Pub Date : 2024-03-24DOI: 10.1016/j.ajoms.2024.03.007
The mandibular canal rarely penetrates the apically fused tooth roots. In this report, we describe three cases of patients in whom the mandibular canal ran between the roots of embedded mandibular teeth with apical fusion. Case 1: A 43-year-old man presented with a completely embedded left mandibular first molar and a swollen gingiva. Cone beam computed tomography revealed apical root fusion and a mandibular canal penetrating the root. Case 2: Cone-beam computed tomography of a 39-year-old female revealed root apical fusion and a mandibular canal between the roots. Case 3: Cone-beam computed tomography of a 30-year-old female with a fully erupted left mandibular third molar revealed a ring of diverging roots fused to the root apex. The mandibular canal runs between the mandibular roots. All three patients were treated under general anesthesia and developed postoperative inferior alveolar nerve palsy; however, their sensory function recovered over time. The prognosis was good in all patients, none of whom experienced any other complications.
{"title":"Three cases of mandibular molars with roots surrounding the inferior alveolar neurovascular bundle","authors":"","doi":"10.1016/j.ajoms.2024.03.007","DOIUrl":"10.1016/j.ajoms.2024.03.007","url":null,"abstract":"<div><p><span>The mandibular canal rarely penetrates the apically fused tooth roots. In this report, we describe three cases of patients in whom the mandibular canal ran between the roots of embedded mandibular teeth with apical fusion. Case 1: A 43-year-old man presented with a completely embedded left </span>mandibular first molar<span><span> and a swollen gingiva<span>. Cone beam computed tomography revealed apical root fusion and a mandibular canal penetrating the root. Case 2: Cone-beam computed tomography of a 39-year-old female revealed root apical fusion and a mandibular canal between the roots. Case 3: Cone-beam computed tomography of a 30-year-old female with a fully erupted left </span></span>mandibular third molar<span><span> revealed a ring of diverging roots fused to the root apex. The mandibular canal runs between the mandibular roots. All three patients were treated under general anesthesia and developed postoperative </span>inferior alveolar nerve palsy; however, their sensory function recovered over time. The prognosis was good in all patients, none of whom experienced any other complications.</span></span></p></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140401277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-19DOI: 10.1016/j.ajoms.2024.03.006
Objectives
The present work aimed to examine the early and late histopathological changes occurring in the lower lips of rats, as a result of hyaluronic acid injection, and to determine whether it could really bring us closer to the ideal soft tissue filler material. This research highlights the importance of experimental studies on this subject, since adverse reactions have been observed routinely in dental practice.
Material and methods
The present study was carried out on 36 adult male albino rats and was divided into two equal groups, each consisting of 18 rats; group I (control group) and group II (experimental group). Rats in the experimental group were injected with hyaluronic acid (0.07 ml), whereas rats in the control group were injected with 0.9% sodium chloride.
Results
The results showed inflammation triggered by the injection of hyaluronic acid. On examining the specimens histologically using Hematoxylin and Eosin stains, Toluidine Blue stain and immunohistochemistry with anti-CD68 antibody, there was a significantly greater inflammatory response in the groups at early interval with hyaluronic acid compared with the control (P < 0.0001). Higher collagen formation was also observed with Masson’s Trichrome staining.
Conclusion
The undesirable effects of hyaluronic acid filler injection can be detected at early intervals following its injection. Fortunately, all the undesirable effects are transient and decrease by time, reaching levels comparable to normal. Overall, HA was well-tolerated by tissues, reflecting how this filler material possesses a biocompatible property.
{"title":"Evaluation of the histopathological effects of injectable hyaluronic acid as a filler material in rat’s lip","authors":"","doi":"10.1016/j.ajoms.2024.03.006","DOIUrl":"10.1016/j.ajoms.2024.03.006","url":null,"abstract":"<div><h3>Objectives</h3><p>The present work aimed to examine the early and late histopathological changes occurring in the lower lips of rats, as a result of hyaluronic acid<span> injection, and to determine whether it could really bring us closer to the ideal soft tissue filler material. This research highlights the importance of experimental studies on this subject, since adverse reactions have been observed routinely in dental practice.</span></p></div><div><h3>Material and methods</h3><p>The present study was carried out on 36 adult male albino rats<span> and was divided into two equal groups, each consisting of 18 rats; group I (control group) and group II (experimental group). Rats in the experimental group were injected with hyaluronic acid (0.07 ml), whereas rats in the control group were injected with 0.9% sodium chloride.</span></p></div><div><h3>Results</h3><p><span><span>The results showed inflammation triggered by the injection of hyaluronic acid. On examining the specimens histologically using Hematoxylin and </span>Eosin stains, </span>Toluidine Blue<span><span> stain and immunohistochemistry with anti-CD68 antibody, there was a significantly greater inflammatory response in the groups at early interval with hyaluronic acid compared with the control (P < 0.0001). Higher collagen formation was also observed with Masson’s </span>Trichrome staining.</span></p></div><div><h3>Conclusion</h3><p>The undesirable effects of hyaluronic acid filler injection can be detected at early intervals following its injection. Fortunately, all the undesirable effects are transient and decrease by time, reaching levels comparable to normal. Overall, HA was well-tolerated by tissues, reflecting how this filler material possesses a biocompatible property.</p></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140276932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-12DOI: 10.1016/j.ajoms.2024.03.005
Hereditary angioedema (HAE) with normal C1 inhibitor (C1-INH) (HAE-nC1-INH) is a rare disease that presents with laryngeal edema due to oral surgical procedures. Familial Mediterranean fever (FMF) is a disorder commonly characterized by an autosomal recessive inflammatory process, and manifests in the oral cavity and facial structures. A 50-year-old woman with HAE-nC1-INH and FMF was referred to our department for bone augmentation in the right maxillary molar region. We performed lateral window sinus augmentation under the backup support of an anesthesiologist. A hematologist used intravenous Berinert® and oral Orladeyo® to prevent perioperative angioedema attacks. The postoperative course was uneventful. Regarding surgical intervention in patients with HAE, interdepartmental cooperation is crucial to prevent angioedema attacks and prepare for life-threatening complications. Oral hygiene and occlusion should be considered in the dental implant treatment of patients with FMF. Every oral and maxillofacial surgeon and dental practitioner should familiarize themselves with HAE and FMF.
{"title":"Maxillary sinus augmentation in a patient with hereditary angioedema with normal C1 inhibitor and familial Mediterranean fever","authors":"","doi":"10.1016/j.ajoms.2024.03.005","DOIUrl":"10.1016/j.ajoms.2024.03.005","url":null,"abstract":"<div><p><span><span><span><span>Hereditary angioedema<span> (HAE) with normal C1 inhibitor<span> (C1-INH) (HAE-nC1-INH) is a rare disease that presents with laryngeal edema due to oral surgical procedures. </span></span></span>Familial Mediterranean fever (FMF) is a disorder commonly characterized by an </span>autosomal recessive inflammatory process, and manifests in the </span>oral cavity<span> and facial structures. A 50-year-old woman with HAE-nC1-INH and FMF was referred to our department for bone augmentation in the right maxillary molar region. We performed lateral window sinus augmentation under the backup support of an anesthesiologist. A hematologist used intravenous Berinert® and oral Orladeyo® to prevent perioperative angioedema attacks. The postoperative course was uneventful. Regarding surgical intervention in patients with HAE, interdepartmental cooperation is crucial to prevent angioedema attacks and prepare for life-threatening complications. </span></span>Oral hygiene<span> and occlusion should be considered in the dental implant<span> treatment of patients with FMF. Every oral and maxillofacial surgeon and dental practitioner should familiarize themselves with HAE and FMF.</span></span></p></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140282767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-12DOI: 10.1016/j.ajoms.2024.03.004
Objective
Predicting postoperative airway obstruction during oral cancer surgery is difficult. We aimed to investigate the relationship between postoperative airway obstruction and surgery in patients.
Methods
Patients (n = 100, men: 72, women: 28) with oral malignancies who underwent surgery between January 2020 and December 2022 were included. The outcome was postoperative airway obstruction. Age, sex, alcohol, smoking history, BMI, tumor site, T and N classification, stage, surgical method, lymphatic invasion, vascular invasion, perineural invasion, DOI, airway management, occurrence and duration of postoperative airway obstruction were investigated. We defined airway obstruction as confirmed symptoms such as dyspnoea and wheezing, drop in SpO2 below 90 %, stridor auscultation and pharyngeal stenosis by endoscope.
The relationship between airway obstruction and patient characteristics was analyzed using Fisher's exact test. The Kaplan–Meier method was used to assess onset of airway obstruction, and the time to onset of airway obstruction was compared using the log-rank test. Airway obstruction and surgery-related factors were evaluated using Cox regression models.
Results
Airway obstruction occurred in 6 patients within 12 h. Multivariate analysis revealed that age > 65 years, lymphatic invasion and DOI (cut-off value: 7.00 mm) were independent risk factors for occurrence of airway obstruction.
Conclusion
Local resection of tumors ≥ 7 mm in DOI is associated with airway obstruction owing to factors such as swelling associated with deep resection. Age, lymphatic invasion are also associated with airway obstruction, requiring ward management according to the protocols of each institution with attention to postoperative hematoma and edema that may cause airway obstruction.
{"title":"Association between oral cancer surgery and postoperative airway obstruction: A retrospective study","authors":"","doi":"10.1016/j.ajoms.2024.03.004","DOIUrl":"10.1016/j.ajoms.2024.03.004","url":null,"abstract":"<div><h3>Objective</h3><p>Predicting postoperative airway obstruction during oral cancer surgery is difficult. We aimed to investigate the relationship between postoperative airway obstruction and surgery in patients.</p></div><div><h3>Methods</h3><p>Patients (n = 100, men: 72, women: 28) with oral malignancies who underwent surgery between January 2020 and December 2022 were included. The outcome was postoperative airway obstruction. Age, sex, alcohol, smoking history, BMI, tumor site, T and N classification, stage, surgical method, lymphatic invasion, vascular invasion, perineural invasion, DOI, airway management, occurrence and duration of postoperative airway obstruction were investigated. We defined airway obstruction as confirmed symptoms such as dyspnoea and wheezing, drop in SpO2 below 90 %, stridor auscultation and pharyngeal stenosis by endoscope.</p><p>The relationship between airway obstruction and patient characteristics was analyzed using Fisher's exact test. The Kaplan–Meier method was used to assess onset of airway obstruction, and the time to onset of airway obstruction was compared using the log-rank test. Airway obstruction and surgery-related factors were evaluated using Cox regression models.</p></div><div><h3>Results</h3><p>Airway obstruction occurred in 6 patients within 12 h. Multivariate analysis revealed that age > 65 years, lymphatic invasion and DOI (cut-off value: 7.00 mm) were independent risk factors for occurrence of airway obstruction.</p></div><div><h3>Conclusion</h3><p>Local resection of tumors ≥ 7 mm in DOI is associated with airway obstruction owing to factors such as swelling associated with deep resection. Age, lymphatic invasion are also associated with airway obstruction, requiring ward management according to the protocols of each institution with attention to postoperative hematoma and edema that may cause airway obstruction.</p></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212555824000498/pdfft?md5=f8c4b1990938c4310618796ccdf8541d&pid=1-s2.0-S2212555824000498-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140276584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-06DOI: 10.1016/j.ajoms.2024.03.003
Objective
This study aimed to study on the MRI findings suggesting intra-articular pathologies in patients with temporomandibular disorders (TMD) undergone successful non-surgical treatments, and to discuss on their intra-articular pathological conditions with clinical symptoms.
Patients and methods
One-hundred eleven TMJs of the consecutive 80 TMD patients were enrolled in this study. These TMJs were classified into the following 3 Groups, Group I: Bilateral 62 TMJs of the 31 patients with masticatory-muscle (MM) symptoms without functional pain, Group II: Affected-side TMJs of the 31 patients with unilateral functional MM pain, Group III: Affected-side TMJs of the 18 patients with unilateral functional TMJ pain. The detection rates of joint effusion (JE), osteoarthritis (OA), and disc displacement (DD) on the MR images were investigated. The correlations of JE, OA, DD, age, and gender were also analyzed.
Results
In each Group, the detection rates of JE, OA, and DD were more than 70%, and no findings of them were sometimes observed. The detection ratio of moderate/marked JE in Group II was significantly higher among the 3 Groups. The significant correlation of JE, OA, and DD was found, and that of OA and age was also observed.
Conclusions
Our results suggest that intra-articular pathologies often occur even in the painless TMJs, and functional TMJ pain sometimes appear even in the TMJs with early-stage OA, which cannot be detected by MRI. Furthermore, the TMJ synovitis occurred in patients with functional MM pain may be more severe than that in the painful TMJ.
本研究旨在对成功接受非手术治疗的颞下颌关节紊乱症(TMD)患者关节内病变的磁共振成像结果进行研究,并结合临床症状对其关节内病变情况进行讨论。这些颞下颌关节被分为以下三组:第一组:31 名有咀嚼肌(MM)症状但无功能性疼痛的患者的双侧 62 个颞下颌关节;第二组:31 名有单侧功能性 MM 疼痛的患者的受累侧颞下颌关节;第三组:18 名有单侧功能性颞下颌关节疼痛的患者的受累侧颞下颌关节。研究了磁共振图像上关节积液(JE)、骨关节炎(OA)和椎间盘移位(DD)的检出率。结果 在各组中,JE、OA 和 DD 的检出率均超过 70%,有时甚至未发现。第二组中度/标记性 JE 的检出率在三组中明显较高。结论我们的研究结果表明,即使是无痛的颞下颌关节也经常出现关节内病变,即使是有早期颞下颌关节炎的颞下颌关节有时也会出现功能性颞下颌关节痛,而磁共振成像却无法检测到这些病变。此外,功能性颞下颌关节疼痛患者的颞下颌关节滑膜炎可能比疼痛型颞下颌关节滑膜炎更为严重。
{"title":"Intra-articular pathologies detected by magnetic resonance imaging in patients with temporomandibular disorders undergone successful non-surgical treatments","authors":"","doi":"10.1016/j.ajoms.2024.03.003","DOIUrl":"10.1016/j.ajoms.2024.03.003","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to study on the MRI findings suggesting intra-articular pathologies in patients with temporomandibular disorders (TMD) undergone successful non-surgical treatments, and to discuss on their intra-articular pathological conditions with clinical symptoms.</p></div><div><h3>Patients and methods</h3><p>One-hundred eleven TMJs of the consecutive 80 TMD patients were enrolled in this study. These TMJs were classified into the following 3 Groups, Group I: Bilateral 62 TMJs of the 31 patients with masticatory-muscle (MM) symptoms without functional pain, Group II: Affected-side TMJs of the 31 patients with unilateral functional MM pain, Group III: Affected-side TMJs of the 18 patients with unilateral functional TMJ pain. The detection rates of joint effusion (JE), osteoarthritis (OA), and disc displacement (DD) on the MR images were investigated. The correlations of JE, OA, DD, age, and gender were also analyzed.</p></div><div><h3>Results</h3><p>In each Group, the detection rates of JE, OA, and DD were more than 70%, and no findings of them were sometimes observed. The detection ratio of moderate/marked JE in Group II was significantly higher among the 3 Groups. The significant correlation of JE, OA, and DD was found, and that of OA and age was also observed.</p></div><div><h3>Conclusions</h3><p>Our results suggest that intra-articular pathologies often occur even in the painless TMJs, and functional TMJ pain sometimes appear even in the TMJs with early-stage OA, which cannot be detected by MRI. Furthermore, the TMJ synovitis occurred in patients with functional MM pain may be more severe than that in the painful TMJ.</p></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212555824000280/pdfft?md5=0ad042cc2afaf938bd24ce7782dab4ea&pid=1-s2.0-S2212555824000280-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140279390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-06DOI: 10.1016/j.ajoms.2024.03.001
Ameloblastic fibroma (AF) is a rare benign tumor, with approximately 80% of AF cases occurring in patients below the age of 22 years. Notably, it is less frequent (16.9%) in patients aged ≤ 10 years. Most cases of AF occur in the mandible, with only a few occurrences in the maxilla. Herein, we report a case of AF in the maxilla of an 8-year-old child. In the present case, AF was suggested to have impaired the development of permanent teeth. Regular checkups, including radiographic examinations starting in childhood, may facilitate early detection of lesions in the maxillofacial region.
坏细胞纤维瘤(AF)是一种罕见的良性肿瘤,约80%的AF病例发生在22岁以下的患者身上。值得注意的是,在年龄小于 10 岁的患者中,其发病率较低(16.9%)。大多数 AF 病例发生在下颌骨,只有少数发生在上颌骨。在此,我们报告了一例发生在一名 8 岁儿童上颌骨的房颤病例。在本病例中,房颤被认为影响了恒牙的发育。从儿童时期开始进行定期检查,包括放射线检查,有助于及早发现颌面部的病变。
{"title":"A case of ameloblastic fibroma in the maxilla of an 8-year-old child: A case report and literature review","authors":"","doi":"10.1016/j.ajoms.2024.03.001","DOIUrl":"10.1016/j.ajoms.2024.03.001","url":null,"abstract":"<div><p><span><span>Ameloblastic fibroma (AF) is a rare </span>benign tumor<span>, with approximately 80% of AF cases occurring in patients below the age of 22 years. Notably, it is less frequent (16.9%) in patients aged ≤ 10 years. Most cases of AF occur in the mandible, with only a few occurrences in the </span></span>maxilla<span>. Herein, we report a case of AF in the maxilla of an 8-year-old child. In the present case, AF was suggested to have impaired the development of permanent teeth. Regular checkups, including radiographic examinations starting in childhood, may facilitate early detection of lesions in the maxillofacial region.</span></p></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140269209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-03DOI: 10.1016/j.ajoms.2024.02.013
Objective
This study aimed to identify the anatomical characteristics of the posterior alveolar canal (PAC) and related maxillary bone using computed tomography (CT).
Methods
The study included 40 Japanese cadavers (70 hemi-heads), comprising 23 males (41 hemi-heads) and 17 females (29 hemi-heads). Simple CT data of the maxillary bone region of the specimens were obtained and analyzed using a measurement software with reference to the Frankfurt horizontal (FH) plane to identify the PAC in the maxillary tuberosity region, alveolar crest (AC), and corner of the inferior crest of the zygomatic process (CICZP). The shortest distances between the PAC and the respective landmarks and the smallest width of the posterior wall of the maxillary sinus (WPWMS) at the PAC level were calculated and analyzed statistically.
Results
Of all specimens, the mean and SD of AC-PAC: 21.4 ± 3.32 mm, horizontal PAC-CICZP: 15.1 ± 2.89 mm, vertical PAC-CICZP: 5.70 ± 3.15 mm, WPWMS: 0.81 ± 0.31 mm, and the coefficients of variation ranged 15.5–55.3%. In the WPWMS, the mean value was statistically smaller in the female group (0.59 mm) than in the male group (0.96 mm) (p < 0.001).
Conclusions
The results showed certain tendencies in the distances between the PAC and the respective anatomical landmarks with large variations. The thickness of the posterior wall of the maxillary sinus was thinner in females than in males. However, it is < 1 mm in both sexes, and external forces caused by trauma or surgery may fracture the posterior wall of the maxillary sinus and damage the posterior superior alveolar artery regardless of sex.
{"title":"Anatomical study on the posterior alveolar canal in maxillary tuberosity region using computed tomography","authors":"","doi":"10.1016/j.ajoms.2024.02.013","DOIUrl":"10.1016/j.ajoms.2024.02.013","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to identify the anatomical characteristics of the posterior alveolar canal (PAC) and related maxillary bone using computed tomography (CT).</p></div><div><h3>Methods</h3><p>The study included 40 Japanese cadavers (70 hemi-heads), comprising 23 males (41 hemi-heads) and 17 females (29 hemi-heads). Simple CT data of the maxillary bone region of the specimens were obtained and analyzed using a measurement software with reference to the Frankfurt horizontal (FH) plane to identify the PAC in the maxillary tuberosity region, alveolar crest (AC), and corner of the inferior crest of the zygomatic process (CICZP). The shortest distances between the PAC and the respective landmarks and the smallest width of the posterior wall of the maxillary sinus (WPWMS) at the PAC level were calculated and analyzed statistically.</p></div><div><h3>Results</h3><p>Of all specimens, the mean and SD of AC-PAC: 21.4 ± 3.32 mm, horizontal PAC-CICZP: 15.1 ± 2.89 mm, vertical PAC-CICZP: 5.70 ± 3.15 mm, WPWMS: 0.81 ± 0.31 mm, and the coefficients of variation ranged 15.5–55.3%. In the WPWMS, the mean value was statistically smaller in the female group (0.59 mm) than in the male group (0.96 mm) (p < 0.001).</p></div><div><h3>Conclusions</h3><p>The results showed certain tendencies in the distances between the PAC and the respective anatomical landmarks with large variations. The thickness of the posterior wall of the maxillary sinus was thinner in females than in males. However, it is < 1 mm in both sexes, and external forces caused by trauma or surgery may fracture the posterior wall of the maxillary sinus and damage the posterior superior alveolar artery regardless of sex.</p></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140083180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-03DOI: 10.1016/j.ajoms.2024.03.002
Intravascular papillary endothelial hyperplasia (IPEH) is a benign lesion characterized by reactive proliferation of endothelial cells with papillary formations related to thrombosed blood vessels. IPEH in the oral region is relatively rare, and its clinical picture is not specific. Herein, we report the case of a patient with IPEH of the upper lip who had a favorable outcome. A man in his 40 s presented to our department with a nodule beneath the right upper labial mucosa. Magnetic resonance imaging showed a relatively well-defined mass. Based on the diagnosis of a benign tumor, a total excision with healthy margins was performed. Histopathological and immunohistochemical findings revealed a pure form of IPEH with a Ki-67 labeling index of 20%. No recurrence was observed 1 year postoperatively. Although IPEH in the oral region is relatively rare, and its clinical presentation is nonspecific, based on the clinical diagnosis of benign tumors, adequate excision with clear margins can reduce the risk of recurrence. As Ki-67 can be used to predict the biological behavior and risk of IPEH recurrence, careful follow-up considering the risk of recurrence suggested by the Ki-67 labeling index is needed. Thorough knowledge of IPEH is important for clinicians and pathologists to arrive at a correct diagnosis, which leads to appropriate treatment.
{"title":"Intravascular papillary endothelial hyperplasia of the upper lip","authors":"","doi":"10.1016/j.ajoms.2024.03.002","DOIUrl":"10.1016/j.ajoms.2024.03.002","url":null,"abstract":"<div><p><span><span>Intravascular papillary endothelial hyperplasia<span> (IPEH) is a benign lesion characterized by reactive proliferation of endothelial cells with papillary formations related to thrombosed blood vessels. IPEH in the oral region is relatively rare, and its clinical picture is not specific. Herein, we report the case of a patient with IPEH of the upper lip who had a favorable outcome. A man in his 40 s presented to our department with a nodule beneath the right upper labial </span></span>mucosa. Magnetic resonance imaging showed a relatively well-defined mass. Based on the diagnosis of a </span>benign tumor<span>, a total excision with healthy margins was performed. Histopathological and immunohistochemical findings revealed a pure form of IPEH with a Ki-67 labeling index of 20%. No recurrence was observed 1 year postoperatively. Although IPEH in the oral region is relatively rare, and its clinical presentation is nonspecific, based on the clinical diagnosis of benign tumors, adequate excision with clear margins can reduce the risk of recurrence. As Ki-67 can be used to predict the biological behavior and risk of IPEH recurrence, careful follow-up considering the risk of recurrence suggested by the Ki-67 labeling index is needed. Thorough knowledge of IPEH is important for clinicians and pathologists to arrive at a correct diagnosis, which leads to appropriate treatment.</span></p></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140085782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-29DOI: 10.1016/j.ajoms.2024.02.007
Objectives
To investigate the use of an oral moisture meter to aid in the diagnosis of Sjögren’s syndrome (SS) by measuring the moisture values and salivary flow rate (SFR) simultaneously.
Methods
The SFR and moisture values of the dorsum of the tongue and buccal mucosa were measured in 40 patients with SS and 29 healthy controls using an oral moisture meter. In addition, a visual analogue scale (VAS) was used to determine the degree of subjective oral symptoms (xerostomia, decreased saliva production, drinking during eating, oral pain, dysphagia, and dysgeusia).
Results
The moisture values of the dorsum of the tongue and buccal mucosa were significantly lower in SS patients than in healthy subjects (both p < 0.01). SFR, especially when measured by the spitting test, correlated positively with the moisture values of the dorsum of the tongue (p < 0.0001) and buccal mucosa (p < 0.0003). Furthermore, the sensitivity, specificity, and accuracy of the oral moisture meter measurements of the dorsum of the tongue and buccal mucosa were 92.5%, 68.9%, and 82.6%, and 70.0%, 82.8%, and 73.9%, respectively. The moisture values of the dorsum of the tongue had a moderate negative correlation with the VAS scores of secondary subjective oral symptoms of xerostomia (oral pain, dysphagia, and dysgeusia), whereas a weak negative correlation was observed for subjective oral symptoms directly related to xerostomia (xerostomia and decreased saliva production).
Conclusions
The oral moisture meter accurately reflected the results of the SFR tests and chronic subjective oral symptoms, and therefore might be a diagnostic criterion for SS.
方法 使用口腔湿度计测量 40 名斯约戈伦综合征(SS)患者和 29 名健康对照者的舌背和口腔粘膜的唾液流速(SFR)和湿度值。结果 SS 患者的舌背和颊粘膜湿度值明显低于健康人(P 均为 0.01)。SFR与舌背水分值(p <0.0001)和口腔粘膜水分值(p <0.0003)呈正相关,尤其是通过吐痰试验测量时。此外,口腔湿度计测量舌背和口腔黏膜的灵敏度、特异性和准确性分别为 92.5%、68.9% 和 82.6%,以及 70.0%、82.8% 和 73.9%。舌背的湿度值与口腔干燥症继发性主观口腔症状(口腔疼痛、吞咽困难和吞咽困难)的 VAS 评分呈中度负相关,而与口腔干燥症直接相关的主观口腔症状(口腔干燥症和唾液分泌减少)则呈弱负相关。
{"title":"The utility of oral moisture measurement for the diagnosis of Sjögren’s syndrome: Its potential application as a diagnostic criterion","authors":"","doi":"10.1016/j.ajoms.2024.02.007","DOIUrl":"10.1016/j.ajoms.2024.02.007","url":null,"abstract":"<div><h3>Objectives</h3><p>To investigate the use of an oral moisture meter to aid in the diagnosis of Sjögren’s syndrome (SS) by measuring the moisture values and salivary flow rate (SFR) simultaneously.</p></div><div><h3>Methods</h3><p>The SFR and moisture values of the dorsum of the tongue and buccal mucosa were measured in 40 patients with SS and 29 healthy controls using an oral moisture meter. In addition, a visual analogue scale (VAS) was used to determine the degree of subjective oral symptoms (xerostomia, decreased saliva production, drinking during eating, oral pain, dysphagia, and dysgeusia).</p></div><div><h3>Results</h3><p>The moisture values of the dorsum of the tongue and buccal mucosa were significantly lower in SS patients than in healthy subjects (both <em>p</em> < 0.01). SFR, especially when measured by the spitting test, correlated positively with the moisture values of the dorsum of the tongue (<em>p</em> < 0.0001) and buccal mucosa (<em>p</em> < 0.0003). Furthermore, the sensitivity, specificity, and accuracy of the oral moisture meter measurements of the dorsum of the tongue and buccal mucosa were 92.5%, 68.9%, and 82.6%, and 70.0%, 82.8%, and 73.9%, respectively. The moisture values of the dorsum of the tongue had a moderate negative correlation with the VAS scores of secondary subjective oral symptoms of xerostomia (oral pain, dysphagia, and dysgeusia), whereas a weak negative correlation was observed for subjective oral symptoms directly related to xerostomia (xerostomia and decreased saliva production).</p></div><div><h3>Conclusions</h3><p>The oral moisture meter accurately reflected the results of the SFR tests and chronic subjective oral symptoms, and therefore might be a diagnostic criterion for SS.</p></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221255582400019X/pdfft?md5=58510ca1717972fd1085b9ef3482efa4&pid=1-s2.0-S221255582400019X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140470263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-28DOI: 10.1016/j.ajoms.2024.02.011
Aquagenic urticaria is a very rare form of physical urticaria with less than 50 cases reported in the medical literature. The condition causes itchy and potentially painful hives to break out whenever the sufferer comes into contact with water, sweat, or tears. A relationship between chronic urticaria and systemic lupus erythematosus (SLE) has been suggested in the literature. However, aquagenic urticaria has rarely been reported in association with other systemic conditions and is not typically a life-threatening condition. There are no documented cases of aquagenic urticaria occurring together with SLE or small vessel vasculitis, or presenting with cutaneous lesions more serious than urticaric wheals. This report presents a rare case of a 43-year-old African-American woman with aquagenic urticaria, who developed unusually painful skin ulcerations and life-threatening wheezing after contact with water, remained misdiagnosed for over five years, and, subsequently developed several serious comorbidities, including SLE. The case seems to suggest that aquagenic urticaria, urticarial vasculitis, and SLE may be related disorders that potentially developed along one spectrum of disease. As diagnosis of the condition is challenging and the use of water intraorally is essential to performing most dental procedures, the article aims to raise awareness of the condition among dentists and physicians and provides tips and suggestions to help manage patients with aquagenic urticaria more effectively.
{"title":"Aquagenic urticaria associated with anaphylaxis, urticarial vasculitis, skin ulcerations, and systemic lupus erythematosus: A rare case study","authors":"","doi":"10.1016/j.ajoms.2024.02.011","DOIUrl":"10.1016/j.ajoms.2024.02.011","url":null,"abstract":"<div><p><span><span>Aquagenic urticaria<span> is a very rare form of physical urticaria with less than 50 cases reported in the medical literature. The condition causes itchy and potentially painful hives to break out whenever the sufferer comes into contact with water, </span></span>sweat, or tears. A relationship between </span>chronic urticaria<span><span><span> and systemic lupus erythematosus (SLE) has been suggested in the literature. However, aquagenic urticaria has rarely been reported in association with other systemic conditions and is not typically a life-threatening condition. There are no documented cases of aquagenic urticaria occurring together with SLE or </span>small vessel vasculitis<span>, or presenting with cutaneous lesions more serious than urticaric wheals. This report presents a rare case of a 43-year-old African-American woman with aquagenic urticaria, who developed unusually painful </span></span>skin ulcerations<span><span> and life-threatening wheezing after contact with water, remained misdiagnosed for over five years, and, subsequently developed several serious comorbidities, including SLE. The case seems to suggest that aquagenic urticaria, </span>urticarial vasculitis<span>, and SLE may be related disorders that potentially developed along one spectrum of disease. As diagnosis of the condition is challenging and the use of water intraorally is essential to performing most dental procedures, the article aims to raise awareness of the condition among dentists and physicians and provides tips and suggestions to help manage patients with aquagenic urticaria more effectively.</span></span></span></p></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140469334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}