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Enhanced Care Units: Guidance on development and implementation within Acute Medicine. 加强护理单位:急性医学发展和实施指南。
Q3 Medicine Pub Date : 2023-01-01 DOI: 10.52964/AMJA.0929
Nicholas Smallwood, Sanjay Krishnamoorthy, Kathleen Bonnici, Tim Wenham, Paul Dean, Sarah Dyson, Hattie Jones, Andrew Walden, Jennie Stephens, Jan Basey, Tash Kelly, Kirsten Evans

The Society for Acute Medicine (SAM) and Intensive Care Society (ICS) have produced joint guidance on the standards of care and infrastructure required to deliver enhanced care within Acute Medicine. The cohort of patients this relates to are in the most part already being looked after on the AMU, but co-location and providing enhanced monitoring and nursing input will ensure safe, high-quality care can be delivered to them. We strongly support the development of enhanced care units, whilst clearly acknowledging that they are not a replacement for critical care where that is indicated. Enhanced care and critical care complement each other and will help foster the close working between the two specialties that modern acute care requires. This guidance draws on expertise and existing relevant guidance from the two societies, alongside that from the Faculty of Intensive Care Medicine (FICM), British Thoracic Society (BTS), National Institute for Health and Care Excellence (NICE) and NHS England / Improvement (NHSE/I). We recognise this is an area with limited evidence and so will aim to review it regularly as the knowledge and experience in this area increases.

急性医学学会(SAM)和重症监护学会(ICS)已经就在急性医学范围内提供加强护理所需的护理标准和基础设施制定了联合指南。与此相关的患者群体大部分已经在AMU得到照顾,但共同安置和提供加强的监测和护理投入将确保向他们提供安全、高质量的护理。我们强烈支持加强护理单位的发展,同时也清楚地认识到,在需要的情况下,它们不能取代重症监护。强化护理和重症护理相辅相成,将有助于促进现代急性护理所需的两个专业之间的密切合作。该指南借鉴了两个学会的专业知识和现有相关指导,以及重症医学系(FICM)、英国胸科学会(BTS)、国家健康与护理卓越研究所(NICE)和英国国民保健服务体系(NHSE/I)的专业知识和相关指导。我们认识到这是一个证据有限的领域,因此随着这一领域知识和经验的增加,我们将定期对其进行审查。
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引用次数: 0
Listeria Meningitis, one of your five a day? A case report of Listeria Monocytogenes Meningitis in a fit and well 62-year-old woman. 李斯特菌脑膜炎,你每天五个人中的一个吗?一例单核细胞增生李斯特菌脑膜炎在一个健康和良好的62岁妇女。
Q3 Medicine Pub Date : 2023-01-01 DOI: 10.52964/AMJA.0942
L Harrington, G Fisk, M Elanchenny, S Shaikh, U Shah

Listeria Monocytogenes is transmitted via ingestion of contaminated food products and can cause invasive disease in susceptible hosts. Risk factors include immunocompromise; pregnancy; being elderly; and new-born. Listeriosis is uncommon but can occur in immunocompetent individuals and has a high mortality rate. We report a case of a 62-year-old female with no obvious risk factors who presented with atypical meningism. The patient was subsequently diagnosed with listeria meningitis and made a good recovery. The patient was a gardener regularly handling soil and ingested vegetables from her allotment patch; this case is reported to highlight less common risk factors and atypical ways in which listeria may present to the acute medical take.

单核细胞增生李斯特菌通过摄入受污染的食品传播,可在易感宿主中引起侵袭性疾病。危险因素包括免疫功能低下;怀孕;老年人;和新生。李斯特菌病不常见,但可发生在免疫能力强的个体,死亡率高。我们报告一例62岁的女性没有明显的危险因素谁提出了不典型脑膜炎。患者随后被诊断为脑膜炎李斯特菌,并恢复良好。患者是一名园丁,经常处理土壤,并从她分配的土地上摄入蔬菜;据报道,该病例突出了不太常见的危险因素和李斯特菌可能出现在急性医疗采取的非典型方式。
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引用次数: 0
Artificial Intelligence: its Future and Impact on Acute Medicine. 人工智能:它的未来及其对急性医学的影响。
Q3 Medicine Pub Date : 2023-01-01
M Schinkel, K Paranjape, S C Bhagirath, Pwb Nanayakkara

This commentary explores the potential impact of artificial intelligence (AI) in acute medicine, considering its possibilities and challenges. With its ability to simulate human intelligence, AI holds the promise for supporting timely decision-making and interventions in acute care. While AI has significantly contributed to improvements in various sectors, its implementation in healthcare remains limited. The development of AI tools tailored to acute medicine can improve clinical decision-making, and AI's role in streamlining administrative tasks, exemplified by ChatGPT, may offer immediate benefits. However, challenges include uniform data collection, privacy, bias, and preserving the doctor-patient relationship. Collaboration among AI researchers, healthcare professionals, and policymakers is crucial to harness the potential of AI in acute medicine and create a future where advanced technologies synergistically enhance human expertise.

这篇评论探讨了人工智能在急性医学中的潜在影响,考虑了它的可能性和挑战。凭借其模拟人类智能的能力,人工智能有望支持急性护理的及时决策和干预。尽管人工智能对各个领域的改善做出了重大贡献,但其在医疗保健领域的实施仍然有限。为急性医学量身定制的人工智能工具的开发可以改善临床决策,而人工智能在简化管理任务方面的作用,例如ChatGPT,可能会带来立竿见影的好处。然而,挑战包括统一的数据收集、隐私、偏见和维护医患关系。人工智能研究人员、医疗保健专业人员和政策制定者之间的合作对于利用人工智能在急性医学中的潜力并创造一个先进技术协同增强人类专业知识的未来至关重要。
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引用次数: 0
Both acuity and long term prognosis are important Emergency Department metrics: comparison of mobility assessment with the Emergency Severity Index. 敏锐度和长期预后都是急诊科的重要指标:行动能力评估与急诊严重程度指数的比较。
Q3 Medicine Pub Date : 2023-01-01
I Arnold, T Kuster, J M Busch, J G Kellett, M Brabrand, R Bingisser, C H Nickel

Objective: To compare the SUHB mobility scale (i.e., stable(S), unstable gait(U), needing help to walk(H), or bedridden(B)) and the Emergency Severity Index (ESI) associations with admission and mortality outcomes.

Design: Post-hoc analysis of a prospective observational study including all consenting presenting to the ED over a period of 3 weeks. Odd ratios and AUCs were calculated to assess predictive performance of SUHB and compared with ESI.

Results: Out of 2422 patients, 65% presented with a stable gait, 45% with an ESI level 3. With increasing mobility impairment on the SUHB scale, the probability for admission and mortality increased. SUHB had a higher AUC than ESI for 1-year mortality.

Conclusion: SUHB was a better predictor than ESI of long-term mortality. The scale, which is rapid, requires little additional training, and no extra costs, could be used as a useful supplement to the triage process.

目的:比较SUHB行动能力量表(即稳定(S)、步态不稳定(U)、需要帮助行走(H)或卧床不起(B))和紧急情况严重程度指数(ESI)与入院和死亡率的关系。设计:前瞻性观察性研究的事后分析,包括在3周内向ED提交的所有同意书。计算比值比和AUC以评估SUHB的预测性能,并与ESI进行比较。结果:在2422名患者中,65%的患者步态稳定,45%的患者ESI水平为3。随着SUHB量表上活动障碍的增加,入院和死亡的概率增加。SUHB的1年死亡率AUC高于ESI。结论:SUHB是一个比ESI更好的预测长期死亡率的指标。这种规模很快,几乎不需要额外的培训,也不需要额外费用,可以作为分诊过程的有用补充。
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引用次数: 0
Antimicrobial neurotoxicity: an under-recognised cause of delirium. 抗菌神经毒性:谵妄的一个未被认识的原因。
Q3 Medicine Pub Date : 2022-04-01 DOI: 10.52964/AMJA.0908
D. Moynan, E. Maqbool, E. de Barra
Antimicrobial associated encephalopathy (AAE) is a well-documented, though under recognised, adverse event associated with antimicrobial use. Clinical manifestations of AAE are varied, ranging from myoclonus and seizure to an encephalopathy with cerebellar signs. The phenotypic presentation of the encephalopathy syndrome is, in general, governed by the antimicrobial in question. Given its apparent rarity in everyday clinical practice, awareness of AAE is crucial for physicians. We describe a reversible encephalopathy characterised by confusion, myoclonus and stupor in a 76 year old gentleman on antimicrobial therapy for a peri-rectal abscess.
抗菌素相关脑病(AAE)是一种有据可查但未得到充分认识的与抗菌素使用相关的不良事件。AAE的临床表现多种多样,从肌阵挛和癫痫发作到伴有小脑体征的脑病。一般来说,脑病综合征的表型表现是由所讨论的抗菌素控制的。鉴于其在日常临床实践中明显罕见,对AAE的认识对医生至关重要。我们描述了一个可逆性脑病的特点是混乱,肌阵挛和麻木在一个76岁的绅士抗菌治疗直肠周围脓肿。
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引用次数: 0
Developing priorities for quality improvement in acute medicine using a modified Delphi method A consensus process hosted by the Society for Acute Medicine Quality Improvement Committee (SAM-QI). 使用改进的德尔菲方法制定急性医学质量改进的优先事项——由急性医学质量改善委员会(SAM-QI)主持的共识过程。
Q3 Medicine Pub Date : 2022-04-01 DOI: 10.52964/AMJA.0901
A. Kennedy, M. Holland, P. Sullivan, A. Gebril, N. Arora, V. Vijayakumar, A. Hoole, C. Nickel, C. Hodcroft, L. Harrington, M. Wheble, J. Soong, N. Scriven, J. Kellett, K. Slinger, V. Price, J. Alsma, S. Astbury, R. Varia, A. Rigby, C. Subbe
INTRODUCTIONThe SAM Quality Improvement Committee (SAM-QI), set up in 2016, has worked over the last year to determine the priority Acute Medicine QI topics. They have also discussed and put forward proposals to improve QI training for Acute Medicine professionals.METHODSA modified Delphi process was completed over four rounds to determine priority QI topics. Online meetings were also used to develop proposals for QI training.RESULTSSame Day Emergency Care (SDEC) was chosen as the priority topic for QI work within Acute Medicine.CONCLUSIONThe SAM-QI group settled on SDEC being the priority topic for Acute Medicine QI development. Throughout the Delphi process SAM-QI has also developed proposals for QI training that will help Acute Medicine professionals deliver coordinated meaningful improvements in care.
简介SAM质量改进委员会(SAM-QI)成立于2016年,在过去一年中一直致力于确定急性医学QI的优先主题。他们还讨论并提出了改进急性医学专业人员QI培训的建议。方法对德尔菲过程进行了四轮改进,以确定优先QI主题。在线会议也被用来制定QI培训的建议。结果选择日间急救(SDEC)作为急性医学QI工作的优先主题。结论SAM-QI小组确定SDEC是急性医学QI发展的优先课题。在整个德尔菲过程中,SAM-QI还制定了QI培训建议,帮助急性医学专业人员在护理方面提供协调一致的有意义的改进。
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引用次数: 0
Isolated paracetamol-induced acute kidney injury: a systematic review. 对乙酰氨基酚引起的急性肾损伤:一项系统综述。
Q3 Medicine Pub Date : 2022-04-01 DOI: 10.52964/AMJA.0904
M. Williams, J. Coulson
AIMWe sought to characterise the syndrome of isolated paracetamol-induced acute kidney injury (AKI), whose incidence and mechanisms are poorly understood.METHODSUsing systematic review methodology, fifty-six papers relating to paracetamol-induced AKI were identified.RESULTS24 cases of isolated paracetamol-induced AKI were identified and compared to 87 identified cases of concurrent renal and hepatic injury. Paracetamol-induced AKI became detectable 3-4 days after exposure; liver injury, where it occurred, preceded AKI detection by 1 day. Risk factors affecting hepatotoxicity risk do not appear to influence isolated AKI, with no clear associated factors except younger age (mean 18.8 versus 33.1 years).CONCLUSIONSIsolated paracetamol-induced AKI appears commoner in younger patients. Paracetamol-induced AKI occurs late and may go undetected by current treatment guidelines.
目的我们试图描述单独的扑热息痛诱导的急性肾损伤(AKI)的综合征,其发病率和机制尚不清楚。方法采用系统综述的方法,对56篇与扑热息痛诱导的AKI相关的论文进行了鉴定。结果24例分离的对乙酰氨基酚诱导的AKI病例被鉴定,并与87例已鉴定的并发肾和肝损伤病例进行了比较。对乙酰氨基酚诱导的AKI在暴露3-4天后可检测到;发生肝损伤的地方,在AKI检测之前1天。影响肝毒性风险的危险因素似乎不会影响孤立的AKI,除了年龄较小(平均18.8岁对33.1岁)外,没有明确的相关因素。结论:孤立的对乙酰氨基酚诱导的AKI在年轻患者中更常见。对乙酰氨基酚诱导的AKI发生较晚,目前的治疗指南可能未发现。
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引用次数: 0
The prediction of early mortality by the ROX index of oxygenation and respiratory rate in diverse Canadian and Ugandan cohorts of unselected patient: a post-hoc retrospective analysis of 80,558 patient observations. 通过氧合和呼吸速率的ROX指数预测加拿大和乌干达不同队列中未选择患者的早期死亡率:对80558名患者观察结果的事后回顾性分析。
Q3 Medicine Pub Date : 2022-04-01 DOI: 10.52964/AMJA.0900
J. Kellett, F. Sikakulya, C. Nickel
AIMTo investigate the association between in-hospital mortality and the ROX index of respiratory rate and oxygenation in diverse cohorts of unselected patient at different prediction windows.METHODSA retrospective post-hoc analysis of data from a major regional referral Canadian hospital and a low-resource hospital in sub-Saharan Africa.RESULTSFour patient cohorts were examined: Canadian medical, surgical and intensive care unit (ICU) patients, and all patients admitted to an African hospital. In all patients in-hospital mortality rose as ROX declined. Apart from ICU patients, ROX had a high discrimination for death within 72 hours. For non-ICU patients the negative predictive value of death within 72 hours for a ROX value <22 ranged from 0.994 to 1.000 Conclusion: In diverse cohorts of unselected patients, the ROX index has a high discrimination for death within 72 hours. However, the index has little or no prognostic value for patient admitted to ICU.
目的探讨不同预测窗期未入选患者不同队列的住院死亡率与呼吸频率和氧合ROX指数的相关性。方法回顾性分析来自加拿大一家主要区域转诊医院和撒哈拉以南非洲一家资源匮乏医院的数据。结果对四组患者进行了检查:加拿大内科、外科和重症监护病房(ICU)患者,以及非洲一家医院的所有患者。在所有患者中,住院死亡率随着ROX的下降而上升。除ICU患者外,ROX对72小时内死亡的歧视程度较高。对于非icu患者,ROX值<22对72小时内死亡的阴性预测值在0.994 ~ 1.000之间。结论:在不同的非入选患者队列中,ROX指数对72小时内死亡具有较高的判别性。然而,该指数对ICU住院患者的预后价值很小或没有价值。
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引用次数: 2
Shock first, ask questions later…. 先震惊,后提问…。
Q3 Medicine Pub Date : 2022-04-01 DOI: 10.52964/AMJA.0905
B. Brown, M. Jackson
A 39-year-old man presented to the Emergency Department following a sudden onset of palpitations an hour earlier. He was clammy and felt generally unwell. He was normally fit and active with no history of cardiac symptoms including palpitations - he mentioned as a teenager he was told that he had an 'extra bit of wiring in his heart' but nothing further was done. His only regular medication was Sertraline. He drank alcohol to excess. On examination, he was hypotensive but pain free. Bloods including potassium and magnesium were within normal limits - venous lactate was mildly elevated at 2.8.
一名39岁的男子在一小时前突然出现心悸后来到急诊科。他浑身湿漉漉的,全身不舒服。他身体健康,身体活跃,没有心悸等心脏症状。他说,十几岁的时候,他被告知“心脏里有一段额外的线路”,但没有做任何进一步的检查。他唯一的常规药物是舍曲林。他酗酒过度。经检查,他有低血压,但无疼痛。血液包括钾和镁在正常范围内-静脉乳酸轻度升高至2.8。
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引用次数: 0
Improving care for patients in the outlying wards: Lessons from patients' care experience. 改善边远病区患者护理:来自患者护理经验的教训。
Q3 Medicine Pub Date : 2022-04-01 DOI: 10.52964/AMJA.0902
V. Sobolewska, H. Duff, F. Craighead, I. Macpherson, A. Veiraiah, S. Dummer, K. Lockman
IMPORTANCEOvercrowding in hospitals and lack of capacity in general medical wards can result in a medical patient being transferred to other specialty wards often referred as 'outlying' or 'boarding' wards.OBJECTIVESWe explored the experiences of our outlying patients to identify local factors that affect their care experience and inform interventions that could improve their care deliveries and outcomes.DESIGN, SETTING, AND PARTICIPANTSQualitative interviews using semi-structured questions were conducted in 21 medical patients from a mixture of specialty wards in a large tertiary NHS hospital.MAIN OUTCOMES AND MEASURESPerceptions of the factors contributing to the experience of being a patient on a boarding ward, and potential solutions.RESULTSAlmost all participants reported experiences of good care in an outlying ward. Positive comments highlighted good nursing care, restful environment and a strong focus on patient-centred care. However, none of the participants could identify the team or consultant responsible for their care and this was linked to multiple doctors being involved in the patient's care. Participants also perceived that the frequency of review was reduced and occurred much later in the day than that experienced in the medical ward. Most felt indifferent about the care ownership, timing and frequency of review but in some cases, this led to confusion and the perception of poor progress. Further, participants felt that they had to actively seek information relating to clinical progress. Negative experience of discharge planning was also reported. The associated themes included conflicting information and delays in social care provision. This led to anxiety, frustration and the perception of being a barrier to patient flow.CONCLUSIONS AND RELEVANCEPatient experience of the outlying ward is positive, and this can provide a foundation for improvement. Our findings suggest that better care processes and improved communication are needed to promote equity and quality of care. However, this should be complemented with efforts to overcome wider challenges that affect the entire continuum of flow within the healthcare system.
重要性医院过度拥挤和普通病房容量不足可能导致病人被转移到其他专科病房,通常被称为“边远”或“寄宿”病房。目的:我们探讨边远地区患者的经历,以确定影响其护理体验的当地因素,并告知可以改善其护理交付和结果的干预措施。设计、环境和参与者采用半结构化问题对来自一家大型三级NHS医院混合专科病房的21名患者进行了定性访谈。主要结果和测量对住院病人体验的影响因素的看法,以及可能的解决方案。结果几乎所有的参与者都报告了在偏远病房的良好护理经历。积极的评价强调了良好的护理、宁静的环境和以病人为中心的护理。然而,没有一个参与者能够确定负责他们护理的团队或顾问,这与参与患者护理的多名医生有关。参与者还认为,审查的频率减少了,而且比在医疗病房中经历的要晚得多。大多数人对护理所有权、时间和审查频率感到漠不关心,但在某些情况下,这导致了混乱和进展不佳的感觉。此外,参与者认为他们必须积极寻求与临床进展有关的信息。也报告了出院计划方面的消极经验。相关主题包括相互矛盾的信息和社会保健服务的延误。这导致了焦虑、沮丧和患者流动障碍的感觉。结论及相关结论:边远病区的患者体验是积极的,可为今后的改进提供基础。我们的研究结果表明,需要更好的护理流程和改善沟通,以促进公平和护理质量。然而,这应该与努力克服影响医疗保健系统内整个连续流动的更广泛挑战相辅相成。
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引用次数: 0
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Acute Medicine
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