The delusional belief one has died is a rare psychopathology. It has been described as a part of Cotard's syndrome and is associated with psychiatric and neurological illnesses. Here we present a case of a 97‐year‐old male patient who experienced this delusion with a background of long‐standing dementia with hearing and vision impairment. There were no associated psychiatric symptoms. Ten days after the onset of the delusion he had a stroke and hemiplegia, and he passed away within a month. We discuss the presentation and analyse the related literature.
{"title":"Delusion of death in a patient with dementia: a case report","authors":"Nilamadhab Kar, Suresh Chandra Rath, Shreyan Kar","doi":"10.1002/pnp.811","DOIUrl":"https://doi.org/10.1002/pnp.811","url":null,"abstract":"The delusional belief one has died is a rare psychopathology. It has been described as a part of Cotard's syndrome and is associated with psychiatric and neurological illnesses. Here we present a case of a 97‐year‐old male patient who experienced this delusion with a background of long‐standing dementia with hearing and vision impairment. There were no associated psychiatric symptoms. Ten days after the onset of the delusion he had a stroke and hemiplegia, and he passed away within a month. We discuss the presentation and analyse the related literature.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136128938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vellingiri Raja Badrakalimuthu, Oliver Bashford, Lovemore Munowenyu
There is significant pressure on the availability of mental health beds for the elderly within the NHS. In concerted efforts to manage this demand, Surrey and Borders Partnership NHS Foundation Trust established an acute care pathway referrals forum (ACP). Here, the authors discuss their initiative, which provided a solution to waiting times where having a daily meeting of senior clinicians and operational managers focused on arriving at a comprehensive management plan, reduced waiting times, freed up beds and facilitated collective learning across various professions, services and agencies.
{"title":"Impact of <scp>ACP</scp> referrals forum on elderly mental health bed pressures","authors":"Vellingiri Raja Badrakalimuthu, Oliver Bashford, Lovemore Munowenyu","doi":"10.1002/pnp.815","DOIUrl":"https://doi.org/10.1002/pnp.815","url":null,"abstract":"There is significant pressure on the availability of mental health beds for the elderly within the NHS. In concerted efforts to manage this demand, Surrey and Borders Partnership NHS Foundation Trust established an acute care pathway referrals forum (ACP). Here, the authors discuss their initiative, which provided a solution to waiting times where having a daily meeting of senior clinicians and operational managers focused on arriving at a comprehensive management plan, reduced waiting times, freed up beds and facilitated collective learning across various professions, services and agencies.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136128939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyperemesis gravidarum occurs in up to 2 % of pregnancies. It is customary to regard the condition as purely an obstetric issue. However, there are reasonable grounds for reframing it as a neuropsychiatric state dependent upon genetic factors and involving peptides active within the central nervous system. Neurological abnormalities can also arise due to Wernicke's encephalopathy and the electrolyte abnormalities of refeeding syndrome. Aside from rehydration and antiemetic drugs, the condition can respond well to certain psychotropic medications and to psychological interventions, it may therefore be reasonable to regard hyperemesis of pregnancy as requiring both psychiatric and medical expertise for comprehensive management.
{"title":"Is hyperemesis gravidarum a neuropsychiatric disorder?","authors":"Simon D Nicholson","doi":"10.1002/pnp.807","DOIUrl":"https://doi.org/10.1002/pnp.807","url":null,"abstract":"Hyperemesis gravidarum occurs in up to 2 % of pregnancies. It is customary to regard the condition as purely an obstetric issue. However, there are reasonable grounds for reframing it as a neuropsychiatric state dependent upon genetic factors and involving peptides active within the central nervous system. Neurological abnormalities can also arise due to Wernicke's encephalopathy and the electrolyte abnormalities of refeeding syndrome. Aside from rehydration and antiemetic drugs, the condition can respond well to certain psychotropic medications and to psychological interventions, it may therefore be reasonable to regard hyperemesis of pregnancy as requiring both psychiatric and medical expertise for comprehensive management.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136129769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cefepime is a fourth‐generation cephalosporin widely used to treat severe infections. However, some patients are at a disproportionately higher risk of developing cefepime‐induced encephalopathy (CIE). While CIE presenting as delirium is not uncommon, it is often missed in clinical practice. Current guidelines recommend prescribing cefepime adjusted for renal clearance to reduce the risk of toxicity. However, this rare case suggests adjusting cefepime for renal dysfunction may be insufficient to prevent CIE. Thus, clinicians must continuously evaluate patients on cefepime therapy to promptly diagnose CIE.
{"title":"Cefepime‐induced delirium","authors":"Malarkodi Suppamutharwyam, Tunku Muzafar Shah","doi":"10.1002/pnp.813","DOIUrl":"https://doi.org/10.1002/pnp.813","url":null,"abstract":"Cefepime is a fourth‐generation cephalosporin widely used to treat severe infections. However, some patients are at a disproportionately higher risk of developing cefepime‐induced encephalopathy (CIE). While CIE presenting as delirium is not uncommon, it is often missed in clinical practice. Current guidelines recommend prescribing cefepime adjusted for renal clearance to reduce the risk of toxicity. However, this rare case suggests adjusting cefepime for renal dysfunction may be insufficient to prevent CIE. Thus, clinicians must continuously evaluate patients on cefepime therapy to promptly diagnose CIE.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136153498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring the ethical issues and clinical use of apps and wearable technology in epilepsy management and risk reduction","authors":"Lauren Cullinan, Reza Kiani","doi":"10.1002/pnp.816","DOIUrl":"https://doi.org/10.1002/pnp.816","url":null,"abstract":"","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136153850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nilema Nasrine, Chloe Stevens, Hoi‐Ying Tam, Vimal Sivasanker
A limited response to clozapine treatment is a familiar clinical scenario in patients with treatment‐resistant schizophrenia. Here, the authors present a case where pharmacogenetic analysis was able to guide clinical management, and the discussion is expanded into the role of clinic genomics in personalised medicine.
{"title":"Using pharmacogenetic analysis in clinical management with clozapine","authors":"Nilema Nasrine, Chloe Stevens, Hoi‐Ying Tam, Vimal Sivasanker","doi":"10.1002/pnp.808","DOIUrl":"https://doi.org/10.1002/pnp.808","url":null,"abstract":"A limited response to clozapine treatment is a familiar clinical scenario in patients with treatment‐resistant schizophrenia. Here, the authors present a case where pharmacogenetic analysis was able to guide clinical management, and the discussion is expanded into the role of clinic genomics in personalised medicine.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136129600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Recurrent painful ophthalmoplegic neuropathy (RPON), formerly known as ophthalmoplegic migraine, is a rare condition characterised by recurrent attacks of unilateral headache with ipsilateral ophthalmoplegia. Although classified as a cranial neuralgia, the exact pathophysiology behind RPON is unclear and the clinical presentation often resembles migraine headaches. Here, the authors present the case of a patient with RPON who, after numerous therapeutic failures, received erenumab and experienced significant improvement. This case supports the argument that RPON should be reclassified as a migraine variant, which would enable the use of specific prophylactic medication in patients suffering from this disorder.
{"title":"Erenumab as treatment for recurrent painful ophthalmoplegic neuropathy","authors":"Darija Mahovic, Matea Bracic","doi":"10.1002/pnp.810","DOIUrl":"https://doi.org/10.1002/pnp.810","url":null,"abstract":"Recurrent painful ophthalmoplegic neuropathy (RPON), formerly known as ophthalmoplegic migraine, is a rare condition characterised by recurrent attacks of unilateral headache with ipsilateral ophthalmoplegia. Although classified as a cranial neuralgia, the exact pathophysiology behind RPON is unclear and the clinical presentation often resembles migraine headaches. Here, the authors present the case of a patient with RPON who, after numerous therapeutic failures, received erenumab and experienced significant improvement. This case supports the argument that RPON should be reclassified as a migraine variant, which would enable the use of specific prophylactic medication in patients suffering from this disorder.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136129781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Subacute cerebellar syndromes have a broad differential diagnosis, which includes paraneoplasia. Paraneoplastic cerebellar degeneration needs to be considered in this clinical situation even if initial brain imaging is normal, and the neurological prognosis is guarded even if the underlying tumour can be successfully treated.
{"title":"Cerebellar syndrome: cause cured, but symptoms persist","authors":"Shehab Samaha, Andrew J Larner","doi":"10.1002/pnp.812","DOIUrl":"https://doi.org/10.1002/pnp.812","url":null,"abstract":"Subacute cerebellar syndromes have a broad differential diagnosis, which includes paraneoplasia. Paraneoplastic cerebellar degeneration needs to be considered in this clinical situation even if initial brain imaging is normal, and the neurological prognosis is guarded even if the underlying tumour can be successfully treated.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136129596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cognitive impairment is a crucial early and late complaint in multiple sclerosis (MS). The exact onset of cognitive impairment in MS and its pathophysiology remain elusive. A simple, easy, and time saving method is crucial for detecting early cognitive complaints, specifically information processing speed, which is important for the functionality of higher cognitive processes. Here, the authors compare the sensitivity and specificity of trail making test part A as a short and free valid test with the symbol digit modality test (SDMT) for assessment of information processing speed in a sample of Egyptian people with MS.
{"title":"Validation of trail making test part A for cognitive screening in multiple sclerosis","authors":"Amira Sayed, Ghada Abdelhadi, Ismail Ramadan, Aya Abdel Galeel, Mervat Hamed","doi":"10.1002/pnp.814","DOIUrl":"https://doi.org/10.1002/pnp.814","url":null,"abstract":"Cognitive impairment is a crucial early and late complaint in multiple sclerosis (MS). The exact onset of cognitive impairment in MS and its pathophysiology remain elusive. A simple, easy, and time saving method is crucial for detecting early cognitive complaints, specifically information processing speed, which is important for the functionality of higher cognitive processes. Here, the authors compare the sensitivity and specificity of trail making test part A as a short and free valid test with the symbol digit modality test (SDMT) for assessment of information processing speed in a sample of Egyptian people with MS.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136129744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samy Salama, Horeya Saadallah, M. Hamed, Heba Abou El Wafa, M. lhab Reda
Although cognitive impairment is one of the common problems among many patients with epilepsy, it is still not well defined in childhood absence epilepsy. Here, the authors assess the cognitive and executive function in childhood absence epilepsy in a group of school‐age children in Egypt. They discuss the need for early identification of neuropsychological dysfunction so that appropriate management can be implemented.
{"title":"Assessing cognitive and executive function in childhood absence epilepsy","authors":"Samy Salama, Horeya Saadallah, M. Hamed, Heba Abou El Wafa, M. lhab Reda","doi":"10.1002/pnp.799","DOIUrl":"https://doi.org/10.1002/pnp.799","url":null,"abstract":"Although cognitive impairment is one of the common problems among many patients with epilepsy, it is still not well defined in childhood absence epilepsy. Here, the authors assess the cognitive and executive function in childhood absence epilepsy in a group of school‐age children in Egypt. They discuss the need for early identification of neuropsychological dysfunction so that appropriate management can be implemented.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48366709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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