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1995 IEEE Nuclear Science Symposium and Medical Imaging Conference Record最新文献

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The column architecture-a novel architecture for event driven 2D pixel imagers 列架构——一种用于事件驱动的2D像素成像仪的新架构
Pub Date : 1995-10-21 DOI: 10.1109/NSSMIC.1995.504236
J. Millaud, D. Nygren
We describe an electronic architecture for two-dimensional pixel arrays that permits very large increases in rate capability for event- or data-driven applications relative to conventional x-y architectures. The column architecture also permits more efficient use of silicon area in applications requiring local buffering, frameless data acquisition, and it avoids entirely the problem of ambiguities that may arise in conventional approaches. Two examples of active implementation are described: high energy physics and protein crystallography.
我们描述了一种二维像素阵列的电子架构,相对于传统的x-y架构,它允许事件或数据驱动应用程序的速率能力大幅提高。列架构还允许在需要本地缓冲、无帧数据采集的应用程序中更有效地使用硅面积,并且它完全避免了传统方法中可能出现的歧义问题。描述了两个主动实现的例子:高能物理和蛋白质晶体学。
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引用次数: 15
Simple charge division readouts for imaging scintillator arrays using a multi-channel PMT 使用多通道PMT成像闪烁体阵列的简单电荷划分读出
Pub Date : 1995-10-21 DOI: 10.1109/NSSMIC.1995.504167
S. Siegel, R. Silverman, Y. Shao, S. Cherry
Three simple charge division circuits were assembled, and tested, as 2-D readouts for multi-channel photomultiplier tubes (MC-PMT). They were evaluated with an 8/spl times/8 array of individual scintillators (2/spl times/2/spl times/10 mm BGO) coupled to a 64 channel MC-PMT (Philips XP1722) via 25 cm long, 2 mm diameter, double clad, optical fibers (Kuraray). This type of /spl gamma/-ray imaging detector has many potential applications in medical and industrial imaging. Independent channel readout allows for the discrimination of scatter within the array, and higher count rates, but it requires an excessive amount of supporting electronics. This is specially true for multi-array imaging systems with hundreds, or thousands, of channels. In this study, the number of channels being read out was reduced from 64 to 4. This was achieved by the use of simple resistor networks which take advantage of the discretized nature of the scintillator array, the low crosstalk of the MC-PMT and low input impedance current-sensitive preamplifiers. For each circuit, the scintillator identification accuracy was compared. The identification accuracy as a function of deposited energy was also determined by exposure to various /spl gamma/ emitters. It was found that the preamplifier circuit noise contributed the most to the degradation of the detector's spatial response so several low noise op amps were evaluated. It was also determined that keeping the preamplifier input impedance small was necessary for accurate positioning. The timing resolution of the detector was slightly degraded by the readout circuit.
组装了三个简单的电荷划分电路,并测试了它们作为多通道光电倍增管(MC-PMT)的二维读数。通过长25厘米、直径2毫米的双包层光纤(Kuraray),将单个闪烁体的8/spl倍/8阵列(2/spl倍/2/spl倍/10毫米BGO)耦合到64通道MC-PMT (Philips XP1722)上。这种类型的/spl伽马/射线成像探测器在医疗和工业成像中有许多潜在的应用。独立的通道读出允许阵列内散射的辨别和更高的计数率,但它需要过多的支持电子设备。对于具有数百或数千通道的多阵列成像系统尤其如此。在本研究中,读出的通道数从64个减少到4个。这是通过使用简单的电阻网络来实现的,该网络利用了闪烁体阵列的离散特性、MC-PMT的低串扰和低输入阻抗电流敏感前置放大器。对每个电路的闪烁体识别精度进行了比较。识别精度作为沉积能量的函数也确定了暴露于各种/spl γ /发射器。研究发现前置放大器电路噪声对探测器空间响应的影响最大,因此对几种低噪声运放进行了评价。还确定保持前置放大器输入阻抗小是精确定位的必要条件。读出电路使检测器的时序分辨率略有降低。
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引用次数: 303
Monte Carlo modeling of coherent scattering: influence of interference 相干散射的蒙特卡罗模拟:干涉的影响
Pub Date : 1995-10-21 DOI: 10.1109/NSSMIC.1995.500320
C. J. Leliveld, J. Maas, V. Bom, C. V. van Eijk
In this study, the authors present Monte Carlo (MC) simulation results for the intensity and angular distribution of scattered radiation from cylindrical absorbers. For coherent scattering the authors have taken into account the effects of interference by using new molecular form factor data for the AAPM plastic materials and water. The form factor data were compiled from X-ray diffraction measurements. The new data have been implemented in the authors' Electron Gamma Shower (EGS4) Monte Carlo system. The hybrid MC simulation results show a significant influence on the intensity and the angular distribution of coherently scattered photons. It is concluded that MC calculations are significantly in error when interference effects are ignored in the model for coherent scattering. Especially for simulation studies of scattered radiation in collimated geometries, where small angle scattering will prevail, the coherent scatter contribution is highly overestimated when conventional form factor data are used.
本文用蒙特卡罗(MC)方法模拟了圆柱形吸收体散射辐射的强度和角分布。对于相干散射,作者利用新的AAPM塑料材料和水的分子形状因子数据考虑了干扰的影响。形状因子数据是从x射线衍射测量中编译的。新数据已在作者的电子伽马雨(EGS4)蒙特卡罗系统中实现。混合MC模拟结果表明,混合MC对相干散射光子的强度和角分布有显著影响。结果表明,在相干散射模型中忽略干涉效应时,MC计算误差较大。特别是对于准直几何散射辐射的模拟研究,其中小角度散射将占上风,当使用传统的形状因子数据时,相干散射贡献被高度高估。
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引用次数: 33
Design of automated algorithms for analyzing gated SPECT cardiac blood pool images 门控SPECT心脏血池图像自动分析算法设计
Pub Date : 1995-10-21 DOI: 10.1109/NSSMIC.1995.500273
T. Hebert, W. Moore, R. Dhekne, P. Ford, J. Wendt, P. Murphy
The design of automated computer algorithms for delineating the left and right ventricular regions within gated 3-D reconstructions of the cardiac blood pool is investigated. Due to patient functional abnormalities, limited resolution, and noise, certain spatial and temporal features of the cardiac blood pool that one would anticipate finding in every study are not present in certain frames or with certain patients. Therefore, the labeling of the chambers of the cardiac blood pool requires an algorithm that only relies upon features present in all patients. We examine a sequential algorithm wherein the limiting factor in the accuracy and reliability of the algorithm is that of locating the atrio-ventricular valve planes.
研究了在门控心脏血池三维重建中描述左、右心室区域的自动计算机算法的设计。由于患者功能异常、分辨率有限和噪声,在每项研究中预期发现的心脏血池的某些空间和时间特征在某些框架或某些患者中并不存在。因此,心脏血池腔室的标记需要一种仅依赖于所有患者存在的特征的算法。我们研究了一种顺序算法,其中算法的准确性和可靠性的限制因素是定位房室瓣膜平面。
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引用次数: 0
A NRC perspective on the revised 10 CFR part 21 rule for the procurement of commercial digital computer systems for use in safety system applications in nuclear power facilities 美国核管理委员会对采购用于核能设施安全系统应用的商用数字计算机系统的修订后10 CFR第21部分规则的看法
Pub Date : 1995-10-21 DOI: 10.1109/NSSMIC.1995.510417
J. C. Stewart, R. C. Wilson
The use of commercially available digital computer systems and components in safety critical systems (nuclear power plant, military, and commercial applications) is increasing rapidly. Commercial dedication (the process of assuring that a commercial grade item will perform its intended safety function) has demonstrated benefits in cost savings and a wide base of user experience, however, care must be taken to avoid difficulties with some aspects of the dedication process such as access to vendor development information, configuration management, long term support, and system integration.
在安全关键系统(核电站、军事和商业应用)中,商用数字计算机系统和组件的使用正在迅速增加。商业专用(确保商业级产品将执行其预期的安全功能的过程)在节省成本和广泛的用户体验方面已经证明了好处,但是,必须注意避免专用过程中某些方面的困难,例如访问供应商开发信息、配置管理、长期支持和系统集成。
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引用次数: 0
Correction of organ motion in SPECT using reprojection data 用重投影数据校正SPECT中的器官运动
Pub Date : 1995-10-21 DOI: 10.1109/NSSMIC.1995.500301
L. Arata, P. H. Pretorius, M. King
Organ motion during SPECT acquisition can cause artifacts in the reconstructed slices which may affect the clinical interpretation. A new algorithm is presented which corrects for translational organ motion in SPECT projection data and thus reduces the resulting artifacts. The projection data is first reconstructed and then reprojected to the original angles. These reprojection data provide a template for comparison with the true projection data to estimate motion. An organ of interest is selected interactively using a count threshold on the reconstructed slices. From this, regions of interest are reprojected and used to limit the region of comparison and improve efficiency. Parabolic interpolation is used to interpolate fractional shifts. The algorithm corrects for translational motion in the projection data along both X and Y axes. The algorithm was evaluated using point sources in air with physical motion induced during acquisition and artificially induced motion using Monte Carlo simulated MCAT phantom data. Results show that the FWHM's and FWTM's of corrected point source data compare favorably with point source data without motion induced. Polar maps of the MCAT phantom clearly show the improvement after the correction was implemented. Further validation and clinical testing are in progress.
在SPECT采集过程中,器官运动可能会在重建的切片中产生伪影,从而影响临床解释。提出了一种新的算法,对SPECT投影数据中的平移器官运动进行校正,从而减少了产生的伪影。首先对投影数据进行重构,然后重新投影到原始角度。这些重投影数据为与真实投影数据的比较提供了一个模板来估计运动。在重建的切片上使用计数阈值交互式地选择感兴趣的器官。以此为基础,对感兴趣的区域进行重新投影,用于限制比较区域,提高效率。抛物线插值用于插值分数位移。该算法对沿X轴和Y轴投影数据中的平移运动进行校正。利用空气中的点源,在采集过程中诱导物理运动,并利用蒙特卡罗模拟MCAT幻影数据人工诱导运动,对该算法进行了评估。结果表明,与未引起运动的点源数据相比,校正后的点源数据的FWHM和FWTM均较好。MCAT幻像的极坐标图清楚地显示了校正后的改善。进一步的验证和临床试验正在进行中。
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引用次数: 29
Pixel frontend electronics in a radiation hard technology for hybrid and monolithic applications 用于混合和单片应用的辐射硬技术中的像素前端电子器件
Pub Date : 1995-10-21 DOI: 10.1109/NSSMIC.1995.510372
F. Pengg, M. Campbell, E. Heijne, W. Snoeys
Pixel detector readout cells have been designed in the radiation hard DMILL technology and their characteristics evaluated before and after irradiation to 14 Mrad. The test chip consists of two blocks of six readout cells each. Two different charge amplifiers are implemented, one of them using a capacitive feedback loop, the other the fast signal charge transfer to a high impedance integrating node. The measurements give the following results: the equivalent noise charge is 110e/sup -/ RMS (150e/sup -/ RMS after irradiation); at a threshold of 5000e/sup -/ (4000e(/sup -/)) the threshold variation is 300e/sup -/ RMS (250e/sup -/ RMS) and the time walk is 40 ns (40 ns). The use of this SOI technology for monolithic integration of electronics and detector in one substrate is under investigation.
在辐射硬DMILL技术中设计了像素探测器读出单元,并对其辐照至14mrad前后的特性进行了评价。测试芯片由两个模块组成,每个模块有六个读出单元。实现了两种不同的电荷放大器,其中一种使用电容反馈回路,另一种将快速信号电荷传输到高阻抗积分节点。测量结果如下:等效噪声负荷为110e/sup -/ RMS(辐照后为150e/sup -/ RMS);阈值为5000e/sup -/ (4000e(/sup -/))时,阈值变化为300e/sup -/ RMS (250e/sup -/ RMS),行走时间为40ns (40ns)。将这种SOI技术用于电子器件和探测器的单片集成,目前正在研究中。
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引用次数: 4
Radiation-induced surface leakage currents in silicon microstrip detectors 硅微带探测器中辐射诱发的表面泄漏电流
Pub Date : 1995-10-21 DOI: 10.1109/NSSMIC.1995.510365
A. Foland, J. Alexander
After exposure to X-rays and UV light, we have observed induced leakage currents in silicon microstrip detectors designed for CLEO III. UV measurements have shown that the damage is confined to the Si-SiO/sub 2/ interfacial area. The damage is manifested only as a leakage current without additional 1/f noise or significant changes to detector parameters. The scaled damage rate is measured to be 5/spl plusmn/1 nA/cm/sup 2//kRad for 20 keV X-rays.
在x射线和紫外光照射下,我们观察到了CLEO III型硅微带探测器的感应漏电流。紫外测量表明,损伤仅限于Si-SiO/sub - 2/界面区域。损坏仅表现为泄漏电流,没有额外的1/f噪声或检测器参数的显着变化。在20 keV的x射线中,测量到的比例损伤率为5/spl plusmn/1 nA/cm/sup 2//kRad。
{"title":"Radiation-induced surface leakage currents in silicon microstrip detectors","authors":"A. Foland, J. Alexander","doi":"10.1109/NSSMIC.1995.510365","DOIUrl":"https://doi.org/10.1109/NSSMIC.1995.510365","url":null,"abstract":"After exposure to X-rays and UV light, we have observed induced leakage currents in silicon microstrip detectors designed for CLEO III. UV measurements have shown that the damage is confined to the Si-SiO/sub 2/ interfacial area. The damage is manifested only as a leakage current without additional 1/f noise or significant changes to detector parameters. The scaled damage rate is measured to be 5/spl plusmn/1 nA/cm/sup 2//kRad for 20 keV X-rays.","PeriodicalId":409998,"journal":{"name":"1995 IEEE Nuclear Science Symposium and Medical Imaging Conference Record","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114513792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Initial results from the Sherbrooke avalanche photodiode PET scanner Sherbrooke雪崩光电二极管PET扫描仪的初步结果
Pub Date : 1995-10-21 DOI: 10.1109/NSSMIC.1995.500254
R. Lecomte, J. Cadorette, S. Rodrigue, D. Lapointe, D. Rouleau, M. Bentourkia, R. Yao, P. Msaki, G. Schmutz
The design features and engineering constraints of a PET system based on avalanche photodiode (APD) detectors have been described in a previous report. Here, the authors present the initial results obtained with the Sherbrooke APD-PET scanner, a very high spatial resolution device designed for dynamic imaging of small and medium-sized laboratory animals such as rats, cats, rabbits and small monkeys. Its physical performance have been evaluated in terms of resolution, sensitivity, count rate, random and scatter fractions, and activity recovery as a function of object size. The capabilities of the scanner for biomedical research applications have been demonstrated using phantom and animal studies.
基于雪崩光电二极管(APD)探测器的PET系统的设计特点和工程限制已经在之前的报告中描述过。在这里,作者介绍了Sherbrooke APD-PET扫描仪获得的初步结果,这是一种非常高空间分辨率的设备,专为中小型实验动物(如大鼠、猫、兔子和小猴子)的动态成像而设计。它的物理性能在分辨率、灵敏度、计数率、随机和分散分数以及作为物体大小的函数的活动恢复方面进行了评估。该扫描仪在生物医学研究中的应用能力已经通过幻影和动物研究得到了验证。
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引用次数: 5
Resolution characterization of continuous axial sampling in whole body PET 全身PET连续轴向采样的分辨率表征
Pub Date : 1995-10-21 DOI: 10.1109/NSSMIC.1995.510437
M. Dahlbom, A. Chatziioannou, C. Hoh
By acquiring whole body data at a large number of small axial positions, each equal to the transaxial plane separation, one can achieve a significant improvement in image quality. This improvement is attributed to the uniform axial sensitivity achieved by allowing each detector plane measure each axial data point. By moving the bed in a true continuous motion, instead of in discrete steps, one can achieve additional improvements in image quality by eliminating artifacts due to under-sampling in the axial direction. To investigate the properties of the continuous axial sampling, measurements and simulations of an ECAT EXACT HR PET system were performed. The axial resolution of this system is 3.5 mm at the center of the FOV and the axial sampling is approximately 3.1 mm. This system clearly undersamples axially and sampling artifacts were also seen in a hot spot phantom and bar patterns, imaged in the axial direction. By moving the bed continuously and sort the data into smaller bins (<1.6 mm) these sampling artifacts were virtually eliminated. Images acquired at a high sampling frequency had better image contrast and noise characteristics after spatial filtering compared to images with the same total number of counts but acquired at a low spatial frequency.
通过在大量小轴向位置获取全身数据,每个小轴向位置都等于跨轴平面分离,可以显著提高图像质量。这种改进归功于通过允许每个探测器平面测量每个轴向数据点而实现的均匀轴向灵敏度。通过在一个真正的连续运动中移动床,而不是在离散的步骤中,人们可以通过消除由于轴向采样不足而产生的伪影来实现图像质量的进一步改善。为了研究连续轴向取样的特性,对ECAT EXACT HR PET系统进行了测量和模拟。该系统的视场中心轴向分辨率为3.5 mm,轴向采样约为3.1 mm。该系统在轴向明显欠采样,并且在热点幻影和柱状图案中也可以看到采样伪影,在轴向成像。通过连续移动床并将数据分类到较小的箱中(<1.6 mm),这些采样伪影几乎被消除了。高采样频率下获得的图像经过空间滤波后的图像对比度和噪声特性优于低采样频率下获得的总采样次数相同的图像。
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引用次数: 7
期刊
1995 IEEE Nuclear Science Symposium and Medical Imaging Conference Record
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