Pub Date : 2019-09-01DOI: 10.1007/s11516-019-0021-9
Zhixin Su, Jody Dunlap, Huixian Xia, Jian Wang, Dandan Mao
{"title":"Portraits of Principals in Chinese Urban and Rural Schools: A Comparative Analysis","authors":"Zhixin Su, Jody Dunlap, Huixian Xia, Jian Wang, Dandan Mao","doi":"10.1007/s11516-019-0021-9","DOIUrl":"https://doi.org/10.1007/s11516-019-0021-9","url":null,"abstract":"","PeriodicalId":45075,"journal":{"name":"中国教育学前沿","volume":"14 1","pages":"422 - 452"},"PeriodicalIF":2.8,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11516-019-0021-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48648839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-01DOI: 10.1007/s11516-019-0022-8
Haiqin Liu, Fred Dervin, Hui Xu, R. Moloney
{"title":"“They Have It Better There”: Chinese Immigrant Teachers’ Beliefs, Ideologies and Imaginaries in Cross-National Comparisons","authors":"Haiqin Liu, Fred Dervin, Hui Xu, R. Moloney","doi":"10.1007/s11516-019-0022-8","DOIUrl":"https://doi.org/10.1007/s11516-019-0022-8","url":null,"abstract":"","PeriodicalId":45075,"journal":{"name":"中国教育学前沿","volume":"14 1","pages":"453 - 479"},"PeriodicalIF":2.8,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11516-019-0022-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46206135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-01DOI: 10.1007/s11516-019-0019-3
Peter Tze Ming Ng
{"title":"Resurgence of the Study of China’s Christian Higher Education since 1980s","authors":"Peter Tze Ming Ng","doi":"10.1007/s11516-019-0019-3","DOIUrl":"https://doi.org/10.1007/s11516-019-0019-3","url":null,"abstract":"","PeriodicalId":45075,"journal":{"name":"中国教育学前沿","volume":"14 1","pages":"364 - 386"},"PeriodicalIF":2.8,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11516-019-0019-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44790722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-01DOI: 10.1007/s11516-019-0025-5
W. Ye, Huijie Chen
{"title":"Education policy functioning in rural society: Ethnography of “minban” teachers in M county","authors":"W. Ye, Huijie Chen","doi":"10.1007/s11516-019-0025-5","DOIUrl":"https://doi.org/10.1007/s11516-019-0025-5","url":null,"abstract":"","PeriodicalId":45075,"journal":{"name":"中国教育学前沿","volume":"14 1","pages":"513 - 515"},"PeriodicalIF":2.8,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11516-019-0025-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53123211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Agnese Gugliandolo, Luigi Chiricosta, Serena Silvestro, Placido Bramanti, Emanuela Mazzon
Alzheimer's disease (AD) is the most common form of dementia worldwide. The hallmarks of AD are the extracellular amyloid plaques, which are formed by amyloid β (Aβ) aggregates derived from the processing of the amyloid precursor protein (APP), and the intraneuronal neurofibrillary tangles, which are formed by the hyperphosphorylated tau protein. The aim of this work was to study the effects of α-tocopherol in retinoic acid differentiated SH-SY5Y neuroblastoma cells exposed to Aβ1-42 evaluating the transcriptional profile by next-generation sequencing. We observed that α-tocopherol was able to reduce the cytotoxicity induced by Aβ treatment, as demonstrated by Thiazolyl Blue Tetrazolium Bromide (MTT) assay. Moreover, the transcriptomic analysis evidenced that α-tocopherol treatment upregulated genes involved in the non-amyloidogenic processing of APP, while it downregulated the amyloidogenic pathway. Moreover, α-tocopherol modulated the expression of the genes involved in autophagy and the cell cycle, which are both known to be altered in AD. The treatment with α-tocopherol was also able to reduce oxidative stress, restoring nuclear factor erythroid-derived 2-like 2 (Nrf2) and decreasing inducible nitric oxide synthase (iNOS) levels, as demonstrated by immunocytochemistry.
{"title":"α-Tocopherol Modulates Non-Amyloidogenic Pathway and Autophagy in an In Vitro Model of Alzheimer's Disease: A Transcriptional Study.","authors":"Agnese Gugliandolo, Luigi Chiricosta, Serena Silvestro, Placido Bramanti, Emanuela Mazzon","doi":"10.3390/brainsci9080196","DOIUrl":"10.3390/brainsci9080196","url":null,"abstract":"<p><p>Alzheimer's disease (AD) is the most common form of dementia worldwide. The hallmarks of AD are the extracellular amyloid plaques, which are formed by amyloid β (Aβ) aggregates derived from the processing of the amyloid precursor protein (APP), and the intraneuronal neurofibrillary tangles, which are formed by the hyperphosphorylated tau protein. The aim of this work was to study the effects of α-tocopherol in retinoic acid differentiated SH-SY5Y neuroblastoma cells exposed to Aβ<sub>1-42</sub> evaluating the transcriptional profile by next-generation sequencing. We observed that α-tocopherol was able to reduce the cytotoxicity induced by Aβ treatment, as demonstrated by Thiazolyl Blue Tetrazolium Bromide (MTT) assay. Moreover, the transcriptomic analysis evidenced that α-tocopherol treatment upregulated genes involved in the non-amyloidogenic processing of APP, while it downregulated the amyloidogenic pathway. Moreover, α-tocopherol modulated the expression of the genes involved in autophagy and the cell cycle, which are both known to be altered in AD. The treatment with α-tocopherol was also able to reduce oxidative stress, restoring nuclear factor erythroid-derived 2-like 2 (Nrf2) and decreasing inducible nitric oxide synthase (iNOS) levels, as demonstrated by immunocytochemistry.</p>","PeriodicalId":45075,"journal":{"name":"中国教育学前沿","volume":"14 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2019-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76023919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-01DOI: 10.1007/s11516-019-0011-y
Gaoming Zheng
{"title":"Deconstructing Doctoral Students’ Socialization from an Institutional Logics Perspective: A Qualitative Study of the Socialization of Chinese Doctoral Students in Finland","authors":"Gaoming Zheng","doi":"10.1007/s11516-019-0011-y","DOIUrl":"https://doi.org/10.1007/s11516-019-0011-y","url":null,"abstract":"","PeriodicalId":45075,"journal":{"name":"中国教育学前沿","volume":"14 1","pages":"206 - 233"},"PeriodicalIF":2.8,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11516-019-0011-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43385934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-01DOI: 10.1007/s11516-019-0012-x
H. Li
{"title":"Academic Integration of Chinese Students in Finland and Germany: A Comparative Perspective","authors":"H. Li","doi":"10.1007/s11516-019-0012-x","DOIUrl":"https://doi.org/10.1007/s11516-019-0012-x","url":null,"abstract":"","PeriodicalId":45075,"journal":{"name":"中国教育学前沿","volume":"14 1","pages":"234 - 256"},"PeriodicalIF":2.8,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11516-019-0012-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48273697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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