Introduction Febrile seizures are the most common seizure disorder in children. Most studies on the knowledge, attitude and practice towards children with febrile seizures have been taken in western countries. Little is known on the knowledge, attitude and practice of mothers regarding febrile seizures in Tripoli, Libya. Aims Most parents witnessing their child’s first febrile seizures find it a frightening experience and a significant number think that their child is going to die. In their panic parent’s initial reaction are often inappropriate. It is recommended that parents should be taught how to cope with the recurrence by explaining the pathophysiology of the condition and give written information about the condition and its managements. The aim of the audit is to assess the attitude and knowledge of parents of children with febrile seizures before and after the introduction of the information leaflets regarding febrile seizures. Method The parents of all children in the study period (2007 & 2008) admitted to Paediatric ward Al-Khadra hospital Tripoli, Libya with diagnostic code for febrile seizures were interviewed. A well prepared questionnaire was completed by parents of each child admitted with diagnostic code for febrile seizures. Total number of children admitted to the Pediatric ward in 2007 was 1506 of which 126 were diagnosed as Febrile Seizures (7.9%), and were selected randomly. Total number of children admitted to the Pediatric ward in 2008 were 1849 of which 113 were diagnosed as Febrile Seizures (6.1%), and were selected randomly. 11 out of 113 had recurrent episodes of febrile seizures. An organized and comparative prospective study was done to obtain the results before and after the introduction of the information leaflet. Results The population sample was generally a mixture of urban and rural civilians with average level of education and employment. The majority of febrile seizure cases that were admitted to our department in 2007 & 2008 were found to be of equal sex incidence. The peak age for febrile seizures in patients that were included in this study were found to be between 5-12 months representing (44%) in 2007 & (29%) in 2008. The attitude of mothers before and after the introduction of the information leaflet did not change significantly. Their practice, however, were still inappropriate. Conclusion Parents of children being treated for febrile seizures had a variety of different answers when asked to describe their action when their child had a fit. Our study suggests clues regarding parent’s anxiety and fear when witnessing a seizure. These include: Lack of Knowledge about the disease and lack of education regarding first aid and basic life support. This study is limited by the relatively small sample size. The study results do however describe prevalent views of the disease and provide indications regarding the connection between education, knowledge, and attitude of parents of children with febrile seizur
{"title":"Auditing the attitude and knowledge of parents of children with febrile seizures","authors":"Adel M. Zeglam, Suad Al-Hmadi, Asaad G. Beshish","doi":"10.4314/AJNS.V29I1","DOIUrl":"https://doi.org/10.4314/AJNS.V29I1","url":null,"abstract":"Introduction Febrile seizures are the most common seizure disorder in children. Most studies on the knowledge, attitude and practice towards children with febrile seizures have been taken in western countries. Little is known on the knowledge, attitude and practice of mothers regarding febrile seizures in Tripoli, Libya. Aims Most parents witnessing their child’s first febrile seizures find it a frightening experience and a significant number think that their child is going to die. In their panic parent’s initial reaction are often inappropriate. It is recommended that parents should be taught how to cope with the recurrence by explaining the pathophysiology of the condition and give written information about the condition and its managements. The aim of the audit is to assess the attitude and knowledge of parents of children with febrile seizures before and after the introduction of the information leaflets regarding febrile seizures. Method The parents of all children in the study period (2007 & 2008) admitted to Paediatric ward Al-Khadra hospital Tripoli, Libya with diagnostic code for febrile seizures were interviewed. A well prepared questionnaire was completed by parents of each child admitted with diagnostic code for febrile seizures. Total number of children admitted to the Pediatric ward in 2007 was 1506 of which 126 were diagnosed as Febrile Seizures (7.9%), and were selected randomly. Total number of children admitted to the Pediatric ward in 2008 were 1849 of which 113 were diagnosed as Febrile Seizures (6.1%), and were selected randomly. 11 out of 113 had recurrent episodes of febrile seizures. An organized and comparative prospective study was done to obtain the results before and after the introduction of the information leaflet. Results The population sample was generally a mixture of urban and rural civilians with average level of education and employment. The majority of febrile seizure cases that were admitted to our department in 2007 & 2008 were found to be of equal sex incidence. The peak age for febrile seizures in patients that were included in this study were found to be between 5-12 months representing (44%) in 2007 & (29%) in 2008. The attitude of mothers before and after the introduction of the information leaflet did not change significantly. Their practice, however, were still inappropriate. Conclusion Parents of children being treated for febrile seizures had a variety of different answers when asked to describe their action when their child had a fit. Our study suggests clues regarding parent’s anxiety and fear when witnessing a seizure. These include: Lack of Knowledge about the disease and lack of education regarding first aid and basic life support. This study is limited by the relatively small sample size. The study results do however describe prevalent views of the disease and provide indications regarding the connection between education, knowledge, and attitude of parents of children with febrile seizur","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"21 1","pages":"3-8"},"PeriodicalIF":0.1,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/AJNS.V29I1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70467171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gd Kapadonou, E. Fiossi-Kpadonou, E. Alagnide, Gd Avode, H. Odoulami
Description Si dans les pays industrialises, le pronostic vital, les capacites fonctionnelles et l'esperance de vie des paraplegiques se sont ameliores, en Afrique, leur devenir est encore incertain. Objectif Analyser le devenir des paraplegiques suivis en reeducation hospitaliere a Cotonou de 1999 a 2003, et apres retour a domicile. Methode c'est une etude retrospective, descriptive portant sur 40 paraplegiques adultes traites de 1999 a 2003 et reexamines en fevrier 2004 pour evaluer leur devenir. Resultats 65% des patients etaient hommes et 35% de femmes de sex-ratio 1,8 et d'âge moyen 42, 8 ans,. Les etiologies sont dominees par le traumatisme (37,5%), les tumeurs (22,5%), la hernie discale operee (22,5%). 57,5% des patients ont presente des troubles vesicosphincteriens. Spasticite et escarres ont ete frequentes chez les patients. Les niveaux lesionnels medullaires (thoraciques et lombaires hauts) ont ete de 50% et queue de cheval 50%. Neuf mois a trois ans apres leur retour a domicile, 32,5% des patients sont decedes dont 69% de causes tumorales. Parmi les survivants, 18,5% ont marche ; 28,5 % avec appareillage, 52% condamnes au fauteuil roulant. Le retour a domicile avec la participation de la famille a ete possible pour 92% ; mais 66,7% des survivants n'ont joui ni de reconversion ni de reinsertion professionnelle. Conclusion Le devenir des paraplegiques reeduques au CNHU de Cotonou a ete fortement marque par l'issue fatale. Aux survivants se sont poses des problemes de reinsertion professionnelle dont la resolution depasse le cadre restreint de la solidarite africaine. Background If in industrialized countries, vital prognosis, functional capacities and life expectancy of paraplegics improved, their becoming is still unsettled in Africa. Objective to analyse the becoming of patients with paraplegia rehabilitated at CNHU in Cotonou, from 1999 to 2003 and after their returning back home. Method It is a retrospective study aimed to be descriptive, done with 40 adults with paraplegia, followed from 1999 to 2003 and seen again in February 2004 to appreciate their becoming. Results 65% of patients were men and 35% women; sex-ratio about 1.8 and 42.8 years as average age; most of them still being in professional activity. Aetiologies were prevailed by traumatism (37. 5%), tumor (22. 5%) and operated discal hernia (22. 5%). On 57. 5% cases, urinary disorders were present with paraplegia. Spasticity and eschars were frequently developed by patients. Levels were spinal cord injuries (thoracic and lumbar high) 50% and ponytail 50%. Nine months to three years after their returning back home, 32. 5% of patients died, 69 % of them with neoplasia. 18. 5% of survivors were able to walk, 29. 5% with artificial limb supply, 52% condemned to use wheel chair. Returning back home with the participation of the family was possible for 92% of patients. Neither professional reinsertion nor reconversion was possible for 66. 7% of survivors. Concl
{"title":"Epidemiologie Et Devenir Des Paraplegiques Reeduques Au Cnhu De Cotonou","authors":"Gd Kapadonou, E. Fiossi-Kpadonou, E. Alagnide, Gd Avode, H. Odoulami","doi":"10.4314/AJNS.V26I2.7599","DOIUrl":"https://doi.org/10.4314/AJNS.V26I2.7599","url":null,"abstract":"Description \u0000Si dans les pays industrialises, le pronostic vital, les capacites fonctionnelles et l'esperance de vie des paraplegiques se sont ameliores, en Afrique, leur devenir est encore incertain.\u0000\u0000Objectif \u0000Analyser le devenir des paraplegiques suivis en reeducation hospitaliere a Cotonou de 1999 a 2003, et apres retour a domicile.\u0000\u0000Methode \u0000c'est une etude retrospective, descriptive portant sur 40 paraplegiques adultes traites de 1999 a 2003 et reexamines en fevrier 2004 pour evaluer leur devenir.\u0000\u0000Resultats \u000065% des patients etaient hommes et 35% de femmes de sex-ratio 1,8 et d'âge moyen 42, 8 ans,. Les etiologies sont dominees par le traumatisme (37,5%), les tumeurs (22,5%), la hernie discale operee (22,5%). 57,5% des patients ont presente des troubles vesicosphincteriens. Spasticite et escarres ont ete frequentes chez les patients. Les niveaux lesionnels medullaires (thoraciques et lombaires hauts) ont ete de 50% et queue de cheval 50%. Neuf mois a trois ans apres leur retour a domicile, 32,5% des patients sont decedes dont 69% de causes tumorales. Parmi les survivants, 18,5% ont marche ; 28,5 % avec appareillage, 52% condamnes au fauteuil roulant. Le retour a domicile avec la participation de la famille a ete possible pour 92% ; mais 66,7% des survivants n'ont joui ni de reconversion ni de reinsertion professionnelle.\u0000\u0000Conclusion \u0000Le devenir des paraplegiques reeduques au CNHU de Cotonou a ete fortement marque par l'issue fatale. Aux survivants se sont poses des problemes de reinsertion professionnelle dont la resolution depasse le cadre restreint de la solidarite africaine.\u0000\u0000 Background \u0000If in industrialized countries, vital prognosis, functional capacities and life expectancy of paraplegics improved, their becoming is still unsettled in Africa.\u0000\u0000Objective \u0000to analyse the becoming of patients with paraplegia rehabilitated at CNHU in Cotonou, from 1999 to 2003 and after their returning back home.\u0000\u0000Method \u0000It is a retrospective study aimed to be descriptive, done with 40 adults with paraplegia, followed from 1999 to 2003 and seen again in February 2004 to appreciate their becoming.\u0000\u0000Results \u000065% of patients were men and 35% women; sex-ratio about 1.8 and 42.8 years as average age; most of them still being in professional activity. Aetiologies were prevailed by traumatism (37. 5%), tumor (22. 5%) and operated discal hernia (22. 5%). On 57. 5% cases, urinary disorders were present with paraplegia. Spasticity and eschars were frequently developed by patients. Levels were spinal cord injuries (thoracic and lumbar high) 50% and ponytail 50%. Nine months to three years after their returning back home, 32. 5% of patients died, 69 % of them with neoplasia. 18. 5% of survivors were able to walk, 29. 5% with artificial limb supply, 52% condemned to use wheel chair. Returning back home with the participation of the family was possible for 92% of patients. Neither professional reinsertion nor reconversion was possible for 66. 7% of survivors.\u0000\u0000Concl","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"26 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2008-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70466143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Njamnshi, V. Sini, V. Djientcheu, P. Ongolo-Zogo, Y. Mapoure, F. Yepnjio, T. Echouffo, R. Zebaze, R. Meli, G. Atchou, L. Dongmo, W. Muna
Introduction An epileptic area with very high endemicity has been described in Bilomo, a village near Yaounde, the capital city of Cameroon. Purpose This study was carried out to determine some of the risk and precipitating factors associated with epilepsy in Bilomo. Patients and Methods This was part of a community-based door-to-door survey in 1999, using the survey instrument developed by the Institute of Neurological Epidemiology and Tropical Neurology of Limoges, the Pan-African Association of Neurological Sciences and the International League Against Epilepsy. Neurological evaluation and confirmation of epilepsy was done by consultant neurologists. Results 93 cases of epilepsy were confirmed in the study population of 1898 subjects, giving a prevalence rate of epilepsy in Bilomo of 4.9%. The main risk factor for epilepsy was a positive family history (63.44%). The neurological examination was abnormal in 22.6% of patients. Mental retardation was found in 17.2%, psychological disorders in 16.1%, a pyramidal syndrome (unilateral or bilateral weakness with spasticity and Babinski sign) in 6.4%, language disorders in 4.3%, and a cerebellar syndrome in 1.1% of the patients. Subcutaneous nodules were observed in 13 patients (14%). Pruriginous dermatoses were found in 23 patients (24.7%). A possible aetiologic factor was found in 66 patients (71%). The other risk factors included prenatal (8.6%) and perinatal (19.4%) factors, central nervous system infections (9.7%) and head injury (5.4%). Conclusion The data from this preliminary study suggests that in Bilomo village, the risk factors associated with epilepsy include both hereditary and acquired factors and we postulate that there may be a complex interplay of these factors in the aetiogenesis of epilepsy in this area. These results call for more studies in an attempt to determine the aetiologic factors and more importantly, the interplay between these factors that is responsible for making epilepsy endemic in this area. Such information is vital for an effective national epilepsy control programme. Introduction Une zone de forte endemicite epileptique a ete decrite dans le village de Bilomo, non loin de Yaounde, la capitale du Cameroun. But Cette etude avait pour but de decrire les facteurs de risque et de precipitation de l'epilepsie dans le village de Bilomo. Patients et Methodes Notre etude fait partie d'une etude communautaire basee sur une enquete porte-a-porte effectuee en 1999, utilisant le questionnaire developpee par l'Institut d'Epidemiologie Neurologique et de Neurologie Tropicale (IENT) a Limoges, l'Association Pan Africaine des Sciences Neurologiques et la Ligue Internationale contre l'Epilepsie. L'evaluation neurologique et la confirmation de l'epilepsie ont ete faites par les neurologues consultants. Resultats 93 cas d'epilepsie ont ete confirmes dans une population de 1898 sujets dans le village, ce qui donne une prevalence de l'epilepsie dans ce village de 4,9%.
在喀麦隆首都雅温得附近的一个村庄Bilomo报告了一个发病率非常高的癫痫区。目的本研究旨在确定Bilomo地区癫痫的一些危险因素和诱发因素。这是1999年以社区为基础的挨家挨户调查的一部分，使用的是利摩日神经流行病学和热带神经病学研究所、泛非神经科学协会和国际抗癫痫联盟开发的调查工具。癫痫的神经学评估和确认由神经科顾问医师完成。结果研究人群1898例确诊癫痫93例，比洛莫区癫痫患病率为4.9%。癫痫的主要危险因素为阳性家族史(63.44%)。22.6%的患者神经系统检查异常。17.2%的患者存在智力障碍，16.1%的患者存在心理障碍，6.4%的患者存在锥体综合征(单侧或双侧无力伴痉挛和巴宾斯基征)，4.3%的患者存在语言障碍，1.1%的患者存在小脑综合征。皮下结节13例(14%)。瘙痒性皮肤病23例(24.7%)。66例(71%)患者发现可能的病因。其他危险因素包括产前因素(8.6%)和围产期因素(19.4%)、中枢神经系统感染(9.7%)和头部损伤(5.4%)。结论本初步研究数据表明，在Bilomo村，与癫痫相关的危险因素包括遗传因素和获得性因素，我们推测这些因素在该地区癫痫的病因发生中可能存在复杂的相互作用。这些结果要求进行更多的研究，以试图确定病因因素，更重要的是，确定这些因素之间的相互作用，这些因素导致癫痫在该地区流行。这些信息对于制定有效的国家癫痫控制规划至关重要。喀麦隆首都雅温得附近比洛莫村癫痫流行区。但是，我们的确有很多事情要做，但是我们的确有很多事情要做，我们的确有很多事情要做。患者与方法:1999年，患者与患者的临床研究与临床研究、患者与患者的临床研究、患者与患者的临床研究、患者与患者的临床研究;利摩日神经病学和热带神经病学流行病学研究所(IENT)、泛非神经病学科学协会和国际癫痫控制联盟(lligue)的问卷调查。神经病学的评估和癫痫的确认与神经科顾问的诊断一致。结果93例癫痫确诊病例中有1例确诊病例，98例病例中有1例确诊病例，4例病例中有1例确诊病例，4例病例中有1例确诊病例。风险性因素合并癫痫症家族史阳性(63.3%)。L检查神经功能异常的患者占22.6%。精神发育迟滞者为17.2%，心理障碍者为16.1%，锥体综合征者为6.4%，语言障碍者为4.3%，小脑综合征者为1.1%。报告中提到的这些问题中，有12例患者在检查前出现了存在的症状或运动障碍。原发性皮肤结节复发13例(14.0%)。原发性皮肤病患者23例(24.7%)。66例(71.0%)患者的病因不明确。特征因素:产前因素(8.6%)，围产期因素(19.4%)，中枢神经系统感染(9.7%)和创伤性创伤(5.4%)。结论未发现癫痫性痴呆的发病因素、发病因素、癫痫性痴呆的发病因素、遗传因素和习得因素之间存在关联。本研究提示，在癫痫脑区发病的不同因素中，癫痫脑区的发病机制可能不存在单一的相互作用复合体。这将是必要和有效的措施，包括预防癫痫的措施、预防癫痫地方性流行的责任人、预防癫痫地区的责任人、预防癫痫的责任人、预防癫痫的责任人、预防癫痫的责任人和预防癫痫的责任人。关键词:非洲，喀麦隆，癫痫，危险因素，农村地区非洲神经科学杂志Vol. 26 (2) 2007: pp. 18-26
{"title":"Risk Factors Associated With Epilepsy In A Rural Area In Cameroon: A Preliminary Study","authors":"A. Njamnshi, V. Sini, V. Djientcheu, P. Ongolo-Zogo, Y. Mapoure, F. Yepnjio, T. Echouffo, R. Zebaze, R. Meli, G. Atchou, L. Dongmo, W. Muna","doi":"10.4314/AJNS.V26I2.7595","DOIUrl":"https://doi.org/10.4314/AJNS.V26I2.7595","url":null,"abstract":"Introduction \u0000An epileptic area with very high endemicity has been described in Bilomo, a village near Yaounde, the capital city of Cameroon.\u0000\u0000Purpose \u0000This study was carried out to determine some of the risk and precipitating factors associated with epilepsy in Bilomo.\u0000\u0000Patients and Methods \u0000This was part of a community-based door-to-door survey in 1999, using the survey instrument developed by the Institute of Neurological Epidemiology and Tropical Neurology of Limoges, the Pan-African Association of Neurological Sciences and the International League Against Epilepsy. Neurological evaluation and confirmation of epilepsy was done by consultant neurologists.\u0000\u0000Results \u000093 cases of epilepsy were confirmed in the study population of 1898 subjects, giving a prevalence rate of epilepsy in Bilomo of 4.9%. The main risk factor for epilepsy was a positive family history (63.44%). The neurological examination was abnormal in 22.6% of patients. Mental retardation was found in 17.2%, psychological disorders in 16.1%, a pyramidal syndrome (unilateral or bilateral weakness with spasticity and Babinski sign) in 6.4%, language disorders in 4.3%, and a cerebellar syndrome in 1.1% of the patients. Subcutaneous nodules were observed in 13 patients (14%). Pruriginous dermatoses were found in 23 patients (24.7%). A possible aetiologic factor was found in 66 patients (71%). The other risk factors included prenatal (8.6%) and perinatal (19.4%) factors, central nervous system infections (9.7%) and head injury (5.4%).\u0000\u0000Conclusion \u0000The data from this preliminary study suggests that in Bilomo village, the risk factors associated with epilepsy include both hereditary and acquired factors and we postulate that there may be a complex interplay of these factors in the aetiogenesis of epilepsy in this area. These results call for more studies in an attempt to determine the aetiologic factors and more importantly, the interplay between these factors that is responsible for making epilepsy endemic in this area. Such information is vital for an effective national epilepsy control programme.\u0000\u0000 Introduction \u0000Une zone de forte endemicite epileptique a ete decrite dans le village de Bilomo, non loin de Yaounde, la capitale du Cameroun.\u0000\u0000But \u0000Cette etude avait pour but de decrire les facteurs de risque et de precipitation de l'epilepsie dans le village de Bilomo.\u0000\u0000Patients et Methodes \u0000Notre etude fait partie d'une etude communautaire basee sur une enquete porte-a-porte effectuee en 1999, utilisant le questionnaire developpee par l'Institut d'Epidemiologie Neurologique et de Neurologie Tropicale (IENT) a Limoges, l'Association Pan Africaine des Sciences Neurologiques et la Ligue Internationale contre l'Epilepsie. L'evaluation neurologique et la confirmation de l'epilepsie ont ete faites par les neurologues consultants.\u0000\u0000Resultats \u000093 cas d'epilepsie ont ete confirmes dans une population de 1898 sujets dans le village, ce qui donne une prevalence de l'epilepsie dans ce village de 4,9%.","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"26 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2008-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70466025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Lagunju, C. Okolo, Be Ebruke, K. Emejulu, A. Malomo, E. Akang, M. Shokunbi
Tuberous sclerosis (TS) is a genetic disorder characterised by the triad of cutaneous lesions, epilepsy and mental retardation. TS is known to have a wide clinical spectrum, with some affected individuals having only the cutaneous manifestations, normal IQ and no seizures, while others are severely affected having intractable seizures and profound mental retardation. A report of two Nigerian children with TS managed at the University College Hospital, Ibadan, Nigeria is presented. Both had severe neurological manifestations of the disease and a sub clinical affectation was found in a first degree relative in one of them. African Journal of Neurological Sciences Vol. 26 (2) 2007: pp. 102-108
结节性硬化症(TS)是一种以皮肤病变、癫痫和智力迟钝为特征的遗传性疾病。已知TS具有广泛的临床范围，一些患者只有皮肤表现，智商正常，没有癫痫发作，而另一些患者则严重影响顽固性癫痫发作和深度智力迟钝。本文介绍了在尼日利亚伊巴丹大学学院医院管理的两名患有TS的尼日利亚儿童的报告。两人都有严重的神经系统症状，其中一人的一级亲属有亚临床症状。非洲神经科学杂志Vol. 26 (2) 2007: pp. 102-108
{"title":"Severe Neurological Involvement In Tuberous Sclerosis: A Report Of Two Cases And A Review Of The African Literature","authors":"I. Lagunju, C. Okolo, Be Ebruke, K. Emejulu, A. Malomo, E. Akang, M. Shokunbi","doi":"10.4314/AJNS.V26I2.7604","DOIUrl":"https://doi.org/10.4314/AJNS.V26I2.7604","url":null,"abstract":"Tuberous sclerosis (TS) is a genetic disorder characterised by the triad of cutaneous lesions, epilepsy and mental retardation. TS is known to have a wide clinical spectrum, with some affected individuals having only the cutaneous manifestations, normal IQ and no seizures, while others are severely affected having intractable seizures and profound mental retardation. A report of two Nigerian children with TS managed at the University College Hospital, Ibadan, Nigeria is presented. Both had severe neurological manifestations of the disease and a sub clinical affectation was found in a first degree relative in one of them.\u0000\u0000 African Journal of Neurological Sciences Vol. 26 (2) 2007: pp. 102-108","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"26 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2008-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70466218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. N. Oka, E. Broalet, M. Kakou, P. Broalet, A. Haidara, R. N’Guessan, L. Varlet, G. Dechambenoit, V. Bazeze
Objective To report our experience in the management of intracranial meningiomas. Methods Ninety-six (96) patients were treated for intracranial meningiomas in Abidjan between 1991 and 2001, confirmed by neuropathological examination. Results Meningiomas represented 33.43% of intracranial tumors. The average age of our patients was 43 years, from 7 to 72 years-old with a predominance of women: sex ratio 3/2. Headaches were the most frequent sign. Post operative mortality was 12. 63%. Meningothelial meningioma was the most frequent (55.78%) histopathological entity. Conclusion Meningioma represented the most frequent intracranial tumor in Ivory Coast. Our patients were young. More prospective studies - clinical, biology, neuroimaging - are request in order to appreciate all the features of this pathology. Objectif Presenter les particularites epidemiologiques, cliniques et therapeutiques des meningiomes intracrâniens en milieu sous medicalise, a travers l'experience ivoirienne. Materiel et Methode Il s'agit d'une etude retrospective d'une serie de 96 cas de meningiomes intracrâniens traites au service de neurochirurgie d'Abidjan de 1991 a 2001.Le diagnostic pre chirurgical ou avant la biopsie fait par le scanner etait confirme par l'examen neuro-pathologique. Le suivi postoperatoire a ete clinique et quelquefois un examen tomodensitometrique a ete realise. Resultats Les meningiomes ont represente 33,43% des tumeurs intracrâniennes. La moyenne d'âge au moment du diagnostic etait de 43 ans avec des extremes de 07 a 72 ans. Le sexe feminin a predomine avec un sex-ratio de 3/2. Le tableau clinique etait domine par les cephalees. Le delai precedant le diagnostic etait d'environ 22 mois. Les meningiomes de la convexite etaient les plus frequents (47,36%). Dans la majorite des cas le diametre tumoral se situait entre 3 cm et 6 cm. L'exerese chirurgicale a constitue l'essentiel du traitement avec une mortalite operatoire de 12,63%. Les meningiomes usuels de type meningothelial ont predomine (55,78%). Conclusion Les meningiomes ont represente les plus frequents des tumeurs intracrâniennes en milieu ivoirien. Des etudes ulterieures africaines epidemiologiques permettront de le verifier. Les meningiomes ont ete diagnostiques chez des patients relativement plus jeunes (43 ans) que ceux des pays occidentaux (58 ans). Depuis l'avenement du scanner des services de neurochirurgie et de neuropathologie, les meningiomes ne posent moins de probleme de diagnostic. Les unites de recherche sur l'oncogenese et sur les therapeutiques complementaires a la chirurgie sont encore inexistantes Keywords : intracranial Meningioma / cerebral Tumor / Abidjan. African Journal of Neurological Sciences Vol. 27 (1) 2008: pp. 31-35
目的总结颅内脑膜瘤的治疗经验。方法1991 ~ 2001年在阿比让接受颅内脑膜瘤治疗的96例患者经神经病理学检查证实。结果脑膜瘤占颅内肿瘤的33.43%。患者平均年龄43岁，7 ~ 72岁，女性居多，性别比3/2。头痛是最常见的症状。术后死亡率为12。63%。脑膜上皮性脑膜瘤是最常见的组织病理实体(55.78%)。结论脑膜瘤是科特迪瓦最常见的颅内肿瘤。我们的病人都很年轻。需要更多的前瞻性研究-临床，生物学，神经影像学-以了解该病理的所有特征。目的介绍脑膜组的特点、流行病学特点、临床特点和治疗方法，以及在科特迪瓦的经验。材料与方法:回顾性分析1991 ~ 2001年阿比让神经外科手术中96例脑膜组病例的资料。术前诊断、活体组织检查、扫描仪检查、神经病理检查均可确诊。术后随访:1、术后随访:1、术后复查:1、术后复查:1、术后复查:1、术后复查:1、术后复查:结果脑膜小体占脑膜内肿瘤的33.43%。La moyenne d ' ' ge au moment du diagnostic etaet为43岁，平均年龄为07岁，平均年龄为72岁，男性占主导地位，平均年龄为3/2。这是一种典型的治疗方法。Le delai先例Le诊断特征d ' s环境22 mois。Les meningiomes de la convexite etaient Les plus frequents(47.36%)。主要肿瘤部位直径在3 ~ 6 cm之间。L ' exerese chirurgicale构建L ' essentiel du traitement用一个mortalite operatoire de 12 63%。脑膜瘤通常为脑膜上皮型(55,78%)。结论脑膜组并不是常见的脑膜组内肿瘤。他研究了不同的文化，非洲流行病学，并进行了验证。脑膜瘤不能诊断为与患者关系相关的疾病(43例)，不能诊断为与西方疾病相关的疾病(58例)。神经外科、神经病理学、脑膜组影像学检查、脑膜组影像学检查、脑膜组影像学检查。【关键词】颅内脑膜瘤/脑肿瘤/阿比让。非洲神经科学杂志Vol. 27 (1) 2008: pp. 31-35
{"title":"Les méningiomes intrâcraniens en milieu ivoirien. Étude d'une serie chirurgicale","authors":"D. N. Oka, E. Broalet, M. Kakou, P. Broalet, A. Haidara, R. N’Guessan, L. Varlet, G. Dechambenoit, V. Bazeze","doi":"10.4314/AJNS.V27I1.7611","DOIUrl":"https://doi.org/10.4314/AJNS.V27I1.7611","url":null,"abstract":"Objective \u0000To report our experience in the management of intracranial meningiomas.\u0000\u0000Methods \u0000Ninety-six (96) patients were treated for intracranial meningiomas in Abidjan between 1991 and 2001, confirmed by neuropathological examination.\u0000\u0000Results \u0000Meningiomas represented 33.43% of intracranial tumors. The average age of our patients was 43 years, from 7 to 72 years-old with a predominance of women: sex ratio 3/2. Headaches were the most frequent sign. Post operative mortality was 12. 63%. Meningothelial meningioma was the most frequent (55.78%) histopathological entity.\u0000\u0000Conclusion \u0000Meningioma represented the most frequent intracranial tumor in Ivory Coast. Our patients were young. More prospective studies - clinical, biology, neuroimaging - are request in order to appreciate all the features of this pathology.\u0000 Objectif \u0000Presenter les particularites epidemiologiques, cliniques et therapeutiques des meningiomes intracrâniens en milieu sous medicalise, a travers l'experience ivoirienne.\u0000\u0000Materiel et Methode \u0000Il s'agit d'une etude retrospective d'une serie de 96 cas de meningiomes intracrâniens traites au service de neurochirurgie d'Abidjan de 1991 a 2001.Le diagnostic pre chirurgical ou avant la biopsie fait par le scanner etait confirme par l'examen neuro-pathologique. Le suivi postoperatoire a ete clinique et quelquefois un examen tomodensitometrique a ete realise.\u0000\u0000Resultats \u0000Les meningiomes ont represente 33,43% des tumeurs intracrâniennes. La moyenne d'âge au moment du diagnostic etait de 43 ans avec des extremes de 07 a 72 ans. Le sexe feminin a predomine avec un sex-ratio de 3/2. Le tableau clinique etait domine par les cephalees. Le delai precedant le diagnostic etait d'environ 22 mois. Les meningiomes de la convexite etaient les plus frequents (47,36%). Dans la majorite des cas le diametre tumoral se situait entre 3 cm et 6 cm. L'exerese chirurgicale a constitue l'essentiel du traitement avec une mortalite operatoire de 12,63%. Les meningiomes usuels de type meningothelial ont predomine (55,78%).\u0000\u0000Conclusion \u0000Les meningiomes ont represente les plus frequents des tumeurs intracrâniennes en milieu ivoirien. Des etudes ulterieures africaines epidemiologiques permettront de le verifier. Les meningiomes ont ete diagnostiques chez des patients relativement plus jeunes (43 ans) que ceux des pays occidentaux (58 ans). Depuis l'avenement du scanner des services de neurochirurgie et de neuropathologie, les meningiomes ne posent moins de probleme de diagnostic. Les unites de recherche sur l'oncogenese et sur les therapeutiques complementaires a la chirurgie sont encore inexistantes\u0000 Keywords : intracranial Meningioma / cerebral Tumor / Abidjan. African Journal of Neurological Sciences Vol. 27 (1) 2008: pp. 31-35","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"27 1","pages":"57-66"},"PeriodicalIF":0.1,"publicationDate":"2008-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70466360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background This hospital-based study aimed to evaluate the frequency and diagnostic pattern of epilepsy in our locality among population with age range from birth to 18 years. Methods 127 patients out of a total of 565 regularly attended the out-patient epilepsy clinic, were included in this study over 6 months period. Results At the time of interview, 48% had age ranges from 12-18 years, 78% were rural residents and 62.2% were illiterate. About 70% had age at onset of 5.9±3.5 years. Parental consanguinity was reported in 41%. Family history of epilepsy was reported in 17.3%. About 80% reported no etiology for epilepsy (idiopathic/cryptogenic group). CNS infection (68%), perinatal complications (20%) and head trauma (12%) were identified in the symptomatic group. Mental retardation was reported in 66.7%. Febrile convulsion was reported in 10.2%. Normal EEG was reported in 31.5%. About 48% had localization-related epilepsy while 42% and 9.5% had generalized and undetermined epilepsies. Frontal and temporal foci were common sites for producing epileptic discharges (37.7% for each). The generalized tonic-clonic seizures were frequent in generalized epilepsy (72.1%). Rolandic epilepsy was the most frequent type of age specific epileptic syndrome (26.9%). Conclusion Our study is considered a preliminary review for population-based epidemiological studies in childhood epilepsy in Upper Egypt. This will be of value in planning early prevention and management with proper revision of AEDs according to the available resources. Objectif Etudier la frequence et les aspects diagnostiques d'une serie hospitaliere allant de la naissance a 18 ans, dans notre localite Methodes 127 patients sur une population de 565 vus en consultation d'epilepsie en ambulatoire ont ete inclus ans cette serie Resultats 48% des patients avaient entre 12-18 ans, 78% etaient issues d'une population rurale et 62% etaient illettres. Environ 70% estimaient le debut de leur maladie a 5,9+3,5 ans. Une consanguinite etait retrouvee dans 41% des cas.Des antecedents familiaux d'epilepsie etaient retrouves dans 41% des cas. Aucune etiologie etait objectivee dans 80% des cas. Une infection du systeme nerveux central (68%), des complications perinatales (20%), et un traumatisme crânien (12%) etaient identifies dans le groupe symptomatique. Un retard mental etait observe dans 66,7% des cas et les convulsions febriles, 10,2%. La normalite de l'EEG constituait 31,5% des patiens. 48% avaient une focalisation de l'epilepsie tandis que 42% et 9,5% etaient respectivement generalises et indetermines. La topographie frontale et temporale etaient les zones presentant le plus de decharges paroxystiques (37.7%). Les crises tonico-cloniques repondaient frequentes et repondaient a une epilepsie generalisee. L'epilepsie rolandiqe etait le type le plus frequent de l'epilepsie - syndrome. Conclusion Notre etude est consideree comme etant preliminaire et portait sur une population d'enfants epile
本研究以医院为基础，旨在评估本区出生至18岁人群中癫痫的发病率和诊断模式。方法选取565例常规门诊癫痫患者中的127例进行为期6个月的研究。结果受访时年龄在12-18岁之间的占48%，农村居民占78%，文盲占62.2%。发病年龄5.9±3.5岁，约占70%。41%的人有亲本血缘关系。有癫痫家族史的占17.3%。约80%的癫痫无病因(特发性/隐源性组)。症状组主要有中枢神经系统感染(68%)、围产期并发症(20%)和头部外伤(12%)。66.7%为智力低下。10.2%为热性惊厥。脑电图正常者占31.5%。约48%的患者患有定位相关性癫痫，42%和9.5%的患者患有全身性和未确定的癫痫。额叶和颞叶是产生癫痫放电的常见部位(各占37.7%)。全身性强直阵挛发作在全身性癫痫中较为常见(72.1%)。罗兰癫痫是最常见的年龄特异性癫痫综合征类型(26.9%)。结论本研究是对上埃及地区儿童癫痫人群流行病学研究的初步回顾。这将有助于规划早期预防和管理，并根据现有资源对aed进行适当修订。目的:探讨本院发病、发病频次、发病时间、发病地点等5个方面的诊断方法，对本院发病、发病时间、发病时间、发病时间、发病时间、发病时间等127例患者进行调查，分析本院发病、发病时间、发病时间、发病时间、发病时间、发病时间、发病时间、发病时间、发病时间、发病时间、发病时间、发病时间、发病时间、发病时间、发病时间、发病时间、发病时间等。环境估计70%的人在5、9+3、5年的时间里首次发病，1年的时间里有41%的人发病。熟悉的前因导致癫痫发作的发生率为41%。该病的病因学指标为80%。1例中枢神经系统感染(68%)，6例围产期并发症(20%)，1例外伤性颅脑损伤(12%)。精神发育迟滞者66.7%，惊厥、发热者10.2%。脑电图正常者占31.5%。48%的癫痫患者有单一聚焦，42%的癫痫患者有泛化，9.5%的癫痫患者有不确定。地形前缘区和颞区均表现为阵发性放电伴放电区(37.7%)。强直性慢性发作的发作频率为1次，癫痫全病患者为1次。癫痫病可分为癫痫型和频繁的癫痫综合征。结论对上埃及地区儿童癫痫病发病人群进行了初步研究。这些患者在使用“单一预防”、“非治疗”、“抗癫痫药物”和“可使用资源”等方面存在偏差。关键词:癫痫，流行病学，埃及，医院为基础/埃及，流行病学，癫痫，医院非洲神经科学杂志Vol. 26 (1) 2007: pp. 33-44
{"title":"Pattern Of Epilepsy In Childhood And Adolescence : A Hospital-Based Study","authors":"Kandil, W. Ahmed, A. Sayed, S. Hamed","doi":"10.4314/AJNS.V26I1.7592","DOIUrl":"https://doi.org/10.4314/AJNS.V26I1.7592","url":null,"abstract":"Background \u0000This hospital-based study aimed to evaluate the frequency and diagnostic pattern of epilepsy in our locality among population with age range from birth to 18 years.\u0000\u0000Methods \u0000127 patients out of a total of 565 regularly attended the out-patient epilepsy clinic, were included in this study over 6 months period.\u0000\u0000Results \u0000At the time of interview, 48% had age ranges from 12-18 years, 78% were rural residents and 62.2% were illiterate. About 70% had age at onset of 5.9±3.5 years. Parental consanguinity was reported in 41%. Family history of epilepsy was reported in 17.3%. About 80% reported no etiology for epilepsy (idiopathic/cryptogenic group). CNS infection (68%), perinatal complications (20%) and head trauma (12%) were identified in the symptomatic group. Mental retardation was reported in 66.7%. Febrile convulsion was reported in 10.2%. Normal EEG was reported in 31.5%. About 48% had localization-related epilepsy while 42% and 9.5% had generalized and undetermined epilepsies. Frontal and temporal foci were common sites for producing epileptic discharges (37.7% for each). The generalized tonic-clonic seizures were frequent in generalized epilepsy (72.1%). Rolandic epilepsy was the most frequent type of age specific epileptic syndrome (26.9%).\u0000\u0000Conclusion \u0000Our study is considered a preliminary review for population-based epidemiological studies in childhood epilepsy in Upper Egypt. This will be of value in planning early prevention and management with proper revision of AEDs according to the available resources.\u0000\u0000 Objectif \u0000Etudier la frequence et les aspects diagnostiques d'une serie hospitaliere allant de la naissance a 18 ans, dans notre localite\u0000\u0000Methodes \u0000127 patients sur une population de 565 vus en consultation d'epilepsie en ambulatoire ont ete inclus ans cette serie\u0000\u0000Resultats \u000048% des patients avaient entre 12-18 ans, 78% etaient issues d'une population rurale et 62% etaient illettres. Environ 70% estimaient le debut de leur maladie a 5,9+3,5 ans. Une consanguinite etait retrouvee dans 41% des cas.Des antecedents familiaux d'epilepsie etaient retrouves dans 41% des cas. Aucune etiologie etait objectivee dans 80% des cas. Une infection du systeme nerveux central (68%), des complications perinatales (20%), et un traumatisme crânien (12%) etaient identifies dans le groupe symptomatique. Un retard mental etait observe dans 66,7% des cas et les convulsions febriles, 10,2%. La normalite de l'EEG constituait 31,5% des patiens. 48% avaient une focalisation de l'epilepsie tandis que 42% et 9,5% etaient respectivement generalises et indetermines. La topographie frontale et temporale etaient les zones presentant le plus de decharges paroxystiques (37.7%). Les crises tonico-cloniques repondaient frequentes et repondaient a une epilepsie generalisee. L'epilepsie rolandiqe etait le type le plus frequent de l'epilepsie - syndrome.\u0000\u0000Conclusion \u0000Notre etude est consideree comme etant preliminaire et portait sur une population d'enfants epile","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"26 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2008-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose Neurosyphilis is an uncommon disease. Although syphilis may promote the transmission of HIV the converse may not be true. The neuro-radiology of neurosyphilis is limited to two case series and several case reports. Our series of patients were reviewed to describe the clinical and radiological findings. Method A retrospective chart review from 1994 to 2005 was done and demographic, clinical, laboratory and radiological findings were extracted. Patients HIV status was also recorded. Patients who satisfied the criteria for the diagnosis of neurosyphilis with the exclusion of alternate diagnoses were included. Results Fifty-three patients were evaluated but only 41 charts were available for review. Thirty-nine of these had radiological data. The clinical spectrum included asymptomatic patients, strokes, dementia, cranial nerve palsies, spinal cord syndromes and polyradiculopathy. Imaging changes included normal findings, infarcts, meningeal based mass lesions, spinal intra-medullary hyper-intensities, cranial nerve enhancement and intra-medullary enhancing mass lesions. There was no difference in CSF cellular or chemistry findings between those with neurosyphilis who were HIV positive and those who were HIV negative. Amongst the patients where follow up was available most improved regardless of HIV status. Conclusion Neurosyphilis has protean manifestations and can affect any central neurological system. The pathogenesis varies from inflammatory mass lesions to vascular occlusion and inflammatory damage. Syphilis should be an aetiological consideration in any neurological presentation where another cause is not obvious. The radiological features are not specific and would be seen with many inflammatory aetiologies affecting the CNS. The CSF picture is similar regardless of HIV status and patients should be managed similarly regardless of their HIV status. Objectif La neurosyphilis est une maladie peu commune. Bien que la syphilis puisse promouvoir la transmission du HIV, l'inverse n'est pas vrai. Les aspects neuromatologiques de la neurosyphilis sont extremement rares , limitees a deux series et la publication de quelques cas. Notre objectif est de revoir les aspects cliniques et radiologiques de nos patients, Methode Il s'agit d'une etude retrospectives allant de 1994 a 2005 avec prise en compte des aspects demographiques, cliniques, biologiques et radiologiques. Les patients VIH positifs ont ete inclus dans l'etude, Resultat 53 patients ont ete evalues mais seuls 41 dossiers ont pu etre etudies. 39 de ces donnees disposaient d'informations radiologiques exploitables. Le tableau clinique etait variable : patient asymptomatique, AVC, demence, paralysie des nerfs crâniens, atteinte medullaire et polyradiculopathie. Les aspects a l'imagerie etaient egalement proteiformes : aspect normal, infarcissement, masses expansives meningees, hypersignaux intramedullaires, rehaussement des nerfs crâniens et tumeur intra-medullaire . Il n'y a
{"title":"Neurosyphilis: A Clinico- Radiological Study","authors":"V. Patel, A. Motala, C. Connally, I. Burger","doi":"10.4314/AJNS.V27I1.7613","DOIUrl":"https://doi.org/10.4314/AJNS.V27I1.7613","url":null,"abstract":"Purpose \u0000Neurosyphilis is an uncommon disease. Although syphilis may promote the transmission of HIV the converse may not be true. The neuro-radiology of neurosyphilis is limited to two case series and several case reports. Our series of patients were reviewed to describe the clinical and radiological findings.\u0000\u0000Method \u0000A retrospective chart review from 1994 to 2005 was done and demographic, clinical, laboratory and radiological findings were extracted. Patients HIV status was also recorded. Patients who satisfied the criteria for the diagnosis of neurosyphilis with the exclusion of alternate diagnoses were included.\u0000\u0000Results \u0000Fifty-three patients were evaluated but only 41 charts were available for review. Thirty-nine of these had radiological data. The clinical spectrum included asymptomatic patients, strokes, dementia, cranial nerve palsies, spinal cord syndromes and polyradiculopathy. Imaging changes included normal findings, infarcts, meningeal based mass lesions, spinal intra-medullary hyper-intensities, cranial nerve enhancement and intra-medullary enhancing mass lesions. There was no difference in CSF cellular or chemistry findings between those with neurosyphilis who were HIV positive and those who were HIV negative. Amongst the patients where follow up was available most improved regardless of HIV status.\u0000\u0000Conclusion \u0000Neurosyphilis has protean manifestations and can affect any central neurological system. The pathogenesis varies from inflammatory mass lesions to vascular occlusion and inflammatory damage. Syphilis should be an aetiological consideration in any neurological presentation where another cause is not obvious. The radiological features are not specific and would be seen with many inflammatory aetiologies affecting the CNS. The CSF picture is similar regardless of HIV status and patients should be managed similarly regardless of their HIV status.\u0000\u0000 Objectif \u0000La neurosyphilis est une maladie peu commune. Bien que la syphilis puisse promouvoir la transmission du HIV, l'inverse n'est pas vrai. Les aspects neuromatologiques de la neurosyphilis sont extremement rares , limitees a deux series et la publication de quelques cas. Notre objectif est de revoir les aspects cliniques et radiologiques de nos patients,\u0000\u0000Methode \u0000Il s'agit d'une etude retrospectives allant de 1994 a 2005 avec prise en compte des aspects demographiques, cliniques, biologiques et radiologiques. Les patients VIH positifs ont ete inclus dans l'etude,\u0000\u0000Resultat \u000053 patients ont ete evalues mais seuls 41 dossiers ont pu etre etudies. 39 de ces donnees disposaient d'informations radiologiques exploitables. Le tableau clinique etait variable : patient asymptomatique, AVC, demence, paralysie des nerfs crâniens, atteinte medullaire et polyradiculopathie. Les aspects a l'imagerie etaient egalement proteiformes : aspect normal, infarcissement, masses expansives meningees, hypersignaux intramedullaires, rehaussement des nerfs crâniens et tumeur intra-medullaire . Il n'y a","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"27 1","pages":"73-84"},"PeriodicalIF":0.1,"publicationDate":"2008-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70466398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Broalet, A. Haidara, Y. Zunon-Kipré, D. N. Oka, H. N'Da, A. Jibia, M. Kakou, G. Varlet, V. Bazeze
Introduction Les tumeurs cerebrales de l'enfant representent les tumeurs solides pediatriques les plus frequentes, mais leur incidence reste meconnue en Afrique subsaharienne ou se pose un probleme de retard diagnostique et de suivi. Objectif Evaluer l'incidence et la distribution de ces tumeurs et presenter les particularites de prise en charge afin d'ameliorer leur pronostic. Materiels et methodes Etude retrospective effectuee dans le service de Neurochirurgie de janvier 1995 a decembre 2006 incluant les patients hospitalises pour une tumeur cerebrale et dont l'âge variait entre 0 et 15 ans revolus. Le scanner a constitue le seul moyen de diagnostic pre-operatoire. Pour chaque patient, les caracteristiques epidemiologiques, cliniques, paracliniques et les modalites de prise en charge ont ete analysees. Resultats Les tumeurs cerebrales de l'enfant (57 cas) representaient 15,74% de toutes les tumeurs cerebrales (362 cas) avec un sex-ratio de 1/2 (18 garcons et 27 filles) et un âge moyen de 8 ans et demi. Le delai de prise en charge a ete de 289 jours en moyenne. Les cephalees et l'hypertension intracrânienne ont constitue le motif de consultation et le signe d'examen le plus frequent, suivies des signes de focalisation. Les tumeurs supratentorielles ont ete le siege le plus frequemment rencontre (54,38% contre 33,33% de lesions infratentorielles), avec une predominance de lesions gliales notamment l'astrocytome. Une hydrocephalie etait retrouvee dans 31,58% des cas. 70% des patients ont beneficie d'un traitement chirurgical, permettant dans seulement la moitie des cas, soit 38,6%, d'avoir le diagnostic histologique. 15,8% ont beneficie d'une chimiotherapie et un patient d'une radiotherapie. Le taux de mortalite etait de 22,80%. Conclusion Cette etude montre l'interet d'une etude prospective et multicentrique et la necessite de l'amelioration du plateau technique, pour un meilleur diagnostic neuropathologique et une meilleure prise en charge. Background Brains tumors are the most common paediatrics solid tumors, but their incidence is unknowed in subsaharian. Objective To determine the frequency and the distribution of these tumors and to review their management in order to improve their prognosis Materials and methods A retrospective study was done in Abidjan service of neurosurgery of the University Hospital from January 1995 to December 2006, concerning childrens up to the age of 15 years, whose were admitted for brain tumor and diagnosed by CT-scan. Epidemiologicals, clinicals, CT-scan, histopathologicals datas and methods of management were analysed. Results Paediatrics brain tumors (57 cases) have represented 15,74% of all brain tumors (362 cases). The male-female ratio was 1/2 (18 boys and 27 girls ) and the mean age was 8,5 years. The delay of diagnosis was 289 days. Headache and intracranial hypertension were the most common symptoms. 54,38% of brain tumors were located in supratentorial region and 33,33% in the infraten
儿童脑瘤是最常见的儿童实体瘤，但其发病率在撒哈拉以南非洲地区尚不清楚，那里存在诊断和监测延迟的问题。目的评估这些肿瘤的发生率和分布，并提出治疗的特点，以改善预后。材料和方法1995年1月至2006年12月在神经外科进行的回顾性研究，包括年龄在0 - 15岁之间的因脑瘤住院的患者。a扫描仪是术前诊断的唯一手段。对每个患者的流行病学、临床和临床旁特征以及治疗方法进行了分析。结果儿童脑肿瘤(57例)占所有脑肿瘤(362例)的15.74%，性别比例为1/2(18男27女)，平均年龄8.5岁。治疗时间平均为289天。头足类和颅内高血压是会诊的主要原因和最常见的检查迹象，其次是集中症状。幕上肿瘤是最常见的病变(54.38%对33.33%的幕下病变)，以胶质细胞病变为主，特别是星形细胞瘤。31.58%的病例出现脑积水。70%的患者受益于手术治疗，只有一半(38.6%)的病例有组织学诊断。15.8%的患者接受化疗，1名患者接受放疗。死亡率为22.80%。结论本研究表明了前瞻性多中心研究的兴趣和改进技术平台的必要性，以更好的神经病理诊断和更好的护理。背景脑肿瘤是最常见的实体肿瘤，但其发生率在撒哈拉以南非洲地区尚不清楚。客观To the仪器and the成型配送of these tumors and To review their management in order To改进their prognosisMaterials and方法》回顾了study was in service of neurosurgery阿比让爱of the University Hospital)于1995年1月至2006年12月,文化部以及childrens up To the age of 15 years,不要赞美她for brain瘤and diagnosed by CT-scan。对流行病学、临床、ct扫描、组织病理学数据和管理方法进行了分析。结果:脑肿瘤(57例)占所有脑肿瘤(362例)的15.74%。男女比例为1/2(18男27女)，平均年龄为8.5岁。= =地理= =根据美国人口普查局的数据，该县总面积为，其中土地和(1.1%)水。= =地理= =根据美国人口普查，该镇总面积为，其中土地和(1.7%)水。= =地理= =根据美国人口普查局的数据，该县总面积为，其中土地和(1.2%)水。70%的儿童接受了手术治疗，其中一半(38.6%)发现了组织病理学诊断。= =地理= =根据美国人口普查局的数据，该县总面积为，其中土地和(1.0%)水。结论:必须进行前瞻性多中心研究。科室的设备对于改善儿童脑瘤的诊断和治疗是必要的。儿童脑瘤是最常见的儿童实体瘤，但其发病率在撒哈拉以南非洲地区尚不清楚，那里存在诊断和监测延迟的问题。目的评估这些肿瘤的发生率和分布，并提出治疗的特点，以改善预后。材料和方法1995年1月至2006年12月在神经外科进行的回顾性研究，包括年龄在0 - 15岁之间的因脑瘤住院的患者。a扫描仪是术前诊断的唯一手段。对每个患者的流行病学、临床和临床旁特征以及治疗方法进行了分析。结果儿童脑肿瘤(57例)占所有脑肿瘤(362例)的15.74%，性别比例为1/2(18男27女)，平均年龄8.5岁。治疗时间平均为289天。头足类和颅内高血压是会诊的主要原因和最常见的检查迹象，其次是集中症状。幕上肿瘤是最常见的病变(54.38%对33.33%的幕下病变)，以胶质细胞病变为主，特别是星形细胞瘤。31.58%的病例出现脑积水。70%的患者受益于手术治疗，只有一半(38.6%)的病例有组织学诊断。 15.8%的患者接受化疗，1名患者接受放疗。死亡率为22.80%。结论本研究表明了前瞻性多中心研究的兴趣和改进技术平台的必要性，以更好的神经病理诊断和更好的护理。关键词:非洲，脑瘤，儿童，象牙海岸非洲神经科学杂志第26卷(2)2007:27-38页
{"title":"Approche Diagnostique Des Tumeurs Cerebrales Chez L'enfant - Experience Du Service De Neurochirurgie Du Chu De Yopougon Abidjan","authors":"E. Broalet, A. Haidara, Y. Zunon-Kipré, D. N. Oka, H. N'Da, A. Jibia, M. Kakou, G. Varlet, V. Bazeze","doi":"10.4314/AJNS.V26I2.7596","DOIUrl":"https://doi.org/10.4314/AJNS.V26I2.7596","url":null,"abstract":"Introduction \u0000Les tumeurs cerebrales de l'enfant representent les tumeurs solides pediatriques les plus frequentes, mais leur incidence reste meconnue en Afrique subsaharienne ou se pose un probleme de retard diagnostique et de suivi.\u0000\u0000Objectif \u0000Evaluer l'incidence et la distribution de ces tumeurs et presenter les particularites de prise en charge afin d'ameliorer leur pronostic.\u0000\u0000Materiels et methodes \u0000Etude retrospective effectuee dans le service de Neurochirurgie de janvier 1995 a decembre 2006 incluant les patients hospitalises pour une tumeur cerebrale et dont l'âge variait entre 0 et 15 ans revolus. Le scanner a constitue le seul moyen de diagnostic pre-operatoire. Pour chaque patient, les caracteristiques epidemiologiques, cliniques, paracliniques et les modalites de prise en charge ont ete analysees.\u0000\u0000Resultats \u0000Les tumeurs cerebrales de l'enfant (57 cas) representaient 15,74% de toutes les tumeurs cerebrales (362 cas) avec un sex-ratio de 1/2 (18 garcons et 27 filles) et un âge moyen de 8 ans et demi. Le delai de prise en charge a ete de 289 jours en moyenne. Les cephalees et l'hypertension intracrânienne ont constitue le motif de consultation et le signe d'examen le plus frequent, suivies des signes de focalisation. Les tumeurs supratentorielles ont ete le siege le plus frequemment rencontre (54,38% contre 33,33% de lesions infratentorielles), avec une predominance de lesions gliales notamment l'astrocytome. Une hydrocephalie etait retrouvee dans 31,58% des cas. 70% des patients ont beneficie d'un traitement chirurgical, permettant dans seulement la moitie des cas, soit 38,6%, d'avoir le diagnostic histologique. 15,8% ont beneficie d'une chimiotherapie et un patient d'une radiotherapie. Le taux de mortalite etait de 22,80%.\u0000\u0000Conclusion \u0000Cette etude montre l'interet d'une etude prospective et multicentrique et la necessite de l'amelioration du plateau technique, pour un meilleur diagnostic neuropathologique et une meilleure prise en charge.\u0000\u0000 Background \u0000Brains tumors are the most common paediatrics solid tumors, but their incidence is unknowed in subsaharian.\u0000\u0000Objective \u0000To determine the frequency and the distribution of these tumors and to review their management in order to improve their prognosis\u0000\u0000Materials and methods \u0000A retrospective study was done in Abidjan service of neurosurgery of the University Hospital from January 1995 to December 2006, concerning childrens up to the age of 15 years, whose were admitted for brain tumor and diagnosed by CT-scan. Epidemiologicals, clinicals, CT-scan, histopathologicals datas and methods of management were analysed.\u0000\u0000Results \u0000Paediatrics brain tumors (57 cases) have represented 15,74% of all brain tumors (362 cases). The male-female ratio was 1/2 (18 boys and 27 girls ) and the mean age was 8,5 years. The delay of diagnosis was 289 days. Headache and intracranial hypertension were the most common symptoms. 54,38% of brain tumors were located in supratentorial region and 33,33% in the infraten","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"28 6 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2008-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70466511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Komolafe, E. Komolafe, F. Fatoye, V. Adetiloye, C. Asaleye, O. Famurewa, S. Mosaku, Y. Amusa
Background and purpose Stroke is a leading cause of death and neurological disability in adults, and imposes a heavy emotional and financial burden on the family and society. We carried out this study to describe the epidemiological pattern of stroke at the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife and also to describe the risk factors, the computerized tomography (CT) scan findings and the outcome of stroke in our practice setting. Methods We prospectively studied one hundred and thirty five consecutive patients presenting to the neurology unit of the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife over a six year period (2000- 2005). The socio-demographic and clinical data as well as the CT scan findings were collected. Statistical analysis was done using SPSS version 11.0. Results The 135 patients comprised 76 male and 59 female with a mean age of 62+ 12years. The major risk factors were hypertension and diabetes mellitus. Cerebral infarction was the most common subtype of stroke seen. The case fatality rate was 15.6% and among the survivors the outcome was poor as only 3% made full recovery. Conclusion Stroke is still a major problem and the major predisposing factor remains uncontrolled hypertension. The case fatality was very high and there is a risk of moderate to severe neurological disability among the survivors. The utilization of CT scan is sub-optimal even when it is available because of financial constraints. CT scan is recommended for all cases of stroke for definitive diagnosis and timely as well as accurate management. Introduction Les accidents vasculaires cerebraux (AVC) causent une mortalite et un handicap importants dans la population adulte entrainant egalement une forte charge emotionnelle au sein des familles et de la population. Objectifs Nous avons mene une epidemiologique sur la configuration des AVC a l'universite Obafemi Awolowo Teaching Hospitals Complex, Ile-Ife Methodes Nous avons etudie cent trente-cinq patients de maniere consecutive a l'universite Obafemi Awolowo Teaching Hospitals Complex, Ile-Ife, sur une periode de six ans (2000-2005). Les donnees socio-demographiques ainsi que celles du CT-scan ont ete recueillies. L'analyse statistique a ete realisee a l'aide du SPSS version 11.0 Resultats Parmi les 135 patients, 76 etaient de sexe masculin et 59 de sexe feminin avec une moyenne d'âge de 62+12 ans.Les facteurs de risque predominant etaient l'hypertension arterielle (HTA) et le diabete. L'infarcissement cerebral etait observe le plus frequemment. Le taux de mortalite etait de 15.6% et parmi les survivants seuls 3% avaient eu une recuperation complete. Conclusions Les AVC restent un probleme majeur de sante en rapport avec un mauvais controle de l'HTA. Le taux de mortalite est tres eleve et la morbidite variable. Le CT-scan est sous utilise compte tenu des contraintes financieres. Son utilisation devrait etre la regle Keywords : Stroke, Clinical profile, c
背景和目的中风是成人死亡和神经功能障碍的主要原因，给家庭和社会带来沉重的情感和经济负担。我们进行这项研究是为了描述在Ile-Ife的Obafemi Awolowo大学教学医院的中风流行病学模式，并描述在我们的实践环境中中风的危险因素、计算机断层扫描(CT)结果和结果。方法我们前瞻性研究了连续6年(2000- 2005年)在Ile-Ife的Obafemi Awolowo大学教学医院神经内科就诊的135例患者。收集社会人口学、临床资料及CT扫描结果。采用SPSS 11.0进行统计分析。结果135例患者中，男性76例，女性59例，平均年龄62+ 12岁。主要危险因素为高血压和糖尿病。脑梗死是最常见的脑卒中亚型。病死率为15.6%，幸存者的预后很差，只有3%的人完全康复。结论脑卒中仍是主要问题，高血压未控制仍是主要诱因。病死率非常高，幸存者中存在中度至重度神经功能障碍的风险。由于财政限制，即使可以使用CT扫描，其利用率也不是最佳的。CT扫描推荐所有病例中风明确诊断和及时准确的管理。摘要脑血管病(AVC)是一种致命的疾病，是一种重要的疾病，是一种重要的疾病，是一种严重的疾病，是一种严重的疾病，是一种严重的疾病。目的对法国奥巴菲米·阿沃洛沃大学教学医院(Ile-Ife)连续6年(2000-2005年)在法国奥巴菲米·阿沃洛沃大学教学医院(Ile-Ife)连续6年的患者进行调查研究。未完成的社会人口学特征和ct扫描的细胞特征并不常见。结果:本组患者135例，男性76例，女性59例，男性62例+女性12例，高血压小动脉(HTA)和糖尿病为主要危险因素。脑梗死灶观察到低加频率。死亡率为15.6%，存活者中有3%的人需要完全恢复。结论在对肝细胞癌的控制过程中，肝细胞癌不存在重大的健康问题。Le taux de morbidite est treres eleve et la morbidite variable。ct扫描测试可以利用完整的神经系统来控制财务状况。关键词:中风，临床特征，计算机断层扫描，尼日利亚非洲神经科学杂志Vol. 26 (1) 2007: pp. 5-13
{"title":"Profile Of Stroke In Nigerians: A Prospective Clinical Study","authors":"M. Komolafe, E. Komolafe, F. Fatoye, V. Adetiloye, C. Asaleye, O. Famurewa, S. Mosaku, Y. Amusa","doi":"10.4314/AJNS.V26I1.7588","DOIUrl":"https://doi.org/10.4314/AJNS.V26I1.7588","url":null,"abstract":"Background and purpose \u0000Stroke is a leading cause of death and neurological disability in adults, and imposes a heavy emotional and financial burden on the family and society. We carried out this study to describe the epidemiological pattern of stroke at the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife and also to describe the risk factors, the computerized tomography (CT) scan findings and the outcome of stroke in our practice setting.\u0000\u0000Methods \u0000We prospectively studied one hundred and thirty five consecutive patients presenting to the neurology unit of the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife over a six year period (2000- 2005). The socio-demographic and clinical data as well as the CT scan findings were collected. Statistical analysis was done using SPSS version 11.0.\u0000\u0000Results \u0000The 135 patients comprised 76 male and 59 female with a mean age of 62+ 12years. The major risk factors were hypertension and diabetes mellitus. Cerebral infarction was the most common subtype of stroke seen. The case fatality rate was 15.6% and among the survivors the outcome was poor as only 3% made full recovery.\u0000\u0000Conclusion \u0000Stroke is still a major problem and the major predisposing factor remains uncontrolled hypertension. The case fatality was very high and there is a risk of moderate to severe neurological disability among the survivors. The utilization of CT scan is sub-optimal even when it is available because of financial constraints. CT scan is recommended for all cases of stroke for definitive diagnosis and timely as well as accurate management.\u0000\u0000 Introduction \u0000Les accidents vasculaires cerebraux (AVC) causent une mortalite et un handicap importants dans la population adulte entrainant egalement une forte charge emotionnelle au sein des familles et de la population.\u0000\u0000Objectifs \u0000Nous avons mene une epidemiologique sur la configuration des AVC a l'universite Obafemi Awolowo Teaching Hospitals Complex, Ile-Ife\u0000\u0000Methodes \u0000Nous avons etudie cent trente-cinq patients de maniere consecutive a l'universite Obafemi Awolowo Teaching Hospitals Complex, Ile-Ife, sur une periode de six ans (2000-2005). Les donnees socio-demographiques ainsi que celles du CT-scan ont ete recueillies. L'analyse statistique a ete realisee a l'aide du SPSS version 11.0\u0000\u0000Resultats \u0000Parmi les 135 patients, 76 etaient de sexe masculin et 59 de sexe feminin avec une moyenne d'âge de 62+12 ans.Les facteurs de risque predominant etaient l'hypertension arterielle (HTA) et le diabete. L'infarcissement cerebral etait observe le plus frequemment. Le taux de mortalite etait de 15.6% et parmi les survivants seuls 3% avaient eu une recuperation complete.\u0000\u0000Conclusions \u0000Les AVC restent un probleme majeur de sante en rapport avec un mauvais controle de l'HTA. Le taux de mortalite est tres eleve et la morbidite variable. Le CT-scan est sous utilise compte tenu des contraintes financieres. Son utilisation devrait etre la regle\u0000 Keywords : Stroke, Clinical profile, c","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"26 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2008-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Balogou, K. Volley, M. Belo, Amouzou Mk, K. Apetsé, D. Kombate, E. Grunitzky
Description On estime a 2,3 millions, le nombre de personnes decedees du SIDA en 2004 en Afrique subsaharienne. Ainsi le VIH/SIDA a reduit de plus de 20 ans, l'esperance de vie de la population en Afrique. Objectifs Le but de notre etude etait d'identifier les causes de deces et d'etudier la letalite des affections neurologiques chez les personnes vivant avec le VIH/SIDA (PVVIH/SIDA) au CHU-CAMPUS de Lome. Methodes Une etude retrospective transversale avait ete menee sur les dossiers des malades hospitalises dans ledit service du 1er Janvier 1996 au 31 decembre 2005. Resultats Sur les 380 patients seropositifs au VIH enregistres, 83,2 % ne connaissaient pas leur statut serologique a l'admission. L'âge moyen de nos patients decedes etait de 38,9 ± 13,4 ans, avec une duree de sejour moyen avant le deces de 13,9 jours. L'abces cerebral toxoplasmique avait constitue la premiere cause de deces chez les PVVIH/SIDA (40,8 %), suivie des meningites (27,2 %) et des meningo-encephalites (19,0 %). Le taux global de letalite etait de 38,7 %. Les meningites et les meningo-encephalites constituaient les affections les plus letales avec un taux de letalite respectivement de 90,9 % et 70,0 %. Conclusions Les principales affections neurologiques associees a l'infection VIH devraient beneficier d'un diagnostic rapide et de la mise en place de protocole de prise en charge immediate. Des efforts supplementaires doivent etre fournis dans le depistage et la prise en charge des PV VIH /SIDA. Description HIV/AIDS is responsible of about 2,3 billions deaths in subsaharian Africa in 2004. The life expectancy had declined, in this part of continent, of 20 years. Objectives To identify neurological death causes and to study their lethality among HIV positive patients, in Campus Teaching Hospital at Lome. Methods We did a transversal retrospective study on hospitalized patients from January 1, 1996 to December 31, 2005. known their HIV status before their admission. The average age of dead patients was 38,9 ± 13,4 years. Average hospitalization life stay was 13,9 days before death. Cerebral toxoplasmosis abscess was the first cause of death of HIV positive patients (40,8 %), followed by meningitis (27,2 %) and by meningo-encephalitis (19 %). The lethality global rate was 38,7 %. Meningitis and meningo-encephalitis were most lethal diseases, with lethality rate of respectively 90,9 % and 70,0 %. Conclusion Mains neurological diseases associated with HIV infection must be diagnosed quickly and taken in charge without delay. This study has shown that efforts have to be performed in the framework of HIV detection Keywords : HIV/AIDS positive, neurological affections, Togo. African Journal of Neurological Sciences Vol. 26 (2) 2007: pp. 95-101
2004年，撒哈拉以南非洲地区估计有230万人死于艾滋病。因此，艾滋病毒/艾滋病使非洲人口的预期寿命缩短了20多年。目的我们研究的目的是确定死亡的原因，并研究洛美CHU-CAMPUS的hiv / aids (plhiv / aids)患者神经系统疾病的致盲程度。方法对1996年1月1日至2005年12月31日在该病房住院的患者进行回顾性横断面研究。结果380例登记hiv阳性患者中，83.2%在入院时不知道自己的血清学状况。我们的decedes患者平均年龄为38.9±13.4岁，死亡前平均住院时间为13.9天。弓形虫脑脓肿是hiv / aids患者死亡的主要原因(40.8%)，其次是脑膜炎(27.2%)和脑膜炎脑炎(19.0%)。总体letalite率为38.7%。脑膜炎和脑膜炎脑炎是最致命的疾病，致死率分别为90.9%和70.0%。结论与艾滋病毒感染相关的主要神经系统疾病应受益于快速诊断和实施即时护理方案。需要进一步努力查明和管理艾滋病毒/艾滋病PV。2004年，艾滋病毒/艾滋病造成撒哈拉以南非洲约23亿人死亡。生活期望已经下降，在大陆的这一部分，20年。目的是在洛美的校园教学医院查明神经死亡原因并研究艾滋病毒阳性患者的死亡率。方法对1996年1月1日至2005年12月31日住院患者进行横断面回顾性研究。在入院前了解他们的艾滋病毒状况。死亡患者的平均年龄为38.9±13.4岁。平均住院时间为死亡前13.9天。脑弓形虫脓肿是HIV阳性患者死亡的主要原因(40.8%)，其次是脑膜炎(27.2%)和脑膜炎脑炎(19%)。总体死亡率为38.7%。脑膜炎和脑膜炎脑炎是最致命的疾病，致死率分别为90.9%和70.0%。结论必须迅速诊断与艾滋病毒感染有关的手部神经系统疾病，并立即采取行动。这项研究表明，必须在艾滋病毒检测框架内作出努力，关键词:艾滋病毒/艾滋病阳性，神经系统疾病，多哥。非洲神经科学杂志第26卷(2)2007:95-101页
{"title":"Mortalité Des Patients Vih Positifs Dans Le Service De Neurologie Du Chu Campus De Lomé-Togo","authors":"A. Balogou, K. Volley, M. Belo, Amouzou Mk, K. Apetsé, D. Kombate, E. Grunitzky","doi":"10.4314/AJNS.V26I1.7591","DOIUrl":"https://doi.org/10.4314/AJNS.V26I1.7591","url":null,"abstract":"Description \u0000On estime a 2,3 millions, le nombre de personnes decedees du SIDA en 2004 en Afrique subsaharienne. Ainsi le VIH/SIDA a reduit de plus de 20 ans, l'esperance de vie de la population en Afrique.\u0000\u0000Objectifs \u0000Le but de notre etude etait d'identifier les causes de deces et d'etudier la letalite des affections neurologiques chez les personnes vivant avec le VIH/SIDA (PVVIH/SIDA) au CHU-CAMPUS de Lome.\u0000\u0000Methodes \u0000Une etude retrospective transversale avait ete menee sur les dossiers des malades hospitalises dans ledit service du 1er Janvier 1996 au 31 decembre 2005.\u0000\u0000Resultats \u0000Sur les 380 patients seropositifs au VIH enregistres, 83,2 % ne connaissaient pas leur statut serologique a l'admission. L'âge moyen de nos patients decedes etait de 38,9 ± 13,4 ans, avec une duree de sejour moyen avant le deces de 13,9 jours. L'abces cerebral toxoplasmique avait constitue la premiere cause de deces chez les PVVIH/SIDA (40,8 %), suivie des meningites (27,2 %) et des meningo-encephalites (19,0 %). Le taux global de letalite etait de 38,7 %. Les meningites et les meningo-encephalites constituaient les affections les plus letales avec un taux de letalite respectivement de 90,9 % et 70,0 %.\u0000\u0000Conclusions \u0000Les principales affections neurologiques associees a l'infection VIH devraient beneficier d'un diagnostic rapide et de la mise en place de protocole de prise en charge immediate. Des efforts supplementaires doivent etre fournis dans le depistage et la prise en charge des PV VIH /SIDA.\u0000\u0000 Description \u0000HIV/AIDS is responsible of about 2,3 billions deaths in subsaharian Africa in 2004. The life expectancy had declined, in this part of continent, of 20 years.\u0000\u0000Objectives \u0000To identify neurological death causes and to study their lethality among HIV positive patients, in Campus Teaching Hospital at Lome.\u0000\u0000Methods \u0000We did a transversal retrospective study on hospitalized patients from January 1, 1996 to December 31, 2005. known their HIV status before their admission. The average age of dead patients was 38,9 ± 13,4 years. Average hospitalization life stay was 13,9 days before death. Cerebral toxoplasmosis abscess was the first cause of death of HIV positive patients (40,8 %), followed by meningitis (27,2 %) and by meningo-encephalitis (19 %). The lethality global rate was 38,7 %. Meningitis and meningo-encephalitis were most lethal diseases, with lethality rate of respectively 90,9 % and 70,0 %.\u0000\u0000Conclusion \u0000Mains neurological diseases associated with HIV infection must be diagnosed quickly and taken in charge without delay. This study has shown that efforts have to be performed in the framework of HIV detection\u0000 Keywords : HIV/AIDS positive, neurological affections, Togo. African Journal of Neurological Sciences Vol. 26 (2) 2007: pp. 95-101","PeriodicalId":42149,"journal":{"name":"African Journal of Neurological Sciences","volume":"26 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2008-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70465875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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