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Pharmacotherapy in Cardiovascular Disease with Chronic Kidney Disease Medications: A Comprehensive Literature 心血管疾病与慢性肾脏疾病药物的药物治疗:综合文献
Q4 Medicine Pub Date : 2023-09-30 DOI: 10.54393/pjhs.v4i09.1021
Maryam Azhar, Muneeb Zafar, Ali Irtaza, Madiha Asad, Sajal Kim, Manam Walait, Huda Rehman Mir, Salman Walyat
A progressive decrease of renal function is a symptom of chronic kidney disease, commonly known as chronic kidney failure. The body may accumulate hazardous amounts of fluid, electrolytes, and wastes if the patient has advanced chronic kidney disease. There are several causative factors which lead to CKD which include high or low blood pressure, more accumulation of cholesterol, diabetes and many more. According to WHO global health statistics in 2012, 864,226 mortalities (or 15% of all deaths worldwide) were attributed to this illness. CKD was categorized 14th on the index of principal causes of death, having 122 mortalities per 100,000 persons. Most of the causes of deaths were due to sudden cardiac arrests in CKD patients. In this review, we made a list of 10 FDA approved medications which has proven to decrease CKD and fatalities caused by cardiac arrests. SGLT-2 inhibitors have shown promising results in manipulating kidney functions to improve the efficiency of heart.
肾功能进行性下降是慢性肾脏疾病的一种症状,通常被称为慢性肾衰竭。如果患者患有晚期慢性肾脏疾病,身体可能会积聚有害数量的液体、电解质和废物。导致慢性肾病的原因有很多,包括高血压或低血压,胆固醇积累过多,糖尿病等等。根据世卫组织2012年全球卫生统计数据,有864 226例死亡(占全世界所有死亡人数的15%)归因于这种疾病。慢性肾病在主要死亡原因指数中排名第14,每10万人中有122人死亡。大多数死亡原因是由于CKD患者的心脏骤停。在这篇综述中,我们列出了10种FDA批准的药物,这些药物已被证明可以减少CKD和心脏骤停引起的死亡。SGLT-2抑制剂在操纵肾脏功能以提高心脏效率方面显示出有希望的结果。
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引用次数: 0
Association between Poly Cystic Ovaries and Non-Alcoholic Fatty Liver Disease in Young Females on Ultrasonography 超声显示年轻女性多囊卵巢与非酒精性脂肪肝的关系
Q4 Medicine Pub Date : 2023-09-30 DOI: 10.54393/pjhs.v4i09.954
Tehreem Malik, Akash John, Abid Ali, Muhammad Ahmad Naeem
PCOS and nonalcoholic fatty liver disease are both associated with the metabolic syndrome, which is characterized by central adiposity, hypertension, diabetes, and dyslipidemia. Objective: To determine the association between poly cystic ovaries and non-alcoholic fatty liver disease in young females. Methods: In this cross-sectional study at Chughtai Medical Center in Lahore, 272 patients with polycystic ovaries and fatty liver disease were selected. Utilizing a convex abdominal instrument with a frequency range of 3-5 MHz, the Toshiba Nemio 17 was utilized. Results: In this study, 74 out of 272 female patients diagnosed with PCOS also had fatty liver, highlighting a significant association (p-value = 0.025). Notably, within the 17-25 age group, 45 to 46 patients exhibited fatty liver, suggesting a link between PCOS and fatty liver in younger individuals experiencing hormonal issues. Conclusions: This study demonstrates association between polycystic ovary syndrome in adolescent females and with nonalcoholic fatty liver disease. The findings support the notion that PCOS is more prevalent in individuals with NAFLD.
多囊卵巢综合征和非酒精性脂肪性肝病都与代谢综合征有关,代谢综合征的特征是中枢性肥胖、高血压、糖尿病和血脂异常。目的:探讨年轻女性多囊卵巢与非酒精性脂肪肝的关系。方法:选取拉合尔Chughtai医疗中心的272例多囊卵巢合并脂肪肝患者进行横断面研究。使用频率范围为3-5 MHz的凸腹部仪器,使用东芝Nemio 17。结果:在本研究中,272例诊断为PCOS的女性患者中有74例同时患有脂肪肝,两者之间存在显著相关性(p值= 0.025)。值得注意的是,在17-25岁年龄组中,45至46名患者表现出脂肪肝,这表明在经历激素问题的年轻人中,多囊卵巢综合征和脂肪肝之间存在联系。结论:本研究表明青春期女性多囊卵巢综合征与非酒精性脂肪性肝病之间存在关联。研究结果支持了PCOS在NAFLD患者中更为普遍的观点。
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引用次数: 0
Relationship between Patient’s Satisfaction and level of emotional Intelligence in Nurses Working in Tertiary Care Hospital 三级医院护士患者满意度与情绪智力水平的关系
Q4 Medicine Pub Date : 2023-09-30 DOI: 10.54393/pjhs.v4i09.968
Orung Zaib Masih, Madiha Mukhtar, Sarfraz Masih
Emotional intelligence is the ability to sense what is going on, to understand how it feels while in that circumstance, to effectively analyses and consider other people's thoughts and feelings, and to respond accordingly. It can be defined as the ability to correctly recognize one's own and others' emotions. Objectives: To determine the association between patients’ satisfaction and level of emotional intelligence (EI) in nurses working in medical and surgical department in tertiary care hospitals, Lahore. Methods: A correlational study design was used to carry on this study. This study was conducted at Mayo Hospital and Social Security Hospital Kot Lakh Pat Lahore. The duration of the study was six months from Jan, 2023 to June; 2023.The study participants were registered nurses (both male and female) and admit patients (both male and female) there. Purposive sampling technique was used n=265 participants were recruited. To assess the performance among nurses and patients, an observational checklist was used. Data of the study participants was entered in statistical software SPSS version 21.0 and was analyzed accordingly. Results: This study shows that there are statistically non-significant differences between patient’s satisfaction and emotional intelligence. The results revealed a non-significant association between nurses' emotional intelligence and patient’s satisfaction, as p-value is p=.381 which is non-significant. So, we reject the alternative hypothesis and accept the null hypothesis. Conclusions: It is concluded that nurse’s emotional intelligence has no relationship on patient’s satisfaction, Nurse’s emotional intelligence and its association with patient’s satisfaction, which results were non-significant.
情商是一种感知正在发生的事情的能力,能够理解在这种情况下的感受,能够有效地分析和考虑他人的想法和感受,并做出相应的反应。它可以被定义为正确识别自己和他人情绪的能力。目的:了解拉合尔三级医院内科和外科护士患者满意度与情绪智力水平的关系。方法:采用相关研究设计进行本研究。这项研究是在梅奥医院和社会保障医院进行的。研究时间为6个月,从2023年1月至6月;2023.研究参与者是注册护士(男性和女性),并在那里接收患者(男性和女性)。采用目的抽样方法,共招募265名参与者。为了评估护士和患者的表现,使用了观察性检查表。研究参与者的数据输入统计软件SPSS 21.0版本,并进行相应的分析。结果:本研究显示患者满意度与情绪智力的差异无统计学意义。结果显示,护士情绪智力与患者满意度之间的相关性不显著,p值为p=。381,这是不显著的。因此,我们拒绝备择假设,接受零假设。结论:护士情绪智力与患者满意度没有关系,护士情绪智力与患者满意度的关系不显著。
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引用次数: 0
Impact of Oral Vitamin D3 Supplementation on Quality of Life in Patients with Irritable Bowel Syndrome (IBS) 口服维生素D3对肠易激综合征(IBS)患者生活质量的影响
Q4 Medicine Pub Date : 2023-09-30 DOI: 10.54393/pjhs.v4i09.988
Anam Zubair, Bahisht Rizwan, Hooria Ajmal, Sahar Imran, Amsa Fatima
Irritable Bowel Syndrome (IBS) is the most prevailing complicated gastrointestinal disorder with an approximate 11.2% global prevalence, indicating a critical need for an improved understanding of the condition. Several studies suggested that adult IBS patients' symptoms and quality of life are markedly improved by vitamin D supplementation. Objective: To analyze the impact of oral Vitamin D3 supplementation on quality of life in patients with Intestinal Bowel Syndrome. Methods: A randomized control trial (RCT) was conducted for 9 months. Non-probability purposive sampling technique was used to allocate 24 participants aged between 25 to 35 years and BMI of 18–25. The participants were separated into two groups, G1 and G0. G1 received 50,000 IU of vitamin D weekly for 6 weeks. Results: Before the intervention, values of IBS-QOL for G1 were estimated as 1.8±0.71 while at the end of the intervention, there was a visible improvement in the values of IBS-QoL with the mean and SD determined as 2.4±0.51. The p-value for G1 was 0.002 which shows that there were significant improvements in the G1. Conclusions: The present study concluded that vitamin D supplementation can benefit patients with IBS by adding 5000 IU of vitamin D supplementation.
肠易激综合征(IBS)是最常见的复杂胃肠道疾病,全球患病率约为11.2%,这表明迫切需要提高对该疾病的了解。几项研究表明,补充维生素D可显著改善成年IBS患者的症状和生活质量。目的:分析口服维生素D3对肠道综合征患者生活质量的影响。方法:采用随机对照试验(RCT),为期9个月。采用非概率有目的抽样技术,对24名年龄在25 ~ 35岁,BMI在18 ~ 25岁之间的参与者进行抽样。参与者分为G1组和G0组。G1每周服用50,000 IU维生素D,持续6周。结果:干预前,G1期IBS-QOL值估计为1.8±0.71,干预结束时,IBS-QOL值有明显改善,平均值和标准差为2.4±0.51。G1组p值为0.002,G1组有明显改善。结论:本研究表明,补充5000 IU维生素D可使IBS患者受益。
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引用次数: 0
Application of Chitosan-Based Polysaccharide Biomaterials in Tissue Engineering 壳聚糖基多糖生物材料在组织工程中的应用
Q4 Medicine Pub Date : 2023-09-30 DOI: 10.54393/pjhs.v4i09.1038
Azeem Azam, Shumaila Ziafat, Ata ul Mustafa Fahid, Farhan Anjum, Hamza Faseeh, Rabia Bano, Attiq ur Rehman, Amina Bashir
Chitosan-based polysaccharide biomaterials have gained interest as viable options in tissue engineering due to their distinctive properties and wide range of potential applications. Biomaterials play a crucial role in regenerative medicine because they foster an environment conducive to cell growth and tissue repair. The chitin-derived polysaccharide chitosan is superior than synthetic materials in several ways: it has a similar structure to the extracellular matrix, is biocompatible, biodegradable, antimicrobial, and can incorporate bioactive chemicals. In this article, check how chitosan can be used in tissue engineering as a scaffold for different types of tissue, a hydrogel for wound healing, and a carrier for gene therapy, stem cell culture, and drug delivery. Scaffolds made from chitosan have shown tremendous promise in tissue engineering for the neurological system, bone and cartilage transplantation, and skin regeneration. Hydrogels made from chitosan have been shown to be useful in treating wounds and stopping bleeding. Chitosan's medicinal potential in gene therapy, stem cell culture, and targeted medication administration is further enhanced by the addition of bioactive components such as growth factors, genes, or medicines. In addition, using chitosan in tissue engineering can pave the way for future developments in stem cell techniques, nanotechnology, biofabrication, and 3D bioprinting, among other areas of study. These advances may one day lead to individualized and highly effective therapies for tissue repair and regeneration. The use of chitosan in tissue engineering has the potential to advance regenerative medicine and address the growing demand for more effective techniques to heal damaged tissues. Tissue engineers can revolutionize the field of regenerative medicine and enhance patient outcomes by taking use of chitosan's adaptability and bioactivity to create cutting-edge biomaterials and therapeutic techniques.
壳聚糖基多糖生物材料因其独特的性能和广泛的应用前景而成为组织工程领域的可行选择。生物材料在再生医学中起着至关重要的作用,因为它们营造了一个有利于细胞生长和组织修复的环境。甲壳素衍生的多糖壳聚糖在几个方面优于合成材料:它具有与细胞外基质相似的结构,具有生物相容性,可生物降解性,抗菌性,并且可以加入生物活性化学物质。在这篇文章中,看看壳聚糖如何在组织工程中用作不同类型组织的支架,伤口愈合的水凝胶,基因治疗的载体,干细胞培养和药物输送。壳聚糖制成的支架在神经系统、骨和软骨移植以及皮肤再生的组织工程中显示出巨大的前景。壳聚糖制成的水凝胶已被证明在治疗伤口和止血方面很有用。壳聚糖在基因治疗、干细胞培养和靶向药物管理方面的药用潜力通过添加生物活性成分(如生长因子、基因或药物)进一步增强。此外,在组织工程中使用壳聚糖可以为干细胞技术、纳米技术、生物制造和3D生物打印等其他研究领域的未来发展铺平道路。这些进步可能有一天会导致组织修复和再生的个性化和高效疗法。壳聚糖在组织工程中的应用有可能促进再生医学的发展,并解决日益增长的对更有效的修复受损组织技术的需求。组织工程师可以通过利用壳聚糖的适应性和生物活性来创造尖端的生物材料和治疗技术,从而彻底改变再生医学领域,提高患者的治疗效果。
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引用次数: 0
Oral Health Status of Health Care Workers in Tertiary Care Hospitals of Rawalpindi, Islamabad Pakistan 巴基斯坦伊斯兰堡拉瓦尔品第三级医院医护人员口腔健康状况调查
Q4 Medicine Pub Date : 2023-09-30 DOI: 10.54393/pjhs.v4i09.1040
Muhammad Farrukh Habib, Ayesha Pervaiz, Hassan Riaz, Humaira Mahmood, Jawaria Khan, Sher Afgan Raisani, Syed Ihtishaam Kakakhel, Nimra Riaz
Studies from all around the world have shown that healthcare professionals may encounter a number of obstacles to receiving dental care, which raises the prevalence of oral disorders in this population. In recent years, Pakistan has not done a national oral health assessment on the state of oral health among healthcare workers. Objective: To determine the oral health status of health care workers in tertiary care hospitals using Decayed, Missed, Filled tooth Index. Methods: Descriptive cross-sectional study was conducted utilizing a simple random selection and 385 healthcare workers between the ages of 20-50 years. Healthcare workers were assessed in tertiary care hospitals, and information on caries and gingival health was gathered. For the oral examination, the standards and procedures of the WHO were applied. Results: Only 9.8% of the respondents were healthy and mean DMFT score came out to be 3.28 ± 1.12. Conclusions: Healthcare workers in tertiary have unsatisfactory dental practices, poor attitude related to oral health and general lack of awareness about oral health.
来自世界各地的研究表明,卫生保健专业人员在接受牙科护理时可能会遇到许多障碍,这增加了这一人群中口腔疾病的患病率。近年来,巴基斯坦尚未对卫生保健工作者的口腔健康状况进行全国口腔健康评估。目的:利用龋缺补牙指数了解三级医院医护人员口腔健康状况。方法:采用简单随机抽样的方法,对385名年龄在20 ~ 50岁之间的卫生保健工作者进行描述性横断面研究。在三级保健医院对卫生保健工作者进行了评估,并收集了有关龋齿和牙龈健康的信息。口头审查采用了世界卫生组织的标准和程序。结果:健康者仅占9.8%,DMFT平均得分为3.28±1.12。结论:高校医护人员口腔卫生行为不理想,对口腔健康的态度较差,普遍缺乏口腔健康意识。
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引用次数: 0
Emerging role of MRI to assess the Volume of Pineal Glands in Schizophrenia and Mood Disorders: Literature Review MRI在评估精神分裂症和情绪障碍患者松果体体积中的新作用:文献综述
Q4 Medicine Pub Date : 2023-09-30 DOI: 10.54393/pjhs.v4i09.1027
Muhammad Ahmad Raza, Rabia Parveen, Hajra Sultan, Laamia Altuf, Amna Sana, Farwa Seemab Zafar
Most patients with manic depression and diseases have issues with their circadian rhythms and sleep. Melatonin, which is vital for circadian rhythm and sleep, is secreted by pineal gland. This study evaluated and compared the volume of pineal gland in individuals with psychotic symptoms and manic depression. The aim of study is to find out volume of Pineal glands in Schizophrenic Patients. The data included in this literature review were found using several search engines. Using magnetic resonance imaging, the total mean pineal volume compared with the total pineal gland volume of all patients. In this research's literature evaluation, only 26 articles were used for extraction of data related to topic statement. The current study looked role of MRI to assess volume of pineal gland in in Schizophrenic patients. Patients with manic depression had considerably lower mean volume of pineal gland than the other groups. It is concluded that although more research is needed to fully understand the aspects of medications and more mediating agents on the volume of pineal gland. This difference is not present in patients with manic depression. Pineal gland abnormalities in schizophrenia patients may contribute to the disease's etiology.
大多数躁狂抑郁症患者都有昼夜节律和睡眠问题。褪黑素是松果体分泌的,对昼夜节律和睡眠至关重要。本研究评估并比较了精神病症状和躁狂抑郁症患者的松果体体积。研究的目的是了解精神分裂症患者的松果体体积。本文献综述中的数据是通过几个搜索引擎找到的。采用磁共振成像技术,将所有患者的总平均松果体体积与总松果体体积进行比较。在本研究的文献评价中,仅使用了26篇文章来提取与主题陈述相关的数据。目前的研究探讨了核磁共振成像在评估精神分裂症患者松果体体积中的作用。躁狂抑郁症患者的平均松果体体积明显低于其他组。结论:虽然需要更多的研究来充分了解松果体体积的药物方面和更多的介导剂。这种差异在躁狂抑郁症患者中不存在。精神分裂症患者的松果体异常可能与该病的病因有关。
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引用次数: 0
A Comparative Study of Manual and Digital Methods and Stereopsis Assessment in Young Adults 手工与数字方法与青年人立体视觉评估的比较研究
Q4 Medicine Pub Date : 2023-09-30 DOI: 10.54393/pjhs.v4i09.1024
. Gul e Lala, Nashrah Imtiaz, Arsham Ikram, Anusha Sheraz, Qurat ul Ain, Sawera Ammad, Mawra Zahid
Reduced stereopsis or depth perception may be the early indicator of abnormal motor functions in people therefore, the stereopsis test is considered ideal for visual screening. It can accomplish the need for the assessment of stereopsis by using a cost-effective smartphone application. Objective: To compare the stereo acuity values of manual and digital stereopsis tests by using the Random Dot Stereo Acuity test with Lea Symbols (Manual) and the SAT App for Android (Digital). Methods: A comparative cross-sectional study was carried out in the Eye department at The University of Lahore Teaching Hospital from February 2023 to May 2023. A total of 62 subjects aged 15-35 years were included in our study, out of which 31 were emmetropes and 31 were ametropes. Screening of subjects was done which included torch light examination and basic refraction. Manually stereopsis was measured using Random Dot stereo acuity test with Lea symbols and digitally it was measured by SAT application. Results: The mean ± SD stereo acuity value of the manual test (N=62) was 60.5242 ± 36.47607 seconds of arc and the mean stereo acuity value of the digital test (N=62) was 70.0968 ± 28.29569 seconds of arc. P-value was 0.006 which confirmed that our results were statistically significant. Conclusions: Our study highlighted the comparison of digital and manual stereopsis tests. We obtained different stereo acuity values from both tests on the same individuals. Hence, the manual test gave better values of stereopsis than the digital test.
立体视觉或深度感知能力下降可能是人类运动功能异常的早期指标,因此,立体视觉测试被认为是视觉筛查的理想选择。它可以通过使用具有成本效益的智能手机应用程序来完成对立体视觉评估的需要。目的:采用Lea Symbols (manual)和SAT App for Android (digital)进行随机点立体视敏度测试,比较手动立体视敏度和数字立体视敏度的差异。方法:于2023年2月至2023年5月在拉合尔大学教学医院眼科进行比较横断面研究。我们的研究共纳入了62名年龄在15-35岁之间的受试者,其中31名为正异性,31名为变异性。筛选受试者,包括火炬光检查和基本折射。人工立体视觉测量采用Lea符号随机点立体视敏度测试,数字立体视觉测量采用SAT软件。结果:手工测试(N=62)的平均±SD立体视敏值为60.5242±36.47607秒弧,数字测试(N=62)的平均立体视敏值为70.0968±28.29569秒弧。p值为0.006,证实我们的结果具有统计学意义。结论:我们的研究强调了数字和手动立体视觉测试的比较。我们从同一个体的两次测试中获得了不同的立体敏锐度值。因此,与数字测试相比,手动测试给出了更好的立体视觉值。
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引用次数: 0
Analysis of Serum Electrolytes Variation in Onset and Progression of Preeclampsia 子痫前期发病及发展过程中血清电解质变化分析
Q4 Medicine Pub Date : 2023-09-30 DOI: 10.54393/pjhs.v4i09.1047
Tamseela Mumtaz, Sania Shahid, Nageen Mustafa
Preeclampsia is one of the most common, life-threatening complications of pregnancy that is related to maternal as well as perinatal morbidity or mortality. One of the significant causes of preeclampsia is elevated blood pressure which is directly linked with concentrations of electrolytes in the blood. Objective: To evaluate the possible variations of electrolytes in preeclamptic pregnant females. Methods: A total of 90 pregnant females of 20 to 45 years of age were divided into three groups (n=30 in each group) viz normotensive, hypertensive, and preeclamptic pregnant females. All anthropometric and biophysical variables were measured. Among biochemical parameters, serum sodium, potassium, chloride, and calcium levels were determined using colorimetric assays while bicarbonate levels were determined by an enzymatic test using phosphoenolpyruvate carboxylase and a stable nicotinamide dihydrogen phosphate analogue. A comparison of serum electrolytes among different groups was executed by one-way analysis of variance. Results: Preeclamptic females had significantly higher BMI, and systolic and diastolic blood pressure than hypertensive and normotensive pregnant females (p<0.0001). Serum concentrations of sodium and calcium were significantly lower in preeclamptic pregnant females compared to hypertensive pregnant and normotensive pregnant females (p<0.0001). Conclusions: Alteration in the electrolyte levels may contribute to the onset and progression of preeclampsia. Nutritional sodium restriction along with adjuvant supplementation of Ca⁺⁺, Na⁺, K⁺, and Clˉ may minimize the risk of preeclampsia. On the basis of outcomes, it is recommended that pregnant females should eat a balanced diet that contains appropriate amounts of minerals micronutrients, and vitamins.
先兆子痫是妊娠期最常见的危及生命的并发症之一,与孕产妇及围产期发病率或死亡率有关。先兆子痫的一个重要原因是血压升高,这与血液中电解质的浓度直接相关。目的:探讨子痫前期孕妇体内电解质的变化。方法:将90例20 ~ 45岁的孕妇分为正常妊娠组、高血压妊娠组和子痫前期妊娠组,每组各30例。测量了所有人体测量和生物物理变量。在生化参数中,血清钠、钾、氯和钙水平采用比色法测定,而碳酸氢盐水平采用磷酸烯醇丙酮酸羧化酶和稳定的烟酰胺磷酸二氢类似物进行酶促试验测定。各组间血清电解质比较采用单因素方差分析。结果:子痫前期女性的BMI、收缩压和舒张压均明显高于高血压和正常妊娠女性(p<0.0001)。与高血压孕妇和正常孕妇相比,子痫前期孕妇的血清钠和钙浓度显著降低(p<0.0001)。结论:电解质水平的改变可能与子痫前期的发生和发展有关。限制营养钠并补充Ca +、Na +、K +和Cl +可以最大限度地降低子痫前期的风险。根据结果,建议孕妇应均衡饮食,含有适量的矿物质、微量元素和维生素。
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引用次数: 0
Global Health Security 全球卫生安全
Q4 Medicine Pub Date : 2023-09-30 DOI: 10.54393/pjhs.v4i09.1060
Riffat Mehboob
To reduce the risk and effect of sudden incidents of public health that put people at risk across national and international boundaries, it is necessary to take both preventive and reactive measures. These measures are referred to as global health security. Discussions on health security in scientific gatherings have become more prevalent in recent years after the Covid pandemic. Health security is for the whole world, irrespective of age, race, gender, or financial stability. However, it has been noted that there are many different concepts of health security, that the whole purpose of this is to accommodate only the upper-class societies. The disturbed equilibrium of the microbial world due to rapid urbanization, population increase, environmental deterioration, and the improper use of antimicrobials makes people realize the importance of health security that requires a collaborative approach focused on preparedness for any future pandemics and equal access to health care products. The covid-19 pandemic has had a great influence on people’s lives and their ability to think. Now the main race is not about defence systems; it has shifted towards more and better health security and the ability to deal with any future pandemics. The coronavirus outbreak was associated with severe acute respiratory syndrome, the Middle East respiratory syndrome coronavirus outbreak in 2012, the swine flu pandemic in 2009, and the West African Ebola virus disease epidemic in 2013–2016. All these epidemics are primarily caused by the significant travel of infected people across borders. This highlights the need for global health security, which helps coordinate surveillance and policymaking. This limits disease transmission and reduces the damage. While infectious diseases have no limits, inadequate health systems in poor nations make them worse and more out of control. Africa and other third-world states face many problems in securing global security. The spread of infectious diseases among susceptible areas is due to inadequate public healthcare fundings, vaccine coverage, poverty, armed conflict, and climate-related disasters, which damage developing countries. This only serves to increase susceptibility to the disease. The continuous transmission of polio and measles in different parts of Africa and Asia, as well as recent Ebola outbreaks in West Africa, highlights the need to overcome this in order to stop the spread of diseases to other areas. No nation can be completely protected from the spread of diseases due to a lack of social services and a strong health infrastructure; hence, global security demands global equality and progress towards health for everyone. To advance global health security in all nations, there is a need for multi-stakeholders and governance, justifiable finance through the proposed pandemic funds, and common goods for health. Future outbreaks can be efficiently managed by funding basic healthcare and enhancing the res
为了减少突发公共卫生事件的风险和影响,使人们面临跨越国家和国际边界的风险,有必要同时采取预防和反应措施。这些措施被称为全球卫生安全。近年来,在Covid大流行之后,科学聚会上关于卫生安全的讨论变得更加普遍。卫生安全属于全世界,不分年龄、种族、性别或财务稳定性。然而,人们注意到,卫生保障有许多不同的概念,其全部目的只是为了适应上层社会。由于快速城市化、人口增加、环境恶化和抗菌素使用不当,微生物世界的平衡受到破坏,这使人们认识到卫生安全的重要性,这需要采取协作方法,重点是为未来的任何大流行做好准备,并平等获得卫生保健产品。& # x0D;新冠肺炎疫情对人们的生活和思维能力产生了巨大影响。现在主要的竞赛不是关于防御系统;它已转向更多、更好的卫生安全和应对未来任何流行病的能力。此次冠状病毒疫情与2012年的严重急性呼吸综合征、2009年的猪流感大流行以及2013-2016年的西非埃博拉病毒病流行有关。所有这些流行病主要是由受感染者大量跨境旅行造成的。这突出了全球卫生安全的必要性,这有助于协调监测和决策。这限制了疾病的传播,减少了损害。虽然传染病没有限制,但贫穷国家不完善的卫生系统使它们变得更糟,更难以控制。非洲和其他第三世界国家在确保全球安全方面面临许多问题。传染病在易感地区的传播是由于公共保健资金不足、疫苗覆盖率低、贫困、武装冲突和与气候有关的灾害,这些都损害了发展中国家。这只会增加对这种疾病的易感性。小儿麻痹症和麻疹在非洲和亚洲不同地区的持续传播,以及最近西非爆发的埃博拉疫情,突出表明需要克服这一问题,以阻止疾病向其他地区蔓延。由于缺乏社会服务和强大的卫生基础设施,没有一个国家能够完全免受疾病传播的影响;因此,全球安全要求全球平等,并在人人享有健康方面取得进展。& # x0D;为了促进所有国家的全球卫生安全,需要多方利益攸关方和治理,需要通过拟议的大流行病基金提供合理的资金,需要卫生领域的共同利益。通过资助基本卫生保健和加强应对系统,可以有效地管理未来的疫情。大流行病防范和应对措施的公平性取决于不分肤色和性别的高级别政治承诺和全球领导。通过集中投资加强突发卫生事件基础设施,特别是通过初级卫生保健,可以消除国家之间的虚假矛盾,确保世界为处理复杂的突发公共卫生事件做好更好的准备。
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Pakistan Journal of Medical & Health Sciences
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