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Bilateral eagle syndrome: A rare entity 双侧鹰综合征:罕见的疾病
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-04-19 DOI: 10.1177/20101058231172233
Abdul Azim Al-Abrar Ahmad Kailani, Muhammad Ariff Sobani, Noor Shairah Mat Barhan, Norazila Abdul Rahim, M. Mansor, N. Lazim
Elongated styloid process or Eagle syndrome is a rare condition presenting with a wide range of symptoms including throat pain, foreign body sensation, neck pain, and ear pain. Establishing a diagnosis requires a high index of suspicion and understanding of this entity by the physician. Computed tomography (CT) is the gold standard to diagnose Eagle syndrome. Conservative medical treatment with analgesics, oral steroids, and anticonvulsants are offered in patients who refused surgery. The mainstay of treatment is surgical resection through transoral or transcervical approaches. We describe a rare case of bilateral Eagle syndrome which presented with chronic foreign body sensation in the throat but aggravated by fish bone ingestion. Flexible nasopharyngolaryngoscopy (FNPLS) and cervical x-ray did not reveal any foreign body but showed an incidental finding of elongated styloid process bilaterally. Contrast-enhanced CT scan of the neck confirmed the finding of the elongated styloid process bilaterally. The patient underwent transoral endoscopic assisted bilateral styloidectomy following tonsillectomy. There was complete resolution of the symptoms during postoperative follow-up. This approach is recommended to avoid external scarring, minimize postoperative pain, and shorter hospital stay.
茎突拉长或Eagle综合征是一种罕见的疾病,表现为广泛的症状,包括喉咙痛、异物感、颈部疼痛和耳痛。建立诊断需要医生对该实体的高度怀疑和理解。计算机断层扫描(CT)是诊断Eagle综合征的金标准。对于拒绝手术的患者,保守治疗包括止痛剂、口服类固醇和抗惊厥药。主要的治疗方法是经口或经颈入路手术切除。我们描述了一个罕见的病例双侧鹰综合征,其表现为慢性异物感在喉咙,但加重了鱼骨摄入。柔性鼻咽喉镜检查(FNPLS)和颈部x线检查未发现任何异物,但偶然发现双侧茎突延长。颈部CT增强扫描证实双侧茎突延长。患者在扁桃体切除术后行经口内镜辅助双侧茎突切除术。术后随访症状完全消失。这种方法可以避免外部瘢痕,减少术后疼痛,缩短住院时间。
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引用次数: 0
Perspectives of Singaporean Chinese patients with mild dementia and their family caregivers towards end-of-life care: Results from a qualitative study 新加坡华人轻度痴呆患者及其家庭照顾者对临终关怀的展望:一项定性研究的结果
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-03-31 DOI: 10.1177/20101058231167252
Dennis Seow, Amanda Pang, S. Ho, Chetna Malhotra
Currently, there is little understanding of how patients with dementia and their caregivers view end-of-life (EOL) care. We thus aimed to study and understand the perception of EOL care by patients with mild dementia and their family caregivers. We conducted qualitative in-depth interviews with 25 patients with mild dementia and their family caregivers belonging to Chinese ethnicity in Singapore. Patients’ and family caregivers’ understanding of illness, patients’ preferences for EOL care and caregiver concerns for the patients were discussed. Thematic analysis was conducted on the transcribed results of the interviews. We identified three main themes of person-centred EOL care: planning for cognitive decline and death, supporting patients to die peacefully at home, and supporting family caregivers to cope with patient’s condition. Most patients wanted to die peacefully and be cared for at their home. However, they were reluctant to initiate discussions regarding their future health care and seemed to be in denial that they may decline cognitively in future. Caregiver burden was noticeable for all family caregivers interviewed. . Results highlight three important components that would enhance the delivery of patient-centred EOL care in patients with mild dementia. Strategies based on these components can enable family caregivers and health care providers to plan for and provide patient-centred EOL care concordant with patients’ wishes.
目前,人们对痴呆症患者及其护理人员如何看待临终关怀(EOL)知之甚少。因此,我们旨在研究和了解轻度痴呆患者及其家庭照顾者对EOL护理的看法。我们对新加坡的25名轻度痴呆患者及其家庭照顾者进行了定性深入访谈。讨论了患者及其家属对疾病的理解、患者对EOL护理的偏好以及护理者对患者的关注。对访谈记录的结果进行了专题分析。我们确定了以人为本的EOL护理的三个主要主题:对认知能力下降和死亡的规划,支持患者在家中平静地死去,以及支持家庭照顾者应对患者的病情。大多数病人希望平静地死去,在家中得到照顾。然而,他们不愿意开始讨论他们未来的医疗保健,似乎否认他们未来可能会下降的认知能力。所有接受采访的家庭照顾者都有明显的照顾者负担。结果突出了三个重要组成部分,将加强以患者为中心的轻度痴呆患者EOL护理的交付。基于这些组成部分的战略可以使家庭照顾者和卫生保健提供者能够规划并提供符合患者意愿的以患者为中心的EOL护理。
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引用次数: 0
Recreational cycling related injuries at the emergency department 在急诊科的休闲自行车相关伤害
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-03-30 DOI: 10.1177/20101058231167245
Jia Rui Kwan, Shiun-Hwa Chantal Lim, Wei Lin Lester Ong, Yong Hui Alvin Tan, J. Kam, J. Pek
Recreational cycling is gaining popularity in Singapore but there is a lack of literature regarding the spectrum and severity of these injuries and their impact on the utilisation of healthcare resources. We aim to characterise these injuries, as well as to review the healthcare resources required by injured cyclists. A retrospective review of patients with recreational cycling-related injuries presenting to the Emergency Department (ED) between August 2018 and December 2020 was performed. Information about demographics, circumstances of injury, injuries sustained, clinical progress, and outcomes were collected and analysed. There were 214 patients, with an increase in monthly attendance towards the end of the study period. The median age was 48 years old (interquartile range (IQR) 31 to 60) and 165 (77.1%) patients were male. In the ED, 35 (16.4%), 142 (66.4%), and 37 (17.3%) patients were triaged as P1 (emergent), P2 (urgent), and P3 (ambulatory) respectively. Blunt injuries occurred in 210 (98.1%) patients. Soft tissue injuries involving the upper and lower limbs were most common. One hundred and eighty-one (84.6%) patients had a minor to moderate injury classified by an Injury Severity Score of 0 to 8. One hundred twenty-four (57.9%) patients were admitted to the hospital with 40 (18.7%) requiring surgery. Recreational cycling-related injuries are increasingly encountered in the ED. These injuries are associated with morbidities which require utilisation of healthcare resources. Legislation and education efforts to promote safety in recreational cycling are required to reduce accidents and minimise the impact of the injuries sustained.
休闲自行车在新加坡越来越受欢迎,但缺乏关于这些损伤的范围和严重程度及其对医疗资源利用的影响的文献。我们的目标是描述这些伤害的特征,并审查受伤自行车手所需的医疗资源。对2018年8月至2020年12月期间急诊科就诊的娱乐性自行车相关损伤患者进行了回顾性审查。收集并分析了有关人口统计、受伤情况、所受伤害、临床进展和结果的信息。共有214名患者,在研究期结束时,每月就诊人数有所增加。中位年龄为48岁(四分位间距(IQR)31至60),165名(77.1%)患者为男性。在急诊科,35名(16.4%)、142名(66.4%)和37名(17.3%)患者分别被分为P1(急诊)、P2(急诊)和P3(门诊)。钝性损伤210例(98.1%)。上肢和下肢软组织损伤最为常见。一百八十一名(84.6%)患者有轻度至中度损伤,损伤严重程度评分为0至8。124名(57.9%)患者入院,其中40名(18.7%)患者需要手术治疗。ED中越来越多地遇到与休闲自行车相关的伤害。这些伤害与需要利用医疗资源的疾病有关。需要立法和教育努力促进休闲自行车的安全,以减少事故并将受伤的影响降至最低。
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引用次数: 0
The effect of fine-particle size and extrafine particle size inhaled corticosteroid in reducing airway resistance in asthmatic patients 细颗粒和细颗粒吸入皮质类固醇对降低哮喘患者气道阻力的影响
Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-03-29 DOI: 10.1177/20101058231167250
Mohamed Faisal Abdul Hamid, Asyraf Ahmad, Mas Fazlin Mohamad Jailaini, Shahrul Aiman Soelar, Nik Nuratiqah Nik Abeed, Ng Boon Hau, Azat Azrai Azmel, Andrea Ban
Background Bronchial asthma is characterised by chronic inflammation of both large and small airways. Extra-fine formulation of inhaled corticosteroid (ICS) can achieve a higher peripheral lung deposition leading to improved asthma control. We investigated the effect of extra-fine and fine particle size inhaled ICS with airway resistance and severity of symptoms in asthmatic patients. Methods Prospective interventional study of outpatient asthmatics in Universiti Kebangsaan Malaysia Medical Centre (UKMMC). Subjects were grouped based on pre-existing inhalers; extra-fine and fine inhaled corticosteroid (ICS)/long acting beta agonist (LABA). Crossover was at week 7 and treatment regime continued for 7 weeks. Subjects were assessed at week 0, 6 and 13 using asthma control test (ACT) score, forced expiratory volume in 1 s (FEV 1 ) and impulse oscillometry (IOS) Inhaler technique was assessed periodically. Results Thirty-four subjects were recruited. Median asthma duration was 20 years. Twenty subjects (58%) in fine ICS/LABA and 14 (42%) in extra-fine ICS/LABA group. Thirty-one subjects were analysed before crossver. There was a significant improvement of FEV 1 in the extra-fine ICS/LABA group (1.7 ± 0.47 to 1.88 ± 0.5; p = 0.01). ACT score reduced significantly in extra-fine ICS/LABA group (23 ± 5 to 21 ± 4; p = 0.04) at week 0–6. Week 7–13 showed a significant improvement of ACT score (16.5 ± 3 to 20 ± 3; p = 0.01) and FEV1 (1.71 ± 0.96 to 1.81 ± 1.02: p = 0.01) in extra-fine ICS/LABA. There was no significant difference in (IOS) parameters between the groups. Conclusion There was an improvement of FEV 1 and ACT score with extra-fine ICS/LABA with no benefit in airway resistance.
支气管哮喘的特点是大气道和小气道的慢性炎症。吸入皮质类固醇(ICS)的超精细配方可以实现更高的外周肺沉积,从而改善哮喘控制。我们探讨超细和细颗粒吸入ICS对哮喘患者气道阻力和症状严重程度的影响。方法对马来西亚Kebangsaan大学医学中心门诊哮喘患者进行前瞻性介入研究。受试者根据已有吸入器进行分组;超细和细吸入皮质类固醇(ICS)/长效受体激动剂(LABA)。在第7周进行交叉,治疗方案持续7周。于第0、6和13周采用哮喘控制试验(ACT)评分、1 s用力呼气量(FEV 1)和脉冲振荡法(IOS)定期评估受试者吸入器技术。结果共招募34名受试者。中位哮喘持续时间为20年。细ICS/LABA组20例(58%),超细ICS/LABA组14例(42%)。31名受试者在交叉前进行了分析。超细ICS/LABA组FEV 1明显改善(1.7±0.47 ~ 1.88±0.5);P = 0.01)。超微ICS/LABA组ACT评分明显降低(23±5 ~ 21±4);P = 0.04)。第7-13周ACT评分显著提高(16.5±3 ~ 20±3);p = 0.01)和FEV1(1.71±0.96 ~ 1.81±1.02:p = 0.01)。两组间(IOS)参数差异无统计学意义。结论超细ICS/LABA可改善FEV 1和ACT评分,但对气道阻力无改善作用。
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引用次数: 0
Project SAPPORO (StAff prescription – bluPORt optimization): Quality improvement report on the expanded use of secured medication lockers for hospital staff during COVID-19 pandemic 札幌项目(工作人员处方- bluPORt优化):关于COVID-19大流行期间医院工作人员扩大使用安全储药柜的质量改进报告
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-03-27 DOI: 10.1177/20101058231167258
Zhi Yang Neo, E. Foo, Li Xian Ng, Yao Hui Poh
Background Singapore General Hospital (SGH) Pharmacy department set up a novel 24-h medication locker service in November 2019 to serve hospital staff on work shifts who were unable to collect medication within the pharmacy operating hours. However, the initial uptake rate was modest. Objectives Primary objective was to increase the daily locker service uptake by staff from five lockers to 42 lockers (100%) in 6 months, starting from June 2020. Secondary objectives include exploring the cost savings and impact of the locker service on the pharmacy’s operational efficiency, as well as compare the medication collection experience of hospital staff using the locker service and in the pharmacy. Methods FOCUS-PDSA was the adopted QI methodology. Two Plan-Do-Study-Act (PDSA) cycles were used to implement the final identified solutions. PDSA cycle one focused on improving publicity and educational efforts. PDSA cycle two then focused on expanding the service to include the entire hospital campus staff and setting up a self-registration booth at the pharmacy entrance. Results The primary objective of achieving 100% locker utilization was attained in October 2020, with daily average service uptake rate increasing from 12.6 at baseline to 49.8 by the end of PDSA cycle 2. Annual pharmacist manpower savings of 0.88 Full Time Equivalent (FTE) was also achieved. Locker service users gave a higher average satisfaction score compared to those who collected from the pharmacy. Conclusion Project SAPPORO successfully increased the daily locker service, providing hospital campus staff with increased convenience and positive medication collection experience during the COVID-19 pandemic.
背景2019年11月,新加坡总医院(SGH)药剂科推出了一项全新的24小时药物储物柜服务,为轮班的医院工作人员提供服务,这些工作人员无法在药房营业时间内取药。然而,最初的吸收率是适度的。主要目标是从2020年6月开始,在6个月内将员工每天使用的储物柜数量从5个增加到42个(100%)。次要目标包括探索储物柜服务对药房运营效率的成本节约和影响,以及比较医院工作人员使用储物柜服务和在药房取药的经验。方法FOCUS-PDSA采用QI方法学。两个计划-执行-研究-行动(PDSA)循环用于实施最终确定的解决方案。PDSA第一个周期的重点是改善宣传和教育工作。PDSA第二阶段的重点是将服务范围扩大到整个医院的员工,并在药房入口处设立一个自助登记亭。结果2020年10月实现了100%储物柜利用率的主要目标,到PDSA周期2结束时,每日平均服务使用率从基线时的12.6上升到49.8。药剂师每年可节省0.88全职当量的人力。储物柜服务用户的平均满意度高于药房用户。SAPPORO项目成功增加了日常储物柜服务,为医院校园员工在COVID-19大流行期间提供了更多的便利和积极的药物收集体验。
{"title":"Project SAPPORO (StAff prescription – bluPORt optimization): Quality improvement report on the expanded use of secured medication lockers for hospital staff during COVID-19 pandemic","authors":"Zhi Yang Neo, E. Foo, Li Xian Ng, Yao Hui Poh","doi":"10.1177/20101058231167258","DOIUrl":"https://doi.org/10.1177/20101058231167258","url":null,"abstract":"Background Singapore General Hospital (SGH) Pharmacy department set up a novel 24-h medication locker service in November 2019 to serve hospital staff on work shifts who were unable to collect medication within the pharmacy operating hours. However, the initial uptake rate was modest. Objectives Primary objective was to increase the daily locker service uptake by staff from five lockers to 42 lockers (100%) in 6 months, starting from June 2020. Secondary objectives include exploring the cost savings and impact of the locker service on the pharmacy’s operational efficiency, as well as compare the medication collection experience of hospital staff using the locker service and in the pharmacy. Methods FOCUS-PDSA was the adopted QI methodology. Two Plan-Do-Study-Act (PDSA) cycles were used to implement the final identified solutions. PDSA cycle one focused on improving publicity and educational efforts. PDSA cycle two then focused on expanding the service to include the entire hospital campus staff and setting up a self-registration booth at the pharmacy entrance. Results The primary objective of achieving 100% locker utilization was attained in October 2020, with daily average service uptake rate increasing from 12.6 at baseline to 49.8 by the end of PDSA cycle 2. Annual pharmacist manpower savings of 0.88 Full Time Equivalent (FTE) was also achieved. Locker service users gave a higher average satisfaction score compared to those who collected from the pharmacy. Conclusion Project SAPPORO successfully increased the daily locker service, providing hospital campus staff with increased convenience and positive medication collection experience during the COVID-19 pandemic.","PeriodicalId":44685,"journal":{"name":"Proceedings of Singapore Healthcare","volume":"32 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42147266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perioperative acute kidney injury: Current knowledge and the role of anaesthesiologists 围手术期急性肾损伤:当前的知识和麻醉师的作用
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-03-15 DOI: 10.1177/20101058231163406
Ji Xing, Samuel Kent Neng Loh
Among the different types of perioperative organ injury, acute kidney injury (AKI) occurs frequently and is consistently associated with increased rates of mortality and mortality. Despite development of many clinical trials to assess perioperative interventions, reliable means to prevent or reverse AKI are still lacking. This narrative review discusses recent literature on modifiable risk factors, current approaches to prevention and potential directions for future research. A Pubmed search with the relevant keywords was done for articles published in the last 10 years. New insights into preoperative identification and optimisation, intraoperative strategies, including the choice of anaesthetic, haemodynamic and fluid management, have been made, with the aim of preventing perioperative AKI. A patient-centric multidisciplinary approach is essential to protect kidney function of patients going for surgery. Much can be done by anaesthesiologists perioperatively, to reduce the risk of development of AKI, especially in susceptible patients. There is a need for further multicentred trials to enhance the currently generic perioperative recommendations.
在不同类型的围手术期器官损伤中,急性肾损伤(AKI)发生频繁,并始终与死亡率和死亡率增加相关。尽管开展了许多临床试验来评估围手术期干预措施,但仍然缺乏预防或逆转AKI的可靠方法。这篇叙述性综述讨论了最近关于可改变的危险因素的文献,目前的预防方法和未来研究的潜在方向。在Pubmed上用相关关键词搜索了最近10年发表的文章。为了预防围手术期AKI,对术前识别和优化、术中策略(包括麻醉选择、血流动力学和流体管理)有了新的认识。以患者为中心的多学科方法对于保护手术患者的肾功能至关重要。麻醉医师围手术期可以做很多事情,以降低AKI发展的风险,特别是在易感患者中。需要进一步的多中心试验来加强目前通用的围手术期推荐。
{"title":"Perioperative acute kidney injury: Current knowledge and the role of anaesthesiologists","authors":"Ji Xing, Samuel Kent Neng Loh","doi":"10.1177/20101058231163406","DOIUrl":"https://doi.org/10.1177/20101058231163406","url":null,"abstract":"Among the different types of perioperative organ injury, acute kidney injury (AKI) occurs frequently and is consistently associated with increased rates of mortality and mortality. Despite development of many clinical trials to assess perioperative interventions, reliable means to prevent or reverse AKI are still lacking. This narrative review discusses recent literature on modifiable risk factors, current approaches to prevention and potential directions for future research. A Pubmed search with the relevant keywords was done for articles published in the last 10 years. New insights into preoperative identification and optimisation, intraoperative strategies, including the choice of anaesthetic, haemodynamic and fluid management, have been made, with the aim of preventing perioperative AKI. A patient-centric multidisciplinary approach is essential to protect kidney function of patients going for surgery. Much can be done by anaesthesiologists perioperatively, to reduce the risk of development of AKI, especially in susceptible patients. There is a need for further multicentred trials to enhance the currently generic perioperative recommendations.","PeriodicalId":44685,"journal":{"name":"Proceedings of Singapore Healthcare","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46907061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent rhinosporidiosis: A case report from Malaysia and review of literature 复发性鼻孢子虫病:马来西亚1例报告及文献复习
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-03-14 DOI: 10.1177/20101058231160606
T. K. Tong, I. Ismail, Nik M Yunus Mohammad, S. Yusoff, Afifulhadi M Sahri
Over the decades, rhinosporidiosis has remained an enigma. It is a recalcitrant disease caused by Rhinosporidium seeberi, primarily affecting the nasal cavity, conjunctiva, and less frequently involved sites, including skin, urethra, and others. We report a case of a local from Sabah who has presented with recurring symptoms of nasal obstruction and epistaxis for two decades. He had previously undergone multiple endoscopic excisional surgeries before receiving treatment at our centre. Otorhinolaryngeal examination revealed polypoidal masses occupying bilateral nasal cavities with a perforation of the nasal septum. He underwent surgical resection of the lesions, and the histopathological examination confirmed recurrent rhinosporidiosis. Due to its sporistatic effects, dapsone was chosen as the pharmacological treatment in this case. However, after a year of follow-up, he developed similar symptoms and the endoscopic findings, indicated a recurrence of the disease. The histopathological samples obtained during the repeated surgery for recurrent polypoidal masses, confirmed the diagnosis of rhinosporiodiosis. As the disease poses diagnostic and therapeutic challenges, clinicians should be prudent in establishing the diagnosis in non-endemic areas, such as Malaysia, and evaluating the possibility of recurrence.
几十年来,鼻孢子虫病一直是个谜。这是一种由seeberi鼻孢子虫引起的顽固性疾病,主要影响鼻腔、结膜和不太常见的受累部位,包括皮肤、尿道和其他部位。我们报告了一例来自沙巴的本地人,他在20年来反复出现鼻阻塞和鼻出血症状。在我们中心接受治疗之前,他曾接受过多次内窥镜切除手术。耳鼻喉检查显示双侧鼻腔有息肉状肿块,鼻中隔穿孔。他接受了病变的手术切除,组织病理学检查证实复发性鼻孢子虫病。由于其抑孢子作用,本例选用氨苯砜作为药物治疗。然而,经过一年的随访,他出现了类似的症状,内镜检查结果表明疾病复发。在反复手术治疗复发性息肉状肿块期间获得的组织病理学样本证实了鼻孢子虫病的诊断。由于该疾病带来了诊断和治疗方面的挑战,临床医生应谨慎地在马来西亚等非流行地区进行诊断,并评估复发的可能性。
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引用次数: 0
Multiple primary malignant tumours of lung and colorectal adenocarcinoma: A case report 肺和结肠腺癌的多原发性恶性肿瘤1例
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-03-08 DOI: 10.1177/20101058231163408
M. A. Ibrahim, Nuruliman Dashuki, Nor Qhairul Izzreen Mohd Noor, S. M. Rusli
Multiple primary malignant tumors of lung and colorectal incidence were extremely rare and in most cases, diagnosed incidentally. Due to its rarity, most physicians consider pulmonary lesions found in patients with a history of colorectal cancer as lung metastasis. To avoid misdiagnosis and treatment delays, it is critical to properly screen and explore for possible metastasis or the occurrence of a second primary tumor after a primary cancer has been diagnosed. We describe a 72-year-old woman who presented with rectal bleeding associated with altered bowel movement. Rectal biopsy revealed colon adenocarcinoma and subsequent CT scan showed sigmoid colon mass and right lower lobe lung mass with multiple mediastinal lymphadenopathies. Biopsies of the mediastinal lymph nodes also showed adenocarcinoma. PET/CT scans showed different SUVmax of lesions in the sigmoid colon and right lower lobe, which raised the possibility of separate colonic and lung primary tumors as opposed to colonic primary with lung metastasis. Further immunohistology studies confirmed separate primary lung tumor. These diagnoses facilitate the clinical approach and define treatment options for the patient.
多原发性肺部和结直肠恶性肿瘤的发病率极为罕见,在大多数情况下,是偶然诊断的。由于其罕见性,大多数医生认为在有结直肠癌癌症病史的患者中发现的肺部病变是肺转移。为了避免误诊和治疗延误,在诊断出原发性癌症后,正确筛查和探索可能的转移或第二原发性肿瘤的发生是至关重要的。我们描述了一位72岁的女性,她出现了与排便改变相关的直肠出血。直肠活检显示结肠腺癌,随后的CT扫描显示乙状结肠肿块和右下叶肺部肿块,伴有多发纵隔淋巴结病。纵隔淋巴结活检也显示腺癌。PET/CT扫描显示乙状结肠和右下叶病变的SUVmax不同,这增加了结肠和肺原发性肿瘤分离的可能性,而不是结肠原发性肺转移。进一步的免疫组织学研究证实了单独的原发性肺肿瘤。这些诊断有助于临床方法并确定患者的治疗方案。
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引用次数: 0
The role for cochlear implants in microtia and congenital aural atresia: A case report and a review of literature 人工耳蜗在先天性小耳聋和先天性耳锁中的作用:1例报告及文献复习
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-02-27 DOI: 10.1177/20101058231160603
W. L. Neo, B. Tan, Adam Ping Meng Tan, Olivia May Ling Wee, J. Thong
Sensorineural hearing loss resulting from microtia and aural atresia is rare due to different embryologic origins of the external and inner ear. Consequently, cochlear implants are seldom performed in patients with microtia and/or aural atresia. Herein we discuss an 8 year-old boy with congenital aural atresia and microtia who underwent cochlear implant surgery for profound hearing loss with good results. A literature review was performed and discussed. Pre-operative planning with high resolution computed tomography and facial nerve monitoring are crucial in identification and preservation of the facial nerve due to the high rate of aberrant anatomy. Careful incision placement is required particularly if pinna reconstruction is considered. Literature review highlighted various surgical approaches as well as different modalities used for intra-operative facial nerve monitoring. Only one patient had intra-operative complications. Cochlear implant is a viable solution in patients with external ear malformations and severe-profound sensorineural hearing loss. Adequate planning and counselling are essential due to the challenges that may occur in microtia and aural atresia.
由于外耳和内耳的胚胎起源不同,由小耳和闭耳引起的感音神经性听力损失是罕见的。因此,耳蜗植入很少用于小耳畸形和/或耳闭锁患者。我们在此讨论一位患有先天性耳闭锁和小耳症的8岁男孩,他接受人工耳蜗手术治疗重度听力损失,效果良好。进行了文献综述并进行了讨论。由于面神经解剖异常率高,术前计划与高分辨率计算机断层扫描和面神经监测对于识别和保存面神经至关重要。尤其考虑耳廓重建时,需要小心切口的放置。文献回顾强调了术中面神经监测的各种手术入路和不同方式。仅有1例患者出现术中并发症。人工耳蜗是外耳畸形和重度感音神经性听力损失患者的一种可行的解决方案。由于小耳症和耳闭锁可能出现的挑战,适当的规划和咨询是必不可少的。
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引用次数: 0
The functional impact of implantable hearing devices in patients with single-sided deafness 植入式助听器对单侧耳聋患者功能的影响
IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-02-27 DOI: 10.1177/20101058231160604
Sin Wai Lee, H. Yuen, D. Low, S. Kamath, K. Chua
Single-sided deafness (SSD) is associated with significant functional impairment such as listening speech in noise and localizing sound. To date, studies on the efficacy of CI and BCI for single-sided deafness are conflicting. Thus, the objective of our study was to describe and compare the functional outcomes between these devices. Thirteen subjects with SSD were prospectively recruited for our study. Six underwent CI and seven received BCI. Word recognition scores (WRS) and disease specific outcome measures were obtained pre-implantation, at 6, and 12 months. WRS improved both in quiet and in noise for CI and BCI recipients. On the contrary, CI recipients displayed improvement in Speech Spatial Quality (SSQ) scores. A decreasing trend of improvement in APHAB scores were observed for the BCI group. BCI recipients showed a significant improvement in WRS (in noise). Conversely, CI recipients showed a great improvement in SSQ scores. These preliminary findings suggest that true binaural hearing can only be restored with CI for better SSQ performance. However, BCIs could be recommended to a sub-group of patients, if listening to speech in noise is a priority.
单侧耳聋(SSD)与严重的功能损害有关,如在噪声中听语音和定位声音。到目前为止,关于CI和脑机接口治疗单侧耳聋的疗效的研究是相互矛盾的。因此,我们研究的目的是描述和比较这些设备之间的功能结果。本研究前瞻性招募了13名SSD受试者。6例接受CI,7例接受BCI。在植入前、6个月和12个月获得单词识别评分(WRS)和疾病特异性结果测量。对于CI和BCI接受者,WRS在安静和噪声方面都有所改善。相反,CI接受者在语音空间质量(SSQ)得分方面表现出改善。脑机接口组的APHAB评分呈下降趋势。脑机接口受试者的WRS(噪声)有显著改善。相反,CI受试者在SSQ评分方面有很大的改善。这些初步发现表明,只有通过CI才能恢复真正的双耳听力,以获得更好的SSQ性能。然而,如果优先听噪声中的语音,可以向一个子组患者推荐脑机接口。
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引用次数: 0
期刊
Proceedings of Singapore Healthcare
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