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Assessment of Nursing Knowledge About Care of Patients Diagnosed with Thalassemia Major 重度地中海贫血患者护理知识评估
Q4 Medicine Pub Date : 2023-10-31 DOI: 10.54393/pjhs.v4i10.1050
Sumaira Tabbasum, Tahira Khurram, . Hafiza Nabila, Iqra Saleem, Zaryab Khan, Hafiza Ummara Rasheed
Thalassemia is a life-threatening disease and patients with this require whole-life medical care. Nurses play the most important part in the care of such patients. Objective: To assess the knowledge among nurses who are dealing with and their role in the management of thalassemia patients. Methods: In this study, a pre-test and a post-test were conducted among nurses. In the study, a questionnaire was given to 150 nurses to fill out before and after the awareness session who were included in the study. Pre and post-mean score differences were found using the Wilcoxon test, and a relationship was determined between post-mean score and level of experience using Spearman correlation. Results: The mean age of the participants was 28.73± (3.15) years. Comparison of the nurses’ pre- and post-session mean knowledge scores revealed that the nurses’ post scores in knowledge (39.48±2.08) were higher than their pre-receiving guide scores (21.18±3.47) and that the difference was statistically significant (Z = -10.62, P = 0.000). Conclusions: According to the facts of this study, on the post-test, the level of thalassemia knowledge was higher among nurses who had received nursing care protocol training than among those who had not. Nursing level of experience and post-training sessions had a significant relationship.
地中海贫血是一种危及生命的疾病,患者需要终身医疗护理。护士在护理这类病人中起着最重要的作用。目的:了解地中海贫血护理人员的相关知识及其在地中海贫血患者管理中的作用。方法:对护理人员进行前测和后测。在这项研究中,150名护士在意识课程前后填写了一份调查问卷。使用Wilcoxon检验发现前后平均得分差异,并使用Spearman相关确定后平均得分与经验水平之间的关系。结果:患者平均年龄28.73±(3.15)岁。护理前后平均知识得分比较,护理后知识得分(39.48±2.08)高于护理前指导得分(21.18±3.47),差异有统计学意义(Z = -10.62, P = 0.000)。结论:根据本研究的事实,在后测中,接受过护理方案培训的护士对地中海贫血的知识水平高于未接受过护理方案培训的护士。护理经验水平与培训后课程有显著关系。
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引用次数: 0
Frequency of Foot Pain and Assessment of Foot Function Associated with Wearing Point Shoes in Students and Faculty Members of Fashion Designing Schools 服装设计学院师生穿尖头鞋后足部疼痛频率及足部功能评估
Q4 Medicine Pub Date : 2023-10-31 DOI: 10.54393/pjhs.v4i10.1093
Rabia Majeed, Muhammad Ammar Akbar, Maheen Waseem, Samer Zehra, Mamoona Shaukat
Pointed footwear inclines to remain trendy in the field of fashion design and causes discomfort and difficulty with daily activities. Objective: To determine and evaluate frequency of foot pain and assessment of foot function associated with wearing pointed shoes in students and faculty members of fashion designing schools. Methods: This cross-sectional study was conducted on fashion designing students and faculty members from December 2022 to May 2023 in Lahore, Pakistan. 396 participants between the ages of 18 and 50, of both genders with a minimum of 3 hours to a maximum of 8 hours wearing pointed shoes were included. Those with foot deformities or previous foot trauma were excluded. Foot and Ankle Ability Measure (FAAM) and Visual Analogue Scale (VAS) of pain were used. SPSS 25 was used for data analysis. Results: 51.52% reported moderate pain in their feet on Visual Analogue Scale, 30.81% people reported mild pain. 7.32% had no pain and 10.35% complained of severe foot pain. Chi-square test resulted in (110.859) and p-value of less than 0.05. Conclusions: The study concludes that wearing pointed shoes causes mild to moderate foot pain whereas significant impact was observed in their activities of daily living.
尖头鞋倾向于在时尚设计领域保持时尚,但会给日常活动带来不适和困难。目的:确定和评估服装设计学院师生穿尖头鞋时足部疼痛和足功能评估的频率。方法:本横断面研究于2022年12月至2023年5月在巴基斯坦拉合尔对服装设计专业的学生和教师进行了研究,包括396名参与者,年龄在18至50岁之间,男女,穿尖头鞋最少3小时至最多8小时。排除足部畸形或既往足部创伤者。采用足踝能力量表(FAAM)和疼痛视觉模拟量表(VAS)。采用SPSS 25进行数据分析。结果:51.52%的患者在视觉模拟量表中报告足部中度疼痛,30.81%的患者报告轻度疼痛。7.32%的患者没有疼痛,10.35%的患者抱怨足部疼痛严重。卡方检验结果为(110.859),p值小于0.05。结论:穿尖头鞋会引起轻度至中度足部疼痛,但对日常生活活动有显著影响。
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引用次数: 0
The Battle against Antibiotic Resistance: Exploring Perceptions, Misconceptions, Attitudes, Practices, and Awareness Factors Influencing Antibiotic Resistance among General and Clinical Populations 抗生素耐药性之战:探索认知、误解、态度、实践和意识因素影响抗生素耐药性的一般和临床人群
Q4 Medicine Pub Date : 2023-10-31 DOI: 10.54393/pjhs.v4i10.1011
Salman Zahir, Sarwat Jahan, Khansa Khan, Hashir Ul Jiyad, Zahoor Ahmad Khan, Zarghuna Akbar, Maria Iqbal, Atifa Afridi
Antibiotic resistance is rapidly advancing and becoming a higher risk over time; previously manageable infections have turned untreatable. Objective: To assess the perceptions, misconceptions, attitudes, practices, and awareness factors influencing antibiotic resistance among general and clinical populations. Methods: A total of 348 participants from the general public and 523 junior and senior medical practitioners in Peshawar, Pakistan, were included in this comparative observational cross-sectional study. Data were collected using a standardized questionnaire, which was later assessed by Chi-square test through SPSS version 26.0. Results: The results revealed a lack of awareness and knowledge regarding antibiotic resistance among both groups. Only 32% of the general public correctly identified the definition of antibiotic resistance, while 76% of medical practitioners demonstrated a basic understanding of the concept. However, a significant number of participants from both groups recognized the problem of bacterial infections resistant to all antibiotics and the contribution of self-medication to antibiotic resistance. In terms of self-medication practices, approximately 60% of the general public reported self-medicating with antibiotics without consulting a healthcare professional. Among medical practitioners, the rate of self-medication was significantly lower, but a small proportion still admitted to prescribing antibiotics without appropriate diagnosis or indications. The majority of participants, however, did not intend to prescribe/suggest unnecessary antibiotics. Conclusions: The findings indicated that both groups were cognizant of the issue, yet certain misconceptions persisted within each group.
抗生素耐药性正在迅速发展,并随着时间的推移成为更高的风险;以前可控制的感染已变得无法治疗。目的:评估普通人群和临床人群对抗生素耐药性的认知、误解、态度、做法和意识因素。方法:来自巴基斯坦白沙瓦的348名普通公众和523名初级和高级医生被纳入这项比较观察性横断面研究。采用标准化问卷收集数据,通过SPSS 26.0版本进行卡方检验。结果:结果显示两组患者对抗生素耐药性缺乏认识和知识。只有32%的普通公众正确地确定了抗生素耐药性的定义,而76%的医生对这一概念有基本的了解。然而,两组中有相当数量的参与者认识到细菌感染对所有抗生素都具有耐药性的问题,以及自我用药对抗生素耐药性的贡献。在自我用药实践方面,大约60%的公众报告在没有咨询医疗保健专业人员的情况下使用抗生素进行自我用药。在执业医师中,自我用药的比例明显较低,但仍有一小部分人承认在没有适当诊断或适应症的情况下开了抗生素。然而,大多数参与者并不打算开/建议不必要的抗生素。结论:研究结果表明,两组都认识到这个问题,但某些误解仍然存在于每组。
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引用次数: 0
Frequency of Uterine Rupture and Its Maternal and Fetal Outcomes of Uterine Rupture among Pregnant Women 妊娠妇女子宫破裂的频率及其母胎结局
Q4 Medicine Pub Date : 2023-10-31 DOI: 10.54393/pjhs.v4i10.1115
Aisha Seher, Arifa Yousafzai, Zakia Minhas, Sumera Brohi, Mehvish Masood, Maryum Noor, Adnan Fazal
A uterine rupture is when the uterine wall is torn during labor or right after birth. It is although not common but when occurs it is catastrophic obstetrical emergency for both mother and fetus needs prompt diagnosis and expert management. Moreover it may leads women to irreversible infertility as it rottenly ends at hysterectomy. Objective: To determine the frequency of uterine rupture and its maternal and fetal outcomes among pregnant women. Methods: This Cross Sectional study was conducted at Civil Hospital Karachi in the department of Obstetrics and Gynecology Unit II from 8th December 2018 to 7th June 2019. A total of 317 pregnant women of gestational age >28 weeks, fulfilling the inclusion criteria were enrolled .The data were collected on prepared proforma. Results: This study includes 317 patients with age ranges from 25 to 35 years with mean age of 28.44 ± 3.62 years. In this study, frequency of uterine rupture among pregnant women was found in 7(2.2%) women and maternal mortality 1(7.69%). Conclusions: Findings of this study suggests that uterine perforation is still high and remained important factor for maternal and fetal outcome.
子宫破裂是指在分娩过程中或分娩后子宫壁撕裂。虽然不常见,但一旦发生,对母亲和胎儿都是灾难性的产科急诊,需要及时诊断和专家管理。此外,它可能导致妇女不可逆转的不孕症,因为它在子宫切除术中腐烂结束。目的:了解妊娠妇女子宫破裂的发生率及其母婴结局。方法:本横断面研究于2018年12月8日至2019年6月7日在卡拉奇民用医院妇产科第二单元进行。共纳入317名符合纳入标准的孕龄(28周)孕妇。数据收集采用准备好的形式表格。结果:本研究纳入317例患者,年龄25 ~ 35岁,平均年龄28.44±3.62岁。本组孕妇子宫破裂发生率为7例(2.2%),产妇死亡率为1例(7.69%)。结论:本研究结果提示子宫穿孔率仍然很高,仍然是影响母胎结局的重要因素。
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引用次数: 0
Lifestyle Impacts of Extended Nursing Shifts Among Nurses: A Study in Tertiary Care Hospitals in Karachi, Pakistan 延长护理轮班对护士生活方式的影响:巴基斯坦卡拉奇三级护理医院的研究
Q4 Medicine Pub Date : 2023-10-31 DOI: 10.54393/pjhs.v4i10.1054
Rasheed Ahmed Khan, Tahir Ali, Nasir Mehmood, Nighat Riaz, Usman Ghani, Talat Riaz, Afsha Bibi, Nasar Khan, Abdul Nasir
A significant concern in healthcare settings is extended hours' effect on nurses' health. Objective: This study aims to explore the lifestyle impacts of extended nursing shifts among nurses at tertiary care hospitals in Karachi, Pakistan. Methods: This cross-sectional study was conducted in three tertiary care hospitals in Karachi, Pakistan, among 100 nurses. Results: Study findings reveal that majority, 87%, believe it hinders decision-making, while 88% see sleep deficits and 88% note time constraints for exercise. Communication quality is a concern for 76%. 78% see knowledge transfer issues when nurses hand over responsibilities, and 58% think religious activities are impacted. Opinions vary on patient care quality (50% positive). Stress levels concern 80%, social lives are disrupted for 91%, and physical health effects concern 93%. Additional worries include inadequate diet (39%), nurses working long shifts are exhausted (91%), child care neglect (89%), altered eliminatory patterns (84%), life expectancy (32%), memory problems (69%), hormonal disruptions (76%), workplace conflicts (88%), and infection risk (88%). Finally, 76% perceive high absenteeism. Conclusions: The findings underscore significant concerns about the negative impact of long working hours on nurses' health and performance. To address these issues, it is recommended that healthcare institutions prioritize implementing structured shift rotations and providing adequate breaks to mitigate the adverse effects of extended shifts on nurses' wellbeing and patient care quality.
医疗机构的一个重大关切是延长工作时间对护士健康的影响。目的:本研究旨在探讨延长护理轮班对巴基斯坦卡拉奇三级医院护士生活方式的影响。方法:本横断面研究在巴基斯坦卡拉奇的三所三级医院进行,共有100名护士。结果:研究结果显示,87%的人认为睡眠不足会影响决策,88%的人认为睡眠不足,88%的人认为锻炼时间有限。76%的人担心沟通质量。78%的人认为护士移交职责时存在知识转移问题,58%的人认为宗教活动受到影响。对病人护理质量的看法各不相同(50%持肯定态度)。压力水平占80%,社交生活中断占91%,身体健康影响占93%。其他担忧包括饮食不足(39%)、长时间轮班的护士筋疲力尽(91%)、忽视儿童保育(89%)、排尿模式改变(84%)、预期寿命(32%)、记忆问题(69%)、荷尔蒙紊乱(76%)、工作场所冲突(88%)和感染风险(88%)。最后,76%的人认为旷工率很高。结论:研究结果强调了长时间工作对护士健康和绩效的负面影响。为了解决这些问题,建议医疗机构优先实施有组织的轮班轮换,并提供足够的休息时间,以减轻延长轮班对护士福祉和患者护理质量的不利影响。
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引用次数: 0
Effectiveness of Standardized Nursing Care Plan on Nurses’ Usability Regarding Quality Nursing Care in Private Tertiary Care Hospital Lahore 拉合尔私立三级医院规范化护理计划对护士对优质护理可用性的影响
Q4 Medicine Pub Date : 2023-10-31 DOI: 10.54393/pjhs.v4i10.1113
Misbah Hanif, Sarfraz Masih
Nursing care entails both an art and a science, involving the provision of tailored patient care based on individual healthcare requirements. The nursing care plan is instrumental, serving as a precise guide for nurses in delivering patient-centered, high-quality care. It functions as a roadmap, enabling nurses to monitor the patient's response to treatment and make necessary adjustments to meet medical needs. Challenges such as excessive workload, absence of policies, inadequate resources, understaffing, and unavailability of assessment forms hinder the effective utilization of nursing care plans Objective: To evaluate the effect of standardized nursing care plan on nurses` usability of nursing process during patient care. Methods: A quasi-experimental study was conducted at a Tertiary Care hospital Lahore Pakistan. A stratified Random sample of n=47 participants intervention group was recruited. A validated questionnaire of Nurses’ usability of standardized nursing care plan consisted of 23 items. Data were analyzed through SPSS version 21. Results: Majority of the participants 44.7% (n=21) were between 26-30 years of age, 46.8% of the participants (n=22) had working experience between 1-4 years, 70.2% (n=33) of them having nursing diploma, 23.4% (n=11) were attained Post RN BSN. A significant difference was found between Nurses` usability scores before and after intervention as evident by p=0.000 with mean and SD of 2.8085+0.79778 and 3.7872+0.41369, respectively. Conclusions: It is evident from results that standardized nursing care plan has a significant effect on nurse’s usability that improve the quality of nursing care in Hospital.
护理既是一门艺术,也是一门科学,涉及根据个人医疗保健需求提供量身定制的患者护理。护理计划是工具性的,作为护士提供以病人为中心的高质量护理的精确指南。它可以作为路线图,使护士能够监测患者对治疗的反应,并做出必要的调整以满足医疗需求。工作量过大、政策缺失、资源不足、人员编制不足、考核表不到位等挑战阻碍了护理计划的有效利用。目的:评价规范化护理计划对护士护理过程可用性的影响。方法:在巴基斯坦拉合尔一家三级医院进行准实验研究。采用分层随机抽样,干预组共47人。一份经过验证的护士标准化护理计划可用性问卷包括23个项目。数据采用SPSS version 21进行分析。结果:44.7% (n=21)的参与者年龄在26-30岁之间,46.8% (n=22)的参与者有1-4年的工作经验,70.2% (n=33)的参与者有护理文凭,23.4% (n=11)的参与者获得了注册护士后的BSN。干预前后护士可用性得分差异有统计学意义,p=0.000,均数为2.8085+0.79778,标准差为3.7872+0.41369。结论:规范化护理计划对提高医院护理质量的护士可用性有显著作用。
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引用次数: 0
Efficacy of Muscle Energy Technique alone and in combination with Interferential Therapy for the Treatment of Non-specific Low Back Pain 肌能技术单独及联合干预治疗非特异性腰痛的疗效观察
Q4 Medicine Pub Date : 2023-10-31 DOI: 10.54393/pjhs.v4i10.1122
Ali Zubair, Imama Shakoor, Muhammad Saad Hassan, Shumaila Tahreem, Mehwish Iqbal, Kiran Haq, Muhammad Salman
Non-specific back pain is one of the prevalent musculoskeletal disorders in general population worldwide and also a major contributor of days lost from the work. It is considered one of the major causes of financial burden on the healthcare. Objective: To compare the effectiveness of muscle energy technique alone and in combination with interferential therapy in the management of non-specific back pain. Methods: After getting the review ethical committee approval from The Neurocounsel Clinics, current RCT was initiated from 21 May, 2023 to 20 September 2023 and registered at ClinicalTrails.gov under NCT06098053. Sample size was calculated by Epitool which came 30. Simple random sampling technique was used to randomize participants into two equal groups. Group A was given muscle energy technique and group B was given muscle energy technique plus interferential therapy. 2 sessions/week for 4 & half weeks. Evaluation was done at pain numeric scale & EQ-5D-5L (QoL). Pre and post-test analysis was done by use of SPSS version 21 and level of significance was kept p<0.05. Results: The mean age in group A was 31.40±10.91 whereas in group B it was 26.93±11.69. Mann Whitney U test showed significant difference (p<0.05) between groups on the basis of PNS and insignificant difference (p>0.05) between groups on the basis of QoL. Conclusions: It was concluded from the results of this study that MET and IFT are more effective in alleviating patient’s pain but are equally effective in improving quality of life in patients suffering from non-specific back pain.
非特异性背部疼痛是世界范围内普遍存在的肌肉骨骼疾病之一,也是造成工作损失的主要原因。它被认为是医疗保健财政负担的主要原因之一。目的:比较单用肌能技术与联合干预治疗非特异性腰痛的疗效。方法:在获得the Neurocounsel Clinics的审查伦理委员会批准后,本RCT于2023年5月21日至2023年9月20日启动,并在ClinicalTrails.gov注册,编号为NCT06098053。样本大小由Epitool计算,结果为30。采用简单随机抽样技术将参与者随机分为两组。A组采用肌能技术,B组采用肌能技术加干预治疗。2节/周,4 &半周。评估是在疼痛数值量表&EQ-5D-5L (QoL)。采用SPSS version 21进行前后分析,显著性水平为p<0.05。结果:A组平均年龄为31.40±10.91岁,B组平均年龄为26.93±11.69岁。Mann Whitney U检验显示PNS组间差异显著(p>0.05), QoL组间差异不显著(p>0.05)。结论:本研究结果表明MET和IFT在缓解患者疼痛方面更有效,但在改善非特异性腰痛患者的生活质量方面同样有效。
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引用次数: 0
Effectiveness of Nurse-led Educational Intervention on Therapeutic Communication of Undergraduate Nursing Students by Using SBAR tool 用SBAR工具对护理本科学生治疗性沟通进行护理主导教育干预的效果观察
Q4 Medicine Pub Date : 2023-10-31 DOI: 10.54393/pjhs.v4i10.1026
Aleena Ilyas, Amjad Ali, Tanseer Ahmed
Efficient communication is most noteworthy because it impacts patient quality care. A prepared tool can useful to adequately impart patient data, lessen unfavorable incidents, improve patient safety, enhance quality of care, and amplify the healthcare team members’ satisfaction. Objective: To identify the effectiveness of nurse-led educational intervention on therapeutic communication of undergraduate nursing students by using the SBAR tool. Methods: This pre & post-quasi-experimental study was conducted from Jan-2021 to May-2021 among 120 undergraduate students from two different nursing institutions in Karachi by using a purposive sampling technique. Ethical approval was obtained and written informed consent was taken from each participant in the study. Data was collected by adopting the SBAR tool comprising 10 multiple-choice questions. Nurse-led educational intervention was provided after pre-assessment through lectures and discussion in the classroom. Data were analyzed using SPSS version-23. Results: Results showed a mean ± SD of age 30.44±5.40 varied from 23 to 51 years. Most of the participants (51.7%) were female and 70.8% of the participants had working experience ranging from 2 to 10 years. In the pre-test assessment, most of the participants secured a 4 out of 10 score (25.0%) whereas 8 out of 10 score (29.2%) in the post-test. A significant impact on the knowledge of undergraduate nursing students after educational intervention (p<0.001) was seen. Conclusions: This study concludes that undergraduate student nurses have very low knowledge related to the SBAR tool for therapeutic communication. Nurse-led education interventions improve nursing knowledge and understanding of the SBAR tool, as evident by post-test scores.
有效的沟通是最值得注意的,因为它影响病人的护理质量。准备好的工具有助于充分传达患者数据、减少不利事件、改善患者安全、提高护理质量并提高医疗团队成员的满意度。目的:应用SBAR工具,探讨护士主导教育干预对护理本科学生治疗性沟通的影响。方法:本预采用目的抽样方法,于2021年1月至2021年5月对来自卡拉奇两家不同护理机构的120名本科生进行准实验后研究。获得了伦理批准,并从研究的每个参与者那里获得了书面知情同意。数据收集采用SBAR工具,包括10个选择题。通过讲座和课堂讨论进行预评估后,进行护士主导的教育干预。数据采用SPSS version-23进行分析。结果:23 ~ 51岁,平均±SD 30.44±5.40。大部分受访者(51.7%)为女性,70.8%的受访者工作经验介乎2至10年。在测试前评估中,大多数参与者获得了10分中的4分(25.0%),而在测试后获得了10分中的8分(29.2%)。教育干预对本科护生的知识有显著影响(p<0.001)。结论:本研究认为本科护生对SBAR治疗沟通工具的相关知识非常低。从测试后得分可以看出,护士主导的教育干预措施提高了护理知识和对SBAR工具的理解。
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引用次数: 0
Concordance and Discordance between Radiology Resident’s and Radiologist’s Interpretation of Brain MRI in Patients with Head Masses 放射科住院医师与放射科医师对头部肿块患者脑MRI解释的一致性与不一致性
Q4 Medicine Pub Date : 2023-10-31 DOI: 10.54393/pjhs.v4i10.1078
Khadeeja Anwar, Abdullah Safi, Hadia Abid, Irfanullah Khan, Umar Anwar, Talha Anwar, Anisa Sundal
Diagnosis of head masses involves clinical examination, neurological signs, and radiological imaging. MRI is the preferred imaging tool for detailed assessment of tumor, its extent and treatment plan. Objective: To find the level of concordance and discordance between radiology resident’s and consultant’s interpretation of MRI (Magnetic Resonance Imaging) done for brain masses. Methods: A cross sectional study was conducted at the radiology department of Rehman Medical Institute, Peshawar. Simple random sampling was done and sample size was calculated using kappa coefficients (Donner and Rotondi) n=100. 100 patients who visited department of Radiology over a period of two years were assessed by prospective analysis of their radiology reports. Senior resident’s and consultant’s reports were compared. All pre-op patients were included irrespective of age or gender. Data were collected and recorded on a specially designed proforma and entered into Microsoft excel and analyzed using SPSS (Version 22.0. IBM Corp., Armonk, NY). Results: MRI brain reports of 58 male and 42 female patients were evaluated. The most common tumors were gliomas, making up 52% of the total tumors. Metastasis being second most common tumor making 16%, meningiomas in 15%, pituitary tumors in 10% and vestibular schwannomas in 7% of the patients. Concordance, discordance, and Cohen’s Kappa values in different masses were gliomas. (Concordance=88.46%, Discordance=11.54%, k=0.336), Meningiomas (Concordance=86.66%, Discordance=13.34%, k=0.423), Metastasis (Concordance=81.25%, Discordance=18.75%, k=0.294), Pituitary Tumors (Concordance=80%) Discordance=20%, k=0.375) and Vestibular Schwannomas (Concordance=85.71%, Discordance= 14.29% k=0.588). Conclusions: There was no statistically significant difference between senior resident’s and consultant radiologist’s report of MRI brain masses.
头部肿块的诊断包括临床检查、神经学征象和放射影像学检查。MRI是详细评估肿瘤、肿瘤范围和治疗方案的首选成像工具。目的:探讨住院医师与会诊医师对脑肿块MRI(磁共振成像)解释的一致与不一致程度。方法:横断面研究在白沙瓦Rehman医学研究所放射科进行。采用简单随机抽样,采用kappa系数(Donner and Rotondi) n=100计算样本量。采用前瞻性分析方法对两年内来放射科就诊的100例患者的放射学报告进行评估。比较了高级住院医师和顾问的报告。所有术前患者不论年龄或性别均纳入研究。数据收集并记录在专门设计的表格上,输入Microsoft excel,并使用SPSS (Version 22.0)进行分析。IBM Corp.,纽约州阿蒙克市)。结果:对58例男性和42例女性患者的MRI脑报告进行了评估。最常见的肿瘤是胶质瘤,占肿瘤总数的52%。转移是第二常见的肿瘤,占16%,脑膜瘤占15%,垂体瘤占10%,前庭神经鞘瘤占7%。不同肿块的一致性、不一致性和Cohen’s Kappa值均为胶质瘤。(一致性=88.46%,不一致性=11.54%,k=0.336)、脑膜瘤(一致性=86.66%,不一致性=13.34%,k=0.423)、转移瘤(一致性=81.25%,不一致性=18.75%,k=0.294)、垂体瘤(一致性=80%)不一致性=20%,k=0.375)和前庭神经鞘瘤(一致性=85.71%,不一致性= 14.29%,k=0.588)。结论:老年住院医师与放射科顾问医师对MRI脑肿块的报告无统计学差异。
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引用次数: 0
Quantification of Heavy Metals and Chemical Stressors in Ground Water of Coal Mining Areas and Associated Human Health Risk 煤矿矿区地下水中重金属和化学物质的定量分析及其对人体健康的危害
Q4 Medicine Pub Date : 2023-10-31 DOI: 10.54393/pjhs.v4i10.1114
Aima Iram Batool, Fariha Idrees, Areesha Khannum, Naima Huma Naveed, Muhammad Fayyaz Ur Rehman, Aksa Akram, Syed Sikandar Habib, Hakim Bibi
Acid mine drainage is one of the most obvious challenges in coal mining areas that is responsible for deteriorating soil and ground water quality of nearby communities thus posing serious human health risk. Objective: To quantify of heavy metals and chemical stressors in ground water and associated human health risk. Methods: Cross-sectional study with a combination of random sampling and Probability-Proportional-to-Size Sampling was used. Eight different sites were selected for water sample collection, and heavy metals were quantified. The analysis was carried out. Physicochemical properties of water were assessed using a portable photometer. Hematological parameters and antioxidants in the blood of study subjects were also measured. Results: Among the water samples, site S1 had the highest iron concentration at 0.354 ppm, exceeding the US limit of 0.3 ppm, with nickel being the next most abundant metal. Site S8 recorded the highest temperature at 36.4°C, while site S5 had the highest pH in the drinking water. The maximum electrical conductivity was found at S4 with 1387 s/m, and the total dissolved solvent parameter peaked at 1598 ppm in S8. Subjects exposed to acid mine drainage through water consumption displayed significant changes in antioxidant and blood parameters compared to the control group. In the exposed group, catalase (63.47), superoxide dismutase (33.26), and glutathione peroxidase (532.97) levels decreased, while malondialdehyde levels increased to 1.39. Conclusions: The physical and chemical properties of all water resources of mining areas were negatively altered due to heavy metals contamination thus poses a serious threat of oxidative stress in exposed subjects.
酸性矿井排水是煤矿矿区最明显的挑战之一,它导致附近社区土壤和地下水质量恶化,从而对人类健康构成严重威胁。目的:定量分析地下水中重金属和化学应激源及其对人体健康的危害。方法:采用随机抽样和概率比例抽样相结合的横断面研究方法。选取8个不同地点采集水样,对重金属进行了定量分析。进行了分析。用便携式光度计测定了水的物理化学性质。还测量了研究对象血液中的血液学参数和抗氧化剂。结果:在水样中,S1站点的铁含量最高,为0.354 ppm,超过了美国0.3 ppm的限量,其次是镍。S8站点的最高温度为36.4°C,而S5站点的饮用水pH值最高。S4的电导率最高,为1387 s/m; S8的总溶解溶剂参数最高,为1598 ppm。与对照组相比,通过饮水暴露于酸性矿井废水的受试者在抗氧化和血液参数方面表现出显著变化。暴露组过氧化氢酶(63.47)、超氧化物歧化酶(33.26)和谷胱甘肽过氧化物酶(532.97)水平下降,丙二醛水平上升至1.39。结论:重金属污染对矿区所有水资源的理化性质都产生了负面影响,对暴露对象造成了严重的氧化应激威胁。
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Pakistan Journal of Medical & Health Sciences
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