Y. Sakho, F. Holden, N. Ndoye, M. Ba, Diene, S. Badiane, J. Dangou, F. Diouf, K. Dia, C. Seck
Objectifs Rapporter notre experience sur la chirurgie des meningiomes intracrâniens a Dakar . Methode Les auteurs rapportent une serie retrospective de 24 patients porteurs de meningiomes intracrâniens operes dans une unite neurochirurgicale differente de notre institution mere a Dakar . Le recrutement s'est fait de Janvier 2001 a Juillet 2004. L'evaluation diagnostique a repose essentiellement sur la tomodensitometrie cerebrale et l'anatomo-pathologie. Resultats Il s'agissait de 17 femmes et de 7 hommes. L'âge de nos patients variaient entre 21 et 77 ans avec un pic de frequence a 55 ans . Le syndrome d'hypertension intracrânienne et la comitialite ont ete les circonstances diagnostiques les plus frequentes avec un taux de 37%. La tomodensitometrie cerebrale a permis d'evoquer un diagnostic presomptif de nature. Concernant la topographie, les meningiomes de la convexite ont ete observes dans 50% des cas suivis par les meningiomes de la base (20%). L'evaluation de la qualite de l'exerese chirurgicale selon le grading de Simpson a retrouve 20% de grade I et 64% de grade II. L'insuffisance du plateau technique et le manque de competences en neuroanesthesie rendent compte de la mortalite post-operatoire de 12%. Conclusion Ce travail nous permet de proposer une strategie d'amelioration de la pratique neurochirurgicale tumorale en Afrique subsaharienne. Objective To report our experience of intracranial meningiomas surgery in Dakar. Method We analysed a population of 24 patients who underwent operation in a Neurosurgical unit different from our mother Institution. Brain CT scan has been done for every patient and histopathological confirmation has been reached for all patients. Results Regarding sex, we have 17 females for 7 males. The patient age was between 21 and 77 years old with a mean of 55.Intracranial hypertension and seizures were the main symptoms encountered with 37% for each. Our diagnostic evaluation is based on CT scan which showed 50% of convexity meningiomas and 20% basal one .By using Simpson grading to assess the quality of surgical resection ,we found 64% of grade II and only 20% of grade I.A 12% of postoperative death rate is related on the substandard medical set and the lack of neuroanesthesists. Conclusion We outlined a program to improve the neurosurgery practice in Sub-Saharan countries. Keywords : Afrique, meningiomes intracrâniens, neurochirurgie, Senegal, tumeurs, Africa, intracranial tumors, meningioma, neurosurgery, Senegal African Journal of Neurological Sciences Vol. 24 (1) 2005: pp. 45-554
目的报告我们在达喀尔颅内脑膜瘤手术的经验。方法作者报告了24例在达喀尔母机构不同神经外科单位手术的颅内脑膜瘤患者的回顾性系列。招聘时间为2001年1月至2004年7月。诊断评估主要基于脑ct和解剖病理学。结果包括17名女性和7名男性。我们的患者年龄在21 - 77岁之间,频率峰值在55岁。颅内高血压综合征和社区炎是最常见的诊断情况,发生率为37%。脑断层扫描(ct)使我们有可能提出一个预先诊断的性质。在形貌方面,50%(20%)随访的基底脑膜瘤为凸性脑膜瘤。辛普森a级对手术质量的评价为20%为I级,64%为II级。12%的术后死亡率是由于缺乏技术基础和缺乏神经麻醉技能造成的。这项工作使我们能够提出一种改善撒哈拉以南非洲肿瘤神经外科实践的策略。目的报告达喀尔颅内脑膜瘤手术的经验。方法我们分析了24名在不同于我们母亲机构的神经外科病房接受手术的患者。对所有患者进行了脑CT扫描,并对所有患者进行了组织病理学确认。在性别方面,我们有17名女性和7名男性。患者年龄21 - 77岁,平均年龄55岁。= =地理= =根据美国人口普查,该县的总面积为,其中土地和(1.6%)水。is Our诊断评估基于CT扫描尽头的50%,convexity meningiomas and one .By 20%体重分级评估to the quality of手术设备使用辛普森resection失物招领,we 64% of职系II and only 20% of I.A 12% of postoperative mort脾测验结果通知related is on the medical and the lack of neuroanesthesists。结论我们概述了一项改善撒哈拉以南国家神经外科实践的计划。关键词:非洲,脑膜瘤,神经外科,塞内加尔,肿瘤,非洲,脑膜瘤,神经外科,塞内加尔非洲神经科学杂志第24卷(1)2005:45-554页
{"title":"Chirurgie Des Méningiomes Intracrâniens Dans Une Unité Neurochirurgicale De Dakar","authors":"Y. Sakho, F. Holden, N. Ndoye, M. Ba, Diene, S. Badiane, J. Dangou, F. Diouf, K. Dia, C. Seck","doi":"10.4314/AJNS.V24I1.7562","DOIUrl":"https://doi.org/10.4314/AJNS.V24I1.7562","url":null,"abstract":"Objectifs \u0000Rapporter notre experience sur la chirurgie des meningiomes intracrâniens a Dakar .\u0000\u0000Methode \u0000Les auteurs rapportent une serie retrospective de 24 patients porteurs de meningiomes intracrâniens operes dans une unite neurochirurgicale differente de notre institution mere a Dakar . Le recrutement s'est fait de Janvier 2001 a Juillet 2004. L'evaluation diagnostique a repose essentiellement sur la tomodensitometrie cerebrale et l'anatomo-pathologie.\u0000\u0000Resultats \u0000Il s'agissait de 17 femmes et de 7 hommes. L'âge de nos patients variaient entre 21 et 77 ans avec un pic de frequence a 55 ans . Le syndrome d'hypertension intracrânienne et la comitialite ont ete les circonstances diagnostiques les plus frequentes avec un taux de 37%. La tomodensitometrie cerebrale a permis d'evoquer un diagnostic presomptif de nature. Concernant la topographie, les meningiomes de la convexite ont ete observes dans 50% des cas suivis par les meningiomes de la base (20%). L'evaluation de la qualite de l'exerese chirurgicale selon le grading de Simpson a retrouve 20% de grade I et 64% de grade II. L'insuffisance du plateau technique et le manque de competences en neuroanesthesie rendent compte de la mortalite post-operatoire de 12%.\u0000\u0000Conclusion \u0000Ce travail nous permet de proposer une strategie d'amelioration de la pratique neurochirurgicale tumorale en Afrique subsaharienne.\u0000\u0000 Objective \u0000To report our experience of intracranial meningiomas surgery in Dakar.\u0000\u0000Method We analysed a population of 24 patients who underwent operation in a Neurosurgical unit different from our mother Institution. Brain CT scan has been done for every patient and histopathological confirmation has been reached for all patients.\u0000\u0000Results \u0000Regarding sex, we have 17 females for 7 males. The patient age was between 21 and 77 years old with a mean of 55.Intracranial hypertension and seizures were the main symptoms encountered with 37% for each. Our diagnostic evaluation is based on CT scan which showed 50% of convexity meningiomas and 20% basal one .By using Simpson grading to assess the quality of surgical resection ,we found 64% of grade II and only 20% of grade I.A 12% of postoperative death rate is related on the substandard medical set and the lack of neuroanesthesists.\u0000\u0000Conclusion \u0000We outlined a program to improve the neurosurgery practice in Sub-Saharan countries.\u0000\u0000 Keywords : Afrique, meningiomes intracrâniens, neurochirurgie, Senegal, tumeurs, Africa, intracranial tumors, meningioma, neurosurgery, Senegal African Journal of Neurological Sciences Vol. 24 (1) 2005: pp. 45-554","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"24 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2008-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70466032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ao Molomo, J. Emejulu, A. Odukogbe, W. Shokunbi, Shokunbi Mt
Study design A prospective study of 3 patients with incomplete cervical spinal cord injury in the 3rd trimester of pregnancy. Objectives To determine the effect of spinal cord injury and treatment with Gardner-Wells' Tong traction on pregnancy, labour and parturition; and ascertain the effectiveness and safety of this conservative form of management in pregnancy. Setting The patients were admitted and managed between September 2002 and May 2004, in the University College Hospital Ibadan, Nigeria - the major referral Centre in neurological diseases for about a quarter to a third of Nigeria's population. Methods From the point of admission into our Emergency Unit, data on each patient was documented prospectively until discharge to the out-patient clinic where each of them was followed up at appointed intervals. These data were then analyzed and compared with reports in literature. Results All the patients had good outcome from the conservative management as measured by complete neurological recovery, uneventful pregnancy and normal parturition. They however, seem to be disposed to pre-term labour, without being aware of the labour pains. Conclusion Spinal cord injury in pregnancy could be successfully manage with Gardner-Wells' Tong traction without deleterious effects on pregnancy and parturition, but appears to induce pre-term labour, associated with regional analgesia for labour pains. Etude prospecitve de 3 patientes presentant un traumatisme du rachis cervical au cours du 3eme trimestre de la grossesse. Determiner les effets du traumatisme rachi-medullaire au cours d'un traitement par traction cervicale de Gardner-Well dutant le travail et l'accouchement. Les patientes ont ete admises entre septembre 2002 et mai 2004 au centre hospitalier et universitaire d'Ibadan, Nigeria, centre referent neurochirurgical pour environ le tiers voire la moitie de la population du Nigeria. Les donnees cliniques et paracliniques ont ete recueillies de l'admission jusqu'a la sortie et au cours des consultations de controle puis analysees par rapport aux observations de la litterature. Tous les patients ont eu une evolution favorable avec le traitement conservateur que nous avons adopte, avec une recuperation neurologique complete, une absence d'evenement indesirable lors du travail, de l'accouchent et des suites de couches. Keywords : Cervical spinal cord. Gardner-Wells' Tongs traction. Third trimester gestation African Journal of Neurological Sciences Vol. 25 (2) 2006: pp. 6-12
研究设计:对3例妊娠晚期不完全性颈脊髓损伤患者进行前瞻性研究。目的探讨脊髓损伤及脊髓牵引治疗对妊娠、分娩和分娩的影响;并确定这种保守管理方式在妊娠期的有效性和安全性。这些患者于2002年9月至2004年5月在尼日利亚伊巴丹大学学院医院入院并接受治疗,该医院是尼日利亚约四分之一至三分之一人口的主要神经疾病转诊中心。方法从进入急诊科开始,对每位患者的数据进行前瞻性记录,直到出院到门诊,在指定的时间间隔对每位患者进行随访。然后对这些数据进行分析,并与文献报道进行比较。结果所有患者经保守治疗后神经功能完全恢复,妊娠顺利,分娩正常。然而,他们似乎倾向于早产,而没有意识到分娩的痛苦。结论采用Gardner-Wells ' s Tong牵引可成功治疗妊娠期脊髓损伤,对妊娠和分娩无不良影响,但可能诱发早产,并伴有产痛局部镇痛。对3例颈椎非外伤性损伤患者进行前瞻性研究。确定创伤性脊柱髓质损伤的影响,并对创伤性脊柱髓质损伤的过程进行分析。2002年9月至2004年5月,尼日利亚伊巴丹大学医院中心,尼日利亚人口动力中心,神经外科参考中心。临床诊断和辅助诊断不包括临床诊断和临床诊断,也不包括临床诊断和临床诊断,也不包括临床诊断和临床诊断。两组患者均可选择一组进化有利的治疗方案,一组治疗方案采用保守治疗方案,一组治疗方案神经系统完整,一组治疗方案不完善,一组治疗方案不完善,一组治疗方案不完善。关键词:颈脊髓;Gardner-Wells ' tong的牵引力。非洲神经科学杂志Vol. 25 (2) 2006: pp. 6-12
{"title":"Cervical spine cord injury in pregnancy. Conservative management of 3 consecutive cases in Ibadan, Nigeria","authors":"Ao Molomo, J. Emejulu, A. Odukogbe, W. Shokunbi, Shokunbi Mt","doi":"10.4314/ajns.v25i2.7582","DOIUrl":"https://doi.org/10.4314/ajns.v25i2.7582","url":null,"abstract":"Study design A prospective study of 3 patients with incomplete cervical spinal cord injury in the 3rd trimester of pregnancy. Objectives To determine the effect of spinal cord injury and treatment with Gardner-Wells' Tong traction on pregnancy, labour and parturition; and ascertain the effectiveness and safety of this conservative form of management in pregnancy. Setting The patients were admitted and managed between September 2002 and May 2004, in the University College Hospital Ibadan, Nigeria - the major referral Centre in neurological diseases for about a quarter to a third of Nigeria's population. Methods From the point of admission into our Emergency Unit, data on each patient was documented prospectively until discharge to the out-patient clinic where each of them was followed up at appointed intervals. These data were then analyzed and compared with reports in literature. Results All the patients had good outcome from the conservative management as measured by complete neurological recovery, uneventful pregnancy and normal parturition. They however, seem to be disposed to pre-term labour, without being aware of the labour pains. Conclusion Spinal cord injury in pregnancy could be successfully manage with Gardner-Wells' Tong traction without deleterious effects on pregnancy and parturition, but appears to induce pre-term labour, associated with regional analgesia for labour pains. Etude prospecitve de 3 patientes presentant un traumatisme du rachis cervical au cours du 3eme trimestre de la grossesse. Determiner les effets du traumatisme rachi-medullaire au cours d'un traitement par traction cervicale de Gardner-Well dutant le travail et l'accouchement. Les patientes ont ete admises entre septembre 2002 et mai 2004 au centre hospitalier et universitaire d'Ibadan, Nigeria, centre referent neurochirurgical pour environ le tiers voire la moitie de la population du Nigeria. Les donnees cliniques et paracliniques ont ete recueillies de l'admission jusqu'a la sortie et au cours des consultations de controle puis analysees par rapport aux observations de la litterature. Tous les patients ont eu une evolution favorable avec le traitement conservateur que nous avons adopte, avec une recuperation neurologique complete, une absence d'evenement indesirable lors du travail, de l'accouchent et des suites de couches. Keywords : Cervical spinal cord. Gardner-Wells' Tongs traction. Third trimester gestation African Journal of Neurological Sciences Vol. 25 (2) 2006: pp. 6-12","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"25 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Contexte La cryptococcose est une affection fungique frequente chez les personnes immunodeprimees pour laquelle peu d'etudes ont ete menees au Cameroun. But Decrire les aspects epidemiologiques, cliniques, biologiques et evolutifs de la cryptococcose neuro-meningee. Materiel et methodes Etude retrospective et descriptive menee a partir des dossiers medicaux des patients hospitalises pendant 57 mois dans le service de medecine interne du Centre Hospitalier et Universitaire de Yaounde (CHUY). Resultats Trente et trois cas de meningite cryptococcique ont ete diagnostiques sur les 3655 patients hospitalises. Le sexe masculin etait predominant (21 homme/12 femmes). L'âge moyen des patients etait de 39,81 ans. Les manifestations cliniques etaient : les cephalees (26 cas /33), la fievre (25 cas /33), les signes meninges (18 cas /33), les troubles de la conscience (9 cas/33) et les crises epileptiques generalisees (8 cas /33). L'infection par Mycobacterium tuberculosis etait la pathologie associee (10 fois/33) la plus frequente. La duree moyenne de l'evolution des symptomes avant le diagnostic etait de 14,93 jours. La serologie VIH etait positive chez 32 patients sur 33. La moyenne des lymphocytes CD4 etait de 29,94/mm3 et la mediane a 8 CD4 / mm3. Quatorze patients sur les 33 (42,2%) sont decedes dans un delai de 1 a 21 jours. Cette lourde mortalite est correlee au retard de mise en route d'un traitement adequat, a la coexistence d'une infection a Mycobacterium tuberculosis et a la mauvaise observance du traitement. Conclusion Chez tout patient presume infecte par le VIH, presentant un syndrome meninge franc ou fruste avec des cephalees, des troubles de la vigilance et des crises epileptiques, la realisation systematique d'une ponction lombaire et la recherche des cryptocoques dans le LCR sont recommandees afin de mettre en route rapidement un traitement adequat, afin de diminuer la mortalite qui reste elevee Background Cryptococcus neoformans is an important fungal pathogen in immunocompromised patients. Cryptococcal meningitis has not been well studied in Cameroon. Aim To describe the epidemiological, clinical, biological aspects and course of cryptococcal meningitis in patients admitted in the Yaounde University Teaching Hospital. Materials and methods: Retrospective and descriptive study conducted over a 57-month period in the Yaounde University Teaching Hospital. Results During this period, cryptococcal meningitis was diagnosed in 33 patients among the 3,655 patients who were hospitalised in the Internal Medicine service. There was a male predominance (21 males/ 12 females) in our study. The mean age of the patients was 39.81 years. The clinical features were variable: Headaches (26 cases /33), fever (25/33), signs of meningitis (18/33), altered consciousness (9/33) and generalised epileptic seizures (8/33). Mycobacterium tuberculosis infection was the most associated with cryptococcal meningitis (10 cases /33). The mean period of ev
{"title":"La Cryptococcose Neuro-Meningee Et L'infection Au Vih Dans Le Service De Medecine Du Centre Hospitalier Et Universitaire De Yaounde, Cameroun","authors":"J. Mbuagbaw, Biholong, A. Njamnshi","doi":"10.4314/AJNS.V25I2.7583","DOIUrl":"https://doi.org/10.4314/AJNS.V25I2.7583","url":null,"abstract":"Contexte La cryptococcose est une affection fungique frequente chez les personnes immunodeprimees pour laquelle peu d'etudes ont ete menees au Cameroun. But Decrire les aspects epidemiologiques, cliniques, biologiques et evolutifs de la cryptococcose neuro-meningee. Materiel et methodes Etude retrospective et descriptive menee a partir des dossiers medicaux des patients hospitalises pendant 57 mois dans le service de medecine interne du Centre Hospitalier et Universitaire de Yaounde (CHUY). Resultats Trente et trois cas de meningite cryptococcique ont ete diagnostiques sur les 3655 patients hospitalises. Le sexe masculin etait predominant (21 homme/12 femmes). L'âge moyen des patients etait de 39,81 ans. Les manifestations cliniques etaient : les cephalees (26 cas /33), la fievre (25 cas /33), les signes meninges (18 cas /33), les troubles de la conscience (9 cas/33) et les crises epileptiques generalisees (8 cas /33). L'infection par Mycobacterium tuberculosis etait la pathologie associee (10 fois/33) la plus frequente. La duree moyenne de l'evolution des symptomes avant le diagnostic etait de 14,93 jours. La serologie VIH etait positive chez 32 patients sur 33. La moyenne des lymphocytes CD4 etait de 29,94/mm3 et la mediane a 8 CD4 / mm3. Quatorze patients sur les 33 (42,2%) sont decedes dans un delai de 1 a 21 jours. Cette lourde mortalite est correlee au retard de mise en route d'un traitement adequat, a la coexistence d'une infection a Mycobacterium tuberculosis et a la mauvaise observance du traitement. Conclusion Chez tout patient presume infecte par le VIH, presentant un syndrome meninge franc ou fruste avec des cephalees, des troubles de la vigilance et des crises epileptiques, la realisation systematique d'une ponction lombaire et la recherche des cryptocoques dans le LCR sont recommandees afin de mettre en route rapidement un traitement adequat, afin de diminuer la mortalite qui reste elevee Background Cryptococcus neoformans is an important fungal pathogen in immunocompromised patients. Cryptococcal meningitis has not been well studied in Cameroon. Aim To describe the epidemiological, clinical, biological aspects and course of cryptococcal meningitis in patients admitted in the Yaounde University Teaching Hospital. Materials and methods: Retrospective and descriptive study conducted over a 57-month period in the Yaounde University Teaching Hospital. Results During this period, cryptococcal meningitis was diagnosed in 33 patients among the 3,655 patients who were hospitalised in the Internal Medicine service. There was a male predominance (21 males/ 12 females) in our study. The mean age of the patients was 39.81 years. The clinical features were variable: Headaches (26 cases /33), fever (25/33), signs of meningitis (18/33), altered consciousness (9/33) and generalised epileptic seizures (8/33). Mycobacterium tuberculosis infection was the most associated with cryptococcal meningitis (10 cases /33). The mean period of ev","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"25 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Cerebral palsy is a major cause of childhood disability and has been described as one of the three most common life-long developmental disabilities in childhood. It is more prevalent in the more socio-economically deprived populations of the world. Epilepsy is said to occur in 15-90% of children with cerebral palsy and this poses additional economic and psychological stress on affected children and their families. Objectives To describe the risk factors for epilepsy in children with cerebral palsy. Methods One hundred and seventy six children with cerebral palsy seen at the Paediatric Neurology clinic, University College Hospital, Ibadan, Nigeria over a period of two years were studied. The group with epilepsy was compared with that without epilepsy. Appropriate statistical tests were carried out using the SPSS 12 for windows software to identify significant predictors of epilepsy. Results Sixty five of the children studied had associated epilepsy, giving a prevalence rate of 36.9%. The significant predictors of epilepsy after adjusting for other variables were seizures in the first year of life and spastic hemiplegia. Neonatal seizures, home delivery and post infectious brain damage which were significantly independently associated with epilepsy were not significant following logistic regression analysis. Conclusion Epilepsy is a frequent problem in children with cerebral palsy. A history of neonatal seizures, occurrence of seizures in the first year of life, presence of spastic hemiplegia and post infectious brain damage all warrant a close evaluation and appropriate follow up for early detection of epilepsy in children with cerebral palsy. Introduction La paralysie cerebrale est une des causes majeures de handicaps chez l'enfant. Dans le monde entier, elle interesse surtout les couches socio- economiques defavorisees. L'epilepsie peut survenir chez 90 % des enfants presentant une paralysie cerebrale, entrainant ainsi des contraintes economiques et psychologiques chez des familles deja fort depourvues et eprouvees. L'objectif est de decrire les facteurs de risque de l'epilepsie chez les enfants atteints de paralysie cerebrale. Methode 176 enfants avec une paralysie cerebrale ont ete observes a la clinique neurologique pediatrique du centre hospitalier universitaire d'Ibadan, au Nigeria, sur une periode de 2 ans. Le groupe avec epilepsie a ete compare avec ceux qui n'etaient pas atteints par cette affection. Des tests statistiques appropries utilisant le SPSS 12 et un logiciel Windows a permis d'identifier les facteurs predictifs de l'epilepsie. Resultat 65 des patients etudies, avaient une epilepsie impliquant ainsi un taux de prevalence de 36.9 %. Les facteurs predictifs significatifs d'epilepsie apres ajustement des zones variables etaient : les crises lors de la premiere annee de la vie et l'hemiplegie spastique. Les crises neo-natales, l'accouchement a domicile et les sequelles cerebrales post infectieuses etaient
脑瘫是儿童残疾的主要原因,被认为是儿童时期三种最常见的终身发育障碍之一。它在世界上社会经济条件较差的人口中更为普遍。据说15-90%的脑瘫儿童患有癫痫,这给受影响的儿童及其家庭带来了额外的经济和心理压力。目的探讨脑瘫患儿癫痫的危险因素。方法对尼日利亚伊巴丹大学学院医院儿科神经内科就诊的176例脑瘫患儿进行为期两年的研究。将癫痫组与非癫痫组进行比较。采用spss12软件进行相应的统计检验,以确定癫痫的显著预测因素。结果65例患儿合并癫痫,患病率为36.9%。在调整其他变量后,癫痫的显著预测因子是生命第一年的癫痫发作和痉挛性偏瘫。经logistic回归分析,与癫痫有显著独立相关性的新生儿癫痫发作、分娩和感染后脑损伤无显著性差异。结论癫痫是脑瘫患儿的常见病。新生儿癫痫发作史、出生第一年癫痫发作的发生、痉挛性偏瘫和感染性脑损伤的存在都需要对脑瘫儿童癫痫的早期发现进行密切评估和适当的随访。小儿脑麻痹症是一种可造成严重残疾的疾病。当世界变得更完整时,我们的利益超越了我们的社会经济利益。90%的儿童表现为脑瘫、经济和心理障碍、家庭障碍、精神障碍和精神障碍。客观地描述了癫痫的危险因素和小儿麻痹的注意力。方法对176例小儿麻痹性脑瘫患儿在尼日利亚伊巴丹大学附属医院的临床神经儿科进行观察,随访2个月,并对两组癫痫患儿进行比较。Des测试统计数据是否合适,使用SPSS 12和逻辑Windows,并允许使用“标识符”、“因素”和“癫痫病”预测。结果本组65例患者中,未发生1例癫痫性静脉注射,发生率为36.9%。Les因素可显著预测癫痫发作后的调整,区域变量可显著预测癫痫发作后的调整:Les危机可显著预测癫痫发作后的调整和偏瘫性痉挛的调整。新生儿危重症、住院症和继发性脑感染后症状的显著性与癫痫的相关性无关。结论癫痫病在小儿麻痹性脑瘫中是常见的并发症。一种危象的临床史,一种新生儿的显像,一种生命的开端,一种偏瘫痉挛的存在,一种感染后大脑损伤的存在,一种检测癫痫的早熟,一种婴儿的注意力,一种麻痹的大脑。关键词:非洲,癫痫,危险因素,脑瘫非洲神经科学杂志Vol. 25 (2) 2006: pp. 29-37
{"title":"Risk Factors For Epilepsy In Children With Cerebral Palsy","authors":"I. Lagunju, B. Adedokun, Fatunde Oj","doi":"10.4314/AJNS.V25I2.7585","DOIUrl":"https://doi.org/10.4314/AJNS.V25I2.7585","url":null,"abstract":"Background Cerebral palsy is a major cause of childhood disability and has been described as one of the three most common life-long developmental disabilities in childhood. It is more prevalent in the more socio-economically deprived populations of the world. Epilepsy is said to occur in 15-90% of children with cerebral palsy and this poses additional economic and psychological stress on affected children and their families. Objectives To describe the risk factors for epilepsy in children with cerebral palsy. Methods One hundred and seventy six children with cerebral palsy seen at the Paediatric Neurology clinic, University College Hospital, Ibadan, Nigeria over a period of two years were studied. The group with epilepsy was compared with that without epilepsy. Appropriate statistical tests were carried out using the SPSS 12 for windows software to identify significant predictors of epilepsy. Results Sixty five of the children studied had associated epilepsy, giving a prevalence rate of 36.9%. The significant predictors of epilepsy after adjusting for other variables were seizures in the first year of life and spastic hemiplegia. Neonatal seizures, home delivery and post infectious brain damage which were significantly independently associated with epilepsy were not significant following logistic regression analysis. Conclusion Epilepsy is a frequent problem in children with cerebral palsy. A history of neonatal seizures, occurrence of seizures in the first year of life, presence of spastic hemiplegia and post infectious brain damage all warrant a close evaluation and appropriate follow up for early detection of epilepsy in children with cerebral palsy. Introduction La paralysie cerebrale est une des causes majeures de handicaps chez l'enfant. Dans le monde entier, elle interesse surtout les couches socio- economiques defavorisees. L'epilepsie peut survenir chez 90 % des enfants presentant une paralysie cerebrale, entrainant ainsi des contraintes economiques et psychologiques chez des familles deja fort depourvues et eprouvees. L'objectif est de decrire les facteurs de risque de l'epilepsie chez les enfants atteints de paralysie cerebrale. Methode 176 enfants avec une paralysie cerebrale ont ete observes a la clinique neurologique pediatrique du centre hospitalier universitaire d'Ibadan, au Nigeria, sur une periode de 2 ans. Le groupe avec epilepsie a ete compare avec ceux qui n'etaient pas atteints par cette affection. Des tests statistiques appropries utilisant le SPSS 12 et un logiciel Windows a permis d'identifier les facteurs predictifs de l'epilepsie. Resultat 65 des patients etudies, avaient une epilepsie impliquant ainsi un taux de prevalence de 36.9 %. Les facteurs predictifs significatifs d'epilepsie apres ajustement des zones variables etaient : les crises lors de la premiere annee de la vie et l'hemiplegie spastique. Les crises neo-natales, l'accouchement a domicile et les sequelles cerebrales post infectieuses etaient","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"25 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Myasthenia gravis (MG) together with Lambert-Eaton myasthenic syndrome (LEMS) in the same patient is rarely described. This is a case report of a patient who initially presented with myasthenia gravis and later complicated with presumably auto-immune LEMS. The patient was noted to be HIV positive. The interest lies in the behaviour of MG in immunocompromised patients and the electrophysiological changes at the neuromuscular junction in patients with both MG and LEMS. We present a patient who is HIV positive with a long history of MG and a possibly a more recent diagnosis of LEMS. RESUME L'association myasthenie et syndrome de Lambert-Eaton chez un patient est rarement decrit. Nous rapportons le cas d'un patient, VIH positif, s'etant presente initialement par une myasthenie, completee ulterieurement par un syndrome de Lambert Eaton vraisemblablement d'origine auto-immune et discutons les liens eventuels, au plan pathogenique. Key words : Myasthenia Gravis, Lambert Eaton myasthenic syndrome, HIV, Myasthenie, syndrome de Lambert-Eaton, virus d'immunodeficience acquise, VIH African Journal of Neurological Sciences Vol.23(2) 2004
{"title":"POSSIBLE MYASTHENIA AND LEMS IN THE SAME PATIENT :CASE REPORT AND REVIEW OF THE LITERATURE","authors":"V. Patel, P. Bill, A. Bhigjee","doi":"10.4314/AJNS.V23I2.7557","DOIUrl":"https://doi.org/10.4314/AJNS.V23I2.7557","url":null,"abstract":"ABSTRACT \u0000Myasthenia gravis (MG) together with Lambert-Eaton myasthenic syndrome (LEMS) in the same patient is rarely described. This is a case report of a patient who initially presented with myasthenia gravis and later complicated with presumably auto-immune LEMS. The patient was noted to be HIV positive. The interest lies in the behaviour of MG in immunocompromised patients and the electrophysiological changes at the neuromuscular junction in patients with both MG and LEMS. We present a patient who is HIV positive with a long history of MG and a possibly a more recent diagnosis of LEMS. RESUME \u0000L'association myasthenie et syndrome de Lambert-Eaton chez un patient est rarement decrit. Nous rapportons le cas d'un patient, VIH positif, s'etant presente initialement par une myasthenie, completee ulterieurement par un syndrome de Lambert Eaton vraisemblablement d'origine auto-immune et discutons les liens eventuels, au plan pathogenique. Key words : Myasthenia Gravis, Lambert Eaton myasthenic syndrome, HIV, Myasthenie, syndrome de Lambert-Eaton, virus d'immunodeficience acquise, VIH African Journal of Neurological Sciences Vol.23(2) 2004","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2005-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Cissé, Y. Morel, A. Cissé, N. Câmara, B. Cisse, M. Doukoure, I. Souare, M. Barry, S. Camara, S. Kourouma, M. Diaby, L. Dasilva, A. Sylla, H. Dia
PARALYSIE GENERALE EN MILIEU TROPICAL. ETUDE DE 43 OBSERVATIONS RESUME Description :Les auteurs rapportent une etude de 43 cas de paralysie generale, reveles par un syndrome dementiel et des formes atypiques notamment les troubles confusionnels repetitifs et des crises epileptiformes. Objectif : L'objectif de cette etude est de reevaluer cette pathologie du point de vue clinique et paraclinique en milieu tropical. Methode : Il s'agit d'une etude prospective. Le diagnostic a repose sur la positivite des reactions serologiques ( VDRL-TPHA) dans le sang et le liquide cephalo-rachidien, la presence d'une hypercellularite a predominance lymphocytaire et d'une hyperproteinorachie. Resultats : Les troubles cognitifs et moteurs, les etats confusionnels repetitifs et les crises epileptiques constituent les formes cliniques dominantes de debut. Chez tous les patients, le scanner a mis en evidence une discrete dilatation ventriculaire diffuse et un elargissement des sillons de la convexite. Le trace electroencephalographique etait anormal dans pres de 67% des cas. SUMMARY Description : The authors report a study of 43 cases of general paralysis revealed by some mental disorders and atypical forms notably repeater confessional disorders and some seizure-like attacks. Objective : The goal of this study is to revalue this pathology from the clinical and paraclinic point of view in tropical medium. Method : In this prospective study, the diagnosis was based on the serologic tests (VDRL-TPHA) in the blood and the cerebrospinal fluid (CSF); CSF cell count with lymphocyte predominance ; protein level in the fluid. Result : The diagnosis was based on the serologic tests (VDRL-TPHA) in the blood and the cerebrospinal fluid(CSF); high CSF cell count with lymphocyte predominance; high protein level in the fluid. The cogniture and motor troubles, the repeated confusion status and the epileptic seizures constitute the dominant clinical forms of the onset. In all the patients, the CT-scan revealed discrete diffuse ventricular dilation and widening of the grooves of the convexity. The electroencephalographic traces were abnormal in 67% of the cases. Key Words: Afrique, Guinee, paralysie generale, syphilis nerveuse, Africa, Guinea, general paralysis, neurosyphilis African Journal of Neurological Sciences Vol.23(2) 2004
热带地区的全身性瘫痪。描述:作者报告了一项对43例全身性瘫痪的研究,表现为痴呆综合征和非典型形式,包括重复性混杂障碍和癫痫样癫痫发作。目的:本研究的目的是在热带环境中从临床和临床旁的角度重新评估这种病理。方法:本研究为前瞻性研究。a的诊断是基于血液和脑脊液中的血清学反应阳性(VDRL-TPHA),存在以淋巴细胞为主的高细胞炎和高蛋白缺血。结果:认知和运动障碍、重复混乱状态和癫痫发作是发病的主要临床形式。在所有患者中,扫描显示弥漫性心室扩张和凸面沟扩大。近67%的病例脑电图异常。摘要描述:作者报告了一项关于43例全身性瘫痪的研究,揭示了一些精神障碍和非典型形式的明显重复的自白障碍和一些类似癫痫的攻击。客观:The goal of this study is to revalue this pathology from The clinical and paraclinic point of view in tropical medium。方法:在本前瞻性研究中,诊断依据血液和脑脊液血清学试验(VDRL-TPHA);以淋巴细胞为主的脑脊液细胞计数;= =地理= =根据美国人口普查局的数据,该县总面积为,其中土地和(1.5%)水。结果:诊断依据血液和脑脊液血清学检测(VDRL-TPHA);脑脊液细胞计数高,淋巴细胞占优势;= =地理= =根据美国人口普查局的数据,该县总面积为,其中土地和(1.5%)水。认知和运动障碍、重复混乱状态和癫痫发作是发病的主要临床形式。在所有患者中,ct扫描显示离散弥漫性心室扩张和凹凸沟槽扩大。在67%的病例中,脑电图显示异常。关键词:非洲,几内亚,全瘫,神经梅毒,非洲,几内亚,全瘫,神经梅毒非洲神经科学杂志第23卷(2)2004
{"title":"GENERAL PARALYSIS IN A TROPICAL COUNTRY. STUDY OF 43 OBSERVATIONS","authors":"A. Cissé, Y. Morel, A. Cissé, N. Câmara, B. Cisse, M. Doukoure, I. Souare, M. Barry, S. Camara, S. Kourouma, M. Diaby, L. Dasilva, A. Sylla, H. Dia","doi":"10.4314/AJNS.V23I2.7556","DOIUrl":"https://doi.org/10.4314/AJNS.V23I2.7556","url":null,"abstract":"PARALYSIE GENERALE EN MILIEU TROPICAL. ETUDE DE 43 OBSERVATIONS \u0000RESUME \u0000Description :Les auteurs rapportent une etude de 43 cas de paralysie generale, reveles par un syndrome dementiel et des formes atypiques notamment les troubles confusionnels repetitifs et des crises epileptiformes. \u0000Objectif : L'objectif de cette etude est de reevaluer cette pathologie du point de vue clinique et paraclinique en milieu tropical. \u0000Methode : Il s'agit d'une etude prospective. Le diagnostic a repose sur la positivite des reactions serologiques ( VDRL-TPHA) dans le sang et le liquide cephalo-rachidien, la presence d'une hypercellularite a predominance lymphocytaire et d'une hyperproteinorachie. \u0000Resultats : Les troubles cognitifs et moteurs, les etats confusionnels repetitifs et les crises epileptiques constituent les formes cliniques dominantes de debut. Chez tous les patients, le scanner a mis en evidence une discrete dilatation ventriculaire diffuse et un elargissement des sillons de la convexite. Le trace electroencephalographique etait anormal dans pres de 67% des cas. SUMMARY \u0000Description : The authors report a study of 43 cases of general paralysis revealed by some mental disorders and atypical forms notably repeater confessional disorders and some seizure-like attacks. \u0000Objective : The goal of this study is to revalue this pathology from the clinical and paraclinic point of view in tropical medium. \u0000Method : In this prospective study, the diagnosis was based on the serologic tests (VDRL-TPHA) in the blood and the cerebrospinal fluid (CSF); CSF cell count with lymphocyte predominance ; protein level in the fluid. \u0000Result : The diagnosis was based on the serologic tests (VDRL-TPHA) in the blood and the cerebrospinal fluid(CSF); high CSF cell count with lymphocyte predominance; high protein level in the fluid. The cogniture and motor troubles, the repeated confusion status and the epileptic seizures constitute the dominant clinical forms of the onset. In all the patients, the CT-scan revealed discrete diffuse ventricular dilation and widening of the grooves of the convexity. The electroencephalographic traces were abnormal in 67% of the cases. Key Words: Afrique, Guinee, paralysie generale, syphilis nerveuse, Africa, Guinea, general paralysis, neurosyphilis African Journal of Neurological Sciences Vol.23(2) 2004","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"39 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2005-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizabeth Urowayino Onifade, F. E. A. Lesi, V. C. Ezeaka, Adenike Olufunmilayo Grange
NEUROLOGICAL SEQUELAE IN CHILDREN WITH PYOGENIC MENINGITIS IN A TERTIARY CENTRE IN LAGOS (NIGERIA ABSTRACT Background: Neurological sequelae following childhood bacterial meningitis are common particularly in the presence of delayed diagnosis and treatment. The latter is commonplace with meningitis in developing countries like Nigeria but information on the incidence and prevalence rates of consequent neurological sequelae is rare. Objective: We herein document the prevalence of such sequelae in children following admission for pyogenic meningitis and describe associated risk factors. Methods: We retrospectively reviewed forty-nine children managed for acute pyogenic meningitis at the Lagos University Teaching Hospital (LUTH) over a 10-year period. Information on biodata, clinical features, pre–admission treatment, investigation results, treatment, and duration of hospitalization were extracted from their case records and analysed. Results: Thirty-two (65.3%) of these children had obvious neurological sequelae. These included neuro-motor disorders (31%), hydrocephalus (28%), hearing disorders (25%), speech and language problems (25%), recurrent seizures (22%), mental retardation (22%), visual defects (19%) and behavioural problems (3%). All ages were affected but more commonly infants. Sequelae occurred in multiples. Children with sequelae tended to have had prior hospitalization and treatment. However no clinical or socio-economic factors showed significant relationship with the development of neurological sequelae. Conclusions: The distribution of sequelae in our study is similar to findings of other authors but shows a higher prevalence thus further confirming the need for primary prevention of this disease and for prompt and adequate treatment of cases. We recommend early screening of survivors for sequelae so that adequate rehabilitation can be planned. RESUME Introduction: Les sequelles neurologiques secondaire a une meningite bacterienne au cours de l'enfance sont frequentes en particulier lorsque le diagnostic et le traitement sont retardes. Objectif: Nous rapportons dans ce travail les aspects sequellaires neurologiques observes chez les enfants hospitalises pour meningite pyogenique en relevant les facteurs de risque lies a cette affection. Methode: Nous avons passe en revue retrospectivement, quarante neuf enfants traites atteints de la meningite purulante au centre hospitalier universitaire de Lagos (LUTH) au cours d'une periode de 10 ans. Les informations cliniques, paracliniques et therapeutiques tires de leurs dossiers medicaux ont ete analyses. Resultats: Trente deux soit 65,3% des cas enfants presentaient des sequelle neurologicales: troubles neuro-moteurs (31%), hydrocephalie (28%), troubles de l'ouie (25%), troubles du language et (25%), crise chronique (22%), retard mentale (22%), troubles visuelles (19%) et de comportement (3%). Aucun facteur clinique, socio-economique n'a pas ete releve et relie avec la survenue d
{"title":"SEQUELLES NEUROLOGIQUES CHEZ DES ENFANTS ATTEINTS D'UNE MENINGITE PURULENTE DANS UN CENTRE TERTIAIRE A LAGOS (NIGERIA)","authors":"Elizabeth Urowayino Onifade, F. E. A. Lesi, V. C. Ezeaka, Adenike Olufunmilayo Grange","doi":"10.4314/AJNS.V23I2.7555","DOIUrl":"https://doi.org/10.4314/AJNS.V23I2.7555","url":null,"abstract":"NEUROLOGICAL SEQUELAE IN CHILDREN WITH PYOGENIC MENINGITIS IN A TERTIARY CENTRE IN LAGOS (NIGERIA \u0000ABSTRACT \u0000Background: Neurological sequelae following childhood bacterial meningitis are common particularly in the presence of delayed diagnosis and treatment. The latter is commonplace with meningitis in developing countries like Nigeria but information on the incidence and prevalence rates of consequent neurological sequelae is rare. \u0000Objective: We herein document the prevalence of such sequelae in children following admission for pyogenic meningitis and describe associated risk factors. \u0000Methods: We retrospectively reviewed forty-nine children managed for acute pyogenic meningitis at the Lagos University Teaching Hospital (LUTH) over a 10-year period. Information on biodata, clinical features, pre–admission treatment, investigation results, treatment, and duration of hospitalization were extracted from their case records and analysed. \u0000Results: Thirty-two (65.3%) of these children had obvious neurological sequelae. These included neuro-motor disorders (31%), hydrocephalus (28%), hearing disorders (25%), speech and language problems (25%), recurrent seizures (22%), mental retardation (22%), visual defects (19%) and behavioural problems (3%). All ages were affected but more commonly infants. Sequelae occurred in multiples. \u0000Children with sequelae tended to have had prior hospitalization and treatment. However no clinical or socio-economic factors showed significant relationship with the development of neurological sequelae. \u0000Conclusions: The distribution of sequelae in our study is similar to findings of other authors but shows a higher prevalence thus further confirming the need for primary prevention of this disease and for prompt and adequate treatment of cases. We recommend early screening of survivors for sequelae so that adequate rehabilitation can be planned. RESUME \u0000Introduction: Les sequelles neurologiques secondaire a une meningite bacterienne au cours de l'enfance sont frequentes en particulier lorsque le diagnostic et le traitement sont retardes. \u0000Objectif: Nous rapportons dans ce travail les aspects sequellaires neurologiques observes chez les enfants hospitalises pour meningite pyogenique en relevant les facteurs de risque lies a cette affection. \u0000Methode: Nous avons passe en revue retrospectivement, quarante neuf enfants traites atteints de la meningite purulante au centre hospitalier universitaire de Lagos (LUTH) au cours d'une periode de 10 ans. Les informations cliniques, paracliniques et therapeutiques tires de leurs dossiers medicaux ont ete analyses. \u0000Resultats: Trente deux soit 65,3% des cas enfants presentaient des sequelle neurologicales: troubles neuro-moteurs (31%), hydrocephalie (28%), troubles de l'ouie (25%), troubles du language et (25%), crise chronique (22%), retard mentale (22%), troubles visuelles (19%) et de comportement (3%). Aucun facteur clinique, socio-economique n'a pas ete releve et relie avec la survenue d","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2005-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GELINEAU SYNDROME: LITERATURE REVIEW AND MANAGEMENT OF A NIGERIAN TEENAGER SUMMARY Gelineau syndrome is a rare disorder with a hospital prevalence of 0.026% in Nigeria. A 14-year old Nigerian with narcolepsy, cataplexy, visual hypnagogic hallucinations and hypnapompic sleep paralysis is presented here. He had a Multiple Sleep Latency Test done using the Carscadon protocol. With the exclusion of other differential diagnoses, this patient satisfied the DSM IV, Carscadon's Multiple Sleep Latency Test and the Silber Category A criteria for definite narcolepsy. He was controlled on methylphenidate and programmed daily naps. RESUME Au Nigeria, le syndrome de Gelineau est un trouble rare avec une prevalence hospitaliere de 0.026%. Nous etudions ici le cas d'un patient nigerien âge de 14 ans atteint de narcolepsie, de cataplexie, d'hallucinations hypnagogiques visuelles et de paralysie du sommeil hypnopompique. Il a ete effectue un test de latence multiples d'endormissement en utilisant le protocole de Carscadon. En excluant d'autres diagnostics differentiels, ce patient repond au DSM IV, le test de latence multiple d'endormissement de Carscadon et du Silber Categori un critere determinant la narcolepsie. Le patient a ete mis sous methylphenidate et des siestes quotidiennes lui furent preconisees. Key Words: Cataplexy, Narcolepsy, Nigeria, Afrique, Cataplexie, narcolepsie, Nigeria African Journal of Neurological Sciences Vol.23(2) 2004
摘要GELINEAU综合征是一种罕见的疾病,在尼日利亚的医院患病率为0.026%。一个14岁的尼日利亚人,患有嗜睡症,猝倒,视觉睡眠幻觉和睡眠麻痹。他用Carscadon协议做了多次睡眠潜伏期测试。排除其他鉴别诊断,该患者满足DSM IV, Carscadon's多重睡眠潜伏期试验和Silber A类标准确定嗜睡症。他被控制服用哌甲酯,并安排每天小睡。在尼日利亚,格里内诺综合征非常罕见,在一家医院的患病率仅为0.026%。目前的研究包括:嗜睡症、猝倒症、幻觉、幻觉和催眠麻痹症。在使用Carscadon协议的情况下,将有效地测试延迟倍数。在排除诊断差异的情况下,患者对DSM IV的反应,以及对Carscadon和du Silber分类非标准决定性嗜睡症的潜伏期的多重测试。1例患者使用盐酸哌甲酯治疗,并在急性发作前治疗。关键词:猝倒,发作性睡病,尼日利亚,非洲,猝倒,发作性睡病,尼日利亚,非洲神经科学Vol.23(2) 2004
{"title":"SYNDROME DE GELINEAU. A PROPOS D'UN CAS NIGERIAN ET REVUE DE LA LITERATURE","authors":"Mayowa O. Owolabi, Adesola Ogunniyi","doi":"10.4314/AJNS.V23I2.7558","DOIUrl":"https://doi.org/10.4314/AJNS.V23I2.7558","url":null,"abstract":"GELINEAU SYNDROME: LITERATURE REVIEW AND MANAGEMENT OF A NIGERIAN TEENAGER SUMMARY \u0000Gelineau syndrome is a rare disorder with a hospital prevalence of 0.026% in Nigeria. A 14-year old Nigerian with narcolepsy, cataplexy, visual hypnagogic hallucinations and hypnapompic sleep paralysis is presented here. He had a Multiple Sleep Latency Test done using the Carscadon protocol. With the exclusion of other differential diagnoses, this patient satisfied the DSM IV, Carscadon's Multiple Sleep Latency Test and the Silber Category A criteria for definite narcolepsy. He was controlled on methylphenidate and programmed daily naps. RESUME \u0000Au Nigeria, le syndrome de Gelineau est un trouble rare avec une prevalence hospitaliere de 0.026%. Nous etudions ici le cas d'un patient nigerien âge de 14 ans atteint de narcolepsie, de cataplexie, d'hallucinations hypnagogiques visuelles et de paralysie du sommeil hypnopompique. Il a ete effectue un test de latence multiples d'endormissement en utilisant le protocole de Carscadon. En excluant d'autres diagnostics differentiels, ce patient repond au DSM IV, le test de latence multiple d'endormissement de Carscadon et du Silber Categori un critere determinant la narcolepsie. Le patient a ete mis sous methylphenidate et des siestes quotidiennes lui furent preconisees. Key Words: Cataplexy, Narcolepsy, Nigeria, Afrique, Cataplexie, narcolepsie, Nigeria African Journal of Neurological Sciences Vol.23(2) 2004","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2005-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Djientcheu, A. K. Njamnshi, P. Ongolo-Zogo, L. Dongmo, J. Eloundou, B. Rilliet, W. Muna, A. Essomba, M. Sosso
HYDROCEPHALUS: A RARE PRESENTATION OF CENTRAL NERVOUS SYSTEM TOXOPLASMOSIS IN THE ACQUIRED IMMUNODEFICIENCY SYNDROME SUMMARY The incidence of HIV infection and the neurological complications are increasing, especially in developing countries. Hydrocephalus due to cerebral toxoplasmosis is very rare and only 7 cases have been reported in the literature . The authors report a case of hydrocephalus related to toxoplasmosis of the 4th ventricles in a HIV patient successfully treated medically without shunting. The mechanism of the hydrocephalus is a necrotizing ependymitis and plexitis obstructing the CSF flow although the cerebral parenchyma has a normal CT appearance in many cases. CNS toxoplasmosis should be ruled out in any immuno-deficient patient with hydrocephalus of unknown origin. The permanent CSF shunting may not be necessary in hydrocephalus due to CNS toxoplasmosis, and external CSF shunting may only rarely be needed. RESUME Les auteurs presentent un cas d'hydrocephalie associee a une toxoplasmose du IV eme ventricule chez un patient HIV positif, traite medicalement avec succes, sans derivation du LCS. Le mecanisme de l'hydrocephalie est une ependymite et une plexite necrosante obstruant la circulation du LCS, meme si le parenchyme cerebral apparait normal au scanner dans plusieurs cas. Une toxoplasmose du systeme nerveux central doit etre recherchee chez tout patient immunodeprime avec une hydrocephalie d'etiologie indeterminee. Une derivation permanente du LCS ne serait pas necessaire au cours de l'hydrocephalie entrant dans ce cadre. La derivation ventriculaire externe peut etre implantee dans de rares conditions. Key Words: CNS toxoplasmosis, AIDS, hydrocephalus, medical treatment, Cameroon, Afrique, Cameroun, Hydrocephalie, Toxoplasmose, VIH, SIDA African Journal of Neurological Sciences Vol.23(2) 2004
{"title":"HYDROCEPHALIE: UN CAS RARE DE TOXOPLAMOSE CEREBRALE DANS LE CADRE D'UN SYNDROME D'IMMUNO-DEFICIENCE ACQUISE","authors":"V. Djientcheu, A. K. Njamnshi, P. Ongolo-Zogo, L. Dongmo, J. Eloundou, B. Rilliet, W. Muna, A. Essomba, M. Sosso","doi":"10.4314/AJNS.V23I2.7559","DOIUrl":"https://doi.org/10.4314/AJNS.V23I2.7559","url":null,"abstract":"HYDROCEPHALUS: A RARE PRESENTATION OF CENTRAL NERVOUS SYSTEM TOXOPLASMOSIS IN THE ACQUIRED IMMUNODEFICIENCY SYNDROME \u0000SUMMARY \u0000The incidence of HIV infection and the neurological complications are increasing, especially in developing countries. Hydrocephalus due to cerebral toxoplasmosis is very rare and only 7 cases have been reported in the literature . The authors report a case of hydrocephalus related to toxoplasmosis of the 4th ventricles in a HIV patient successfully treated medically without shunting. The mechanism of the hydrocephalus is a necrotizing ependymitis and plexitis obstructing the CSF flow although the cerebral parenchyma has a normal CT appearance in many cases. CNS toxoplasmosis should be ruled out in any immuno-deficient patient with hydrocephalus of unknown origin. The permanent CSF shunting may not be necessary in hydrocephalus due to CNS toxoplasmosis, and external CSF shunting may only rarely be needed. RESUME \u0000Les auteurs presentent un cas d'hydrocephalie associee a une toxoplasmose du IV eme ventricule chez un patient HIV positif, traite medicalement avec succes, sans derivation du LCS. Le mecanisme de l'hydrocephalie est une ependymite et une plexite necrosante obstruant la circulation du LCS, meme si le parenchyme cerebral apparait normal au scanner dans plusieurs cas. Une toxoplasmose du systeme nerveux central doit etre recherchee chez tout patient immunodeprime avec une hydrocephalie d'etiologie indeterminee. Une derivation permanente du LCS ne serait pas necessaire au cours de l'hydrocephalie entrant dans ce cadre. La derivation ventriculaire externe peut etre implantee dans de rares conditions. Key Words: CNS toxoplasmosis, AIDS, hydrocephalus, medical treatment, Cameroon, Afrique, Cameroun, Hydrocephalie, Toxoplasmose, VIH, SIDA African Journal of Neurological Sciences Vol.23(2) 2004","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2005-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farid Wagdi, C. Debrock, Karim Farid, B. Bouteille, P. Preux
ASSOCIATION ENTRE TRAITEMENT DE L'ASCARIDIOSE ET DIMINUTION DE LA FREQUENCE DES CRISES CHEZ LES PATIENTS EPILEPTIQUES A ALEXANDRIE (EGYPTE) RESUME Description et objectif: ce travail recherche une association entre ascaridiose et epilepsie. Methodes: une etude d'impact du traitement anti-helminthique a ete realisee dans le service de Neuropychiatrie d'un hopital general d'Alexandrie en Egypte. Resultats: 537 patients epileptiques ont ete inclus. Le niveau d'infection d'ascaridiose etait severe a modere pour 68 % d'entre eux. Apres traitement anti-helminthique, le nombre moyen de crises d'epilepsie partielle s'est reduit de 10 % (p Conclusion: cette etude donne des arguments indirects incitant a poursuivre les etudes epidemiologiques ou physiopathologiques a la recherche d'un lien causal entre ascaridiose et epilepsie. SUMMARY Background and objective: this work looks for a link between ascaridiasis and epilepsy. Methods: This work has looked for the impact of an anti-helminthic treatment on the course of epilepsy and was performed in the Neuropsychiatry department of a general hospital of Alexandria in Egypt. Results: 537 patients with epilepsy have been included. The level of ascaridiasis infection was severe to moderate for 68 % of them. After anti-helminthic treatment, the average number of partial epilepsy fits has reduced in 10 % (p Conclusion: this study gives indirect arguments prompting to continue epidemiological or pathophysiological studies in search of a correlation between ascaridiasis and epilepsy. Keywords : Afrique, ascaridiose, Egypte, epilepsie, Africa, ascaridiasis, Egypt, epilepsy African Journal of Neurological Sciences Vol.23(2) 2004
{"title":"IMPACT OF AN ANTI-HELMINTHIC TREATMENT ON THE COURSE OF EPILEPSY IN THE NEUROPSYCHIATRY DEPARTMENT OF ALEXANDRIA IN EGYPT : A LINK BETWEEN ASCARIDIASIS AND EPILEPSY ?","authors":"Farid Wagdi, C. Debrock, Karim Farid, B. Bouteille, P. Preux","doi":"10.4314/AJNS.V23I2.7554","DOIUrl":"https://doi.org/10.4314/AJNS.V23I2.7554","url":null,"abstract":"ASSOCIATION ENTRE TRAITEMENT DE L'ASCARIDIOSE ET DIMINUTION DE LA FREQUENCE DES CRISES CHEZ LES PATIENTS EPILEPTIQUES A ALEXANDRIE (EGYPTE) \u0000RESUME \u0000Description et objectif: ce travail recherche une association entre ascaridiose et epilepsie. \u0000Methodes: une etude d'impact du traitement anti-helminthique a ete realisee dans le service de Neuropychiatrie d'un hopital general d'Alexandrie en Egypte. \u0000Resultats: 537 patients epileptiques ont ete inclus. Le niveau d'infection d'ascaridiose etait severe a modere pour 68 % d'entre eux. Apres traitement anti-helminthique, le nombre moyen de crises d'epilepsie partielle s'est reduit de 10 % (p \u0000Conclusion: cette etude donne des arguments indirects incitant a poursuivre les etudes epidemiologiques ou physiopathologiques a la recherche d'un lien causal entre ascaridiose et epilepsie. SUMMARY \u0000Background and objective: this work looks for a link between ascaridiasis and epilepsy. \u0000Methods: This work has looked for the impact of an anti-helminthic treatment on the course of epilepsy and was performed in the Neuropsychiatry department of a general hospital of Alexandria in Egypt. \u0000Results: 537 patients with epilepsy have been included. The level of ascaridiasis infection was severe to moderate for 68 % of them. After anti-helminthic treatment, the average number of partial epilepsy fits has reduced in 10 % (p \u0000Conclusion: this study gives indirect arguments prompting to continue epidemiological or pathophysiological studies in search of a correlation between ascaridiasis and epilepsy. Keywords : Afrique, ascaridiose, Egypte, epilepsie, Africa, ascaridiasis, Egypt, epilepsy African Journal of Neurological Sciences Vol.23(2) 2004","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"234 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2005-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}