Pub Date : 2022-09-30DOI: 10.35845/kmuj.2022.21668
Tarbia Hamid, Muhammad Ahsan Khan, Ramsha Hamid
observational study of breast fibroadenomas
乳腺纤维腺瘤的观察研究
{"title":"THE BREAST MOUSE: AN OBSERVATIONAL STUDY OF BREAST FIBROADENOMAS IN THE PAKISTANI POPULATION","authors":"Tarbia Hamid, Muhammad Ahsan Khan, Ramsha Hamid","doi":"10.35845/kmuj.2022.21668","DOIUrl":"https://doi.org/10.35845/kmuj.2022.21668","url":null,"abstract":"observational study of breast fibroadenomas","PeriodicalId":42581,"journal":{"name":"Khyber Medical University Journal-KMUJ","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42677471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-30DOI: 10.35845/kmuj.2022.23088
Saima Abid, Akif Ullah, Naveeda Khan, Ramsha Sarwar, Hamid
Bpreva len t f ema le cancer worldwide, with estimated global figures of 2.3 million new cases th (11.7% of all cancer) in 2020. It is the 5 leading cause of cancer-related mortality 1,2 worldwide, 685,000 deaths. Exact cause of the breast cancer is not known however, genetic factors like BRCA 1, 2 & p 53 gene mutations play an important role. Other risk factors include female gender, growing age, high estrogen exposure, obesity, lack of exercise, stress, early menarche and late 3 menopause etc.
{"title":"BREAST CANCER: EARLY DETECTION INITIATIVE IN PAKISTAN","authors":"Saima Abid, Akif Ullah, Naveeda Khan, Ramsha Sarwar, Hamid","doi":"10.35845/kmuj.2022.23088","DOIUrl":"https://doi.org/10.35845/kmuj.2022.23088","url":null,"abstract":"Bpreva len t f ema le cancer worldwide, with estimated global figures of 2.3 million new cases th (11.7% of all cancer) in 2020. It is the 5 leading cause of cancer-related mortality 1,2 worldwide, 685,000 deaths. Exact cause of the breast cancer is not known however, genetic factors like BRCA 1, 2 & p 53 gene mutations play an important role. Other risk factors include female gender, growing age, high estrogen exposure, obesity, lack of exercise, stress, early menarche and late 3 menopause etc.","PeriodicalId":42581,"journal":{"name":"Khyber Medical University Journal-KMUJ","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48995553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-30DOI: 10.35845/kmuj.2022.21660
B. Naz, Syeda Shahida, Muhammad Kashif Batool, Fida, Muhammad Zohaib Khan
OBJECTIVE: To develop a valid and reliable tool to measure infertility-specific emotional and social distress (ESD) among men and women
目的:建立一种有效、可靠的测量男性和女性不孕症特异性情绪和社会困扰(ESD)的工具
{"title":"CONSTRUCTION AND VALIDATION OF EMOTIONAL AND SOCIAL DISTRESS SCALE FOR MEN AND WOMEN DIAGNOSED WITH INFERTILITY: FURTHER EVIDENCE OF ITS CONSTRUCT VALIDITY AND PSYCHOMETRIC PROPERTIES","authors":"B. Naz, Syeda Shahida, Muhammad Kashif Batool, Fida, Muhammad Zohaib Khan","doi":"10.35845/kmuj.2022.21660","DOIUrl":"https://doi.org/10.35845/kmuj.2022.21660","url":null,"abstract":"OBJECTIVE: To develop a valid and reliable tool to measure infertility-specific emotional and social distress (ESD) among men and women","PeriodicalId":42581,"journal":{"name":"Khyber Medical University Journal-KMUJ","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48269629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-30DOI: 10.35845/kmuj.2022.20898
Romana Ijaz, Mussarat Summaira Naz, Jabeen Khan, H. Bibi
Moderating role of
的调节作用
{"title":"MODERATING ROLE OF NEUROTICISM BETWEEN TOKOPHOBIA AND MENTAL HEALTH AMONG PRIMIGRAVIDAS","authors":"Romana Ijaz, Mussarat Summaira Naz, Jabeen Khan, H. Bibi","doi":"10.35845/kmuj.2022.20898","DOIUrl":"https://doi.org/10.35845/kmuj.2022.20898","url":null,"abstract":"Moderating role of","PeriodicalId":42581,"journal":{"name":"Khyber Medical University Journal-KMUJ","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46455544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-30DOI: 10.35845/kmuj.2022.22729
Zahid Ali, M. Ismail, Muhammad Tariq, Masood Khan, Inayat Rahman
OBJECTIVE: The current meta-analysis was carried out to identify the efficacy and safety of thalidomide in transfusion-dependent β -thalassemia (TDT) patients. METHODS: Six databases: PubMed, EMBASE, Scopus, Cochrane Library, EBSCOhost
{"title":"SAFETY AND EFFICACY OF THALIDOMIDE IN TRANSFUSION-DEPENDENT β-THALASSEMIA: A SYSTEMATIC REVIEW AND META-ANALYSIS","authors":"Zahid Ali, M. Ismail, Muhammad Tariq, Masood Khan, Inayat Rahman","doi":"10.35845/kmuj.2022.22729","DOIUrl":"https://doi.org/10.35845/kmuj.2022.22729","url":null,"abstract":"OBJECTIVE: The current meta-analysis was carried out to identify the efficacy and safety of thalidomide in transfusion-dependent β -thalassemia (TDT) patients. METHODS: Six databases: PubMed, EMBASE, Scopus, Cochrane Library, EBSCOhost","PeriodicalId":42581,"journal":{"name":"Khyber Medical University Journal-KMUJ","volume":"46 ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41276491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-30DOI: 10.35845/kmuj.2022.21702
K. Khan, S. Qureshi
OBJECTIVE: To explore the association between observed complications in patients diagnosed with dengue fever and patients' demographic and clinical characteristics. METHODS: This cross-sectional analysis of data collected from prospective study conducted in a private hospital in Peshawar, Pakistan and comprised data of dengue patients admitted from June 2018 to December 2019. Laboratory parameters and clinical outcomes were studied. STATA 16 was used for data management and analysis. RESULTS: Out of 200 diagnosed patients of Dengue fever, 135 (67.5%) were males and 65 (32.5%) were females. The median age of diagnosis was 36 years and 67.5% were males. Only 6 (3.0%) patients were diagnosed with severe dengue disease. Forty-two (29.0%) patients experienced one or more complication(s). Most common complications observed were coagulopathy (n=16; 8%), dengue shock syndrome (n=15; 7.5%) and sepsis with infection (n=6; 3%). Median (interquartile range-IQR) of platelet count (x10^12/l) was 72.9 (41.1-129.9) and 144.0 (100.4-205.0) in patients with and without complications respectively (p<0.001). Platelet transfusion was done in 27 (13.5%) and folic acid supplementation was given to 171 (85.5%) patients. Median (IQR) duration of hospital stay was 4 (3–6) and 3(2–4) days in patient with and without complications (<0.001). Overall mortality rate was 2.0% (n=4/200). There was a statistical difference in proportion of platelet transfusion, duration of hospital stay (number of day) and survival between those who had complications and those who didn't (p=<0.001). CONCLUSION: Platelet transfusion and duration of hospital stay in the hospital were significantly associated with higher risk of dengue complications.
{"title":"ASSOCIATION BETWEEN DENGUE VIRUS RELATED COMPLICATIONS AND PATIENTS’ DEMOGRAPHIC AND CLINICAL CHARACTERISTICS","authors":"K. Khan, S. Qureshi","doi":"10.35845/kmuj.2022.21702","DOIUrl":"https://doi.org/10.35845/kmuj.2022.21702","url":null,"abstract":"OBJECTIVE: To explore the association between observed complications in patients diagnosed with dengue fever and patients' demographic and clinical characteristics. METHODS: This cross-sectional analysis of data collected from prospective study conducted in a private hospital in Peshawar, Pakistan and comprised data of dengue patients admitted from June 2018 to December 2019. Laboratory parameters and clinical outcomes were studied. STATA 16 was used for data management and analysis. RESULTS: Out of 200 diagnosed patients of Dengue fever, 135 (67.5%) were males and 65 (32.5%) were females. The median age of diagnosis was 36 years and 67.5% were males. Only 6 (3.0%) patients were diagnosed with severe dengue disease. Forty-two (29.0%) patients experienced one or more complication(s). Most common complications observed were coagulopathy (n=16; 8%), dengue shock syndrome (n=15; 7.5%) and sepsis with infection (n=6; 3%). Median (interquartile range-IQR) of platelet count (x10^12/l) was 72.9 (41.1-129.9) and 144.0 (100.4-205.0) in patients with and without complications respectively (p<0.001). Platelet transfusion was done in 27 (13.5%) and folic acid supplementation was given to 171 (85.5%) patients. Median (IQR) duration of hospital stay was 4 (3–6) and 3(2–4) days in patient with and without complications (<0.001). Overall mortality rate was 2.0% (n=4/200). There was a statistical difference in proportion of platelet transfusion, duration of hospital stay (number of day) and survival between those who had complications and those who didn't (p=<0.001). CONCLUSION: Platelet transfusion and duration of hospital stay in the hospital were significantly associated with higher risk of dengue complications.","PeriodicalId":42581,"journal":{"name":"Khyber Medical University Journal-KMUJ","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45308935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-30DOI: 10.35845/kmuj.2022.22406
{"title":"THE HIDDEN VALUE OF CLINICAL PHYSIOLOGY TESTS UTILITY IN MEDICAL PRACTICE FOR A BETTER UNDERSTANDING: A MESSAGE FOR THE DECISION MAKERS","authors":"","doi":"10.35845/kmuj.2022.22406","DOIUrl":"https://doi.org/10.35845/kmuj.2022.22406","url":null,"abstract":"","PeriodicalId":42581,"journal":{"name":"Khyber Medical University Journal-KMUJ","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45892286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.35845/kmuj.2022.20565
J. Ahmed, G. Saqulain, Muhammad Iqbal, Javed Khan, Mobeen Kausar
of 26
26
{"title":"ROLE OF PARENTAL SUSPICION OF HEARING IMPAIRMENT ON AGE OF DIAGNOSIS & INTERVENTION: A PAKISTANI PERSPECTIVE","authors":"J. Ahmed, G. Saqulain, Muhammad Iqbal, Javed Khan, Mobeen Kausar","doi":"10.35845/kmuj.2022.20565","DOIUrl":"https://doi.org/10.35845/kmuj.2022.20565","url":null,"abstract":"of 26","PeriodicalId":42581,"journal":{"name":"Khyber Medical University Journal-KMUJ","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45779069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.35845/kmuj.2022.22432
Maheen Tariq, Wan Nazatul, Raja Shima Shahidan, Azman Awang
the
这个
{"title":"INTERLEUKIN-8 AND INTERLEUKIN-1Α LEVELS IN THE GINGIVAL CREVICULAR FLUID OF PERIODONTITIS PATIENTS AND THEIR CORRELATION WITH PERIODONTAL POCKET DEPTH AND BLEEDING ON PROBING","authors":"Maheen Tariq, Wan Nazatul, Raja Shima Shahidan, Azman Awang","doi":"10.35845/kmuj.2022.22432","DOIUrl":"https://doi.org/10.35845/kmuj.2022.22432","url":null,"abstract":"the","PeriodicalId":42581,"journal":{"name":"Khyber Medical University Journal-KMUJ","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48764613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.35845/kmuj.2022.22066
Tayaba Mazhar, Asma Ambareen, S. Jabeen
OBJECTIVE: To determine the effects of short inter delivery interval (IDI) on mode of delivery in patients with immediate previous one caesarean section (C-Section). METHODS: This is a retrospective chart review of 120 patients treated at Khyber Teaching Hospital, Peshawar, Pakistan from December 2017 to December 2019. Patients of previous one C-Section and with gestational age of >37 weeks were included in this study. Outcome variables were mode of delivery whether operative or vaginal delivery, maternal and fetal complications such as scar dehiscence or scar rupture and fetal distress. RESULTS: Mean age of the patients was 28.9±2 years. IDI was <18 months in 35/120 (29.2%) cases, 18-24 months in 54/120(45%) cases and >24 months in 31/120 (25.8%) cases. Out of 120, 102 (85%) patients underwent trial of labour after C-section (TOLAC). TOLAC was successful in 64 (62.7%) cases. Patient who underwent TOLAC with IDI of <18 months, 5/21 (23.8%) patients delivered vaginally and 16/21 (76.2%) patients had emergency C-Section while those with 18-24 months IDI, 38/51 (74.5%) patients delivered and 13/51 (25.4 %) patients had emergency C-Section. Main indications for emergency C-Section were scar tenderness and maternal tachycardia (n=16; 42.10%) and fetal distress (n=11, 28.9%). There were two cases of interauterine deaths. Uterine scar dehiscence was observed in 14.28% and 2.4% in short and normal IDI respectively. CONCLUSION: Patients with short IDI had high C-section and uterine scar dehiscence rate. IDI of >18 months is recommended to avoid the maternal and fetal morbidity and mortality.
{"title":"EFFECTS OF SHORT INTER-DELIVERY INTERVAL ON MODE OF DELIVERY IN PREVIOUS ONE CAESAREAN SECTION CASES","authors":"Tayaba Mazhar, Asma Ambareen, S. Jabeen","doi":"10.35845/kmuj.2022.22066","DOIUrl":"https://doi.org/10.35845/kmuj.2022.22066","url":null,"abstract":"OBJECTIVE: To determine the effects of short inter delivery interval (IDI) on mode of delivery in patients with immediate previous one caesarean section (C-Section). METHODS: This is a retrospective chart review of 120 patients treated at Khyber Teaching Hospital, Peshawar, Pakistan from December 2017 to December 2019. Patients of previous one C-Section and with gestational age of >37 weeks were included in this study. Outcome variables were mode of delivery whether operative or vaginal delivery, maternal and fetal complications such as scar dehiscence or scar rupture and fetal distress. RESULTS: Mean age of the patients was 28.9±2 years. IDI was <18 months in 35/120 (29.2%) cases, 18-24 months in 54/120(45%) cases and >24 months in 31/120 (25.8%) cases. Out of 120, 102 (85%) patients underwent trial of labour after C-section (TOLAC). TOLAC was successful in 64 (62.7%) cases. Patient who underwent TOLAC with IDI of <18 months, 5/21 (23.8%) patients delivered vaginally and 16/21 (76.2%) patients had emergency C-Section while those with 18-24 months IDI, 38/51 (74.5%) patients delivered and 13/51 (25.4 %) patients had emergency C-Section. Main indications for emergency C-Section were scar tenderness and maternal tachycardia (n=16; 42.10%) and fetal distress (n=11, 28.9%). There were two cases of interauterine deaths. Uterine scar dehiscence was observed in 14.28% and 2.4% in short and normal IDI respectively. CONCLUSION: Patients with short IDI had high C-section and uterine scar dehiscence rate. IDI of >18 months is recommended to avoid the maternal and fetal morbidity and mortality.","PeriodicalId":42581,"journal":{"name":"Khyber Medical University Journal-KMUJ","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48049350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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