{"title":"FDA Approves First Dietary Supplement under New Drug Application with the Indication of Serious or Life-Threatening Illnesses","authors":"Huu S. Tieu, M. Loeffler","doi":"10.4236/pp.2022.1312038","DOIUrl":"https://doi.org/10.4236/pp.2022.1312038","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology & Pharmacy","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123177390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mst. Boby Aktar Bithy, Milon Kumar Ghosh, Ashim Kumar, Md. Rafiqul Islam Khan, M. I. I. Wahed, R. Barman
{"title":"Role of Polyethylene Glycol and Silica for Dissolution Enhancement of Cefuroxime Axetil: <i>In-Vitro</i> Performance Evaluation and Characterization","authors":"Mst. Boby Aktar Bithy, Milon Kumar Ghosh, Ashim Kumar, Md. Rafiqul Islam Khan, M. I. I. Wahed, R. Barman","doi":"10.4236/pp.2023.145012","DOIUrl":"https://doi.org/10.4236/pp.2023.145012","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122886084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating the Effects of Crystallinity on Drug Release Behaviour in Itraconazole- or Miconazole-Loaded PLGA Microparticles Prepared Using a Co-Grinding Method","authors":"Kazuhiro Matsuura, Honami Kojima, Miyako Yoshida, Takahiro Uchida","doi":"10.4236/pp.2023.149022","DOIUrl":"https://doi.org/10.4236/pp.2023.149022","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129401869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Identified Analytical Profile for Microelements, Trace Metals, Amino Acids and Screening of Anti-Diabetic Activity from Flower and Leaf Extracts of <i>Moringa oleifera</i> in Streptozotocin (STZ)-Induced Diabetic Rats","authors":"Hemalatha Kamurthy, Sirajunisa Talath","doi":"10.4236/pp.2022.136012","DOIUrl":"https://doi.org/10.4236/pp.2022.136012","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"15 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120950039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Sarkar, Sozoni Khatun, T. Enam, M. Jahan, A. Sarker, Nilay Saha, Md. Ariful Islam, Shantanu Saha Sani
Diabetes is a metabolic illness defined by hyperglycemia that affects 10% of the world’s population. Diabetic complications such as blindness, kidney failure, and heart failure can develop if left untreated and are made worse by oxidative stress. Oxidative stress contributes to the rise of diabetic complications, particularly type-2 diabetes. In the blood vessels of diabetic individuals, it causes endothelial dysfunction. Diabetes is one of the leading causes of death worldwide. Nowadays, it is alarming that the number of diabetic patients is increasing dramatically. There are plenty of anti-diabetic drugs available on the market, but they possess several adverse effects and do not completely cure diabetes. It has now become a financial burden on patients, their families, and society as well. Medicinal plants have gained popularity in developed and developing countries over the last two decades because of their vast natural sources and lack of harmful effects compared to modern allo-pathic medications. According to the World Health Organization, traditional medicines, which are mostly manufactured from plants, are still used by 80% of the population in developing countries for the management and curing of ti-diabetic and antioxidant capabilities so that the researchers can develop newer anti-diabetic medications with minimal side effects to treat metabolic dysfunction, diabetic complications, and oxidative stress more effectively.
{"title":"Promising Actions of Certain Medicinal Plants of Bangladesh against Diabetes and Oxidative Stress: A Review","authors":"A. Sarkar, Sozoni Khatun, T. Enam, M. Jahan, A. Sarker, Nilay Saha, Md. Ariful Islam, Shantanu Saha Sani","doi":"10.4236/pp.2022.1310030","DOIUrl":"https://doi.org/10.4236/pp.2022.1310030","url":null,"abstract":"Diabetes is a metabolic illness defined by hyperglycemia that affects 10% of the world’s population. Diabetic complications such as blindness, kidney failure, and heart failure can develop if left untreated and are made worse by oxidative stress. Oxidative stress contributes to the rise of diabetic complications, particularly type-2 diabetes. In the blood vessels of diabetic individuals, it causes endothelial dysfunction. Diabetes is one of the leading causes of death worldwide. Nowadays, it is alarming that the number of diabetic patients is increasing dramatically. There are plenty of anti-diabetic drugs available on the market, but they possess several adverse effects and do not completely cure diabetes. It has now become a financial burden on patients, their families, and society as well. Medicinal plants have gained popularity in developed and developing countries over the last two decades because of their vast natural sources and lack of harmful effects compared to modern allo-pathic medications. According to the World Health Organization, traditional medicines, which are mostly manufactured from plants, are still used by 80% of the population in developing countries for the management and curing of ti-diabetic and antioxidant capabilities so that the researchers can develop newer anti-diabetic medications with minimal side effects to treat metabolic dysfunction, diabetic complications, and oxidative stress more effectively.","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127024044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Centrum Multivitamin Content Analysis—Over the Counter—OTC Medicine on Facebook","authors":"Euripedes Fernandes de Oliveira J.","doi":"10.4236/pp.2022.1311037","DOIUrl":"https://doi.org/10.4236/pp.2022.1311037","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127884526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pramipexole in Treatment Resistant Depression: A Case Review","authors":"N. Abdallah, J. Kahn","doi":"10.4236/pp.2023.147016","DOIUrl":"https://doi.org/10.4236/pp.2023.147016","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129057967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aminata P. Nacoulma, Gontili Reine Elodie Karambiri, N. R. Meda, M. J. Bangou, Moussa Ouedraogo, D. Ouédraogo
Joint pain is a real public health problem. According to recent studies, it is increasingly common in sub-Saharan Africa and represents a cause of greater loss of working days than accidents, heart disease and infections. The aim of this study was to study the pharmacochemical and therapeutic evidence of ten (10) plants used in the management of joint pain by traditional health practitioners in Ouagadougou. We conducted a meta-analysis of the data from December 2018 to September 2019. The anti-inflammatory activity of the ten (10) plants retained the maximum consensus internationally. Trichilia emetica Vahl (35.25%), Guiera senegalensis J.F.G.mel. (31%), Calotropis procera (Ait) Ait.F. (28.29%) and Crescientia cujete L. (25.12%) had more than 25% internationally reliability for their effects on joint pain. The structural analogy between conventional drugs and the molecules found in these plants has been confirmed. Additional studies should be carried out in order to improve and secure the use of these plants, which represent a prominent option in the therapeutic offer. identified in Trichilia emetica Vahl, Guiera senegalensis J.F.G.mel., Calotropis procera (Ait) Ait.F. These observations strengthen scientific basis for the use of Trichilia emetica Vahl, Guiera senegalensis J.F.G.mel., Calotropis procera (Ait) Ait.F. and Crescientia cujete L. in inflammatory joint pain treatment. The subsequent evaluation of therapeutic equivalences will allow the devel-opment of plant-based phytomedicines, standardized in therapeutic equivalent of modern treatments per gram of dry plant material. Evaluation of QSAR of plant compounds as indolic alkaloids and modified triterpenic compounds with potent anti-inflammatory properties could give models for drug design and dis-covery in the area of new therapies development.
{"title":"Contribution to the Valorization of Plants Used in the Management of Rheumatic Diseases in Burkina Faso","authors":"Aminata P. Nacoulma, Gontili Reine Elodie Karambiri, N. R. Meda, M. J. Bangou, Moussa Ouedraogo, D. Ouédraogo","doi":"10.4236/pp.2022.133006","DOIUrl":"https://doi.org/10.4236/pp.2022.133006","url":null,"abstract":"Joint pain is a real public health problem. According to recent studies, it is increasingly common in sub-Saharan Africa and represents a cause of greater loss of working days than accidents, heart disease and infections. The aim of this study was to study the pharmacochemical and therapeutic evidence of ten (10) plants used in the management of joint pain by traditional health practitioners in Ouagadougou. We conducted a meta-analysis of the data from December 2018 to September 2019. The anti-inflammatory activity of the ten (10) plants retained the maximum consensus internationally. Trichilia emetica Vahl (35.25%), Guiera senegalensis J.F.G.mel. (31%), Calotropis procera (Ait) Ait.F. (28.29%) and Crescientia cujete L. (25.12%) had more than 25% internationally reliability for their effects on joint pain. The structural analogy between conventional drugs and the molecules found in these plants has been confirmed. Additional studies should be carried out in order to improve and secure the use of these plants, which represent a prominent option in the therapeutic offer. identified in Trichilia emetica Vahl, Guiera senegalensis J.F.G.mel., Calotropis procera (Ait) Ait.F. These observations strengthen scientific basis for the use of Trichilia emetica Vahl, Guiera senegalensis J.F.G.mel., Calotropis procera (Ait) Ait.F. and Crescientia cujete L. in inflammatory joint pain treatment. The subsequent evaluation of therapeutic equivalences will allow the devel-opment of plant-based phytomedicines, standardized in therapeutic equivalent of modern treatments per gram of dry plant material. Evaluation of QSAR of plant compounds as indolic alkaloids and modified triterpenic compounds with potent anti-inflammatory properties could give models for drug design and dis-covery in the area of new therapies development.","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116234768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Allabi, Areine Gracidie Agbo, Bawa Boya, Steward Mudenda
{"title":"Antimicrobial Stewardship: Knowledge and Attitudes of Pharmacy Staff on Antibiotic Dispensing Patterns, Use and Resistance in Benin","authors":"A. Allabi, Areine Gracidie Agbo, Bawa Boya, Steward Mudenda","doi":"10.4236/pp.2023.146014","DOIUrl":"https://doi.org/10.4236/pp.2023.146014","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123346385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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