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WITHDRAWN: Neuroprotective Effect of 3,3′-Diindolylmethane and ɑ-Naphthoflavone, Aryl Hydrocarbon Receptor Modulators, in an Experimental Model of Ischemic Stroke 3,3'-二吲哚甲烷和ɑ-萘黄酮(芳香烃受体调节剂)在缺血性中风实验模型中的神经保护作用
IF 1.7 2区 文学 0 LANGUAGE & LINGUISTICS Pub Date : 2025-01-01 DOI: 10.2174/1871527321666220418120224
Neha Dhir, Ashish Jain, Amit Raj Sharma, Ajay Prakash, Alka Bhatia, Bikash Medhi

Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has been withdrawn.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham science disclaimer: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneouslysubmitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewheremust be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submittingthe article for publication the authors agree that the publishers have the legal right to take appropriate action against theauthors, if plagiarism or fabricated information is discovered. By submitting a manuscript the authors agree that the copyrightof their article is transferred to the publishers if and when the article is accepted for publication.

背景:芳基烃受体(AhR)介导的信号通路正在成为神经调节的靶点。本研究采用一过性大脑中动脉闭塞(MCAO)对 Wistar 大鼠进行脑卒中实验模型研究,旨在鉴定 AhR 调节剂(即 3,3'-diindolylmethane (DIM) 和 ɑ-naphthoflavone (ANF))的神经保护作用:方法:在 MCAO 发生 3 小时后,通过腹腔注射(i.p)相应的 AhR 调节剂对动物进行为期 4 天(间隔 24 小时)的治疗。一过性 MCAO 后,进行脑梗死体积、ND 评分和各种神经行为测试以确认缺血性中风。此外,还对氧化应激参数、炎症细胞因子和细胞凋亡 mRNA 表达进行了评估。使用 H&E 染色法评估大鼠大脑组织病理学变化,并将评估结果与分子参数进行关联:结果:AhR调节剂能显著减少MCAO后动物的脑梗塞体积和ND评分,并改善神经-精神障碍。AhR 配体治疗组的氧化应激、促炎细胞因子和细胞凋亡 mRNA 表达也明显减少。此外,还观察到治疗组在 MCAO 后神经元损伤方面有明显改善:结论:AhR通路调节可作为治疗急性缺血性中风(AIS)的重要治疗靶点。
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引用次数: 0
Encoding of nominal predication constructions: a typological investigation in verb-initial languages 名词谓语结构的编码:动词首语的类型学研究
2区 文学 0 LANGUAGE & LINGUISTICS Pub Date : 2023-11-06 DOI: 10.1515/lingty-2023-0035
Liwei Gong, Satoshi Uehara
Abstract Encoding of nominal predication constructions (NPC) is an essential component in typological debates concerning lexical flexibility and parts of speech. This study investigates encoding strategies of NPCs in 65 verb-initial languages from 20 language families. The results indicate that the combinations of a zero strategy and certain other typological features are cross-linguistically disfavored due to non-iconicity. The varying degree of lexical flexibility observed among languages reflects a competition between economy and iconicity, as in many other aspects of linguistic diversity.
名词谓语结构的编码是词汇灵活性和词性的类型学争论的重要组成部分。本研究对20个语系65种动词开头语言的npc编码策略进行了研究。结果表明,由于非象似性,零策略和某些类型特征的组合在跨语言上是不受欢迎的。语言之间不同程度的词汇灵活性反映了经济性和象似性之间的竞争,就像语言多样性的许多其他方面一样。
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引用次数: 0
Frontmatter 头版头条
2区 文学 0 LANGUAGE & LINGUISTICS Pub Date : 2023-10-01 DOI: 10.1515/lingty-2023-frontmatter3
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引用次数: 0
Grammar highlights 2022 2022年语法要闻
2区 文学 0 LANGUAGE & LINGUISTICS Pub Date : 2023-09-27 DOI: 10.1515/lingty-2023-2001
Jorge Emilio Rosés Labrada
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引用次数: 0
Specialization and finiteness (a)symmetry in imperative negation: with a comparison to standard negation 祈使否定的特殊性与有限性(a)对称性——与标准否定的比较
IF 2 2区 文学 0 LANGUAGE & LINGUISTICS Pub Date : 2023-08-04 DOI: 10.1515/lingty-2022-0007
Daniël Van Olmen [ˈdanijɛl vɑn ˈɔlmə]
Abstract This article focuses primarily on the claim in previous research that finiteness asymmetry occurs less often in imperative negation, due to its illocutionary dynamicity, than in standard negation, due to its stativity. Its secondary aim is to identify the languages suitable to test this hypothesis, with specialized imperatives as well as negative imperatives. The findings of this identification process in a balanced 200-language sample confirm the imperative and its negative counterpart as near-universal sentence types while simultaneously providing evidence for specialization asymmetry and thus for a certain mutual independence between the two. The results about finiteness asymmetry challenge the earlier claim: not only is finiteness asymmetry equally frequent in the two domains of negation; an explicit expression of illocutionary dynamicity can even give rise to it in imperative negation. In general, imperative negation’s finiteness asymmetry is found to be relatively unrelated to standard negation’s and not to be attributable to one single principle. The article shows that a variety of processes, such as grammaticalization and insubordination, are at work. They are argued to be motivated by the diachronic instability of negative imperatives, itself likely due to competing factors like politeness and negative reinforcement.
摘要:本文主要关注先前研究的结论,即祈使句否定由于其言外动态而比标准否定由于其静态而较少发生有限不对称。它的第二个目的是确定适合测试这一假设的语言,包括专门的祈使句和否定祈使句。在一个平衡的200种语言样本中,这一识别过程的发现证实了祈使句及其否定句是几乎普遍的句子类型,同时也为专业化不对称提供了证据,因此两者之间存在一定的相互独立性。关于有限不对称的结果挑战了先前的说法:有限不对称不仅在两个否定域中同样频繁;言外动态的显式表达甚至可以在祈使否定中产生言外动态。总的来说,祈使句否定的有限不对称与标准否定的有限不对称是相对无关的,也不是单一原则的结果。文章表明,各种各样的过程,如语法化和不服从,都在起作用。他们被认为是由消极命令的历时不稳定性所驱动的,而消极命令本身可能是由礼貌和负强化等竞争因素引起的。
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引用次数: 0
Current research in phonological typology. 语音类型学研究现状。
IF 1.7 2区 文学 0 LANGUAGE & LINGUISTICS Pub Date : 2023-07-26 Epub Date: 2023-02-01 DOI: 10.1515/lingty-2022-0069
Steven Moran, Shelece Easterday, Eitan Grossman
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引用次数: 0
Semantically negative adverbial clause-linkage: ‘let alone’ constructions, expletive negation, and theoretical implications 语义否定的副词分句连接:"别管 "结构、祈使句否定及理论意义
IF 2 2区 文学 0 LANGUAGE & LINGUISTICS Pub Date : 2023-07-24 DOI: 10.1515/lingty-2022-0066
Jesús he'sus olg'ɪn Olguín Martínez [mɑr'tinɛs]
Abstract One construction that has traditionally been neglected in the typological study of clause-linkage is that built on ‘let alone’ (e.g., the baby can’t even talk, let alone walk). The present study explores this construction in a convenience sample of 47 languages. There are languages in which ‘let alone’ clauses appear not only with a clause-linking device, but also with an optional standard negative marker. Moreover, there are languages in which standard negation is forbidden in the ‘let alone’ clause. Here it is shown that optional standard negation may be semantically empty or may have an expressive-evaluative layer of semantic interpretation. On the other hand, standard negation tends to be forbidden in ‘let alone’ clauses appearing with semantically monofunctional clause-linking devices. The paper further investigates whether the analysis advanced for ‘let alone’ clauses can be generalized to other semantically negative adverbial clauses: ‘without V-ing’, ‘instead of V-ing’, and ‘before’ clauses. It is demonstrated that in these latter adverbial clauses, standard negation may be forbidden or optional. Interestingly, unlike the situation with ‘let alone’ clauses, there are languages in which standard negation may be obligatory in the ‘without V-ing’, ‘instead of V-ing’, and ‘before’ clause. In this scenario, the adverbial relations are compositionally encoded by a standard negative marker together with a general marker.
摘要 在分句连接的类型学研究中,有一种构式历来被忽视,那就是以 "更不用说 "为基础的构式(例如,婴儿甚至不会说话,更不用说走路了)。本研究以 47 种语言为样本,对这种结构进行了探讨。在这些语言中,"let alone "分句不仅带有分句连接装置,而且还带有可选的标准否定标记。此外,还有一些语言禁止在 "let alone "从句中使用标准否定。这里表明,可选的标准否定在语义上可能是空的,也可能具有语义解释的表达-评价层。另一方面,标准否定在 "let alone "句中往往是被禁止的,因为 "let alone "句中出现了语义上单一功能的分句连接装置。本文进一步研究了针对 "let alone "从句的分析是否可以推广到其他语义否定副词从句:"without V-ing"、"stead of V-ing "和 "before "从句。研究表明,在后一种副词从句中,标准否定可以是禁止的,也可以是可选的。有趣的是,与 "let alone "分句的情况不同,在有些语言中,"without V-ing"、"stead of V-ing "和 "before "分句中的标准否定可能是强制性的。在这种情况下,副词关系由一个标准否定标记和一个一般标记组成。
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引用次数: 0
Semantically negative adverbial clause-linkage: ‘let alone’ constructions, expletive negation, and theoretical implications 语义否定的副词分句连接:"别管 "结构、祈使句否定及理论意义
IF 2 2区 文学 0 LANGUAGE & LINGUISTICS Pub Date : 2023-07-24 DOI: 10.1515/lingty-2022-0066
Jesús Olguín Martínez
One construction that has traditionally been neglected in the typological study of clause-linkage is that built on ‘let alone’ (e.g., the baby can’t even talk, let alone walk). The present study explores this construction in a convenience sample of 47 languages. There are languages in which ‘let alone’ clauses appear not only with a clause-linking device, but also with an optional standard negative marker. Moreover, there are languages in which standard negation is forbidden in the ‘let alone’ clause. Here it is shown that optional standard negation may be semantically empty or may have an expressive-evaluative layer of semantic interpretation. On the other hand, standard negation tends to be forbidden in ‘let alone’ clauses appearing with semantically monofunctional clause-linking devices. The paper further investigates whether the analysis advanced for ‘let alone’ clauses can be generalized to other semantically negative adverbial clauses: ‘without V-ing’, ‘instead of V-ing’, and ‘before’ clauses. It is demonstrated that in these latter adverbial clauses, standard negation may be forbidden or optional. Interestingly, unlike the situation with ‘let alone’ clauses, there are languages in which standard negation may be obligatory in the ‘without V-ing’, ‘instead of V-ing’, and ‘before’ clause. In this scenario, the adverbial relations are compositionally encoded by a standard negative marker together with a general marker.
在分句连接的类型学研究中,有一种结构历来被忽视,那就是建立在 "更不用说 "基础上的结构(例如,婴儿甚至不会说话,更不用说走路了)。本研究以 47 种语言为样本,对这种结构进行了探讨。在这些语言中,'let alone'分句不仅带有分句连接装置,而且还带有可选的标准否定标记。此外,还有一些语言禁止在 "let alone "从句中使用标准否定。这里表明,可选的标准否定在语义上可能是空的,也可能具有语义解释的表达-评价层。另一方面,标准否定在 "let alone "句中往往是被禁止的,因为 "let alone "句中出现了语义上单一功能的分句连接装置。本文进一步研究了针对 "let alone "从句的分析是否可以推广到其他语义否定副词从句:"without V-ing"、"stead of V-ing "和 "before "从句。研究表明,在后一种副词从句中,标准否定可以是禁止的,也可以是可选的。有趣的是,与 "let alone "分句的情况不同,在有些语言中,"without V-ing"、"stead of V-ing "和 "before "分句中的标准否定可能是强制性的。在这种情况下,副词关系由一个标准否定标记和一个一般标记组成。
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引用次数: 0
Frontmatter 头版头条
2区 文学 0 LANGUAGE & LINGUISTICS Pub Date : 2023-07-01 DOI: 10.1515/lingty-2023-frontmatter2
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引用次数: 0
Review of Antipassive: typology, diachrony and related constructions 反被动语研究综述:类型、历时性及相关结构
2区 文学 0 LANGUAGE & LINGUISTICS Pub Date : 2023-05-26 DOI: 10.1515/lingty-2023-0006
Bettina Spreng
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引用次数: 0
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Linguistic Typology
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