S. Ölmez, M. Kaya, D. Kalayci, S. Yılmaz, E. Eskiçırak, S. Ünver
{"title":"Assessment of complications after anesthesia in the postanesthetic care unit of the oncology hospital","authors":"S. Ölmez, M. Kaya, D. Kalayci, S. Yılmaz, E. Eskiçırak, S. Ünver","doi":"10.5505/AOT.2019.49344","DOIUrl":"https://doi.org/10.5505/AOT.2019.49344","url":null,"abstract":"","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128887923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
INTRODUCTION: Retrocaval ureter (RU) is a rare congenital anomaly characterized by the passage of the ureter through the posterior of the vena cava. We aimed to present the data of 8 cases treated with open surgical repair without excision of the retrocaval segment. METHODS: Eight patients who were operated with the diagnosis of RU in our clinic between 2005-2018 were included in the study. Demographic data, periand postoperative data of the patients were recorded and evaluated. In addition, imaging modalities were recorded. Preand postoperative values of T1⁄2 values in dynamic scintigraphy were compared. All patients underwent open ureterouretereral anostomosis without excision of the retrocaval segment. SPSS 22.0 was used for statistical analysis and p values less than 0.05 were considered statistically significant. RESULTS: Five patients were male and 3 were female. The mean age was 36.2 years (25-48). The mean operation time was 64 minutes (58-92). Six patients (75%) presented with flank pain. The mean hospitalization duration was 2.32 days. In the postoperative period, all patients underwent computed tomography-urography and dynamic and static renal scintigraphy with nuclear medicine study. There was no statistically significant difference between preoperative and postoperative static scintigraphy values (p = 0.741), but dynamic renal scintigraphy difference was significant (T1⁄2 was 25.7 min. preoperatively and 14.4 min. postoperatively, p = 0.016). DISCUSSION AND CONCLUSION: Re-anostomosis performed for the retrocaval ureter without any excision of the retrocaval segment yields successful results with minimal postoperative morbidity and short hospital stay.
{"title":"Open Surgical Repair of Retrocaval Ureter Without Excision of Retrocaval Segment: Results of 8 Cases in a Single-Center","authors":"F. Kızılay, S. Kalemci, A. Şimşir, B. Semerci","doi":"10.5505/aot.2019.95866","DOIUrl":"https://doi.org/10.5505/aot.2019.95866","url":null,"abstract":"INTRODUCTION: Retrocaval ureter (RU) is a rare congenital anomaly characterized by the passage of the ureter through the posterior of the vena cava. We aimed to present the data of 8 cases treated with open surgical repair without excision of the retrocaval segment. METHODS: Eight patients who were operated with the diagnosis of RU in our clinic between 2005-2018 were included in the study. Demographic data, periand postoperative data of the patients were recorded and evaluated. In addition, imaging modalities were recorded. Preand postoperative values of T1⁄2 values in dynamic scintigraphy were compared. All patients underwent open ureterouretereral anostomosis without excision of the retrocaval segment. SPSS 22.0 was used for statistical analysis and p values less than 0.05 were considered statistically significant. RESULTS: Five patients were male and 3 were female. The mean age was 36.2 years (25-48). The mean operation time was 64 minutes (58-92). Six patients (75%) presented with flank pain. The mean hospitalization duration was 2.32 days. In the postoperative period, all patients underwent computed tomography-urography and dynamic and static renal scintigraphy with nuclear medicine study. There was no statistically significant difference between preoperative and postoperative static scintigraphy values (p = 0.741), but dynamic renal scintigraphy difference was significant (T1⁄2 was 25.7 min. preoperatively and 14.4 min. postoperatively, p = 0.016). DISCUSSION AND CONCLUSION: Re-anostomosis performed for the retrocaval ureter without any excision of the retrocaval segment yields successful results with minimal postoperative morbidity and short hospital stay.","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130281442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: This cross-sectional study aims to determine the frequency of kinesiophobia in breast cancer survivors and evaluate its relationship with mainly quality of life and comorbidities, also fatigue, lymphedema, and depression. Material Methods: This study included 54 women with breast cancer who were followed in remission in Aydın Atatürk State Hospital Medical Oncology Clinic between November-December 2020. Clinicopathological characteristics of the patients were recorded. Kinesiophobia was assessed using the Turkish version of Tampa Scale for Kinesiophobia (TSK). Lymphedema was evaluated with bilateral upper extremity measurements. Depressive status and quality of life were determined using the Beck Depression Inventory (BDI) and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Version 3.0 (EORTC QLQ-C30 v3). Comorbidities were assessed using the Charlson Comorbidity Index (CCI) while fatigue was evaluated by 10 cm visual analogue scale (VAS). The relationship between the TSK and CCI, BDI, VAS-F, EORTC-30 were investigated. Results: The mean age of patients was 52.11±11.10 years. Of the patients, 36 (66.7%) had kinesiophobia based on having TSK scores above 37. The rate to recieve adjuvant radiotherapy was higher in kinesiophobic group. Kinesiophobic patients had statistically significantly lower global health, physical functioning, and emotional functioning scores, and higher depression and VAS-fatigue scores. Kinesiophobic patients also had higher financial difficulty and higher sypmtom scale scores. Comorbidities and presence of lymphedema did not differ between groups (p>0.05). All EORTC QLQ30 sub-parameter scores except for financial difficulty and symptom severity had negative significant correlations with TSK scores while VAS-fatigue, BDI, EORTC QLQ-30 symptom scale, and financial difficulties showed significant positive correlations. TSK score was not correlated with CCI. Conclusion: Kinesiophobia is rather frequent in breast cancer survivors and has associations with worse quality of life and higher depression and fatigue scores. These patients should be trained and encouraged for an active life style.
{"title":"Kinesiophobia in Breast Cancer Survivors and its Relationship with Quality of Life, Comorbidity, and other clinical parameters","authors":"I. Sunar, V. Sunar","doi":"10.5505/aot.2021.38243","DOIUrl":"https://doi.org/10.5505/aot.2021.38243","url":null,"abstract":"Objectives: This cross-sectional study aims to determine the frequency of kinesiophobia in breast cancer survivors and evaluate its relationship with mainly quality of life and comorbidities, also fatigue, lymphedema, and depression. Material Methods: This study included 54 women with breast cancer who were followed in remission in Aydın Atatürk State Hospital Medical Oncology Clinic between November-December 2020. Clinicopathological characteristics of the patients were recorded. Kinesiophobia was assessed using the Turkish version of Tampa Scale for Kinesiophobia (TSK). Lymphedema was evaluated with bilateral upper extremity measurements. Depressive status and quality of life were determined using the Beck Depression Inventory (BDI) and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Version 3.0 (EORTC QLQ-C30 v3). Comorbidities were assessed using the Charlson Comorbidity Index (CCI) while fatigue was evaluated by 10 cm visual analogue scale (VAS). The relationship between the TSK and CCI, BDI, VAS-F, EORTC-30 were investigated. Results: The mean age of patients was 52.11±11.10 years. Of the patients, 36 (66.7%) had kinesiophobia based on having TSK scores above 37. The rate to recieve adjuvant radiotherapy was higher in kinesiophobic group. Kinesiophobic patients had statistically significantly lower global health, physical functioning, and emotional functioning scores, and higher depression and VAS-fatigue scores. Kinesiophobic patients also had higher financial difficulty and higher sypmtom scale scores. Comorbidities and presence of lymphedema did not differ between groups (p>0.05). All EORTC QLQ30 sub-parameter scores except for financial difficulty and symptom severity had negative significant correlations with TSK scores while VAS-fatigue, BDI, EORTC QLQ-30 symptom scale, and financial difficulties showed significant positive correlations. TSK score was not correlated with CCI. Conclusion: Kinesiophobia is rather frequent in breast cancer survivors and has associations with worse quality of life and higher depression and fatigue scores. These patients should be trained and encouraged for an active life style.","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130977844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Changes in rectum volume can affect dose delivery during prostate radiotherapy. The aim of this study was to evaluate how laxative use affected rectum volumes and doses in patients with prostate cancer treated with Volumetric Modulated Arc Therapy (VMAT). Material and Methods: Treatment planning computed tomography (simCT) and cone-beam computed tomography (CBCT) images collected from 20 patients with prostate cancer were retrospectively evaluated. These patients were divided into two groups as those who either used or did not use laxatives during radiotherapy. Rectum volumes were re-contoured on 160 CBCT images, and VMAT treatment plans were re-calculated to determine rectum doses. Results: In all patients, CBCT images showed increased mean rectum volumes and doses relative to simCT images. Furthermore, the percent volume (Vx) of the rectum receiving 40, 50, 60, and 70 Gy doses based on CBCT results were larger than those based on simCT. The Dmean values in the treatment plans for the group with laxative use were 39 Gy on simCT images and 43 Gy on CBCT images (p = 0.009). Alternatively, in the group without laxatives, the Dmean values in the treatment plans were 40 Gy on simCT images and 44 Gy on CBCT images (p = 0.047). Conclusion: In patients undergoing prostate radiotherapy, rectum volume and doses increase regardless of laxative use. Although laxatives can limit volume expansion of the rectum, they do not have the expected effect on rectum doses and actually significantly increase all dosimetric parameters.
{"title":"The Effects of Laxative Use on Rectum Volume and Doses During Radiotherapy in Patients With Prostate Cancer","authors":"E. Duman, N. Atabek, Y. Bilek","doi":"10.5505/aot.2021.15493","DOIUrl":"https://doi.org/10.5505/aot.2021.15493","url":null,"abstract":"Objective: Changes in rectum volume can affect dose delivery during prostate radiotherapy. The aim of this study was to evaluate how laxative use affected rectum volumes and doses in patients with prostate cancer treated with Volumetric Modulated Arc Therapy (VMAT). Material and Methods: Treatment planning computed tomography (simCT) and cone-beam computed tomography (CBCT) images collected from 20 patients with prostate cancer were retrospectively evaluated. These patients were divided into two groups as those who either used or did not use laxatives during radiotherapy. Rectum volumes were re-contoured on 160 CBCT images, and VMAT treatment plans were re-calculated to determine rectum doses. Results: In all patients, CBCT images showed increased mean rectum volumes and doses relative to simCT images. Furthermore, the percent volume (Vx) of the rectum receiving 40, 50, 60, and 70 Gy doses based on CBCT results were larger than those based on simCT. The Dmean values in the treatment plans for the group with laxative use were 39 Gy on simCT images and 43 Gy on CBCT images (p = 0.009). Alternatively, in the group without laxatives, the Dmean values in the treatment plans were 40 Gy on simCT images and 44 Gy on CBCT images (p = 0.047). Conclusion: In patients undergoing prostate radiotherapy, rectum volume and doses increase regardless of laxative use. Although laxatives can limit volume expansion of the rectum, they do not have the expected effect on rectum doses and actually significantly increase all dosimetric parameters.","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"16 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113965230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Merve Durna, A. Topçu, I. Yurtsever, M. Şimşek, M. Aydın, M. Seker
Adrenocortical carcinoma (ACC) is an uncommon and aggressive tumor. Despite the current treatment options commonly used in ACC, the prognosis is poor. No risk factors have been identified except for genetic predisposition. The most important factors affecting the prognosis are the stage at the time of diagnosis and the resectability of the primary tumor. Here, we present a metastatic ACC case of a 29-year-old woman presented with symptoms of swelling in her feet, abdominal striae, and mild abdominal pain for three months. The abdominal computed tomography scan revealed a 14 cm mass in the right adrenal gland, indistinguishable from the liver and right kidney. Clinicians should consider primary ACC, which has limited treatment options, in the differential diagnosis in the presence of findings such as edema, obesity, and striae.
{"title":"A Giant Metastatic Adrenal Cortical Carcinoma Case Presented with Rapid Progression","authors":"Merve Durna, A. Topçu, I. Yurtsever, M. Şimşek, M. Aydın, M. Seker","doi":"10.5505/aot.2023.57984","DOIUrl":"https://doi.org/10.5505/aot.2023.57984","url":null,"abstract":"Adrenocortical carcinoma (ACC) is an uncommon and aggressive tumor. Despite the current treatment options commonly used in ACC, the prognosis is poor. No risk factors have been identified except for genetic predisposition. The most important factors affecting the prognosis are the stage at the time of diagnosis and the resectability of the primary tumor. Here, we present a metastatic ACC case of a 29-year-old woman presented with symptoms of swelling in her feet, abdominal striae, and mild abdominal pain for three months. The abdominal computed tomography scan revealed a 14 cm mass in the right adrenal gland, indistinguishable from the liver and right kidney. Clinicians should consider primary ACC, which has limited treatment options, in the differential diagnosis in the presence of findings such as edema, obesity, and striae.","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121195740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CALR, JAK2 and MPL Genes Mutations in Myeloproliferative Neoplasms, Single Center Experience","authors":"T. Bahşi, T. Yiğenoğlu","doi":"10.5505/aot.2019.03521","DOIUrl":"https://doi.org/10.5505/aot.2019.03521","url":null,"abstract":"","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129260168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Tekinalp, Hilal Akay Çizmecioğlu, M. H. Göktepe, Sinan Demircioğlu, Ali Kürşat Tuna, M. Karakurt Eryılmaz
{"title":"The Impact of non-COVID-19 Infections to COVID-19 Disease in Hematological and Solid Organ Malignancies","authors":"A. Tekinalp, Hilal Akay Çizmecioğlu, M. H. Göktepe, Sinan Demircioğlu, Ali Kürşat Tuna, M. Karakurt Eryılmaz","doi":"10.5505/aot.2022.03206","DOIUrl":"https://doi.org/10.5505/aot.2022.03206","url":null,"abstract":"","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128588330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nephrogenic adenoma is a rare benign lesion of urothelial mucosa. Our case is an incidentally detected nephrogenic adenoma accompanied by bilateral hydronephrosis. A 59-year-old female. At cystoscopy, suspicious papillary lesion measuring 1 cm was observed on anteior wall of the bladder and transurethral resection was performed.Pathologically, the result was reported as nephrogenic adenoma (nephrogenic metaplasia). The urinary bladder is the most common location of nephrogenic adenom (68.6 %)and it is followed by the urethra (13.5 %),ureter (8.2%), renal pelvis (8.2%) and prostate (2%). Nephrogenic adenomas are strongly associated with chronic irritation or inflammation of the urinary tract. Other malign lesions should be distinguished immunohistochemically and histopathologically. It should be followed for concomitant malignant lesions and frequent local recurrences.
{"title":"Nephrogenic adenoma of the bladder: a case report","authors":"S. Şenel, C. S. Gökkaya, S. Kayaçetin, S. Bulut","doi":"10.5505/AOT.2019.66487","DOIUrl":"https://doi.org/10.5505/AOT.2019.66487","url":null,"abstract":"Nephrogenic adenoma is a rare benign lesion of urothelial mucosa. Our case is an incidentally detected nephrogenic adenoma accompanied by bilateral hydronephrosis. A 59-year-old female. At cystoscopy, suspicious papillary lesion measuring 1 cm was observed on anteior wall of the bladder and transurethral resection was performed.Pathologically, the result was reported as nephrogenic adenoma (nephrogenic metaplasia). The urinary bladder is the most common location of nephrogenic adenom (68.6 %)and it is followed by the urethra (13.5 %),ureter (8.2%), renal pelvis (8.2%) and prostate (2%). Nephrogenic adenomas are strongly associated with chronic irritation or inflammation of the urinary tract. Other malign lesions should be distinguished immunohistochemically and histopathologically. It should be followed for concomitant malignant lesions and frequent local recurrences.","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128554636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: The inflammatory myofibroblastic tumor is rarely located in the breast and, surgical resection is enough for the diagnosis and treatment. Case Report: The patient, a 64-year-old female, was referred to our centre palpable mass in the right breast. Mammography demonstrated a mass of smoothed contour with calcification in the right breast. After three months, segmental mastectomy was planned as the mass grew. Pathological features, micromorphological and immunohistochemical staining have confirmed the lesion as being breast inflammatory myofibroblastic tumor. Conclusion: Inflammatory myofibroblastic tumor of the breast is a rare and intermediate (rarely metastasizing) malignant potential tumor. Due to recurrence and metastasis risk, complete excision with negative margins and regular follow up plays a critical role in treating of inflammatory myofibroblastic tumors.
{"title":"Inflammatory Myofibroblastic Tumor of the Breast in 64 – Year – Old Women","authors":"E. Güner, F. Markoç, C. Özaslan","doi":"10.5505/aot.2022.32848","DOIUrl":"https://doi.org/10.5505/aot.2022.32848","url":null,"abstract":"Introduction: The inflammatory myofibroblastic tumor is rarely located in the breast and, surgical resection is enough for the diagnosis and treatment. Case Report: The patient, a 64-year-old female, was referred to our centre palpable mass in the right breast. Mammography demonstrated a mass of smoothed contour with calcification in the right breast. After three months, segmental mastectomy was planned as the mass grew. Pathological features, micromorphological and immunohistochemical staining have confirmed the lesion as being breast inflammatory myofibroblastic tumor. Conclusion: Inflammatory myofibroblastic tumor of the breast is a rare and intermediate (rarely metastasizing) malignant potential tumor. Due to recurrence and metastasis risk, complete excision with negative margins and regular follow up plays a critical role in treating of inflammatory myofibroblastic tumors.","PeriodicalId":435847,"journal":{"name":"Acta Oncologica Turcica","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129380853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}