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Mobile forensic photogrammetry in the field: Conservative approach to non-collaborative surfaces 实地移动法医摄影测量:非协作表面的保守方法
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2024-05-22 DOI: 10.1016/j.fri.2024.200597
Wolf Schweitzer , Haruki Fukuda , Michael Thali , Stephan Bolliger , Lars Ebert

Conventional photogrammetry faces challenges with non-textured, transparent, or reflective surfaces, affecting accurate 3D modeling, particularly in forensic documentation. This study evaluates improvements using lower exposure, exposure bracketing, and RAW format for better 3D modeling of non-textured surfaces. Two bodies were photographed under controlled conditions to assess techniques for non-textured surfaces, with a comparison set for textured surfaces. The experiments were conducted in an autopsy room with a Nikon D5500 camera, adjusting for low exposure, exposure bracketing, RAW format, and increased photo redundancy. Models with Meshroom (Alicevision). Our focus was on visual plausibility rather than quantitative metrics. Results indicated that using RAW format with exposure bracketing and low exposure significantly improved 3D models by reducing artificial edges seen with standard JPG images, despite some noise. A redundant series of RAW photos further reduced edge artifacts and noise, demonstrating the effectiveness of averaging photos to enhance model quality. However, these modifications showed marginal improvements on textured surfaces, underscoring their significant benefits primarily for non-textured surfaces. This study highlights the potential of modified photogrammetry techniques in forensic science, particularly for documenting challenging surfaces. It points out the need for further research, given its limitations in sample size and the absence of extensive parameter testing and quantitative analysis.

传统摄影测量在处理无纹理、透明或反光表面时面临挑战,影响了三维建模的准确性,特别是在法医文件中。本研究评估了使用较低曝光、曝光包围和 RAW 格式的改进措施,以便更好地对无纹理表面进行 3D 建模。在受控条件下拍摄了两具尸体,以评估针对非纹理表面的技术,并对纹理表面进行了对比。实验在解剖室进行,使用尼康 D5500 相机,调整为低曝光、曝光包围、RAW 格式并增加照片冗余度。使用 Meshroom(Alicevision)制作模型。我们的重点是视觉可信度,而不是量化指标。结果表明,尽管存在一些噪点,但使用 RAW 格式、曝光定标和低曝光可以减少标准 JPG 图像中出现的人为边缘,从而显著改善 3D 模型。一系列冗余的 RAW 照片进一步减少了边缘伪影和噪点,证明了平均照片对提高模型质量的有效性。不过,这些修改对纹理表面的改善微乎其微,主要对非纹理表面有显著优势。这项研究强调了改良摄影测量技术在法医学中的潜力,特别是在记录具有挑战性的表面时。鉴于样本量的限制以及缺乏广泛的参数测试和定量分析,本研究指出了进一步研究的必要性。
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引用次数: 0
Sex estimation from mandibular morphometry using discriminant analysis–CT scan based retrospective study 利用判别分析从下颌骨形态估计性别--基于 CT 扫描的回顾性研究
IF 0.8 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2024-07-05 DOI: 10.1016/j.fri.2024.200603
Vasanth Lenin , Siddhartha Das , Sunitha V․C․ , Sachit Ganapathy , Prachi Parinita Sahoo

It is well known that skeletal characteristics vary among different populations. Sex dimorphic characteristics of the mandible have been reported from studies using either mandible bone or computer tomography (CT) scan images of the mandible to test its efficacy in estimating sex. Mandibular studies for estimating sex in any particular population group may not hold well for different populations owing to inherent geographical variations. With this background, we assessed the validity of mandible measurements from CT scan images to determine sex in the South Indian population. As a part of our study, 11 metric parameters and 1 angular parameter were measured and analyzed. The mean values of all the parameters were significantly higher for males as compared to females. Bigonial breadth indicated the best discriminatory ability of the study. Mandibular angle had the least predictive accuracy among all the discriminant functions studied. We further observed that a combination of parameters gave the best overall classification rate (92.3 %). When the same functions were tested on an independent testing data set, a combination of parameters and bigonial breadth gave the best classification rate (82.1 %) which was consistent. We concluded that the mandible has a high accuracy for sex estimation. All the parameters studied demonstrated statistically significant differences between the two sexes except the mandibular angle.

众所周知,不同人群的骨骼特征各不相同。有研究报告称,下颌骨的性别二形特征是利用下颌骨或下颌骨计算机断层扫描(CT)图像来测试其在估计性别方面的有效性。由于固有的地域差异,用于估计特定人群性别的下颌骨研究可能不适用于不同人群。在此背景下,我们评估了通过 CT 扫描图像测量下颌骨来确定南印度人群性别的有效性。作为研究的一部分,我们测量并分析了 11 个度量参数和 1 个角度参数。男性所有参数的平均值都明显高于女性。大牙面宽显示了该研究的最佳判别能力。在所有研究的判别函数中,下颌角的预测准确性最低。我们进一步观察到,参数组合的总体分类率最高(92.3%)。在一个独立的测试数据集上测试相同的函数时,参数和大颚宽度的组合给出了最佳的分类率(82.1%),这是一致的。我们的结论是,下颌骨在性别估计方面具有很高的准确性。除下颌角外,所研究的所有参数在统计学上都显示出两种性别之间的显著差异。
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引用次数: 0
Analysis of the phenomenon of subdural hematoma observed in postmortem computed tomography disappearing at autopsy 对尸检计算机断层扫描中观察到的硬膜下血肿在尸检时消失现象的分析
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2024-06-10 DOI: 10.1016/j.fri.2024.200600
Nami Tsurushiin , Kazuhiko Kibayashi , Ryo Shimada , Ken-ichiro Nakao

Objectives

We encountered a case in which an acute subdural hematoma (SDH) was observed on postmortem computed tomography (PMCT) but no hematoma was found under the dura mater during autopsy. Subsequent verification led to the conclusion that the SDH was pressing on the brain when PMCT was performed but was not observed because all the subdural blood drained out during craniotomy because the hematoma did not clot.

Materials and Methods

We examined 13 cases of SDH in which PMCT was performed before autopsy to determine the factors related to the presence or absence of blood clots in the SDH, and to determine whether PMCT before autopsy could determine the presence or absence of blood clots in the SDH.

Results

Blood clots were not found in the SDH of individuals with an estimated survival interval of 5 h or less or when the estimated survival interval was 1440 h or more. No particular trend was observed in the relationship between the presence or absence of clots in the SDH and HU values of the SDH.

Conclusion

Early death after injury and chronic SDH are thought not to contain SDH clots. In cases of early death after injury, the autopsy diagnosis of SDH should be made by careful observation of the fluid SDH during craniotomy, as SDH may not contain clots as an indicator of SDH at autopsy. Predicting the presence or absence of a clot within an SDH using PMCT is difficult.

目标我们遇到过这样一个病例,即死后计算机断层扫描(PMCT)观察到急性硬膜下血肿(SDH),但尸检时却没有在硬脑膜下发现血肿。后来经过核实,得出的结论是:在进行 PMCT 时,硬膜下血肿压迫了大脑,但由于血肿没有凝固,在开颅手术中硬膜下的血液全部排出,因此没有观察到 SDH。材料与方法我们研究了13例在尸检前进行了PMCT的SDH病例,以确定与SDH中是否存在血凝块有关的因素,并确定尸检前的PMCT是否能确定SDH中是否存在血凝块。SDH中是否存在血凝块与SDH的HU值之间的关系没有特别的趋势。在损伤后早期死亡的病例中,尸检诊断 SDH 时应仔细观察开颅手术中的液性 SDH,因为尸检时 SDH 中可能不包含作为 SDH 指征的血凝块。使用 PMCT 预测 SDH 中是否存在血凝块很困难。
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引用次数: 0
The influence of the body position during PMCT: Implications for 3D reconstructions PMCT 期间身体位置的影响:对三维重建的意义
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-06-01 Epub Date: 2024-03-29 DOI: 10.1016/j.fri.2024.200589
Conrad Uldall Becker Schultz, Christina Jacobsen, Chiara Villa

Objectives

variations in the positions of organs and bones resulting from two different body positions during PMCT were investigated.

Methodology

Forty-four bodies were CT-scanned in two positions and compared using 18 landmarks and 27 distances.

Results and conclusion

Differences below 1 cm were observed for all measurements. The most significant variation was observed along the cranio-caudal plan (z). Awareness of these movements is important when using 3D models for visualization or 3D reconstructions.

结果和结论所有测量值的差异均低于 1 厘米。沿头颅-尾椎平面(z)观察到的差异最大。在使用三维模型进行可视化或三维重建时,意识到这些移动非常重要。
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引用次数: 0
Reduction methods for finger irradiation doses in mass disasters: A comparative study 减少大规模灾难中手指辐照剂量的方法:比较研究
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-06-01 Epub Date: 2024-04-22 DOI: 10.1016/j.fri.2024.200594
Atsushi Iwawaki , Yusei Otaka , Takeru Ishii , Akihiro Ochiai , Shinji Kito , Hideki Saka

Purpose

Since many intraoral radiographs are taken in mass disasters, it is important to reduce the finger irradiation dose to the operator and caregivers in intraoral radiography. However, there is not enough reporting on finger irradiation doses when the detector is placed in the oral cavity of a corpse. The objective of this study was to examine finger irradiation doses when using detector holders and protective gloves and to compare various reduction methods.

Methods

One type of disposable and two types of protective gloves were employed in this study. The average irradiation dose was calculated by dividing the accumulated dose by the number of irradiation events for intraoral imaging of the left mandibular molar; since the dosimeter detects a cumulative dose, irradiation was continued until the dose exceeded 100 μSv. Statistical analysis was performed using one-way analysis of variance, Bonferroni test, and multiple comparisons test (α = 0.05).

Results

A significant dose reduction was observed using protective gloves (maximum: 63%, mean: 59%; p<0.01). No significant difference in the irradiation dose to the finger was observed when disposable gloves were layered on protective gloves. When protective gloves were used with the detector holder held at the end position, the radiation dose reduced by approximately 91% compared to when the detector was held directly in the oral cavity. Implementing these radioprotective measures can reduce the risks of increased radiation exposure and contamination.

Conclusions

The combined use of detector holders and protective gloves was effective in reducing the radiation exposure to the operator's fingers.

目的由于在大规模灾难中会拍摄许多口腔内放射照片,因此在口腔内放射摄影中减少操作者和护理人员的手指辐射剂量非常重要。然而,关于将探测器放置在尸体口腔内时手指辐照剂量的报道并不多。本研究的目的是检测使用探测器支架和防护手套时的手指辐照剂量,并比较各种减少剂量的方法。平均辐照剂量的计算方法是:左下颌臼齿口内成像的累积剂量除以辐照次数;由于剂量计检测的是累积剂量,因此辐照一直持续到剂量超过 100 μSv 为止。统计分析采用单因素方差分析、Bonferroni 检验和多重比较检验(α = 0.05)。将一次性手套叠加在防护手套上时,手指受到的辐照剂量没有明显差异。当使用防护手套并将探测器支架放在末端位置时,与直接将探测器放在口腔中相比,辐射剂量减少了约 91%。结论 联合使用探测器支架和防护手套可有效减少操作员手指受到的辐射照射。
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引用次数: 0
Effects of water and other filters on fracture resolution in industrial micro-CT scanning 水和其他过滤器对工业显微 CT 扫描中断口分辨率的影响
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-06-01 Epub Date: 2024-03-20 DOI: 10.1016/j.fri.2024.200588
Mary R. Mani, Angi M. Christensen, Amani Rafiq

Filtering is known to improve image quality of CT scans. Water immersion is one type of filtering that has been used for CT scanning dry (skeletonized) bones, and it has been suggested that this approach can increase measurement accuracy and improve fracture resolution. These tests have previously involved clinical CT scanners. Here we use an industrial micro-CT scanner and test whether water immersion and other x-ray filtering options increases fracture resolution in reconstructed scans of dry bones.

Eleven dry non-human bones were CT scanned using the same acquisition parameters, while varying filter options. Bones were scanned (1) in an unfiltered “dry” air environment, (2) using metal filters at the x-ray source, and (3) with the bones immersed in water. A small subset of bones (N = 3) was also scanned using the same parameters except increasing the number of projections acquired from 500 to 1500. Reconstructed scans were evaluated by the authors, in part using a Likert scale comparing filtered with unfiltered scans, to assess fracture resolution (overall appearance and extent).

Results showed that increasing the projections resulted in the greatest improvement in fracture resolution, followed by filtering at the x-ray source. Water immersion performed poorly overall, possibly due to movement artifacts that result from this type of scanning, in which the specimen rotates on a stage during the scan. When using this type of CT scanner, if increased fracture resolution is desired, water immersion is not recommended; increasing the number of projections or filtering at the x-ray source is suggested instead.

众所周知,滤波可提高 CT 扫描的图像质量。水浸是一种过滤方法,已被用于 CT 扫描干燥(骨骼化)的骨骼,有人认为这种方法可以提高测量精度和骨折分辨率。这些测试以前都是在临床 CT 扫描仪上进行的。在这里,我们使用一台工业用微型 CT 扫描仪,测试水浸泡和其他 X 射线过滤选项是否能提高干骨重建扫描的骨折分辨率。对这些骨骼进行了以下扫描:(1) 在未经过滤的 "干燥 "空气环境中;(2) 在 X 射线源处使用金属过滤器;(3) 将骨骼浸泡在水中。对一小部分骨骼(N = 3)也使用相同的参数进行扫描,只是将获取的投影次数从 500 增加到 1500。结果显示,增加投影次数对骨折分辨率的改善最大,其次是在 X 射线源处进行过滤。水浸法的整体表现较差,这可能是由于这种扫描方式在扫描过程中标本在平台上旋转而产生的运动伪影。在使用这种 CT 扫描仪时,如果希望提高骨折分辨率,不建议使用水浸法;建议增加投影次数或在 X 射线源处进行过滤。
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引用次数: 0
Estimating South African socio-cultural identity using sub-specific discriminate 3D shape matrices 利用亚特定判别三维形状矩阵估算南非社会文化特征
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-06-01 Epub Date: 2024-04-08 DOI: 10.1016/j.fri.2024.200591
Alison Fany Ridel, Ericka Noelle L'Abbé

In forensic anthropology, the probable identification of an unknown individual is based on the presence of quantifiable phenotypic variations and the relationship of these variations to the individual's socio-cultural identity. This study aims to create sub-specific discriminate shape matrices to estimate socio-cultural identity among a modern black South African sample, with a particular emphasis on developing standards for predicting mid-facial variation within this population.

The sample consists of 191 adult South Africans representing nine modern black South African socio-cultural identity groups obtained from the Pretoria Bone Collection in the Department of Anatomy at the University of Pretoria. Three-dimensional (3D) modelling of the relevant anatomical area was performed using an EinScan H 3D scanner. The 3D anatomical extraction was performed by placing 37 standard craniometric landmarks and 388 sliding landmarks on 3D models.

The analysis of variance associated with the linear model “shape against socio-cultural identity” explained 95.5% of overall shape variation showed that variations in midfacial shape configurations were statistically significant (MANOVA: p= 0.001; 50-50 MANOVA: p <2e-16) for all shape configurations, including sub-specific discriminate shape matrices, separately. Additionally, cross-validated linear discriminant function analysis yielded an accuracy between 73.01% and 91.53% for all shape configurations and sub-specific discriminant shape matrices, reflecting the discriminative power of socio-cultural identity groups in the black South African population.

Our findings support the utilization of geometric morphometric methods (GMM) for socio-cultural identity estimation as they allow us to retain the objects' geometry and statistically analyze subtle structural differences.

在法医人类学中,未知个体的可能身份识别是基于是否存在可量化的表型变异以及这些变异与个体社会文化身份的关系。本研究旨在创建亚特异性辨别形状矩阵,以估计现代南非黑人样本中的社会文化身份,特别强调制定预测该人群面部中部变异的标准。样本由 191 名成年南非人组成,代表九个现代南非黑人社会文化身份群体,这些样本来自比勒陀利亚大学解剖学系的比勒陀利亚骨骼收藏。使用 EinScan H 三维扫描仪对相关解剖区域进行了三维建模。三维解剖提取是通过在三维模型上放置 37 个标准颅骨测量地标和 388 个滑动地标来完成的。与 "形状与社会文化身份 "线性模型相关的方差分析解释了 95.5% 的整体形状变化,结果显示,中面部形状配置的变化对所有形状配置(包括亚特异性判别形状矩阵)分别具有显著的统计学意义(MANOVA:p= 0.001;50-50 MANOVA:p <2e-16)。此外,通过交叉验证线性判别函数分析,所有形状配置和亚特定判别形状矩阵的准确率介于 73.01% 和 91.53% 之间,反映了南非黑人社会文化身份群体的判别能力。我们的研究结果支持将几何形态计量方法 (GMM) 用于社会文化身份估计,因为它们允许我们保留对象的几何形状,并对细微的结构差异进行统计分析。
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引用次数: 0
Cranial measurements obtained by three-dimensional computed tomography technique in the estimation of sex of contemporary Black South Africans 通过三维计算机断层扫描技术获得的颅骨测量结果用于估计当代南非黑人的性别
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-06-01 Epub Date: 2024-03-08 DOI: 10.1016/j.fri.2024.200585
Oriasotie M Ujaddughe , Jenny Haberfeld , Mubarak A Bidmos , Oladiran I Olateju

Human identification forms an integral part of forensic and biological anthropology. For proper identification, a biological profile made up of biodata such as age, sex, ancestry, antemortem stature, and factors of individualization, is obtained and stored for use by anthropologists. A correct sex estimation can help unravel other anthropological parameters. South Africa has a multi-dimensionally high crime rate and its largest distinct population group (Black South Africans) is most affected by such crimes. Several authors have in the past used cranial measurements to carry out sex discrimination among South Africans, such attempts have largely been done using direct assessment of post-mortem specimens and on subjects of European Descent. This study, therefore, attempted to overcome these drawbacks by using a non-invasive method, the three-dimensional computed tomography (3DCT) to obtain population-specific data from a contemporary Black South African population group. It obtained measurements from cranial CT records of 350 Black South Africans (50 % sex ratio) housed in the Radiology Department of Charlotte Maxeke Johannesburg Academic Hospital. The Xiris and IntelliSpace software were used to reconstruct the images into three-dimensional forms from which measurements were taken. Evaluation of previously derived equations using data from the current study yielded low average classification accuracies which necessitated the formulation of new equations. Discriminant function analysis yielded acceptably high average classification accuracies for sex estimation which ranged from 78.3 % to 82.9 %.

人体识别是法医和生物人类学的一个组成部分。为了进行正确的身份识别,人类学家需要获得并储存由年龄、性别、祖先、死前身材和个体化因素等生物数据组成的生物档案。正确的性别估计有助于揭示其他人类学参数。南非的犯罪率多方面都很高,其最大的独特人口群体(南非黑人)受此类犯罪的影响最大。过去曾有几位学者利用颅骨测量来对南非人进行性别鉴别,但这些尝试主要是通过对死后标本和欧洲后裔受试者进行直接评估来完成的。因此,本研究试图利用一种非侵入性方法--三维计算机断层扫描(3DCT)--从当代南非黑人群体中获取特定人群的数据,从而克服这些缺点。它从夏洛特-麦克斯克约翰内斯堡学术医院放射科的 350 名南非黑人(性别比为 50%)的头颅 CT 记录中获得了测量数据。Xiris 和 IntelliSpace 软件用于将图像重建为三维形式,并据此进行测量。使用本次研究的数据对之前得出的公式进行评估后发现,平均分类准确率较低,因此有必要制定新的公式。判别函数分析得出的性别估计平均分类准确率较高,从 78.3% 到 82.9% 不等。
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引用次数: 0
Development of a technique for postmortem CT angiography of fetuses with a lipophilic contrast agent 利用亲脂性造影剂开发胎儿死后 CT 血管造影技术
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-06-01 Epub Date: 2024-04-20 DOI: 10.1016/j.fri.2024.200593
Jessica Vanhaebost , Nicolas Michoux , Xavier de Spiegeleire , Silke Grabherr , Emmanuel Coche

Background and objectives

Postmortem examinations of fetuses play a crucial role in confirming abnormalities, especially vascular and cardiac malformations leading to fetal demise. This study aims at developing and assessing a method for acquiring Post-Mortem CT-Angiography (PMCTA) with the injection of a lipophilic contrast agent (CA) to better visualize the great vessels of the trunk and head.

Materials and methods

25 human fetuses (gestational age at death between 106 days and 28 weeks) were included. Examinations were performed using a dual-energy Multidetector Computed Tomography (MDCT) scanner. Three imaging sequences were acquired, before CA injection, after injection of 7mL of CA through umbilical artery (arterial phase), and after an injection of 15mL of CA through umbilical vein (venous phase). CA-induced vascular opacification was scored per-vessel in both phases as follows: 0 = none, 1 = partial, 2 = complete. Total opacification was defined as the sum of the per-vessel opacification scores.

Results

In 23/25 subjects, CA injection into the umbilical vessels was feasible manually using flexible catheters. After the first injection, at least a partial opacification of the arterial network was achieved in 15/23 (65%) subjects. After the second injection, a complete opacification of the venous network was achieved in 18/23 (78%) subjects. Failures occurred in 10/25 (40%) subjects and were mostly due to the preservation status.

Conclusion

PMCTA performed with a two-phase intra-umbilical injection of a lipophilic CA enabled to visualize the vascular network, even after a significant a postmortem interval. This protocol may help in detecting vascular malformations, improving clinical diagnoses and prenatal counselling.

背景和目的 胎儿死后检查在确认畸形,尤其是导致胎儿死亡的血管和心脏畸形方面起着至关重要的作用。本研究旨在开发和评估一种通过注射亲脂性造影剂(CA)获取死后 CT-血管造影(PMCTA)的方法,以更好地观察躯干和头部的大血管。检查使用双能量多载体计算机断层扫描(MDCT)扫描仪进行。分别在注射CA前、通过脐动脉注射7毫升CA后(动脉期)和通过脐静脉注射15毫升CA后(静脉期)采集三个成像序列。在这两个阶段中,每个血管的 CA 诱导血管不透明评分如下:0 = 无,1 = 部分,2 = 完全。结果 在 23/25 名受试者中,可以使用柔性导管手动向脐血管注射 CA。第一次注射后,15/23(65%)名受试者的动脉网络至少实现了部分不透明。第二次注射后,18/23(78%)名受试者的静脉网络实现了完全透明化。10/25 例受试者(40%)出现了失败,主要是由于保存状态造成的。结论 通过脐内两阶段注射亲脂 CA 进行的 PMCTA 能够观察到血管网络,即使是在死后间隔了很长时间之后。该方案有助于检测血管畸形,改善临床诊断和产前咨询。
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引用次数: 0
Bone mineral density measurements in postmortem computed tomography: An open-source approach 死后计算机断层扫描中的骨矿物质密度测量:一种开源方法
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-06-01 Epub Date: 2024-03-18 DOI: 10.1016/j.fri.2024.200586
Kasper Hansen , Dennis Vinther , Lene Warner Thorup Boel , Gülislam Ağacan , Jesper Thygesen , Lars Uhrenholt , Henrik Lauridsen

Objectives

In quantitative postmortem computed tomography (qPMCT) the presence of putrefaction gas in tissues can obscure measurements such as bone mineral density (BMD). Quantitative CT analysis procedures adopted directly from clinical CT may not be designed to compensate for intracorporeal gas, which require additional measures for PM-imaging applications. Thus, a solid unbiased procedure for volumetric BMD analysis in PMCT of the deceased presenting with intracorporeal gas is desirable.

Materials and methods

We tested three different analysis procedures (AP1-3) for BMD analysis of the lumbar vertebrae (L1-3). Data in this retrospective study was based on synchronous PMCT acquisition with a solid five-phase Cann-Genant phantom from routine forensic examinations of 154 individuals distributed into three putrefaction groups: “None” (n = 95), “Mild” (n = 54), and “Moderate” (n = 10). AP1 was based on commercially available software (“Mindways”), which required the operator to subjectively place region of interest (ROIs) in areas without gas. The open-source software (“FIJI”) was used for AP2 and AP3 and enabled comparison of objectively placed ROIs with AP1. In AP3, threshold-filtering was applied to remove the signal from gas (in AP2 data) prior to BMD analysis.

Results

AP1 provided higher BMD values than AP2-3 due to subjective placement of ROIs in denser cortical areas. AP2 yielded the lowest BMD measurements with most variation, while AP3 yielded BMD measurements comparable to in vivo values published in clinical studies. AP3 provided greater interobserver correlation.

Conclusion

AP3 provided a simple open-source software-based approach to PMCT BMD analysis that allows for precise BMD measurements in PMCT.

目的在尸体定量计算机断层扫描(qPMCT)中,组织中存在的腐败气体会掩盖骨矿物质密度(BMD)等测量结果。直接从临床 CT 采用的定量 CT 分析程序可能无法弥补体腔内气体,这就需要在 PM 成像应用中采取额外措施。因此,我们需要一种可靠、无偏见的程序,用于对存在体外气体的死者进行 PMCT 体积 BMD 分析。材料与方法 我们测试了三种不同的分析程序(AP1-3),用于分析腰椎(L1-3)的 BMD。这项回顾性研究的数据是基于对 154 人进行的常规法医检查得出的同步 PMCT 采集结果,这些人被分为三个腐烂组,分别是:"无"(n = 95)、"有"(n = 95)和 "无"(n = 95):无"(95 人)、"轻度"(54 人)和 "中度"(10 人)。AP1 基于市售软件("Mindways"),要求操作员主观地将感兴趣区(ROI)置于无气体区域。AP2 和 AP3 使用的是开源软件("FIJI"),可将客观放置的 ROI 与 AP1 进行比较。在 AP3 中,在进行 BMD 分析之前,应用了阈值滤波以去除气体信号(在 AP2 数据中)。结果 AP1 提供的 BMD 值高于 AP2-3,原因是主观地将 ROI 放置在皮质较致密的区域。AP2 得出的 BMD 测量值最低,差异最大,而 AP3 得出的 BMD 测量值与临床研究公布的体内值相当。结论AP3为PMCT BMD分析提供了一种基于开源软件的简单方法,可在PMCT中进行精确的BMD测量。
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Forensic Imaging
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