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“Your Tumour Can Save Lives”: Re-examining Singapore’s Consent Procedures for the Use of De-identified Bio-specimens in Research “你的肿瘤可以挽救生命”:重新审视新加坡在研究中使用去识别生物标本的同意程序
IF 1.1 Q3 ETHICS Pub Date : 2025-04-30 DOI: 10.1007/s41649-024-00327-z
Kylie J. Q. Heng, Shaun S. E. Loong, Gini W. W. Wong, Athena Ham, Aaron D’Sa, Mayank Dalakoti, Roger Foo, Jerry Menikoff

Consent in research is inarguably a highly contentious and debated topic. One of the biggest debates in research ethics revolves around the determination of when consent is necessary, as there is a need to balance participant protections and research advancements. Contrary to popular belief, obtaining informed consent may not necessarily be better for the participant. One illustration of this can be taken from the United States’ (US) 2011 proposal to require consent for the research use of de-identified bio-specimens under the applicable regulations (what is often referred to as the “Common Rule”). The proposed transition from no consent to broad consent was met with strong opposition from researchers and the public alike, highlighting the possible superiority of not requiring consent when de-identified bio-specimens are used in research. Against this backdrop, this article uses legal and bioethical perspectives to evaluate Singapore’s consent procedures for the secondary research use of de-identified bio-specimens, arguing that Singapore is ready and in need of further liberties to allow for more robust research advancements and better participant outcomes.

研究中的同意无疑是一个极具争议和争议的话题。研究伦理中最大的争论之一是确定何时需要同意,因为需要平衡参与者保护和研究进展。与普遍的看法相反,获得知情同意不一定对参与者更好。一个例子可以从美国(US) 2011年的提案中得到说明,该提案要求根据适用法规(通常称为“共同规则”)对去识别生物标本的研究使用表示同意。从未经同意过渡到广泛同意的提议遭到了研究人员和公众的强烈反对,这凸显了在研究中使用去识别的生物标本时不需要征得同意的可能优势。在此背景下,本文从法律和生物伦理的角度来评估新加坡对去识别生物标本的二次研究使用的同意程序,认为新加坡已经准备好并且需要进一步的自由,以允许更强大的研究进展和更好的参与者结果。
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引用次数: 0
The Proliferation of Medical Clinics in Pakistani Street and Health Fragmentation: A Case Study 巴基斯坦街头医疗诊所的激增与卫生碎片化:个案研究
IF 1.1 Q3 ETHICS Pub Date : 2025-04-25 DOI: 10.1007/s41649-024-00328-y
Jamil Ahmed Sheikh, Shuaib Farooq, Shehla Nazmeen, Ghulam Yasin

The proliferation of medical clinics on urban streets in Pakistan presents a paradoxical situation that leads to healthcare fragmentation. Low- and middle-income countries like Pakistan face various challenges, exacerbating inequalities in access to delivery of treatment, low-quality standards, behavioral issues, a lack of accountability, and reduced patient satisfaction, which lead to inefficiencies. This study examines the elements that contribute to this condition, such as patient preferences, organizational incentives, and the amount of patient knowledge. Data was collected through surveys (N = 158) and semi-structured interviews (N = 15) with patients, doctors, and healthcare staff. The research found that the proliferation of clinics and fragmentation of healthcare are not accidental. Various factors contribute to this situation, such as patient preferences and conveniences, referrals by initial physician, organizational panel, proximity, cost, and the level of patient education, among others. The findings highlight the need for concerted efforts to address the issues of trust, coordination, and doctor-patient contact in the healthcare environment.

巴基斯坦城市街道上医疗诊所的激增呈现出一种矛盾的局面,导致医疗保健分散。像巴基斯坦这样的低收入和中等收入国家面临着各种挑战,加剧了获得治疗的不平等、低质量标准、行为问题、缺乏问责制以及患者满意度降低,从而导致效率低下。本研究考察了导致这种情况的因素,如患者偏好、组织激励和患者知识的数量。通过调查(N = 158)和对患者、医生和医护人员的半结构化访谈(N = 15)收集数据。研究发现,诊所的激增和医疗保健的分散并非偶然。造成这种情况的因素多种多样,如患者的偏好和便利、初始医生的转诊、组织小组、距离、成本和患者教育水平等。研究结果强调,需要齐心协力解决医疗环境中的信任、协调和医患接触问题。
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引用次数: 0
Promoting Responsible Use of AI in African Healthcare: Strengthening Patients’ Moral Agency 促进在非洲医疗保健中负责任地使用人工智能:加强患者的道德能动性
IF 1.1 Q3 ETHICS Pub Date : 2025-04-25 DOI: 10.1007/s41649-025-00357-1
Edmund Terem Ugar

Machine learning technologies deployed in several sub-Saharan African countries to assist medical practitioners have shown how such technologies can significantly extend the reach of limited medical personnel and equipment resources. However, while I praise the efficiency of these technologies in carrying out medical diagnosis and treatment recommendations, I raise some critical concerns about the normative shift that may occur in their usage in the region. An uncritical use or overreliance on these technologies may threaten shared decision-making between patients and doctors. While shared decision-making is an integral component of patient-centred care in contemporary medicine that must be respected, from a phenomenological perspective, the stakes are higher for sub-Saharan Africans. For Africans, the threat to shared decision-making may negatively impact a significant aspect of the community–interpersonal relationships. I contend that over-relying on these systems for clinical diagnosis and recommendations may diminish the value of interpersonal relationships between patients and doctors. I show how the practice of interpersonal relationships is integral in making a moral agent (to becoming a member of the moral community) within the sub-Saharan African value systems. Finally, this paper seeks to make novel contributions to value-sensitive healthcare/healthcare technology policies, guidelines and regulations within sub-Saharan Africa and countries in the global South that share similar ethical/cultural worldviews.

一些撒哈拉以南非洲国家为协助医疗从业人员而部署的机器学习技术表明,这些技术如何能够大大扩大有限的医疗人员和设备资源的覆盖范围。然而,虽然我赞扬这些技术在执行医疗诊断和治疗建议方面的效率,但我对这些技术在该区域的使用可能发生的规范转变提出一些严重关切。不加鉴别地使用或过度依赖这些技术可能会威胁到患者和医生之间的共同决策。虽然共同决策是当代医学以病人为中心的护理的一个组成部分,必须得到尊重,但从现象学的角度来看,撒哈拉以南非洲人的利害关系更大。对非洲人来说,共同决策的威胁可能对社区人际关系的一个重要方面产生负面影响。我认为,过度依赖这些系统进行临床诊断和推荐可能会降低医患之间人际关系的价值。我展示了人际关系的实践如何在撒哈拉以南非洲的价值体系中成为一个道德主体(成为道德社区的一员)是不可或缺的。最后,本文旨在为撒哈拉以南非洲和全球南方国家具有相似伦理/文化世界观的价值敏感的医疗保健/医疗保健技术政策、指导方针和法规做出新的贡献。
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引用次数: 0
Drug-Resistant Tuberculosis in Western Province, Papua New Guinea: Is Health Securitisation the Answer, or Merely a PHEIC Promise? 巴布亚新几内亚西部省的耐药结核病:医疗证券化是解决办法,还是仅仅是一个国际关注的公共卫生问题?
IF 1.1 Q3 ETHICS Pub Date : 2025-04-21 DOI: 10.1007/s41649-024-00344-y
George Drewett

Tuberculosis (TB) and multidrug-resistant TB (MDRTB) are a major global health problem, and the Western Province of Papua New Guinea (PNG) has some of the highest rates of TB and MDRTB in the world. Due to its geographical location at the intersection of PNG, Australia and Indonesia, MDRTB in Western Province has significant health security implications. This article explores TB and MDRTB from a global health perspective with reference to the United Nations Millennium Development Goals and Sustainable Development Goals, followed by analysis of the unprecedented outbreak of MDRTB in Western Province PNG. This is followed by a focused history of the regulatory instrument, Public Health Emergency of International Concern (PHEIC), the advantages and disadvantages of declaring a PHEIC for MDRTB, and whether a PHEIC declaration is the right instrument to assist in combating MDRTB in Western Province, and MDRTB globally.

结核病(TB)和耐多药结核病(MDRTB)是一个主要的全球卫生问题,巴布亚新几内亚西部省(PNG)是世界上结核病和耐多药结核病发病率最高的省份之一。由于其位于巴布亚新几内亚、澳大利亚和印度尼西亚交界处的地理位置,西部省的耐多药结核病具有重大的卫生安全影响。本文结合联合国千年发展目标和可持续发展目标,从全球卫生的角度对结核病和耐多药结核病进行了探讨,并对巴布亚新几内亚西部省前所未有的耐多药结核病疫情进行了分析。随后重点介绍了监管工具、国际关注的突发公共卫生事件(PHEIC)的历史、宣布耐多药结核病的PHEIC的利弊,以及宣布PHEIC是否是协助西部省和全球防治耐多药结核病的正确工具。
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引用次数: 0
An Ethical Framework to Clinical Post-Mortem Examination in Saudi Arabia 沙特阿拉伯临床尸检的伦理框架
IF 1.1 Q3 ETHICS Pub Date : 2025-04-21 DOI: 10.1007/s41649-024-00331-3
Ruaim Muaygil, Khaldoon Aljerian

Post-mortem examinations (PME) often yield valuable information regarding the cause and manner of death. They aid in identifying underlying disease, support public health efforts, and inform criminal investigations. In the clinical context, PME improves understanding of disease processes, prevents future illness in others, and provides comfort and closure to families. In Saudi Arabia, a multitude of cultural, religious, and ethical concerns often preclude frank discussions and contribute to the reluctance of both families and practitioners to pursue these examinations. In this paper, we contend that clinical PME should be routinely offered to family members after the unexplained death of an individual. To that end, we propose a religiously informed and culturally sensitive ethical framework, one that is cognizant of local cultural, ethical, and religious needs. We begin with an overview of PME, its development, and its current state in Saudi Arabia. Next, we examine the cultural, religious, and ethical challenges that contribute to the underutilization of PME. Finally, we address these challenges through our proposed framework in the hope that a more representative approach to PME will permit more utilization and benefit.

尸检通常能提供有关死因和死亡方式的宝贵信息。它们有助于识别潜在疾病,支持公共卫生工作,并为刑事调查提供信息。在临床环境中,PME提高了对疾病过程的理解,防止他人未来患病,并为家庭提供安慰和封闭。在沙特阿拉伯,众多的文化、宗教和伦理问题往往阻碍了坦率的讨论,导致家庭和医生都不愿进行这些检查。在本文中,我们认为临床PME应定期提供给家庭成员后,一个人的不明原因的死亡。为此,我们提出了一个宗教知情和文化敏感的伦理框架,一个认识到当地文化、伦理和宗教需求的伦理框架。我们首先概述PME,它的发展,以及它在沙特阿拉伯的现状。接下来,我们将探讨导致PME未充分利用的文化、宗教和伦理挑战。最后,我们通过我们提出的框架来解决这些挑战,希望一个更具代表性的PME方法将允许更多的利用和收益。
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引用次数: 0
Misrepresenting Female Doctors in Pakistan: How the “Doctor Bride” Phenomenon Causes Epistemic Injustice 误传巴基斯坦女医生:“医生新娘”现象如何导致认知不公。
IF 1.1 Q3 ETHICS Pub Date : 2025-04-17 DOI: 10.1007/s41649-024-00329-x
Sundus Iftikhar, Sarosh Saleem

Gender discrimination in the medical profession is a pressing issue in Pakistan, and the derogatory term “Doctor Bride” has perpetuated harmful stereotypes about female doctors. This paper argues that gender biases and societal expectations hinder women from pursuing careers in medicine. The focus on the term and stereotyping of female doctors is based on prejudice, which results in epistemic injustices. It fails to address the systemic issues that keep female doctors out of clinical practice. The cultural norms and prejudices towards women in professional settings exacerbate the challenges they face in pursuing a medical career. These challenges include social and cultural expectations of prioritizing family over careers, biases in healthcare organizations, and discouragement for married women or those with children to pursue certain specialties. This paper highlights the need to address gender discrimination and create a more inclusive environment for women in the medical profession in Pakistan and globally.

在巴基斯坦,医疗行业中的性别歧视是一个紧迫的问题,贬义词“新娘医生”使对女医生的有害成见永久化。本文认为,性别偏见和社会期望阻碍了女性从事医学事业。对女医生的术语和刻板印象的关注是基于偏见的,这导致了认识上的不公正。它未能解决使女医生远离临床实践的系统性问题。在专业环境中对妇女的文化规范和偏见加剧了她们在追求医疗事业时面临的挑战。这些挑战包括社会和文化对家庭优先于职业的期望,医疗机构的偏见,以及对已婚妇女或有孩子的妇女追求某些专业的阻碍。该文件强调需要解决性别歧视问题,并为巴基斯坦和全球医疗行业的妇女创造一个更具包容性的环境。
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引用次数: 0
Myths and Realities about the Private Sector Stem Cell Industry in Malaysia 马来西亚私营部门干细胞产业的神话与现实
IF 1.1 Q3 ETHICS Pub Date : 2025-04-17 DOI: 10.1007/s41649-024-00330-4
Kean Chang Phang, Mohammad Firdaus Bin Abdul Aziz

Notwithstanding its potential medical benefits, there are unproven stem cell–based therapies being offered across the globe. Little is known about the landscape of Malaysia’s private stem cell sector of which this study aims to explore. Qualitative study was conducted to explore its status through empirical interviews with stakeholders in the private sector. This study reveals that private researchers face with limited funding and overwhelming bureaucracies resulting in a low output. There is also a lack of governance for stem cell therapy, and some concerns over how stem cell–based therapies are being offered. Hence, urgent interventions by regulatory authorities are vital to ensure ethical and safe clinical practices in the private sector to protect the reputation of this promising industry.

尽管有潜在的医学益处,但全球各地都在提供未经证实的干细胞疗法。本研究旨在探索的马来西亚私人干细胞部门的情况鲜为人知。通过对私营部门利益相关者的实证访谈,进行了定性研究,以探讨其现状。这项研究揭示了私人科研人员面临资金有限和官僚主义泛滥导致的低产出。干细胞治疗也缺乏管理,一些人担心如何提供基于干细胞的治疗。因此,监管当局的紧急干预对于确保私营部门的道德和安全临床实践至关重要,以保护这一有前途的行业的声誉。
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引用次数: 0
The Value of Implicitness: An Empirical Ethics Analysis of Indonesian Everyday Family Involvement in a Palliative Care Setting 内隐的价值:印尼日常家庭参与缓和疗护的实证伦理分析
IF 1.1 Q3 ETHICS Pub Date : 2025-04-16 DOI: 10.1007/s41649-025-00360-6
Raditya Bagas Wicaksono, Amalia Muhaimin, Dick L. Willems, Jeannette Pols

The lack of professional support for patients needing palliative care in Indonesia leads to a heavier reliance on family members for care. However, family tensions often arise from unmet expectations about support from other family members. This study explores implicitness, which we describe as the use of indirect or unspoken methods to communicate messages. We argue that the value of implicitness strongly influences the communication of these expectations and affects family caregiving dynamics. This paper aims to discuss the hidden expectations shaped by implicitness, what makes it an important value in family care, its ethical implications, and strategies for resolving the problems that arise from it. We conducted ethnographic fieldwork in Banyumas, Indonesia, involving in-depth interviews, home observations, and focus group discussions with patients, families, and health professionals. Data were analyzed through an empirical ethics approach. Our findings indicate that implicitness shapes family expectations regarding involvement of other family members in daily caring activities and financial support. Implicitness serves as an important value as it seeks to preserve sincerity and also maintain harmony, by not directly asking for help. However, implicitness can also lead to underlying family tensions that hinder proper care and reduce the well-being of patients and families. Families were able to resolve problems by accepting difficult circumstances or sharing them with health professionals. We suggest that health professionals should acknowledge the role of implicitness and use active listening skills to identify potential problems. If appropriate, they could help persuade family members to be more actively involved in caregiving through indirect communication. By doing so, they may enhance the well-being of both patients and families without needing every expectation to be directly and explicitly articulated.

在印度尼西亚,需要姑息治疗的患者缺乏专业支持,导致更多地依赖家庭成员提供护理。然而,家庭关系紧张往往是由于对其他家庭成员的支持没有得到满足而引起的。本研究探讨了隐含性,我们将其描述为使用间接或非言语的方法来传达信息。我们认为,内隐的价值强烈影响这些期望的沟通,并影响家庭照顾的动态。本文旨在探讨隐性所形成的隐性期望,它在家庭护理中的重要价值,它的伦理意义,以及解决由此产生的问题的策略。我们在印度尼西亚Banyumas进行了人种学田野调查,包括深度访谈、家庭观察以及与患者、家属和卫生专业人员的焦点小组讨论。通过实证伦理学方法分析数据。我们的研究结果表明,内隐性塑造了家庭对其他家庭成员参与日常照顾活动和经济支持的期望。含蓄是一个重要的价值,因为它寻求保持真诚,也保持和谐,通过不直接寻求帮助。然而,含蓄也可能导致潜在的家庭紧张关系,阻碍适当的护理,降低患者和家庭的福祉。家庭能够通过接受困难情况或与保健专业人员分享来解决问题。我们建议卫生专业人员应该承认隐性的作用,并使用积极的倾听技巧来识别潜在的问题。如果合适,他们可以通过间接沟通帮助说服家庭成员更积极地参与照顾。通过这样做,他们可以提高病人和家庭的福祉,而不需要每个期望都直接和明确地表达出来。
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引用次数: 0
Thoughts and Behaviors of Chinese and Japanese Doctors when faced with the Death of a Patient: A Qualitative Descriptive Study of Doctors’ Responses to a Hypothetical Scenario 中日医生面对病人死亡时的思想与行为:一种假设情景下医生反应的定性描述研究
IF 1.1 Q3 ETHICS Pub Date : 2025-04-02 DOI: 10.1007/s41649-024-00326-0
Hua Xu, Taketoshi Okita, Masao Tabata, Yasuhiro Kadooka, Atsushi Asai

China and Japan have similar cultures but differing healthcare systems. In both countries, admissions of medical error and apologies by doctors continue to be an important but difficult issue. The present study aimed to examine and compare the thoughts and behaviors of Chinese and Japanese doctors when faced with the unexpected death of a patient. Qualitative descriptive analysis was performed to compare the responses of 20 doctors from each country to a hypothetical scenario involving the death of a patient. We found that almost all doctors in both countries considered the treatment process described in the hypothetical scenario to be inappropriate and most would feel regret when faced with the young patient’s death. There was a disagreement concerning responsibility for the patient death among the doctors regardless of their nationality. Doctors decided how to behave facing the patient death after anticipating the bereaved family’s reaction and their initial responses varied widely. Japanese doctors indicated that they would communicate with the patient’s family after a patient died, whereas none of the Chinese doctors indicated they would do so due to a fear of physical violence from the bereaved family. Finally, the decision on whether to disclose the medical error and apology was made after careful and complex consideration. In conclusion, significant differences were observed between Chinese and Japanese doctors with respect to communicating with, and disclosing errors and apologizing to, the bereaved family. We discuss both the ethical and social implications of these differences.

中国和日本有着相似的文化,但医疗体系不同。在这两个国家,承认医疗失误和医生道歉仍然是一个重要但困难的问题。本研究旨在检验和比较中国和日本医生在面对病人意外死亡时的想法和行为。进行定性描述性分析,比较来自每个国家的20名医生对涉及患者死亡的假设情景的反应。我们发现,两国几乎所有的医生都认为假设情景中描述的治疗过程是不合适的,大多数人在面对年轻患者的死亡时会感到遗憾。不论国籍的医生对病人死亡的责任存在分歧。医生在预测病人家属的反应后决定如何面对病人的死亡,他们最初的反应差别很大。日本医生表示,他们会在病人去世后与病人家属沟通,而中国医生则没有人表示他们会这样做,因为他们担心失去亲人的家庭会对他们进行身体暴力。最后,是否公开医疗失误和道歉的决定是经过仔细而复杂的考虑后做出的。综上所述,中日两国医生在与家属沟通、错误披露、道歉等方面存在显著差异。我们将讨论这些差异的伦理和社会含义。
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引用次数: 0
Emerging Priorities in Asian Paediatric Ethics 亚洲儿科伦理的新优先事项
IF 1.3 Q3 ETHICS Pub Date : 2025-04-02 DOI: 10.1007/s41649-025-00367-z
Roy Joseph, Dominic Wilkinson
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引用次数: 0
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Asian Bioethics Review
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