- Chronic liver disorders are the major causes of illness and mortality worldwide. Patients with chronic liver diseases have a greater chance of developing cirrhosis, hepatocellular carcinoma, progressive liver fibrosis, and subsequently liver failure. Currently there are no effective treatments available for patients with the various kinds of liver diseases. The use of nanotechnology is considered a rapidly growing field of interest for the safe and targeted delivery of insufficiently water-insoluble hepatoprotective drugs. Therefore, the nanoparticle combination improves bioavailability and plasma stability of drugs with poor aqueous solubility. Thus, this study aims at developing chemically and physically stable Fenretinide loaded solid lipid nanoparticles (FEN-SLNs) for successful delivery to the liver. The nanoencapsulation of FEN in Gelucire-based, surfactant-free SLNs was developed. SLNs were characterized in terms of physicochemical properties, surface morphology, drug loading, release behavior as well as in vivo biodistribution study. The results showed that adopting hot homogenization method for preparation of FEN loaded solid lipid nanoparticles using Gelucire 50/13 and Precirol provided chemically and physically stable FEN-SLNs. Further, the optimized FEN-SLNs has particle size 298.3 ± 2.54 and PDI 0.3 with negative zeta potential -15.2 ± 3.61 mV, and Entrapment efficiency exceeding 92%. Furthermore, in vitro release experiment ensured sustained release of FEN over > 24 h with no signs of degradation. In addition, TEM photomicrographs showed spherical particles. Noteworthy, the in vivo biodistribution results showed that fluorescently labeled SLNs retained in the liver for 8h with diminished migration to the other organs unlike the free dye. In conclusion the study highlights the effective encapsulation of FEN and effective delivery to the liver.
{"title":"Formulation, Optimization, and Invitro Characterization of Lipid-Based Nanoparticles for Effective Delivery to The Liver","authors":"Dina M. Gaber, Nabila Borae, M. Gayed","doi":"10.11159/icnfa23.107","DOIUrl":"https://doi.org/10.11159/icnfa23.107","url":null,"abstract":"- Chronic liver disorders are the major causes of illness and mortality worldwide. Patients with chronic liver diseases have a greater chance of developing cirrhosis, hepatocellular carcinoma, progressive liver fibrosis, and subsequently liver failure. Currently there are no effective treatments available for patients with the various kinds of liver diseases. The use of nanotechnology is considered a rapidly growing field of interest for the safe and targeted delivery of insufficiently water-insoluble hepatoprotective drugs. Therefore, the nanoparticle combination improves bioavailability and plasma stability of drugs with poor aqueous solubility. Thus, this study aims at developing chemically and physically stable Fenretinide loaded solid lipid nanoparticles (FEN-SLNs) for successful delivery to the liver. The nanoencapsulation of FEN in Gelucire-based, surfactant-free SLNs was developed. SLNs were characterized in terms of physicochemical properties, surface morphology, drug loading, release behavior as well as in vivo biodistribution study. The results showed that adopting hot homogenization method for preparation of FEN loaded solid lipid nanoparticles using Gelucire 50/13 and Precirol provided chemically and physically stable FEN-SLNs. Further, the optimized FEN-SLNs has particle size 298.3 ± 2.54 and PDI 0.3 with negative zeta potential -15.2 ± 3.61 mV, and Entrapment efficiency exceeding 92%. Furthermore, in vitro release experiment ensured sustained release of FEN over > 24 h with no signs of degradation. In addition, TEM photomicrographs showed spherical particles. Noteworthy, the in vivo biodistribution results showed that fluorescently labeled SLNs retained in the liver for 8h with diminished migration to the other organs unlike the free dye. In conclusion the study highlights the effective encapsulation of FEN and effective delivery to the liver.","PeriodicalId":398088,"journal":{"name":"Proceedings of the 9th World Congress on New Technologies","volume":"172 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131109968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sai Krishna Duddupudi, Sreekar Varma Penmetsa, Madhu Kumar Kumara, Nikhil Sai Raghav Vasili, D. Bhattacharyya, Keerthi Katam
– The main objective of this study is to evaluate the water quality of Durgam Cheruvu Lake, Hyderabad, India by comprehensively analysing organic micropollutants. Samples were collected from three different sites in the lake and nontargeted screening was performed using liquid chromatography-quadrupole time-of-flight (LC-QTOF). A total of 183 compounds were detected in all samples. This includes pharmaceuticals, herbicides, fungicides, pesticides, hormones, steroids, UV filters, plasticizers, cyanotoxins, and metabolites. In all samples, pharmaceuticals accounted for approximately 50%, herbicides 8%, and metabolites 9%. The high abundance va lues were observed for 17 α β – Dihydroequilin, Avobenzone, Sibutramine, Butachlor, Napropamide, and Estriol at all the sampling locations. Estriol and 17αβ – Dihydroequilin are classified as the largest endocrine disruptors among many micropollutants. Eutrophication-related cyanotoxins including Microcystin-LR and Anatoxin-A have been identified in the lake. Additionally, the urine metabolites of Clarithromycin, Flunitrazepam, and other transformed metabolites of cocaine-d3 and Amitriptyline were discovered. Overall, veterinary medications, narcotic pharmaceuticals, pain killers, anti-psychotic, anti-depressant, and anti-obesity drugs were found to be the most prevalent components in the lake samples, indicating the discharge of domestic and industrial wastewater into the lake.
{"title":"Non-Target Screening Of Organic Micropollutants In Durgam Cheruvu Lake, India","authors":"Sai Krishna Duddupudi, Sreekar Varma Penmetsa, Madhu Kumar Kumara, Nikhil Sai Raghav Vasili, D. Bhattacharyya, Keerthi Katam","doi":"10.11159/icepr23.147","DOIUrl":"https://doi.org/10.11159/icepr23.147","url":null,"abstract":"– The main objective of this study is to evaluate the water quality of Durgam Cheruvu Lake, Hyderabad, India by comprehensively analysing organic micropollutants. Samples were collected from three different sites in the lake and nontargeted screening was performed using liquid chromatography-quadrupole time-of-flight (LC-QTOF). A total of 183 compounds were detected in all samples. This includes pharmaceuticals, herbicides, fungicides, pesticides, hormones, steroids, UV filters, plasticizers, cyanotoxins, and metabolites. In all samples, pharmaceuticals accounted for approximately 50%, herbicides 8%, and metabolites 9%. The high abundance va lues were observed for 17 α β – Dihydroequilin, Avobenzone, Sibutramine, Butachlor, Napropamide, and Estriol at all the sampling locations. Estriol and 17αβ – Dihydroequilin are classified as the largest endocrine disruptors among many micropollutants. Eutrophication-related cyanotoxins including Microcystin-LR and Anatoxin-A have been identified in the lake. Additionally, the urine metabolites of Clarithromycin, Flunitrazepam, and other transformed metabolites of cocaine-d3 and Amitriptyline were discovered. Overall, veterinary medications, narcotic pharmaceuticals, pain killers, anti-psychotic, anti-depressant, and anti-obesity drugs were found to be the most prevalent components in the lake samples, indicating the discharge of domestic and industrial wastewater into the lake.","PeriodicalId":398088,"journal":{"name":"Proceedings of the 9th World Congress on New Technologies","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124200555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Qin, Fanbin Meng, Liming Ren, Jianlin Jiang, H. Gong
- Petroleum-contaminated soils are difficult to remediate due to a wide range of point/nonpoint sources of pollution and complex components. Here, the optimizations of the leaching process and process parameters were carried out based on the selection of conventional eluting agents and the development of oligomers, modified bio-based surfactants and synergists. Furthermore, a new and efficient leaching system was constructed. Moreover, based on the characteristics of the soil after leaching and its flora structure, the best degradation flora was selected and optimized. The proposed leaching-bioremediation coupling treatment process could make the petroleum hydrocarbon content of the contaminated soil less than 0.45%. The field validation was also conducted for petroleum hydrocarbon-contaminated soil with a mass of 12 000 t. Finally, the economic and environmentally friendly remediation technology and process for oil-contaminated soil are established. This approach can provide technical support for the environmental protection of sudden oil pollution and other historical problems in oil areas.
{"title":"Coupling Leaching-Bioremediation for Petroleum-Contaminated Soil","authors":"B. Qin, Fanbin Meng, Liming Ren, Jianlin Jiang, H. Gong","doi":"10.11159/icepr23.114","DOIUrl":"https://doi.org/10.11159/icepr23.114","url":null,"abstract":"- Petroleum-contaminated soils are difficult to remediate due to a wide range of point/nonpoint sources of pollution and complex components. Here, the optimizations of the leaching process and process parameters were carried out based on the selection of conventional eluting agents and the development of oligomers, modified bio-based surfactants and synergists. Furthermore, a new and efficient leaching system was constructed. Moreover, based on the characteristics of the soil after leaching and its flora structure, the best degradation flora was selected and optimized. The proposed leaching-bioremediation coupling treatment process could make the petroleum hydrocarbon content of the contaminated soil less than 0.45%. The field validation was also conducted for petroleum hydrocarbon-contaminated soil with a mass of 12 000 t. Finally, the economic and environmentally friendly remediation technology and process for oil-contaminated soil are established. This approach can provide technical support for the environmental protection of sudden oil pollution and other historical problems in oil areas.","PeriodicalId":398088,"journal":{"name":"Proceedings of the 9th World Congress on New Technologies","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132227001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Bermeo-Campos, F. Salazar, A. Trejo, Á. Miranda, M. Cruz‐Irisson
Extended Abstract Since the discovery of photoluminescence in nanoporous silicon in 1990, nanoporous semiconductors have attracted much attention due to their different properties and potential applications. Compared to porous silicon, nanoporous Germanium (pGe) has been less studied, due to its difficult synthesis that involves a bipolar electrochemical etching in hydrochloric acid, compared to the rather simple synthesis of porous Silico. However, pGe has been used in optoelectronics as photodetector, battery electrode for energy storage and backside reflector for photovoltaics. However, the theoretical characterization of this material is still scarce, this kind of investigation could be of the outmost importance in order to accelerate the development of applications using this nanostructured material, especially the determination of their vibrational properties which could indicate the stability of this material and its thermodynamic properties which are crucial for electronic and thermoelectric applications, also vibrational spectroscopies such as Raman and Infrared are intrinsically linked to the vibrational properties, by modelling these spectrums experimental investigations have a valuable resource for comparison since these are two of the most used non-destructive characterization techniques. In this work we study the vibrational properties of pGe using the first principles density functional perturbation theory and the supercell scheme [1,2 ]. The nanoporous structures are modelled by removing
{"title":"Effects Of Chlorine And Fluorine On The Vibrational Properties Of Nanoporous Germanium: A Theoretical Approach","authors":"R. Bermeo-Campos, F. Salazar, A. Trejo, Á. Miranda, M. Cruz‐Irisson","doi":"10.11159/icnfa23.124","DOIUrl":"https://doi.org/10.11159/icnfa23.124","url":null,"abstract":"Extended Abstract Since the discovery of photoluminescence in nanoporous silicon in 1990, nanoporous semiconductors have attracted much attention due to their different properties and potential applications. Compared to porous silicon, nanoporous Germanium (pGe) has been less studied, due to its difficult synthesis that involves a bipolar electrochemical etching in hydrochloric acid, compared to the rather simple synthesis of porous Silico. However, pGe has been used in optoelectronics as photodetector, battery electrode for energy storage and backside reflector for photovoltaics. However, the theoretical characterization of this material is still scarce, this kind of investigation could be of the outmost importance in order to accelerate the development of applications using this nanostructured material, especially the determination of their vibrational properties which could indicate the stability of this material and its thermodynamic properties which are crucial for electronic and thermoelectric applications, also vibrational spectroscopies such as Raman and Infrared are intrinsically linked to the vibrational properties, by modelling these spectrums experimental investigations have a valuable resource for comparison since these are two of the most used non-destructive characterization techniques. In this work we study the vibrational properties of pGe using the first principles density functional perturbation theory and the supercell scheme [1,2 ]. The nanoporous structures are modelled by removing","PeriodicalId":398088,"journal":{"name":"Proceedings of the 9th World Congress on New Technologies","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133227375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
By 2040, the number of new cancer cases per year is expected to rise to 29.5 million and the number of cancer-related deaths to 16.4 million. Approximately 50 percent of all cancer patients can benefit from radiotherapy (RT). Although an increasing number of patients survive at least five years past their cancer diagnosis, cancer continues to be the leading cause of death worldwide. RT is an essential element of curative treatment of many cancers including breast, prostate, cervix, head and neck, lung, and brain. For prostate cancer, radiotherapy dose-escalation is known to improve disease control, but can also increase late normal tissue toxicity. Despite advancements in treatment planning & delivery we are now approaching the limit of RT dose that can be safely delivered to patients, creating a clear need for novel methods to enhance radiotherapy effects to further improve the survival, while reducing side effects. Enhancing targeted delivery of radiotherapy (RT) has tremendous potential to maximize the effect of dose given to the tumor and reduce the dose given to normal tissue. One of the current strategies to preferentially increase tumor radiation dose effect is to add a radiosensitizer to RT, which has improved survival for those with cancers. Dr. Chithrani uses gold nanoparticles in combination with other radiation sensitizing agents to optimize current radiotherapy. In this talk, she will discuss the promising outcomes of such novel strategies to overcome current challenges imposed by the tumour and its microenvironment.
{"title":"Nanomedicine as a Promising Approach to Overcome Current Challenges in Cancer Radiotherapy","authors":"D. Chithrani","doi":"10.11159/icnfa23.002","DOIUrl":"https://doi.org/10.11159/icnfa23.002","url":null,"abstract":"By 2040, the number of new cancer cases per year is expected to rise to 29.5 million and the number of cancer-related deaths to 16.4 million. Approximately 50 percent of all cancer patients can benefit from radiotherapy (RT). Although an increasing number of patients survive at least five years past their cancer diagnosis, cancer continues to be the leading cause of death worldwide. RT is an essential element of curative treatment of many cancers including breast, prostate, cervix, head and neck, lung, and brain. For prostate cancer, radiotherapy dose-escalation is known to improve disease control, but can also increase late normal tissue toxicity. Despite advancements in treatment planning & delivery we are now approaching the limit of RT dose that can be safely delivered to patients, creating a clear need for novel methods to enhance radiotherapy effects to further improve the survival, while reducing side effects. Enhancing targeted delivery of radiotherapy (RT) has tremendous potential to maximize the effect of dose given to the tumor and reduce the dose given to normal tissue. One of the current strategies to preferentially increase tumor radiation dose effect is to add a radiosensitizer to RT, which has improved survival for those with cancers. Dr. Chithrani uses gold nanoparticles in combination with other radiation sensitizing agents to optimize current radiotherapy. In this talk, she will discuss the promising outcomes of such novel strategies to overcome current challenges imposed by the tumour and its microenvironment.","PeriodicalId":398088,"journal":{"name":"Proceedings of the 9th World Congress on New Technologies","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133232873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Extended Abstract As global warming becomes serious with the increase of greenhouse gases, interest in the impact of climate change on the global environment and human life is increasing. In addition, local abnormal climate phenomena frequently appear according to climate change, and changes in the ecosystem are starting to be detected. Indicators that reflect climate change are diverse, such as agriculture, plant and animal distribution, biological seasons and ecology, and health. Here, the impact on agricultural production in particular seems to be very important [1]. Satellite products such as NDVI (Normalized Difference Vegetation Index), LAI (Leaf Area Index), FPAR (Fraction of Photosynthetically Active Radiation), and PET (Potential EvapoTranspiration) that reflect the growth and vitality of vegetation exist. Through this, changes in agricultural land or forests can be identified. At this time, strict atmospheric correction for high-resolution satellite data is essential in order to use accurate product. The radiation measured at a satellite sensor can have errors due to atmospheric effects such as scattering and absorption while transmitting from the land surface to the sensor. Absorption of sunlight by the atmosphere attenuates the radiation measured using the sensor. Since atmospheric effects in remote sensing cause uncertainty in surface observation, accurate atmospheric correction is an essential preprocessing step for the analysis of surface characterization and environmental monitoring [2]. Among atmospheric correction methods, the physical model-based method has the advantage of calculating the atmospheric contribution numerically using the precise Radiative Transfer Model (RTM) and using it for atmospheric
{"title":"Atmospheric correction of Sentinel-2 images for accurate identification of vegetation distribution","authors":"Seoyeon Kim, Y. Lee","doi":"10.11159/icepr23.116","DOIUrl":"https://doi.org/10.11159/icepr23.116","url":null,"abstract":"Extended Abstract As global warming becomes serious with the increase of greenhouse gases, interest in the impact of climate change on the global environment and human life is increasing. In addition, local abnormal climate phenomena frequently appear according to climate change, and changes in the ecosystem are starting to be detected. Indicators that reflect climate change are diverse, such as agriculture, plant and animal distribution, biological seasons and ecology, and health. Here, the impact on agricultural production in particular seems to be very important [1]. Satellite products such as NDVI (Normalized Difference Vegetation Index), LAI (Leaf Area Index), FPAR (Fraction of Photosynthetically Active Radiation), and PET (Potential EvapoTranspiration) that reflect the growth and vitality of vegetation exist. Through this, changes in agricultural land or forests can be identified. At this time, strict atmospheric correction for high-resolution satellite data is essential in order to use accurate product. The radiation measured at a satellite sensor can have errors due to atmospheric effects such as scattering and absorption while transmitting from the land surface to the sensor. Absorption of sunlight by the atmosphere attenuates the radiation measured using the sensor. Since atmospheric effects in remote sensing cause uncertainty in surface observation, accurate atmospheric correction is an essential preprocessing step for the analysis of surface characterization and environmental monitoring [2]. Among atmospheric correction methods, the physical model-based method has the advantage of calculating the atmospheric contribution numerically using the precise Radiative Transfer Model (RTM) and using it for atmospheric","PeriodicalId":398088,"journal":{"name":"Proceedings of the 9th World Congress on New Technologies","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123794107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Vargas, Carlos Gordillo-Andia,, Danny Tupayachy-Quispe, Jonathan Almirón, F. Roudet
. Lactic acid has several applications in the pharmaceutical, food, cosmetic and chemical industries
． 乳酸在制药、食品、化妆品和化学工业中有多种应用
{"title":"Influence Of Kluyveromyces Lactis Arranged In Suspension And Immobilized On Obtaining Lactic Acid By Cheese Whey Fermentation","authors":"María Vargas, Carlos Gordillo-Andia,, Danny Tupayachy-Quispe, Jonathan Almirón, F. Roudet","doi":"10.11159/icbb23.108","DOIUrl":"https://doi.org/10.11159/icbb23.108","url":null,"abstract":". Lactic acid has several applications in the pharmaceutical, food, cosmetic and chemical industries","PeriodicalId":398088,"journal":{"name":"Proceedings of the 9th World Congress on New Technologies","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126143501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Extended Abstract In this study, a planar UV reactor with distinct UV-C LED arrangements was proposed to treat potable water. The particle tracing method combined with computational fluid dynamics were used to simulate water velocity field, microbial trajectory and exposure time. The ray tracing method was used to determine the irradiance distribution in water. The simulated variables were integrated to determine the distribution of fluence in water. UV light has been widely used in water sterilization processes because it is safe and simple and does not produce any unwanted by-products [1]. UV-C LEDs have been used instead of mercury lamps in water disinfection processes because of their numerous advantages, such as their long lifespan, mercury-free design, tunable wavelength, and high design flexibility [2,3]. The arrangement of UV-C LEDs substantially affects the light distribution and UV fluence to which microbes are subjected. However, if the distribution of light is not optimized, the performance of reactors employing UV LEDs may be lower than that of reactors employing traditional mercury lamps [4] . According to studies on the application of UV-C LEDs in water disinfection in flow reactors, positively correlating the flow field with the irradiation distribution can aid in the design of highly efficient UV reactors. In this study, the effects of LED arrangement on the efficacy of a planar UV LED reactor for E. coli disinfection under various flow rates were investigated. In this experiment, E. coli IFO 3301 was used to validate the water disinfection performance of the reactor. The bacteria were cultured on NZCYM broth supplemented with deionized water and grown in an incubator. To determine the reactor’s sterilization performance, plate counting was
在这项研究中，提出了一个具有不同UV- c LED排列的平面UV反应器来处理饮用水。采用粒子示踪法结合计算流体力学模拟了水流速度场、微生物运动轨迹和暴露时间。采用射线追踪法测定了水中的辐照度分布。对模拟变量进行综合，以确定水中的通量分布。由于紫外线安全、简单，不会产生任何有害的副产物[1]，因此在水杀菌过程中得到了广泛的应用。UV-C led因其寿命长、无汞设计、波长可调、设计灵活性高等诸多优点，已被用于水消毒过程中取代汞灯[2,3]。UV- c led的排列实质上影响了微生物所受的光分布和UV通量。然而，如果不优化光的分布，使用UV led的反应器的性能可能低于使用传统汞灯[4]的反应器。通过UV- c led在流动反应器水消毒中的应用研究，将流场与辐照分布正相关，有助于高效UV反应器的设计。本研究考察了LED排列方式对平面UV LED反应器在不同流速下对大肠杆菌消毒效果的影响。本实验采用大肠杆菌IFO 3301对反应器的水消毒性能进行验证。细菌在加去离子水的NZCYM肉汤中培养，并在培养箱中生长。为了确定反应器的灭菌性能，进行了平板计数
{"title":"The investigation of UV-C LED arrangement on the sterilization of Escherichia coli in flow reactors","authors":"Chien-Ping Wang, Jun Liao","doi":"10.11159/icepr23.121","DOIUrl":"https://doi.org/10.11159/icepr23.121","url":null,"abstract":"Extended Abstract In this study, a planar UV reactor with distinct UV-C LED arrangements was proposed to treat potable water. The particle tracing method combined with computational fluid dynamics were used to simulate water velocity field, microbial trajectory and exposure time. The ray tracing method was used to determine the irradiance distribution in water. The simulated variables were integrated to determine the distribution of fluence in water. UV light has been widely used in water sterilization processes because it is safe and simple and does not produce any unwanted by-products [1]. UV-C LEDs have been used instead of mercury lamps in water disinfection processes because of their numerous advantages, such as their long lifespan, mercury-free design, tunable wavelength, and high design flexibility [2,3]. The arrangement of UV-C LEDs substantially affects the light distribution and UV fluence to which microbes are subjected. However, if the distribution of light is not optimized, the performance of reactors employing UV LEDs may be lower than that of reactors employing traditional mercury lamps [4] . According to studies on the application of UV-C LEDs in water disinfection in flow reactors, positively correlating the flow field with the irradiation distribution can aid in the design of highly efficient UV reactors. In this study, the effects of LED arrangement on the efficacy of a planar UV LED reactor for E. coli disinfection under various flow rates were investigated. In this experiment, E. coli IFO 3301 was used to validate the water disinfection performance of the reactor. The bacteria were cultured on NZCYM broth supplemented with deionized water and grown in an incubator. To determine the reactor’s sterilization performance, plate counting was","PeriodicalId":398088,"journal":{"name":"Proceedings of the 9th World Congress on New Technologies","volume":"325 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133954099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Accelerating Renewable Energy by Artificial Intelligence","authors":"F. Márquez","doi":"10.11159/icert23.001","DOIUrl":"https://doi.org/10.11159/icert23.001","url":null,"abstract":"","PeriodicalId":398088,"journal":{"name":"Proceedings of the 9th World Congress on New Technologies","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134381974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Encapsulation of Sertraline in Biodegradable Polymeric Nanoparticles","authors":"Bushra Alquadeib","doi":"10.11159/icepr23.132","DOIUrl":"https://doi.org/10.11159/icepr23.132","url":null,"abstract":"","PeriodicalId":398088,"journal":{"name":"Proceedings of the 9th World Congress on New Technologies","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116938197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：