International Orthodontics最新文献

{"title":"Mandibular molar protraction using round Australian wire and miniscrew anchorage with modified corticision in an adult with first molar loss: A case report","authors":"Qingjuan Shi ,&nbsp;Qinglian Zhang ,&nbsp;Hong Zheng,&nbsp;Yi Wang","doi":"10.1016/j.ortho.2025.101032","DOIUrl":"10.1016/j.ortho.2025.101032","url":null,"abstract":"<div><div>A 27-year-old adult female presented with the chief complaint of bilateral mandibular first molar absence and strongly preferred to use wisdom teeth rather than prosthetic replacements. Treatment was carried out using a round Australian wire fixed orthodontic technique. The second and third molars were mesially moved with a bilateral terminal helical loop combined with curved tip-back bends in Australian wire. Miniscrew anchorage was placed in the mandibular premolar area to assist in the protraction of the second and third molars. Additionally, a modified cortical drilling technique was employed to accelerate tooth movement. A neutral molar relationship was established while maintaining the patient's facial profile.</div></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"23 4","pages":"Article 101032"},"PeriodicalIF":1.8,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144262069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-dimensional assessment of mini-implant supported maxillary canine retraction with and without power arm in class II division 1 patients: A split-mouth randomized trial","authors":"Anas Nedal Kassas,&nbsp;Ahmed Mohamed Kamel,&nbsp;Mohammad Hasan Mohammad,&nbsp;Maher Abd El-Salam Fouda,&nbsp;Mona Abdelaziz Montasser","doi":"10.1016/j.ortho.2025.101030","DOIUrl":"10.1016/j.ortho.2025.101030","url":null,"abstract":"<div><h3>Introduction</h3><div>The primary objectives of this trial were to compare the mechanics of direct sliding (DS) and power arm sliding (PAS) methods for canine retraction in regard to the rate of retraction, rotation, and tipping. The secondary objectives included the evaluation of canine mobility, mini-implant stability, and pain.</div></div><div><h3>Material and methods</h3><div>This split-mouth study was conducted over a 12-month intervention period on young adult patients with Class II Division 1 malocclusion requiring extraction of the maxillary first premolars, recruited between July 2023 and January 2024. Retraction methods were randomly assigned to sides by coin toss. Closed coil springs applying 150<!--> <!-->g retraction forces were stretched to the canine bracket hook on one side and the power arm on the contralateral side. Digital models were analysed to measure canine retraction rate, tipping, and rotation. Canine mobility and mini-implant stability were assessed with the periotest. The pain was evaluated using a visual analogue scale. Data were analysed using two-way mixed ANOVA, and intraclass correlation test. Blinding was only used during data analysis.</div></div><div><h3>Results</h3><div>Twenty patients (aged 18.35<!--> <!-->±<!--> <!-->2.85) were included. The total retraction rate was greater in DS (4.42<!--> <!-->±<!--> <!-->0.75<!--> <!-->mm) compared to PAS (2.93<!--> <!-->±<!--> <!-->0.56<!--> <!-->mm) with <em>P</em> <!-->&lt;<!--> <!-->0.001. Tipping and rotation were significantly higher in DS compared to PAS with <em>P</em> <!-->&lt;<!--> <!-->0.001, <em>P</em> <!-->=<!--> <!-->0.031, respectively. No statistically significant differences were observed between the 2 methods regarding mini-implant stability, and pain. However, canine mobility revealed a significant difference only during the first and second months (<em>P</em> <!-->=<!--> <!-->0.005, P<!--> <!-->=<!--> <!-->0.003, respectively) with higher periotest values recorded in the PAS group. No harm was observed during the trial.</div></div><div><h3>Conclusions</h3><div>The DS method resulted in a faster rate of retraction than the PAS method. However, the PAS method effectively reduced both tipping and rotation, facilitating a more controlled bodily movement during canine retraction.</div><div>Trial registration in Clinical-Trial.gov under identification number <span><span>NCT06352996</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"23 4","pages":"Article 101030"},"PeriodicalIF":1.8,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144168881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orthodontic tooth movement in alveolar bone augmentation area: A systematic review of animal studies","authors":"Si-Min Wang ,&nbsp;Jia He ,&nbsp;Wen-Yu Chuo ,&nbsp;Lin Wu","doi":"10.1016/j.ortho.2025.101031","DOIUrl":"10.1016/j.ortho.2025.101031","url":null,"abstract":"<div><h3>Objectives</h3><div>This systematic review aims to evaluate the optimal timing for orthodontic tooth movement (OTM) following alveolar bone augmentation, the types of alveolar bone graft materials used, and the associated animal models.</div></div><div><h3>Material and methods</h3><div>A systematic search was conducted across PubMed, Web of Science, Cochrane Library, Scopus, and grey literature databases, covering studies from January 1st, 2014, to November 30th, 2024. Studies addressing combined alveolar bone augmentation and OTM were selected, with outcomes such as OTM rate, bone formation, and root resorption assessed through imaging or histological methods. A control group was required in animal experiments. There were no language restrictions. Article screening and data extraction were performed independently by two reviewers. The SYRCLE risk-of-bias tool was used to evaluate study quality.</div></div><div><h3>Results</h3><div>Fourteen animal studies were included, with subjects comprising dogs, rats, mice, and rabbits. The graft materials predominantly consisted of allografts, xenografts, and alloplasts. The applied orthodontic force ranged from 10<!--> <!-->g to 150<!--> <!-->g, with OTM performed at intervals of 0 to 3<!--> <!-->months. Methodologies included model measurements, imaging, and histological analyses.</div></div><div><h3>Conclusion</h3><div>OTM can be performed during the bone weaving stage, however, the use of alveolar bone grafts generally impedes OTM. Alloplasts are associated with less root resorption. Animal models should closely mirror human characteristics, considering factors such as sex, age, defect location and size, type of tooth movement, and force magnitude. Overall, the quality of the studies is suboptimal, and further well-designed animal and human studies are needed.</div><div>This systematic review has been registered with PROSPERO (CRD42025642198).</div></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"23 4","pages":"Article 101031"},"PeriodicalIF":1.8,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144168850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biocompatibility of direct printed clear aligners: A systematic review of in vitro studies","authors":"Claire-Adeline Dantagnan ,&nbsp;Sylvie Babajko ,&nbsp;Ali Nassif ,&nbsp;André Porporatti ,&nbsp;Jean-Pierre Attal ,&nbsp;Elisabeth Dursun ,&nbsp;Jean-François Nguyen ,&nbsp;Julia Bosco","doi":"10.1016/j.ortho.2025.101028","DOIUrl":"10.1016/j.ortho.2025.101028","url":null,"abstract":"<div><h3>Objective</h3><div>Three-dimensional printing of aligners has gained in popularity as an alternative to thermoformed aligners. Only few studies evaluate the biological effects of these new materials. This systematic review aims to investigate the residual monomers leaching from direct printed clear aligners and their possible toxic effects.</div></div><div><h3>Search methods</h3><div>A search was conducted on several databases in accordance with PRISMA guidelines. In vitro, in vivo and clinical studies in English were included. The risk of bias of in vitro studies was assessed by QUIN Tool, for in vivo studies with the SYRCLE tool and for clinical studies with the RoB-2 tool.</div></div><div><h3>Results</h3><div>In all, 524 articles were initially identified and nine were included in the qualitative analysis. All the included studies were in vitro research with a moderate risk of bias. Seven studies were focused on cell toxicity and two on monomer release. Although mixed results are described, 3D printed aligners could present a slight cytotoxicity. Compared with thermoformed aligners, direct printed aligners had higher cytotoxicity levels. No estrogenic effects and no trace of Bisphenol A (BPA) release were detected from printed aligners when investigated but a leaching of Urethane Dimethacrylate (UDMA) have been reported in all studies. Post-curing was an important step to obtain satisfactory biocompatibility of printed aligners.</div></div><div><h3>Conclusions</h3><div>There is no consensus on the absence of cytotoxic effects of direct printed aligners but the release of some potentially active monomers including UDMA requires further investigations on long-term effects on patients’ health.</div></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"23 4","pages":"Article 101028"},"PeriodicalIF":1.8,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144147397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mandibular canal angle, length and curvature in the three facial growth patterns and their association with vertical dysplasia indicators in adult patients: A retrospective cross-sectional 2D cephalometric study","authors":"Madhanraj Selvaraj,&nbsp;Piramanayagam Varshitha,&nbsp;Bhaskar Nivethitha,&nbsp;Balasubramanian Madhan","doi":"10.1016/j.ortho.2025.101026","DOIUrl":"10.1016/j.ortho.2025.101026","url":null,"abstract":"<div><h3>Objective</h3><div>The study compared the cephalometric mandibular canal (MC) morphology in different facial growth patterns and its association with other common vertical dysplasia indicators (VDI).</div></div><div><h3>Material and methods</h3><div>Pretreatment lateral cephalograms of 111 individuals (18–40 years) were categorised as normodivergent (ND), hypodivergent (HypoD), and hyperdivergent (HyperD) growth patterns based on SNGoGn. The mandibular canal angle (MCA) and VDI were estimated using cephalometric software. The mandibular canal length (MCL) and mandibular canal curvature (MCC) were calculated using the B-spline curve fitting method. The statistical analyses included comparing the MC variables across the three growth patterns and assessing their correlations with other VDI. Linear models were used to evaluate the multivariate effects of growth pattern, age and sex on MC variables.</div></div><div><h3>Results</h3><div>The HyperD group showed the highest median MCA (150°) followed by ND (146°) and HypoD (141°), with all intergroup differences significant at <em>P</em> <!-->&lt;<!--> <!-->0.001. There was no statistically significant difference in the MCL between the groups (ND<!--> <!-->=<!--> <!-->57<!--> <!-->±<!--> <!-->4.3, HypoD<!--> <!-->=<!--> <!-->58.2<!--> <!-->±<!--> <!-->4.5, HyperD<!--> <!-->=<!--> <!-->57.9<!--> <!-->±<!--> <!-->5.1<!--> <!-->mm). The MCC radius was higher in HyperD (44.9<!--> <!-->±<!--> <!-->8.7<!--> <!-->mm) than in ND (39.1<!--> <!-->±<!--> <!-->11.7, <em>P</em> <!-->=<!--> <!-->0.034) and HypoD group (38.7<!--> <!-->±<!--> <!-->8.5<!--> <!-->mm, <em>P</em> <!-->=<!--> <!-->0.026), implying a less curved MC in HyperD group. The age and sex of the individual did not have any significant impact on the MC variables. While MCA demonstrated moderate to high correlation with many VDI, the other two were not correlated with most.</div></div><div><h3>Conclusion</h3><div>The mandibular canal angle and curvature are potential cephalometric indicators of facial growth patterns, with the former being more robust and practical for routine clinical applications.</div></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"23 4","pages":"Article 101026"},"PeriodicalIF":1.8,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144115304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retention of pubertal cervical vertebral maturation stages in adults (20–45 years). Limitations of cervical vertebral maturation in growth status assessment: A cross-sectional study","authors":"Erum Amin ,&nbsp;Sajid Ali ,&nbsp;Rana Faiza ,&nbsp;Marium Jamil ,&nbsp;Qasim Khalid ,&nbsp;Umar Hussain ,&nbsp;Nikoloas Pandis","doi":"10.1016/j.ortho.2025.101027","DOIUrl":"10.1016/j.ortho.2025.101027","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the retention of pubertal cervical vertebral maturation (CVM) stages in adults and assess the association of vertical and sagittal skeletal patterns on this retention.</div></div><div><h3>Methods</h3><div>This cross-sectional study was conducted on pre-treatment records of 489 adult participants (286 females and 203 males) aged 20 to 45. Inclusion criteria were clear lateral cephalometric radiographs and the absence of systemic conditions or previous orthodontic treatment affecting skeletal maturation. Skeletal sagittal and vertical patterns were recorded. Associations between CVM stages and sex, skeletal sagittal, and vertical pattern were analysed using inverse probability weighting (IPW)-adjusted ordinal logistic regression for age.</div></div><div><h3>Results</h3><div>The mean age was 26.09 (4.84) years. CS4 was retained in 8.59% and CS5 in 19.63%. Age varied significantly across stages (<em>P</em> <!-->=<!--> <!-->0.01) with participants in CS5 being older. A significant sex difference was observed (<em>P</em> <!-->=<!--> <!-->0.01) with more males in CS6 and more females in CS5. Skeletal class was significantly associated with CVM stages (<em>P</em> <!-->=<!--> <!-->0.001) with Class III subjects more likely to exhibit less mature CVM stages. However, the vertical pattern was not significantly associated with CVM stages (<em>P</em> <!-->=<!--> <!-->0.63). Ordinal logistic regression showed that Class III participants had a significantly lower likelihood of attaining CS6 (OR<!--> <!-->=<!--> <!-->0.30, 95% CI: 0.16–0.54, <em>P</em> <!-->&lt;<!--> <!-->0.001) while vertical pattern and sex were not significant predictors after age adjustment.</div></div><div><h3>Conclusion</h3><div>A higher proportion of adults did not attain the post-pubertal CVM stage, especially in Class III malocclusion, raising concerns about CVM's reliability. Multiple growth indicators in combination with physical appearance should be used for skeletal maturation assessment.</div></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"23 4","pages":"Article 101027"},"PeriodicalIF":1.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144089196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of propolis, fluoride and probiotic mouthwashes on streptococcus mutans and oxidative stress in fixed orthodontic patients: A triple-blind, randomized controlled trial with 9-month follow-up","authors":"Praveen Chandrashekaraiah ,&nbsp;Reshma Benzigar ,&nbsp;Ramya Shivananjan ,&nbsp;Selva Arockiam ,&nbsp;Nithya Nandhini ,&nbsp;Sangeetha Ulaganathan","doi":"10.1016/j.ortho.2025.101017","DOIUrl":"10.1016/j.ortho.2025.101017","url":null,"abstract":"<div><h3>Background</h3><div>Fixed orthodontic appliances increase the risk of enamel demineralization due to plaque accumulation. While fluoride mouthwash is well established, propolis and probiotic formulations are emerging alternatives with antimicrobial and anti-inflammatory potential.</div></div><div><h3>Aim</h3><div>To compare the effects of propolis, fluoride, and probiotic mouthwashes on <em>Streptococcus mutans</em> levels and oxidative stress (8-OHdG) in patients undergoing fixed orthodontic treatment.</div></div><div><h3>Materials and methods</h3><div>Of 120 patients screened (March 2022–February 2023), 90 were randomized into three groups (<em>n</em> <!-->=<!--> <!-->30 each): propolis, fluoride, and probiotic. <em>S.</em> <em>mutans</em> was quantified at baseline, 30 days, 3-, 6- and 9-months using Q-PCR. Salivary 8-OHdG was measured using ELISA. Dietary and oral hygiene behaviours were monitored through a mobile app, interviews and 24-hour dietary recalls.</div></div><div><h3>Results</h3><div><em>S.</em> <em>mutans</em> levels (log10 CFU/mL) significantly decreased (<em>P</em> <!-->&lt;<!--> <!-->0.001) at 9 months: from 4.35<!--> <!-->±<!--> <!-->0.45 to 0.89<!--> <!-->±<!--> <!-->0.06 (propolis), 4.42<!--> <!-->±<!--> <!-->0.49 to 2.74<!--> <!-->±<!--> <!-->0.18 (fluoride), and 4.38<!--> <!-->±<!--> <!-->0.50 to 3.21<!--> <!-->±<!--> <!-->0.06 (probiotic). Ct values increased accordingly, confirming reduced bacterial load. Salivary 8-OHdG (ng/mL) declined significantly (<em>P</em> <!-->&lt;<!--> <!-->0.001): 3.8<!--> <!-->±<!--> <!-->0.8 to 0.32<!--> <!-->±<!--> <!-->0.14 (propolis), 3.9<!--> <!-->±<!--> <!-->0.7 to 1.32<!--> <!-->±<!--> <!-->0.18 (fluoride), 3.8<!--> <!-->±<!--> <!-->0.6 to 2.42<!--> <!-->±<!--> <!-->0.22 (probiotic).</div></div><div><h3>Conclusion</h3><div>Propolis mouthwash produced the greatest reductions likely due to the combined effect of standardized extract and essential oils added for taste. Fluoride remained effective for microbial control, while probiotics offered modest benefit. High compliance strengthened these findings. Further studies should isolate active components and assess long-term effects in broader settings.</div></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"23 4","pages":"Article 101017"},"PeriodicalIF":1.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144068013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of combining intraoral and facial scan in a single digital model of an orthodontic patient utilizing corresponding measurements on the model and on real photographs: A prospective cross-sectional study","authors":"Michail Vasoglou ,&nbsp;Ioanna Pouliezou ,&nbsp;Konstantinos Apostolopoulos ,&nbsp;Georgios Vasoglou","doi":"10.1016/j.ortho.2025.101015","DOIUrl":"10.1016/j.ortho.2025.101015","url":null,"abstract":"<div><h3>Objectives</h3><div>To validate the accuracy of integration of intraoral scan to the facial scan acquired by the EM3D application, utilising the Blue Sky Plan 4 software, creating a digital model of an orthodontic patient, by comparing the same linear measurements on real photographs and images from the digital model of the patient.</div></div><div><h3>Material and methods</h3><div>Thirty patients (20 females and 10 males; age range 12–30<!--> <!-->years) undergoing orthodontic treatment with fixed appliances were recruited in this prospective cross-sectional study from December 2024 to February 2025. Five facial landmarks were marked on each patient: Tragion right, Cheilion right and left, Subnasale and Pronasale. Intraoral scan and facial scan were performed at the same appointment. Facial scan was conducted using an iPhone 13 Pro with the EM3D face scanning application which utilizes the iPhone's TrueDepth camera technology while the patient was smiling. The STL (Stereolithography) and OBG (Object) files (acquired from intraoral and facial scan respectively) were combined in a digital model using the Blue Sky Plan 4 software. Lateral and frontal photographs of the patient's face, while smiling, were also acquired. Eight linear measurements (Tragion right – bracket #11, Tragion right – incisal #11, Cheilion right – #13, Cheilion left – #13, Subnasale – #11, Subnasale – #21, Pronasale – #11, Pronasale – #21) were digitally performed on the real and digital photographs of the patients using the facial landmarks and certain points on teeth and braces. Paired sample <em>t</em>-test and Wilcoxon signed-rank test were used for statistical analysis.</div></div><div><h3>Results</h3><div>Significantly statistical difference was detected only in one (Cheilion right – #13) measurement (<em>P</em> <!-->=<!--> <!-->0.004).</div></div><div><h3>Conclusion</h3><div>Combining intraoral and facial scan using a special software provides a clinically useful digital model of an orthodontic patient for diagnosis, treatment planning and outcome assessment.</div></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"23 4","pages":"Article 101015"},"PeriodicalIF":1.8,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143922787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knoop microhardness, surface roughness, and cytotoxicity analysis of arginine-modified experimental orthodontic resins: An in vitro study","authors":"Pérola Costa Bitencourt Santos ,&nbsp;Analia Gabriella Borges Ferraz Facury ,&nbsp;Lenita Marangoni Lopes ,&nbsp;Mário Alexandre Coelho Sinhoreti ,&nbsp;Daniel Navarro da Rocha ,&nbsp;Lourenço Correr-Sobrinho ,&nbsp;Ana Rosa Costa ,&nbsp;José Guilherme Neves","doi":"10.1016/j.ortho.2025.101014","DOIUrl":"10.1016/j.ortho.2025.101014","url":null,"abstract":"<div><h3>Aim</h3><div>The study aimed to evaluate the impact of incorporating 2.5%, 5%, and 7% arginine on the hardness, roughness, and cytotoxicity of 3M™ Transbond™ XT.</div></div><div><h3>Material and methods</h3><div>A total of 48 samples were divided into four groups (<em>n</em> <!-->=<!--> <!-->12): G1 – commercial resin 3M™ Transbond™ XT (TXT); G2 – TXT<!--> <!-->+<!--> <!-->2.5% arginine; G3 – TXT<!--> <!-->+<!--> <!-->5% arginine; and G4 – TXT<!--> <!-->+<!--> <!-->7% arginine. The hardness analysis was performed by a microhardness tester. The measurements of roughness were performed by a surface roughness measuring instrument. The surface morphology analysis was analyzed by digital images obtained with a scanning electron microscope (SEM). For the in vitro cytotoxicity test, dental pulp mesenchymal cells underwent a cell viability reduction assay. For statistical analysis, ANOVA (one-way/two-way) was used, followed by Tukey's test post hoc (<em>P</em> <!-->&lt;<!--> <!-->0.05).</div></div><div><h3>Results</h3><div>There was a reduction in the hardness of experimental resins compared to 3M™ Transbond™ XT commercial resin (<em>P</em> &lt; 0.05). There was no difference between concentrations of 2.5% and 5%, but there was the largest reduction in resin with 7% arginine (<em>P</em> &lt; 0.05). Surface roughness analysis showed there was no statistical difference between the samples (P ≥ 0.05). SEM also did not demonstrate changes in the surface roughness of the resins. All groups exhibited good cell viability at each timepoint. After 48h, an increase was observed for groups contaning arginine <!--> <!--> <!--> (<em>P</em> &lt; 0.05).<strong><em>Conclusion:</em></strong> Surface hardness was modified with when arginine incorporation - to the Transbond™ XT resin formulation. No differences were observed for surface roughness. Due to the initial cytotoxicity of the resins, precautions regarding satisfactory photopolymerization and the distance of application in relation to the gingival tissues must be adopted.</div></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"23 4","pages":"Article 101014"},"PeriodicalIF":1.8,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143922786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment for adult female temporomandibular joint osteoarthritis-related severe retrognathia and anterior open bite using premolar extraction and customized lingual orthodontic appliance with vertical control for significant compensation: A case report","authors":"Qiang Zhou ,&nbsp;Yue Zhang ,&nbsp;Jin Ke ,&nbsp;Yingjie Li","doi":"10.1016/j.ortho.2025.101016","DOIUrl":"10.1016/j.ortho.2025.101016","url":null,"abstract":"<div><div>This case report presents a satisfactory lingual appliance orthodontic treatment in a 21-year-old woman diagnosed with Angle Class I anterior open bite (AOB) malocclusion and severe high-angle skeletal Class II retrognathia, which was attributed to bilateral temporomandibular osteoarthritis (TMJOA) and disc perforation. Because of the absence of joint symptoms and presence of bilateral condyles in a stable state, no conservative or surgical treatments were performed for this patient. Four first premolars and four third molars were extracted before bonding of the customized lingual brackets. No miniscrews were used during the orthodontic process. Space closure was performed using the double cable method. Finally, the maxillary molars were found to have intruded and moved mesially during the space-closing process, which resulted in a 2.9° decrease in the mandibular plane angle. Owing to the counter-clockwise rotation of the mandible, the chin moved anteriorly and superiorly. In addition, the anterior teeth were largely retracted because of the advantage of this customized lingual appliance, resulting in significant changes in the nasolabial angle and chin contour. Two-year follow-up examinations further confirmed that no obvious relapse in occlusion and no further condylar resorption, even though bilateral anterior disc displacement without reduction was revealed. In conclusion, a patient with TMJOA-related severe chin retrognathia and AOB treated with a lingual appliance showed satisfactory improvement in facial profile and occlusion.</div></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"23 4","pages":"Article 101016"},"PeriodicalIF":1.8,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143906412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}