Introductıon: There are several indirect and non-invasive techniques measuring blood pressure. The most popular non-invasive technique for routine examinations and monitoring is auscultation of Korotkoff sounds. We compared non-invasive and invasive systolic and diastolic blood pressure measurements in this study. Methods: 46 adult patients to be operated on for any reason in Bulent Ecevit University Hospital were included in the study. The study patients’ age, gender, height, weight and body mass index were recorded. Blood pressure was directly measured from radial arter and indirectly measured from brachial artery via a automated oscillometric device. Invasive and non-invasive blood pressure and pulse measurements were performed simultaneously. Median systolic and diastolic blood pressures obtained from all patients by both methods. Results: Mean non-invasive systolic blood pressure was 114,6±18,72 mmHg, mean invasive systolic blood pressure was 116,1±18,08 mmHg, mean non-invasive diastolic blood pressure was 69,42±11,31 mmHg, mean invasive diastolic blood pressure was 63,81±12,26 mmHg in the study patients. The difference between mean invasive and non-invasive systolic blood pressure wasn’t significant (p=0,28) but the difference between mean invasive and noninvasive diastolic blood pressure was statistically significant (p<0,001).
{"title":"There is No Correlation Between Non Invasive Diastolic Blood Pressure and Invasive Diastolic Blood Pressure","authors":"I. Yildirim","doi":"10.5505/AOT.2021.14880","DOIUrl":"https://doi.org/10.5505/AOT.2021.14880","url":null,"abstract":"Introductıon: There are several indirect and non-invasive techniques measuring blood pressure. The most popular non-invasive technique for routine examinations and monitoring is auscultation of Korotkoff sounds. We compared non-invasive and invasive systolic and diastolic blood pressure measurements in this study. Methods: 46 adult patients to be operated on for any reason in Bulent Ecevit University Hospital were included in the study. The study patients’ age, gender, height, weight and body mass index were recorded. Blood pressure was directly measured from radial arter and indirectly measured from brachial artery via a automated oscillometric device. Invasive and non-invasive blood pressure and pulse measurements were performed simultaneously. Median systolic and diastolic blood pressures obtained from all patients by both methods. Results: Mean non-invasive systolic blood pressure was 114,6±18,72 mmHg, mean invasive systolic blood pressure was 116,1±18,08 mmHg, mean non-invasive diastolic blood pressure was 69,42±11,31 mmHg, mean invasive diastolic blood pressure was 63,81±12,26 mmHg in the study patients. The difference between mean invasive and non-invasive systolic blood pressure wasn’t significant (p=0,28) but the difference between mean invasive and noninvasive diastolic blood pressure was statistically significant (p<0,001).","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125894879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arzu Hushmand Arya, Kevser Esmeray Çifci, M. Nazlı
{"title":"Contribution of Diffusion-Weighted Imaging and Ultrasound Elastography to the Diagnosis of Breast Cancer","authors":"Arzu Hushmand Arya, Kevser Esmeray Çifci, M. Nazlı","doi":"10.5505/aot.2022.53496","DOIUrl":"https://doi.org/10.5505/aot.2022.53496","url":null,"abstract":"","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"437 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126123338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Infantile hemangioendothelioma is a rare benign vascular tumor of the liver which generally presenting an abdominal mass or hepatomegaly. Although it is considered a benign lesion it can cause clinically very serious symptoms. Therefore, correct diagnosis is very important for proper treatment. The case of a 6-month-old female patient with multiple hepatic infantile hemangioendotheliomas is reported with ultrasonographic and CT
{"title":"Multiple Infantile Hepatic Hemangioendothelioma: Doppler Ultrasonography and CT findings of a case","authors":"C. Imamoğlu, Y. Mohamed, A. Yıldız, A. Mohamed","doi":"10.5505/AOT.2019.82335","DOIUrl":"https://doi.org/10.5505/AOT.2019.82335","url":null,"abstract":"Infantile hemangioendothelioma is a rare benign vascular tumor of the liver which generally presenting an abdominal mass or hepatomegaly. Although it is considered a benign lesion it can cause clinically very serious symptoms. Therefore, correct diagnosis is very important for proper treatment. The case of a 6-month-old female patient with multiple hepatic infantile hemangioendotheliomas is reported with ultrasonographic and CT","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129468618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
INTRODUCTION: This study was planned with the aim of assessing general characteristics, performance status, applied treatments and survival rates of patients diagnosed with metastatic colorectal cancer (CRC) over the age of 65 years. METHODS: This study was conducted between October 2010 and October 2014 at Dr. A.Y. Ankara Oncology Training and Research Hospital, Department of Medical Oncology Clinic. The files in the archives were scanned retrospectively and 139 patients diagnosed with colorectal cancer, who were 65 years or older in the metastatic stage were identified. RESULTS: The median age of the patients was 73 (65-87). When evaluated according to age range, 81 (58.3%) of the patients were aged between 65-74, 53 (38.1%) were between 75-84 years and 5 (3.6%) were over 85 years old. The majority (57%) were male. Overall survival was 12.09 months (% 95 GA; 9.5-14.64). According to age range, median OS was 16.39 months between 65-74 years, 12.87 months (% 95 GA; 9.2-16.5 ) (p: 0.906) over 75 years. DISCUSSION and CONCLUSION: Advanced age should not be considered as a negative factor in planning treatment. After diagnosis and staging, multidisciplinary approach and treatment options should be applied considering personal wishes of the patient. Close and careful follow-up should be performed for toxicities that may be encountered, and supportive care should be applied when necessary.
{"title":"Retrospective Evaluation of Sixty Five Year And Older Patients with Metastatic Colorectal Cancer","authors":"H. Yeşil Çınkır, B. Öksüzoğlu","doi":"10.5505/aot.2019.57441","DOIUrl":"https://doi.org/10.5505/aot.2019.57441","url":null,"abstract":"INTRODUCTION: This study was planned with the aim of assessing general characteristics, performance status, applied treatments and survival rates of patients diagnosed with metastatic colorectal cancer (CRC) over the age of 65 years. METHODS: This study was conducted between October 2010 and October 2014 at Dr. A.Y. Ankara Oncology Training and Research Hospital, Department of Medical Oncology Clinic. The files in the archives were scanned retrospectively and 139 patients diagnosed with colorectal cancer, who were 65 years or older in the metastatic stage were identified. RESULTS: The median age of the patients was 73 (65-87). When evaluated according to age range, 81 (58.3%) of the patients were aged between 65-74, 53 (38.1%) were between 75-84 years and 5 (3.6%) were over 85 years old. The majority (57%) were male. Overall survival was 12.09 months (% 95 GA; 9.5-14.64). According to age range, median OS was 16.39 months between 65-74 years, 12.87 months (% 95 GA; 9.2-16.5 ) (p: 0.906) over 75 years. DISCUSSION and CONCLUSION: Advanced age should not be considered as a negative factor in planning treatment. After diagnosis and staging, multidisciplinary approach and treatment options should be applied considering personal wishes of the patient. Close and careful follow-up should be performed for toxicities that may be encountered, and supportive care should be applied when necessary.","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124306743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
INTRODUCTION: The ability to meet daily needs decreases with advancing age. As a result of both the disease and the treatments applied to the elderly patients who are followed up with the diagnosis of cancer, daily living activities are affected. The aim of this study was to evaluate the factors affecting activities of daily living in geriatric cancer patients. METHODS: In this study, patients aged 65 years and older who were followed up in the Medical Oncology outpatient clinic were evaluated. In addition to demographic and disease characteristics, a questionnaire including Lawton–Brody Instrumental Activities of Daily Living Scale (IADL) was applied. RESULTS: 129 patients aged 65 years and older were evaluated in the study. When the IADL scores were evaluated; it was found that IADL scores were higher in those under 75 years, those who do not have any children, and those with an education equal to or greater than primary school level. In multivariate analysis; low education level was associated with low IADL scores (OR: 5.4(%95 CI 1.1-26.2), p= 0.035). CONCLUSION: Evaluation of IADL is precious for determining the palliation or rehabilitation needs and cognitive/ physical functionality. Especially patients with low education level should be evaluated with IADL and patient under risk should be further evaluated with multidimensional geriatric assessment tools.
随着年龄的增长，满足日常需求的能力会下降。由于疾病和对被诊断为癌症的老年患者进行的治疗，日常生活活动受到影响。本研究的目的是评估影响老年癌症患者日常生活活动的因素。方法:在本研究中，对在肿瘤内科门诊随访的65岁及以上患者进行评估。除人口统计学和疾病特征外，还采用了包括Lawton-Brody日常生活工具活动量表(IADL)在内的问卷。结果:129例65岁及以上患者纳入研究。评估IADL评分时;研究发现，75岁以下、没有孩子以及受教育程度等于或高于小学水平的人的IADL得分更高。在多元分析中;低教育水平与低IADL评分相关(OR: 5.4(%95 CI 1.1-26.2)， p= 0.035)。结论:IADL的评估对于确定姑息或康复需求和认知/身体功能是宝贵的。尤其对受教育程度较低的患者应采用IADL进行评估，对有风险的患者应进一步采用多维老年评估工具进行评估。
{"title":"Factors Associated with Activities Of Daily Living In Geriatric Patients With Cancer","authors":"A. Alkan","doi":"10.5505/aot.2019.83702","DOIUrl":"https://doi.org/10.5505/aot.2019.83702","url":null,"abstract":"INTRODUCTION: The ability to meet daily needs decreases with advancing age. As a result of both the disease and the treatments applied to the elderly patients who are followed up with the diagnosis of cancer, daily living activities are affected. The aim of this study was to evaluate the factors affecting activities of daily living in geriatric cancer patients. METHODS: In this study, patients aged 65 years and older who were followed up in the Medical Oncology outpatient clinic were evaluated. In addition to demographic and disease characteristics, a questionnaire including Lawton–Brody Instrumental Activities of Daily Living Scale (IADL) was applied. RESULTS: 129 patients aged 65 years and older were evaluated in the study. When the IADL scores were evaluated; it was found that IADL scores were higher in those under 75 years, those who do not have any children, and those with an education equal to or greater than primary school level. In multivariate analysis; low education level was associated with low IADL scores (OR: 5.4(%95 CI 1.1-26.2), p= 0.035). CONCLUSION: Evaluation of IADL is precious for determining the palliation or rehabilitation needs and cognitive/ physical functionality. Especially patients with low education level should be evaluated with IADL and patient under risk should be further evaluated with multidimensional geriatric assessment tools.","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115383219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Mert, A. Merdin, Bahar Uncu Ulu, M. Dal, M. Kızıl Çakar, G. İskender, Sabahat Çeken, T. Yiğenoğlu, F. Altuntaş, M. Ertek
Introduction: It is controversial that cytomegalovirus (CMV) replication is a cause of graft-versus-host disease (GVHD). The aim of this study is to evaluate whether CMV replication causes acute GVHD development or not. Materials and methods: The study is retrospective. Patients diagnosed with acute GVHD with a prior history of allogeneic hematopoietic cell transplantation (allo-HCT) were included in the study. All the included patients were followed-up in the bone marrow transplantation unit between 01/01/201310/31/2019. As the control group, patients without a history of acute GVHD after allo-HCT were included. The data of patients with acute GVHD after allo-HCT and patients with out known acute GVHD were compared. Results: Fifty nine patients with acute GVHD and 178 patients without acute GVHD after allo-HCT were included in the study. Sixteen of the patients with acute GVHD were female and 43 were male. Sixty two of the patients without acute GVHD were female and 116 were male. The average CMVDNA level was found as 1871.0 [821.0-16720.0] copies/ml in patients who had CMV replication in the acute GVHD group. On the other hand, the average of CMV-DNA level was found as 1607.5 [601.0119181.0] copies/ml in the non-acute GVHD group. There was no statistically significant difference between the two groups. Discussion: CMV replication does not seem to contribute to acute GVHD development after allo-HCT. Suppression of CMV replication may not prevent acute GVHD development.
{"title":"Evaluation of the relationship between cytomegalovirus replication and acute graft-versus-host disease in patients with allogeneic hematopoietic stem cell transplantation","authors":"D. Mert, A. Merdin, Bahar Uncu Ulu, M. Dal, M. Kızıl Çakar, G. İskender, Sabahat Çeken, T. Yiğenoğlu, F. Altuntaş, M. Ertek","doi":"10.5505/aot.2021.30643","DOIUrl":"https://doi.org/10.5505/aot.2021.30643","url":null,"abstract":"Introduction: It is controversial that cytomegalovirus (CMV) replication is a cause of graft-versus-host disease (GVHD). The aim of this study is to evaluate whether CMV replication causes acute GVHD development or not. Materials and methods: The study is retrospective. Patients diagnosed with acute GVHD with a prior history of allogeneic hematopoietic cell transplantation (allo-HCT) were included in the study. All the included patients were followed-up in the bone marrow transplantation unit between 01/01/201310/31/2019. As the control group, patients without a history of acute GVHD after allo-HCT were included. The data of patients with acute GVHD after allo-HCT and patients with out known acute GVHD were compared. Results: Fifty nine patients with acute GVHD and 178 patients without acute GVHD after allo-HCT were included in the study. Sixteen of the patients with acute GVHD were female and 43 were male. Sixty two of the patients without acute GVHD were female and 116 were male. The average CMVDNA level was found as 1871.0 [821.0-16720.0] copies/ml in patients who had CMV replication in the acute GVHD group. On the other hand, the average of CMV-DNA level was found as 1607.5 [601.0119181.0] copies/ml in the non-acute GVHD group. There was no statistically significant difference between the two groups. Discussion: CMV replication does not seem to contribute to acute GVHD development after allo-HCT. Suppression of CMV replication may not prevent acute GVHD development.","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"257 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132034660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Bilgetekin, E. Esin, F. Başal, U. Demirci, B. Öksüzoğlu
INTRODUCTION: Ovarian cancer is the fifth most common cancer in women and ranks first among the causes of death due to gynecological cancers. In our study, we aimed to evaluate the recurrence status, survival outcomes and treatment-related side effects of patients treated for ovarian cancer retrospectively. METHODS: The study is performed at Dr.Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital. In this study, 160 patients with ovarian cancer who were followed up for diagnosis and treatment between January 2010 and January 2020 were analyzed retrospectively. The cases were analyzed according to the average age, histopathological types of the ovarian cancer, the stage at the time of diagnosis, the side effects associated with the chemotherapy, the progression-free survival (PFS) and overall survival (OS) rates.Log-Rank test was used to determine survival times. RESULTS: The median age of patients included in the study is 61 ± 11 (50-72). Serous epithelial ovarian cancer was the most common (80.6%) according to histopathological subgroups. When the stage distribution at the time of diagnosis was examined, it was seen that the cases were mostly diagnosed in Stage III. While the most common side effect associated with chemotherapy was alopecia (100%), the incidence of side effects other than alopecia was 51.2%. Recurrence was detected in 48.8% of the cases, and median progression-free survival was 19.1 months, and overall survival was 89.9 months in the whole group.. Overall survival was significantly low in cases with dose reduction (p <0.05).
{"title":"Changes in Ovarian Cancer Prognosis, Ten Years Single Center Experience","authors":"I. Bilgetekin, E. Esin, F. Başal, U. Demirci, B. Öksüzoğlu","doi":"10.5505/AOT.2020.57689","DOIUrl":"https://doi.org/10.5505/AOT.2020.57689","url":null,"abstract":"INTRODUCTION: Ovarian cancer is the fifth most common cancer in women and ranks first among the causes of death due to gynecological cancers. In our study, we aimed to evaluate the recurrence status, survival outcomes and treatment-related side effects of patients treated for ovarian cancer retrospectively. METHODS: The study is performed at Dr.Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital. In this study, 160 patients with ovarian cancer who were followed up for diagnosis and treatment between January 2010 and January 2020 were analyzed retrospectively. The cases were analyzed according to the average age, histopathological types of the ovarian cancer, the stage at the time of diagnosis, the side effects associated with the chemotherapy, the progression-free survival (PFS) and overall survival (OS) rates.Log-Rank test was used to determine survival times. RESULTS: The median age of patients included in the study is 61 ± 11 (50-72). Serous epithelial ovarian cancer was the most common (80.6%) according to histopathological subgroups. When the stage distribution at the time of diagnosis was examined, it was seen that the cases were mostly diagnosed in Stage III. While the most common side effect associated with chemotherapy was alopecia (100%), the incidence of side effects other than alopecia was 51.2%. Recurrence was detected in 48.8% of the cases, and median progression-free survival was 19.1 months, and overall survival was 89.9 months in the whole group.. Overall survival was significantly low in cases with dose reduction (p <0.05).","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124021446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Öztürk, B. Ince, Y. Karakoç, A. Yapar, Yusuf İkbal Erdoğdu, B. Ş. Güngör
INTRODUCTION: It is aimed that a retrospective analysis of 122 patients who were diagnosed with osteosarcoma and underwent surgical treatment between January 2002 and January 2015 at the Orthopedics and Traumatology Clinic of our Hospital. METHODS: Total of 122 patients (81 males, 41 females) were included in the study. All data were retrospectively and completely evaluated, 95,9% of the patients were operated, 72,7% of these patients, had limb salvage surgery and 27,3% had amputation. RESULTS: The mean age was 23.9 years (range 7-82 years), 50% of the patients were between 11 and 20 years of age and 66.3% of them were located in the knee (50.8% distal femur and 15.5% proximal tibia). At the time of diagnosis, 59% of cases were found to be Enneking Stage 2B. The most common tumor type was conventional osteosarcoma. DISCUSSION: When we examined the cases of osteosarcoma which diagnosed in our hospital, the distribution and features of tumor was similar to other cases that is in other hospitals in our country and the world literature.
{"title":"Evaluation Of Demographic And Clinicopathological Characteristics Of Osteosarcoma Patients","authors":"R. Öztürk, B. Ince, Y. Karakoç, A. Yapar, Yusuf İkbal Erdoğdu, B. Ş. Güngör","doi":"10.5505/aot.2019.60234","DOIUrl":"https://doi.org/10.5505/aot.2019.60234","url":null,"abstract":"INTRODUCTION: It is aimed that a retrospective analysis of 122 patients who were diagnosed with osteosarcoma and underwent surgical treatment between January 2002 and January 2015 at the Orthopedics and Traumatology Clinic of our Hospital. METHODS: Total of 122 patients (81 males, 41 females) were included in the study. All data were retrospectively and completely evaluated, 95,9% of the patients were operated, 72,7% of these patients, had limb salvage surgery and 27,3% had amputation. RESULTS: The mean age was 23.9 years (range 7-82 years), 50% of the patients were between 11 and 20 years of age and 66.3% of them were located in the knee (50.8% distal femur and 15.5% proximal tibia). At the time of diagnosis, 59% of cases were found to be Enneking Stage 2B. The most common tumor type was conventional osteosarcoma. DISCUSSION: When we examined the cases of osteosarcoma which diagnosed in our hospital, the distribution and features of tumor was similar to other cases that is in other hospitals in our country and the world literature.","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122074033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Sönmez, M. Keske, Fatih Demir, N. Hamidi, M. Karadağ
INTRODUCTION: Transrectal ultrasound-guided prostate biopsy (TRUS-B) is the gold standard method used to diagnose prostate cancer. However, how many samples should be taken in TRUS-B procedure is still controversial. The aim of this study is to compare the cancer detection rates of standard 10-core and 12-core TRUS-B procedures. METHODS: Patients who underwent 10-core (Group-1) or 12-core (Group-2) TRUS-B operations were included in this retrospective study for prostate specific antigen (PSA) elevation or suspicious digital examination findings. Patients with PSA>20 ng/ml and a history of negative biopsy were excluded from the study. In addition to cancer detection rates of groups, demographic and clinical data such as age, body mass index (BMI), serum PSA ratios and prostate volume were compared. RESULTS: A total of 208 patients were included in the study (Group-1: 98, Group-2: 110). The rate of cancer detection was 43.2% in all patients included in the study. The rates of cancer detection for 10-core and 12-core TRUS-B groups were similar (41.8%, 44.5%, p=0.694, respectively). Besides, there was no significant difference between the mean BMI, median age, prostate volume and PSA values of the groups. Urinary tract infection with fever was found to be higher in 12 patients with TRUS-B but the difference was not statistically significant (3.06% and 4.54%, p=0.578). DISCUSSION and CONCLUSION: The 10-core prostate biopsy appears to be a more applicable biopsy method than the 12-core TRUS-B procedure because of requires less sampling, similar cancer detection and complication rates.
{"title":"Comparison of 10 and 12-Core Prostate Biopsy Efficiencies in Patients with PSA 20 ng-ml","authors":"G. Sönmez, M. Keske, Fatih Demir, N. Hamidi, M. Karadağ","doi":"10.5505/aot.2019.20438","DOIUrl":"https://doi.org/10.5505/aot.2019.20438","url":null,"abstract":"INTRODUCTION: Transrectal ultrasound-guided prostate biopsy (TRUS-B) is the gold standard method used to diagnose prostate cancer. However, how many samples should be taken in TRUS-B procedure is still controversial. The aim of this study is to compare the cancer detection rates of standard 10-core and 12-core TRUS-B procedures. METHODS: Patients who underwent 10-core (Group-1) or 12-core (Group-2) TRUS-B operations were included in this retrospective study for prostate specific antigen (PSA) elevation or suspicious digital examination findings. Patients with PSA>20 ng/ml and a history of negative biopsy were excluded from the study. In addition to cancer detection rates of groups, demographic and clinical data such as age, body mass index (BMI), serum PSA ratios and prostate volume were compared. RESULTS: A total of 208 patients were included in the study (Group-1: 98, Group-2: 110). The rate of cancer detection was 43.2% in all patients included in the study. The rates of cancer detection for 10-core and 12-core TRUS-B groups were similar (41.8%, 44.5%, p=0.694, respectively). Besides, there was no significant difference between the mean BMI, median age, prostate volume and PSA values of the groups. Urinary tract infection with fever was found to be higher in 12 patients with TRUS-B but the difference was not statistically significant (3.06% and 4.54%, p=0.578). DISCUSSION and CONCLUSION: The 10-core prostate biopsy appears to be a more applicable biopsy method than the 12-core TRUS-B procedure because of requires less sampling, similar cancer detection and complication rates.","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123045183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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