Pub Date : 2023-10-31DOI: 10.54393/pjhs.v4i10.1100
Sanjay Gandhi, Haris Khan, Umer Bin Tariq, Gulfan Ullah, Akmal Zubair
The research looks at access to the radial artery in contemporary medicine to lower the occurrence of acute kidney injury (AKI). In an effort to increase patient-centered procedural safety, it evaluates evidence contrasting radial versus femoral access. Objective: To determine if access to the radial artery and the prevalence of AKI during interventional procedures, with an emphasis on evaluating the possible advantages of radial access in lowering the risk of AKI. Methods: An examination of 132 instances classified by access location (radial artery as opposed to other sites) was done retrospectively. Beginning in September 2022 and ending in March 2023, the study's length was six months. AKI incidence, procedure specifics, and demographic data were compared. The independent influence of radial access on the risk of AKI was evaluated using multivariate logistic regression. Results: The radial artery group (13.6%) exhibited a significantly lower AKI incidence than the comparator group (27.3%). Multivariate analysis confirmed the independent association. Conclusions: The possible relevance of access to the radial artery in reducing post-procedural AKI highlights the possibility of a safer alternative. Evidence-based access site selection is becoming more crucial in the age of patient-centered healthcare to improve procedural outcomes.
{"title":"Association of Access to the Radial Artery with Reduced Incidence of Acute Kidney Injury","authors":"Sanjay Gandhi, Haris Khan, Umer Bin Tariq, Gulfan Ullah, Akmal Zubair","doi":"10.54393/pjhs.v4i10.1100","DOIUrl":"https://doi.org/10.54393/pjhs.v4i10.1100","url":null,"abstract":"The research looks at access to the radial artery in contemporary medicine to lower the occurrence of acute kidney injury (AKI). In an effort to increase patient-centered procedural safety, it evaluates evidence contrasting radial versus femoral access. Objective: To determine if access to the radial artery and the prevalence of AKI during interventional procedures, with an emphasis on evaluating the possible advantages of radial access in lowering the risk of AKI. Methods: An examination of 132 instances classified by access location (radial artery as opposed to other sites) was done retrospectively. Beginning in September 2022 and ending in March 2023, the study's length was six months. AKI incidence, procedure specifics, and demographic data were compared. The independent influence of radial access on the risk of AKI was evaluated using multivariate logistic regression. Results: The radial artery group (13.6%) exhibited a significantly lower AKI incidence than the comparator group (27.3%). Multivariate analysis confirmed the independent association. Conclusions: The possible relevance of access to the radial artery in reducing post-procedural AKI highlights the possibility of a safer alternative. Evidence-based access site selection is becoming more crucial in the age of patient-centered healthcare to improve procedural outcomes.","PeriodicalId":45690,"journal":{"name":"Pakistan Journal of Medical & Health Sciences","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135978254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
None Muhammad Wasim Sajjad, None Sarmad Saeed khattak, None Saif Ullah, None Azam Jan, None Muhammad Salman Farsi, None Rashid Qayyum, None Marghalara Bangash
Concomitant CABG is performed in combination with other cardiac procedures (VHD, CHD) while CABG is performed exclusively for CAD. Objective: To compare the mortality and perioperative outcomes between CABG and concomitant CABG for proper quoting of risk & optimizing the treatment decision for improved patient outcomes. Methods: The observational study on retrospective data was conducted at Rehman Medical Institute from December 2020 to December 2022. A total of 169 patients were included, with 89 in the CABG and 80 in the concomitant CABG group. Ethical approval was granted and inclusion criteria were met. Data were analyzed using SPSS 25. Results: A total of 169 patients were included with a mean age of 57.72±10.65 & the majority of the male population (77.5%). Most of the patients had NYHA III (56.1%) & CCS III (43.9%) class symptoms. Hypertension was our most common co-morbidity (58.0%), followed by dyslipidemia (52.3%) & DM (47.3%). Concomitant CABG has the worst parameters in terms of intraoperative characteristics such as a statistically significant higher rate of intraoperative transfusion (p <0.001), prolonged perfusion (p <0.001) & cross-clamp time (p<0.001). Similarly, concomitant CABG patients have the worst postoperative outcomes with a significantly higher incidence of mortality (p <0.001), post-operative transfusion requirement (p 0.008), increased duration of mechanical ventilation hours (p 0.005), extended hours of ICU stay (p 0.02) & higher rates of re-intubation (p 0.03). Conclusions: Concomitant CABG is no doubt a high-risk procedure as signified by its worst outcomes.
{"title":"Concomitant CABG vs. CABG Alone - A Comparative Analysis of Early Outcomes","authors":"None Muhammad Wasim Sajjad, None Sarmad Saeed khattak, None Saif Ullah, None Azam Jan, None Muhammad Salman Farsi, None Rashid Qayyum, None Marghalara Bangash","doi":"10.54393/pjhs.v4i09.986","DOIUrl":"https://doi.org/10.54393/pjhs.v4i09.986","url":null,"abstract":"Concomitant CABG is performed in combination with other cardiac procedures (VHD, CHD) while CABG is performed exclusively for CAD. Objective: To compare the mortality and perioperative outcomes between CABG and concomitant CABG for proper quoting of risk & optimizing the treatment decision for improved patient outcomes. Methods: The observational study on retrospective data was conducted at Rehman Medical Institute from December 2020 to December 2022. A total of 169 patients were included, with 89 in the CABG and 80 in the concomitant CABG group. Ethical approval was granted and inclusion criteria were met. Data were analyzed using SPSS 25. Results: A total of 169 patients were included with a mean age of 57.72±10.65 & the majority of the male population (77.5%). Most of the patients had NYHA III (56.1%) & CCS III (43.9%) class symptoms. Hypertension was our most common co-morbidity (58.0%), followed by dyslipidemia (52.3%) & DM (47.3%). Concomitant CABG has the worst parameters in terms of intraoperative characteristics such as a statistically significant higher rate of intraoperative transfusion (p <0.001), prolonged perfusion (p <0.001) & cross-clamp time (p<0.001). Similarly, concomitant CABG patients have the worst postoperative outcomes with a significantly higher incidence of mortality (p <0.001), post-operative transfusion requirement (p 0.008), increased duration of mechanical ventilation hours (p 0.005), extended hours of ICU stay (p 0.02) & higher rates of re-intubation (p 0.03). Conclusions: Concomitant CABG is no doubt a high-risk procedure as signified by its worst outcomes.","PeriodicalId":45690,"journal":{"name":"Pakistan Journal of Medical & Health Sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135038363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Imran Jariullah, Muhammad Ghayasuddin, Syeda Alisha Ali Zaidi, Muhammad Ali, Wahb Noor Zia, Ramsha Waseem, Zaffar Ali, Khadijah Abid
Umbilical and paraumbilical hernias are common conditions affecting a significant portion of the global population, with surgical intervention being a common treatment modality. Seroma formation is a common complication after hernioplasty. Tranexamic acid (TXA) has emerged as a promising prophylactic agent for seroma prevention, as it inhibits fibrin breakdown, reducing blood loss and blood transfusions. Objective: To evaluate the role of intravenous tranexamic acid in the prevention of seroma formation after umbilical and paraumbilical hernioplasty. Methods: It was a cohort study conducted at the department of surgery, Kulsoom Bai Valika Hospital, Karachi, Pakistan from Oct 2022 to Apr 2022. Patients aged 18 years or above who underwent umbilical and paraumbilical hernioplasty of either gender were involved in the study. The individuals were then categorized into two groups: the exposed group, consisting of patients who received intravenous tranexamic acid (IVTXA), and the unexposed group, comprising of patients who did not receive IVTXA. Both groups were monitored for a duration of three months to assess the incidence of seroma formation. Results: Out of 30 patients in each group, 4 patients (13.3%) in the IVTXA group developed seroma, while 26 patients (86.7%) in the Without TXA group developed seroma. This difference was statistically significant with p-value=0.0021. The risk of seroma formation is 0.22 times lesser in patients with intravenous tranexamic acid as compared to patients without tranexamic acid (RR=0.22, 95% CI: 0.12-0.91). Conclusions: IVTXA may be effective in preventing seroma formation after umbilical and paraumbilical hernioplasty.
脐疝和脐旁疝是影响全球很大一部分人口的常见疾病，手术干预是一种常见的治疗方式。血清肿形成是疝成形术后常见的并发症。氨甲环酸(TXA)已成为一种很有前途的预防血清肿的药物，因为它可以抑制纤维蛋白分解，减少失血和输血。目的:探讨静脉注射氨甲环酸对脐疝及脐旁疝成形术后血清肿形成的预防作用。方法:采用队列研究方法，于2022年10月至2022年4月在巴基斯坦卡拉奇Kulsoom Bai Valika医院外科进行。年龄在18岁或以上，接受过脐疝和脐旁疝成形术的患者，无论性别，都参与了这项研究。然后将这些个体分为两组:暴露组，由接受静脉注射氨甲环酸(IVTXA)的患者组成;未暴露组，由不接受IVTXA的患者组成。对两组患者进行为期三个月的监测，以评估血清肿形成的发生率。结果:每组30例患者中，IVTXA组有4例(13.3%)发生血肿，而无TXA组有26例(86.7%)发生血肿。差异有统计学意义，p值=0.0021。静脉注射氨甲环酸的患者与不注射氨甲环酸的患者相比，血清形成的风险低0.22倍(RR=0.22, 95% CI: 0.12-0.91)。结论:IVTXA可有效预防脐疝及脐旁疝成形术后血清肿的形成。
{"title":"Role of Intravenous Tranexamic Acid in Prevention of Seroma Formation after Umbilical and Para Umbilical Hernioplasty","authors":"Imran Jariullah, Muhammad Ghayasuddin, Syeda Alisha Ali Zaidi, Muhammad Ali, Wahb Noor Zia, Ramsha Waseem, Zaffar Ali, Khadijah Abid","doi":"10.54393/pjhs.v4i09.910","DOIUrl":"https://doi.org/10.54393/pjhs.v4i09.910","url":null,"abstract":"Umbilical and paraumbilical hernias are common conditions affecting a significant portion of the global population, with surgical intervention being a common treatment modality. Seroma formation is a common complication after hernioplasty. Tranexamic acid (TXA) has emerged as a promising prophylactic agent for seroma prevention, as it inhibits fibrin breakdown, reducing blood loss and blood transfusions. Objective: To evaluate the role of intravenous tranexamic acid in the prevention of seroma formation after umbilical and paraumbilical hernioplasty. Methods: It was a cohort study conducted at the department of surgery, Kulsoom Bai Valika Hospital, Karachi, Pakistan from Oct 2022 to Apr 2022. Patients aged 18 years or above who underwent umbilical and paraumbilical hernioplasty of either gender were involved in the study. The individuals were then categorized into two groups: the exposed group, consisting of patients who received intravenous tranexamic acid (IVTXA), and the unexposed group, comprising of patients who did not receive IVTXA. Both groups were monitored for a duration of three months to assess the incidence of seroma formation. Results: Out of 30 patients in each group, 4 patients (13.3%) in the IVTXA group developed seroma, while 26 patients (86.7%) in the Without TXA group developed seroma. This difference was statistically significant with p-value=0.0021. The risk of seroma formation is 0.22 times lesser in patients with intravenous tranexamic acid as compared to patients without tranexamic acid (RR=0.22, 95% CI: 0.12-0.91). Conclusions: IVTXA may be effective in preventing seroma formation after umbilical and paraumbilical hernioplasty.","PeriodicalId":45690,"journal":{"name":"Pakistan Journal of Medical & Health Sciences","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135039483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-30DOI: 10.54393/pjhs.v4i09.1109
Hidayat Ullah, Muhammad Shafique Arshad, Zabih Ullah, Abdul Rehman, Muhammad Khalil, Nouman Khan
Coronary angiography is a common procedure used to identify coronary artery disease. Whether femoral or radial vascular access is employed may impact radiation dosage and contrast dye utilization. This study examined radiation exposure and contrast dye volume in femoral and radial approach in patients undergoing coronary angiography. Objective: To assess and compare the radiation dosage and contrast dye volume between patients having coronary angiography through the femoral and radial routes. Methods: A prospective study included 408 consecutive coronary angiography patients from April 10 to August 31, 2023. The remaining 206 patients were treated radially, while 202 were treated femorally. We examined radiation exposure, dose area product (DAP), and contrast dye volume among groups. Results: Radial and femoral groups had similar mean ages (64.4±12.1 vs. 64.8±11.6, p=0.86). The radial group had 60.67% men versus 71.3% in femoral group. Radial and femoral catheterization radiation doses were 1.199 Gy (0.677-2.001) and 1.218 Gy (0.696-2.207), respectively, with a p-value of 0.88 showing no group radiation exposure difference. The group analysis found no hemorrhagic consequences from radial or femoral catheterization, coronarography, or angioplasty. Conclusions: The study participants noticed non-significant differences in contrast dye volume and radiation dose between femoral and radial coronary angiography.
{"title":"Comparison of Radiation Dose and Contrast Dye Volume Comparison in Coronary Angiography Via Femoral and Radial Routes","authors":"Hidayat Ullah, Muhammad Shafique Arshad, Zabih Ullah, Abdul Rehman, Muhammad Khalil, Nouman Khan","doi":"10.54393/pjhs.v4i09.1109","DOIUrl":"https://doi.org/10.54393/pjhs.v4i09.1109","url":null,"abstract":"Coronary angiography is a common procedure used to identify coronary artery disease. Whether femoral or radial vascular access is employed may impact radiation dosage and contrast dye utilization. This study examined radiation exposure and contrast dye volume in femoral and radial approach in patients undergoing coronary angiography. Objective: To assess and compare the radiation dosage and contrast dye volume between patients having coronary angiography through the femoral and radial routes. Methods: A prospective study included 408 consecutive coronary angiography patients from April 10 to August 31, 2023. The remaining 206 patients were treated radially, while 202 were treated femorally. We examined radiation exposure, dose area product (DAP), and contrast dye volume among groups. Results: Radial and femoral groups had similar mean ages (64.4±12.1 vs. 64.8±11.6, p=0.86). The radial group had 60.67% men versus 71.3% in femoral group. Radial and femoral catheterization radiation doses were 1.199 Gy (0.677-2.001) and 1.218 Gy (0.696-2.207), respectively, with a p-value of 0.88 showing no group radiation exposure difference. The group analysis found no hemorrhagic consequences from radial or femoral catheterization, coronarography, or angioplasty. Conclusions: The study participants noticed non-significant differences in contrast dye volume and radiation dose between femoral and radial coronary angiography.","PeriodicalId":45690,"journal":{"name":"Pakistan Journal of Medical & Health Sciences","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135131351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-30DOI: 10.54393/pjhs.v4i09.1019
Anum Farhan, Sidra Tariq, Maria Tasneem, Daniya Khan, Sanam Chachar, Hamna Sabih Baqai, Kamran Fazal
Preterm birth and low birth weight are just two negative fetal outcomes that are linked to PIH. The WHO divides infants into three categories based on birth weight and gestational age: Small for gestational age, Appropriate for gestational age, and Large for gestational age. LBW babies are those who weigh less than 2.5kg within 24 hours of birth, according to these standards. Objectives: To determine the frequency of low birth weight in patients with gestational hypertension. Methods: This Descriptive study was done in department of Obstetrics and Gynecology unit III, Civil Hospital Karachi from 16th February 2019 to 15th August 2019. We enrolled 89women diagnosed with gestational hypertension meeting the criteria. Informed consent was taken. Results: Age range in this study was from 20 to 45 years with majority of the patients 52 (58.43%) were between 18 to 30 years of age. Mean gestational age was 39.51±2.7 weeks. Frequency of low birth weight in patients with gestational hypertension was found in 27 (30.34%) patients. Conclusions: This study concluded that frequency of low birth weight in patients with gestational hypertension is very high.
{"title":"Frequency of Low Birth Weight in Patients with Gestational Hypertension","authors":"Anum Farhan, Sidra Tariq, Maria Tasneem, Daniya Khan, Sanam Chachar, Hamna Sabih Baqai, Kamran Fazal","doi":"10.54393/pjhs.v4i09.1019","DOIUrl":"https://doi.org/10.54393/pjhs.v4i09.1019","url":null,"abstract":"Preterm birth and low birth weight are just two negative fetal outcomes that are linked to PIH. The WHO divides infants into three categories based on birth weight and gestational age: Small for gestational age, Appropriate for gestational age, and Large for gestational age. LBW babies are those who weigh less than 2.5kg within 24 hours of birth, according to these standards. Objectives: To determine the frequency of low birth weight in patients with gestational hypertension. Methods: This Descriptive study was done in department of Obstetrics and Gynecology unit III, Civil Hospital Karachi from 16th February 2019 to 15th August 2019. We enrolled 89women diagnosed with gestational hypertension meeting the criteria. Informed consent was taken. Results: Age range in this study was from 20 to 45 years with majority of the patients 52 (58.43%) were between 18 to 30 years of age. Mean gestational age was 39.51±2.7 weeks. Frequency of low birth weight in patients with gestational hypertension was found in 27 (30.34%) patients. Conclusions: This study concluded that frequency of low birth weight in patients with gestational hypertension is very high.","PeriodicalId":45690,"journal":{"name":"Pakistan Journal of Medical & Health Sciences","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135037874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-30DOI: 10.54393/pjhs.v4i09.1039
Yasra Memon, Imran Ali Shaikh, Imran Karim
Proton pump inhibitor (PPI) is only acid blocking agent used for treating the disease known as gastroesophageal reflux (non-erosive), erosive esophagitis disease, dyspepsia disease and the peptic ulcer disease because of its efficacy and potency. However, overuse of it is examined an immediate result of absence of determination of need for steady treatment in many outdoor subjects Objective: To evaluate impact of proton pump inhibitor (PPI) on bone biochemistry in young individuals of Hyderabad. Methods: The study contained 227 young individuals of age 20-45 years, it was conducted in Liaquat University Hospital, Hyderabad City and Medicine OPD’s of Jamshoro. The research study is undertaken using Quasi experimental study. The study duration is 6 months starting from 15th March 2020 to 15th September 2020 and sampling technique is non – probability convenience. SPSS 21 software is used to analyze the data. The post stratification chi – square test is performed at the interval of 95% confidence, besides it the P-value is observed ≤ 0.05. Results: There is no effect on serum calcium and vitamin D levels with use of proton pump inhibitor PPI. P-value was observed 0.7 for the serum calcium and the p- value for Serum Vitamin D was 0.1. Conclusions: Hence, the study showed that proton pump inhibitor PPI use for less than 6 months have no effect on bone biochemistry.
{"title":"Quasi Experimental Study to Ascertain Link of PPI to Bone Profile in Healthy Individuals","authors":"Yasra Memon, Imran Ali Shaikh, Imran Karim","doi":"10.54393/pjhs.v4i09.1039","DOIUrl":"https://doi.org/10.54393/pjhs.v4i09.1039","url":null,"abstract":"Proton pump inhibitor (PPI) is only acid blocking agent used for treating the disease known as gastroesophageal reflux (non-erosive), erosive esophagitis disease, dyspepsia disease and the peptic ulcer disease because of its efficacy and potency. However, overuse of it is examined an immediate result of absence of determination of need for steady treatment in many outdoor subjects Objective: To evaluate impact of proton pump inhibitor (PPI) on bone biochemistry in young individuals of Hyderabad. Methods: The study contained 227 young individuals of age 20-45 years, it was conducted in Liaquat University Hospital, Hyderabad City and Medicine OPD’s of Jamshoro. The research study is undertaken using Quasi experimental study. The study duration is 6 months starting from 15th March 2020 to 15th September 2020 and sampling technique is non – probability convenience. SPSS 21 software is used to analyze the data. The post stratification chi – square test is performed at the interval of 95% confidence, besides it the P-value is observed ≤ 0.05. Results: There is no effect on serum calcium and vitamin D levels with use of proton pump inhibitor PPI. P-value was observed 0.7 for the serum calcium and the p- value for Serum Vitamin D was 0.1. Conclusions: Hence, the study showed that proton pump inhibitor PPI use for less than 6 months have no effect on bone biochemistry.","PeriodicalId":45690,"journal":{"name":"Pakistan Journal of Medical & Health Sciences","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135038905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Ahmad Raza, Amna Sana, Laamia Altuf, Hajra Sultan, Rabia Parveen
Mostly in men, benign prostatic hyperplasia is serious issue. The volume of BPH increasing withurinary retention and is mostly determined by transabdominal sonography.Prostatic volumeinteractednegatively withhigh density lipoprotein cholesterol. Mostly occurrenceof BPHinmen with age of 45 to 60 years. BPH have lower urinary tract symptoms. About 20 recentpublicationssuitableforliteraturereviewwereretrievedfromdifferentdatabaseslikePubMed, sci.hub, and google scholar. The search on databases & search engines identified 27articles related to topic, among which only 20 articles were as per requirement. Only 20 articleswere usedfor extraction of data related to role of Abdominalultrasound todetectbenignprostatic hyperplasia. The current study looked at the detection of BPH with age. This review hasconclusionsthatultrasoundisamodalityofchoiceforevaluatingthepatientwithBPH,ithelpsin diagnosis as well as prediction of urinary retention and age has a significant factor in BPH.
{"title":"Role of Abdominal Ultrasound to Detect Benign Prostatic Hyperplasia with Significant Factor of Age","authors":"Muhammad Ahmad Raza, Amna Sana, Laamia Altuf, Hajra Sultan, Rabia Parveen","doi":"10.54393/pjhs.v4i09.978","DOIUrl":"https://doi.org/10.54393/pjhs.v4i09.978","url":null,"abstract":"Mostly in men, benign prostatic hyperplasia is serious issue. The volume of BPH increasing withurinary retention and is mostly determined by transabdominal sonography.Prostatic volumeinteractednegatively withhigh density lipoprotein cholesterol. Mostly occurrenceof BPHinmen with age of 45 to 60 years. BPH have lower urinary tract symptoms. About 20 recentpublicationssuitableforliteraturereviewwereretrievedfromdifferentdatabaseslikePubMed, sci.hub, and google scholar. The search on databases & search engines identified 27articles related to topic, among which only 20 articles were as per requirement. Only 20 articleswere usedfor extraction of data related to role of Abdominalultrasound todetectbenignprostatic hyperplasia. The current study looked at the detection of BPH with age. This review hasconclusionsthatultrasoundisamodalityofchoiceforevaluatingthepatientwithBPH,ithelpsin diagnosis as well as prediction of urinary retention and age has a significant factor in BPH.","PeriodicalId":45690,"journal":{"name":"Pakistan Journal of Medical & Health Sciences","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135038352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Insomnia is increasing day by day, according to global prevalence it ranges from10%to40%with trouble falling asleep, remaining asleep, or having non-restorative sleep that is accompanied by daytime impairment or distress. Magnesium seems to play a key role in there gelation of sleep. Objective: To compare the therapeutic effect of magnesium supplementation in improving quality of life among elderly insomniac participants with control and treatment group. Methods: The study design was double blind randomized clinical trial. Purposive sampling technique was used to allocate gender elderly people. Data were collected from Al-Saida Shuhda old age home, Lahore and the participants were divided into two groups, 40 participants in each group. Group 0 (control group) were given regular diet without magnesium supplement for 8 weeks. Group 1 (treatment group were given Magnesium supplements (500mg) for 8 weeks. Data were tabulated and analyzed with the help of SPSS 25.0. Results: The results shown that the magnesium supplementation had highly significant results in improving LSEQ, serum magnesium, serum melatonin, serum cortisol and serum renin level without showing any side effects. Group 0 has shown 0.152 (GTS), 0.088(QOS), 0.168(AFS), 0.195(BFW), 0.292(serum Mg), 0.567(serum melatonin), 0.276(serum cortisol), 0.101(serum renin) whereas group 1 has shown 0.01(GTS), 0.01(QOS), 0.003(AFS) and 0.03(BFW), 0.02(serum Mg), 0.01(serum melatonin), 0.02(serum cortisol), 0.02(serum renin), respectively. Conclusions: It was concluded from the results that magnesium supplementation in elderly people has highly significant effects in improving insomnia and quality of sleep.
{"title":"Therapeutic Effect of Magnesium Supplementation in Improving Quality of Life among Elderly Insomniac Participants","authors":"Amna Liaqat, Bahisht Rizwan, Ayesha Amjad, Zunaira Rasool","doi":"10.54393/pjhs.v4i09.995","DOIUrl":"https://doi.org/10.54393/pjhs.v4i09.995","url":null,"abstract":"Insomnia is increasing day by day, according to global prevalence it ranges from10%to40%with trouble falling asleep, remaining asleep, or having non-restorative sleep that is accompanied by daytime impairment or distress. Magnesium seems to play a key role in there gelation of sleep. Objective: To compare the therapeutic effect of magnesium supplementation in improving quality of life among elderly insomniac participants with control and treatment group. Methods: The study design was double blind randomized clinical trial. Purposive sampling technique was used to allocate gender elderly people. Data were collected from Al-Saida Shuhda old age home, Lahore and the participants were divided into two groups, 40 participants in each group. Group 0 (control group) were given regular diet without magnesium supplement for 8 weeks. Group 1 (treatment group were given Magnesium supplements (500mg) for 8 weeks. Data were tabulated and analyzed with the help of SPSS 25.0. Results: The results shown that the magnesium supplementation had highly significant results in improving LSEQ, serum magnesium, serum melatonin, serum cortisol and serum renin level without showing any side effects. Group 0 has shown 0.152 (GTS), 0.088(QOS), 0.168(AFS), 0.195(BFW), 0.292(serum Mg), 0.567(serum melatonin), 0.276(serum cortisol), 0.101(serum renin) whereas group 1 has shown 0.01(GTS), 0.01(QOS), 0.003(AFS) and 0.03(BFW), 0.02(serum Mg), 0.01(serum melatonin), 0.02(serum cortisol), 0.02(serum renin), respectively. Conclusions: It was concluded from the results that magnesium supplementation in elderly people has highly significant effects in improving insomnia and quality of sleep.","PeriodicalId":45690,"journal":{"name":"Pakistan Journal of Medical & Health Sciences","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135038357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cerebral palsy refers to a non-progressive brain disorder that affects the development of brain in developing infant and reduces the quality of life. Quality of life (QOL) is assessed using the CPQOL tool. Objectives: To assess the quality of life of children with CP. Methods: A cross-sectional study was conducted at the National Institute of Rehabilitation Medicine, Islamabad during Oct-2022 to Mar-2023. The sample was raised using slovin’s formula and non-probability convenient sampling technique was used. Data were collected using standard CP-QOL tool. All types of CP diagnosed cases both gender, presence of a caregiver and an age range of 4 to 12 years were included. Patients with non-availability of a caregiver and presence of any other illness not associated with CP were excluded. Results: Out of 129 participants, 105 were included on the basis of inclusion and exclusion criteria. The mean ± SD of patients overall score came out to be 46.83 ±9.75. CPQOL score of males were 47.36±9.96 and of female was 46.19±9.56. CPQOL score of age 4-6years was 45.12±10.58, 7-9 years was 47.70±9.15 and 10-12 years was 49.21±8.54 while overall CPQOL score of children with diplegic CP was 48.38±9.11, hemiplegic CP was 48.66±7.74, quadriplegic CP was 37.92±11.16. Conclusions: study showed that among both genders, females had poor QoL than males. This study also concluded that quadriplegic children had poor QoL than any other types of cerebral palsy. The overall status of QoL of children having Cerebral Palsy was low.
{"title":"Quality of life in Children with Cerebral Palsy","authors":"Sidra Hanif, Arooj Zameer, Hamra Waheed, Faryal Zaidi, Ishaq Ahmed, Maham Choudary","doi":"10.54393/pjhs.v4i09.1042","DOIUrl":"https://doi.org/10.54393/pjhs.v4i09.1042","url":null,"abstract":"Cerebral palsy refers to a non-progressive brain disorder that affects the development of brain in developing infant and reduces the quality of life. Quality of life (QOL) is assessed using the CPQOL tool. Objectives: To assess the quality of life of children with CP. Methods: A cross-sectional study was conducted at the National Institute of Rehabilitation Medicine, Islamabad during Oct-2022 to Mar-2023. The sample was raised using slovin’s formula and non-probability convenient sampling technique was used. Data were collected using standard CP-QOL tool. All types of CP diagnosed cases both gender, presence of a caregiver and an age range of 4 to 12 years were included. Patients with non-availability of a caregiver and presence of any other illness not associated with CP were excluded. Results: Out of 129 participants, 105 were included on the basis of inclusion and exclusion criteria. The mean ± SD of patients overall score came out to be 46.83 ±9.75. CPQOL score of males were 47.36±9.96 and of female was 46.19±9.56. CPQOL score of age 4-6years was 45.12±10.58, 7-9 years was 47.70±9.15 and 10-12 years was 49.21±8.54 while overall CPQOL score of children with diplegic CP was 48.38±9.11, hemiplegic CP was 48.66±7.74, quadriplegic CP was 37.92±11.16. Conclusions: study showed that among both genders, females had poor QoL than males. This study also concluded that quadriplegic children had poor QoL than any other types of cerebral palsy. The overall status of QoL of children having Cerebral Palsy was low.","PeriodicalId":45690,"journal":{"name":"Pakistan Journal of Medical & Health Sciences","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135037873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-30DOI: 10.54393/pjhs.v4i09.1007
Feriha Fatima Khidri, Hina Riaz, Yar Muhammad Waryah, Roohi Nigar, Ali Muhammad Waryah
Factor V Leiden (FVL) mutation is related to venous thromboembolism and pregnancy complications. It is highly prevalent among Caucasians; however, few studies have been conducted on the Asian population. Objective: To find the prevalence, genotype, and allelic frequency of FVL mutation in females of Sindh, Pakistan, and to develop a valid and economical method for the detection of FVL mutation in resource-limited settings. Methods: Hundred (n=100), unrelated healthy females of Sindh, Pakistan, were recruited. FVL was detected using three methods, i.e., tetra primer amplification refractory mutation system (ARMS)-polymerase chain reaction (PCR), PCR-restriction fragment length polymorphism (PCR-RFLP), and PCR-sequencing. Prevalence, genotype, and allele frequencies were calculated. We compared the three mutation detection methods to find a suitable protocol for FVL detection in developing countries. Results: The prevalence of FVL mutation was 3% in healthy females of Sindh, Pakistan. No homozygous FVL mutation was found. The results from tetra primer ARMS-PCR, PCR-RFLP, and PCR-sequencing were 100% concordant. Tetra primer ARMS-PCR was a valid, reliable, faster, economical genotyping and screening method. Conclusions: In conclusion, FVL mutation was found in our population, and further studies should be conducted to find its role in thromboembolic and obstetrical complications. In addition, we have suggested tetra primer ARMS-PCR as an appropriate method for FVL detection in resource-limited settings.
{"title":"Prevalence of Factor V Leiden Mutation in Healthy Females of Sindh, Pakistan and Comparison of Three Detection Methods in Resource-Limited Settings","authors":"Feriha Fatima Khidri, Hina Riaz, Yar Muhammad Waryah, Roohi Nigar, Ali Muhammad Waryah","doi":"10.54393/pjhs.v4i09.1007","DOIUrl":"https://doi.org/10.54393/pjhs.v4i09.1007","url":null,"abstract":"Factor V Leiden (FVL) mutation is related to venous thromboembolism and pregnancy complications. It is highly prevalent among Caucasians; however, few studies have been conducted on the Asian population. Objective: To find the prevalence, genotype, and allelic frequency of FVL mutation in females of Sindh, Pakistan, and to develop a valid and economical method for the detection of FVL mutation in resource-limited settings. Methods: Hundred (n=100), unrelated healthy females of Sindh, Pakistan, were recruited. FVL was detected using three methods, i.e., tetra primer amplification refractory mutation system (ARMS)-polymerase chain reaction (PCR), PCR-restriction fragment length polymorphism (PCR-RFLP), and PCR-sequencing. Prevalence, genotype, and allele frequencies were calculated. We compared the three mutation detection methods to find a suitable protocol for FVL detection in developing countries. Results: The prevalence of FVL mutation was 3% in healthy females of Sindh, Pakistan. No homozygous FVL mutation was found. The results from tetra primer ARMS-PCR, PCR-RFLP, and PCR-sequencing were 100% concordant. Tetra primer ARMS-PCR was a valid, reliable, faster, economical genotyping and screening method. Conclusions: In conclusion, FVL mutation was found in our population, and further studies should be conducted to find its role in thromboembolic and obstetrical complications. In addition, we have suggested tetra primer ARMS-PCR as an appropriate method for FVL detection in resource-limited settings.","PeriodicalId":45690,"journal":{"name":"Pakistan Journal of Medical & Health Sciences","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135038356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：