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COVIDAL: A Machine Learning Classifier for Digital COVID-19 Diagnosis in German Hospitals covid:用于德国医院数字COVID-19诊断的机器学习分类器
IF 2.5 Q2 COMPUTER SCIENCE, INFORMATION SYSTEMS Pub Date : 2022-12-24 DOI: 10.1145/3567431
C. Bartenschlager, Stefanie S. Ebel, Sebastian Kling, J. Vehreschild, L. Zabel, C. Spinner, Andreas Schuler, Axel R. Heller, S. Borgmann, Reinhard Hoffmann, S. Rieg, H. Messmann, M. Hower, J. Brunner, F. Hanses, C. Römmele
For the fight against the COVID-19 pandemic, it is particularly important to map the course of infection, in terms of patients who have currently tested SARS-CoV-2 positive, as accurately as possible. In hospitals, this is even more important because resources have become scarce. Although polymerase chain reaction (PCR) and point of care (POC) antigen testing capacities have been massively expanded, they are often very time-consuming and cost-intensive and, in some cases, lack appropriate performance. To meet these challenges, we propose the COVIDAL classifier for AI-based diagnosis of symptomatic COVID-19 subjects in hospitals based on laboratory parameters. We evaluate the algorithm's performance by unique multicenter data with approximately 4,000 patients and an extraordinary high ratio of SARS-CoV-2-positive patients. We analyze the influence of data preparation, flexibility in optimization targets, as well as the selection of the test set on the COVIDAL outcome. The algorithm is compared with standard AI, PCR, POC antigen testing and manual classifications of seven physicians by a decision theoretic scoring model including performance metrics, turnaround times and cost. Thereby, we define health care settings in which a certain classifier for COVID-19 diagnosis is to be applied. We find sensitivities, specificities, and accuracies of the COVIDAL algorithm of up to 90 percent. Our scoring model suggests using PCR testing for a focus on performance metrics. For turnaround times, POC antigen testing should be used. If balancing performance, turnaround times, and cost is of interest, as, for example, in the emergency department, COVIDAL is superior based on the scoring model.
为了抗击新冠肺炎大流行,尽可能准确地绘制目前检测出SARS-CoV-2呈阳性的患者的感染过程尤为重要。在医院,这一点更为重要,因为资源已经变得稀缺。尽管聚合酶链式反应(PCR)和护理点(POC)抗原检测能力已经得到了大规模扩展,但它们往往非常耗时和成本密集,在某些情况下缺乏适当的性能。为了应对这些挑战,我们提出了COVIDAL分类器,用于基于实验室参数对医院中有症状的新冠肺炎受试者进行基于AI的诊断。我们通过对大约4000名患者和极高比例的严重急性呼吸系统综合征冠状病毒2型阳性患者的独特多中心数据来评估该算法的性能。我们分析了数据准备、优化目标的灵活性以及测试集的选择对COVIDAL结果的影响。通过包括绩效指标、周转时间和成本在内的决策论评分模型,将该算法与标准AI、PCR、POC抗原检测和七名医生的手动分类进行了比较。因此,我们定义了应用新冠肺炎诊断的特定分类器的医疗保健设置。我们发现COVIDAL算法的灵敏度、特异性和准确性高达90%。我们的评分模型建议使用PCR测试来关注绩效指标。对于周转时间,应使用POC抗原检测。如果平衡性能、周转时间和成本是有意义的,例如在急诊科,那么根据评分模型,COVIDAL是优越的。
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引用次数: 2
Resource Allocation for Heterogeneous Computing Tasks in Wirelessly Powered MEC-enabled IIOT Systems 支持MEC的IIOT系统中异构计算任务的资源分配
IF 2.5 Q2 COMPUTER SCIENCE, INFORMATION SYSTEMS Pub Date : 2022-11-18 DOI: 10.1145/3571291
Yixiang Hu, Xiaoheng Deng, Congxu Zhu, Xuechen Chen, Laixin Chi
Integrating wireless power transfer with mobile edge computing (MEC) has become a powerful solution for increasingly complicated and dynamic industrial Internet of Things (IIOT) systems. However, the traditional approaches overlooked the heterogeneity of the tasks and the dynamic arrival of energy in wirelessly powered MEC-enabled IIOT systems. In this article, we formulate the problem of maximizing the product of the computing rate and the task execution success rate for heterogeneous tasks. To manage energy harvesting adaptively and select appropriate computing modes, we devise an online resource allocation and computation offloading approach based on deep reinforcement learning. We decompose this approach into two stages: an offloading decision stage and a stopping decision stage. The purpose of the offloading decision stage is to select the computing mode and dynamically allocate the computation round length for each task after learning from the channel state information and the task experience. This stage allows the system to support heterogeneous computing tasks. Subsequently, in the second stage, we adaptively adjust the number of fading slots devoted to energy harvesting in each round in accordance with the status of each fading slot. Simulation results show that our proposed algorithm can better allocate resources for heterogeneous tasks and reduce the ratio of failed tasks and energy consumption when compared with several existing algorithms.
将无线功率传输与移动边缘计算(MEC)集成已成为日益复杂和动态的工业物联网(IIOT)系统的强大解决方案。然而,传统的方法忽略了任务的异质性和无线供电的MEC支持的IIOT系统中能量的动态到达。在本文中,我们公式化了异构任务的计算率和任务执行成功率的乘积最大化问题。为了自适应地管理能量采集并选择合适的计算模式,我们设计了一种基于深度强化学习的在线资源分配和计算卸载方法。我们将这种方法分解为两个阶段:卸载决策阶段和停止决策阶段。卸载决策阶段的目的是在从信道状态信息和任务经验中学习后,为每个任务选择计算模式并动态分配计算循环长度。此阶段允许系统支持异构计算任务。随后,在第二阶段,我们根据每个衰落时隙的状态自适应地调整每轮中用于能量收集的衰落时隙的数量。仿真结果表明,与现有的几种算法相比,我们提出的算法可以更好地为异构任务分配资源,降低失败任务的比例和能耗。
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引用次数: 1
Blockchain Use Case in Ballistics and Crime Gun Tracing and Intelligence: Toward Overcoming Gun Violence 用例在弹道和犯罪枪支追踪和情报:克服枪支暴力
IF 2.5 Q2 COMPUTER SCIENCE, INFORMATION SYSTEMS Pub Date : 2022-11-14 DOI: 10.1145/3571290
Patricia Akello, Naga Vemprala, Nicole Lang Beebe, Kim-Kwang Raymond Choo
In the United States and around the world, gun violence has become a long-standing public safety concern and a security threat, due to violent gun-related crimes, injuries, and fatalities. Although legislators and lawmakers have attempted to mitigate its threats through legislation, research on gun violence confirms the need for a comprehensive approach to gun violence prevention. This entails addressing the problem in as many ways as possible, such as through legislation, new technological advancements, re-engineering supply, and administrative protocols, among others. The research focuses on the technological, supply, and administrative aspects, in which we propose a manner of managing gun-related data efficiently from the point of manufacture/sale, as well as at points of transfers between secondary sellers for the improvement of criminal investigation processes. Making data more readily available with greater integrity will facilitate successful investigations and prosecutions of gun crimes. Currently, there is no single and uniform platform for firearm manufacturers, dealers, and other stakeholders involved in firearm sales, dissemination, management, and investigation. With the help of Blockchain technology, gun registry, ownership, transfers, and, most importantly, investigations, when crimes occur, can all be managed efficiently, breaking the cycle of gun violence. The identification of guns, gun tracing, and identification of gun owners/possessors rely on accuracy, integrity, and consistency in related systems to influence gun crime investigation processes. Blockchain technology, which uses a consensus-based approach to improve processes and transactions, is demonstrated in this study as a way to enhance these procedures. To the best of our knowledge, this is the first study to explore and demonstrate the utility of Blockchain for gun-related criminal investigations using a design science approach.
在美国和世界各地,由于与枪支有关的暴力犯罪、伤害和死亡,枪支暴力已成为一个长期存在的公共安全问题和安全威胁。尽管立法者和立法者试图通过立法来减轻其威胁,但对枪支暴力的研究证实,需要采取全面的方法来预防枪支暴力。这需要以尽可能多的方式解决问题,例如通过立法、新技术进步、重新设计供应和管理协议等。研究集中在技术、供应和管理方面,我们提出了一种有效管理枪支相关数据的方法,从制造/销售点,以及二级卖家之间的转移点,以改善刑事调查过程。使数据更容易获得,更完整,将有助于成功地调查和起诉枪支犯罪。目前,枪支制造商、经销商以及其他涉及枪支销售、传播、管理和调查的利益相关者没有一个统一的平台。在区块链技术的帮助下,当犯罪发生时,枪支登记、所有权、转让,以及最重要的调查,都可以得到有效管理,打破枪支暴力的循环。枪支的识别、枪支追踪和枪支拥有者/持有者的识别依赖于相关系统的准确性、完整性和一致性,以影响枪支犯罪调查过程。区块链技术使用基于共识的方法来改进流程和交易,在本研究中被证明是加强这些程序的一种方式。据我们所知,这是第一个使用设计科学方法探索和证明区块链在枪支相关犯罪调查中的效用的研究。
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引用次数: 1
Roadside Unit-based Unknown Object Detection in Adverse Weather Conditions for Smart Internet of Vehicles 基于路侧单元的智能车联网恶劣天气条件下未知物体检测
IF 2.5 Q2 COMPUTER SCIENCE, INFORMATION SYSTEMS Pub Date : 2022-11-04 DOI: 10.1145/3554923
Yu-Chia Chen, Sin-Ye Jhong, Chih-Hsien Hsia
For Internet of Vehicles applications, reliable autonomous driving systems usually perform the majority of their computations on the cloud due to the limited computing power of edge devices. The communication delay between cloud platforms and edge devices, however, can cause dangerous consequences, particularly for latency-sensitive object detection tasks. Object detection tasks are also vulnerable to significantly degraded model performance caused by unknown objects, which creates unsafe driving conditions. To address these problems, this study develops an orchestrated system that allows real-time object detection and incrementally learns unknown objects in a complex and dynamic environment. A you-only-look-once–based object detection model in edge computing mode uses thermal images to detect objects accurately in poor lighting conditions. In addition, an attention mechanism improves the system’s performance without significantly increasing model complexity. An unknown object detector automatically classifies and labels unknown objects without direct supervision on edge devices, while a roadside unit (RSU)-based mechanism is developed to update classes and ensure a secure driving experience for autonomous vehicles. Moreover, the interactions between edge devices, RSU servers, and the cloud are designed to allow efficient collaboration. The experimental results indicate that the proposed system learns uncategorized objects dynamically and detects instances accurately.
对于车联网应用,由于边缘设备的计算能力有限,可靠的自动驾驶系统通常在云上执行大部分计算。然而,云平台和边缘设备之间的通信延迟可能会造成危险的后果,尤其是对于延迟敏感的对象检测任务。物体检测任务也容易受到未知物体导致的模型性能显著下降的影响,这会造成不安全的驾驶条件。为了解决这些问题,本研究开发了一个协调系统,允许在复杂动态的环境中实时检测对象并逐步学习未知对象。在边缘计算模式下,基于“只看一次”的物体检测模型使用热图像在光线较差的条件下准确检测物体。此外,注意力机制在不显著增加模型复杂性的情况下提高了系统的性能。未知物体检测器在没有边缘设备直接监督的情况下自动对未知物体进行分类和标记,同时开发了一种基于路侧单元(RSU)的机制来更新类别并确保自动驾驶汽车的安全驾驶体验。此外,边缘设备、RSU服务器和云之间的交互旨在实现高效协作。实验结果表明,该系统能动态学习未分类对象,并能准确检测实例。
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引用次数: 3
The Opportunity in Difficulty: A Dynamic Privacy Budget Allocation Mechanism for Privacy-Preserving Multi-dimensional Data Collection 困难中的机遇:一种保护隐私的多维数据收集动态隐私预算分配机制
IF 2.5 Q2 COMPUTER SCIENCE, INFORMATION SYSTEMS Pub Date : 2022-10-29 DOI: 10.1145/3569944
Xue Chen, Cheng Wang, Qing Yang, Teng Hu, Changjun Jiang
Data collection under local differential privacy (LDP) has been gradually on the stage. Compared with the implementation of LDP on the single attribute data collection, that on multi-dimensional data faces great challenges as follows: (1) Communication cost. Multivariate data collection needs to retain the correlations between attributes, which means that more complex privatization mechanisms will result in more communication costs. (2) Noise scale. More attributes have to share the privacy budget limited by data utility and privacy-preserving level, which means that less privacy budget can be allocated to each of them, resulting in more noise added to the data. In this work, we innovatively reverse the complex multi-dimensional attributes, i.e., the major negative factor that leads to the above difficulties, to act as a beneficial factor to improve the efficiency of privacy budget allocation, so as to realize a multi-dimensional data collection under LDP with high comprehensive performance. Specifically, we first present a Multivariate k-ary Randomized Response (kRR) mechanism, called Multi-kRR. It applies the RR directly to each attribute to reduce the communication cost. To deal with the impact of a large amount of noise, we propose a Markov-based dynamic privacy budget allocation mechanism Markov-kRR, which determines the present privacy budget (flipping probability) of an attribute related to the state of the previous attributes. Then, we fix the threshold of flipping times in Markov-kRR and propose an improved mechanism called MarkFixed-kRR, which can obtain more optimized utility by choosing the suitable threshold. Finally, extensive experiments demonstrate the efficiency and effectiveness of our proposed methods.
局部差分隐私(LDP)下的数据采集已逐步走上舞台。与LDP在单属性数据采集上的实现相比,LDP在多维数据上的实现面临着以下巨大挑战:(1)通信成本。多元数据收集需要保留属性之间的相关性,这意味着更复杂的私有化机制将导致更多的通信成本。(2) 噪音等级。更多的属性必须共享受数据实用性和隐私保护级别限制的隐私预算,这意味着可以为每个属性分配更少的隐私预算。这会给数据添加更多的噪声。在这项工作中,我们创新性地扭转了复杂的多维属性,即导致上述困难的主要负面因素,作为提高隐私预算分配效率的有利因素,从而实现LDP下的高综合性能多维数据收集。具体来说,我们首先提出了一种多变量k元随机反应(kRR)机制,称为多kRR。它将RR直接应用于每个属性,以降低通信成本。为了应对大量噪声的影响,我们提出了一种基于马尔可夫的动态隐私预算分配机制Markov kRR,该机制确定与先前属性的状态相关的属性的当前隐私预算(翻转概率)。然后,我们在Markov kRR中固定了翻转次数的阈值,并提出了一种改进的机制MarkFixed kRR,通过选择合适的阈值可以获得更优化的效用。最后,大量的实验证明了我们提出的方法的有效性和有效性。
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引用次数: 3
Tackling the Accuracy-Interpretability Trade-off: Interpretable Deep Learning Models for Satellite Image-based Real Estate Appraisal 解决精度-可解释性权衡:基于卫星图像的房地产评估的可解释深度学习模型
IF 2.5 Q2 COMPUTER SCIENCE, INFORMATION SYSTEMS Pub Date : 2022-10-10 DOI: 10.1145/3567430
Jan-Peter Kucklick, Oliver Müller
Deep learning models fuel many modern decision support systems, because they typically provide high predictive performance. Among other domains, deep learning is used in real-estate appraisal, where it allows extending the analysis from hard facts only (e.g., size, age) to also consider more implicit information about the location or appearance of houses in the form of image data. However, one downside of deep learning models is their intransparent mechanic of decision making, which leads to a trade-off between accuracy and interpretability. This limits their applicability for tasks where a justification of the decision is necessary. Therefore, in this article, we first combine different perspectives on interpretability into a multi-dimensional framework for a socio-technical perspective on explainable artificial intelligence. Second, we measure the performance gains of using multi-view deep learning, which leverages additional image data (satellite images) for real estate appraisal. Third, we propose and test a novel post hoc explainability method called Grad-Ram. This modified version of Grad-Cam mitigates the intransparency of convolutional neural networks for predicting continuous outcome variables. With this, we try to reduce the accuracy-interpretability trade-off of multi-view deep learning models. Our proposed network architecture outperforms traditional hedonic regression models by 34% in terms of MAE. Furthermore, we find that the used satellite images are the second most important predictor after square feet in our model and that the network learns interpretable patterns about the neighborhood structure and density.
深度学习模型为许多现代决策支持系统提供动力,因为它们通常提供高预测性能。在其他领域中,深度学习被用于房地产评估,它允许将分析从硬事实(例如,大小,年龄)扩展到以图像数据的形式考虑更多关于房屋位置或外观的隐含信息。然而,深度学习模型的一个缺点是它们的决策机制不透明,这导致了准确性和可解释性之间的权衡。这限制了它们在需要对决策进行证明的任务中的适用性。因此,在本文中,我们首先将关于可解释性的不同观点结合到一个多维框架中,以社会技术视角来研究可解释性人工智能。其次,我们测量了使用多视图深度学习的性能增益,它利用额外的图像数据(卫星图像)进行房地产评估。第三,我们提出并测试了一种新的事后可解释性方法,称为Grad-Ram。这种改进版本的Grad-Cam减轻了卷积神经网络预测连续结果变量的不透明性。因此,我们试图减少多视图深度学习模型的准确性和可解释性之间的权衡。我们提出的网络架构在MAE方面优于传统的享乐回归模型34%。此外,我们发现使用的卫星图像是我们模型中仅次于平方英尺的第二个最重要的预测因子,并且网络学习了关于社区结构和密度的可解释模式。
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引用次数: 1
Examining Disease Multimorbidity in U.S. Hospital Visits Before and During COVID-19 Pandemic: A Graph Analytics Approach 新冠肺炎大流行前和期间美国医院就诊的疾病多发病率研究:图形分析方法
IF 2.5 Q2 COMPUTER SCIENCE, INFORMATION SYSTEMS Pub Date : 2022-09-27 DOI: 10.1145/3564274
Karthik Srinivasan, Jinhang Jiang
Enduring effects of the COVID-19 pandemic on healthcare systems can be preempted by identifying patterns in diseases recorded in hospital visits over time. Disease multimorbidity or simultaneous occurrence of multiple diseases is a growing global public health challenge as populations age and long-term conditions become more prevalent. We propose a graph analytics framework for analyzing disease multimorbidity in hospital visits. Within the framework, we propose a graph model to explain multimorbidity as a function of prevalence, category, and chronic nature of the underlying disease. We apply our model to examine and compare multimorbidity patterns in public hospitals in Arizona, U.S., during five six-month time periods before and during the pandemic. We observe that while multimorbidity increased by 34.26% and 41.04% during peak pandemic for mental disorders and respiratory disorders respectively, the gradients for endocrine diseases and circulatory disorders were not significant. Multimorbidity for acute conditions is observed to be decreasing during the pandemic while multimorbidity for chronic conditions remains unchanged. Our graph analytics framework provides guidelines for empirical analysis of disease multimorbidity using electronic health records. The patterns identified using our proposed graph model informs future research and healthcare policy makers for pre-emptive decision making.
通过识别医院就诊记录中的疾病模式,可以预防COVID-19大流行对卫生保健系统的持久影响。随着人口老龄化和长期疾病变得更加普遍,疾病多发病或多种疾病同时发生是一个日益严峻的全球公共卫生挑战。我们提出了一个图表分析框架,分析疾病的多发病在医院就诊。在这个框架内,我们提出了一个图表模型来解释多重发病率作为患病率、类别和潜在疾病的慢性性质的函数。我们应用我们的模型来检查和比较美国亚利桑那州公立医院在大流行之前和期间的五个六个月期间的多病模式。我们观察到,精神疾病和呼吸疾病的多病率在流行高峰期间分别增加了34.26%和41.04%,而内分泌疾病和循环系统疾病的多病率梯度不显著。据观察,在大流行期间,急性疾病的多重发病率正在下降,而慢性疾病的多重发病率保持不变。我们的图表分析框架为使用电子健康记录对疾病多发病进行实证分析提供了指导方针。使用我们提出的图模型确定的模式为未来的研究和医疗保健政策制定者提供了先发制人的决策。
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引用次数: 0
MediCoSpace: Visual Decision-Support for Doctor-Patient Consultations using Medical Concept Spaces from EHRs MediCoSpace:使用EHR的医学概念空间为医患咨询提供视觉决策支持
IF 2.5 Q2 COMPUTER SCIENCE, INFORMATION SYSTEMS Pub Date : 2022-09-26 DOI: 10.1145/3564275
Sanne van der Linden, R. Sevastjanova, M. Funk, Mennatallah El-Assady
Healthcare systems are under pressure from an aging population, rising costs, and increasingly complex conditions and treatments. Although data are determined to play a bigger role in how doctors diagnose and prescribe treatments, they struggle due to a lack of time and an abundance of structured and unstructured information. To address this challenge, we introduce MediCoSpace, a visual decision-support tool for more efficient doctor-patient consultations. The tool links patient reports to past and present diagnoses, diseases, drugs, and treatments, both for the current patient and other patients in comparable situations. MediCoSpace uses textual medical data, deep-learning supported text analysis and concept spaces to facilitate a visual discovery process. The tool is evaluated by five medical doctors. The results show that MediCoSpace facilitates a promising, yet complex way to discover unlikely relations and thus suggests a path toward the development of interactive visual tools to provide physicians with more holistic diagnoses and personalized, dynamic treatments for patients.
医疗保健系统面临着来自人口老龄化、成本上升以及日益复杂的条件和治疗的压力。尽管数据在医生的诊断和处方治疗中发挥了更大的作用,但由于缺乏时间和丰富的结构化和非结构化信息,他们很难。为了应对这一挑战,我们引入了MediCoSpace,这是一个可视化的决策支持工具,可以提高医患咨询的效率。该工具将患者报告与过去和现在的诊断、疾病、药物和治疗联系起来,既适用于当前患者,也适用于处于类似情况的其他患者。MediCoSpace使用文本医学数据、深度学习支持的文本分析和概念空间来促进视觉发现过程。该工具由五名医生进行评估。结果表明,MediCoSpace促进了一种有前途但复杂的方法来发现不可能的关系,从而为开发交互式可视化工具提供了一条道路,为医生提供更全面的诊断和个性化的动态治疗。
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引用次数: 0
A Human-in-the-Loop Segmented Mixed-Effects Modeling Method for Analyzing Wearables Data 可穿戴设备数据分析的人在环分段混合效应建模方法
IF 2.5 Q2 COMPUTER SCIENCE, INFORMATION SYSTEMS Pub Date : 2022-09-24 DOI: 10.1145/3564276
Karthik Srinivasan, Faiz Currim, S. Ram
Wearables are an important source of big data, as they provide real-time high-resolution data logs of health indicators of individuals. Higher-order associations between pairs of variables is common in wearables data. Representing higher-order association curves as piecewise linear segments in a regression model makes them more interpretable. However, existing methods for identifying the change points for segmented modeling either overfit or have low external validity for wearables data containing repeated measures. Therefore, we propose a human-in-the-loop method for segmented modeling of higher-order pairwise associations between variables in wearables data. Our method uses the smooth function estimated by a generalized additive mixed model to allow the analyst to annotate change point estimates for a segmented mixed-effects model, and thereafter employs Brent's constrained optimization procedure to fine-tune the manually provided estimates. We validate our method using three real-world wearables datasets. Our method not only outperforms state-of-the-art modeling methods in terms of prediction performance but also provides more interpretable results. Our study contributes to health data science in terms of developing a new method for interpretable modeling of wearables data. Our analysis uncovers interesting insights on higher-order associations for health researchers.
可穿戴设备提供个人健康指标的实时高分辨率数据日志,是大数据的重要来源。变量对之间的高阶关联在可穿戴设备数据中很常见。将高阶关联曲线表示为回归模型中的分段线性段,使它们更易于解释。然而,对于包含重复测量的可穿戴设备数据,现有的识别分段建模变化点的方法要么过拟合,要么外部有效性较低。因此,我们提出了一种人在环方法,用于可穿戴设备数据中变量之间高阶成对关联的分段建模。我们的方法使用由广义加性混合模型估计的平滑函数,允许分析人员对分段混合效应模型的变化点估计进行注释,然后使用Brent的约束优化程序对手动提供的估计进行微调。我们使用三个真实的可穿戴设备数据集验证了我们的方法。我们的方法不仅在预测性能方面优于最先进的建模方法,而且还提供了更多可解释的结果。我们的研究为健康数据科学做出了贡献,为可穿戴设备数据的可解释建模开发了一种新方法。我们的分析揭示了健康研究人员对高阶关联的有趣见解。
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引用次数: 3
Near-Infrared Spectroscopy for Bladder Monitoring: A Machine Learning Approach 用于膀胱监测的近红外光谱:一种机器学习方法
IF 2.5 Q2 COMPUTER SCIENCE, INFORMATION SYSTEMS Pub Date : 2022-09-22 DOI: 10.1145/3563779
Pascal Fechner, Fabian König, Wolfgang Kratsch, Jannik Lockl, Maximilian Röglinger
Patients living with neurogenic bladder dysfunction can lose the sensation of their bladder filling. To avoid over-distension of the urinary bladder and prevent long-term damage to the urinary tract, the gold standard treatment is clean intermittent catheterization at predefined time intervals. However, the emptying schedule does not consider actual bladder volume, meaning that catheterization is performed more often than necessary, which can lead to complications such as urinary tract infections. Time-consuming catheterization also interferes with patients' daily routines and, in the case of an empty bladder, uses human and material resources unnecessarily. To enable individually tailored and volume-responsive bladder management, we design a model for the continuous monitoring of bladder volume. During our design science research process, we evaluate the model's applicability and usefulness through interviews with affected patients, prototyping, and application to a real-world in vivo dataset. The developed prototype predicts bladder volume based on relevant sensor data (i.e., near-infrared spectroscopy and acceleration) and the time elapsed since the previous micturition. Our comparison of several supervised state-of-the-art machine and deep learning models reveals that a long short-term memory network architecture achieves a mean absolute error of 116.7 ml that can improve bladder management for patients.
患有神经源性膀胱功能障碍的患者可能会失去膀胱充盈感。为了避免膀胱过度扩张并防止对尿路的长期损害,黄金标准的治疗方法是在预定的时间间隔内进行清洁的间歇性导管插入术。然而,排空时间表没有考虑实际的膀胱容量,这意味着导管插入术的频率超过了必要的频率,这可能会导致并发症,如尿路感染。耗时的导管插入术也会干扰患者的日常生活,在膀胱排空的情况下,会不必要地使用人力和物力。为了实现个性化和容量响应性膀胱管理,我们设计了一个持续监测膀胱容量的模型。在我们的设计科学研究过程中,我们通过采访受影响的患者、原型设计和应用于真实世界的体内数据集来评估该模型的适用性和有用性。开发的原型基于相关传感器数据(即近红外光谱和加速度)和上次排尿后的时间来预测膀胱体积。我们对几种受监督的最先进的机器和深度学习模型的比较表明,长短期记忆网络架构的平均绝对误差为116.7ml,可以改善患者的膀胱管理。
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引用次数: 2
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ACM Transactions on Management Information Systems
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