首页 > 最新文献

"Medical & pharmaceutical journal "Pulse"最新文献

英文 中文
PROVIDING REHABILITATION ACTIVITIES TO PATIENTS WHO UNDERWENT CARDIOVASCULAR EVENTS IN THE ASTRAKHAN REGION 为阿斯特拉罕地区发生心血管事件的患者提供康复活动
Pub Date : 2021-08-30 DOI: 10.26787/nydha-2686-6838-2021-23-8-88-94
Ermolaev D.O., Ermolaeva Yu.N., Zolotokopova Zh.Yu.
The relevance of the study is explained by the need to increase attention to the situation with acute cardiovascular diseases and the creation of an accessible system of medical rehabilitation for patients with cardiovascular diseases in the region. The aim of the study is to analyze the provision of rehabilitation measures for patients who have suffered cardiovascular accidents in the Astrakhan region. Materials and methods - based on the data of the annual reporting statistical forms No. 12 "Information on the number of diseases registered in patients living in the service area of the medical institution" and No. 14 "Information on the activities of the hospital", the calculation and analysis of indicators of general and primary morbidity was carried out ( on appeal), hospitalized morbidity, hospital mortality, the need for rehabilitation measures and their provision of adult patients aged 18 years and older with diseases of the circulatory system, including cardiovascular accidents in the Astrakhan region. Results and discussion - the article shows the general situation with the incidence of diseases of the circulatory system of the adult population, including acute coronary syndrome and acute cerebrovascular accident in dynamics from 2014 to 2020, discloses the organizational and structural aspects of the existing system of organizing rehabilitation care in the region. The results of assessing the satisfaction of the needs of the adult population of the region in neuro- and cardiac rehabilitation by medical organizations licensed for medical activities with an indication of the work (services) for medical rehabilitation and participating in the federal and territorial program of state guarantees of free provision of medical care to citizens in the region are presented. It was revealed that less than half of those in need receive medical rehabilitation assistance at the expense of the mandatory medical insurance fund. Proposals have been formulated to increase the availability of rehabilitation care for patients who have undergone cardiovascular accidents. Conclusion. The obtained research data can be used for further organizational, methodological and coordination work to provide modern medical and rehabilitation care to patients with acute cardiovascular accidents at the regional level.
这项研究的意义在于,需要进一步关注急性心血管疾病的情况,并为该地区的心血管疾病患者建立一个可获得的医疗康复系统。本研究的目的是分析在阿斯特拉罕地区为遭受心血管事故的患者提供的康复措施。材料和方法————根据年度报告统计表第12号"关于在医疗机构服务区域居住的病人所登记的疾病数量的资料"和第14号"关于医院活动的资料"的数据,计算和分析了一般和初级发病率(经上诉)、住院发病率、住院死亡率、在阿斯特拉罕地区,需要采取康复措施,并为18岁及以上的循环系统疾病,包括心血管事故的成年患者提供康复措施。结果和讨论——文章展示了2014年至2020年成人循环系统疾病发病率的总体情况,包括急性冠状动脉综合征和急性脑血管事故的动态变化,揭示了该地区现有组织康复护理系统的组织和结构方面。介绍了在医疗活动中获得许可并注明医疗康复工作(服务)的医疗机构对该地区成年人口的神经和心脏康复需求的满足情况进行评估的结果,并介绍了参与联邦和地区国家保障向该地区公民免费提供医疗服务方案的结果。据透露,只有不到一半的有需要的人得到由强制性医疗保险基金支付的医疗康复援助。已提出建议,以增加心血管事故患者康复护理的可得性。结论。获得的研究数据可用于进一步的组织、方法和协调工作,以便在区域一级为急性心血管事故患者提供现代医疗和康复护理。
{"title":"PROVIDING REHABILITATION ACTIVITIES TO PATIENTS WHO UNDERWENT CARDIOVASCULAR EVENTS IN THE ASTRAKHAN REGION","authors":"Ermolaev D.O., Ermolaeva Yu.N., Zolotokopova Zh.Yu.","doi":"10.26787/nydha-2686-6838-2021-23-8-88-94","DOIUrl":"https://doi.org/10.26787/nydha-2686-6838-2021-23-8-88-94","url":null,"abstract":"The relevance of the study is explained by the need to increase attention to the situation with acute cardiovascular diseases and the creation of an accessible system of medical rehabilitation for patients with cardiovascular diseases in the region. The aim of the study is to analyze the provision of rehabilitation measures for patients who have suffered cardiovascular accidents in the Astrakhan region. Materials and methods - based on the data of the annual reporting statistical forms No. 12 \"Information on the number of diseases registered in patients living in the service area of the medical institution\" and No. 14 \"Information on the activities of the hospital\", the calculation and analysis of indicators of general and primary morbidity was carried out ( on appeal), hospitalized morbidity, hospital mortality, the need for rehabilitation measures and their provision of adult patients aged 18 years and older with diseases of the circulatory system, including cardiovascular accidents in the Astrakhan region. Results and discussion - the article shows the general situation with the incidence of diseases of the circulatory system of the adult population, including acute coronary syndrome and acute cerebrovascular accident in dynamics from 2014 to 2020, discloses the organizational and structural aspects of the existing system of organizing rehabilitation care in the region. The results of assessing the satisfaction of the needs of the adult population of the region in neuro- and cardiac rehabilitation by medical organizations licensed for medical activities with an indication of the work (services) for medical rehabilitation and participating in the federal and territorial program of state guarantees of free provision of medical care to citizens in the region are presented. It was revealed that less than half of those in need receive medical rehabilitation assistance at the expense of the mandatory medical insurance fund. Proposals have been formulated to increase the availability of rehabilitation care for patients who have undergone cardiovascular accidents. Conclusion. The obtained research data can be used for further organizational, methodological and coordination work to provide modern medical and rehabilitation care to patients with acute cardiovascular accidents at the regional level.","PeriodicalId":445713,"journal":{"name":"\"Medical & pharmaceutical journal \"Pulse\"","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115874065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FEATURES OF PASSING AND FETAL CONDITION WITH MULTIPLE PREGNANCY, WHICH IS COMPLICATED BY FETO-FETAL TRANSFUSION SYNDROME 多胎妊娠并发胎-胎输血综合征的特点及胎儿状况
Pub Date : 2021-08-30 DOI: 10.26787/nydha-2686-6838-2021-23-8-70-76
Bragina T.V., Petrov Yu.A., Palieva N.V.
Problem of multiple pregnancy is one of the most relevant in obstetrics nowadays,being not only a medical, but also a socially significant problem. The problem of pregnancy management is of scientific and practical interest, it is caused by an increase in the number of multiple pregnancies. The current trend towards all cases of multiple pregnancies is explained by the activity of assisted reproductive technologies, the ever-increasing age of women in labor. This article discusses the features of the gestation period in multiple pregnancies, characteristic complications, as well as the features of the condition of the fetus and newborn in this condition. Multiple pregnancy is a model of fetoplacental insufficiency, which is explained by the fact that evolutionarily a woman's body is adapted to bear one fetus. According to research data, the course of multiple pregnancies is more often associated with the presence of various complications than the course of a singleton pregnancy. One of the most serious complications of multiple pregnancy is fetal-fetal transfusion syndrome. The occurrence of this complication requires the use of special tactics of pregnancy management, continuous monitoring of the condition of the mother and fetus, readiness to make emergency correct decisions about prolonging pregnancy or delivery, readiness to provide highly specialized assistance to the fetus and subsequent newborns. Clinical management of pregnancy, treatment and prognosis depend on the extent of development of feto-fetal transfusion syndrome, gestation, on which has developed the syndrome, presence or absence of the mother's genital or extragenital pathology, as well as the fetus. The main methods of treatment of feto-fetal transfusion syndrome are methods of fetal surgery, the most effective of which is the method of fetoscopic coagulation of placental anastomoses.
多胎妊娠是当今产科最重要的问题之一,不仅是一个医学问题,而且是一个重大的社会问题。妊娠管理问题是一个具有科学和现实意义的问题,它是由多胎妊娠数量的增加引起的。目前所有多胎妊娠的趋势都是由辅助生殖技术的活动、分娩妇女年龄的不断增加所解释的。本文讨论了多胎妊娠的妊娠期特点、特征性并发症,以及多胎妊娠胎儿和新生儿的状况特点。多胎妊娠是一种胎胎盘功能不全的模式,这可以用一个事实来解释,即从进化的角度来看,女性的身体适应了一个胎儿。根据研究数据,多胎妊娠比单胎妊娠更容易出现各种并发症。多胎妊娠最严重的并发症之一是胎-胎输血综合征。这种并发症的发生需要使用特殊的妊娠管理策略,持续监测母亲和胎儿的状况,准备好对延长妊娠或分娩做出紧急正确的决定,准备好向胎儿和随后的新生儿提供高度专业化的帮助。妊娠的临床管理、治疗和预后取决于胎-胎儿输血综合征的发展程度、发生该综合征的妊娠情况、母亲的生殖器或生殖器外病变是否存在以及胎儿的情况。治疗胎胎输血综合征的主要方法是胎儿手术方法,其中最有效的方法是胎儿镜下胎盘吻合口凝血法。
{"title":"FEATURES OF PASSING AND FETAL CONDITION WITH MULTIPLE PREGNANCY, WHICH IS COMPLICATED BY FETO-FETAL TRANSFUSION SYNDROME","authors":"Bragina T.V., Petrov Yu.A., Palieva N.V.","doi":"10.26787/nydha-2686-6838-2021-23-8-70-76","DOIUrl":"https://doi.org/10.26787/nydha-2686-6838-2021-23-8-70-76","url":null,"abstract":"Problem of multiple pregnancy is one of the most relevant in obstetrics nowadays,being not only a medical, but also a socially significant problem. The problem of pregnancy management is of scientific and practical interest, it is caused by an increase in the number of multiple pregnancies. The current trend towards all cases of multiple pregnancies is explained by the activity of assisted reproductive technologies, the ever-increasing age of women in labor. This article discusses the features of the gestation period in multiple pregnancies, characteristic complications, as well as the features of the condition of the fetus and newborn in this condition. Multiple pregnancy is a model of fetoplacental insufficiency, which is explained by the fact that evolutionarily a woman's body is adapted to bear one fetus. According to research data, the course of multiple pregnancies is more often associated with the presence of various complications than the course of a singleton pregnancy. One of the most serious complications of multiple pregnancy is fetal-fetal transfusion syndrome. The occurrence of this complication requires the use of special tactics of pregnancy management, continuous monitoring of the condition of the mother and fetus, readiness to make emergency correct decisions about prolonging pregnancy or delivery, readiness to provide highly specialized assistance to the fetus and subsequent newborns. Clinical management of pregnancy, treatment and prognosis depend on the extent of development of feto-fetal transfusion syndrome, gestation, on which has developed the syndrome, presence or absence of the mother's genital or extragenital pathology, as well as the fetus. The main methods of treatment of feto-fetal transfusion syndrome are methods of fetal surgery, the most effective of which is the method of fetoscopic coagulation of placental anastomoses.","PeriodicalId":445713,"journal":{"name":"\"Medical & pharmaceutical journal \"Pulse\"","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128305636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DISADVANTAGES IN THE ORGANIZATION OF OUTPATIENT AND POLYCLINIC SERVICES IN THE FIELD OF MAXILLOFACIAL SURGERY FOR ADULTS AND CHILDREN IN THE GBUZ PENZA REGIONAL CLINICAL HOSPITAL NAMED AFTER V.I. N.N. BURDENKO FOR THE PERIOD 2018 -2020 在2018 -2020年期间,以v.v.n . n . burdenko命名的gbuz penza地区临床医院在成人和儿童颌面外科领域的门诊和综合诊所服务组织方面的劣势
Pub Date : 2021-07-30 DOI: 10.26787/nydha-2686-6838-2021-23-7-6-12
Lebedev M.V., Zakharova I.Yu.
The availability and quality of medical care is determined by the state of primary health care. Optimization and development of outpatient care is the primary task of healthcare. For the Penza region, according to the resolution of the Government of the Penza region of 02.10.2013 N 743-PP, improving the quality of outpatient care in the field of maxillofacial surgery and increasing its availability is one of the primary tasks for our region. In this regard, the assessment of the work of the outpatient office of the Department of Maxillofacial Surgery of the Consultative Polyclinic of the State Budgetary Healthcare Institution of the Penza Regional Clinical Hospital named after V.I. N.N. Burdenko.Aim: to analyze the work and effectiveness of a dentist - surgeon in the outpatient office of the consultative polyclinic GBUZ Penza Regional Clinical Hospital named after V.I. N.N. Burdenko.Materials and methods. To achieve this goal, a retrospective analysis of the primary accounting and reporting medical documentation for 2018–2020 was carried out, a questionnaire survey of patients hospitalized through an outpatient office in the Department of Maxillofacial Surgery of the N.I. N.N. Burdenko. Statistical data analysis procedures were carried out using MS Office Excel 2010 spreadsheets and PASW Statistics 18 statistical software package.Results. The analyzed accounting and reporting medical documentation for 2018–2020, the results of the questionnaire indicate the ineffective work of the doctor surgeon - dentist in the outpatient office of the consultative polyclinic GBUZ POKB im. NN Burdenko, the workload of the department with non-core hospitalizations, the increased workload on doctors - the department of maxillofacial surgery. The ways of solving the problem of replacing a dentist-surgeon with a doctor-maxillofacial surgeon are proposed; on the organization of a rehabilitation room for patients of the adult and pediatric population with pathology of the maxillofacial region; to create a single case history.Conclusion. Carrying out the above changes will reduce the burden on doctors - maxillofacial surgeons of the Department of Maxillofacial Surgery, transfer some of the manipulations from the inpatient to the outpatient service (inpatient replacement technology), thereby improving the medical care service in the field of maxillofacial surgery in the Penza region.
医疗服务的提供和质量取决于初级卫生保健的状况。优化和发展门诊服务是卫生保健工作的首要任务。对于奔萨地区,根据奔萨地区政府2013年10月2日N 743-PP决议,提高颌面外科领域门诊服务的质量并增加其可用性是我们地区的主要任务之一。在这方面,对以v.i.n.n. Burdenko命名的奔萨地区临床医院国家预算保健机构咨询综合诊所颌面外科门诊部的工作进行了评估。目的:分析以v.i.n.n. Burdenko命名的GBUZ奔萨地区临床医院会诊综合诊所门诊部的一名牙医-外科医生的工作和效果。材料和方法。为了实现这一目标,对2018-2020年的主要会计和报告医疗文件进行了回顾性分析,并对通过N.I. N.N. Burdenko颌面外科门诊住院的患者进行了问卷调查。统计数据分析程序采用MS Office Excel 2010电子表格和PASW Statistics 18统计软件包进行。对2018-2020年的会计和报告医疗文件进行分析,问卷调查结果表明,GBUZ POKB im咨询综合诊所门诊部的医生-外科牙医工作效率低下。NN Burdenko,非核心住院部门的工作量,增加了医生的工作量-颌面外科。提出了解决牙颌外科医师替代牙颌外科医师问题的途径;关于成人和儿童颌面部病变患者康复室的组织;创建一个单一的病例历史。实施上述改革将减轻颌面外科医生的负担,将部分手法从住院转移到门诊(住院替代技术),从而提高奔萨地区颌面外科领域的医疗服务水平。
{"title":"DISADVANTAGES IN THE ORGANIZATION OF OUTPATIENT AND POLYCLINIC SERVICES IN THE FIELD OF MAXILLOFACIAL SURGERY FOR ADULTS AND CHILDREN IN THE GBUZ PENZA REGIONAL CLINICAL HOSPITAL NAMED AFTER V.I. N.N. BURDENKO FOR THE PERIOD 2018 -2020","authors":"Lebedev M.V., Zakharova I.Yu.","doi":"10.26787/nydha-2686-6838-2021-23-7-6-12","DOIUrl":"https://doi.org/10.26787/nydha-2686-6838-2021-23-7-6-12","url":null,"abstract":"The availability and quality of medical care is determined by the state of primary health care. Optimization and development of outpatient care is the primary task of healthcare. For the Penza region, according to the resolution of the Government of the Penza region of 02.10.2013 N 743-PP, improving the quality of outpatient care in the field of maxillofacial surgery and increasing its availability is one of the primary tasks for our region. In this regard, the assessment of the work of the outpatient office of the Department of Maxillofacial Surgery of the Consultative Polyclinic of the State Budgetary Healthcare Institution of the Penza Regional Clinical Hospital named after V.I. N.N. Burdenko.\u0000Aim: to analyze the work and effectiveness of a dentist - surgeon in the outpatient office of the consultative polyclinic GBUZ Penza Regional Clinical Hospital named after V.I. N.N. Burdenko.\u0000Materials and methods. To achieve this goal, a retrospective analysis of the primary accounting and reporting medical documentation for 2018–2020 was carried out, a questionnaire survey of patients hospitalized through an outpatient office in the Department of Maxillofacial Surgery of the N.I. N.N. Burdenko. Statistical data analysis procedures were carried out using MS Office Excel 2010 spreadsheets and PASW Statistics 18 statistical software package.\u0000Results. The analyzed accounting and reporting medical documentation for 2018–2020, the results of the questionnaire indicate the ineffective work of the doctor surgeon - dentist in the outpatient office of the consultative polyclinic GBUZ POKB im. NN Burdenko, the workload of the department with non-core hospitalizations, the increased workload on doctors - the department of maxillofacial surgery. The ways of solving the problem of replacing a dentist-surgeon with a doctor-maxillofacial surgeon are proposed; on the organization of a rehabilitation room for patients of the adult and pediatric population with pathology of the maxillofacial region; to create a single case history.\u0000Conclusion. Carrying out the above changes will reduce the burden on doctors - maxillofacial surgeons of the Department of Maxillofacial Surgery, transfer some of the manipulations from the inpatient to the outpatient service (inpatient replacement technology), thereby improving the medical care service in the field of maxillofacial surgery in the Penza region.","PeriodicalId":445713,"journal":{"name":"\"Medical & pharmaceutical journal \"Pulse\"","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116685294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IMPROVEMENT OF THE PROCESS APPROACH IN THE ROUTING OF PATIENTS WITH MALIGNANT MALIGNANCES OF THE MAXILLOFACIAL REGION IN THE TERRITORY OF THE PENZA REGION IN 2021 2021年奔萨地区颌面部恶性肿瘤患者手术路径的改进
Pub Date : 2021-07-30 DOI: 10.26787/nydha-2686-6838-2021-23-7-149-155
Lebedev M.V., Kerimova K.I., Zakharova I.Yu.
The worldwide concern about oncological morbidity is due to the steady increase in the detection rate of malignant neoplasms, which has a tendency to increase. More than 7 million people die from oncology every year in the world. The system of organizing the provision of medical care to the population with oncological diseases in the Russian Federation is currently undergoing a stage of improvement. New programs are aimed at early diagnosis and prevention of malignant neoplasms. Each region has the right to create and implement routing taking into account the territorial characteristics and the existing material and technical base and personnel. The routing system, created for a specific region, determines the order of treatment of patients and the functions of all links in the system of providing medical care to patients with oncopathology. An optimized system for routing patients according to the "Oncology" profile for patients with malignant neoplasms of the maxillofacial region should be structured in accordance with the regional healthcare system. A complex system of interaction, an information system capable of containing and processing a set of information, a trained interested staff dictate the need for making management decisions in the direction of optimizing the oncological service. Management decisions and technologies should be focused on improving the quality and speed of patient admission, providing highly qualified medical care using modern equipment and algorithms. The staff, in turn, determines the basis of the health care system, in connection with which it is necessary to continue education, identify and search for specialists that a specific organization needs, on which the functioning of the entire service for providing medical care to patients with oncopathology of the maxillofacial region depends. In general, the optimization of the system of providing medical care to patients with malignant neoplasms of the maxillofacial region dictates the need to combine organizational measures and a clinical approach. Unambiguously, the multi-component system of integration of various directions and departments in the process of organizing an oncological service predetermines the need to use modern management technologies and the use of all available resources in order to improve the quality of medical care.
世界范围内对肿瘤发病率的关注是由于恶性肿瘤的检出率稳步上升,并有上升的趋势。全世界每年有700多万人死于肿瘤。在俄罗斯联邦,组织向患有肿瘤疾病的人口提供医疗服务的制度目前正处于改进阶段。新的项目旨在早期诊断和预防恶性肿瘤。每个地区都有权根据其领土特点和现有的物质技术基础和人员制定和实施路线。为特定区域创建的路由系统确定了患者的治疗顺序以及为肿瘤病理患者提供医疗服务系统中所有环节的功能。针对颌面部恶性肿瘤患者,根据“肿瘤学”特征,应根据区域卫生保健系统构建优化的患者路径系统。一个复杂的交互系统,一个能够包含和处理一组信息的信息系统,一个训练有素的感兴趣的工作人员,决定了在优化肿瘤服务的方向上做出管理决策的需要。管理决策和技术应侧重于提高患者入院的质量和速度,使用现代设备和算法提供高质量的医疗服务。反过来,工作人员决定了医疗保健系统的基础,在此基础上,有必要继续教育,确定和寻找特定组织需要的专家,为颌面部肿瘤病理患者提供医疗保健的整个服务的功能取决于此。总的来说,为颌面部恶性肿瘤患者提供医疗服务的系统优化要求将组织措施与临床方法相结合。毫无疑问,在组织肿瘤服务的过程中,各个方向和部门的多组件集成系统预先决定了需要使用现代管理技术和利用所有可用资源,以提高医疗质量。
{"title":"IMPROVEMENT OF THE PROCESS APPROACH IN THE ROUTING OF PATIENTS WITH MALIGNANT MALIGNANCES OF THE MAXILLOFACIAL REGION IN THE TERRITORY OF THE PENZA REGION IN 2021","authors":"Lebedev M.V., Kerimova K.I., Zakharova I.Yu.","doi":"10.26787/nydha-2686-6838-2021-23-7-149-155","DOIUrl":"https://doi.org/10.26787/nydha-2686-6838-2021-23-7-149-155","url":null,"abstract":"The worldwide concern about oncological morbidity is due to the steady increase in the detection rate of malignant neoplasms, which has a tendency to increase. More than 7 million people die from oncology every year in the world. The system of organizing the provision of medical care to the population with oncological diseases in the Russian Federation is currently undergoing a stage of improvement. New programs are aimed at early diagnosis and prevention of malignant neoplasms. Each region has the right to create and implement routing taking into account the territorial characteristics and the existing material and technical base and personnel. The routing system, created for a specific region, determines the order of treatment of patients and the functions of all links in the system of providing medical care to patients with oncopathology. An optimized system for routing patients according to the \"Oncology\" profile for patients with malignant neoplasms of the maxillofacial region should be structured in accordance with the regional healthcare system. A complex system of interaction, an information system capable of containing and processing a set of information, a trained interested staff dictate the need for making management decisions in the direction of optimizing the oncological service. Management decisions and technologies should be focused on improving the quality and speed of patient admission, providing highly qualified medical care using modern equipment and algorithms. The staff, in turn, determines the basis of the health care system, in connection with which it is necessary to continue education, identify and search for specialists that a specific organization needs, on which the functioning of the entire service for providing medical care to patients with oncopathology of the maxillofacial region depends. In general, the optimization of the system of providing medical care to patients with malignant neoplasms of the maxillofacial region dictates the need to combine organizational measures and a clinical approach. Unambiguously, the multi-component system of integration of various directions and departments in the process of organizing an oncological service predetermines the need to use modern management technologies and the use of all available resources in order to improve the quality of medical care.","PeriodicalId":445713,"journal":{"name":"\"Medical & pharmaceutical journal \"Pulse\"","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122675973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THERAPEUTIC METHODS FOR TREATMENT OF DENTAL DISCOLORITIS 牙变色炎的治疗方法
Pub Date : 2021-07-30 DOI: 10.26787/nydha-2686-6838-2021-23-7-114-120
M. T.V., Titova O.Yu., Burov A.I., L. N-M, Linnik L.N., Dajronas S.K., Dajronas E.G.
The problem of discoloration of teeth, especially accompanied by increased sensitivity, does not lose its relevance in modern dentistry. Despite the presence in the arsenal of dentists of a significant number of means and methods for solving this problem, it does not go away, but, on the contrary, is overgrown with new complaints. In this work, we analyzed the frequency to analyze the frequency of choice of therapeutic methods for treating discoloration of teeth by patients of dental clinics. A questionnaire was developed for a dentist on the patient's choice of a therapeutic method for eliminating dental discoloration and a survey of 30 dentists (10 - therapists, 10 - orthopedists and 10 - general dentists) was conducted for 2019 and 6 months of 2020. It was found that during this period, 184 out of 331 patients who applied to dental clinics with this problem used therapeutic methods for eliminating tooth discoloration: tooth enamel coating with varnish ("Colordent" + adhesive "Single Bond") was carried out in 16.6% of patients, clinical bleaching of enamel in 32.6% of patients with tooth discoloration, intracoronal bleaching followed by direct restoration (replacement of existing fillings with new ones) in 53.8%. The analysis showed that therapeutic methods for eliminating discoloration of teeth predominate slightly, 55%. Of course, in choosing this direction, the doctor is guided by the clinical situation, IROPZ, taking into account the wishes of the patient and his capabilities. However, it seems necessary to develop and test new, gentle and resistant to mechanical stress methods for eliminating discoloration of economy-class teeth with the possibility of solving the problem of increased tooth sensitivity.
牙齿变色的问题,特别是伴随着敏感性的增加,在现代牙科中并没有失去它的相关性。尽管牙医的武库中有大量的手段和方法来解决这个问题,但它并没有消失,相反,新的抱怨却越来越多。在这项工作中,我们通过分析频率来分析牙科诊所患者对治疗牙齿变色的治疗方法的选择频率。在2019年和2020年的6个月里,对30名牙医(10名治疗师、10名骨科医生和10名普通牙医)进行了调查,并为一名牙医编写了一份关于患者选择消除牙齿变色治疗方法的调查问卷。在此期间,就诊于牙科诊所的331例患者中,有184例患者采用了消除牙齿变色的治疗方法:16.6%的患者进行了牙釉质涂漆(“Colordent”+粘合剂“Single Bond”),32.6%的患者进行了牙釉质临床漂白,53.8%的患者进行了牙釉质冠内漂白后直接修复(用新填充物替换现有填充物)。分析表明,消除牙齿变色的治疗方法占比略高,为55%。当然,在选择这个方向时,医生是根据临床情况,IROPZ,考虑到病人的意愿和他的能力来指导的。然而,有必要开发和试验新的、温和的、抗机械应力的方法来消除经济舱牙齿的变色,并有可能解决牙齿敏感性增加的问题。
{"title":"THERAPEUTIC METHODS FOR TREATMENT OF DENTAL DISCOLORITIS","authors":"M. T.V., Titova O.Yu., Burov A.I., L. N-M, Linnik L.N., Dajronas S.K., Dajronas E.G.","doi":"10.26787/nydha-2686-6838-2021-23-7-114-120","DOIUrl":"https://doi.org/10.26787/nydha-2686-6838-2021-23-7-114-120","url":null,"abstract":"The problem of discoloration of teeth, especially accompanied by increased sensitivity, does not lose its relevance in modern dentistry. Despite the presence in the arsenal of dentists of a significant number of means and methods for solving this problem, it does not go away, but, on the contrary, is overgrown with new complaints. In this work, we analyzed the frequency to analyze the frequency of choice of therapeutic methods for treating discoloration of teeth by patients of dental clinics. A questionnaire was developed for a dentist on the patient's choice of a therapeutic method for eliminating dental discoloration and a survey of 30 dentists (10 - therapists, 10 - orthopedists and 10 - general dentists) was conducted for 2019 and 6 months of 2020. It was found that during this period, 184 out of 331 patients who applied to dental clinics with this problem used therapeutic methods for eliminating tooth discoloration: tooth enamel coating with varnish (\"Colordent\" + adhesive \"Single Bond\") was carried out in 16.6% of patients, clinical bleaching of enamel in 32.6% of patients with tooth discoloration, intracoronal bleaching followed by direct restoration (replacement of existing fillings with new ones) in 53.8%. The analysis showed that therapeutic methods for eliminating discoloration of teeth predominate slightly, 55%. Of course, in choosing this direction, the doctor is guided by the clinical situation, IROPZ, taking into account the wishes of the patient and his capabilities. However, it seems necessary to develop and test new, gentle and resistant to mechanical stress methods for eliminating discoloration of economy-class teeth with the possibility of solving the problem of increased tooth sensitivity.","PeriodicalId":445713,"journal":{"name":"\"Medical & pharmaceutical journal \"Pulse\"","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122003309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
THE DIET OF PERSONS ENGAGED IN SPORTS AT THE AGE OF 40 YEARS AND OLDER 40岁及以上从事体育运动人士的饮食
Pub Date : 2021-07-30 DOI: 10.26787/nydha-2686-6838-2021-23-7-74-79
Cherkasov S.N., Grigoriev G.Yu., Fedyaeva A.V.
The purpose of the study: to analyze the nutritional characteristics of people aged 40 years and older who are engaged in sports (athletics, participation in competitions at distances of 10 km or more). Materials and methods. Nutrition characteristics were studied based on information obtained from a survey of amateur athletes aged 40 years and older competing in track and field events at distances of 10 kilometers or more. In total, 1800 questionnaires were distributed, 1649 completed questionnaires were collected. The following food characteristics were taken into account: the presence or absence of adherence to any diet, the frequency of meals, the regularity of meals, the nature of the food, the significance of the quality of the food consumed, as well as the presence of the fact of eating flour, sweet. The analysis was carried out in three age groups: 40–49 years, 50–59 years and 60 years and older. Results. According to this study, the desire to eat exclusively healthy food with lots of fresh vegetables and fruits, the commitment to diet, the desire to control the quality of food in the group of veteran athletes does not increase, but decreases. People who are engaged in sports, aged 40 years and older, try to eat often and at the same time. In men, with increasing age, the number of people who want to take the largest amount of food for breakfast decreases, while in women, the opposite trend is observed. The commitment to snacks is more characteristic of women than men. The majority of respondents involved in sports, aged 40 years and older, do not deny themselves frequent use of sweet and flour products and with age this desire increases.
研究目的:分析40岁及以上从事体育运动(田径、参加10公里及以上距离的比赛)的人群的营养特征。材料和方法。营养特征的研究是基于对40岁及以上参加10公里及以上田径比赛的业余运动员的调查所得的信息。共发放问卷1800份,回收问卷1649份。以下食物特征被考虑在内:是否坚持任何饮食,吃饭的频率,吃饭的规律,食物的性质,所吃食物质量的重要性,以及是否吃面粉和甜食。分析在三个年龄组进行:40-49岁,50-59岁和60岁及以上。结果。根据这项研究,在资深运动员群体中,只吃含有大量新鲜蔬菜和水果的健康食品的愿望,对饮食的承诺,控制食物质量的愿望并没有增加,而是减少了。从事体育运动的人,年龄在40岁以上,尽量在同一时间经常吃东西。在男性中,随着年龄的增长,想要在早餐时吃最多食物的人数减少,而在女性中,观察到的趋势正好相反。女性比男性更喜欢吃零食。大多数参与体育运动的受访者,年龄在40岁及以上,并不否认自己经常使用甜食和面粉产品,而且随着年龄的增长,这种欲望也在增加。
{"title":"THE DIET OF PERSONS ENGAGED IN SPORTS AT THE AGE OF 40 YEARS AND OLDER","authors":"Cherkasov S.N., Grigoriev G.Yu., Fedyaeva A.V.","doi":"10.26787/nydha-2686-6838-2021-23-7-74-79","DOIUrl":"https://doi.org/10.26787/nydha-2686-6838-2021-23-7-74-79","url":null,"abstract":"The purpose of the study: to analyze the nutritional characteristics of people aged 40 years and older who are engaged in sports (athletics, participation in competitions at distances of 10 km or more). Materials and methods. Nutrition characteristics were studied based on information obtained from a survey of amateur athletes aged 40 years and older competing in track and field events at distances of 10 kilometers or more. In total, 1800 questionnaires were distributed, 1649 completed questionnaires were collected. The following food characteristics were taken into account: the presence or absence of adherence to any diet, the frequency of meals, the regularity of meals, the nature of the food, the significance of the quality of the food consumed, as well as the presence of the fact of eating flour, sweet. The analysis was carried out in three age groups: 40–49 years, 50–59 years and 60 years and older. Results. According to this study, the desire to eat exclusively healthy food with lots of fresh vegetables and fruits, the commitment to diet, the desire to control the quality of food in the group of veteran athletes does not increase, but decreases. People who are engaged in sports, aged 40 years and older, try to eat often and at the same time. In men, with increasing age, the number of people who want to take the largest amount of food for breakfast decreases, while in women, the opposite trend is observed. The commitment to snacks is more characteristic of women than men. The majority of respondents involved in sports, aged 40 years and older, do not deny themselves frequent use of sweet and flour products and with age this desire increases.","PeriodicalId":445713,"journal":{"name":"\"Medical & pharmaceutical journal \"Pulse\"","volume":"47 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114021204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FUNCTIONAL MAPPING OF THE MEDICINES’ QUALITY CONTROL SYSTEM PROCESSES IN THE SVERDLOVSK REGION 斯维尔德洛夫斯克地区药品质量控制系统过程的功能映射
Pub Date : 2021-07-30 DOI: 10.26787/nydha-2686-6838-2021-23-7-156-161
Kantorovich A.Y., Petrov A.L., Andrianova G.N.
The article describes the results of subject-object and risk-based mapping of the medicines’ quality control system. Identification and procedural structuring of key processes of drug quality control systems in Russia was carried out. The matrix of key procedures was formed in coordinates of agency, target, time, and level characteristics for qualitative mapping of the processes and procedures. To quantify the control measures modality in the coordinates "product-context", the structural coefficient of distribution of procedures was calculated for each section of the commodity distribution network: the product emphasis in the production/ manufacturing segment and the environmental emphasis in the system of market distribution of medicines. Based on the results of risk-based mapping, it was determined that the segments of wholesale and retail pharmaceutical activities are characterized by a shift in control measures to the segment of external reactive procedures, which seems to be a negative trend. It is shown that the production of medicines is the leading segment in the implementation of risk-based quality control procedures for medicines, while in the wholesale and retail trade segment this indicator is 95% lower. The key target for optimization measures is the regional wholesale and retail segment of the pharmaceutical market due to the risk-based selective approach to checking compliance with licensing requirements and a large number of control objects.
本文描述了药品质量控制系统的主客体和基于风险的映射结果。对俄罗斯药品质量控制体系关键流程进行了识别和程序构建。在机构、目标、时间和水平特征的坐标中形成关键程序矩阵,以便对过程和程序进行定性映射。为了量化坐标“产品-环境”中的控制措施模式,计算了商品分销网络每个部分的程序分配结构系数:生产/制造部分的产品重点和药品市场分销系统的环境重点。根据基于风险的制图结果,确定了批发和零售药品活动的部分特征是控制措施转向外部反应程序部分,这似乎是一个消极的趋势。研究表明,药品生产是实施基于风险的药品质量控制程序的主要部门,而在批发和零售贸易部门,这一指标要低95%。优化措施的关键目标是药品市场的区域批发和零售部分,因为基于风险的选择性方法来检查许可要求的合规性,并且控制对象大量。
{"title":"FUNCTIONAL MAPPING OF THE MEDICINES’ QUALITY CONTROL SYSTEM PROCESSES IN THE SVERDLOVSK REGION","authors":"Kantorovich A.Y., Petrov A.L., Andrianova G.N.","doi":"10.26787/nydha-2686-6838-2021-23-7-156-161","DOIUrl":"https://doi.org/10.26787/nydha-2686-6838-2021-23-7-156-161","url":null,"abstract":"The article describes the results of subject-object and risk-based mapping of the medicines’ quality control system. Identification and procedural structuring of key processes of drug quality control systems in Russia was carried out. The matrix of key procedures was formed in coordinates of agency, target, time, and level characteristics for qualitative mapping of the processes and procedures. To quantify the control measures modality in the coordinates \"product-context\", the structural coefficient of distribution of procedures was calculated for each section of the commodity distribution network: the product emphasis in the production/ manufacturing segment and the environmental emphasis in the system of market distribution of medicines. Based on the results of risk-based mapping, it was determined that the segments of wholesale and retail pharmaceutical activities are characterized by a shift in control measures to the segment of external reactive procedures, which seems to be a negative trend. It is shown that the production of medicines is the leading segment in the implementation of risk-based quality control procedures for medicines, while in the wholesale and retail trade segment this indicator is 95% lower. The key target for optimization measures is the regional wholesale and retail segment of the pharmaceutical market due to the risk-based selective approach to checking compliance with licensing requirements and a large number of control objects.","PeriodicalId":445713,"journal":{"name":"\"Medical & pharmaceutical journal \"Pulse\"","volume":"199 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116169120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
CASE OF AORTOCORONARY BYPASS SURGERY IN A PATIENT WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION, MULTIVESSEL CORONARY LESIONS AND LOW EJECTION FRACTION st段抬高型心肌梗死、多支冠状动脉病变及低射血分数患者行冠状动脉搭桥手术1例
Pub Date : 2021-07-30 DOI: 10.26787/nydha-2686-6838-2021-23-7-95-100
Jalilov A.K.
For decades, coronary artery bypass grafting (CABG) has been the main method of myocardial revascularization in patients with coronary artery disease, including those with acute coronary syndrome (ACS). Over the past decades, with the development of endovascular interventions and the development of drug-eluting stents, percutaneous coronary intervention (PCI) has become the main method of revascularization after ACS. [1,6]. Acute coronary syndrome (ACS) includes clinical manifestations such as unstable angina pectoris (NS), acute non-ST-segment elevation myocardial infarction (STEMI), and ST-segment elevation myocardial infarction (STEMI). Approximately 40% of all patients diagnosed with ACS have multivessel coronary artery disease, for which coronary artery bypass grafting (CABG) is better than PCI. [2]. The majority of studies comparing PCI and CABG have mainly included patients with stable coronary artery disease who underwent planned myocardial revascularization, rather than those requiring emergency or urgent myocardial revascularization. Thus, the results of these studies have limited applicability to patients with ACS. However, the long-term results of these studies, in particular the low need for re-revascularization, a lower rate of re-myocardial infarction, and the survival benefits of CABG, still need to be considered when determining the best course of treatment for ACS. The current recommendations for treatment in most patients with ACS give preference to early revascularization using PCI or CABG [3, 4]. Thus, our main goal here is to provide the current indications and options for surgical revascularization of the coronary arteries, including current guidelines and the latest published literature. In STEMI patients, early PCI of the main lesion remains the gold standard because it provides the fastest revascularization of the ischemic myocardium and is generally better tolerated than emergency CABG [5]. Since up to 50% of STEMI patients have multivessel coronary artery disease, early arterial revascularization without myocardial infarction has been recommended to provide optimal opportunities for myocardial rescue, reduction of ischemic watershed and improvement of left ventricular function [6,7]. A clinical case of successful beating coronary artery bypass grafting in a patient with ST-segment elevation myocardial infarction, multivessel coronary artery disease and low ejection fraction. The patient was discharged on the 11th day after surgery without complications.
几十年来,冠状动脉旁路移植术(CABG)一直是冠状动脉疾病(包括急性冠状动脉综合征(ACS))患者心肌血运重建的主要方法。近几十年来,随着血管内介入技术的发展和药物洗脱支架的发展,经皮冠状动脉介入治疗(PCI)已成为ACS后血管重建术的主要方法。(1,6)。急性冠脉综合征(Acute coronary syndrome, ACS)包括不稳定型心绞痛(NS)、急性非st段抬高型心肌梗死(STEMI)、st段抬高型心肌梗死(STEMI)等临床表现。大约40%被诊断为ACS的患者有多支冠状动脉疾病,冠状动脉旁路移植术(CABG)比PCI更好。[2]. 大多数比较PCI和CABG的研究主要是针对稳定的冠状动脉疾病患者进行有计划的心肌血运重建,而不是那些需要急诊或紧急心肌血运重建的患者。因此,这些研究结果对ACS患者的适用性有限。然而,在确定ACS的最佳治疗方案时,这些研究的长期结果,特别是低再血运重建需求,较低的再心肌梗死率,以及CABG的生存益处,仍然需要考虑。目前对大多数ACS患者的治疗建议优先采用PCI或CABG进行早期血运重建[3,4]。因此,我们的主要目标是提供当前冠状动脉手术血运重建术的适应症和选择,包括当前的指南和最新发表的文献。在STEMI患者中,早期主要病变PCI仍然是金标准,因为它能提供最快的缺血心肌血运重建,并且通常比急诊CABG耐受性更好[5]。由于高达50%的STEMI患者患有多支冠状动脉疾病,建议在无心肌梗死的情况下进行早期动脉血运重建术,为心肌抢救、减少缺血分水岭和改善左心室功能提供最佳机会[6,7]。st段抬高型心肌梗死伴多支冠状动脉病变低射血分数患者搏动冠状动脉搭桥术成功一例。术后第11天出院,无并发症。
{"title":"CASE OF AORTOCORONARY BYPASS SURGERY IN A PATIENT WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION, MULTIVESSEL CORONARY LESIONS AND LOW EJECTION FRACTION","authors":"Jalilov A.K.","doi":"10.26787/nydha-2686-6838-2021-23-7-95-100","DOIUrl":"https://doi.org/10.26787/nydha-2686-6838-2021-23-7-95-100","url":null,"abstract":"For decades, coronary artery bypass grafting (CABG) has been the main method of myocardial revascularization in patients with coronary artery disease, including those with acute coronary syndrome (ACS). Over the past decades, with the development of endovascular interventions and the development of drug-eluting stents, percutaneous coronary intervention (PCI) has become the main method of revascularization after ACS. [1,6]. Acute coronary syndrome (ACS) includes clinical manifestations such as unstable angina pectoris (NS), acute non-ST-segment elevation myocardial infarction (STEMI), and ST-segment elevation myocardial infarction (STEMI). Approximately 40% of all patients diagnosed with ACS have multivessel coronary artery disease, for which coronary artery bypass grafting (CABG) is better than PCI. [2]. The majority of studies comparing PCI and CABG have mainly included patients with stable coronary artery disease who underwent planned myocardial revascularization, rather than those requiring emergency or urgent myocardial revascularization. Thus, the results of these studies have limited applicability to patients with ACS. However, the long-term results of these studies, in particular the low need for re-revascularization, a lower rate of re-myocardial infarction, and the survival benefits of CABG, still need to be considered when determining the best course of treatment for ACS. The current recommendations for treatment in most patients with ACS give preference to early revascularization using PCI or CABG [3, 4]. Thus, our main goal here is to provide the current indications and options for surgical revascularization of the coronary arteries, including current guidelines and the latest published literature. In STEMI patients, early PCI of the main lesion remains the gold standard because it provides the fastest revascularization of the ischemic myocardium and is generally better tolerated than emergency CABG [5]. Since up to 50% of STEMI patients have multivessel coronary artery disease, early arterial revascularization without myocardial infarction has been recommended to provide optimal opportunities for myocardial rescue, reduction of ischemic watershed and improvement of left ventricular function [6,7]. A clinical case of successful beating coronary artery bypass grafting in a patient with ST-segment elevation myocardial infarction, multivessel coronary artery disease and low ejection fraction. The patient was discharged on the 11th day after surgery without complications.","PeriodicalId":445713,"journal":{"name":"\"Medical & pharmaceutical journal \"Pulse\"","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121827005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
POSITIVE EFFECT ON THE MANIFESTATION OF SEXUAL DYSFUNCTION IN WOMEN OF COC CONTAINING ESTRADIOL VALERATE IN COMBINATION WITH DIENOGEST WITH A DYNAMIC DOSAGE REGIMEN 动态给药方案下含戊酸雌二醇coc联合dienogest对女性性功能障碍表现的积极影响
Pub Date : 2021-07-30 DOI: 10.26787/nydha-2686-6838-2021-23-7-62-67
K. O.B.
Combined oral contraceptives (COC), as drugs containing hormones, can negatively affect sexual function in women of reproductive age. Various causes of sexual dysfunction when taking COC have been studied: a decrease in the concentration of testosterone in the blood due to an increase in globulin, which binds sex steroids, under the influence of oral contraceptives. This mechanism is realized due to the action of two components of COC, both estrogenic and progestogenic. Female sex hormones are known to play an important role in the physiology of sexual desire and behavior. The importance of the most important of them, estrogens, in the sexual behavior of women is to prevent atrophic processes in the vagina, enhance vaginal and vulvar blood circulation, as well as to maintain sensory peripheral perception and the beneficial effect of these processes on the central nervous system. The presented clinical case demonstrates the positive effect of Claira (a drug that is a COC containing estradiol valerate in combination with dienogest with a dynamic dosage regimen) on sexual function. The content of this oral contraceptive of estrogen, identical to natural, eliminates the negative impact of COC on sexual function. Estradiol and estriol, formed during the metabolism of estradiol valerate, actively bind to receptors and have their effects in the tissues of the urogenital tract, having a positive effect on the manifestations of sexual dysfunction. Switching to the drug Clair from other COCs can normalize the condition of women who have decreased sexual function when taking a contraceptive of a different composition and mechanism of action, which was confirmed by this clinical study.
复方口服避孕药(COC)作为一种含有激素的药物,会对育龄妇女的性功能产生负面影响。研究了服用COC时出现性功能障碍的各种原因:口服避孕药影响下,结合性类固醇的球蛋白增加,导致血液中睾酮浓度下降。这一机制是由于COC的雌激素和孕激素两种成分的作用而实现的。众所周知,女性性激素在性欲和性行为的生理上起着重要作用。其中最重要的,雌激素,在女性的性行为中的重要性是防止阴道萎缩过程,增强阴道和外阴的血液循环,以及维持感觉外周感知和这些过程对中枢神经系统的有益作用。本临床病例证明了Claira(一种含有戊酸雌二醇的COC药物,与dienogest联合使用,采用动态给药方案)对性功能的积极作用。这种口服避孕药的雌激素含量与天然避孕药相同,消除了COC对性功能的负面影响。雌二醇和雌三醇在戊酸雌二醇代谢过程中形成,主动与受体结合,在泌尿生殖道组织中发挥作用,对性功能障碍的表现有积极作用。在服用不同成分和作用机制的避孕药时,从其他COCs切换到Clair药物可以使性功能下降的女性的状况正常化,这一点在本临床研究中得到了证实。
{"title":"POSITIVE EFFECT ON THE MANIFESTATION OF SEXUAL DYSFUNCTION IN WOMEN OF COC CONTAINING ESTRADIOL VALERATE IN COMBINATION WITH DIENOGEST WITH A DYNAMIC DOSAGE REGIMEN","authors":"K. O.B.","doi":"10.26787/nydha-2686-6838-2021-23-7-62-67","DOIUrl":"https://doi.org/10.26787/nydha-2686-6838-2021-23-7-62-67","url":null,"abstract":"Combined oral contraceptives (COC), as drugs containing hormones, can negatively affect sexual function in women of reproductive age. Various causes of sexual dysfunction when taking COC have been studied: a decrease in the concentration of testosterone in the blood due to an increase in globulin, which binds sex steroids, under the influence of oral contraceptives. This mechanism is realized due to the action of two components of COC, both estrogenic and progestogenic. Female sex hormones are known to play an important role in the physiology of sexual desire and behavior. The importance of the most important of them, estrogens, in the sexual behavior of women is to prevent atrophic processes in the vagina, enhance vaginal and vulvar blood circulation, as well as to maintain sensory peripheral perception and the beneficial effect of these processes on the central nervous system. The presented clinical case demonstrates the positive effect of Claira (a drug that is a COC containing estradiol valerate in combination with dienogest with a dynamic dosage regimen) on sexual function. The content of this oral contraceptive of estrogen, identical to natural, eliminates the negative impact of COC on sexual function. Estradiol and estriol, formed during the metabolism of estradiol valerate, actively bind to receptors and have their effects in the tissues of the urogenital tract, having a positive effect on the manifestations of sexual dysfunction. Switching to the drug Clair from other COCs can normalize the condition of women who have decreased sexual function when taking a contraceptive of a different composition and mechanism of action, which was confirmed by this clinical study.","PeriodicalId":445713,"journal":{"name":"\"Medical & pharmaceutical journal \"Pulse\"","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133023364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NEUROMUSCULAR MANIFESTATIONS AND COMPLICATIONS OF COVID-19 INFECTION COVID-19感染的神经肌肉表现和并发症
Pub Date : 2021-07-30 DOI: 10.26787/nydha-2686-6838-2021-23-7-108-113
Akhmadeeva L.R., Izhbuldina E.V., Khairullin A.T.
In this paper, various neuromuscular manifestations of coronavirus infection are considered and methods of damage to the nervous system are highlighted. These include the "cytokine storm", impaired hemostasis, neurotropicity and neurovirulence of SARS-CoV-2. The persistence of the virus in the body affects the course of comorbid diseases, which requires a systematic approach to patient treatment. In this paper we discuss the data from modern research papers and clinical cases both from updated international literature and from our own clinical practice: it is the most frequently met condition - Guillain-Barré syndrome – acute inflammatory demyelinating polyneuropathy. We present both rare and common neuro-muscular conditions, their clinical onset, possible pathogenesis, variants of manifestation. According to the data from current publications, the evaluation and management of patients suffering from Guillain-Barré syndrome associated with new coronaviral infection SARS-CoV-2 is does not have major differences with the classical ones, that are not associated with the pandemic. Our patient that we present as our own case, was hospitalized, and observed as an in-patient. She was treated using plasma exchange in the algorithm of management. The outcome of this case was positive. We conclude that neuromuscular manifestation of new coronaviral infection SARS-CoV-2 could be new and possibly associated with this disease, but also could be described as worsening of the premorbid disorders. For instance, inherited neuromuscular diseases could have different variants during the period of pandemic caused by novel coronavirus SARS-CoV-2 infection.
本文考虑了冠状病毒感染的各种神经肌肉表现,并重点介绍了神经系统损伤的方法。这些包括SARS-CoV-2的“细胞因子风暴”、止血功能受损、神经嗜性和神经毒力。病毒在体内的持续存在会影响合并症的病程,因此需要对患者采取系统的治疗方法。本文讨论了现代研究论文和临床病例的数据,包括最新的国际文献和我们自己的临床实践:它是最常见的情况-格林-巴-巴综合征-急性炎症性脱髓鞘性多神经病变。我们提出罕见和常见的神经肌肉疾病,他们的临床发病,可能的发病机制,变体的表现。根据现有文献资料,对新型冠状病毒感染SARS-CoV-2相关格林-巴罗综合征患者的评估和管理与与大流行无关的经典病例没有重大差异。我们的病人是我们自己的病例,他住院了,作为住院病人来观察。在管理算法中采用血浆置换治疗。这个案例的结果是积极的。我们的结论是,新型冠状病毒感染SARS-CoV-2的神经肌肉表现可能是新的,可能与该疾病有关,但也可能被描述为病前疾病的恶化。例如,在新型冠状病毒SARS-CoV-2感染引起的大流行期间,遗传性神经肌肉疾病可能会有不同的变异。
{"title":"NEUROMUSCULAR MANIFESTATIONS AND COMPLICATIONS OF COVID-19 INFECTION","authors":"Akhmadeeva L.R., Izhbuldina E.V., Khairullin A.T.","doi":"10.26787/nydha-2686-6838-2021-23-7-108-113","DOIUrl":"https://doi.org/10.26787/nydha-2686-6838-2021-23-7-108-113","url":null,"abstract":"In this paper, various neuromuscular manifestations of coronavirus infection are considered and methods of damage to the nervous system are highlighted. These include the \"cytokine storm\", impaired hemostasis, neurotropicity and neurovirulence of SARS-CoV-2. The persistence of the virus in the body affects the course of comorbid diseases, which requires a systematic approach to patient treatment. In this paper we discuss the data from modern research papers and clinical cases both from updated international literature and from our own clinical practice: it is the most frequently met condition - Guillain-Barré syndrome – acute inflammatory demyelinating polyneuropathy. We present both rare and common neuro-muscular conditions, their clinical onset, possible pathogenesis, variants of manifestation. According to the data from current publications, the evaluation and management of patients suffering from Guillain-Barré syndrome associated with new coronaviral infection SARS-CoV-2 is does not have major differences with the classical ones, that are not associated with the pandemic. Our patient that we present as our own case, was hospitalized, and observed as an in-patient. She was treated using plasma exchange in the algorithm of management. The outcome of this case was positive. We conclude that neuromuscular manifestation of new coronaviral infection SARS-CoV-2 could be new and possibly associated with this disease, but also could be described as worsening of the premorbid disorders. For instance, inherited neuromuscular diseases could have different variants during the period of pandemic caused by novel coronavirus SARS-CoV-2 infection.","PeriodicalId":445713,"journal":{"name":"\"Medical & pharmaceutical journal \"Pulse\"","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116723505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
"Medical & pharmaceutical journal "Pulse"
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1