Pub Date : 2018-11-30DOI: 10.14390/JSSHP.HRP2018-005
Hideko Kotani, K. Matsubara, T. Koshizuka, K. Nishiyama, H. Kaneko, Mie Tasaka, Takashi Sugiyama, T. Suzutani
Aim: Vaginal environment is an important factor in predicting threatened abortion and premature rupture of membranes (PROM) in early pregnancy. Vaginal human β -defensin-2 (HBD-2), a main antimicrobial peptide associated with innate immunity, plays multiple roles to protect the lower genital tract from microbes. This study aimed to assess the usefulness of vaginal HBD-2 as a biochemical marker for monitoring the vaginal environment in pregnant women. Methods: Twenty-eight pregnant women were enrolled in this study. Vaginal secretion samples were collected to determine Nugent scores, and vaginal washing fluid (4 ml saline) was used to measure HBD-2 levels by ELISA. Results: In the first trimester, vaginal HBD-2 levels were significantly lower in patients with bacterial vaginosis (BV) (42.1 ± 19.8 pg/ml) compared to those without BV (350.1 ± 68.7 pg/ml, P < 0.05), and in patients with PROM (57.2 ± 31.9
目的:阴道环境是预测早孕先兆流产和胎膜早破的重要因素。阴道人β -防御素-2 (HBD-2)是一种与先天免疫相关的主要抗菌肽，在保护下生殖道免受微生物侵害方面发挥着多种作用。本研究旨在评估阴道HBD-2作为监测孕妇阴道环境的生化标志物的有效性。方法:28名孕妇参与本研究。采集阴道分泌物标本测定Nugent评分，用阴道洗涤液(4 ml生理盐水)ELISA法测定HBD-2水平。结果:在妊娠早期，细菌性阴道病(BV)患者阴道HBD-2水平(42.1±19.8 pg/ml)明显低于无BV患者(350.1±68.7 pg/ml, P < 0.05)，胎膜早破患者(57.2±31.9)
{"title":"Human β-defensin-2 as a biochemical indicator of vaginal environment in pregnant women","authors":"Hideko Kotani, K. Matsubara, T. Koshizuka, K. Nishiyama, H. Kaneko, Mie Tasaka, Takashi Sugiyama, T. Suzutani","doi":"10.14390/JSSHP.HRP2018-005","DOIUrl":"https://doi.org/10.14390/JSSHP.HRP2018-005","url":null,"abstract":"Aim: Vaginal environment is an important factor in predicting threatened abortion and premature rupture of membranes (PROM) in early pregnancy. Vaginal human β -defensin-2 (HBD-2), a main antimicrobial peptide associated with innate immunity, plays multiple roles to protect the lower genital tract from microbes. This study aimed to assess the usefulness of vaginal HBD-2 as a biochemical marker for monitoring the vaginal environment in pregnant women. Methods: Twenty-eight pregnant women were enrolled in this study. Vaginal secretion samples were collected to determine Nugent scores, and vaginal washing fluid (4 ml saline) was used to measure HBD-2 levels by ELISA. Results: In the first trimester, vaginal HBD-2 levels were significantly lower in patients with bacterial vaginosis (BV) (42.1 ± 19.8 pg/ml) compared to those without BV (350.1 ± 68.7 pg/ml, P < 0.05), and in patients with PROM (57.2 ± 31.9","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14390/JSSHP.HRP2018-005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46749817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-30DOI: 10.14390/JSSHP.HRP2018-015
Konstantinos Papadakis
We discuss the contemporary practice of forceps delivery in Scotland, a country with affluent experience in operative vaginal birth. Globally, the popularity of forceps has significantly declined and undeniably it is considered by many a lost art. As a result, the volume and the complexity of the attempted forceps deliveries have lessened and more women undergo high-risk second-stage caesarean sections. Therefore, we have to draw our attention to realistic alternatives such as reinstating the skill of assisted delivery. Introducing these techniques in modern obstetrics can be a challenging task. The rates of forceps deliveries remain stable in Scotland, despite the opposite experience from most other countries. This paper is based on reviewing relevant guidelines and official national statistics. Forceps still have a place in modern obstetric practice in order to shorten labour when clinically indicated. Obstacles to forceps delivery are broadly due to the potential harm and the subsequent related medico-legal implications. Since the availability of specialists with substantial experience has been reduced, it sounds of paramount importance to conserve the learning of this valuable obstetric technique. Even more, initiatives that appoint future generations of obstetricians with expertise in performing forceps deliveries are an urgent educational priority. International recommendations and high-quality local workshops can facilitate this path.
{"title":"Forceps deliveries in Scotland: current practice, training opportunities and national trends","authors":"Konstantinos Papadakis","doi":"10.14390/JSSHP.HRP2018-015","DOIUrl":"https://doi.org/10.14390/JSSHP.HRP2018-015","url":null,"abstract":"We discuss the contemporary practice of forceps delivery in Scotland, a country with affluent experience in operative vaginal birth. Globally, the popularity of forceps has significantly declined and undeniably it is considered by many a lost art. As a result, the volume and the complexity of the attempted forceps deliveries have lessened and more women undergo high-risk second-stage caesarean sections. Therefore, we have to draw our attention to realistic alternatives such as reinstating the skill of assisted delivery. Introducing these techniques in modern obstetrics can be a challenging task. The rates of forceps deliveries remain stable in Scotland, despite the opposite experience from most other countries. This paper is based on reviewing relevant guidelines and official national statistics. Forceps still have a place in modern obstetric practice in order to shorten labour when clinically indicated. Obstacles to forceps delivery are broadly due to the potential harm and the subsequent related medico-legal implications. Since the availability of specialists with substantial experience has been reduced, it sounds of paramount importance to conserve the learning of this valuable obstetric technique. Even more, initiatives that appoint future generations of obstetricians with expertise in performing forceps deliveries are an urgent educational priority. International recommendations and high-quality local workshops can facilitate this path.","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43742982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-30DOI: 10.14390/JSSHP.HRP2018-010
Shunji Suzuki, K. Kubonoya, Y. Takeishi
This review discusses trends in mode of breech delivery in Japan. Recently, primary elective cesarean delivery rates for singleton breech pregnancies have markedly increased due to medical counseling and maternal requests. However, breech extraction skills should be preserved and passed on to future generations of obstetricians. Vaginal breech delivery may be considered if well-trained and full-time medical staff with experience performing breech deliveries are available and comprehensive informed consent is obtained. As specialists of obstetrics and gynecology, it may be necessary to acquire rudimentary techniques for vaginal breech delivery in order to perform fair and objective informed consent procedures regarding the mode of breech delivery.
{"title":"Trends in mode of delivery for breech presentation in Japan: ‘Transverse figure 8 breech delivery’","authors":"Shunji Suzuki, K. Kubonoya, Y. Takeishi","doi":"10.14390/JSSHP.HRP2018-010","DOIUrl":"https://doi.org/10.14390/JSSHP.HRP2018-010","url":null,"abstract":"This review discusses trends in mode of breech delivery in Japan. Recently, primary elective cesarean delivery rates for singleton breech pregnancies have markedly increased due to medical counseling and maternal requests. However, breech extraction skills should be preserved and passed on to future generations of obstetricians. Vaginal breech delivery may be considered if well-trained and full-time medical staff with experience performing breech deliveries are available and comprehensive informed consent is obtained. As specialists of obstetrics and gynecology, it may be necessary to acquire rudimentary techniques for vaginal breech delivery in order to perform fair and objective informed consent procedures regarding the mode of breech delivery.","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14390/JSSHP.HRP2018-010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43477212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-30DOI: 10.14390/JSSHP.HRP2018-014
Kazushi Watanabe, K. Matsubara, O. Nakamoto, J. Ushijima, A. Ohkuchi, K. Koide, S. Makino, K. Mimura, M. Morikawa, K. Naruse, Kanji Tanaka, T. Nohira, H. Metoki, I. Kawabata, S. Takeda, H. Seki, K. Takagi, M. Yamasaki, A. Ichihara, T. Kimura, S. Saito
1Department of Obstetrics and Gynecology, Aichi Medical University School of Medicine, 2Department of Obstetrics and Gynecology, Ehime University School of Medicine, 3Department of Obstetrics, Osaka City General Hospital, 4Perinatal Center, Divisions of Maternal and Fetal Medicine, Saitama Medical Center, Jichi Medical University, 5Department of Obstetrics and Gynecology, Jichi Medical University School of Medicine, 6Department of Obstetrics and Gynecology, Showa University School of Medicine, 7Department of Obstetrics and Gynecology, Juntendo University Faculty of Medicine, 8Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 9Department of Obstetrics, Hokkaido University Graduate School of Medicine, 10Department of Obstetrics and Gynecology, St. Barnabas’ Hospital, 11Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, 12Department of Obstetrics and Gynecology, Tokyo Medical University, 13Division of Public Health, Hygiene and Epidemiology, Tohoku Medical and Pharmaceutical University Faculty of Medicine, 14Department of Obstetrics and Gynecology, Tokyo Women’s Medical University, 15Department of Obstetrics and Gynecology, Saitama Medical University, 16Department of Obstetrics and Gynecology, Palmore Hospital, 17Department of Endocrinology and Hypertension, Tokyo Women’s Medical University, 18Department of Obstetrics and Gynecology, University of Toyama Hypertension Research In Pregnancy
{"title":"Outline of the new definition and classification of “Hypertensive Disorders of Pregnancy (HDP)”; a revised JSSHP statement of 2005","authors":"Kazushi Watanabe, K. Matsubara, O. Nakamoto, J. Ushijima, A. Ohkuchi, K. Koide, S. Makino, K. Mimura, M. Morikawa, K. Naruse, Kanji Tanaka, T. Nohira, H. Metoki, I. Kawabata, S. Takeda, H. Seki, K. Takagi, M. Yamasaki, A. Ichihara, T. Kimura, S. Saito","doi":"10.14390/JSSHP.HRP2018-014","DOIUrl":"https://doi.org/10.14390/JSSHP.HRP2018-014","url":null,"abstract":"1Department of Obstetrics and Gynecology, Aichi Medical University School of Medicine, 2Department of Obstetrics and Gynecology, Ehime University School of Medicine, 3Department of Obstetrics, Osaka City General Hospital, 4Perinatal Center, Divisions of Maternal and Fetal Medicine, Saitama Medical Center, Jichi Medical University, 5Department of Obstetrics and Gynecology, Jichi Medical University School of Medicine, 6Department of Obstetrics and Gynecology, Showa University School of Medicine, 7Department of Obstetrics and Gynecology, Juntendo University Faculty of Medicine, 8Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 9Department of Obstetrics, Hokkaido University Graduate School of Medicine, 10Department of Obstetrics and Gynecology, St. Barnabas’ Hospital, 11Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, 12Department of Obstetrics and Gynecology, Tokyo Medical University, 13Division of Public Health, Hygiene and Epidemiology, Tohoku Medical and Pharmaceutical University Faculty of Medicine, 14Department of Obstetrics and Gynecology, Tokyo Women’s Medical University, 15Department of Obstetrics and Gynecology, Saitama Medical University, 16Department of Obstetrics and Gynecology, Palmore Hospital, 17Department of Endocrinology and Hypertension, Tokyo Women’s Medical University, 18Department of Obstetrics and Gynecology, University of Toyama Hypertension Research In Pregnancy","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14390/JSSHP.HRP2018-014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42921613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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