Journal of Oral and Maxillofacial Surgery Medicine and Pathology最新文献_第10页

Development of a surgical ciliated cyst after maxillary sinus floor augmentation for dental implants: A case report and review of the literature 上颌窦底增强术治疗种植牙后发生纤毛囊肿：一例报告及文献回顾

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Oral and Maxillofacial Surgery Medicine and Pathology

Pub Date : 2025-04-11 DOI: 10.1016/j.ajoms.2025.04.002

Hiroyuki Kano , Yusuke Kato , Satoko Fukui , Satoshi Maruyama , Tadaharu Kobayashi

The occurrence of s surgical ciliated cyst after maxillary sinus floor augmentation has been reported as a delayed and rare complication, although maxillary sinus floor augmentation is a proven and reliable technique for dental implants with a low incidence of postoperative complications. Here, we present a case of surgical ciliated cyst associated with maxillary sinus floor augmentation. A 71-year-old woman was referred to our clinic with a chief complaint of swelling and tenderness of the left palatal region. She had a history of dental implant treatment in the area at another clinic three years ago. Computerized tomography revealed a radiolucent area around the implant fixtures in the left upper molar region. Based on a clinical diagnosis of a maxillary cyst, the patient underwent enucleation of the cyst under general anesthesia. Histopathological findings of the surgical specimen revealed that the cyst was lined by nonkeratinized squamous epithelium and partially lined by ciliated pseudostratified columnar epithelium, and the cyst was ultimately diagnosed as a surgical ciliated cyst. In conclusion, the occurrence of a surgical ciliated cyst should be noted as a delayed complication of maxillary sinus floor augmentation, although its occurrence is extremely rare. To prevent the development of this cystic lesion, careful dissection of the maxillary sinus membrane from the bony surface is essential during maxillary sinus floor augmentation to minimize its damage and avoid its perforation.

虽然上颌窦底增强术是一种可靠的种植牙技术，术后并发症发生率低，但上颌窦底增强术后发生的手术纤毛囊肿是一种延迟且罕见的并发症。在此，我们报告一例手术睫状体囊肿合并上颌窦底增强术。一位71岁的妇女被转介到我们的诊所，主诉肿胀和压痛的左腭区域。三年前，她曾在该地区的另一家诊所接受过植牙治疗。计算机断层扫描显示在左侧上磨牙区种植固定体周围有一个透光区。根据上颌囊肿的临床诊断，患者在全身麻醉下接受了囊肿摘除手术。手术标本的组织病理学结果显示，囊肿内衬为非角化的鳞状上皮，部分内衬为纤毛假层状柱状上皮，最终诊断为手术纤毛囊肿。总之，手术纤毛囊肿的发生应被视为上颌窦底提升术的延迟并发症，尽管其发生极为罕见。为了防止这种囊性病变的发展，在上颌窦底增强术中，必须小心地从骨表面剥离上颌窦膜，以尽量减少其损伤并避免其穿孔。

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引用次数: 0

Pleural disseminated cells mimicking malignant mesothelioma or adenocarcinoma metastasized from tongue squamous cell carcinoma: A case report and literature review 舌鳞癌转移的胸膜播散性细胞模拟恶性间皮瘤或腺癌：1例报告及文献复习

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Oral and Maxillofacial Surgery Medicine and Pathology

Pub Date : 2025-04-08 DOI: 10.1016/j.ajoms.2025.04.004

Kinuko Ogata , Shuichi Fujita , Rena Shido , Shun Narahara , Naoki Katase , Hirofumi Koike , Misa Sumi , Seigo Ohba , Tomohiro Yamada

It is well known that malignant tumors often dedifferentiate along with invasion and metastasis. Marked dedifferentiation in the distal metastasis makes it difficult to determine whether the metastatic tumor is from known primary origin, from another unknown primary origin, or it is not metastasis but independent primary tumor. Here we present a case of tongue squamous cell carcinoma (SCC) accompanied by pulmonary lymphangitic carcinomatosis (PLC) and carcinomatous pleuritis (CP) showing marked dedifferentiation. A 65-year-old man visited our hospital with complaint of lingual pain. The ulcered induration was histologically diagnosed as well differentiated SCC. After the tumor resection and neck dissection, symptoms and imaging test suggested PLC and CP. Cell block specimens of the pleural effusion exhibited atypical round cells mimic malignant mesothelioma or signet ring cell carcinoma within numerous poorly differentiated cells and undifferentiated cells. Histological diagnosis of these atypical cells was challenging. Immunohistochemical examination according to World Health Organization (WHO) classification of tumors of the lung and pleura revealed that they were positive for AE1/AE3, CK5/6, D2–40 and negative for calretinin, WT1, MOC31, CEA, BerEP4. These findings indicated that pleural disseminated cells were derived from tongue SCC. The pleural disseminated cells in this case were difficult to determine the cell origin due to marked dedifferentiation. It would be impossible to make correct diagnosis without information of clinical course and immunohistochemical examination. We have to keep in mind that there is unexpected dedifferentiated change associating with tumor metastasis.

众所周知，恶性肿瘤常伴随侵袭和转移而去分化。远端转移灶的明显去分化使得很难确定转移灶是来自已知原发灶，还是来自另一个未知原发灶，或者不是转移灶而是独立的原发灶。我们报告一例舌鳞状细胞癌（SCC）合并肺淋巴管癌（PLC）和癌性胸膜炎（CP），表现出明显的去分化。一名65岁男子来我院就诊，主诉舌痛。组织学诊断为分化良好的鳞状细胞癌。肿瘤切除和颈部清扫后，症状和影像学检查提示PLC和CP。胸腔积液细胞块标本显示非典型圆形细胞，类似恶性间皮瘤或印戒细胞癌，内有大量低分化细胞和未分化细胞。这些非典型细胞的组织学诊断具有挑战性。肺、胸膜肿瘤按WHO分级免疫组化检查，AE1/AE3、CK5/6、D2-40阳性，calretinin、WT1、MOC31、CEA、BerEP4阴性。这些结果表明胸膜播散性细胞来源于舌鳞癌。本例胸膜弥散性细胞由于去分化明显，难以确定细胞来源。如果没有临床病程和免疫组化检查，无法做出正确的诊断。我们必须记住，有意想不到的去分化变化与肿瘤转移有关。

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引用次数: 0

A salvage surgery case of mandibular reconstruction with serratus anterior muscle flap with pedicled rib graft having good clinical course in long-term observation 经长期观察，前锯肌瓣带蒂肋移植修复下颌重建术临床效果良好

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Oral and Maxillofacial Surgery Medicine and Pathology

Pub Date : 2025-03-28 DOI: 10.1016/j.ajoms.2025.03.011

Kengo Hashimoto , Kenichiro Ishibashi , Shigeyuki Fujiwara , Mizuki Hyodo , Yohei Ito , Masahiro Umemura

One-stage reconstruction after segmental mandibular resection typically involves using a vascularized bone graft due to the widespread development of free-tissue transfer techniques. The choice of reconstruction method is influenced by the length and location of the mandibular defect and the patient’s age, underlying conditions, and overall physical state. Currently, fibular or iliac bone flaps are often chosen because they can allow for a sufficient length of bone to be harvested and ensure the reproducibility of the natural mandible shape. Conversely, scapular and rib flaps, which require patient repositioning, are less preferred because of existing concerns regarding their strength and consistency with the mandible’s shape. In addition, mandibular reconstruction using a reconstruction plate can result in postoperative complications such as plate infection and fracture, in some patients. These complications often require plate removal and additional reconstructive surgery. Herein, we present the case of a 73-year-old man who underwent segmental mandibulectomy and plate reconstruction for a right mandibular gingival malignancy. Fifty-four months later, a fracture of the reconstructed plate was observed. We report the treatment experience of performing rib flap re-reconstruction as a salvage procedure for a fractured reconstruction plate. Although this approach was necessitated by the difficulty of using the healthy lower limb under the absence of the right lower limb, resulting in a stable long-term outcome.

由于自由组织移植技术的广泛发展，下颌骨节段性切除后一期重建通常涉及血管化骨移植物。重建方法的选择受下颌缺损的长度和位置以及患者的年龄、基础条件和整体身体状况的影响。目前，通常选择腓骨或髂骨皮瓣，因为它们可以获得足够长的骨，并确保自然下颌骨形状的再现性。相反，由于担心其强度和与下颌骨形状的一致性，需要患者重新定位的肩胛骨和肋骨瓣不太受欢迎。此外，在一些患者中，使用重建钢板进行下颌骨重建会导致钢板感染和骨折等术后并发症。这些并发症通常需要钢板取出和额外的重建手术。在此，我们提出的情况下，一个73岁的男子谁接受了节段性下颌骨切除术和钢板重建右下颌骨牙龈恶性肿瘤。54个月后，观察到重建钢板骨折。我们报告肋骨瓣重建作为修复骨折重建钢板的治疗经验。虽然由于右下肢缺失时难以使用健康的下肢，这种方法是必要的，但结果是长期稳定的。

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引用次数: 0

Extraction in a patient with Type 3 von Willebrand disease: A case of effective hemostasis after administration of Vonicog Alfa 3型血管性血友病患者的拔除术：Vonicog Alfa有效止血1例

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Oral and Maxillofacial Surgery Medicine and Pathology

Pub Date : 2025-03-26 DOI: 10.1016/j.ajoms.2025.03.010

Taifu Hirano , Tadashi Kawai , Kotaro Shibata , Isao Hoshi , Toshimi Chiba , Hiroyuki Yamada

Tooth extraction in patients with von Willebrand disease (VWD) is difficult because of the associated bleeding. Current treatment involves the use of plasma-derived von Willebrand factor (VWF), and recombinant VWF has recently been developed. This report describes a case of tooth extraction in which hemostasis was successfully achieved with the use of recombinant VWF. The patient was an older male who presented to our department for a tooth extraction. His medical history included uncontrolled bleeding after sinus surgery and factor VIII deficiency. After investigation, a diagnosis of type 3 VWD was made. On the day of admission, recombinant VWF was administered, and the mandibular left first molar was extracted under local anesthesia the next day. The patient was treated with recombinant VWF until the fifth day. The patient had no postoperative bleeding. This outcome suggests that recombinant VWF is effective for tooth extraction in VWD patients.

血管性血友病（VWD）患者的拔牙是困难的，因为相关的出血。目前的治疗包括使用血浆源性血管性血友病因子（VWF），重组VWF最近得到了发展。本报告描述了一例拔牙，其中使用重组VWF成功止血。患者是一名老年男性，他来我科拔牙。他的病史包括鼻窦手术后无法控制的出血和因子VIII缺乏。经调查，诊断为3型VWD。入院当天给予重组VWF，次日局部麻醉下拔除下颌左第一磨牙。重组VWF治疗至第5天。患者术后无出血。这一结果表明重组VWF对VWD患者的拔牙是有效的。

引用次数: 0

Osteosarcoma of the jaw in an adult patient aged more than 40 years successfully treated with neoadjuvant chemotherapy comprising doxorubicin and ifosfamide: A case report 年龄超过40岁的成人颌骨骨肉瘤患者成功地接受了由阿霉素和异环磷酰胺组成的新辅助化疗：1例报告

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Oral and Maxillofacial Surgery Medicine and Pathology

Pub Date : 2025-03-26 DOI: 10.1016/j.ajoms.2025.03.008

Yusuke Tsuda , Masanobu Abe , Kenichi Kumagai , Toshihiro Kikuta , Kazuto Hoshi

Although the mandible is the fourth most common site for osteosarcoma, the standard treatment for these patients remains unclear. A 59-year-old woman presented with mandibular pain. Imaging studies revealed a bone-forming mass with extraosseous extension in the mandible. Biopsy results revealed spindle-to-stellate tumour cells with irregular nuclei and osteoid formation, indicating high-grade osteosarcoma. After preoperative chemotherapy with doxorubicin and ifosfamide, osteosarcoma of the jaw was resected with adequate margins. Histological analysis revealed > 90 % tumour necrosis. Patients achieving a tumour necrosis rate of > 90 % after preoperative chemotherapy have shown significantly better prognoses than those with a necrosis rate of < 90 % in osteosarcoma of the extremities and trunk. Although no consensus has been reached on the effectiveness of preoperative chemotherapy for osteosarcoma of the jaw or osteosarcoma in patients aged > 40 years, neoadjuvant chemotherapy with doxorubicin and ifosfamide may achieve favorable oncological outcomes in selected patients aged > 40 years with high-grade osteosarcoma of the jaw.

虽然下颌骨是骨肉瘤的第四大常见部位，但对这些患者的标准治疗仍不清楚。一名59岁女性，以下颌骨疼痛为主诉。影像学检查显示下颌骨有骨外延伸的骨形成肿块。活检结果显示梭形到星形的肿瘤细胞，细胞核不规则，骨样形成，提示高级别骨肉瘤。术前用阿霉素和异环磷酰胺化疗后，切除颌骨骨肉瘤，留下足够的切缘。组织学分析显示>； 90 %肿瘤坏死。术前化疗后肿瘤坏死率为 90 %的患者预后明显优于四肢和躯干骨肉瘤坏死率为 90 %的患者。虽然对于年龄>； 40岁的颌骨骨肉瘤或骨肉瘤患者术前化疗的有效性尚未达成共识，但对于年龄>； 40岁的颌骨高级别骨肉瘤患者，阿霉素和异环磷酰胺的新辅助化疗可能会取得良好的肿瘤学结果。

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引用次数: 0

Efficacy of nano-emulsion quercetin gel post third molar extraction 槲皮素纳米乳凝胶第三摩尔萃取后的药效研究

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Oral and Maxillofacial Surgery Medicine and Pathology

Pub Date : 2025-03-26 DOI: 10.1016/j.ajoms.2025.03.009

Rashi S. Jain , Pushkar P. Waknis , Samkit V. Sakhariya , Tanvi N. Tiwarekar

AIM

Wound healing encompasses a multifaceted sequence of events, comprising inflammation, blood coagulation, fibroplasia, and collagen deposition. However, following third molar surgeries, patients frequently contend with pain, inflammation, and swelling, presenting significant obstacles to the natural progression of wound healing. Quercetin, a natural flavanol renowned for its myriad health benefits, exhibits potent anti-inflammatory, anti-cancer, anti-viral, and antioxidant properties. Leveraging these attributes, we propose the development and assessment of a Nano Emulsion Quercetin gel for wound healing post 3rd molar surgery. The envisioned Nano Emulsion Quercetin gel holds promise as an innovative, targeted intervention to improve postoperative recovery and outcomes.

Material and methods

The trial cohort was prospectively allocated for treatment of surgical removal of mandibular third molar throughout a 12-month period. Participants were randomly assigned to either with nano-emulsion gel or without nano-emulsion gel groups. Nano-emulsion Quercetin gel was formulated and placed in the socket after 3rd molar removal. Post-operative Edema, pain and soft tissue healing was assessed on day 1, day 3 and day 7. Bone assessment was carried out post operative 1st week, 4th week, and 8th week to observe the bone re-fill in the socket.

Result

The study included total 36 patients (18 Female and 18 male). Group with Nano-Emulsion quercetin gel had a statistically significant influence on reducing post-operative pain and edema. Wound healing with bone formation with Nano-emulsion quercetin gel was significantly better.

Conclusion

This study provides valuable insights into the efficacy of nano-emulsion quercetin gel in reducing post-operative pain, swelling, and promoting superior wound healing following third molar surgery.

伤口愈合包括多方面的事件序列，包括炎症、血液凝固、纤维增生和胶原沉积。然而，在第三磨牙手术后，患者经常会出现疼痛、炎症和肿胀，这对伤口的自然愈合造成了很大的障碍。槲皮素是一种天然黄烷醇，以其多种健康益处而闻名，具有有效的抗炎、抗癌、抗病毒和抗氧化特性。利用这些特性，我们提出了一种纳米乳槲皮素凝胶用于第三磨牙手术后伤口愈合的开发和评估。设想的纳米乳槲皮素凝胶有望作为一种创新的，有针对性的干预措施，以改善术后恢复和结果。材料和方法试验队列被前瞻性地分配为手术切除下颌第三磨牙的治疗，为期12个月。参与者被随机分配到使用纳米乳液凝胶组或不使用纳米乳液凝胶组。制备纳米乳槲皮素凝胶，去除第三磨牙后置于牙槽内。术后第1天、第3天、第7天分别评估水肿、疼痛和软组织愈合情况。术后第1周、第4周、第8周进行骨评估，观察窝内骨再填充情况。结果共纳入36例患者，其中女18例，男18例。纳米乳槲皮素凝胶组对减轻术后疼痛和水肿有统计学意义。槲皮素纳米乳凝胶对成骨创面愈合效果显著。结论纳米乳槲皮素凝胶在减少第三磨牙术后疼痛、肿胀和促进创面愈合方面的作用。

{"title":"Efficacy of nano-emulsion quercetin gel post third molar extraction","authors":"Rashi S. Jain , Pushkar P. Waknis , Samkit V. Sakhariya , Tanvi N. Tiwarekar","doi":"10.1016/j.ajoms.2025.03.009","DOIUrl":"10.1016/j.ajoms.2025.03.009","url":null,"abstract":"<div><h3>AIM</h3><div>Wound healing encompasses a multifaceted sequence of events, comprising inflammation, blood coagulation, fibroplasia, and collagen deposition. However, following third molar surgeries, patients frequently contend with pain, inflammation, and swelling, presenting significant obstacles to the natural progression of wound healing. Quercetin, a natural flavanol renowned for its myriad health benefits, exhibits potent anti-inflammatory, anti-cancer, anti-viral, and antioxidant properties. Leveraging these attributes, we propose the development and assessment of a Nano Emulsion Quercetin gel for wound healing post 3rd molar surgery. The envisioned Nano Emulsion Quercetin gel holds promise as an innovative, targeted intervention to improve postoperative recovery and outcomes.</div></div><div><h3>Material and methods</h3><div>The trial cohort was prospectively allocated for treatment of surgical removal of mandibular third molar throughout a 12-month period. Participants were randomly assigned to either with nano-emulsion gel or without nano-emulsion gel groups. Nano-emulsion Quercetin gel was formulated and placed in the socket after 3rd molar removal. Post-operative Edema, pain and soft tissue healing was assessed on day 1, day 3 and day 7. Bone assessment was carried out post operative 1st week, 4th week, and 8th week to observe the bone re-fill in the socket.</div></div><div><h3>Result</h3><div>The study included total 36 patients (18 Female and 18 male). Group with Nano-Emulsion quercetin gel had a statistically significant influence on reducing post-operative pain and edema. Wound healing with bone formation with Nano-emulsion quercetin gel was significantly better.</div></div><div><h3>Conclusion</h3><div>This study provides valuable insights into the efficacy of nano-emulsion quercetin gel in reducing post-operative pain, swelling, and promoting superior wound healing following third molar surgery.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 5","pages":"Pages 1044-1050"},"PeriodicalIF":0.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Submandibular gland mucocele caused by submental liposuction 颏下吸脂引起的颌下腺粘液囊肿

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Oral and Maxillofacial Surgery Medicine and Pathology

Pub Date : 2025-03-20 DOI: 10.1016/j.ajoms.2025.03.007

Taiga Kaneko, Toshinori Iwai, Satomi Sugiyama, Senri Oguri, Kenji Mitsudo

Submental liposuction is performed for patients with submental fullness and is one of the most common cosmetic surgical procedures. Although severe complications associated with submental liposuction are rare, there are no reports of iatrogenic submandibular gland (SMG) mucocele. We report a rare case of SMG mucocele caused by submental liposuction. A 25-year-old man was referred to our department for left submandibular swelling. Three years before the first visit, the patient visited another hospital for left submandibular swelling. Magnetic resonance imaging showed a cystic lesion in the left submandibular region, and the patient was diagnosed with a plunging ranula. The patient underwent sublingual gland removal, and the postoperative course was uneventful. Three months before the first visit, the patient underwent submental liposuction at a private cosmetic surgery clinic. Computed tomography revealed a well-circumscribed, submandibular cystic lesion arising from the anterior portion of the SMG. Fine needle aspiration showed yellow mucus. Because the clinical and radiological diagnosis was SMG mucocele, the patient underwent SMG removal in a submandibular approach. The postoperative course was uneventful, and there was no recurrence 5 months after the surgery.

颏下吸脂术用于颏下丰满的患者，是最常见的美容外科手术之一。虽然与颏下吸脂术相关的严重并发症是罕见的，但没有医源性颌下腺（SMG）粘液囊肿的报道。我们报告一例由颏下吸脂引起的SMG黏液囊肿。一名25岁男子因左下颌下肿大转介至我科。首次就诊前3年，患者因左侧下颌下肿大到另一家医院就诊。磁共振成像显示左侧下颌下区域囊性病变，患者被诊断为下陷。患者接受了舌下腺切除术，术后过程顺利。在第一次就诊前三个月，患者在一家私人整容诊所接受了颏下吸脂手术。计算机断层扫描显示一边界清晰的下颌下囊性病变，起源于SMG前部。细针抽吸显示黄色粘液。由于临床和放射学诊断为SMG粘液囊肿，患者在下颌下入路行SMG切除。术后过程平稳，术后5个月无复发。

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引用次数: 0

Malignant transformation of ameloblastoma: A case report and literature review 成釉细胞瘤恶性转化1例并文献复习

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Oral and Maxillofacial Surgery Medicine and Pathology

Pub Date : 2025-03-15 DOI: 10.1016/j.ajoms.2025.03.003

Jiayi Wang , Baican Wang , Jiahui Dai , Yanli Wang , Ling Bi , Yangxi Cheng , Xirui Wang , Huiyong Zhu

Ameloblastic carcinoma is an odontogenic malignancy that is divided into a primary type called de novo cancer and a secondary type, a malignant transformation of an existing benign ameloblastoma. Most reported cases of ameloblastic carcinoma occur de novo, while few are caused by malignant degeneration of benign ameloblastoma. This study reports a case of mandibular secondary type ameloblastic carcinoma with malignant transformation 2 months after primary surgery. The patient received extended resection and postoperative radiotherapy. Eight months after operation, the skin flap had good color and soft texture, and the mandibular movement function and facial shape recovered well. We also reviewed 32 cases of secondary type ameloblastic carcinoma and analyzed the clinical features, treatment and results, suggesting that clinicians should pay attention to the possibility of malignant transformation of ameloblastoma and provide guidance for its treatment.

成釉细胞癌是一种牙源性恶性肿瘤，分为原发型（新生癌）和继发型（良性成釉细胞瘤的恶性转化）。大多数报告的成釉细胞癌是新生的，而少数是由良性成釉细胞瘤的恶性变性引起的。本研究报告一例下颌骨继发性成釉细胞癌在初次手术后2个月发生恶性转化。患者接受了扩大切除和术后放疗。术后8个月皮瓣颜色好，质地柔软，下颌骨运动功能和颜面形态恢复良好。我们还回顾了32例继发性成釉细胞癌的临床特点、治疗方法和结果，提示临床医生应重视成釉细胞瘤恶性转化的可能性，并对其治疗提供指导。

引用次数: 0

Changes in the structure and function of tongue before and after orthognathic surgery: Retrospective study 正颌手术前后舌结构和功能的变化：回顾性研究

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Oral and Maxillofacial Surgery Medicine and Pathology

Pub Date : 2025-03-13 DOI: 10.1016/j.ajoms.2025.03.006

Riku Kohara , Karen Gomi , Atsuya Ishiyama , Sumire Ono , Young Min Shin , Akinori Moroi , Kunio Yoshizawa , Koichiro Ueki

Objective

This study aimed to compare changes in tongue morphology and function before and after orthognathic surgery.

Methods

Sixty patients with jaw deformities who underwent orthognathic surgery were enrolled. Tongue pressure, computed tomography (CT), and cephalometric analyses were performed before and one-year post-surgery. Tongue pressure was measured using a pressure-measuring device (TPM-02®; JMS Co., Ltd, Tokyo, Japan). Participants were instructed to press their tongues with maximum force for 20 s, and measurements were repeated three times, with the mean value used for analysis. CT images were reconstructed using ProPlan CMF (Materialize, Belgium), and CT values of the tongue were measured. Cephalograms were analyzed using Cephalometric A to Z software (Yasunaga Labo Com, Fukui, Japan), with key measurements being tongue length (TGL), tongue height (TGH), and tongue area.

Results

In class II females, postoperative tongue pressure, tongue area, length, height, and CT values were significantly higher than pre-operative values. Before surgery, class II females exhibited significantly lower tongue pressure, tongue area, and tongue length than other groups, although this was not observed one year after the operation.

Conclusions

This study suggests that orthognathic surgery significantly alters tongue morphology and function, affecting CT values.

目的比较正颌手术前后舌形态和功能的变化。方法选取60例行正颌手术的颌骨畸形患者。术前和术后1年分别进行舌压、计算机断层扫描（CT）和头颅测量分析。使用压力测量装置（TPM-02®）测量舌压；JMS株式会社，日本东京)。参与者被要求以最大的力量按压他们的舌头20 s，测量重复三次，平均值用于分析。使用ProPlan CMF （Materialize, Belgium）软件重建CT图像，测量舌部CT值。使用Cephalometric A to Z软件（Yasunaga Labo Com, Fukui, Japan）分析脑图，主要测量舌长（TGL）、舌高（TGH）和舌面积。结果II类女性术后舌压、舌面积、舌长、舌高及CT值均显著高于术前。手术前，II类女性的舌压、舌面积和舌长明显低于其他组，尽管在手术一年后没有观察到这种情况。结论正颌手术可显著改变舌部形态和功能，影响CT值。

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引用次数: 0

Platelet rich fibrin versus hydroxyapatite in the management of periapical inflammatory lesions: A prospective clinico-radiographic comparative analysis 富血小板纤维蛋白与羟基磷灰石治疗根尖周围炎性病变：前瞻性临床放射学比较分析

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Oral and Maxillofacial Surgery Medicine and Pathology

Pub Date : 2025-03-10 DOI: 10.1016/j.ajoms.2025.03.005

Swasti Bhardwaj, Gaurav Singh, Amit Gaur

Objective

This study evaluates and compares clinical and radiographic outcomes following periapical surgery using Platelet Rich Fibrin (PRF) or Hydroxyapatite (HA) bone graft as filling materials for periapical defects.

Method

Sixty patients with periapical pathology in the maxillary anterior region (1–2 cm) were included. They were randomly divided into three groups of 20 patients each. The entire periapical lesion was removed and manual curettage was done. After completion of periapical surgery (Apicoectomy); Group I(control) had the defect left unfilled, Group II received HA bone graft, and Group III received PRF. Clinical and radiographic parameters were assessed at various intervals.

Result

No statistically significant difference in post-operative pain was found among the groups, though Group III experienced the least pain. Swelling was present initially in all groups but resolved faster in Group III. Tooth mobility was least in Group III at the 1st and 3rd months, with no mobility in Groups II and III by the 6th month. Group III exhibited the best soft tissue healing. Mean bone density was highest in Group III at 1st, 6th, and 9th months, with a statistically significant result in group III(P = .033) and in intragroup comparison between Groups I and III at 9 months (P = .043).

Conclusion

PRF emerged as the preferred graft material due to its autologous nature, cost-effectiveness and ability to promote healing through the release of growth factors. However, the choice between PRF and hydroxyapatite should be guided by specific clinical requirements and desired outcomes.

目的评价和比较富血小板纤维蛋白（PRF）或羟基磷灰石（HA）骨移植作为根尖周缺损填充材料后的临床和影像学结果。方法选取上颌前区（1 ~ 2 cm）根尖周病变患者60例。他们被随机分为三组，每组20名患者。切除整个根尖周病变，手工刮除。完成根尖周围手术（根尖切除术）后；ⅰ组（对照组）缺损不补，ⅱ组采用HA骨移植，ⅲ组采用PRF。在不同的时间间隔评估临床和放射学参数。结果两组患者术后疼痛程度差异无统计学意义，第三组患者术后疼痛程度最低。所有组最初均出现肿胀，但第三组消退更快。第1个月和第3个月时，第三组的牙齿活动最少，第6个月时，第二组和第三组的牙齿没有活动。第三组软组织愈合效果最好。第1、6、9个月时，III组平均骨密度最高，差异有统计学意义（P = .033）；第9个月时，I组与III组间比较差异有统计学意义（P = .043）。结论prf因其自身的特性、成本效益和通过释放生长因子促进愈合的能力而成为首选的移植材料。然而，在PRF和羟基磷灰石之间的选择应以具体的临床要求和期望的结果为指导。

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引用次数: 0