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Therapeutic Substitution in Response to Patent Expiry? Statins in Australia* 专利到期后的治疗替代?他汀类药物在澳大利亚*
IF 0.9 Q2 Economics, Econometrics and Finance Pub Date : 2023-12-09 DOI: 10.1111/1759-3441.12407
Christopher Bates, Susan J. Méndez

This study aims to investigate the effects of generic entry on the market share of different statins. We use administrative records from a representative sample of Australians between 2003 and 2014 and analyse over 21 million prescriptions to quantify the change in the total market share of each statin after experiencing generic entry for the first time. With detailed information on patients' benefits and prices, we also estimate potential savings from increasing the use of statins where generics became available. Our results indicate that despite the price decrease, the market share of the molecule experiencing generic entry does not significantly increase, and there is some evidence of substitution away from statins with generic availability. For the most commonly used molecules, this association is stronger in patients receiving higher government subsidies. We calculate potential savings of A$17 million if patients had initiated treatment with the most prescribed off-patent statin rather than a patent-protected statin. Generic entry after patent expiry presents an opportunity for a significant reduction in pharmaceutical expenditure if these are preferred. This study highlights the importance of improving prescription systems that help doctors recommend lower cost, clinically appropriate alternatives and enhance the effectiveness of policies promoting generic substitution.

本研究旨在探讨仿制药进入对不同他汀类药物市场份额的影响。我们使用2003年至2014年间澳大利亚代表性样本的行政记录,分析了2100多万张处方,以量化每种他汀类药物首次进入仿制药后总市场份额的变化。有了关于患者利益和价格的详细信息,我们还估计了在有仿制药的地方增加他汀类药物使用可能节省的费用。我们的研究结果表明,尽管价格下降,但进入仿制药市场的分子的市场份额并没有显著增加,而且有一些证据表明他汀类药物的替代与仿制药的可用性。对于最常用的分子,这种关联在接受较高政府补贴的患者中更为明显。我们计算出,如果患者开始使用处方最多的非专利他汀类药物而不是专利保护的他汀类药物治疗,可能节省1700万澳元。专利到期后进入仿制药提供了一个机会,显着减少医药支出,如果这些是首选的。这项研究强调了改善处方系统的重要性,它可以帮助医生推荐成本更低、临床合适的替代方案,并提高促进仿制药替代政策的有效性。
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引用次数: 0
Do Child Marriage Programs Help Girls Weather Shocks Like COVID-19? Evidence from the More Than Brides Alliance Intervention* 童婚计划是否有助于女孩抵御 COVID-19 等冲击?来自 "不只是新娘联盟 "干预措施的证据*。
IF 0.9 Q2 Economics, Econometrics and Finance Pub Date : 2023-11-22 DOI: 10.1111/1759-3441.12406
Andrea J. Melnikas, Grace Saul, Neelanjana Pandey, Momoe Makino, Sajeda Amin, Michelle Chau

This paper contributes to the evidence base on the impact of the COVID-19 on child marriage prevalence and on the protective potential of girl-centred, community-level interventions in buffering communities against aggregate shocks. Drawing on data from repeat cross-sectional surveys completed with adolescent girls aged 12–19 in 609 villages in four states in India as a part of the More Than Brides Alliance impact evaluation, we examine whether the intervention appears to have impacted child marriage prevalence over its 5-year implementation period, whether the onset of COVID-19 affected ongoing trends in child marriage prevalence, and whether the intervention appeared to have buffered against increased child marriage risk resulting from the pandemic. Results show that significant differences emerged between treatment and control villages between midline and endline—and these differences were larger following the onset of COVID-19—suggesting both that the treatment was successful in preventing child marriage and that the intervention had a protective effect. Results suggest that girl-centred, community-based interventions can help communities to weather environmental shocks and protect girls against potential increased child marriage risk during times of acute crisis.

本文为 COVID-19 对童婚率的影响以及以女孩为中心的社区级干预措施在缓冲社区总体冲击方面的保护潜力提供了证据基础。作为 "比新娘更重要联盟 "影响评估的一部分,我们利用对印度四个邦 609 个村庄 12-19 岁少女进行的重复横截面调查数据,研究了干预措施在 5 年实施期间是否对童婚流行率产生了影响,COVID-19 的爆发是否影响了童婚流行率的持续趋势,以及干预措施是否对大流行病导致的童婚风险增加起到了缓冲作用。结果表明,在中线和终点之间,治疗村和对照村之间出现了明显的差异,而且这些差异在 COVID-19 爆发后更大,这表明治疗在预防童婚方面是成功的,而且干预措施具有保护作用。结果表明,以女孩为中心、基于社区的干预措施可以帮助社区抵御环境冲击,并在严重危机时期保护女孩免受可能增加的童婚风险。
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引用次数: 2
Does Stress Make You Less Neighbourly?* 压力是否会降低你的邻里关系?
IF 0.9 Q2 Economics, Econometrics and Finance Pub Date : 2023-11-08 DOI: 10.1111/1759-3441.12405
Anna Ploszaj

Social cohesion and financial tensions are the key components of psychosocial well-being, yet the relationship has rarely been examined. This article, which offers an empirical investigation into the complex and multidimensional character of social cohesion, examines how financial stress affects social relations in Australia and analyses the moderating effect of social support using longitudinal data from the Household, Income and Labour Dynamics in Australia (HILDA) survey. The results indicate that financial stress has negative effects on social cohesion and has the potential to contribute to social fragmentation. It was found that structural social cohesion is more affected by financial stress than cognitive social cohesion. This study also uncovers the beneficial and buffering effects that social support can bestow on financial stress trauma sufferers.

社会凝聚力和财务紧张是社会心理健康的重要组成部分,但两者之间的关系却鲜有研究。本文利用澳大利亚家庭、收入和劳动力动态调查(HILDA)的纵向数据,对社会凝聚力的复杂性和多维性进行了实证研究,探讨了经济压力如何影响澳大利亚的社会关系,并分析了社会支持的调节作用。结果表明,经济压力会对社会凝聚力产生负面影响,并有可能导致社会分裂。研究发现,与认知社会凝聚力相比,结构社会凝聚力受经济压力的影响更大。这项研究还揭示了社会支持对经济压力创伤患者的有益和缓冲作用。
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引用次数: 0
Evaluating the Role of GDP Per Capita, Air Pollution and Non-Economic Factors in Determining Health Expenditure: Evidence from Asian Region Using Instrumental Variables Techniques 评估人均 GDP、空气污染和非经济因素在决定卫生支出中的作用:使用工具变量技术分析亚洲地区的证据
IF 0.9 Q2 Economics, Econometrics and Finance Pub Date : 2023-10-14 DOI: 10.1111/1759-3441.12404
Samia Nasreen, Aviral Kumar Tiwari, Mehr-un Nisa, Faryal Ishtiaq

This study investigates the effect of income per capita, air pollution and healthcare services on health expenditure in Asian economies using annual data from 1995 to 2018. The determinants of total health expenditure and public and private sector health expenditures are estimated separately. The Generalised Methods of Moment (GMM) and Instrument Variable Quantile Panel Regression (IVQPR) techniques are employed in this study. The results explain that environmental pollution, the price of health care, urbanisation and the number of hospital beds have positive effects on total health expenditures as well as on public and private health expenditures. Interestingly, income per capita has a negative effect on health expenditure at lower quantiles and a positive at higher quantiles. The proportion of the elderly population has an adverse effect on total health expenditure, while life expectancy shows a positive effect at lower quantiles and a negative effect at higher quantiles on health expenditure. The impact of the number of physicians per capita is found to be negative and significant, while the availability of safe drinking water and education demonstrates a positive effect on health expenditure. Out-of-pocket expenditure and technological progress are positively associated with health expenditure. Smoking is a significant determinant of government health expenditure, but it is difficult to determine the trend of smoking prevalence in Asian economies. The outcomes of this study provide some important insights to policymakers, which can be used to design a more efficient healthcare sector in Asian countries.

本研究利用 1995 年至 2018 年的年度数据,调查了人均收入、空气污染和医疗保健服务对亚洲经济体卫生支出的影响。研究分别估算了卫生总支出、公共和私营部门卫生支出的决定因素。本研究采用了广义矩方法(GMM)和工具变量量级面板回归(IVQPR)技术。结果表明,环境污染、医疗保健价格、城市化和医院床位数对总医疗支出以及公共和私人医疗支出有积极影响。有趣的是,人均收入在较低的分位数上对医疗支出有负面影响,而在较高的分位数上则有正面影响。老年人口的比例对医疗总支出有不利影响,而预期寿命对医疗支出的影响在较低的量化值上为正,在较高的量化值上为负。人均医生数量对医疗支出的影响为负且显著,而安全饮用水和教育对医疗支出的影响为正。自付支出和技术进步与医疗支出呈正相关。吸烟是政府卫生支出的一个重要决定因素,但很难确定亚洲经济体的吸烟率趋势。本研究的结果为政策制定者提供了一些重要启示,可用于设计亚洲国家更有效的医疗保健部门。
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引用次数: 0
The Economic Public Interest in a World of Oligopoly* 寡头垄断世界中的经济公共利益*
IF 0.9 Q2 Economics, Econometrics and Finance Pub Date : 2023-09-29 DOI: 10.1111/1759-3441.12403
Ross Garnaut

The Australian economy has performed well compared with comparable countries over the last three decades only if we average the excellent performance in the 1990s and the poor performance over the past decade. Real wages over the past decade have stagnated—to an extent without historical parallel. We cannot understand the economy's underperformance without recognising the increasing claims of economic rents on national income. Correction of weaknesses requires coordination of many policy instruments including measures to reduce the prevalence of rents (competition policy and regulation of oligopoly where competition is not feasible or inefficient) and changes in taxation arrangements to shift the burden of business taxation from firms in competitive activities to firms relying heavily on economic rents.

与同类国家相比,澳大利亚经济在过去三十年中表现出色,但前提是我们必须将上世纪九十年代的出色表现和过去十年的糟糕表现平均起来。在过去十年中,实际工资停滞不前,这是历史上从未有过的。如果不认识到经济租金对国民收入的要求越来越高,我们就无法理解经济表现不佳的原因。要纠正这些弱点,就必须协调多种政策手段,包括减少租金的措施(竞争政策和在竞争不可行或效率低下时对寡头垄断的管制),以及改变税收安排,将商业税收负担从从事竞争活动的公司转移到严重依赖经济租金的公司。
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引用次数: 0
Learning Losses of Undergraduate Students in South Asia during COVID-19 and its Determinants* COVID-19 期间南亚本科生的学习损失及其决定因素*
IF 0.9 Q2 Economics, Econometrics and Finance Pub Date : 2023-08-14 DOI: 10.1111/1759-3441.12402
Farzin Mumtahena, Kaustav Sen, Mahnoor Imran Sayyed, Pasan Wijayawardhana, Roya Zafari, Shrijya Kafle

The COVID-19 pandemic has brought about significant changes to the the learning process, prompted by the shift away from traditional physical classrooms to virtual ones. With unequal access to remote learning technologies, there are concerns regarding undergraduate students' academic progress. A primary survey was conducted to create a composite learning score to quantify learning losses. A significantly higher learning loss is visible among students belonging to families facing income losses during the pandemic, and public university students. We find that compared to India, students of Bangladesh and Pakistan are affected more severely in terms of learning losses. The article also measures the extent of psychological distress and academic demotivation related to online learning. We find that the same groups of students face higher psychological distress and academic demotivation.

COVID-19 大流行给学习过程带来了重大变化,从传统的实体教室转向虚拟教室。由于使用远程学习技术的机会不平等,本科生的学业进展令人担忧。我们进行了一项初步调查,以创建一个综合学习分数来量化学习损失。在大流行病期间面临收入损失的家庭的学生和公立大学的学生中,学习损失明显较高。我们发现,与印度相比,孟加拉国和巴基斯坦的学生受到的学习损失影响更为严重。文章还测量了与在线学习相关的心理压力和学习动力的程度。我们发现,同样的学生群体面临着更高的心理压力和学习动力。
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引用次数: 0
Digitalisation, Exports, Government Support and Firms' Finances during the COVID-19 Pandemic: Evidence from Central and Eastern Europe* COVID-19 大流行期间的数字化、出口、政府支持和企业财务:来自中欧和东欧的证据*
IF 0.9 Q2 Economics, Econometrics and Finance Pub Date : 2023-08-12 DOI: 10.1111/1759-3441.12401
Hazwan Haini, Syaza Borhanudin, Pang Wei Loon

This study examines whether digital technologies and exporting activities are associated with the likelihood of bankruptcy, liquidity issues and overdue financial obligations during the COVID-19 pandemic. Restrictive measures and lockdowns during the pandemic led to the loss of revenue while incurring costs, resulting in financial issues. Using a sample of 8633 firms from the Central and Eastern economies, we estimate a logistic model and find the following: digitalisation is associated with a decrease in the likelihood of liquidity issues and overdue financial issues; exporting firms experience similar financial outcomes to non-exporting firms; firms that expect or receive government support are associated with an increase in the probability of facing financial issues. Policy implications are discussed.

本研究探讨了在 COVID-19 大流行期间,数字技术和出口活动是否与破产、流动性问题和逾期财务债务的可能性有关。大流行病期间的限制性措施和封锁导致了收入损失,同时也产生了成本,造成了财务问题。我们以中东部经济体的 8633 家企业为样本,对一个逻辑模型进行了估计,结果发现:数字化与出现流动性问题和逾期财务问题的可能性降低有关;出口企业的财务结果与非出口企业相似;期望或接受政府支持的企业面临财务问题的可能性增加。讨论了政策影响。
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引用次数: 0
Hope Springs Eternal: Plurilaterals, the WTO and APEC* 希望永存:多边、世贸组织和亚太经合组织*
IF 0.9 Q2 Economics, Econometrics and Finance Pub Date : 2023-08-06 DOI: 10.1111/1759-3441.12400
Craig Emerson

The rules-based international trading system is under the greatest pressure since its inception in 1948 when the General Agreement on Tariffs and Trade (GATT) came into force. The rules of the GATT's successor, the World Trade Organization (WTO), are being flouted, and the Appellate Body of the dispute-settlement system is no longer functioning. Superpower rivalry is likely to prevent new multilateral trade negotiations leading to substantive agreements. In these circumstances, like-minded countries should begin negotiating plurilateral agreements at the WTO and within APEC.

自 1948 年《关税及贸易总协定》(关贸总协定)生效以来,以规则为基础的国际贸易体系正面临着最大的压力。关贸总协定的继承者世界贸易组织(WTO)的规则正遭到蔑视,争端解决体系的上诉机构已不再发挥作用。超级大国之间的竞争很可能阻碍新的多边贸易谈判达成实质性协议。在这种情况下,志同道合的国家应开始在世贸组织和亚太经合组织内谈判诸边协议。
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引用次数: 0
Entrepreneurial Risk and Digital Financial Inclusion: A Cross-Country Analysis 创业风险与数字金融普惠:跨国分析
IF 0.9 Q2 Economics, Econometrics and Finance Pub Date : 2023-07-13 DOI: 10.1111/1759-3441.12399
Comlanvi Martin Konou

The inception of financial technologies (Fintech) has enabled expanded use of financial services. Fintech contributes to financial inclusion and by doing so provides impacts on income inequality, poverty and economic growth. A prospective route of influence exerted by Fintech is to assist economic agents in taking entrepreneurial risks. The purpose of this study was to investigate the impact of digital financial inclusion, as enhanced by FinTech, on entrepreneurial risk. An index for measuring levels of digital financial inclusion was constructed based on variation patterns in several indicators of digital activities. A cross-country model was proposed that relates entrepreneurial risk to digital financial inclusion as well as to a variety of other economic and social factors. Estimation results based on a panel of countries show that digital financial inclusion (0.265), institutional quality (0.169), per capita GDP (0.0456) and education (0.0475) have positive and significant effects on entrepreneurial risk. In contrast, time required to start a business (−0.136) and effective tax rates on capital (−0.494) provide negative and significant effects. In addition, a significant quadratic relationship between entrepreneurial risk and remittances (employee compensation and personal transfers) was found.

金融技术(Fintech)的出现使金融服务的使用得以扩大。金融科技有助于金融包容性,从而对收入不平等、贫困和经济增长产生影响。金融科技施加影响的一个潜在途径是帮助经济主体承担创业风险。本研究的目的是调查金融科技增强的数字金融包容性对创业风险的影响。根据数字活动的几个指标的变化模式,构建了一个衡量数字金融包容性水平的指数。提出了一个跨国模型,将创业风险与数字金融包容性以及各种其他经济和社会因素联系起来。基于一组国家的估计结果显示,数字金融包容性(0.265)、机构质量(0.169)、人均GDP(0.0456)和教育(0.0475)对创业风险有积极而显著的影响。相比之下,创业所需的时间(-0.136)和资本的有效税率(-0.494)会产生负面和显著的影响。此外,创业风险与汇款(员工薪酬和个人转账)之间存在显著的二次关系。
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引用次数: 0
Can Employment Empower Women in Rural India* 就业能否增强印度农村妇女的能力*?
IF 0.9 Q2 Economics, Econometrics and Finance Pub Date : 2023-06-18 DOI: 10.1111/1759-3441.12397
Ayona Bhattacharjee, Jay Dev Dubey

The literature on women empowerment highlights a positive correlation between work and decision-making power of women within families. On the contrary, the role of work opportunities in letting women achieve greater control over their lives, making them more independent is also well-established. In this background, we explore the effect of women employment on different dimensions of women empowerment by using a nationally representative household survey data, the Indian Human Development Survey (IHDS-II, 2011–12). As “empowerment” is unobservable, multi-faceted and difficult to quantify, we model it by an index which aggregates the qualitative answers provided by a respondent. Due to the presence of an endogenous relation, we exploit sources of exogenous variations in employment through an instrumental variable (IV) setup. Following the literature, we identify IV as the level of transport infrastructure in the region where a woman resides. We find that the estimated coefficients are positive and statistically significant, remaining robust to changes in empowerment calculation. In the context of public initiatives aimed at improving female labour force participation and empowering women in India, our results show how policymakers can look beyond standard policies and take the help of transport-related initiatives to improve employment and empowerment.

关于妇女赋权的文献强调了工作与妇女在家庭中的决策权之间的正相关关系。相反,工作机会在让妇女更好地控制自己的生活、使她们更加独立方面的作用也是公认的。在此背景下,我们利用具有全国代表性的家庭调查数据--《印度人类发展调查》(IHDS-II,2011-12 年)--探讨了妇女就业对妇女赋权不同维度的影响。由于 "赋权 "是不可观测的、多方面的且难以量化,因此我们用一个指数对其进行建模,该指数汇总了受访者提供的定性答案。由于存在内生关系,我们通过工具变量(IV)设置来利用就业的外生变化来源。根据文献,我们将 IV 确定为妇女居住地区的交通基础设施水平。我们发现,估计系数为正且在统计上显著,不受赋权计算变化的影响。在旨在提高印度女性劳动力参与率和增强妇女权能的公共倡议背景下,我们的结果表明,决策者可以超越标准政策,利用与交通相关的倡议来改善就业和增强权能。
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引用次数: 0
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