Pub Date : 2020-07-01DOI: 10.4103/ijdpdd.ijdpdd_46_20
Y. Bhat, Nahida Nabi, Rohi Wani
{"title":"Dermoscopy of disseminated superficial actinic porokeratosis in skin of color","authors":"Y. Bhat, Nahida Nabi, Rohi Wani","doi":"10.4103/ijdpdd.ijdpdd_46_20","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_46_20","url":null,"abstract":"","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124815786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-01DOI: 10.4103/ijdpdd.ijdpdd_54_20
B. Warpe, Bhagyashree S. Mundhe, Shweta Joshi-Warpe, Ashwin Kulkarni
Tuberous sclerosis complex (TSC) or Bourneville's disease is a genetic multisystem disorder of multisite hamartomas. Majority of TSC cases are sporadic. TSC typically presents in the first decade of life and has a reported incidence of 1:6000–12,000, with intracranial involvement in the form of cortical tubers or subependymal nodules. Tubers (potato-like nodules) are triangular-shaped lesions centered at the cortex/juxtacortical, with apex oriented “inward” toward the ventricles, on magnetic resonance imaging (MRI) of the brain. Tubers represent cortical glioneuronal hamartomas and consist of focal distortions in the cellular organization and morphology, which extend into the underlying (subcortical) white matter. Skin lesions with a history of seizures can be an eye-opener to diagnose angiofibromas and its variant, which can lead to further effective workup such as ophthalmoscopy and MRI of the brain to diagnose TSC, just like in our case.
{"title":"Cutaneous angiofibroma: A clinching evidence for diagnostic workup of tuberous sclerosis complex","authors":"B. Warpe, Bhagyashree S. Mundhe, Shweta Joshi-Warpe, Ashwin Kulkarni","doi":"10.4103/ijdpdd.ijdpdd_54_20","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_54_20","url":null,"abstract":"Tuberous sclerosis complex (TSC) or Bourneville's disease is a genetic multisystem disorder of multisite hamartomas. Majority of TSC cases are sporadic. TSC typically presents in the first decade of life and has a reported incidence of 1:6000–12,000, with intracranial involvement in the form of cortical tubers or subependymal nodules. Tubers (potato-like nodules) are triangular-shaped lesions centered at the cortex/juxtacortical, with apex oriented “inward” toward the ventricles, on magnetic resonance imaging (MRI) of the brain. Tubers represent cortical glioneuronal hamartomas and consist of focal distortions in the cellular organization and morphology, which extend into the underlying (subcortical) white matter. Skin lesions with a history of seizures can be an eye-opener to diagnose angiofibromas and its variant, which can lead to further effective workup such as ophthalmoscopy and MRI of the brain to diagnose TSC, just like in our case.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121498913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-01DOI: 10.4103/ijdpdd.ijdpdd_18_20
Anuja Sunkwad, S. Mahajan, J. Dave, D. Das
Brooke–Spiegler syndrome (BSS) is a rare autosomal dominant inherited disorder characterized by multiple skin appendageal tumors. The predominant tumors can be a cylindroma, trichoepithelioma, and/or spiradenoma. Here we report this rare entity of Brooke–Spiegler syndrome in a 50 year old female on the basis of clinico-histopathological correlation. The gene responsible for this condition is cylindromatosis gene (CYLD1) which has been mapped on chromosome 16q12–q13. However, no mutation have been detected in CYLD gene analyzed in our patient which indicates lack of genotype–phenotype correlation in this patient.
{"title":"A rare case of Brooke–Spiegler syndrome","authors":"Anuja Sunkwad, S. Mahajan, J. Dave, D. Das","doi":"10.4103/ijdpdd.ijdpdd_18_20","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_18_20","url":null,"abstract":"Brooke–Spiegler syndrome (BSS) is a rare autosomal dominant inherited disorder characterized by multiple skin appendageal tumors. The predominant tumors can be a cylindroma, trichoepithelioma, and/or spiradenoma. Here we report this rare entity of Brooke–Spiegler syndrome in a 50 year old female on the basis of clinico-histopathological correlation. The gene responsible for this condition is cylindromatosis gene (CYLD1) which has been mapped on chromosome 16q12–q13. However, no mutation have been detected in CYLD gene analyzed in our patient which indicates lack of genotype–phenotype correlation in this patient.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127614518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-01DOI: 10.4103/ijdpdd.ijdpdd_96_20
P. Kowe, S. Malpani, V. Wankhade, R. Singh
Lymphangioma circumscriptum (LC) is a rare benign hamartomatous malformation of lymph vessel manifesting at birth or during early childhood. Angiokeratomas (AK) are vascular ectasia of papillary dermal blood vessels with secondary epidermal changes. AK and/or LC are one of the common vascular malformations associated with Klippel–Trenaunay syndrome (KTS). The simultaneous appearance of LC and AK has been reported rarely, and the occurrence of LC, AK, and port-wine stain in a patient of KTS is even rarer. Thereby, we report a case of co-occurrence of LC and AK in the same patient without systemic involvement.
{"title":"Zosteriform lymphangioma circumscriptum and angiokeratoma: A rare co-occurrence","authors":"P. Kowe, S. Malpani, V. Wankhade, R. Singh","doi":"10.4103/ijdpdd.ijdpdd_96_20","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_96_20","url":null,"abstract":"Lymphangioma circumscriptum (LC) is a rare benign hamartomatous malformation of lymph vessel manifesting at birth or during early childhood. Angiokeratomas (AK) are vascular ectasia of papillary dermal blood vessels with secondary epidermal changes. AK and/or LC are one of the common vascular malformations associated with Klippel–Trenaunay syndrome (KTS). The simultaneous appearance of LC and AK has been reported rarely, and the occurrence of LC, AK, and port-wine stain in a patient of KTS is even rarer. Thereby, we report a case of co-occurrence of LC and AK in the same patient without systemic involvement.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"158 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116232463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-01DOI: 10.4103/ijdpdd.ijdpdd_48_20
Bhavesh Sonagara, Hita H. Mehta, B. Astik, N. Agrawal
Background: Seborrheic keratosis (SK) is the most common benign skin tumor. Dermatoscope is a simple noninvasive diagnostic tool. Although SK has been well recognized clinically, dermoscopically, and histopathologically, data regarding dermoscopic differentiation of different types of SK using the polarized (P) and nonpolarized (NP) modes of dermoscopy are inadequate. Objectives: The objective was to study the dermoscopic pattern of different types of SK under P and NP dermoscopic modes. Methodology: A descriptive study of 102 patients was carried out after ethical approval. All patients attending the dermatology outpatient department with lesions who were willing to participate in the study were included in the study after taking written informed consent. After a detailed history and examination, clinical and dermoscopic photographs were taken under the P and NP modes of a dermoscope attached with a smartphone camera. Biopsy of the same lesions was sent for a histopathology examination. Results: A total of 102 patients were studied. Females (58) outnumbered males (44). The most common clinical variant was common SK. The most common histopathological type of SK was hyperkeratotic followed by acanthotic type. Sharp demarcated border (75%) was the most common finding on dermoscopy in our study followed by fissure and ridges (63%), scales (54%), comedo-like opening (34%), cobblestone-like pattern (33%), moth-eaten border (17.7%), and cerebriform pattern (13.7%). Conclusion: NP mode helps in better visualization as well as depth perception, whereas P mode shows better color perception and sharpness of superficial as well as deep dermoscopic structures.
{"title":"Study of seborrheic keratosis by dermoscopy using polarized and nonpolarized modes","authors":"Bhavesh Sonagara, Hita H. Mehta, B. Astik, N. Agrawal","doi":"10.4103/ijdpdd.ijdpdd_48_20","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_48_20","url":null,"abstract":"Background: Seborrheic keratosis (SK) is the most common benign skin tumor. Dermatoscope is a simple noninvasive diagnostic tool. Although SK has been well recognized clinically, dermoscopically, and histopathologically, data regarding dermoscopic differentiation of different types of SK using the polarized (P) and nonpolarized (NP) modes of dermoscopy are inadequate. Objectives: The objective was to study the dermoscopic pattern of different types of SK under P and NP dermoscopic modes. Methodology: A descriptive study of 102 patients was carried out after ethical approval. All patients attending the dermatology outpatient department with lesions who were willing to participate in the study were included in the study after taking written informed consent. After a detailed history and examination, clinical and dermoscopic photographs were taken under the P and NP modes of a dermoscope attached with a smartphone camera. Biopsy of the same lesions was sent for a histopathology examination. Results: A total of 102 patients were studied. Females (58) outnumbered males (44). The most common clinical variant was common SK. The most common histopathological type of SK was hyperkeratotic followed by acanthotic type. Sharp demarcated border (75%) was the most common finding on dermoscopy in our study followed by fissure and ridges (63%), scales (54%), comedo-like opening (34%), cobblestone-like pattern (33%), moth-eaten border (17.7%), and cerebriform pattern (13.7%). Conclusion: NP mode helps in better visualization as well as depth perception, whereas P mode shows better color perception and sharpness of superficial as well as deep dermoscopic structures.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128848811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.4103/ijdpdd.ijdpdd_36_20
Molisha Bhandari, G. Khullar, Shruti Sharma, V. Ramesh
{"title":"Curious case of coexistence of erythema induratum and penile papulonecrotic tuberculid","authors":"Molisha Bhandari, G. Khullar, Shruti Sharma, V. Ramesh","doi":"10.4103/ijdpdd.ijdpdd_36_20","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_36_20","url":null,"abstract":"","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"455 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123639518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.4103/ijdpdd.ijdpdd_12_19
Nilima Sharma, M. Hassan
Benign fibrous histiocytomas of soft tissue are composed of spindled fibroblasts admixed with secondary elements including histiocytes, foam cells, and inflammatory cells. These tumors occur equally in males and females and most often arise in the dermis and subcutaneous tissues. We report a rare case of benign fibrous histiocytic tumor of the palate with histologic features and immunohistochemical characteristics.
{"title":"Benign fibrohistiocytic tumour of the palate","authors":"Nilima Sharma, M. Hassan","doi":"10.4103/ijdpdd.ijdpdd_12_19","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_12_19","url":null,"abstract":"Benign fibrous histiocytomas of soft tissue are composed of spindled fibroblasts admixed with secondary elements including histiocytes, foam cells, and inflammatory cells. These tumors occur equally in males and females and most often arise in the dermis and subcutaneous tissues. We report a rare case of benign fibrous histiocytic tumor of the palate with histologic features and immunohistochemical characteristics.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114718237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.4103/ijdpdd.ijdpdd_44_19
Gurpinder Kaur, R. Punia, R. Kundu, G. Thami
Background: Vitiligo is the most prevalent pigmentary disorder occurring worldwide. In most cases, the diagnosis is made by clinical examination alone. The disease status (active/stable) needs to be assessed to make appropriate therapeutic decisions. Objective: The aim of the present study was to evaluate the histopathological and immunohistochemical features in active and stable lesions. Materials and Methods: Biopsies from vitiliginous areas from 50 patients (25 each of clinically active and stable vitiligo); with hematoxylin and eosin, Masson Fontana (MF), S-100, and human melanoma black-45 (HMB-45) stained sections were studied. Results: Age of the patients ranged from 7 to 69 years (mean age: 33.6 ± 15.73 years). Of 50 patients, 27 (54%) were male and 23 (46%) were female. All the cases showed variable degree of basal hypopigmentation. Histopathological findings, epidermal spongiosis, basal vacuolar degeneration, dermal melanophages, and dermal lymphomononuclear cells were commonly observed in active lesions as compared to the stable ones. On MF staining, 23/25 cases (92%) of active vitiligo showed complete loss of basal melanin. Quantitative analysis of HMB-45 immunostaining in stable and active vitiligo revealed mean number of positive melanocytes as 2.52 ± 1.0/high power field (hpf) and 0.08 ± 0.28/hpf, respectively, while on S-100 immunostaining the mean values of positive Langerhans cells were 1.70 ± 0.38/hpf and 7.78 ± 4.11/hpf, respectively. Conclusion: The demonstration of overall reduction in the number of HMB-45-positive melanocytes and increase in S-100-positive Langerhans dendritic cells in the active vitiligo lesions is facilitated by immunohistochemistry. The technique is of immense help in differentiating active and stable stages of vitiligo, thus guiding therapy.
{"title":"Evaluation of active and stable stages of vitiligo using S-100 and human melanoma black-45 immunostains","authors":"Gurpinder Kaur, R. Punia, R. Kundu, G. Thami","doi":"10.4103/ijdpdd.ijdpdd_44_19","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_44_19","url":null,"abstract":"Background: Vitiligo is the most prevalent pigmentary disorder occurring worldwide. In most cases, the diagnosis is made by clinical examination alone. The disease status (active/stable) needs to be assessed to make appropriate therapeutic decisions. Objective: The aim of the present study was to evaluate the histopathological and immunohistochemical features in active and stable lesions. Materials and Methods: Biopsies from vitiliginous areas from 50 patients (25 each of clinically active and stable vitiligo); with hematoxylin and eosin, Masson Fontana (MF), S-100, and human melanoma black-45 (HMB-45) stained sections were studied. Results: Age of the patients ranged from 7 to 69 years (mean age: 33.6 ± 15.73 years). Of 50 patients, 27 (54%) were male and 23 (46%) were female. All the cases showed variable degree of basal hypopigmentation. Histopathological findings, epidermal spongiosis, basal vacuolar degeneration, dermal melanophages, and dermal lymphomononuclear cells were commonly observed in active lesions as compared to the stable ones. On MF staining, 23/25 cases (92%) of active vitiligo showed complete loss of basal melanin. Quantitative analysis of HMB-45 immunostaining in stable and active vitiligo revealed mean number of positive melanocytes as 2.52 ± 1.0/high power field (hpf) and 0.08 ± 0.28/hpf, respectively, while on S-100 immunostaining the mean values of positive Langerhans cells were 1.70 ± 0.38/hpf and 7.78 ± 4.11/hpf, respectively. Conclusion: The demonstration of overall reduction in the number of HMB-45-positive melanocytes and increase in S-100-positive Langerhans dendritic cells in the active vitiligo lesions is facilitated by immunohistochemistry. The technique is of immense help in differentiating active and stable stages of vitiligo, thus guiding therapy.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116765570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.4103/ijdpdd.ijdpdd_44_20
C. Desai, Saurabh Shah
{"title":"Cystic follicular hamartoma: A rare case report","authors":"C. Desai, Saurabh Shah","doi":"10.4103/ijdpdd.ijdpdd_44_20","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_44_20","url":null,"abstract":"","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116498822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.4103/ijdpdd.ijdpdd_59_19
L. Mohamed, E. Hasby, H. Kassem, Nashwa N Elfar
Background: Wnt genes code for a family of secreted, lipid-modified glycoproteins. Wnt5a has important functions in cell proliferation, fate determination, and differentiation. Dysregulation of Wnt5a signaling implicated in multiple disease. Aim of Work: The aim is to elucidate the possible role of Wnt5a in pathogenesis of papulosquamous skin disorders through the evaluation of its expression immunohistochemically. Patients and Methods: This study included 80 patients with various papulosquamous diseases (psoriasis, lichen planus, ptyriasis rosea, and ptyriasis rubra pilaris), in addition to 20 healthy controls served as control. Punch skin biopsies were taken from all individuals for immunohistochemical staining with Wnt5a. Results: There was a highly statistically significant upregulation in Wnt5a expression in all stained skin specimens of the studied papulosquamous diseases in both epidermis and dermal lymphocytes compared to normal control. Conclusion: The upregulated expression of Wnt5a indicated its involvement in pathogenesis of papulosquamous diseases. Wnt5a and/or its receptor can be a challenging target for therapeutic intervention. Regular follow-up for these patients is recommended as Wnt5a also may be involved in their malignant transformation.
{"title":"A possible role of WNT5A expression in papulosquamous skin diseases","authors":"L. Mohamed, E. Hasby, H. Kassem, Nashwa N Elfar","doi":"10.4103/ijdpdd.ijdpdd_59_19","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_59_19","url":null,"abstract":"Background: Wnt genes code for a family of secreted, lipid-modified glycoproteins. Wnt5a has important functions in cell proliferation, fate determination, and differentiation. Dysregulation of Wnt5a signaling implicated in multiple disease. Aim of Work: The aim is to elucidate the possible role of Wnt5a in pathogenesis of papulosquamous skin disorders through the evaluation of its expression immunohistochemically. Patients and Methods: This study included 80 patients with various papulosquamous diseases (psoriasis, lichen planus, ptyriasis rosea, and ptyriasis rubra pilaris), in addition to 20 healthy controls served as control. Punch skin biopsies were taken from all individuals for immunohistochemical staining with Wnt5a. Results: There was a highly statistically significant upregulation in Wnt5a expression in all stained skin specimens of the studied papulosquamous diseases in both epidermis and dermal lymphocytes compared to normal control. Conclusion: The upregulated expression of Wnt5a indicated its involvement in pathogenesis of papulosquamous diseases. Wnt5a and/or its receptor can be a challenging target for therapeutic intervention. Regular follow-up for these patients is recommended as Wnt5a also may be involved in their malignant transformation.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134173773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}