K. Gammage, J. Caron, Alyson Crozier, A. Ede, Matt Hoffman, Seungmin Lee, Sascha Leisterer, S. Locke, Desi McEwan, Kathleen T. Mellano, E. Pila, Matthew Stork
Depression and anxiety
抑郁与忧虑
{"title":"Digest","authors":"K. Gammage, J. Caron, Alyson Crozier, A. Ede, Matt Hoffman, Seungmin Lee, Sascha Leisterer, S. Locke, Desi McEwan, Kathleen T. Mellano, E. Pila, Matthew Stork","doi":"10.1002/pnp.189","DOIUrl":"https://doi.org/10.1002/pnp.189","url":null,"abstract":"Depression and anxiety","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pnp.189","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43497224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Gammage, J. Caron, Alyson Crozier, A. Ede, Christopher Hill, Matt Hoffman, Sascha Leisterer, S. Locke, Desi McEwan, Kathleen T. Mellano, E. Pila, Matthew Stork
Safety of ramelteon
框架的安全性
{"title":"Digest","authors":"K. Gammage, J. Caron, Alyson Crozier, A. Ede, Christopher Hill, Matt Hoffman, Sascha Leisterer, S. Locke, Desi McEwan, Kathleen T. Mellano, E. Pila, Matthew Stork","doi":"10.1002/pnp.125","DOIUrl":"https://doi.org/10.1002/pnp.125","url":null,"abstract":"Safety of ramelteon","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pnp.125","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42215016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lithium is the first‐line treatment as a mood stabiliser in bipolar affective disorder, but it is associated with an increased risk of developing chronic kidney disease (CKD). Consideration of ongoing lithium therapy in patients with CKD is a relatively common clinical scenario, but there is a lack of clear clinical guidelines and management practices vary. We discuss two cases of patients on lithium therapy who developed CKD, in order to provide a meaningful context to further explore the clinical framework for decision making and management.
{"title":"Lithium and chronic kidney disease: to stop or not to stop?","authors":"Bharat Velani, R. Tomar","doi":"10.1002/pnp.786","DOIUrl":"https://doi.org/10.1002/pnp.786","url":null,"abstract":"Lithium is the first‐line treatment as a mood stabiliser in bipolar affective disorder, but it is associated with an increased risk of developing chronic kidney disease (CKD). Consideration of ongoing lithium therapy in patients with CKD is a relatively common clinical scenario, but there is a lack of clear clinical guidelines and management practices vary. We discuss two cases of patients on lithium therapy who developed CKD, in order to provide a meaningful context to further explore the clinical framework for decision making and management.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45160752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Digest","authors":"","doi":"10.1002/pnp.794","DOIUrl":"https://doi.org/10.1002/pnp.794","url":null,"abstract":"","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135573808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rare medical conditions present significant challenges to medical professionals in their ability to diagnose, refer appropriately, and offer timely treatment and support. These challenges are made more difficult and daunting in cases of rare conditions with no effective specific treatment, making the need for holistic approach to management and support more important. This article presents a case of a patient with a rare condition – erythromelalgia.
{"title":"Mental health and social sequelae of a rare condition: erythromelalgia","authors":"Gbenga Asigo, S. Parry","doi":"10.1002/pnp.788","DOIUrl":"https://doi.org/10.1002/pnp.788","url":null,"abstract":"Rare medical conditions present significant challenges to medical professionals in their ability to diagnose, refer appropriately, and offer timely treatment and support. These challenges are made more difficult and daunting in cases of rare conditions with no effective specific treatment, making the need for holistic approach to management and support more important. This article presents a case of a patient with a rare condition – erythromelalgia.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45828959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DYT1 dystonia is a rare and genetically inherited childhood‐onset dystonia. Psychiatric comorbidity is increased in patients with dystonia. Here the authors present the case of a 25‐year‐old male with DYTI dystonia, previously treated with deep brain stimulation, who came to the attention of secondary care after a near fatal suicide attempt. The authors also summarise their findings from a literature search on psychiatric disorder in primary dystonia secondary to the DYT1 gene.
{"title":"Psychiatric disorder in DYT1 dystonia","authors":"A. Yahya, Meena Naguib, Shakil Khawaja","doi":"10.1002/pnp.789","DOIUrl":"https://doi.org/10.1002/pnp.789","url":null,"abstract":"DYT1 dystonia is a rare and genetically inherited childhood‐onset dystonia. Psychiatric comorbidity is increased in patients with dystonia. Here the authors present the case of a 25‐year‐old male with DYTI dystonia, previously treated with deep brain stimulation, who came to the attention of secondary care after a near fatal suicide attempt. The authors also summarise their findings from a literature search on psychiatric disorder in primary dystonia secondary to the DYT1 gene.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42575714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Care of patients with functional neurological disorders (FND) is complex, often with poor outcomes. There is currently only low quality evidence of interventions needed for recovery in the acute phase. In this paper the characteristics of a cohort of acute FND patients managed within a large tertiary neurosciences centre are described and health service provision explored to identify fidelity with best practice.
{"title":"Characteristics and multidisciplinary team management of FND","authors":"M. Rixon, K. Clarke, S. Hernandez, W. Bower","doi":"10.1002/pnp.790","DOIUrl":"https://doi.org/10.1002/pnp.790","url":null,"abstract":"Care of patients with functional neurological disorders (FND) is complex, often with poor outcomes. There is currently only low quality evidence of interventions needed for recovery in the acute phase. In this paper the characteristics of a cohort of acute FND patients managed within a large tertiary neurosciences centre are described and health service provision explored to identify fidelity with best practice.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45293735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We present a case of a 27‐year‐old Caucasian male with a background of surgically corrected tetralogy of Fallot (TOF) and pulmonary valve regurgitation, who presented with psychotic symptoms. The case presented a challenge in treatment due to the patient's cardiac history and ongoing cardiac‐related health problems with prolonged QTc before initiation of the antipsychotic drug. Treatment included careful monitoring of ECG while on antipsychotics, which led gradually to improvement in his mental state. The case highlights the possibility of a link between TOF and psychosis, the vulnerability of such patients to their treatment and the importance of multidisciplinary support for cardiac side‐effects.
{"title":"Psychosis treatment in the context of tetralogy of Fallot and prolonged QTc","authors":"Dina D'Souza, N. Kar, S. Jiwanmall","doi":"10.1002/pnp.785","DOIUrl":"https://doi.org/10.1002/pnp.785","url":null,"abstract":"We present a case of a 27‐year‐old Caucasian male with a background of surgically corrected tetralogy of Fallot (TOF) and pulmonary valve regurgitation, who presented with psychotic symptoms. The case presented a challenge in treatment due to the patient's cardiac history and ongoing cardiac‐related health problems with prolonged QTc before initiation of the antipsychotic drug. Treatment included careful monitoring of ECG while on antipsychotics, which led gradually to improvement in his mental state. The case highlights the possibility of a link between TOF and psychosis, the vulnerability of such patients to their treatment and the importance of multidisciplinary support for cardiac side‐effects.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46414891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The comprehensive geriatric assessment has a significant evidence base in both hospital medicine and community‐based medical care although there appears to be limited evidence of the use of this framework in elderly psychiatric patients. The authors discuss its application in multidisciplinary team meetings for older adult psychiatric inpatients, aiming to improve understanding of a broad range of patient needs and improve communication between team members.
{"title":"Comprehensive geriatric assessment for older adult psychiatric inpatients","authors":"K. Hardy, Oliver Mason, Susan Wilkins","doi":"10.1002/pnp.791","DOIUrl":"https://doi.org/10.1002/pnp.791","url":null,"abstract":"The comprehensive geriatric assessment has a significant evidence base in both hospital medicine and community‐based medical care although there appears to be limited evidence of the use of this framework in elderly psychiatric patients. The authors discuss its application in multidisciplinary team meetings for older adult psychiatric inpatients, aiming to improve understanding of a broad range of patient needs and improve communication between team members.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41829425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder, while dementia is a neurodegenerative disorder, both presenting with cognitive deficits and/or behavioural disturbances. Here, the authors review the evidence on similarities and differences between ADHD and dementia in terms of cognitive impairment, risk factors, genetics, neuroanatomy and neurochemical studies in the older adult population. This demonstrates a need for clinicians in memory services to be knowledgeable about ADHD in adults as the two diagnoses can be clinically differentiated by taking a careful history of symptom onset and progression.
{"title":"Exploring the relationship between ADHD and dementia","authors":"Nirja Beehuspoteea, V. Badrakalimuthu","doi":"10.1002/pnp.784","DOIUrl":"https://doi.org/10.1002/pnp.784","url":null,"abstract":"Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder, while dementia is a neurodegenerative disorder, both presenting with cognitive deficits and/or behavioural disturbances. Here, the authors review the evidence on similarities and differences between ADHD and dementia in terms of cognitive impairment, risk factors, genetics, neuroanatomy and neurochemical studies in the older adult population. This demonstrates a need for clinicians in memory services to be knowledgeable about ADHD in adults as the two diagnoses can be clinically differentiated by taking a careful history of symptom onset and progression.","PeriodicalId":43913,"journal":{"name":"Progress in Neurology and Psychiatry","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47704162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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