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Short-Term Hip Fracture Outcomes during the COVID-19 Pandemic. COVID-19大流行期间髋部骨折的短期结局。
IF 0.9 Pub Date : 2022-01-17 eCollection Date: 2022-01-01 DOI: 10.1055/s-0041-1741511
Samuel Walters, Hassan Raja, Rachel Ahmad, Konstantinos Tsitskaris

Introduction  Despite many significant changes as a result of the coronavirus disease 2019 (COVID-19) pandemic, and reductions in overall trauma workload, patients with fragility hip fractures continued to present to hospital. As we plan for ongoing service provision during future waves of the pandemic, valuable lessons can be learned from patients that have been treated surgically during the "first wave." Methods  All patients admitted to our center (a busy District General Hospital in London, United Kingdom) with a hip fracture during a 13-week period representing the initial rise ("United Kingdom first wave") in COVID-19 cases, from February 17 th to May 17 th , 2020 (study group) were compared with hip fracture patients from the equivalent 13-week period in February to May 2019 (control group). The primary outcome was 30-day mortality, and additional information was collected in terms of length of stay (LOS), SARS-CoV-2 antigen testing, and cause of death. Results  During the COVID-19 study period, 69 patients were admitted with a hip fracture, compared with 70 patients in the control group ( p  = 0.949). There was no significant difference in 30-day mortality between the two groups (5.8 vs. 7.1%, p  = 0.747). Mean LOS was shorter in the COVID-19 period compared with the control group (11.6 vs. 19.6 days, p <0.001, effect size 0.572). Forty-six patients (66.7%) had a SARS-CoV-2 antigen swab test, as testing was not available in the early period, and 10 patients (14.5%) tested positive. None of the patients, who presented before the antigen testing was available, had clinical suspicion of COVID-19 retrospectively. Two "COVID-19 positive" patients (20%) died within 30 days of admission. Conclusion  We report reassuring short-term results demonstrating no statistically significant difference in the 30-day mortality rate of hip fracture patients admitted during the United Kingdom's first wave of the COVID-19 pandemic compared to the equivalent period in the previous year. Hip fracture incidence remained stable, and LOS was reduced, likely due to recent departmental changes as well as a drive to discharge patients quickly during the pandemic. We agree with existing reports that elderly hip fracture patients with COVID-19 have a higher risk of perioperative mortality, however, our results suggest that overall mortality for the whole hip fracture population was similar to the previous year, in which deaths were more commonly attributed to respiratory infections associated with other pathogens. Further work may be needed to evaluate the outcomes during subsequent waves of the pandemic as mutations in the virus and conditions may affect outcomes.

尽管2019冠状病毒病(COVID-19)大流行带来了许多重大变化,并且总体创伤工作量有所减少,但脆性髋部骨折患者仍继续住院。当我们计划在未来的大流行浪潮中继续提供服务时,可以从在“第一波”期间接受手术治疗的患者身上吸取宝贵的经验教训。方法将2020年2月17日至5月17日(研究组)我们中心(英国伦敦一家繁忙的地区综合医院)收治的所有在2019年2月17日至5月17日的13周期间(“英国第一波”)发生的2019年COVID-19病例首次上升(“英国第一波”)的髋部骨折患者与2019年2月至5月的13周期间(对照组)的髋部骨折患者进行比较。主要终点是30天死亡率,并收集了住院时间(LOS)、SARS-CoV-2抗原检测和死亡原因方面的额外信息。结果在新冠肺炎研究期间,69例患者髋部骨折入院,对照组为70例(p = 0.949)。两组30天死亡率无显著差异(5.8% vs. 7.1%, p = 0.747)。与对照组相比,COVID-19期间的平均LOS较短(11.6天对19.6天)。结论我们报告了令人放心的短期结果,表明在英国第一波COVID-19大流行期间入院的髋部骨折患者的30天死亡率与前一年同期相比没有统计学上的显着差异。髋部骨折发生率保持稳定,LOS减少,这可能是由于最近的部门变动以及大流行期间患者快速出院的驱动。我们同意现有的报道,即老年髋部骨折患者感染COVID-19的围手术期死亡率更高,然而,我们的研究结果表明,整个髋部骨折患者的总死亡率与前一年相似,其中死亡更常见的原因是与其他病原体相关的呼吸道感染。由于病毒和条件的突变可能影响结果,可能需要进一步开展工作来评估大流行随后几波期间的结果。
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引用次数: 5
Patient-Reported Symptoms after Midfacial Trauma. 患者报告的中面部创伤后症状。
IF 0.9 Pub Date : 2022-01-17 eCollection Date: 2022-01-01 DOI: 10.1055/s-0041-1742174
Nina Pauli, Martina Grinups, Lena Folkestad, Gunnhildur Gudnadottir

Background  The aim of this study was to assess patient-reported symptoms and health-related quality of life, 12 to 24 months after injury in patients with midfacial fractures. Methods  Patients diagnosed with midfacial fractures were assessed regarding symptoms related to the fracture as well as assessment of the patients overall health-related quality of life using the Gothenburg Trismus Questionnaire (GTQ), the Folkestad facial trauma questionnaire, and EuroQol five-dimensional (EQ-5D). Questionnaires were distributed to the study patients 12 to 24 months after the trauma. Medical records were retrospectively surveyed for age, gender, trauma etiology, date of injury, fracture classification, treatment regimen, and time of surgery. Results  Sixty-seven percent of the study group reports sensibility disturbance in the face 12 to 24 months after trauma and 52% reported cosmetic consequences related to the trauma. Numbness in the face was the symptom reported to be most disturbing for the patients. Few of the patients reported severe jaw-related problems, problems with muscular tension, or eating limitation according to the validated questionnaire GTQ. Conclusion  Sensibility disturbance remains a significant and common symptom 12 to 24 months after midfacial trauma. There is a need for a validated patient-reported outcome instrument for facial trauma that covers multiple aspects of facial trauma such as vision disturbance and diplopia, jaw-related problems, and facial pain as well as sensibility disturbance and cosmetic consequences.

本研究的目的是评估面中骨折患者损伤后12至24个月患者报告的症状和与健康相关的生活质量。方法采用Gothenburg Trismus问卷(GTQ)、Folkestad面部创伤问卷(Folkestad facial trauma Questionnaire)和EuroQol五维量表(EQ-5D)对确诊为面中骨折的患者进行骨折相关症状和总体健康相关生活质量评估。调查问卷在创伤后12至24个月分发给研究患者。回顾性调查患者的年龄、性别、创伤病因、损伤日期、骨折分类、治疗方案和手术时间。结果67%的研究组报告创伤后12 ~ 24个月出现面部敏感性障碍,52%的研究组报告与创伤相关的美容后果。据报道,面部麻木是患者最不安的症状。根据验证问卷GTQ,很少有患者报告严重的下颌相关问题,肌肉紧张问题或进食限制。结论颜面中外伤后12 ~ 24个月仍有明显的敏感性障碍。需要一种经过验证的面部创伤患者报告的结果工具,涵盖面部创伤的多个方面,如视力障碍和复视,颌骨相关问题,面部疼痛以及敏感性障碍和美容后果。
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引用次数: 1
Minimally Invasive Successful Reconstruction of a Severely Traumatized Upper Extremity Using Platelet-Rich Plasma and Tissue Scaffold: A Case Report. 应用富血小板血浆和组织支架成功微创重建严重创伤上肢1例。
IF 0.9 Pub Date : 2022-01-17 eCollection Date: 2022-01-01 DOI: 10.1055/s-0041-1742176
Srinjoy Saha

Minimally invasive reconstruction combines principles of tissue engineering and regenerative medicine for healing complex wounds. This approach was successfully demonstrated on a 64-year-old diabetic and hypertensive male patient, who was brought unconscious to our emergency after surviving an automobile collision with severe brain and right-dominant upper extremity injuries. Uncontrolled hyperglycemia, severe anemia, diffuse axonal brain injury, wrist drop, and loss of thumb extension and abduction were noted. Extensive degloving, skin necrosis, extensor and flexor forearm muscle crush injuries, and ruptured extensor tendons were observed. Serial wound debridement combined with platelet-poor plasma injection into the muscles, platelet-rich plasma injections into the tendons and subcutis, and low-negative pressure wound therapy were performed sequentially to salvage the injured soft-tissues. Improvements were noticed during the second exploration after 5 days. Surviving muscles showed adequate vascularization and revival of innervation during the third exploration after another 5 days. Thereafter, absorbable synthetic tissue scaffold was applied over a sizeable 270 cm 2 wound as a flap-alternative. Tissues regenerated well within the scaffold during the next 2 months, halving the wound area to 132 cm 2 . A thick split-skin graft was applied over the remaining granulating neodermis, which "took" completely. Six months postoperatively, the patient regained most hand functions and performed all activities satisfactorily, while the grafted area appeared almost identical to surroundings. Minimally invasive reconstruction thus produced satisfying results with fewer shorter simpler surgeries, minimal anesthesia, short-duration hospitalization, lower health care costs, lesser risks, and excellent patient-reported outcomes.

微创重建结合了组织工程和再生医学的原理,用于治疗复杂的伤口。该方法在一名64岁的糖尿病和高血压男性患者身上得到了成功的证明,该患者在一次汽车碰撞中幸存下来,并伴有严重的脑部和右上肢损伤,随后被送往我们的急诊室。未控制的高血糖,严重贫血,弥漫性脑轴索损伤,手腕下垂,拇指伸展和外展丧失。大面积脱手套,皮肤坏死,前臂伸肌和屈肌挤压损伤,伸肌腱断裂。采用连续创面清创联合贫血小板血浆肌内注射、富血小板血浆肌腱及皮下注射、低负压创面治疗,抢救损伤软组织。在5天后的第二次探测中发现了改善。存活的肌肉在5天后的第三次探查中显示出充足的血管化和神经支配的恢复。此后,可吸收的合成组织支架应用于一个相当大的270 cm 2伤口作为皮瓣替代。在接下来的2个月里,组织在支架内再生良好,伤口面积减半至132平方厘米。将厚的裂皮移植物应用于剩余的肉芽状新生真皮,使其完全“吸收”。术后6个月,患者大部分手部功能恢复,活动满意,移植区与周围环境基本一致。因此,微创重建以更少、更简单的手术、最少的麻醉、较短的住院时间、较低的医疗费用、较小的风险和良好的患者报告结果产生了令人满意的结果。
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引用次数: 3
Intracranial Hemorrhage following Spinal Surgery: A Systematic Review of a Rare Complication 脊柱手术后颅内出血:一种罕见并发症的系统回顾
IF 0.9 Pub Date : 2022-01-01 DOI: 10.1055/s-0042-1743525
T. Al-Saadi, Yahya Al-Kindi, Moosa Allawati, H. Al-Saadi
Introduction  Intracranial hemorrhage (ICH) is a potentially severe complication of spinal surgeries. The occurrence of such complications causes deterioration of the patient's clinical status and delayed discharge from the hospital. Although no specific etiological factors were identified for this complication, but multiple risk factors might play role in its development, they include the use of anticoagulants, presence of uncontrolled hypertension, and perioperative patient positioning. Aim  A systematic review of the literature to investigate the prevalence of different types of intracranial hemorrhages in patients who underwent spinal surgeries. Methods  A literature review was conducted using multiple research databases. Data were extracted using multiple variables that were formulated incongruent with the study aim and then further analyzed. Results  A total of 79 studies were included in our analysis after applying the exclusion criteria and removing of repeated studies, 109 patients were identified where they were diagnosed with intracranial hemorrhage after spine surgery with a mean age of 54 years. The most common type of hemorrhage was cerebellar hemorrhage (56.0%) followed by SDH and intraparenchymal hemorrhage; 23.9 and 17.4%, respectively. The most common spine surgery was laminectomy (70.6%), followed by fixation and fusion (50.5%), excision of spinal lesions was done in 20.2% of the patient, and discectomy (14.7%). Conclusion  The data in this study showed that out of 112 patients with ICH, cerebellar hemorrhage was the most common type. ICH post–spine surgery is a rare complication and the real etiologies behind this complication are still unknown, cerebrospinal fluid drain and durotomy were suggested.
介绍 颅内出血(ICH)是脊柱手术中一种潜在的严重并发症。此类并发症的发生会导致患者的临床状况恶化并延迟出院。尽管没有确定这种并发症的具体病因,但多种风险因素可能在其发展中发挥作用,包括抗凝血剂的使用、高血压失控的存在以及围手术期患者的定位。目标 对文献的系统回顾,以调查接受脊柱手术的患者中不同类型颅内出血的患病率。方法 使用多个研究数据库进行了文献综述。使用与研究目标不一致的多个变量提取数据,然后进行进一步分析。后果 在应用排除标准并删除重复研究后,共有79项研究被纳入我们的分析,109名患者在脊柱手术后被诊断为颅内出血,平均年龄为54岁。最常见的出血类型是小脑出血(56.0%),其次是SDH和脑实质内出血;分别为23.9%和17.4%。最常见的脊柱手术是椎板切除术(70.6%),其次是固定融合术(50.5%),20.2%的患者进行了脊柱病变切除术,14.7%的患者接受了椎间盘切除术 本研究的数据显示,在112例脑出血患者中,小脑出血是最常见的类型。ICH脊柱后手术是一种罕见的并发症,这种并发症背后的真正病因尚不清楚,建议进行脑脊液引流和硬膜切开术。
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引用次数: 2
Delayed Granulomas as a Complication Secondary to Lip Augmentation with Dermal Fillers: A Systematic Review 延迟性肉芽肿是用真皮填充物隆唇后继发的并发症:一项系统综述
IF 0.9 Pub Date : 2022-01-01 DOI: 10.1055/s-0042-1743524
L. Trinh, Kelly C McGuigan, Amar Gupta
Introduction  Lip augmentation with dermal filler is rising in popularity. There are generally minimal side effects that are mild and transient. However, long-term complications may occur and include lumps, bumps, nodules, or granulomas. To better understand this uncommon but challenging outcome, we aim to perform a thorough systematic review of the published literature related to nodule or granuloma formation after cosmetic soft tissue augmentation of the lips. Methods  A search of published literature was conducted in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines in April 2021 and included PubMed, ScienceDirect, Embase, Google Scholar, and Cochrane databases. The Medical Subject Headings (MeSH) terms used included the following terms: “lip filler,” “hyaluronic acid,” “lip injection,” “lip augmentation,” “silicone,” “poly-L-lactic acid,” “calcium hydroxyapatite,” “polymethylmethacrylate,” “complications,” “reaction,” “granuloma,” and “nodule.” All studies were reviewed by two independent reviewers. Any discrepancies were resolved by a third reviewer. Results  The initial search for filler-related nodules or granulomas yielded 2,954 articles and 28 were included in the final analysis containing 66 individual cases of lip nodules. All but one patient was female. The mean age was 50 years. Nodules presented on average 35.2 months or 2.9 years after initial treatment. Thirty-seven nodules underwent histological analysis, the majority of which identified the presence of a foreign-body granuloma. Silicone was the most reported filler used followed by hyaluronic acid. Most cases resolved following multiple treatments including oral antibiotics or steroids followed by surgical excision. Conclusion  Understanding the sequelae of lip augmentation with filler products allows clinicians to provide safe and effective treatment. Nodules that present months to years following dermal treatment may represent a foreign-body granuloma. A combination of oral antibiotics, intralesional or oral steroids, and surgical excision successfully treated the majority of cases in our study.
介绍 用真皮填充物隆唇越来越受欢迎。一般来说,副作用很小,是轻微和短暂的。然而,可能会出现长期并发症,包括肿块、肿块、结节或肉芽肿。为了更好地理解这种不常见但具有挑战性的结果,我们旨在对已发表的与唇部美容软组织增强术后结节或肉芽肿形成相关的文献进行彻底的系统综述。方法 2021年4月,根据PRISMA(系统评价和荟萃分析的首选报告项目)指南对已发表的文献进行了搜索,包括PubMed、ScienceDirect、Embase、Google Scholar和Cochrane数据库。使用的医学主题标题(MeSH)术语包括以下术语:“唇部填充物”、“透明质酸”、“唇部注射”、“隆唇”、“硅胶”、“聚-L-乳酸”、“羟基磷灰石钙”、“聚甲基丙烯酸甲酯”、“并发症”、“反应”、“肉芽肿”和“结节”。所有研究均由两名独立评审员进行评审。任何差异都由第三位评审员解决。后果 对填充物相关结节或肉芽肿的初步搜索产生了2954篇文章,28篇被纳入最终分析,包含66例唇结节。除一名患者外,其余均为女性。平均年龄为50岁。结节在初次治疗后平均出现35.2个月或2.9年。37个结节接受了组织学分析,其中大多数确定存在异物肉芽肿。硅胶是使用最多的填充剂,其次是透明质酸。大多数病例在多种治疗后得到解决,包括口服抗生素或类固醇,然后进行手术切除。结论 了解填充产品隆唇的后遗症可以让临床医生提供安全有效的治疗。真皮治疗后数月至数年出现的结节可能代表异物肉芽肿。在我们的研究中,口服抗生素、病灶内或口服类固醇以及手术切除的组合成功地治疗了大多数病例。
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引用次数: 7
Intravenous Foreign Body at the Hand: Case Report 手部静脉异物:1例报告
IF 0.9 Pub Date : 2022-01-01 DOI: 10.1055/s-0042-1743522
J. Couceiro, Elena Garcia-Valladares, J. Fernandez-Divar, M. Sánchez-Crespo, H. Ayala, Fernanado Del Canto
Intravenous foreign bodies following trauma to the hand are relatively uncommon with sparse reports of this condition being published in the literature. They have been reported to migrate as far as the thoracic cavity and the heart. In the following case report, we describe a case of an intravenous foreign body following hand trauma, and the treatment and potential complications are also discussed.
手部外伤后静脉内异物相对不常见,文献中发表的这种情况的报道很少。据报道,它们可以迁移到胸腔和心脏。在以下病例报告中,我们描述了一例手部外伤后静脉异物的病例,并讨论了治疗和潜在的并发症。
{"title":"Intravenous Foreign Body at the Hand: Case Report","authors":"J. Couceiro, Elena Garcia-Valladares, J. Fernandez-Divar, M. Sánchez-Crespo, H. Ayala, Fernanado Del Canto","doi":"10.1055/s-0042-1743522","DOIUrl":"https://doi.org/10.1055/s-0042-1743522","url":null,"abstract":"Intravenous foreign bodies following trauma to the hand are relatively uncommon with sparse reports of this condition being published in the literature. They have been reported to migrate as far as the thoracic cavity and the heart. In the following case report, we describe a case of an intravenous foreign body following hand trauma, and the treatment and potential complications are also discussed.","PeriodicalId":44614,"journal":{"name":"Surgery Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46493720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cecal Bascule in a COVID-19 Positive Patient: Case Report 一例新冠肺炎阳性患者的Cecal Bascule病例报告
IF 0.9 Pub Date : 2022-01-01 DOI: 10.1055/s-0042-1743527
Arthur Curmi, Robert Cuschieri
Cecal volvulus is an uncommon cause of acute intestinal obstruction accounting for around 10% of intestinal volvuli. There are three main variants of cecal volvuli including the axial, loop, and bascule types. Diagnosis is confirmed via a computed tomography scan and surgery is the mainstay treatment due to a high risk of morbidity and mortality. Here we report a rare presentation of cecal volvulus in a COVID-19 positive patient that was complicated by an anastomotic leak.
盲肠扭转是一种罕见的急性肠梗阻的原因,约占肠扭转的10%。盲肠扭转有三种主要的变异,包括轴型、环型和束型。诊断通过计算机断层扫描确认,由于发病率和死亡率高,手术是主要的治疗方法。在这里,我们报告一例罕见的新冠病毒阳性患者的盲肠扭转,并伴有吻合口瘘。
{"title":"Cecal Bascule in a COVID-19 Positive Patient: Case Report","authors":"Arthur Curmi, Robert Cuschieri","doi":"10.1055/s-0042-1743527","DOIUrl":"https://doi.org/10.1055/s-0042-1743527","url":null,"abstract":"Cecal volvulus is an uncommon cause of acute intestinal obstruction accounting for around 10% of intestinal volvuli. There are three main variants of cecal volvuli including the axial, loop, and bascule types. Diagnosis is confirmed via a computed tomography scan and surgery is the mainstay treatment due to a high risk of morbidity and mortality. Here we report a rare presentation of cecal volvulus in a COVID-19 positive patient that was complicated by an anastomotic leak.","PeriodicalId":44614,"journal":{"name":"Surgery Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48079175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stentolith in Bile Duct: A Neglected Entity—Case Report with Review of Literature 胆管支架:一个被忽视的实体-病例报告并文献复习
IF 0.9 Pub Date : 2022-01-01 DOI: 10.1055/s-0042-1743521
Amit Gupta, D. Rajput, J. Chennat, Tanuj Singla, Shaik Sameer Ahmed
Stentolith is a forgotten stent that acts as a nidus for stone formation leading to a stone-stent complex. Once the planned procedure is completed, these stents should be removed within 4 to 6 weeks, but if they are required for a longer period, then they should be replaced every 3 to 6 months. Devastating complications may ensue —such as cholangitis, biliary stricture, or secondary biliary cirrhosis. Management primarily comprises surgical intervention with common bile duct exploration or endoscopic clearance. The majority of patients eventually develop symptoms that lead to their diagnosis and subsequent management. This article, however, details the case of a silent stentolith and how it may have led to disastrous complications if surgical intervention was not done promptly.
支架是一种被遗忘的支架,它作为结石形成的中心,导致结石支架复合物。一旦计划的手术完成,这些支架应在4至6周内取出,但如果需要更长时间,则应每3至6个月更换一次。毁灭性的并发症可能随之而来,如胆管炎、胆道狭窄或继发性胆汁性肝硬化。治疗主要包括手术干预和胆总管探查或内镜清理。大多数患者最终会出现导致诊断和后续治疗的症状。这篇文章,然而,详细的情况下,沉默的支架和它如何可能导致灾难性的并发症,如果不及时进行手术干预。
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引用次数: 0
Comparison of LRINEC Scoring System with Finger Test and Histopathological Examination for Necrotizing Fasciitis. LRINEC评分系统与指检及组织病理学检查对坏死性筋膜炎的比较。
IF 0.9 Pub Date : 2022-01-01 DOI: 10.1055/s-0041-1740629
Farah Naaz Kazi, J V Sharma, Shaurav Ghosh, D Prashanth, V Om Pramod Kumar Raja

Background  Necrotizing fasciitis (NF) is a life-threatening condition requiring urgent attention. It is clinically difficult to diagnose, linked to severe systemic toxicity, and has poor prognosis. In 2001, Andreasen and coworkers described the "Finger test" for the diagnosis of NF. Subsequent studies have suggested early recognition and management of NF. In this study, we compare the LRINEC-Laboratory Risk Indicator for Necrotizing Fasciitis-scoring system with the "Finger test" and histopathological examination for diagnosis of NF. Results  In our study, LRINEC scoring system and Finger test are statistically significant in the diagnosis of NF. Males are more frequently affected, and the most common organism causing NF is Staphylococcus . Histopathology remained the gold standard for diagnosis of NF, while LRINEC score and Finger test were good diagnostic tools for early diagnosis, with sensitivities of 83.33 and 86.11%, respectively. Conclusion  LRINEC laboratory-based scoring system is easy and reliable diagnostic tool though histopathology remains the gold standard. There is statistically significant correlation between histopathology and laboratory criteria. LRINEC test is independently better than bedside Finger test alone or combined LRINEC and bedside Finger test.

背景:坏死性筋膜炎(NF)是一种危及生命的疾病,需要紧急关注。临床上难以诊断,与严重的全身毒性有关,预后差。2001年,Andreasen和同事描述了诊断NF的“手指测试”。随后的研究提示了NF的早期识别和管理。在这项研究中,我们比较了lrinec -实验室风险指标坏死性筋膜炎评分系统与“手指试验”和组织病理学检查诊断NF。结果在本研究中,LRINEC评分系统和Finger检验对NF的诊断具有统计学意义。男性更容易感染,最常见的细菌是葡萄球菌。组织病理学仍然是诊断NF的金标准,LRINEC评分和Finger试验是早期诊断的良好诊断工具,敏感性分别为83.33%和86.11%。结论LRINEC实验室评分系统是简便可靠的诊断工具,但组织病理学仍是金标准。组织病理学和实验室标准有统计学上显著的相关性。LRINEC测试单独优于床边手指测试或LRINEC与床边手指测试联合。
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引用次数: 2
Current Approach for Diagnosis and Treatment of Adrenal Tuberculosis—Our Experience and Review of Literature 肾上腺结核的诊断和治疗方法——经验与文献复习
IF 0.9 Pub Date : 2022-01-01 DOI: 10.1055/s-0042-1743523
Stuti Gupta, Md. Abu Masud Ansari, Arun Gupta, P. Chaudhary, L. Bansal
Addison's disease was first described by Thomas Addison in 1855. He demonstrated the destruction of bilateral adrenal gland by tuberculosis (TB) in six patients. Since then, the incidence of TB has declined in the Western world, but in developing countries, it is still the most common cause of adrenal insufficiency. Because of the introduction of antituberculous chemotherapy, the incidence of adrenal TB has been declined in the past decades. The most common symptoms are nonspecific; therefore, diagnosis is often delayed, and patients may first present with a life-threatening adrenal crisis. The most commonly identified organism for adrenal failure in adrenal TB is Mycobacterium tuberculosis infection. Adrenal TB involves bilateral adrenal glands more frequently than unilateral glands. Computed tomography (CT) scan and magnetic resonance imaging (MRI) are useful investigations to differentiate between tuberculous Addison's disease and the other causes of adrenal insufficiency. In CT scans or MRI, features of adrenal TB are bilateral adrenal enlargement and peripheral rim enhancement with or without calcifications. Antituberculous drugs, biochemical monitoring of adrenal function, and steroid therapy are essential for the management of adrenal TB and adrenal insufficiency. Here, we describe a case of adrenal TB with abscess formation followed by a review of the current literature of adrenal TB for better diagnosis and management of this condition.
托马斯·艾迪生于1855年首次描述了艾迪生病。他在6名患者中证实了肺结核对双侧肾上腺的破坏。从那时起,结核病的发病率在西方世界有所下降,但在发展中国家,它仍然是肾上腺功能不全的最常见原因。由于抗结核化疗的引入,肾上腺结核的发病率在过去几十年中有所下降。最常见的症状是非特异性的;因此,诊断往往会延迟,患者可能首先出现危及生命的肾上腺危象。肾上腺结核肾上腺功能衰竭最常见的病因是结核分枝杆菌感染。肾上腺结核涉及双侧肾上腺的频率高于单侧肾上腺。计算机断层扫描(CT)和磁共振成像(MRI)是区分结核性艾迪生病和其他肾上腺功能不全原因的有用研究。在CT扫描或MRI中,肾上腺结核的特征是双侧肾上腺增大和外周边缘增强,伴有或不伴有钙化。抗结核药物、肾上腺功能的生化监测和类固醇治疗对治疗肾上腺结核和肾上腺功能不全至关重要。在此,我们描述了一例肾上腺结核伴脓肿形成的病例,然后回顾了目前肾上腺结核的文献,以更好地诊断和治疗这种情况。
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引用次数: 3
期刊
Surgery Journal
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