Precision medicine offers the potential to improve health through deeper understandings of the lifestyle, biological, and environmental influences on health. Under Dr. Donald A. B. Lindberg’s leadership, the U.S. National Library of Medicine (NLM) has developed the central reference resources for biomedical research and molecular laboratory medicine that enable precision medicine. The hosting and curation of biomedical knowledge repositories and data by NLM enable quality information reachable for providers and researchers throughout the world. NLM has been supporting the innovation of electronic health record systems to implement computability and secondary use for biomedical research, producing the scale of linked health and molecular datasets necessary for precision medicine discovery.
精准医学通过深入了解生活方式、生物和环境对健康的影响，提供了改善健康的潜力。在Donald A. B. Lindberg博士的领导下，美国国家医学图书馆(NLM)开发了生物医学研究和分子实验室医学的中心参考资源，使精准医学成为可能。NLM对生物医学知识库和数据的托管和管理使世界各地的提供者和研究人员能够获得高质量的信息。NLM一直在支持电子健康记录系统的创新，以实现生物医学研究的可计算性和二次使用，产生精确医学发现所需的链接健康和分子数据集的规模。
{"title":"The U.S. National Library of Medicine’s impact on precision and genomic medicine","authors":"Huan Mo, J. Denny","doi":"10.3233/ISU-210144","DOIUrl":"https://doi.org/10.3233/ISU-210144","url":null,"abstract":"Precision medicine offers the potential to improve health through deeper understandings of the lifestyle, biological, and environmental influences on health. Under Dr. Donald A. B. Lindberg’s leadership, the U.S. National Library of Medicine (NLM) has developed the central reference resources for biomedical research and molecular laboratory medicine that enable precision medicine. The hosting and curation of biomedical knowledge repositories and data by NLM enable quality information reachable for providers and researchers throughout the world. NLM has been supporting the innovation of electronic health record systems to implement computability and secondary use for biomedical research, producing the scale of linked health and molecular datasets necessary for precision medicine discovery.","PeriodicalId":39698,"journal":{"name":"Information Services and Use","volume":"30 1","pages":"71 - 80"},"PeriodicalIF":0.0,"publicationDate":"2022-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90361123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
As a young pathologist, Donald A.B. Lindberg, M.D., tirelessly sought scientific solutions to clinical and research problems. Directing several clinical laboratories at the University of Missouri in Columbia, Dr. Lindberg developed the world’s first computerized laboratory information system, speeding analysis and reporting. He directed his team in building computer systems to help clinicians retrieve medical knowledge, enable patients to find information about personal or family health issues, and provide expert automated assistance to physicians in reaching differential diagnoses outside their specialties. Developing superior functionalities with the limited information technologies of the time, Dr. Lindberg’s pioneering work in Columbia foreshadowed his subsequent inspired leadership as Director of the United States National Library of Medicine.
{"title":"A scientific mind embraces medicine: Donald Lindberg’s education and early career","authors":"L. Kingsland, C. Kulikowski","doi":"10.3233/ISU-210140","DOIUrl":"https://doi.org/10.3233/ISU-210140","url":null,"abstract":"As a young pathologist, Donald A.B. Lindberg, M.D., tirelessly sought scientific solutions to clinical and research problems. Directing several clinical laboratories at the University of Missouri in Columbia, Dr. Lindberg developed the world’s first computerized laboratory information system, speeding analysis and reporting. He directed his team in building computer systems to help clinicians retrieve medical knowledge, enable patients to find information about personal or family health issues, and provide expert automated assistance to physicians in reaching differential diagnoses outside their specialties. Developing superior functionalities with the limited information technologies of the time, Dr. Lindberg’s pioneering work in Columbia foreshadowed his subsequent inspired leadership as Director of the United States National Library of Medicine.","PeriodicalId":39698,"journal":{"name":"Information Services and Use","volume":"951 1","pages":"11 - 19"},"PeriodicalIF":0.0,"publicationDate":"2022-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85544401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
When Donald A.B. Lindberg M.D. became Director in 1984, the U.S. National Library of Medicine (NLM) was a leader in the development and use of information standards for published literature but had no involvement with standards for clinical data. When Dr. Lindberg retired in 2015, NLM was the Central Coordinating Body for Clinical Terminology Standards within the U.S. Department of Health and Human Services, a major funder of ongoing maintenance and free dissemination of clinical terminology standards required for use in U.S. electronic health records (EHRs), and the provider of many services and tools to support the use of terminology standards in health care, public health, and research. This chapter describes key factors in the transformation of NLM into a significant player in the establishment of U.S. terminology standards for electronic health records.
{"title":"The U.S. National Library of Medicine and standards for electronic health records: One thing led to another","authors":"C. McDonald, B. Humphreys","doi":"10.3233/ISU-210142","DOIUrl":"https://doi.org/10.3233/ISU-210142","url":null,"abstract":"When Donald A.B. Lindberg M.D. became Director in 1984, the U.S. National Library of Medicine (NLM) was a leader in the development and use of information standards for published literature but had no involvement with standards for clinical data. When Dr. Lindberg retired in 2015, NLM was the Central Coordinating Body for Clinical Terminology Standards within the U.S. Department of Health and Human Services, a major funder of ongoing maintenance and free dissemination of clinical terminology standards required for use in U.S. electronic health records (EHRs), and the provider of many services and tools to support the use of terminology standards in health care, public health, and research. This chapter describes key factors in the transformation of NLM into a significant player in the establishment of U.S. terminology standards for electronic health records.","PeriodicalId":39698,"journal":{"name":"Information Services and Use","volume":"186 1","pages":"81 - 94"},"PeriodicalIF":0.0,"publicationDate":"2022-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78530252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Among the many contributions of Donald A.B. Lindberg was his work on behalf of a variety or professional organizations in the field of biomedical and health informatics. These began during his early days at the University of Missouri and continued throughout his 30 years at the National Library of Medicine. This chapter summarizes that work, which occurred both through his personal efforts and through the impact of the NLM under his leadership. Examples include his role in the development of organizations themselves (e.g., the International Medical Informatics Association, the American College of Medical Informatics, and the American Medical Informatics Association) and also his contributions to the professional scientific meetings that have advanced the field (e.g., the Symposium on Computer Applications in Medical Care, MEDINFO, and the AMIA Annual Symposium).
Donald A.B. Lindberg的众多贡献之一是他代表生物医学和健康信息学领域的各种专业组织所做的工作。这些从他在密苏里大学的早期开始，一直持续到他在国家医学图书馆的30年。本章总结了他的工作，这些工作是通过他个人的努力和在他领导下的民解运动的影响完成的。例如，他在组织本身的发展中所扮演的角色(例如，国际医学信息学协会、美国医学信息学学院和美国医学信息学协会)，以及他对推动该领域发展的专业科学会议的贡献(例如，医疗保健中的计算机应用研讨会、MEDINFO和AMIA年度研讨会)。
{"title":"Donald A.B. Lindberg, pioneer in biomedical and health informatics: His involvement in creating professional organizations","authors":"J. V. Bemmel, M. Ball, E. Shortliffe","doi":"10.3233/isu-210141","DOIUrl":"https://doi.org/10.3233/isu-210141","url":null,"abstract":"Among the many contributions of Donald A.B. Lindberg was his work on behalf of a variety or professional organizations in the field of biomedical and health informatics. These began during his early days at the University of Missouri and continued throughout his 30 years at the National Library of Medicine. This chapter summarizes that work, which occurred both through his personal efforts and through the impact of the NLM under his leadership. Examples include his role in the development of organizations themselves (e.g., the International Medical Informatics Association, the American College of Medical Informatics, and the American Medical Informatics Association) and also his contributions to the professional scientific meetings that have advanced the field (e.g., the Symposium on Computer Applications in Medical Care, MEDINFO, and the AMIA Annual Symposium).","PeriodicalId":39698,"journal":{"name":"Information Services and Use","volume":"12 1","pages":"21 - 27"},"PeriodicalIF":0.0,"publicationDate":"2022-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85504962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Donald A.B. Lindberg M.D. arrived at the U.S. National Library of Medicine in 1984 and quickly launched the Unified Medical Language System (UMLS) research and development project to help computers understand biomedical meaning and to enable retrieval and integration of information from disparate electronic sources, e.g., patient records, biomedical literature, knowledge bases. This chapter focuses on how Lindberg’s thinking, preferred ways of working, and decision-making guided UMLS goals and development and on what made the UMLS markedly “new and different” and ahead of its time.
Donald A.B. Lindberg医学博士于1984年来到美国国家医学图书馆，并迅速启动了统一医学语言系统(UMLS)研究和开发项目，以帮助计算机理解生物医学的含义，并使检索和整合来自不同电子来源的信息成为可能，例如，患者记录，生物医学文献，知识库。本章重点介绍林德伯格的思想、首选的工作方式和决策是如何指导UMLS的目标和发展的，以及是什么使UMLS明显地“新颖而不同”，领先于时代。
{"title":"Something new and different: The Unified Medical Language System","authors":"B. Humphreys, M. Tuttle","doi":"10.3233/ISU-210138","DOIUrl":"https://doi.org/10.3233/ISU-210138","url":null,"abstract":"Donald A.B. Lindberg M.D. arrived at the U.S. National Library of Medicine in 1984 and quickly launched the Unified Medical Language System (UMLS) research and development project to help computers understand biomedical meaning and to enable retrieval and integration of information from disparate electronic sources, e.g., patient records, biomedical literature, knowledge bases. This chapter focuses on how Lindberg’s thinking, preferred ways of working, and decision-making guided UMLS goals and development and on what made the UMLS markedly “new and different” and ahead of its time.","PeriodicalId":39698,"journal":{"name":"Information Services and Use","volume":"18 1","pages":"95 - 106"},"PeriodicalIF":0.0,"publicationDate":"2022-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83199746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The highest priority new initiative resulting from the 1985–86 National Library of Medicine Long Range Planning exercise initiated by NLM Director Dr. Donald A.B. Lindberg was the creation of new information resources and services related to molecular biology and genetics, termed “biotechnology information”. Beginning with existing NLM resources and research projects associated with molecular data, and with Lindberg’s enthusiastic support, the institution launched a Congressionally-mandated Center that has become an essential part of 21st century biomedical science.
{"title":"Don Lindberg and the creation of the National Center for Biotechnology Information","authors":"D. Masys, D. Benson","doi":"10.3233/ISU-210139","DOIUrl":"https://doi.org/10.3233/ISU-210139","url":null,"abstract":"The highest priority new initiative resulting from the 1985–86 National Library of Medicine Long Range Planning exercise initiated by NLM Director Dr. Donald A.B. Lindberg was the creation of new information resources and services related to molecular biology and genetics, termed “biotechnology information”. Beginning with existing NLM resources and research projects associated with molecular data, and with Lindberg’s enthusiastic support, the institution launched a Congressionally-mandated Center that has become an essential part of 21st century biomedical science.","PeriodicalId":39698,"journal":{"name":"Information Services and Use","volume":"116 1","pages":"107 - 115"},"PeriodicalIF":0.0,"publicationDate":"2022-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74612046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Through his visionary leadership as Director of the U.S. National Library of Medicine (NLM), Donald A. B. Lindberg M.D. influenced future generations of informatics professionals and the field of biomedical informatics itself. This chapter describes Dr. Lindberg’s role in sponsoring and shaping the NLM’s Institutional T15 training programs.
作为美国国家医学图书馆(NLM)的主任，Donald A. B. Lindberg博士通过他富有远见的领导，影响了未来几代信息学专业人士和生物医学信息学领域本身。本章描述了Lindberg博士在赞助和塑造NLM机构T15培训计划方面的作用。
{"title":"Don Lindberg’s influence on future generations: The U.S. National Library of Medicine’s biomedical informatics research training programs","authors":"R. Greenes, V. Florance, R. Miller","doi":"10.3233/ISU-210135","DOIUrl":"https://doi.org/10.3233/ISU-210135","url":null,"abstract":"Through his visionary leadership as Director of the U.S. National Library of Medicine (NLM), Donald A. B. Lindberg M.D. influenced future generations of informatics professionals and the field of biomedical informatics itself. This chapter describes Dr. Lindberg’s role in sponsoring and shaping the NLM’s Institutional T15 training programs.","PeriodicalId":39698,"journal":{"name":"Information Services and Use","volume":"1 1","pages":"39 - 45"},"PeriodicalIF":0.0,"publicationDate":"2022-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79820061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This overview summary of the Informatics Section of the book Transforming biomedical informatics and health information access: Don Lindberg and the U.S. National Library of Medicine illustrates how the NLM revolutionized the field of biomedical and health informatics during Lindberg’s term as NLM Director. Authors present a before-and-after perspective of what changed, how it changed, and the impact of those changes.
{"title":"Donald A.B. Lindberg and the U.S. National Library of Medicine transformed biomedical and health informatics","authors":"R. Miller, E. Shortliffe","doi":"10.3233/ISU-210133","DOIUrl":"https://doi.org/10.3233/ISU-210133","url":null,"abstract":"This overview summary of the Informatics Section of the book Transforming biomedical informatics and health information access: Don Lindberg and the U.S. National Library of Medicine illustrates how the NLM revolutionized the field of biomedical and health informatics during Lindberg’s term as NLM Director. Authors present a before-and-after perspective of what changed, how it changed, and the impact of those changes.","PeriodicalId":39698,"journal":{"name":"Information Services and Use","volume":"6 1","pages":"3 - 10"},"PeriodicalIF":0.0,"publicationDate":"2022-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90049150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The US National Library of Medicine’s Biomedical Informatics Short Course ran from 1992 to 2017, most of that time at the Marine Biological Laboratory in Woods Hole, Massachusetts. Its intention was to provide physicians, medical librarians and others engaged in health care with a basic understanding of the major topics in informatics so that they could return to their home institutions as “change agents”. Over the years, the course provided week-long, intense, morning-to-night experiences for some 1,350 students, consisting of lectures and hands-on project development, taught by many luminaries in the field, not the least of which was Donald A.B. Lindberg M.D., who spoke on topics ranging from bioinformatics to national policy.
{"title":"The biomedical informatics short course at Woods Hole/Georgia: Training to support institutional change","authors":"J. Cimino","doi":"10.3233/isu-210136","DOIUrl":"https://doi.org/10.3233/isu-210136","url":null,"abstract":"The US National Library of Medicine’s Biomedical Informatics Short Course ran from 1992 to 2017, most of that time at the Marine Biological Laboratory in Woods Hole, Massachusetts. Its intention was to provide physicians, medical librarians and others engaged in health care with a basic understanding of the major topics in informatics so that they could return to their home institutions as “change agents”. Over the years, the course provided week-long, intense, morning-to-night experiences for some 1,350 students, consisting of lectures and hands-on project development, taught by many luminaries in the field, not the least of which was Donald A.B. Lindberg M.D., who spoke on topics ranging from bioinformatics to national policy.","PeriodicalId":39698,"journal":{"name":"Information Services and Use","volume":"71 1","pages":"47 - 59"},"PeriodicalIF":0.0,"publicationDate":"2022-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80312382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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