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Persons and their affective experiences. Comment on “The affective grounds of the mind. The affective pertinentization (APER) model” by salvatore et al. 人及其情感体验。评论 "心灵的情感基础。情感相关化（APER）模型 "的评论。
IF 13.7 1区 生物学 Q1 BIOLOGY
Physics of Life Reviews
Pub Date : 2024-11-09 DOI: 10.1016/j.plrev.2024.11.005
Tania Zittoun
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引用次数: 0
Affect and human functioning: Comment on the affective grounds of the mind: The Affective Pertinientization (APER) model by S. Salvatore, A. Palmieri, R. De Luca Picione, V. Bochnicchio, M. Reho, M. Rita Serio, G. Salvatore 情感与人类功能：评论心灵的情感基础：S. Salvatore、A. Palmieri、R. De Luca Picione、V. Bochnicchio、M. Reho、M. Rita Serio、G. Salvatore 所著的《情感警觉化（APER）模型》。
IF 13.7 1区 生物学 Q1 BIOLOGY
Physics of Life Reviews
Pub Date : 2024-11-09 DOI: 10.1016/j.plrev.2024.11.006
Stephen Soldz
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引用次数: 0
The circuit of cognition: Operational closure and the interpenetration of views. Comment on “The affective grounds of the mind. The affective pertinentization (APER) model” by Salvatore et al. 认知回路：操作封闭与观点的相互渗透。评论 "心灵的情感基础。情感相关化（APER）模型 "的评论。
IF 13.7 1区 生物学 Q1 BIOLOGY
Physics of Life Reviews
Pub Date : 2024-11-08 DOI: 10.1016/j.plrev.2024.11.003
Gordon Sammut, Rebekah Mifsud, Noellie Brockdorff
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引用次数: 0
What are the psychic forces present within a psychopathological state? Comment on “Nature heals: An informational entropy account of self-organization and change in field psychotherapy” by Pietro Sarasso, Wolfgang Tschacher, Felix Schoeller, Gianni Francesetti, Jan Roubal, Michela Gecele, Katiuscia Sacco, Irene Ronga 精神病理状态中存在哪些精神力量？评论 "自然治愈：Pietro Sarasso、Wolfgang Tschacher、Felix Schoeller、Gianni Francesetti、Jan Roubal、Michela Gecele、Katiuscia Sacco、Irene Ronga 对 "自然治愈：场心理疗法中自我组织和变化的信息熵解释 "的评论。
IF 13.7 1区 生物学 Q1 BIOLOGY
Physics of Life Reviews
Pub Date : 2024-11-08 DOI: 10.1016/j.plrev.2024.11.001
G. de Felice
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引用次数: 0
Affective dynamics in unionization and solidarity: Comment on “The affective grounds of the mind. The Affective Pertinentization (APER) model” by Salvatore et al. 工会和团结中的情感动力：对 Salvatore 等人所著 "心灵的情感基础。Salvatore 等人的 "情感化模式（APER）"一文的评论。
IF 13.7 1区 生物学 Q1 BIOLOGY
Physics of Life Reviews
Pub Date : 2024-11-07 DOI: 10.1016/j.plrev.2024.11.002
Kevin R. Carriere , Michael Richardson
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引用次数: 0
Invited Review for 20th Anniversary Special Issue of PLRev “AI for Mechanomedicine” PLRev 20 周年特刊 "AI for Mechanomedicine "特邀评论。
IF 13.7 1区 生物学 Q1 BIOLOGY
Physics of Life Reviews
Pub Date : 2024-10-24 DOI: 10.1016/j.plrev.2024.10.010
Ning Xie , Jin Tian , Zedong Li , Nianyuan Shi , Bin Li , Bo Cheng , Ye Li , Moxiao Li , Feng Xu
Mechanomedicine is an interdisciplinary field that combines different areas including biomechanics, mechanobiology, and clinical applications like mechanodiagnosis and mechanotherapy. The emergence of artificial intelligence (AI) has revolutionized mechanomedicine, providing advanced tools to analyze the complex interactions between mechanics and biology. This review explores how AI impacts mechanomedicine across four key aspects, i.e., biomechanics, mechanobiology, mechanodiagnosis, and mechanotherapy. AI improves the accuracy of biomechanical characterizations and models, deepens the understanding of cellular mechanotransduction pathways, and enables early disease detection through mechanodiagnosis. In addition, AI optimizes mechanotherapy that targets biomechanical features and mechanobiological markers by personalizing treatment strategies based on real-time patient data. Even with these advancements, challenges still exist, particularly in data quality and the ethical integration into AI in clinical practice. The integration of AI with mechanomedicine offers transformative potential, enabling more accurate diagnostics and personalized treatments, and discovering novel mechanobiological pathways.
机械医学是一个跨学科领域，它结合了生物力学、机械生物学以及机械诊断和机械治疗等临床应用等不同领域。人工智能（AI）的出现彻底改变了机械医学，为分析机械与生物之间复杂的相互作用提供了先进的工具。本综述将探讨人工智能如何在四个关键方面影响机械医学，即生物力学、机械生物学、机械诊断和机械疗法。人工智能提高了生物力学表征和模型的准确性，加深了对细胞机械传导途径的理解，并通过机械诊断实现了早期疾病检测。此外，人工智能还能优化机械疗法，根据患者的实时数据制定个性化治疗策略，以生物力学特征和机械生物学标志物为目标。即使取得了这些进步，挑战依然存在，特别是在数据质量和将人工智能融入临床实践的伦理方面。人工智能与机械医学的结合具有变革潜力，可实现更准确的诊断和个性化治疗，并发现新的机械生物学途径。
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引用次数: 0
More than one effect in every affect 每种影响都有一种以上的效果
IF 13.7 1区 生物学 Q1 BIOLOGY
Physics of Life Reviews
Pub Date : 2024-10-18 DOI: 10.1016/j.plrev.2024.10.008
Antonino Costanzo , Alessandro Musetti , Rodolfo Rossi , Adriano Schimmenti
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引用次数: 0
Determinism of formamide-based biogenic prebiotic reactions 甲酰胺类生物源生物反应的决定性。
IF 13.7 1区 生物学 Q1 BIOLOGY
Physics of Life Reviews
Pub Date : 2024-10-16 DOI: 10.1016/j.plrev.2024.10.004
Raffaele Saladino, Bruno Mattia Bizzarri, Ernesto Di Mauro
Formamide reacted in the presence of a catalyst and of a source of energy affords a rich and complex panel of compounds, including amino acids, amino sugars, nucleic bases, nucleosides, carboxylic acids, aliphatic chains, and more. Nor the source of energy nor the type of catalyst are fastidious. All the catalysts tested have activity; each catalyst affords its own specific set of products, although the panels of products of each catalyst largely overlap. Potentially biogenic compounds form in reasonable conditions and the chemistry that determines the initial syntheses is facile. Hence, Darwins warm little pond did not rely on exotic environments nor on magic tricks. The type of molecules resulting from a mixture of formamide and of two selected products of its initial reactions hint that the initial prebiotic soup was deterministic and oriented towards life-as-we-know-it.
甲酰胺在催化剂和能量源的存在下发生反应，可产生丰富而复杂的化合物，包括氨基酸、氨基糖、核酸、核苷、羧酸、脂肪链等。对能量来源和催化剂类型的要求都不严格。所有测试过的催化剂都具有活性；每种催化剂都能提供自己特定的一组产物，尽管每种催化剂的产物板在很大程度上是重叠的。潜在的生物化合物在合理的条件下形成，决定初始合成的化学反应也很简单。因此，达尔文温暖的小池塘并不依赖于奇异的环境或魔术。甲酰胺和其初始反应的两种精选产物的混合物所产生的分子类型暗示，最初的前生物汤是确定性的，是面向我们所知的生命的。
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引用次数: 0
A technical comment on “A decade of thermostatted kinetic theory models for complex active matter living systems”. New fascinating perspectives of research 关于 "复杂活性物质生命系统恒温动力学理论模型的十年 "的技术评论。引人入胜的研究新视角
IF 13.7 1区 生物学 Q1 BIOLOGY
Physics of Life Reviews
Pub Date : 2024-10-11 DOI: 10.1016/j.plrev.2024.10.002
Massimiliano Ferrara
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引用次数: 0
The emotional grounds of existence: A phenomenologist's view. Commentary to “The affective grounds of the mind. The affective pertinentization (APER) model” by Salvatore et al. 存在的情感基础：现象学家的观点。对萨尔瓦多等人所著 "心灵的情感基础：情感相关化（APER）模型 "的评论。情感相关化（APER）模型 "的评论。
IF 13.7 1区 生物学 Q1 BIOLOGY
Physics of Life Reviews
Pub Date : 2024-10-10 DOI: 10.1016/j.plrev.2024.10.001
Giovanni Stanghellini
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引用次数: 0
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