{"title":"The Use of Intramuscular Praziquantel in South-African Ruminants against Cestode Parasites. A First Pilot Study","authors":"C. Vermaak, C. Boshoff","doi":"10.4236/pp.2022.1310031","DOIUrl":"https://doi.org/10.4236/pp.2022.1310031","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology & Pharmacy","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121385522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Steward Mudenda, M. Chomba, Billy Chabalenge, C. Hikaambo, M. Banda, V. Daka, A. Zulu, Abraham Mukesela, Maxwell Kasonde, P. Lukonde, E. Chikatula, L. Matowe, R. Mutati, T. L. Muungo, Tobela Mudenda, Shafiq Mohamed, S. Matafwali
{"title":"Antibiotic Prescribing Patterns in Adult Patients According to the WHO AWaRe Classification: A Multi-Facility Cross-Sectional Study in Primary Healthcare Hospitals in Lusaka, Zambia","authors":"Steward Mudenda, M. Chomba, Billy Chabalenge, C. Hikaambo, M. Banda, V. Daka, A. Zulu, Abraham Mukesela, Maxwell Kasonde, P. Lukonde, E. Chikatula, L. Matowe, R. Mutati, T. L. Muungo, Tobela Mudenda, Shafiq Mohamed, S. Matafwali","doi":"10.4236/pp.2022.1310029","DOIUrl":"https://doi.org/10.4236/pp.2022.1310029","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology & Pharmacy","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116336437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. L. Da, Basile Tindano, Géneviève Zabre, Karim Sakira, B. Bayala, Raymond G Belemtougri, P. Horlait
{"title":"Effects of <i>Sarcocephalus latifolius</i> Fruits Extract on Paracetamol-Induced Liver Damage in Wistar Rats","authors":"F. L. Da, Basile Tindano, Géneviève Zabre, Karim Sakira, B. Bayala, Raymond G Belemtougri, P. Horlait","doi":"10.4236/pp.2023.144009","DOIUrl":"https://doi.org/10.4236/pp.2023.144009","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125133041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rainatou Boly, Abdoul Gilchrist Laurent Boly, W. Belem-Kabré, Kadiatou Tata Traoré, B. Kaboré, Ollo Youl, Latifatou Sawadogo, Mathieu Nitiema, Moumouni Koala, N. Ouedraogo, Estella Noëla Hoho Youl, M. Traoré-Coulibaly
Opilia amentacea (Opiliaceae) is a woody plant with multiple medicinal claimed effects. The present study aimed to assess the anti-inflammatory and
蛇麻属(蛇麻科)是一种具有多种药用功效的木本植物。本研究旨在评估抗炎和
{"title":"Anti-Inflammatory and Antioxidant Properties of the Aqueous Extracts of the Leaves of <i>Opilia amentacea</i> (Opiliaceae)","authors":"Rainatou Boly, Abdoul Gilchrist Laurent Boly, W. Belem-Kabré, Kadiatou Tata Traoré, B. Kaboré, Ollo Youl, Latifatou Sawadogo, Mathieu Nitiema, Moumouni Koala, N. Ouedraogo, Estella Noëla Hoho Youl, M. Traoré-Coulibaly","doi":"10.4236/pp.2023.149021","DOIUrl":"https://doi.org/10.4236/pp.2023.149021","url":null,"abstract":"Opilia amentacea (Opiliaceae) is a woody plant with multiple medicinal claimed effects. The present study aimed to assess the anti-inflammatory and","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125152924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Raffa, Joseph V. Pergolizzi Jr., T. Miller, Daniel Motto
{"title":"<i>Commentary</i>: Unexpected Novel Chemical Weapon Agents Designed by Innocuous Drug-Development AI (Artificial Intelligence) Algorithm","authors":"R. Raffa, Joseph V. Pergolizzi Jr., T. Miller, Daniel Motto","doi":"10.4236/pp.2022.137018","DOIUrl":"https://doi.org/10.4236/pp.2022.137018","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125376128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shin-Hee Kim, Hyunjin Kim, Semi Kim, Ju‐Seop Kang, Y. Koo, Sang Hun Lee, Dong-Hyun Paik
Vitamin C and taurine (TR) are well known as active components for fatigue recovery. However, the mechanism of the anti-fatigue effects of vitamin C and TR is still unclear. Our study was designed to evaluate the anti-fatigue activities of vitamin C and TR in an animal test for fatigue and to compare the activities between vitamin C and TR. Materials and Methods: Vitamin C, TR or their combination were orally administrated to mice once daily for 15 days, and then metabolic activities such as blood glucose, triglyceride (TG), lactate, and lactate dehydrogenase (LDH) as well as antioxidant activities such as malondialdehyde (MDA) and superoxide dismutase (SOD) were determined (evaluated) after forced swimming test (FST). Results: Compared with the control group, C100, C200, and T50 showed a tendency to decrease mobility in FST. Moreover, TG (C100, C200, T200), LDH (C200), lactic acid (C100) and MDA (C50, C100, C200) levels were inhibited by vitamin C and TR. Con-clusions: These results suggest that vitamin C and TR have anti-fatigue activities in mice, with vitamin C providing a stronger effect.
{"title":"A Comparative Study of Antifatigue Effects of Taurine and Vitamin C on Chronic Fatigue Syndrome","authors":"Shin-Hee Kim, Hyunjin Kim, Semi Kim, Ju‐Seop Kang, Y. Koo, Sang Hun Lee, Dong-Hyun Paik","doi":"10.4236/pp.2022.138023","DOIUrl":"https://doi.org/10.4236/pp.2022.138023","url":null,"abstract":"Vitamin C and taurine (TR) are well known as active components for fatigue recovery. However, the mechanism of the anti-fatigue effects of vitamin C and TR is still unclear. Our study was designed to evaluate the anti-fatigue activities of vitamin C and TR in an animal test for fatigue and to compare the activities between vitamin C and TR. Materials and Methods: Vitamin C, TR or their combination were orally administrated to mice once daily for 15 days, and then metabolic activities such as blood glucose, triglyceride (TG), lactate, and lactate dehydrogenase (LDH) as well as antioxidant activities such as malondialdehyde (MDA) and superoxide dismutase (SOD) were determined (evaluated) after forced swimming test (FST). Results: Compared with the control group, C100, C200, and T50 showed a tendency to decrease mobility in FST. Moreover, TG (C100, C200, T200), LDH (C200), lactic acid (C100) and MDA (C50, C100, C200) levels were inhibited by vitamin C and TR. Con-clusions: These results suggest that vitamin C and TR have anti-fatigue activities in mice, with vitamin C providing a stronger effect.","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126711151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oxazolidinones Antibiotics, Chemistry, Applications and Role in COVID-19 Treatment","authors":"Alaa Saleh Mahdi, B. Alani, I. T. Ibrahim","doi":"10.4236/pp.2023.141002","DOIUrl":"https://doi.org/10.4236/pp.2023.141002","url":null,"abstract":"","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134516082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hanna J. Tillman, Juliana Gassmann, Shelby Stensgard, Alex Nguyen, Nicholas Tieu, Markus Melbardis, Hayden Gharibyar
Inflammatory diseases such as rheumatoid arthritis (RA) can lead to chronic pain and joint deformity. First line treatment includes disease-modifying antirheumatic drugs (DMARDs) to slow disease progression, but RA patients are often left with debilitating symptoms. This article explores alternative topical and naturally based options to treat RA symptoms, with supporting evidence for their use. Considered options include Aloe vera, Perillyl Alcohol (POH), Aleurites moluccana, Calendula officinalis extract (quercetin), Achyranthes species, Guizhi Shaoyao Zhimu, Curcumin (turmeric), Wutou, Radix paeoniae extract (Paeoniflorin), Tripterygium wilfordii Hook F (TWHF), Capsaicin, Cannabinoids (CBD), and Berberine. Many of these products show promising data for supplemental treatment of RA through various mechanisms, with CBD and TWHF having the most robust evidence supporting their use.
{"title":"Pharmacist’s Evaluation of Natural Ingredients in Topical Products for Rheumatoid Arthritis","authors":"Hanna J. Tillman, Juliana Gassmann, Shelby Stensgard, Alex Nguyen, Nicholas Tieu, Markus Melbardis, Hayden Gharibyar","doi":"10.4236/pp.2022.138021","DOIUrl":"https://doi.org/10.4236/pp.2022.138021","url":null,"abstract":"Inflammatory diseases such as rheumatoid arthritis (RA) can lead to chronic pain and joint deformity. First line treatment includes disease-modifying antirheumatic drugs (DMARDs) to slow disease progression, but RA patients are often left with debilitating symptoms. This article explores alternative topical and naturally based options to treat RA symptoms, with supporting evidence for their use. Considered options include Aloe vera, Perillyl Alcohol (POH), Aleurites moluccana, Calendula officinalis extract (quercetin), Achyranthes species, Guizhi Shaoyao Zhimu, Curcumin (turmeric), Wutou, Radix paeoniae extract (Paeoniflorin), Tripterygium wilfordii Hook F (TWHF), Capsaicin, Cannabinoids (CBD), and Berberine. Many of these products show promising data for supplemental treatment of RA through various mechanisms, with CBD and TWHF having the most robust evidence supporting their use.","PeriodicalId":432281,"journal":{"name":"Pharmacology &amp; Pharmacy","volume":"103 3 Pt 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131635118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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