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Getting Under the Skin of Seizure Monitoring: A Subcutaneous EEG Tool to Keep a Tally Over the Long Haul. 深入了解癫痫发作监测:用于长期记录的皮下脑电图工具。
IF 5.8 3区 文学 0 LITERARY REVIEWS Pub Date : 2023-08-29 eCollection Date: 2023-11-01 DOI: 10.1177/15357597231197093
Ioannis Karakis

[方框:见文本]
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引用次数: 0
Engineering cytochrome P450 enzyme systems for biomedical and biotechnological applications. 为生物医学和生物技术应用设计细胞色素 P450 酶系统。
3区 文学 0 LITERARY REVIEWS Pub Date : 2020-01-17 Epub Date: 2019-12-06 DOI: 10.1074/jbc.REV119.008758
Zhong Li, Yuanyuan Jiang, F Peter Guengerich, Li Ma, Shengying Li, Wei Zhang

Cytochrome P450 enzymes (P450s) are broadly distributed among living organisms and play crucial roles in natural product biosynthesis, degradation of xenobiotics, steroid biosynthesis, and drug metabolism. P450s are considered as the most versatile biocatalysts in nature because of the vast variety of substrate structures and the types of reactions they catalyze. In particular, P450s can catalyze regio- and stereoselective oxidations of nonactivated C-H bonds in complex organic molecules under mild conditions, making P450s useful biocatalysts in the production of commodity pharmaceuticals, fine or bulk chemicals, bioremediation agents, flavors, and fragrances. Major efforts have been made in engineering improved P450 systems that overcome the inherent limitations of the native enzymes. In this review, we focus on recent progress of different strategies, including protein engineering, redox-partner engineering, substrate engineering, electron source engineering, and P450-mediated metabolic engineering, in efforts to more efficiently produce pharmaceuticals and other chemicals. We also discuss future opportunities for engineering and applications of the P450 systems.

细胞色素 P450 酶(P450)广泛分布于生物体内,在天然产物的生物合成、异种生物的降解、类固醇的生物合成和药物代谢中发挥着至关重要的作用。P450s 催化的底物结构和反应类型多种多样,因此被认为是自然界中用途最广的生物催化剂。特别是,P450s 可以在温和的条件下催化复杂有机分子中未活化 C-H 键的区域和立体选择性氧化反应,这使得 P450s 成为生产商用药品、精细或大宗化学品、生物修复剂、香精和香料的有用生物催化剂。为了克服本地酶的固有局限性,人们在改良 P450 系统工程方面做出了巨大努力。在本综述中,我们将重点介绍不同策略的最新进展,包括蛋白质工程、氧化还原伴侣工程、底物工程、电子源工程和 P450 介导的代谢工程,以更高效地生产药品和其他化学品。我们还讨论了 P450 系统工程和应用的未来机遇。
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引用次数: 0
Heavy Alcohol Drinking Associated Akathisia and Management with Quetiapine XR in Alcohol Dependent Patients. 酒精依赖症患者与大量饮酒相关的发作性肌痉挛以及喹硫平 XR 的治疗方法
3区 文学 0 LITERARY REVIEWS Pub Date : 2016-01-01 Epub Date: 2016-10-25 DOI: 10.1155/2016/6028971
Zimple Kurlawala, Vatsalya Vatsalya

Heavy drinking contributes to involuntary body movements such as akathisia. Quetiapine has been shown to alleviate symptoms of akathisia; however, its efficacy in the alcohol dependent population is not well established. Thus, we aimed to identify efficacy of Quetiapine in treating akathisia in very heavy drinking alcohol dependent patients. 108 male and female heavy alcohol consuming study participants received 13 weeks of Quetiapine XR. Drinking history (Timeline Followback, TLFB), depression (Montgomery-Asberg Depression Rating Scale, MADRS), and movement (Barnes Akathisia Scale, BARS) measures were collected at baseline (0 W), week 6 (6 W), and week 12 (12 W). The role of drinking, symptoms of depression, and efficacy of Quetiapine for treating akathisia were assessed. In patients with no symptoms of depression (low MADRS), Quetiapine treatment decreased symptoms of akathisia. Patients with clinically significant depression (high MADRS) reported a significant increase in akathisia measures at 6 W which eventually decreased at 12 W to below baseline levels. The increase in akathisia at 6 W corresponded with a significant increase in the patients' total drinks and heavy drinking pattern. Treatment with Quetiapine progressively lowered the occurrence of akathisia in alcohol dependent patients who do not show symptoms of depression. Quetiapine treatment lowered akathisia over time in heavy drinkers who had clinically significant symptoms of depression.

大量饮酒会导致不自主的肢体运动,如 "无意识运动"。喹硫平已被证明可减轻无运动症状,但其对酒精依赖人群的疗效尚未得到充分证实。因此,我们旨在确定喹硫平治疗大量饮酒酒精依赖症患者的运动迟缓的疗效。108名男性和女性重度饮酒研究参与者接受了为期13周的喹硫平XR治疗。研究人员在基线(0 W)、第 6 周(6 W)和第 12 周(12 W)收集了饮酒史(时间线随访,TLFB)、抑郁(蒙哥马利-阿斯伯格抑郁量表,MADRS)和运动(巴恩斯运动障碍量表,BARS)测量数据。对饮酒的作用、抑郁症状以及喹硫平治疗无运动症状的疗效进行了评估。对于没有抑郁症状(MADRS评分较低)的患者,喹硫平治疗可减轻他们的自动症症状。临床症状明显的抑郁症患者(MADRS评分较高)在接受治疗6周后,其自动症症状显著增加,但在接受治疗12周后又降至基线水平以下。患者在 6 个月时出现的运动迟缓现象与患者的总饮酒量和大量饮酒模式的显著增加相对应。使用喹硫平治疗可逐步降低未出现抑郁症状的酒精依赖症患者的自动症发生率。喹硫平治疗可逐渐降低临床上有明显抑郁症状的大量饮酒者的自动症发生率。
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引用次数: 0
"I Am a Phenomenon Quite out of the Ordinary": The Notebooks, Diaries and Letters of Daniil Kharms “我是一个非常不寻常的现象”:丹尼尔·哈姆斯的笔记本、日记和信件
IF 0.1 3区 文学 Q4 Arts and Humanities Pub Date : 2016-01-01 DOI: 10.5860/choice.50-6650
Michael G. Donkin
daniil kharms, "i Am a Phenomenon Quite out of the ordinary": The Notebooks, Diaries and Letters of Daniil Kharms. translated and edited by anthony anemone and peter scotto. boston: academic studies press, 2013. 689pp. $35Daniil Kharms was born in St. Petersburg in 1905. He died in 1942, a patient in a psychiatric clinic, likely of starvation, during the Leningrad Blockade. Although he was known as a children's author during his lifetime-many of his children's books are now classics-he was unable to publish his writing "for adults." Not until long after his death, then, would Kharms earn his reputation as a poet and master of bizarre miniatures. Kharms's antic writing style brought the formal disapproval of the Soviet government, a fact that has led many to regard him as a dissident writer. This view has bolstered the misleading notion that censorship prevented him from reaching full artistic maturity. Like other repressed Soviet authors, Kharms has become something of a symbol-of the brave soul who risks everything to produce "extremely important work," which is then understood as the record of a dissident's struggle (or protest) against the authoritarian state. I Am a Phenomenon Quite Out of the Ordinary sets out to restore Kharms to mere human status, or in the editors' words, "to recover the inner life of Daniil Kharms," and collects a wide range of personal and fugitive material, previously unavailable in English, to this end. What emerges is a portrait of an amateur-not a dissident. The selections from Kharms's notebooks, diaries, and letters suggest that his most well regarded works are the expression of an idiosyncratic, implicit aesthetic program-i.e., an amateurist's philosophy-for which life and art are held to be continuous and fluid. Given the coherence and consistency of this tacit program over time, Kharms's miniatures and other well known works appear to constitute the type of writing he would have chosen to produce even under more favorable circumstances.Reading I Am a Phenomenon , one cannot help but notice that Kharms wrote as a part of ordinary life, envisioning only a small readership of friends and family. Everyday pieces of writing, such as letters, display much ingenuity and aesthetic scruple, and they have come to be included in his body of literary works. Yakov Druskin, a friend and colleague, believed that Kharms's life and work were of a piece; the diaries and notebooks go some way in confirming this view. Kharms wrote incessantly as he went about his daily rounds. According to Anemone and Scotto, the volume's editors, the author "would write on the tram, in a sauna, at concerts, while visiting friends, visiting his aunt, or in the middle of a fight with his wife." In I Am a Phenomenon important pieces of Kharms's literary output share notebook pages with grocery lists, schemes, and memoranda of romantic meetings. Although some of the writing is of excellent quality, very little is consciously marked out as serious, pl
丹尼尔·哈姆斯,“这是一个非常不寻常的现象”:丹尼尔·哈姆斯的笔记本,日记和信件。Anthony anemone和Peter scotto翻译和编辑。波士顿:学术研究出版社,2013。689页。丹尼尔·哈姆斯1905年出生于圣彼得堡。1942年,在列宁格勒封锁期间,他死于精神病诊所的病人,可能是饥饿。尽管他生前以儿童作家而闻名——他的许多儿童书籍现在都是经典之作——但他无法为“成人”出版自己的作品。直到他死后不久,哈尔姆斯才赢得了诗人和奇异微缩画大师的声誉。哈姆斯古怪的写作风格招致了苏联政府的正式反对,这一事实导致许多人将他视为持不同政见的作家。这种观点支持了一种误导性的观念,即审查制度阻碍了他达到完全的艺术成熟。像其他被压制的苏联作家一样,哈姆斯已经成为一种象征——勇敢的灵魂冒着一切危险创作“极其重要的作品”,这些作品后来被理解为持不同政见者对专制国家的斗争(或抗议)的记录。《我是一种非常不同寻常的现象》的目的是将哈姆斯还原为纯粹的人类,或者用编辑的话说,“恢复丹尼尔·哈姆斯的内心生活”,为此,作者收集了大量个人和逃亡的材料,这些材料以前在英语中是无法获得的。呈现出来的是一个业余爱好者的肖像,而不是一个持不同政见者。从哈尔姆斯的笔记本、日记和信件中挑选出来的作品表明,他最受好评的作品是一种独特的、含蓄的审美程序的表达。这是一种业余爱好者的哲学,认为生活和艺术都是连续的、流动的。考虑到随着时间的推移,这种默契的程序的连贯性和一致性,哈姆斯的微缩画和其他知名作品似乎构成了他即使在更有利的环境下也会选择创作的写作类型。读到《我是一种现象》,人们不禁会注意到,哈尔姆斯把写作作为日常生活的一部分,只把朋友和家人作为一小部分读者。日常写作,如信件,显示出许多独创性和审美上的顾虑,这些都被包括在他的文学作品中。他的朋友兼同事雅科夫·德鲁斯金(Yakov Druskin)认为,哈姆斯的生活和工作是一体的;日记和笔记本在某种程度上证实了这一观点。卡姆斯在每天的巡视中不停地写信。据该书的编辑阿尼莫尼和斯科托说,这位作家“会在有轨电车上、桑拿浴室里、音乐会里、拜访朋友时、拜访姑姑时,或者在和妻子吵架时写作。”在《我是一种现象》一书中,哈姆斯的重要文学作品与购物清单、计划和浪漫会议的备忘录分享了笔记本页面。尽管有些作品质量上乘,但很少有意识地将其标记为严肃的、有计划的,或者与作者日常生活中的普通语流区别开来。人们可以感觉到,即使是哈姆斯最重要的作品也是自发创作的,它们的文学价值是偶然事件和技巧,也许是灵感的混合结果,而不是因为哈姆斯做出了一些特别的努力,使自己远离社会世界或他的实际事务。这种影响是哈尔姆斯业余写作实践的结果,人们只有在阅读他的著名作品和次要作品时才能感受到它,因为它们是在几天、几周、几个月和几年里积累起来的。通过让英语读者第一次以这种方式接近哈尔姆斯,Anemone和Scotto提供了一个重要的服务。人们确实希望他们至少能多收录十几首哈姆斯的经典微缩画和诗歌——比如《今天我什么也没写》中的那些——以便在他日常生活的背景下,更有力地将作者置于他权力的巅峰。…
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引用次数: 3
From THE PENTAGON 来自五角大楼
IF 0.1 3区 文学 Q4 Arts and Humanities Pub Date : 2014-10-01 DOI: 10.2307/j.ctv7n0c18.10
Jacqueline Waters
A person has to live with the facts.Say something critical-tell everyone, for instancethat you find your boss eerieor a hypocriteand it's you who'll be associatedin your listener's mind (more or less forever)with eeriness, and withhypocrisy.You live. You complete sixteen of the seventeen tasks assigned to you.For the seventeenth, you call your supervisor.No need to sign in today, he says. No work.You find a stall and close the door, [laughter]*I start by asking everyone what they think, he said.I work it in there with their nameand a few things about hometowns.This one, eyes closed, accounting for it all, drawing deep invisiblelines past which one does not walk, retiring to a small apartment,reading a trade magazine before bed, a little scenario of vegetablescooling on an upturned lid...The best way to open a movie, he said, is with an auction housescene. Get your audienceto root fora buyer!*Bland detail: You told the hotel clerk about the problem with thevending machine. She moved parts of her face into second position,told you to fill out a waiver and sign it.If you're shy you're at the mercy of people considerate of peoplewho are shyOne afternoon as you left the building you saw the supervisorchaining his bicycle to a parking meter. You stood there, outside thehealth food restaurant. You saidHelloand he saidAs if.Again, if you're shy your main friends will be people interested inpeople who are shy.*This isn'tsafe infact anyonecan easilyget at youthey'll searchyour bodyfor two rowseach carryinghundreds ofidentical teethforced togetherby a sliderhiding in itsthroat aY-shapedchanneland holdsomethinghot to ittill youbreak openalongperforatedlines.Or try sweetener packetsstuffed inlittle yellowgratuity envelopes.That's grace, the filled envelope.That full meal on thatsturdy plate.*We have to get this project launched before the announcement, theysaid. So you can see our problem here.I can see your problem there. You're just going to eat a roll orwhatever that brown block is.An air of costliness: crumpled wrappers, torn cardboard, pried-apartplastic clams.Treat all conversation as ad hominem argument, he said. Always thinkabout what you might be able to find out about them.Them. What we all called: filler.Filler die. First the men of the family, usually, and then the women notlong after.Or it's the women who die, and the men live another ten or twentyyears, being better able than women to do the business of living, andthen the men die.And then the children die, one by one, and their funerals are held onSaturdays and Sundays in buildings that look like houses but liesuspiciously close to the town center, on a corner, or main road,immaculate residences zoned as businesses. …
一个人必须面对现实。说一些批评的话——告诉所有人,比如你觉得你的老板很可怕或者是个伪君子——那么在你的听众的脑海里(或多或少永远)你就会和怪异和伪君子联系在一起。你住。你完成了分配给你的17项任务中的16项。第十七次,你打电话给你的主管。他说,今天不需要签到。没有工作。他说:“你找个隔间,关上门,我先问每个人的看法。”我在那里写着他们的名字和一些关于家乡的事情。这一个,闭着眼睛,解释了这一切,画出了一个人无法走过的深深的看不见的线,隐退到一个小公寓里,睡前看一本行业杂志,一个小小的场景,蔬菜在一个上翻的盖子上冷却……他说,电影最好的开场方式是在拍卖行里。让你的观众去寻找买家!乏味的细节:你把自动售货机的问题告诉了酒店职员。她把脸的一部分移到第二位置,让你填写弃权书并签字。一天下午,当你离开大楼时,你看到管理员正把他的自行车停在停车收费表前。你站在那里,在健康食品餐厅外面。你说“你好”,他说“是的”。同样,如果你很害羞,你的主要朋友将是那些对害羞的人感兴趣的人。这是不安全的,事实上任何人都可以很容易地接近你,它们会在你的身体里搜出两排,每一排都携带着数百颗相同的牙齿,这些牙齿被隐藏在喉咙里的一个滑梯连在一起,呈ay状,它们会抓住一些东西,直到你沿着打孔线打开。或者试试装在黄色小信封里的甜味剂包。这就是恩典,装满的信封。在那个结实的盘子里吃一顿丰盛的饭。*他们说我们必须在宣布之前启动这个项目。所以你可以看到我们的问题。我明白你的问题了。你只需要吃一个面包卷或者其他棕色的东西。一种昂贵的气氛:皱巴巴的包装纸,撕烂的纸板,被撬开的塑料蛤蜊。他说,把所有的谈话都当作人身攻击。总是想想你能从他们身上找到什么。我们都称之为:填充物。填料死去。通常首先是家里的男人,然后是不久之后的女人。或者是女人死了,男人又活了10年或20年,比女人更有能力活下去,然后男人就死了。然后孩子们一个接一个地死去,他们的葬礼在周六和周日举行,地点看起来像房子,但可疑地靠近镇中心,在一个角落或主干道上,这些整洁的住宅被划为商业区。…
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引用次数: 0
Modern Madrigalisms: Elliott Carter and the Aesthetics of Art Song 现代牧歌主义:艾略特·卡特与艺术歌曲美学
IF 0.1 3区 文学 Q4 Arts and Humanities Pub Date : 2014-06-22 DOI: 10.1163/9789004342132_018
L. Kramer
In 1978 I attended the premiere of Elliott Carter's Syringa for mezzo soprano, bass-baritone, and chamber ensemble, a setting, so to speak (but we shouldn't) of John Ashbery's 1977 poem of the same name. As befits the music's two voices, which sing at the same time but not together, dual but not a duet, Syringa affected me doubly. It changed my view of Carter and it showed me possibilities of vocal writing that Carter himself would subsequently leave unrealized. My familiarity with Carter at the time of the premiere was limited to four or five compositions, an unsurprising number given how relatively sparse his output had been. The only piece of Carter's I genuinely enjoyed had been his First String Quartet (1950-51), which seemed to me to accomplish with great expressive power the task--giving each instrument in the ensemble a radically individual identity--more famously addressed by his Second String Quartet (1959), a piece I found arid. "I regard my scores," Carter explained in a much-quoted statement, "as scenarios, auditory scenarios, for performers to act out with their instruments, dramatizing the players as individuals and participants in the ensemble." (1) But even in the First String Quartet, and in a later work that fascinated me without giving me much pleasure, the Double Concerto for Harpsichord and Piano with Two Chamber Orchestras (1961), this individualization seemed more a theoretical horizon than an acoustic reality. A recording of the concerto could not do justice to the division of forces, but even in live performance, with the groups separated spatially to underline their being equipped with their own distinct pitches, rhythms, and tempos, the dense texture and complex layering of sound made it difficult to keep the individuals individual. The music seemed to implode into the compositional voice of a monolithic persona, a rugged original who would later declare, "I just can't bring myself to do something that someone else has done before," a distinctly American figure of Emersonian self-reliance whose nom de plume was Elliott Carter. (2) Syringa fixed all that. Ashbery's poem is a reworking of the Orpheus legend and the music is a reworking of the poem, which Carter does not so much set to music as refract. The mezzo does indeed sing Ashbery's text but at the same time the baritone sings a series of ancient Greek fragments telling various aspects Of the original myth. The two singers not only sing in two different languages, one dead, one living, but also in two different styles, the mezzo's restrained and spare, the baritone's impassioned and widely spanned. In performance these differences formed the stuff of a genuinely audible scenario. The differences in personality and musical identity between the work's two vocal personae were clear without being obvious, and the differences clearly mattered: the baritone, a not-quite Orpheus, traced fervent arabesques of desire and mourning that enveloped but never reached the mezzo,
1978年,我参加了艾略特·卡特(Elliott Carter)为女中音、男中音和室内乐合奏的《琴瑟》(Syringa)首演,可以说(但我们不应该)是约翰·阿什伯里(John Ashbery) 1977年的同名诗歌的背景。这首歌的两种声音同时歌唱而不是在一起歌唱,是双重的而不是二重唱,这与它对我的影响是双重的。它改变了我对卡特的看法,它向我展示了卡特本人后来没有实现的声乐写作的可能性。首演时,我对卡特的了解仅限于四到五首曲子,考虑到他的作品相对较少,这个数字并不令人惊讶。我唯一真正喜欢卡特的作品是他的《第一弦乐四重奏》(1950-51),在我看来,这首歌似乎以巨大的表现力完成了任务——赋予合奏中的每一个乐器一种彻底的个人身份——他的《第二弦乐四重奏》(1959)在这方面表现得更为著名,我觉得这首歌很乏味。“我把我的乐谱,”卡特在一次被广泛引用的声明中解释说,“看作是场景,听觉场景,让表演者用他们的乐器表演,把演奏者作为个体和整体的参与者戏剧化。”(1)但是,即使在《第一弦乐四重奏》中,以及后来的一部令我着迷却没有给我太多乐趣的作品——《与两个室内管弦乐队合作的拨弦键琴和钢琴双协奏曲》(1961)中,这种个性化似乎更多的是一种理论视野,而不是一种听觉现实。协奏曲的录音不能公正地划分力量,但即使在现场表演中,小组在空间上分开,以强调他们拥有自己独特的音高,节奏和速度,密集的质地和复杂的声音层次使得很难保持个体的个性。音乐似乎被一个单一人物的作曲声音所瓦解,一个粗犷的原创者后来宣称,“我就是不能让自己去做别人以前做过的事情”,一个典型的爱默生式自力更生的美国人物,他的笔名是艾略特·卡特。(2)丁香解决了这一切。阿什伯里的诗是对俄耳甫斯传说的改编音乐是对这首诗的改编,卡特并没有把它谱成音乐,而是进行了折射。女中音确实演唱了阿什伯里的文本,但与此同时,男中音演唱了一系列古希腊片段,讲述了原始神话的各个方面。这两位歌手不仅用两种不同的语言演唱,一种是死的,一种是活的,而且还有两种不同的风格,女中音的克制和节制,男中音的慷慨激昂和广泛跨越。在表演中,这些差异形成了一个真正可听的场景。这部作品的两个声部人物在性格和音乐身份上的差异是显而易见的,但并不明显,而且这种差异显然很重要:男中音,不完全是俄耳甫斯,描摹出热情的阿拉伯式的欲望和哀悼,这些欲望和哀悼笼罩着中音,但从未到达中音,不完全是欧律狄刻(在地下世界也找不到);在古代和现代的不同中角色的转换(这是俄耳甫斯逗留的地方),对她来说,男中音的抱怨就像一种不完全属于她的无意识。欧律狄刻输给了俄耳甫斯,不是在过去,而是在未来。在未来,无论谁回头或不回头,她都听不见俄耳甫斯的话。这两个复合人物的声音给合奏的乐器赋予了他们自己的某种能动性。每一个声音都能说话,也的确会说话,虽然目的并不总是可知的。那个铁板一块的人物已经离开了大楼。在我看来,Syringa似乎在冗长而老套的文字与音乐的关系历史中开辟了一系列新的可能性——不仅是多样性的可能性和有效的声乐行为的可能性,这些行为不能被限制在说话者和听众的网格中,而且还有音乐中声乐表达的可能性,它超越了模仿,同时又不会退缩到抽象。…
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引用次数: 0
Being Numerous: Poetry and the Ground of Social Life 群居:诗歌与社会生活的根基
IF 0.1 3区 文学 Q4 Arts and Humanities Pub Date : 2013-07-01 DOI: 10.5860/choice.48-6760
R. Eldridge
Oren Izenberg, Being Numerous: Poetry and the Ground of Social Life. Princeton, NJ: Princeton University Press, 201 1.234pp. $29.95In Being Numerous: Poetry and the Ground of Social Life, Oren Izenberg relentlessly raises questions about the tasks, strategies, values, and accomplishments of the most difficult modern poetry in relation to deep issues regarding the nature of persons as such. The phrase "ground of social Ufe" focuses on personhood as something given, primitive, immediate, and distributed by nature equauy among aU human beings, in contrast to personhood understood as something that involves specific identity, pubhc mastery of language, and responsibihty for routines of sociaUy inteUigible action-personhood as an achievement rather than a given. Traditionally, Izenberg notes, we take the lyric subject or "the artifice of voice in the poem to offer something like a model or a theory of the person.... The poem gives shape to the concept of the person who can think, say, and make these things." This traditional understanding focuses, one might say, on persons in the second sense at the expense of the first-on the mastery of voice rather than its givenness as not-yet-formed potential. Izenberg then undertakes to redress this imbalance and to describe and praise a poetry primarily of personhood as potential. This approach leads him to taxonomize varieties of modern and contemporary poetry-ontological-impersonal versus expressive-personal-in a somewhat different way than the often used oppositions of postromantic/postmodern, symbohst/constructivist, and traditionahst/avant-garde. But Izenberg's most radical claims go beyond merely redrawing old maps. Izenberg is specificaUy worried that the traditional understanding of lyric as enactment of exemplary articulated subjectivity is by its very nature comphcit in "a set of civuizational crises," including "decolonization and nation formation, the levehng of consumer culture.. .genocide and the specter of total annihilation." The thought here is that any effort to teU this story of a sequence of perceptions, thoughts, feehngs, and verbal articulations of them as exemplary, formed for the sake of sympathy and resonance, inevitably suppresses the independence and distinctiveness of the stories of some others.Izenberg poses against this traditional picture of lyric a less personally expressive poetry of pure "attentiveness" and of "the greatest possible opening of the self"-to other people and to contingencies that are simply experienced sequentially and registered paratactically. This poetry turns away from emplot- ment, articulation, and formai construction. It is hostile to art and artfulness, "deliberately hostile... to any reading." This poetry of the non-poem seeks to make something happen, to awaken its readers to the quite different contingencies of their own Uves in "being numerous"-that is, in being simply cast into the world along with others, where no common course of thought, feeling, o
奥伦·伊森伯格:《众多:诗歌与社会生活的基础》。普林斯顿,新泽西州:普林斯顿大学出版社,2011年,1.234页。29.95美元在《数量众多:诗歌与社会生活的基础》一书中,奥伦·伊森伯格无情地提出了关于最困难的现代诗歌的任务、策略、价值观和成就的问题,这些问题与有关人的本质的深层问题有关。“社会生活的基础”这一短语将人格视为一种被赋予的、原始的、直接的、由自然平等地分配给所有人类的东西,与之形成对比的是,人格被理解为涉及特定身份、对语言的公共掌握和对社会日常活动的责任——一种可理解的行动——人格是一种成就,而不是一种给予。伊森伯格指出,传统上,我们把抒情主题或“诗歌中声音的技巧”作为提供一个人的模型或理论....这首诗塑造了一个能思考、能说话、能做出这些东西的人的概念。”有人可能会说,这种传统的理解,以牺牲第一种意义为代价,把重点放在第二种意义上的人身上——放在对声音的掌握上,而不是把它作为尚未形成的潜力来给予。然后,伊森伯格致力于纠正这种不平衡,并将人格作为潜在的诗来描述和赞美。这种方法使他对现当代诗歌的种类进行了分类——本体论的、非个人的和表现性的、个人的——与通常使用的后浪漫主义/后现代主义、象征主义/构成主义、传统主义/前卫的对立有所不同。但伊森伯格最激进的主张不仅仅是重新绘制旧地图。伊森伯格特别担心的是,传统上对抒情的理解是一种典型的主体性的制定,就其本质而言,它与“一系列文明危机”是复杂的,包括“去殖民化和民族形成,消费文化的水平……种族灭绝和彻底灭绝的幽灵”。这里的想法是,任何将这个故事的一系列感知、思想、情感和语言表达作为典范的努力,都是为了同情和共鸣而形成的,不可避免地压制了其他一些故事的独立性和独特性。与传统的抒情诗相反,伊森伯格提出了一种不那么具有个人表现力的诗歌,纯粹的“专注”和“自我最大可能的开放”——对其他人和偶然事件,只是顺序地经历和并列地记录。这首诗远离了雇佣、表达和形式建构。它敌视艺术和技巧,“故意敌视……任何阅读。”这种非诗的诗试图让一些事情发生,唤醒读者意识到他们自己在“众多”中的完全不同的偶然性——也就是说,他们只是和其他人一起被扔进这个世界,在这个世界上,没有任何共同的思想、感情或行动路线可以不伴随着压抑和恐怖而被策划。它的口号是“制造和伪造……同时发生”的策兰理念。然后,离开制作(以及表达、形成和歌唱),进入意合记录、注意、结巴和疑惑。乔治·奥彭可以说是伊森伯格研究的核心人物。短语“众多”——简单地与他人在一起,没有任何共同的情节——取自奥本斯1968年长诗的标题,它也出现在伊森伯格命名为“克鲁索的沉默”的一段结尾。在这首诗的沉默中,简单存在的陈述对伊森伯格有着深刻的意义:用奥彭的话来说,诗歌“仍然过于流畅”。“我希望这首诗什么都不是,透明的,听不见的,不存在,”他引用了奥彭的另一部作品。于是,伊森伯格从诗歌转向了奥彭的日记本,在那里他发现了一种听不见的秘密“暗歌”,它以“倾听的决心”取代了表达和主张。…
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引用次数: 14
The Princeton Encyclopedia of Poetry and Poetics 普林斯顿诗歌和诗学百科全书
IF 0.1 3区 文学 Q4 Arts and Humanities Pub Date : 2013-01-01 DOI: 10.1093/acref/9780190681173.001.0001
Kent Johnson
Marjorie Perloff, Avant-Garde Poetics, and The Princeton Encyclopedia of Poetry and Poetics The new fourth edition of the Princeton Encyclopedia of Poetry and Poetics should be commended on many fronts, not least for its addition of essays on numerous "Third-World" ethnic and national poetries, relegated in previous editions (especially the first two, improved somewhat in the third) to brief discussions within schematic entries devoted to whole continents. It's therefore strange and disconcerting that the entry titled "Avant-Garde Poetics," authored by the justly esteemed critic Marjorie Perloff, should echo the lamentable biases of past editions. The stunning omissions in Perloff's entry fly directly in face of the more capacious, internationalist gestures of the new Princeton. (1) Moreover, the entry's myopic purview is in dramatic contradiction with the internationalist outlook that the avant-garde itself (even on its minority right wing!) has long maintained at its ideational core. "Avant-Garde Poetics" is substantial--as long, in fact, as most of the entries given to national poetries, save the ones reserved for the United States and England, which are, Ut Imperium Poesis, multiply longer than any others. It names dozens of poets (and other artists) and a large number of tendencies and movements, from the era of Rimbaud up to the US "post-avant" present. And with exception of a passing reference to the Brazilian brothers Augusto and Haroldo de Campos and their Con cretista moment, not a single poet or group outside the Anglo-American/European experience is acknowledged. (2) The entire Iberian Peninsula, event goes missing! How could such a skewed summation have made its way into the new, more globally minded Princeton? I wonder if Perloff might explain her focus on what the state forms dub "Caucasian [non-Hispanic]" writers by saying that the strict concern of her entry is the "historical avant-garde," the European movements that Renato Poggioli and Peter Burger cover in their classic studies of same title, Theory of the Avant-Garde. (3) Yet, as noted above, this is clearly not the case: she brings in any number of Western-Caucasian figures and groups emerging after the initial epoch-making explosions--many of them less influential, historically speaking, than key actors she leaves out. Among the many indispensable authors of the radical tradition absent from Perloff's culturally crimped account, here are a baker's half-dozen whose works and thought, in intimate conversation with the avant-garde's very origins or later legacy, have altered the course of world poetry. I'm cognizant that much of the information will not be new to many readers of this journal. But given the somewhat confounding case at issue, some kind of anecdotal emphasis seems in order. Is the passing over by Perloff of a giant vanguard poet like Vicente Huidobro perchance an innocent cut-and-paste glitch? His announcement of Creacionisrno appears in Chile even before he arr
《普林斯顿诗歌与诗学百科全书》第四版在许多方面都值得称赞,尤其是它增加了许多关于“第三世界”民族和国家诗歌的文章,在以前的版本中(尤其是前两版,第三版有所改进),在专门讨论整个大陆的概要条目中进行了简短的讨论。因此,由广受尊敬的评论家马乔里·佩洛夫(Marjorie Perloff)撰写的题为“先锋诗学”(Avant-Garde Poetics)的条目,竟然呼应了过去版本令人遗憾的偏见,这令人感到奇怪和不安。佩尔洛夫的条目中令人震惊的遗漏直接与新普林斯顿更加宽容的国际主义姿态背道而驰。此外,该条目的短视范围与先锋本身(即使是其少数右翼!)长期以来在其思想核心中坚持的国际主义观点形成了戏剧性的矛盾。《先锋派诗学》篇幅很长——事实上,与大多数国家诗歌的条目一样长,除了留给美国和英国的那些,它们比其他任何条目都要长。书中提到了几十位诗人(和其他艺术家)的名字,以及从兰波时代到美国“后前卫”时代的大量趋势和运动。除了偶尔提到巴西的奥古斯托和哈罗多·德·坎波斯兄弟以及他们的共产主义时刻外,没有一个英美/欧洲经验之外的诗人或团体被承认。(2)整个伊比利亚半岛,事件失踪!这样一个扭曲的总结是如何进入更具全球意识的新普林斯顿的呢?我想知道佩尔洛夫是否可以解释她对国家形式所称的“高加索[非西班牙裔]”作家的关注,她说她的条目严格关注的是“历史先锋派”,即雷纳托·波焦利和彼得·伯格在他们同名的经典研究《先锋派理论》中所涉及的欧洲运动。(3)然而,如上所述,事实显然并非如此:她引入了在最初的划时代的爆发之后出现的许多西方高加索人物和团体——从历史上讲,他们中的许多人的影响力不如她遗漏的关键人物。在佩尔洛夫被文化束缚的叙述中,激进传统的许多不可或缺的作者都缺席了,这里有六位作家,他们的作品和思想,与先锋派的起源或后来的遗产进行了亲密的对话,改变了世界诗歌的进程。我知道很多信息对这本杂志的读者来说并不新鲜。但考虑到这个令人困惑的案例,一些轶事式的强调似乎是合理的。佩尔洛夫对维森特·韦多布罗(Vicente Huidobro)这样的伟大先锋诗人的忽略,是否可能是一个无辜的剪切和粘贴错误?1916年,他抵达巴黎,与阿波利奈尔、布列塔尼、Reverdy、Gris、毕加索等人喝酒、争论,在此之前,他就在智利宣布了Creacionisrno。早在1912年至1913年,他就在创作和出版书法作品,比阿波利奈尔更早。他是当时巴黎最重要的杂志《南北方》(Nord-Sud)发展的核心人物。他认识巴黎先锋派的每一个人,而每个人也都认识他——尤其是他、里弗迪和查拉,成为了亲密的合作者。他的创造主义纲领比达达主义早了好几年,甚至比达达主义早了几年,并且预见了后来超现实主义和激进现代主义的各种其他表达所阐述的原则,尤其是在它呼吁诗歌作为一种完全有机的现实的地位,不是模仿自然的外表,而是对其动态力量和运作的本体论投射:“诗人啊,为什么要歌颂玫瑰?”他写道。“让它们在诗中开花。”他继续通过画诗来实现他的想法。然后,从1919年开始,他开始写《阿尔塔佐》,这是现代主义最伟大的史诗之一。…
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引用次数: 3
The Needs of Ghosts: On Poems from the Margins of Thom Gunn's Moly 鬼魂的需要:汤姆·葛恩《Moly》边缘诗选
IF 0.1 3区 文学 Q4 Arts and Humanities Pub Date : 2011-01-01 DOI: 10.1057/9780230119932_7
Devin Johnston
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引用次数: 0
The Bitter Withy 苦葡萄
IF 0.1 3区 文学 Q4 Arts and Humanities Pub Date : 2010-10-01 DOI: 10.1093/nq/s10-iv.83.84
Tim Erickson
Donald Reveil, The Bitter Withy. Farmington, Maine: Alice James Books, 2009.61pp. $15.95At a recent reading from The Bitter Withy, Donald Revell read "Cant Stand It," which begins:I hear the elephant musicOf the playground's rusted swings, and up,Up higher, then down again,Happy children take the sound.No snakes can read.Walking across the ocean,Walking on flowers nowhere to be seen,I walk on gold.When he read the line "No snakes can read," the audience laughed at the non sequitur and Revell smiled winningly. And though it is certainly a non sequitur, the allusion to Eden, following a playground scene, is instructive: The Bitter Withy is focused precisely on linking the material to the metaphysical, the quotidian to the eternal. In "Cant Stand It," Revell grants, "A diamond is a diamond. / A cloud is a cloud that looks like one," but insists, too, that Heaven is actual, a place where the rusty swings of the playground are transfigured so that they "make no sound." In "Lissen," conversely, there are sounds only the dead can hear:There is a sound in birdsongJust before the song,And you can hear it,Though only a few,And those are reflected on lake waterlike beautiful ghostsAlways just at sunrise,Do.Tell the truth exactly, it will makeno sense.The title's place name is a pun on "listen," one that extends to "no sense." The "truth," the miraculous, will not square with our senses. Such sentiment is peppered throughout The Bitter Withy, sometimes as plainly as in the statement, "What I need / Is not to look at all" ("Little Bees"), and in the strange and fine poem, "Drought":Eyesight is nobody.Perspective dies before it lives,And it lives a long time after deathLike birdsong.When I die, I will begin to hearThe higher frequency. . .This skepticism of sense data brings Revell, as ever, very close to Blake: "If the doors of perception were cleansed everything would appear to man as it is, infinite." These poems do not deny materiality; they insist that everything transcends materiality, that everything that lives is holy.To that end, Revell purchases a good deal of stock in backyard flora and fauna. Flowers and trees, bugs, birds, rabbits, dogs, predators and prey are all "parallel animals," figures of our shared vulnerability to death and of our animal impulse toward destruction, and all holy (as in the poem "Nemesis"). In "Against This Quiet," a moving elegy for the poet's mother that includes phrases from John Ashbery s "Clepsydra," Revell imagines that a dreaming dog- at once a predator and quite literally holy- is chasing a lizard:In the long way back out of sadness,In new dark passages,He accepts miter and tonsure.That's not right.The dog's really killed him.The dog is just as able to accept miter and tonsure as we, and he is as able to kill and be killed. His experience is no different, his blessings and curses no different. This is the argument of The Bitter Withy, and if we accept the premise that every animal's experience on this earth is the sa
唐纳德·雷维尔,《苦葡萄》。缅因州法明顿:爱丽丝·詹姆斯出版社,2009.61页。15.95美元最近,唐纳德·雷维尔朗读了《苦柳树》中的一段“我受不了”,开头是:我听到大象的音乐,在操场生锈的秋千上,向上,向上,然后又向下,快乐的孩子们跟着声音走。蛇不识字。走过海洋,走在看不见的花朵上,走在黄金上。当他念到“没有蛇能读书”这句台词时,观众们对这句不合逻辑的话哈哈大笑,雷维尔露出了胜利的微笑。虽然这肯定是一个不合逻辑的推论,但在游乐场的场景之后,对伊甸园的暗示是有启发意义的:《苦萎》的重点是将物质与形而上学联系起来,将日常与永恒联系起来。在《不能忍受》一书中,雷维尔承认,“钻石就是钻石。/一朵云是一朵看起来像云的云,”但他也坚持认为天堂是真实的,在那里,操场上生锈的秋千被变形了,所以它们“发出不出声音”。相反,在《利森》中,有一些只有死人才能听到的声音:在鸟鸣中有一种声音,就在歌声之前,你能听到它,虽然只有少数,那些反射在湖面上的声音,就像美丽的幽灵,总是在日出的时候,做。实话实说,这样就没有意义了。标题的地名是“听”的双关语,延伸到“没有感觉”。“真相”,奇迹,不会与我们的感官相符。这样的情感贯穿于《苦枯草》中,有时就像“我需要的/就是根本不看”(《小蜜蜂》)这句话一样直白,有时也像那首奇怪而优美的诗《干旱》中那样:视力不是什么人。远景在它存在之前就消失了,在它死后又像鸟鸣一样长存。当我死后,我将开始听到更高的频率……这种对感觉数据的怀疑使雷维尔一如既往地非常接近布莱克:“如果感知的大门被净化,一切都将呈现给人类,因为它是无限的。”这些诗并不否认物质性;他们坚持一切都超越物质性,一切生命都是神圣的。为此,雷维尔在后院购买了大量的动植物。花和树、虫子、鸟、兔子、狗、掠食者和猎物都是“平行的动物”,是我们对死亡的共同脆弱性和我们对毁灭的动物冲动的象征,都是神圣的(就像诗《复仇女神》(Nemesis)中所写的那样)。在《反对寂静》这首为诗人母亲写的动人的挽歌中,雷维尔想象了一只做梦的狗——既是捕食者,又是真正神圣的——正在追逐一只蜥蜴:在从悲伤中走出来的漫长路上,在新的黑暗段落中,他戴上了帽子,剪了头发。这是不对的。那条狗真的把他咬死了。狗和我们一样能接受人的头发和头发,它也能杀人和被杀。他的经历没有什么不同,他的祝福和诅咒也没有什么不同。这就是《苦枯萎》的论点,如果我们接受这个前提,即地球上所有动物的经历都是一样的,再加上某种诺斯底主义的坚持,即万物都有灵魂,那么日常与永恒之间的联系就很难否认了。像这样有远见的逻辑在主题上与纽约学派的距离,就像雷维尔现在的家拉斯维加斯与他在布朗克斯的出生地的距离一样遥远。但他的技巧——语言的戏谑,尖锐的转向,形象对形象,观念对观念——无疑标志着他是那群诗人的继承人。与此同时,雷维尔宣称自己是一名基督徒,他的演讲者渴望一个基督教的天堂,这使他成为极少数以任何方式严肃对待基督教的当代诗人之一。仅这一事实就使雷维尔的诗很有趣:一个异端的纽约学生同时也是一个异端的基督徒这样承认他的圣徒(在一首诗《蟋蟀》中,献给芭芭拉·盖斯特):圣威廉·布莱克,为我祈祷;圣兰波,为我祈祷;圣安东尼·阿尔托,用一个烟头在我的脑袋里烙上新的眼睛。…
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