Pub Date : 2024-02-22DOI: 10.1016/j.ortho.2024.100850
Navraj Mattu , Aravind M. Virupaksha , Anup Belludi
{"title":"Corrigendum to “Comparative study of effect of different lever arm positions and lengths on transverse and vertical bowing in lingual orthodontics - An FEM study” [International Orthodontics 2021;19: 281–290]","authors":"Navraj Mattu , Aravind M. Virupaksha , Anup Belludi","doi":"10.1016/j.ortho.2024.100850","DOIUrl":"https://doi.org/10.1016/j.ortho.2024.100850","url":null,"abstract":"","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"22 2","pages":"Article 100850"},"PeriodicalIF":1.5,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1761722724000068/pdfft?md5=20f7932b0dad4969458595a248e04ac0&pid=1-s2.0-S1761722724000068-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139936754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-19DOI: 10.1016/j.ortho.2024.100848
Enrico Albertini, Paolo Albertini, Anna Colonna, Luca Lombardo
This case report describes a complex full-step class II case in a young adult patient treated with lingual straight-wire appliance and upper first molar extraction. As the patient refused a surgical treatment, she was offered the best possible camouflage with the double aim of obtaining an ideal occlusal relationship and maintaining the profile; appropriate biomechanical strategies, including extraction choice and anchorage control during space closure, were needed to achieve the planned results. This case report demonstrates the possibility of successfully resolving severe sagittal discrepancies in an adult patient without surgical treatment by means of a completely invisible non-compliance technique, with the extraction of the most compromised teeth. This report also underlines the need for careful planning during both diagnostic and treatment phases, in order to obtain the best results.
本病例报告描述了一名年轻成人患者的复杂全阶梯 II 类病例,患者使用舌侧直丝矫治器和上第一磨牙拔除术进行治疗。由于患者拒绝手术治疗,我们为她提供了尽可能好的伪装,以达到获得理想咬合关系和保持外形的双重目的;为了达到计划的效果,需要采取适当的生物力学策略,包括拔牙选择和间隙关闭时的锚定控制。本病例报告展示了通过完全隐形的非依从技术,在不进行外科手术治疗的情况下,拔除受损最严重的牙齿,成功解决成年患者严重矢状不齐问题的可能性。该报告还强调了在诊断和治疗阶段进行仔细规划的必要性,以便获得最佳效果。
{"title":"Non-compliance treatment in a young adult full-step class II division 2 malocclusion with preadjusted lingual appliance and upper first molars extractions","authors":"Enrico Albertini, Paolo Albertini, Anna Colonna, Luca Lombardo","doi":"10.1016/j.ortho.2024.100848","DOIUrl":"https://doi.org/10.1016/j.ortho.2024.100848","url":null,"abstract":"<div><p>This case report describes a complex full-step class II case in a young adult patient treated with lingual straight-wire appliance and upper first molar extraction. As the patient refused a surgical treatment, she was offered the best possible camouflage with the double aim of obtaining an ideal occlusal relationship and maintaining the profile; appropriate biomechanical strategies, including extraction choice and anchorage control during space closure, were needed to achieve the planned results. This case report demonstrates the possibility of successfully resolving severe sagittal discrepancies in an adult patient without surgical treatment by means of a completely invisible non-compliance technique, with the extraction of the most compromised teeth. This report also underlines the need for careful planning during both diagnostic and treatment phases, in order to obtain the best results.</p></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"22 2","pages":"Article 100848"},"PeriodicalIF":1.5,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139901412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-12DOI: 10.1016/j.ortho.2024.100845
Marco Farronato , Niccolò Cenzato , Roberta Crispino , Francesco Carlo Tartaglia , Roberto Biagi , Benedetta Baldini , Cinzia Maspero
Background
Facial soft tissue analysis is becoming increasingly emphasized in orthodontic diagnosis and treatment planning. While traditional cephalometry primarily focuses on hard tissues, recent non-invasive imaging techniques offer the potential to comprehensively evaluate three-dimensional (3D) facial soft tissues. The aim of the study was to establish the geometrical 3D and cephalometric divergence between Cone Beam Computed Tomography (CBCT) derived images and scanned soft tissues. Crucial for enhancing orthodontic diagnosis, minimizing patient exposure to ionizing radiation and providing facial cephalometric parameters.
Material and methods
A cross-sectional study was conducted from January 2020 to May 2023. CBCT and 3D facial scans were obtained simultaneously using a specialized imaging system. Reproducible landmark points were selected for both cephalometric and soft tissue analysis. Angular and linear measurements were recorded, and correlations between CT and facial scans were statistically assessed.
Results
Comparisons between 10 CBCT-derived and 10 facial scan-based soft tissue representations resulted into 1.8 mm mean root median square (RMS). Angular measurements, such as ANB, right gonial angle, and left gonial angle, exhibited a 0.9° of difference with their respective soft tissue variables. In contrast, linear measurements of total anterior facial height showed a lower correlation coefficient, equal to 0.51. The correlation between soft tissues and underlying hard tissues was more pronounced for gonial angles.
Conclusion
Facial soft tissue analysis using either 3D facial scans or CBCT-derived offers similar results for orthodontic diagnosis and treatment planning. These findings support the use of non-invasive diagnostic tools in orthodontics, although further investigations are needed to comprehensively understand the complexity of hard and soft tissue relationships.
{"title":"Divergence between CBCT and Optical Scans for Soft Tissue Analysis and Cephalometry in Facial Imaging: A cross-sectional study on healthy adults","authors":"Marco Farronato , Niccolò Cenzato , Roberta Crispino , Francesco Carlo Tartaglia , Roberto Biagi , Benedetta Baldini , Cinzia Maspero","doi":"10.1016/j.ortho.2024.100845","DOIUrl":"https://doi.org/10.1016/j.ortho.2024.100845","url":null,"abstract":"<div><h3>Background</h3><p>Facial soft tissue analysis is becoming increasingly emphasized in orthodontic diagnosis and treatment planning. While traditional cephalometry primarily focuses on hard tissues, recent non-invasive imaging techniques offer the potential to comprehensively evaluate three-dimensional (3D) facial soft tissues. The aim of the study was to establish the geometrical 3D and cephalometric divergence between Cone Beam Computed Tomography (CBCT) derived images and scanned soft tissues. Crucial for enhancing orthodontic diagnosis, minimizing patient exposure to ionizing radiation and providing facial cephalometric parameters.</p></div><div><h3>Material and methods</h3><p>A cross-sectional study was conducted from January 2020 to May 2023. CBCT and 3D facial scans were obtained simultaneously using a specialized imaging system. Reproducible landmark points were selected for both cephalometric and soft tissue analysis. Angular and linear measurements were recorded, and correlations between CT and facial scans were statistically assessed.</p></div><div><h3>Results</h3><p>Comparisons between 10 CBCT-derived and 10 facial scan-based soft tissue representations resulted into 1.8<!--> <!-->mm mean root median square (RMS). Angular measurements, such as ANB, right gonial angle, and left gonial angle, exhibited a 0.9° of difference with their respective soft tissue variables. In contrast, linear measurements of total anterior facial height showed a lower correlation coefficient, equal to 0.51. The correlation between soft tissues and underlying hard tissues was more pronounced for gonial angles.</p></div><div><h3>Conclusion</h3><p>Facial soft tissue analysis using either 3D facial scans or CBCT-derived offers similar results for orthodontic diagnosis and treatment planning. These findings support the use of non-invasive diagnostic tools in orthodontics, although further investigations are needed to comprehensively understand the complexity of hard and soft tissue relationships.</p></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"22 2","pages":"Article 100845"},"PeriodicalIF":1.5,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1761722724000020/pdfft?md5=a0a048c773b54f3a3efa34846be3ae32&pid=1-s2.0-S1761722724000020-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139719520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to evaluate how the addition of resveratrol nanoparticles (RNPs), which act as an antimicrobial agent, affects the strength of acrylic resin used in orthodontics.
Methods
According to ISO 20795-1-2013, 76 cold cure acrylic resin samples (65 × 10 × 3.3 mm) were prepared. The samples were divided into four groups (19 samples in each group) based on RN concentrations added to 1 mL acrylic monomer (0 for control, 256, 512, and 1024 μg/mL). Flexural strength was assessed in megapascal (MPa) using a universal testing machine. Data analysis involved nonparametric Kruskal-Wallis analysis of variance and pairwise post-hoc Dunn's test.
Results
The flexural strength decreased as the concentration of RNPs increased, with the lowest value observed at 1024 μg/mL (63.06 ± 5.33 MPa). The control group exhibited the highest mean of flexural strength (88.43 ± 4.41 MPa), followed by the groups with RNPs at the concentrations of 256 μg/mL (82.69 ± 4.41 MPa) and 512 μg/mL (76.02 ± 4.59 MPa).
Conclusion
In conclusion, the addition of RNs to orthodontic acrylic resin had a dose-dependent impact on its flexural strength. Based on the findings, we recommend incorporating RNs at a concentration of 256 μg/mL as an antimicrobial agent in orthodontic acrylic resin. However, further research is necessary to assess the long-term effects and clinical applications of this approach.
{"title":"The flexural strength of orthodontic acrylic resin containing resveratrol nanoparticles as antimicrobial agent: An in vitro study","authors":"Rashin Bahrami , Fateme Gharibpour , Maryam Pourhajibagher , Abbas Bahador","doi":"10.1016/j.ortho.2024.100846","DOIUrl":"https://doi.org/10.1016/j.ortho.2024.100846","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to evaluate how the addition of resveratrol nanoparticles (RNPs), which act as an antimicrobial agent, affects the strength of acrylic resin used in orthodontics.</p></div><div><h3>Methods</h3><p>According to ISO 20795-1-2013, 76 cold cure acrylic resin samples (65<!--> <!-->×<!--> <!-->10<!--> <!-->×<!--> <!-->3.3<!--> <!-->mm) were prepared. The samples were divided into four groups (19 samples in each group) based on RN concentrations added to 1<!--> <!-->mL acrylic monomer (0 for control, 256, 512, and 1024<!--> <!-->μg/mL). Flexural strength was assessed in megapascal (MPa) using a universal testing machine. Data analysis involved nonparametric Kruskal-Wallis analysis of variance and pairwise post-hoc Dunn's test.</p></div><div><h3>Results</h3><p>The flexural strength decreased as the concentration of RNPs increased, with the lowest value observed at 1024<!--> <!-->μg/mL (63.06<!--> <!-->±<!--> <!-->5.33<!--> <!-->MPa). The control group exhibited the highest mean of flexural strength (88.43<!--> <!-->±<!--> <!-->4.41<!--> <!-->MPa), followed by the groups with RNPs at the concentrations of 256<!--> <!-->μg/mL (82.69<!--> <!-->±<!--> <!-->4.41<!--> <!-->MPa) and 512<!--> <!-->μg/mL (76.02<!--> <!-->±<!--> <!-->4.59<!--> <!-->MPa).</p></div><div><h3>Conclusion</h3><p>In conclusion, the addition of RNs to orthodontic acrylic resin had a dose-dependent impact on its flexural strength. Based on the findings, we recommend incorporating RNs at a concentration of 256<!--> <!-->μg/mL as an antimicrobial agent in orthodontic acrylic resin. However, further research is necessary to assess the long-term effects and clinical applications of this approach.</p></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"22 2","pages":"Article 100846"},"PeriodicalIF":1.5,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139714848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-29DOI: 10.1016/j.ortho.2023.100838
Diego Coelho Lorenzoni , Olívia Thomaz de Almeida Monteiro Barbosa, Adriana de Alcantara Cury-Saramago, Cláudia Trindade Mattos
Non-surgical treatment of Class II subdivision may involve complex mechanics or asymmetric tooth extraction in its resolution. This report demonstrates the result and the short-term stability of Class II subdivision treated with asymmetrically installed Herbst appliance followed by conventional fixed orthodontic appliance. The approach allowed the correction of the unilateral Class II molar relationship and increased overjet, as well as the deviation of dental midlines, with improvement in lip posture and facial profile. The results remained stable two years after treatment, confirming the treatment success.
非手术治疗 II 类牙列不齐可能涉及复杂的力学或不对称拔牙。本报告展示了使用不对称安装的赫氏矫治器和传统固定矫治器治疗 II 类牙列不齐的效果和短期稳定性。这种方法可以矫正单侧 II 类臼齿关系和增加的过咬合,以及牙齿中线的偏差,改善唇姿和面部轮廓。治疗两年后,效果保持稳定,证实了治疗的成功。
{"title":"Class II subdivision treatment and stability with asymmetric Herbst appliance: A case report","authors":"Diego Coelho Lorenzoni , Olívia Thomaz de Almeida Monteiro Barbosa, Adriana de Alcantara Cury-Saramago, Cláudia Trindade Mattos","doi":"10.1016/j.ortho.2023.100838","DOIUrl":"10.1016/j.ortho.2023.100838","url":null,"abstract":"<div><p><span><span><span>Non-surgical treatment of Class II subdivision may involve complex mechanics or asymmetric tooth extraction in its resolution. This report demonstrates the result and the short-term stability of Class II subdivision treated with asymmetrically installed </span>Herbst appliance followed by conventional fixed </span>orthodontic appliance. The approach allowed the correction of the unilateral Class II molar relationship and increased </span>overjet, as well as the deviation of dental midlines, with improvement in lip posture and facial profile. The results remained stable two years after treatment, confirming the treatment success.</p></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"22 2","pages":"Article 100838"},"PeriodicalIF":1.5,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139643059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-19DOI: 10.1016/j.ortho.2023.100843
Julian Woolley , Natasha Wright , Maurice J. Meade
Introduction
Detailed insight regarding the use of temporary anchorage devices (TAD) in Australia and the United Kingdom (UK) is lacking. The primary aim of the present cross-sectional survey was to investigate TAD usage among UK-based and Australian-based orthodontists. The secondary objectives were to compare TAD-related preferences and protocols between orthodontists in the two countries.
Methods
A pilot-tested electronic questionnaire was distributed to members of the British Orthodontic Society and the Australian Society of Orthodontists. Questions pertained to their demographic details, and current use of TADs including protocols, treatment objectives and factors influencing their use.
Results
A total of 192 responses were recorded (Australia: 122; UK: 70). One hundred and forty-two respondents (74.0%) reported using TADs as part of their orthodontic treatment, 77.0% in Australia (n = 94) and 68.6% in the UK (n = 48). Molar protraction was the most common procedure for which TADs were reportedly used (Australia: n = 118; 87.2%, UK: n = 36; 75.0%). “Loosening” was the most prevalent reported complication overall (n = 124; 90.1%). “Confidence”, “insufficient postgraduate education” and “availability of equipment” were the factors that most influenced the decision not to provide TADs.
Conclusions
Most orthodontists in both countries provided TADs. TAD protocols of orthodontists in both countries were reported. Similarities and differences regarding TAD-related clinical practices and procedures, complications and factors influencing the use of TADs and reasons for not using TADs were explored. Information from the present study can provide baseline data for future related studies in each country and for comparison of TAD usage in other countries.
导言:关于澳大利亚和英国临时固定装置(TAD)的使用情况还缺乏详细的了解。本次横断面调查的主要目的是调查英国和澳大利亚正畸医师的 TAD 使用情况。方法:向英国正畸学会和澳大利亚正畸学会的会员发放了一份经过试验测试的电子问卷。问题涉及他们的人口统计学细节、目前对 TAD 的使用情况,包括治疗方案、治疗目标和影响其使用的因素。结果 共收到 192 份回复(澳大利亚:122 份;英国:70 份)。142名受访者(74.0%)称使用TADs作为正畸治疗的一部分,其中澳大利亚为77.0%(n=94),英国为68.6%(n=48)。据报告,臼齿牵引是使用 TADs 的最常见程序(澳大利亚:n = 118;87.2%;英国:n = 36;75.0%)。"松动 "是最常见的并发症(124 人;90.1%)。"信心"、"研究生教育不足 "和 "设备可用性 "是影响不提供 TAD 的最大因素。两国正畸医生的 TAD 协议均有报道。研究探讨了与 TAD 相关的临床实践和程序、并发症、影响使用 TAD 的因素以及不使用 TAD 的原因等方面的异同。本研究提供的信息可为两国今后的相关研究提供基线数据,也可用于比较其他国家的 TAD 使用情况。
{"title":"Usage of temporary anchorage devices: A cross-cultural and cross-sectional survey of orthodontists in Australia and the UK","authors":"Julian Woolley , Natasha Wright , Maurice J. Meade","doi":"10.1016/j.ortho.2023.100843","DOIUrl":"https://doi.org/10.1016/j.ortho.2023.100843","url":null,"abstract":"<div><h3>Introduction</h3><p>Detailed insight regarding the use of temporary anchorage devices (TAD) in Australia and the United Kingdom (UK) is lacking. The primary aim of the present cross-sectional survey was to investigate TAD usage among UK-based and Australian-based orthodontists. The secondary objectives were to compare TAD-related preferences and protocols between orthodontists in the two countries.</p></div><div><h3>Methods</h3><p>A pilot-tested electronic questionnaire was distributed to members of the British Orthodontic<span> Society and the Australian Society of Orthodontists. Questions pertained to their demographic details, and current use of TADs including protocols, treatment objectives and factors influencing their use.</span></p></div><div><h3>Results</h3><p><span>A total of 192 responses were recorded (Australia: 122; UK: 70). One hundred and forty-two respondents (74.0%) reported using TADs as part of their orthodontic treatment, 77.0% in Australia (</span><em>n</em> <!-->=<!--> <!-->94) and 68.6% in the UK (<em>n</em> <!-->=<!--> <!-->48). Molar protraction was the most common procedure for which TADs were reportedly used (Australia: <em>n</em> <!-->=<!--> <!-->118; 87.2%, UK: <em>n</em> <!-->=<!--> <!-->36; 75.0%). “Loosening” was the most prevalent reported complication overall (<em>n</em> <!-->=<!--> <!-->124; 90.1%). “Confidence”, “insufficient postgraduate education” and “availability of equipment” were the factors that most influenced the decision not to provide TADs.</p></div><div><h3>Conclusions</h3><p>Most orthodontists in both countries provided TADs. TAD protocols of orthodontists in both countries were reported. Similarities and differences regarding TAD-related clinical practices and procedures, complications and factors influencing the use of TADs and reasons for not using TADs were explored. Information from the present study can provide baseline data for future related studies in each country and for comparison of TAD usage in other countries.</p></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"22 2","pages":"Article 100843"},"PeriodicalIF":1.5,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139503923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-18DOI: 10.1016/j.ortho.2023.100839
Julien Bord
Date of birth
24/09/1998; sex: female.
Pre-treatment documents
13 years 5 months old; 07/03/2012.
Diagnosis
Skeletal Class I with biretrusion, hypodivergent facial pattern; angle's Class II division 1 with overbite; moderate dento-maxillary discrepancy; maxillary incisor malposition.
Treatment planning
Bimaxillary buccal fixed appliance with Class II elastics. Active treatment duration: 25 months.
{"title":"Thirteen-year-old female patient with Class II division 1 malocclusion and hypodivergent facial pattern treated with buccal fixed appliance. Case report no 230052. European College of Orthodontics. Commission of affiliation and titularisation","authors":"Julien Bord","doi":"10.1016/j.ortho.2023.100839","DOIUrl":"https://doi.org/10.1016/j.ortho.2023.100839","url":null,"abstract":"<div><h3>Date of birth</h3><p>24/09/1998; sex: female.</p></div><div><h3>Pre-treatment documents</h3><p>13 years 5 months old; 07/03/2012.</p></div><div><h3>Diagnosis</h3><p>Skeletal Class I with biretrusion, hypodivergent facial pattern; angle's Class II division 1 with overbite<span>; moderate dento-maxillary discrepancy; maxillary incisor malposition.</span></p></div><div><h3>Treatment planning</h3><p>Bimaxillary buccal fixed appliance with Class II elastics. Active treatment duration: 25 months.</p></div><div><h3>Post-treatment documents</h3><p>15 years 7 months old; 09/05/2014.</p></div><div><h3>Post-retention documents</h3><p>(minimum 1 year) 16 years 9 months old; 08/07/2015. Retention period: unlimited.</p></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"22 2","pages":"Article 100839"},"PeriodicalIF":1.5,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139493247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-12DOI: 10.1016/j.ortho.2023.100842
Monika A. Hersberger-Zurfluh , Melih Motro , Alpdogan Kantarci , Leslie A. Will , Theodore Eliades , Spyridon N. Papageorgiou
Introduction
This study aimed to discover the genetic and environmental factors that contribute to the mandibular development of untreated monozygotic and dizygotic twins.
Material and methods
The sample, taken from the Forsyth Moorrees Twin Study, included 52 untreated monozygotic twins (36 male, 16 female) and 46 untreated dizygotic twins (23 male, 23 female). At the ages of 12 and 17, lateral cephalograms were collected and traced to assess total mandibular length, mandibular ramus length, mandibular corpus length, gonial angle, SNB, and bony chin prominence. The genetic and environmental components of variation were assessed using multilevel mixed-effects structural equation modelling.
Results
At 12 years of age, high additive genetic influences were observed for total mandibular length (74%), gonial angle (76%), SNB (41%), and bony chin prominence (64%), whereas strong dominant genetic components were observed for corpus length (72%), and mandibular ramus length was under unique environment influence (54%). At 17 years of age, only total mandibular length (45%), ramus length (53%), gonial angle (76%), and bony chin prominence (68%) were under strong additive genetic control, while the remainder were under strong dominant genetic control.
Conclusions
Although monozygotic and dizygotic twins share at least a portion of their DNA, additive, dominant, or environmental components were discovered during adolescence. Nonetheless, by the age of 17, the majority of the mandibular traits are under either additive or dominant genetic impact.
{"title":"Genetic and environmental impact on mandibular growth in mono- and dizygotic twins during adolescence: A retrospective cohort study","authors":"Monika A. Hersberger-Zurfluh , Melih Motro , Alpdogan Kantarci , Leslie A. Will , Theodore Eliades , Spyridon N. Papageorgiou","doi":"10.1016/j.ortho.2023.100842","DOIUrl":"https://doi.org/10.1016/j.ortho.2023.100842","url":null,"abstract":"<div><h3>Introduction</h3><p>This study aimed to discover the genetic and environmental factors that contribute to the mandibular development of untreated monozygotic and dizygotic twins.</p></div><div><h3>Material and methods</h3><p>The sample, taken from the Forsyth Moorrees Twin Study, included 52 untreated monozygotic twins (36 male, 16 female) and 46 untreated dizygotic twins (23 male, 23 female). At the ages of 12 and 17, lateral cephalograms were collected and traced to assess total mandibular length, mandibular ramus length, mandibular corpus length, gonial angle, SNB, and bony chin prominence. The genetic and environmental components of variation were assessed using multilevel mixed-effects structural equation modelling.</p></div><div><h3>Results</h3><p>At 12 years of age, high additive genetic influences were observed for total mandibular length (74%), gonial angle (76%), SNB (41%), and bony chin prominence (64%), whereas strong dominant genetic components were observed for corpus length (72%), and mandibular ramus length was under unique environment influence (54%). At 17 years of age, only total mandibular length (45%), ramus length (53%), gonial angle (76%), and bony chin prominence (68%) were under strong additive genetic control, while the remainder were under strong dominant genetic control.</p></div><div><h3>Conclusions</h3><p>Although monozygotic and dizygotic twins share at least a portion of their DNA, additive, dominant, or environmental components were discovered during adolescence. Nonetheless, by the age of 17, the majority of the mandibular traits are under either additive or dominant genetic impact.</p></div>","PeriodicalId":45449,"journal":{"name":"International Orthodontics","volume":"22 1","pages":"Article 100842"},"PeriodicalIF":1.5,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1761722723001213/pdfft?md5=c23735eda8eb80f927d6a8539436f6f6&pid=1-s2.0-S1761722723001213-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139433991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}