided into PCR group and non-PCR (nPCR) group. Firevoxel software was used to generate the whole-lesion ADC histogram. The parameters included mean (ADCmean), skewness, kurtosis, the minimum (ADCmin), the maximum (ADCmax), 10th percentile(ADC10%), 50th percentile (ADC50%) and 90th percentile (ADC90%). The two independent samples t test or Mann-Whitney U test was used to compare the differences between PCR and nPCR groups in each subtype. The diagnostic performance of statistically different ADC parameters for predicting PCR was evaluated by receiver operating characteristic (ROC) curve. \u0000 \u0000 \u0000Results \u0000Kurtosis was significantly higher in PCR group than that in nPCR group in HER2 positive subtype (P=0.039). It achieved an area under the curve (AUC) of 0.813 with sensitivity of 100% and specificity of 68.7% at the optimal cutoff value (1.861) for differentiating PCR from nPCR cases. In triple negative subtype, ADCmean and ADC50% were smaller in PCR group than those in nPCR group (P=0.028,0.013). They achieved AUCs of 0.800, 0.842, respectively. When ADCmean of 1.030×10-3 mm2/s and ADC50% of 0.976×10-3 mm2/s were used as cutoff value to differentiate PCR from nPCR, the sensitivities were 75.0%, 80.0% and the specificities were 83.3%, 83.3%, respectively. \u0000 \u0000 \u0000Conclusion \u0000Kurtosis can predict post-NAC PCR in patients with HER2 positive breast cancer, while ADC50% has a high value in predicting post NAC PCR of triple negative breast cancer patients. \u0000 \u0000 \u0000Key words: \u0000Breast neoplasms; Molecular subtype; Neoadjuvant chemotherapy; Magnetic resonance imaging","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44975943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CT findings and location characteristics of the intraperitoneal bronchogenic cyst","authors":"Fan Zhang, Wenhao Fu, Yang Peng, Huanjun J Wang, J. Guan","doi":"10.3760/CMA.J.CN112149-20190424-00110","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112149-20190424-00110","url":null,"abstract":"回顾性分析2001年1月至2017年12月中山大学附属第一医院经手术病理证实的14例腹腔异位支气管囊肿患者资料，探讨腹腔异位支气管囊肿的影像学表现。14例均表现为边界清晰的圆形或卵圆形薄壁单囊状病灶。12例CT平扫呈均匀较高密度，2例呈稍低密度，增强扫描均无强化。囊壁钙化3例。2例在T1WI呈稍高信号，T2WI呈高信号。病灶定位左侧腹腔较右侧腹腔常见，腹膜后肾上腺区最常见。肾上腺区病灶具有与膈肌关系密切的特点。腹腔异位支气管囊肿CT表现具有一定特征，结合发病部位，有助于准确诊断。","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41365971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The development of intracranial vascular wall MRI imaging technology is rapid, which can achieve high-resolution imaging of various intracranial arterial wall lesions. This not only significantly improves the imaging diagnosis and differential diagnosis ability, but also helps in the prevention, risk stratification, and formulation of treatment plans for cerebrovascular diseases. High resolution MR vascular wall imaging technology has obvious advantages and application prospects in the diagnosis and treatment of intracranial arterial lesions.
{"title":"Attaching importance to the research of vessel wall MRI in cerebrovascular disorders","authors":"Jun Zhang, Lin Ma","doi":"10.3760/CMA.J.CN112149-20200207-00109","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112149-20200207-00109","url":null,"abstract":"颅内血管壁MRI成像技术发展迅速，能够实现对多种颅内动脉管壁病变的高分辨率成像，不仅明显提升了影像诊断及鉴别诊断能力，还有助于脑血管病的预防、危险分层及制定治疗方案，高分辨率MR管壁成像技术在颅内动脉病变的诊疗中具有明显的优势和应用前景。","PeriodicalId":39377,"journal":{"name":"Zhonghua fang she xue za zhi Chinese journal of radiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47572135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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