Pub Date : 2019-07-01DOI: 10.4103/ijdpdd.ijdpdd_40_19
B. Iqbal, P. Khandekar, I. Dey, H. Kumar
Eccrine syringofibroadenoma (ESFA) is a rare adnexal tumor. It was first described by Mascaro in 1963. They are predominantly seen on the extremities of middle aged to elderly patients. Clinically, ESFA is classified into five subtypes. Solitary ESFA, the most common subtype, usually presents as a skin-colored papule, plaque, or nodule. The histomorphological and immunohistochemical features are necessary for their diagnosis and are also required to differentiate them from their malignant counterpart, eccrine syringofibrocarcinoma.
{"title":"Syringofibroadenoma: Benign eccrine sweat gland tumor – A rare case report","authors":"B. Iqbal, P. Khandekar, I. Dey, H. Kumar","doi":"10.4103/ijdpdd.ijdpdd_40_19","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_40_19","url":null,"abstract":"Eccrine syringofibroadenoma (ESFA) is a rare adnexal tumor. It was first described by Mascaro in 1963. They are predominantly seen on the extremities of middle aged to elderly patients. Clinically, ESFA is classified into five subtypes. Solitary ESFA, the most common subtype, usually presents as a skin-colored papule, plaque, or nodule. The histomorphological and immunohistochemical features are necessary for their diagnosis and are also required to differentiate them from their malignant counterpart, eccrine syringofibrocarcinoma.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129003955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-01DOI: 10.4103/ijdpdd.ijdpdd_44_18
Sandhya Chauhan, Anchana Gulati, G. Tegta, M. Gupta
Sir, Histiocytoses are a rare group of disorders resulting from reactive or malignant proliferation of mononuclear phagocyte and immunoregulatory effector system. Generalized eruptive histiocytosis (GEH) is a rare variant of histiocytosis first described by Winkelmann and Muller.[1] There are only approximately 43 case reports of GEH till date.[2] We are reporting a 41-year-old male who was suspected as Hansen’s disease, but clinicopathological correlation confirmed GEH.
{"title":"Clinicopathological correlation in diagnosis of generalized eruptive histiocytosis","authors":"Sandhya Chauhan, Anchana Gulati, G. Tegta, M. Gupta","doi":"10.4103/ijdpdd.ijdpdd_44_18","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_44_18","url":null,"abstract":"Sir, Histiocytoses are a rare group of disorders resulting from reactive or malignant proliferation of mononuclear phagocyte and immunoregulatory effector system. Generalized eruptive histiocytosis (GEH) is a rare variant of histiocytosis first described by Winkelmann and Muller.[1] There are only approximately 43 case reports of GEH till date.[2] We are reporting a 41-year-old male who was suspected as Hansen’s disease, but clinicopathological correlation confirmed GEH.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126538585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-01DOI: 10.4103/ijdpdd.ijdpdd_21_19
P. Garg, P. Balasubramanian
Sir, Bowen’s disease is an intraepidermal squamous cell carcinoma (SCC), also termed as carcinoma in situ. It usually occurs in 6th–8th decades of life, predominantly in the head-and-neck area.[1] It presents as well-defined gradually progressing erythematous patches or plaques with scaly or crusted surface.[2] Early diagnosis and treatment are required as it has the risk of progression to invasive SCC. We herewith report a case of retroauricular Bowen’s disease considering the rarity of the site being involved and to depict the successful therapeutic response to 5-fluorouracil (5-FU) cream.
{"title":"Retroauricular bowen's disease of skin in an elderly female","authors":"P. Garg, P. Balasubramanian","doi":"10.4103/ijdpdd.ijdpdd_21_19","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_21_19","url":null,"abstract":"Sir, Bowen’s disease is an intraepidermal squamous cell carcinoma (SCC), also termed as carcinoma in situ. It usually occurs in 6th–8th decades of life, predominantly in the head-and-neck area.[1] It presents as well-defined gradually progressing erythematous patches or plaques with scaly or crusted surface.[2] Early diagnosis and treatment are required as it has the risk of progression to invasive SCC. We herewith report a case of retroauricular Bowen’s disease considering the rarity of the site being involved and to depict the successful therapeutic response to 5-fluorouracil (5-FU) cream.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130771686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-01DOI: 10.4103/ijdpdd.ijdpdd_33_19
G. Khullar, Niti Khunger, K. Mann, S. Shruti
There has been a rising trend of tattooing in the recent years, resulting in an increased incidence of cutaneous adverse effects. A wide range of infectious and noninfectious dermatoses have been described to occur within tattoos. Cutaneous complications developing in tattooed skin as the initial manifestation of the disease are uncommon. We describe two interesting cases with black tattoo-related reactions as the presenting feature of lepromatous leprosy and cutaneous sarcoidosis, respectively.
{"title":"Tattoo reactions as the initial presentation of lepromatous leprosy and cutaneous sarcoidosis: Report of two cases","authors":"G. Khullar, Niti Khunger, K. Mann, S. Shruti","doi":"10.4103/ijdpdd.ijdpdd_33_19","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_33_19","url":null,"abstract":"There has been a rising trend of tattooing in the recent years, resulting in an increased incidence of cutaneous adverse effects. A wide range of infectious and noninfectious dermatoses have been described to occur within tattoos. Cutaneous complications developing in tattooed skin as the initial manifestation of the disease are uncommon. We describe two interesting cases with black tattoo-related reactions as the presenting feature of lepromatous leprosy and cutaneous sarcoidosis, respectively.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129758503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-01DOI: 10.4103/ijdpdd.ijdpdd_9_19
B. Kumarguru, N. Haripriya, A. Ramaswamy, M. Nirmala
Neurocristic cutaneous hamartoma (NCH) is a rare entity characterized by hamartomatous proliferation of melanocytic, neuroid, and mesenchymal tissues. It results from the aberrant development of the neural crest cells. A 29-year-old female presented with a painless pedunculated swelling over the lower back for 1 year. Grossly, the lesion was skin covered polypoidal tissue. Cut section showed gray-white to gray-yellow areas. Histologically, the lesion was composed of mesenchymal elements and ectodermal elements. Mesenchymal elements were composed of lobules of adipocytes, bundles of smooth muscle tissue, and bone tissue. Ectodermal derivative tissues were composed of nerve bundles and melanocytes. Melanocytes showed a normal maturation pattern. Features were suggestive of a hamartomatous lesion favoring NCH. On immunohistochemistry (IHC), melanocytic cells showed strong positivity for S100. They were also positive for HMB45. Spindle-shaped cells in the connective tissue were positive for CD34. IHC supported the histopathological diagnosis. NCH is a rare entity and poses a diagnostic challenge. IHC may be helpful, but a pathologist has to primarily depend on the histopathological characteristics of the lesion for diagnosing the condition.
{"title":"Neurocristic cutaneous hamartoma: Case report of a rare entity","authors":"B. Kumarguru, N. Haripriya, A. Ramaswamy, M. Nirmala","doi":"10.4103/ijdpdd.ijdpdd_9_19","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_9_19","url":null,"abstract":"Neurocristic cutaneous hamartoma (NCH) is a rare entity characterized by hamartomatous proliferation of melanocytic, neuroid, and mesenchymal tissues. It results from the aberrant development of the neural crest cells. A 29-year-old female presented with a painless pedunculated swelling over the lower back for 1 year. Grossly, the lesion was skin covered polypoidal tissue. Cut section showed gray-white to gray-yellow areas. Histologically, the lesion was composed of mesenchymal elements and ectodermal elements. Mesenchymal elements were composed of lobules of adipocytes, bundles of smooth muscle tissue, and bone tissue. Ectodermal derivative tissues were composed of nerve bundles and melanocytes. Melanocytes showed a normal maturation pattern. Features were suggestive of a hamartomatous lesion favoring NCH. On immunohistochemistry (IHC), melanocytic cells showed strong positivity for S100. They were also positive for HMB45. Spindle-shaped cells in the connective tissue were positive for CD34. IHC supported the histopathological diagnosis. NCH is a rare entity and poses a diagnostic challenge. IHC may be helpful, but a pathologist has to primarily depend on the histopathological characteristics of the lesion for diagnosing the condition.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121209968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-01DOI: 10.4103/ijdpdd.ijdpdd_74_18
Bhavesh Sonagara, Hita H. Mehta, Prachi C Gajjar
Cutaneous amyloidosis refers to a group of skin diseases, which is characterized by the deposition of amyloid material in the skin. Among them, Localized cutaneous nodular amyloidosis (LCNA) is the rarest type of cutaneous amyloidosis. A 38-year-old male presented to dermatology OPD with a single soft nodular lesion on left cheek. On basis of clinical and dermoscopic examination we thought it as granulomatous disease but histopathologically confirmed diagnosis of LCNA. Systemic amyloidosis is excluded on clinical as well as laboratory bases. The patient was treated with topical tacrolimus with slight improvement and followed up for 1 year and no systemic abnormalities were found.
{"title":"Dermoscopy of localized cutaneous nodular amyloidosis resembling granulomatous disorders","authors":"Bhavesh Sonagara, Hita H. Mehta, Prachi C Gajjar","doi":"10.4103/ijdpdd.ijdpdd_74_18","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_74_18","url":null,"abstract":"Cutaneous amyloidosis refers to a group of skin diseases, which is characterized by the deposition of amyloid material in the skin. Among them, Localized cutaneous nodular amyloidosis (LCNA) is the rarest type of cutaneous amyloidosis. A 38-year-old male presented to dermatology OPD with a single soft nodular lesion on left cheek. On basis of clinical and dermoscopic examination we thought it as granulomatous disease but histopathologically confirmed diagnosis of LCNA. Systemic amyloidosis is excluded on clinical as well as laboratory bases. The patient was treated with topical tacrolimus with slight improvement and followed up for 1 year and no systemic abnormalities were found.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126130982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-01DOI: 10.4103/ijdpdd.ijdpdd_53_19
B. Darkase, A. Dongre, P. Choudhary, U. Khopkar
Masson's tumor is a rare, benign, reactive proliferating vascular lesion. The most commonly affected sites are the head, neck, and extremities. We present a 29-year-old male, a case of Masson's tumor over the forehead. Masson's tumor, with the involvement of the forehead is rare and intriguing in this case. Masson's tumor is a benign tumor that may get confused on histopathology with malignant tumors; hence, dermatologists need to understand this entity to avoid unnecessary confusion.
{"title":"Masson's tumor on the forehead: A rare and Benign entity","authors":"B. Darkase, A. Dongre, P. Choudhary, U. Khopkar","doi":"10.4103/ijdpdd.ijdpdd_53_19","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_53_19","url":null,"abstract":"Masson's tumor is a rare, benign, reactive proliferating vascular lesion. The most commonly affected sites are the head, neck, and extremities. We present a 29-year-old male, a case of Masson's tumor over the forehead. Masson's tumor, with the involvement of the forehead is rare and intriguing in this case. Masson's tumor is a benign tumor that may get confused on histopathology with malignant tumors; hence, dermatologists need to understand this entity to avoid unnecessary confusion.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"54 31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131367497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-01DOI: 10.4103/ijdpdd.ijdpdd_27_19
B. Nirmal, A. Krishnaram, R. Sudhagar
Sir, Dermatoscope is considered a vital tool in the diagnosis of basal cell carcinoma (BCC), helping in the early diagnosis and differentiating from other clinical mimics. Dermatoscopy of nodular BCC shows arborizing vessels, ulceration, large blue-gray ovoid nests, and multiple blue-gray globules, whereas superficial BCC shows brown pigmented structures including concentric structures, leaf-like areas, spoke wheel areas, erosions, and superficial fine telangiectasia.[1]
{"title":"Rainbow sign in dermatoscopy of nodular basal cell carcinoma","authors":"B. Nirmal, A. Krishnaram, R. Sudhagar","doi":"10.4103/ijdpdd.ijdpdd_27_19","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_27_19","url":null,"abstract":"Sir, Dermatoscope is considered a vital tool in the diagnosis of basal cell carcinoma (BCC), helping in the early diagnosis and differentiating from other clinical mimics. Dermatoscopy of nodular BCC shows arborizing vessels, ulceration, large blue-gray ovoid nests, and multiple blue-gray globules, whereas superficial BCC shows brown pigmented structures including concentric structures, leaf-like areas, spoke wheel areas, erosions, and superficial fine telangiectasia.[1]","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115127648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-01DOI: 10.4103/ijdpdd.ijdpdd_1_18
Chinmay Kar, R. Biswas, Sabyasachi Banerjee, P. Sarkar, Kaushik Shome, K. Das
Sir, The histiocytoses are the accumulation of reactive or neoplastic histiocytes in various tissues. Among these, non-Langerhans cell histiocytosis (non-LCH) is a broad group of disorders characterized by proliferation of histiocytes other than Langerhans cell. In non-LCH, generalized eruptive histiocytosis (GEH), first described by Winkelmann and Muller, is a rare histiocytic tumor.[1] It is mostly found in adults; childhood GEH accounts for one-fourth of the cases.[2] Here, we report a case of childhood GEH.
{"title":"Generalized eruptive histiocytosis in a child: A rare entity","authors":"Chinmay Kar, R. Biswas, Sabyasachi Banerjee, P. Sarkar, Kaushik Shome, K. Das","doi":"10.4103/ijdpdd.ijdpdd_1_18","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_1_18","url":null,"abstract":"Sir, The histiocytoses are the accumulation of reactive or neoplastic histiocytes in various tissues. Among these, non-Langerhans cell histiocytosis (non-LCH) is a broad group of disorders characterized by proliferation of histiocytes other than Langerhans cell. In non-LCH, generalized eruptive histiocytosis (GEH), first described by Winkelmann and Muller, is a rare histiocytic tumor.[1] It is mostly found in adults; childhood GEH accounts for one-fourth of the cases.[2] Here, we report a case of childhood GEH.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133723906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-01DOI: 10.4103/ijdpdd.ijdpdd_48_18
Inchara K. Yeliur, R. Tirumalae
Alopecia is a common condition that frequently poses a challenge to pathologists and dermatologists alike. Its' classification is still evolving, and there are several areas of overlap. From the therapeutic and prognostic point of view, it is vital to discriminate between scarring and nonscarring alopecia. Histopathology is the most valuable tool in diagnosis. This review attempts to give an overview of hair anatomy and histology and discusses a simple, practical, microscopy-based classification of the commonly encountered diseases. It emphasizes the importance of examining the biopsy under scanning magnification, which is often overlooked and can provide vital clues. Some of the diagnostic challenges are also highlighted.
{"title":"Histopathologic approach to alopecia","authors":"Inchara K. Yeliur, R. Tirumalae","doi":"10.4103/ijdpdd.ijdpdd_48_18","DOIUrl":"https://doi.org/10.4103/ijdpdd.ijdpdd_48_18","url":null,"abstract":"Alopecia is a common condition that frequently poses a challenge to pathologists and dermatologists alike. Its' classification is still evolving, and there are several areas of overlap. From the therapeutic and prognostic point of view, it is vital to discriminate between scarring and nonscarring alopecia. Histopathology is the most valuable tool in diagnosis. This review attempts to give an overview of hair anatomy and histology and discusses a simple, practical, microscopy-based classification of the commonly encountered diseases. It emphasizes the importance of examining the biopsy under scanning magnification, which is often overlooked and can provide vital clues. Some of the diagnostic challenges are also highlighted.","PeriodicalId":423971,"journal":{"name":"Indian Journal of Dermatopathology and Diagnostic Dermatology","volume":"186 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116146018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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