首页 > 最新文献

Case Reports in Otolaryngology最新文献

英文 中文
Central Auditory Nervous System Stimulation through the Cochlear Implant Use and Its Behavioral Impacts: A Longitudinal Study of Case Series. 人工耳蜗对中枢听觉系统的刺激及其对行为的影响:一项病例系列的纵向研究。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-04-27 eCollection Date: 2021-01-01 DOI: 10.1155/2021/8888450
Marina Isabel Cavalcanti, Liliane Aparecida Fagundes Silva, Maria Valéria Schmidt Goffi Gomez, Tsuji Robinson Koji, Ricardo Ferreira Bento, Ana Cláudia Martinho de Carvalho, Matas Carla Gentile

The purpose of this study was to investigate, over a period of five years, the cortical maturation of the central auditory pathways and its impacts on the auditory and oral language development of children with effective use and without effective use of a Cochlear Implant (CI). A case series study was conducted with seven children who were CI users and seven children with normal hearing, with age- and gender-matched to CI users. The assessment was performed by long-latency auditory evoked potentials and auditory and oral language behavioral protocols. The results pronounced P1 latency decrease in all CI users in the first nine months. Over five years, five children with effective CI use presented decrease or stabilization of P1 latency and a gradual development of auditory and oral language skills, although, for most of the children, the electrophysiological and behavior results remained poor than their hearing peers' results. Two children who stopped the effective use of CI after the first year of activation had worsened auditory and oral language behavioral skills and presented increased P1 latency. A negative correlation was observed between behavioral measures and the P1 latency, the P1 component being considered an important clinical resource capable of measuring the cortical maturation and the behavioral evolution.

本研究的目的是在五年的时间里,调查有效使用和未有效使用人工耳蜗(CI)的儿童中枢听觉通路的皮层成熟及其对听觉和口语发展的影响。对7名CI使用者儿童和7名听力正常的儿童进行了病例系列研究,年龄和性别与CI使用者相匹配。评估采用长潜伏期听觉诱发电位和听觉和口头语言行为协议。结果表明,在前9个月里,所有CI用户的P1潜伏期都有所下降。在5年的时间里,5名使用有效CI的儿童表现出P1潜伏期减少或稳定,听觉和口语技能逐渐发展,尽管对大多数儿童来说,电生理和行为结果仍然比他们的听力同龄人差。两名在激活一年后停止有效使用CI的儿童听觉和口语行为技能恶化,P1潜伏期增加。行为测量与P1潜伏期呈负相关,P1成分被认为是能够测量皮层成熟和行为演变的重要临床资源。
{"title":"Central Auditory Nervous System Stimulation through the Cochlear Implant Use and Its Behavioral Impacts: A Longitudinal Study of Case Series.","authors":"Marina Isabel Cavalcanti,&nbsp;Liliane Aparecida Fagundes Silva,&nbsp;Maria Valéria Schmidt Goffi Gomez,&nbsp;Tsuji Robinson Koji,&nbsp;Ricardo Ferreira Bento,&nbsp;Ana Cláudia Martinho de Carvalho,&nbsp;Matas Carla Gentile","doi":"10.1155/2021/8888450","DOIUrl":"https://doi.org/10.1155/2021/8888450","url":null,"abstract":"<p><p>The purpose of this study was to investigate, over a period of five years, the cortical maturation of the central auditory pathways and its impacts on the auditory and oral language development of children with effective use and without effective use of a Cochlear Implant (CI). A case series study was conducted with seven children who were CI users and seven children with normal hearing, with age- and gender-matched to CI users. The assessment was performed by long-latency auditory evoked potentials and auditory and oral language behavioral protocols. The results pronounced P1 latency decrease in all CI users in the first nine months. Over five years, five children with effective CI use presented decrease or stabilization of P1 latency and a gradual development of auditory and oral language skills, although, for most of the children, the electrophysiological and behavior results remained poor than their hearing peers' results. Two children who stopped the effective use of CI after the first year of activation had worsened auditory and oral language behavioral skills and presented increased P1 latency. A negative correlation was observed between behavioral measures and the P1 latency, the P1 component being considered an important clinical resource capable of measuring the cortical maturation and the behavioral evolution.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2021 ","pages":"8888450"},"PeriodicalIF":0.6,"publicationDate":"2021-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38988985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Granulomatosis with Polyangiitis as a Cause of Sudden-Onset Bilateral Sensorineural Hearing Loss: Case Report and Recommendations for Initial Assessment. 肉芽肿病合并多血管炎是突发性双侧感音神经性听力损失的原因:病例报告和初步评估的建议。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-04-20 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6632344
Paul R Ratmeyer, Benjamin R Johnson, Luis P Roldan, Tania L Kraai

Granulomatosis with polyangiitis (GPA) is a severe systemic vasculitis that commonly affects the paranasal sinuses, upper and lower respiratory tracts, and kidneys. GPA has also been associated with sensorineural hearing loss (SNHL), through inflammation of the cochlear apparatus. Early recognition, diagnostic laboratory evaluation, and appropriate treatment are essential to improve outcomes and achieve remission for patients with GPA. Here, we present a case of bilateral sudden sensorineural hearing loss (SSNHL) and distal symmetric polyneuropathy as the first presenting signs of GPA. A specific diagnostic work-up to rule out autoimmune inner-ear disease in patients with bilateral SSNHL is not clearly stated in the clinical practice guidelines from the American Academy of Otolaryngology-Head and Neck Surgery. The aim of this paper is to delineate an appropriate diagnostic work-up for patients with bilateral SSNHL when there is concern for autoimmune disease.

肉芽肿病伴多血管炎(GPA)是一种严重的全身性血管炎,通常影响副鼻窦、上、下呼吸道和肾脏。GPA也与耳蜗炎症引起的感音神经性听力损失(SNHL)有关。早期识别、诊断性实验室评估和适当的治疗对于改善GPA患者的预后和实现缓解至关重要。在此,我们报告一例双侧突发性感音神经性听力损失(SSNHL)和远端对称性多神经病变作为GPA的首发症状。美国耳鼻喉头颈外科学会的临床实践指南中没有明确规定排除双侧SSNHL患者自身免疫性内耳疾病的具体诊断检查。本文的目的是为双侧SSNHL患者描述一个适当的诊断检查,当有自身免疫性疾病的关注。
{"title":"Granulomatosis with Polyangiitis as a Cause of Sudden-Onset Bilateral Sensorineural Hearing Loss: Case Report and Recommendations for Initial Assessment.","authors":"Paul R Ratmeyer,&nbsp;Benjamin R Johnson,&nbsp;Luis P Roldan,&nbsp;Tania L Kraai","doi":"10.1155/2021/6632344","DOIUrl":"https://doi.org/10.1155/2021/6632344","url":null,"abstract":"<p><p>Granulomatosis with polyangiitis (GPA) is a severe systemic vasculitis that commonly affects the paranasal sinuses, upper and lower respiratory tracts, and kidneys. GPA has also been associated with sensorineural hearing loss (SNHL), through inflammation of the cochlear apparatus. Early recognition, diagnostic laboratory evaluation, and appropriate treatment are essential to improve outcomes and achieve remission for patients with GPA. Here, we present a case of bilateral sudden sensorineural hearing loss (SSNHL) and distal symmetric polyneuropathy as the first presenting signs of GPA. A specific diagnostic work-up to rule out autoimmune inner-ear disease in patients with bilateral SSNHL is not clearly stated in the clinical practice guidelines from the American Academy of Otolaryngology-Head and Neck Surgery. The aim of this paper is to delineate an appropriate diagnostic work-up for patients with bilateral SSNHL when there is concern for autoimmune disease.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2021 ","pages":"6632344"},"PeriodicalIF":0.6,"publicationDate":"2021-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38965213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to "A Case Report of Complete Resolution of Auricular Mucormycosis in an 18-Month-Old Diabetic Child". 18 个月大糖尿病患儿耳廓黏液瘤病完全治愈的病例报告》更正。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-04-17 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9794624
Mariam Aljehani, Hatem Alahmadi, Mansour Alshamani

[This corrects the article DOI: 10.1155/2021/6618191.].

[This corrects the article DOI: 10.1155/2021/6618191.].
{"title":"Corrigendum to \"A Case Report of Complete Resolution of Auricular Mucormycosis in an 18-Month-Old Diabetic Child\".","authors":"Mariam Aljehani, Hatem Alahmadi, Mansour Alshamani","doi":"10.1155/2021/9794624","DOIUrl":"10.1155/2021/9794624","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1155/2021/6618191.].</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2021 ","pages":"9794624"},"PeriodicalIF":0.6,"publicationDate":"2021-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38976194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to "A Case of Epistaxis as the First Sign of Acute Idiopathic Thrombocytopenic Purpura". “1例鼻出血是急性特发性血小板减少性紫癜的第一症状”的更正。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-04-12 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9804515
Shori Tajima, Fumihiko Matsumoto, Takashi Anzai, Satoshi Hara, Yo Suzuki, Katsuhisa Ikeda

[This corrects the article DOI: 10.1155/2021/6612939.].

[这更正了文章DOI: 10.1155/2021/6612939.]。
{"title":"Corrigendum to \"A Case of Epistaxis as the First Sign of Acute Idiopathic Thrombocytopenic Purpura\".","authors":"Shori Tajima,&nbsp;Fumihiko Matsumoto,&nbsp;Takashi Anzai,&nbsp;Satoshi Hara,&nbsp;Yo Suzuki,&nbsp;Katsuhisa Ikeda","doi":"10.1155/2021/9804515","DOIUrl":"https://doi.org/10.1155/2021/9804515","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1155/2021/6612939.].</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2021 ","pages":"9804515"},"PeriodicalIF":0.6,"publicationDate":"2021-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38954351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Aspiration Pneumonia Caused by Cerebrospinal Fluid Leaks Associated with Delayed Identification of Iatrogenic Skull Base Injury during Endoscopic Sinus Surgery. 内窥镜鼻窦手术中因脑脊液漏致吸入性肺炎伴医源性颅底损伤的延迟诊断1例。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-04-08 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5532194
Takashi Anzai, Akira Baba, Shin Ito, Yo Suzuki, Shori Tajima, Satoshi Hara, Yusuke Takata, Fumihiko Matsumoto, Katsuhisa Ikeda

Cerebrospinal fluid (CSF) leaks associated with endoscopic sinus surgery (ESS) are a rare complication affecting approximately 0.09% of patients. Although meningitis is a well-known complication of CSF leaks, the case we present is a rare and cautionary case of CSF leakage associated with ESS leading to aspiration pneumonia. A 43-year-old man with CSF leaks after ESS was referred to our hospital. After the operation, sometimes, he reported having a serous nasal discharge from the right side when he bent over, and he woke up choking on something every day. He also experienced headache, fever, fatigue, and cough. Interestingly, chest computed tomography (CT) showed a consolidation and ground-glass opacity in the posterior segments of the right upper lobes and superior segments of the bilateral lower lobes. These CT imaging findings were similar to those of aspiration pneumonia in bedridden patients who are always in a supine position. These findings suggest that CSF caused aspiration pneumonia. To the best of our knowledge, no case of aspiration pneumonia caused by CSF during endoscopic sinus surgery has been reported until now. If a patient with CSF leakage after ESS experiences fever, cough, or fatigue, physicians should consider aspiration pneumonia in addition to meningitis.

与内窥镜鼻窦手术(ESS)相关的脑脊液(CSF)泄漏是一种罕见的并发症,约占0.09%的患者。虽然脑膜炎是众所周知的脑脊液渗漏的并发症,我们提出的病例是一个罕见的和值得警惕的病例脑脊液渗漏与ESS导致吸入性肺炎。一名43岁男性因ESS后脑脊液渗漏被转介至我院。手术后,有时,他报告说,当他弯腰时,他有严重的右侧鼻分泌物,他每天醒来时都被什么东西噎住了。他还出现头痛、发烧、疲劳和咳嗽。有趣的是,胸部计算机断层扫描(CT)显示右上肺叶后段和双侧下肺叶上段有实变和磨玻璃影。这些CT影像表现与长期仰卧的卧床病人吸入性肺炎相似。这些结果提示CSF引起吸入性肺炎。据我们所知,目前尚未见鼻窦内窥镜手术中脑脊液引起吸入性肺炎的报道。如果ESS后出现脑脊液漏的患者出现发热、咳嗽或疲劳,除了脑膜炎外,医生还应考虑吸入性肺炎。
{"title":"A Case of Aspiration Pneumonia Caused by Cerebrospinal Fluid Leaks Associated with Delayed Identification of Iatrogenic Skull Base Injury during Endoscopic Sinus Surgery.","authors":"Takashi Anzai,&nbsp;Akira Baba,&nbsp;Shin Ito,&nbsp;Yo Suzuki,&nbsp;Shori Tajima,&nbsp;Satoshi Hara,&nbsp;Yusuke Takata,&nbsp;Fumihiko Matsumoto,&nbsp;Katsuhisa Ikeda","doi":"10.1155/2021/5532194","DOIUrl":"https://doi.org/10.1155/2021/5532194","url":null,"abstract":"<p><p>Cerebrospinal fluid (CSF) leaks associated with endoscopic sinus surgery (ESS) are a rare complication affecting approximately 0.09% of patients. Although meningitis is a well-known complication of CSF leaks, the case we present is a rare and cautionary case of CSF leakage associated with ESS leading to aspiration pneumonia. A 43-year-old man with CSF leaks after ESS was referred to our hospital. After the operation, sometimes, he reported having a serous nasal discharge from the right side when he bent over, and he woke up choking on something every day. He also experienced headache, fever, fatigue, and cough. Interestingly, chest computed tomography (CT) showed a consolidation and ground-glass opacity in the posterior segments of the right upper lobes and superior segments of the bilateral lower lobes. These CT imaging findings were similar to those of aspiration pneumonia in bedridden patients who are always in a supine position. These findings suggest that CSF caused aspiration pneumonia. To the best of our knowledge, no case of aspiration pneumonia caused by CSF during endoscopic sinus surgery has been reported until now. If a patient with CSF leakage after ESS experiences fever, cough, or fatigue, physicians should consider aspiration pneumonia in addition to meningitis.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2021 ","pages":"5532194"},"PeriodicalIF":0.6,"publicationDate":"2021-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38907845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Melanocytic Nevus in the External Auditory Canal with Keratin Accumulation. 外耳道黑色素细胞痣伴角蛋白积累。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-03-24 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5539286
Junhui Jeong, Kyuin Lee, Hyun Seung Choi

Nevus is a benign melanocytic neoplasm and the most common type of skin tumor. It may occur anywhere on the skin, but it is rare in the external auditory canal (EAC). We present a case of melanocytic nevus in the EAC with keratin accumulation. In microscopic surgery, the mass was excised completely, and the wax and keratin material medial portion of the EAC behind the mass was removed. In this patient, a melanocytic nevus in the EAC caused symptoms of hearing loss and wax and keratin buildup. For melanocytic nevus in the EAC, excision and pathologic confirmation should be performed if there are symptoms or when malignant transformation is suspected.

痣是一种良性黑色素细胞肿瘤,是最常见的皮肤肿瘤类型。它可能发生在皮肤的任何地方,但在外耳道(EAC)是罕见的。我们报告一例黑色素细胞痣在EAC与角蛋白积累。在显微手术中,肿块被完全切除,肿块后面EAC内侧部分的蜡和角蛋白物质被去除。在这个病人,黑素细胞痣在EAC引起听力丧失和蜡和角蛋白堆积的症状。对于EAC的黑素细胞痣,如有症状或怀疑恶性转化时,应行手术切除和病理证实。
{"title":"Melanocytic Nevus in the External Auditory Canal with Keratin Accumulation.","authors":"Junhui Jeong,&nbsp;Kyuin Lee,&nbsp;Hyun Seung Choi","doi":"10.1155/2021/5539286","DOIUrl":"https://doi.org/10.1155/2021/5539286","url":null,"abstract":"<p><p>Nevus is a benign melanocytic neoplasm and the most common type of skin tumor. It may occur anywhere on the skin, but it is rare in the external auditory canal (EAC). We present a case of melanocytic nevus in the EAC with keratin accumulation. In microscopic surgery, the mass was excised completely, and the wax and keratin material medial portion of the EAC behind the mass was removed. In this patient, a melanocytic nevus in the EAC caused symptoms of hearing loss and wax and keratin buildup. For melanocytic nevus in the EAC, excision and pathologic confirmation should be performed if there are symptoms or when malignant transformation is suspected.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2021 ","pages":"5539286"},"PeriodicalIF":0.6,"publicationDate":"2021-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25575734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concomitant Obstructive Sleep Apnoea in Patients with Meniere's Disease: A Case Report and Literature Review. 梅尼埃病患者伴发阻塞性睡眠呼吸暂停1例报告及文献复习
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-03-23 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5592611
Wong Kein Low, Esther Jiayi Lim

Meniere's disease (MD) is a condition characterised by fluctuating and progressive hearing loss, aural fullness, tinnitus, and intermittent attacks of vertigo. The disabling vertigo symptoms can be controlled in most patients by lifestyle changes and medications such as diuretics. Should standard medical therapy fail, the patient may require surgery in order to control the disease, but such surgical procedures can be functionally destructive. Obstructive sleep apnoea syndrome (OSAS) is common, especially in people who are grossly overweight. Up to 15% of patients with MD may have concomitant OSA. Unless the OSA is well controlled, such patients may continue to experience MD symptoms despite receiving adequate standard medical therapy for MD. Moreover, MD patients may experience insomnia as a result of vertigo and/or tinnitus where sedatives are indicated. The use of sedatives with muscle relaxant properties may inadvertently further aggravate OSA resulting in a vicious cycle of symptoms. Symptoms suggestive of concomitant OSA must be proactively sought as these patients do not necessarily exhibit the obvious phenotypic features of OSA. This is especially so in Asians where OSAS is commonly observed in people who are not overly obese. We report a case of a female patient who presented with recalcitrant MD disease and was later found to have concomitant OSA. The relevant literature will be reviewed, and learning points will be discussed from the perspective of the otologist/neurotologist. The clinician must always be mindful of the existence of concomitant "silent" OSAS as this impacts the management of patients with MD.

梅尼埃氏病(MD)是一种以波动和进行性听力丧失、听觉充盈、耳鸣和间歇性眩晕为特征的疾病。大多数患者的致残性眩晕症状可以通过改变生活方式和服用利尿剂等药物来控制。如果标准的药物治疗失败,患者可能需要手术来控制疾病,但这种手术可能会对功能造成破坏。阻塞性睡眠呼吸暂停综合征(OSAS)很常见,尤其是在严重超重的人群中。高达15%的MD患者可能伴有OSA。除非OSA得到很好的控制,否则尽管接受了适当的MD标准药物治疗,这些患者仍可能继续出现MD症状。此外,MD患者可能因眩晕和/或耳鸣而失眠,这时需要使用镇静剂。使用具有肌肉松弛特性的镇静剂可能会在无意中进一步加重OSA,导致症状的恶性循环。由于这些患者不一定表现出OSA的明显表型特征,因此必须积极寻找提示合并OSA的症状。这在亚洲尤其如此,在亚洲,OSAS通常出现在不过度肥胖的人群中。我们报告一例女性患者谁提出顽固性MD疾病,后来发现有合并阻塞性睡眠呼吸暂停。回顾相关文献,并从耳科/神经科医生的角度讨论学习要点。临床医生必须时刻注意伴随的“隐性”OSAS的存在,因为这会影响MD患者的管理。
{"title":"Concomitant Obstructive Sleep Apnoea in Patients with Meniere's Disease: A Case Report and Literature Review.","authors":"Wong Kein Low,&nbsp;Esther Jiayi Lim","doi":"10.1155/2021/5592611","DOIUrl":"https://doi.org/10.1155/2021/5592611","url":null,"abstract":"<p><p>Meniere's disease (MD) is a condition characterised by fluctuating and progressive hearing loss, aural fullness, tinnitus, and intermittent attacks of vertigo. The disabling vertigo symptoms can be controlled in most patients by lifestyle changes and medications such as diuretics. Should standard medical therapy fail, the patient may require surgery in order to control the disease, but such surgical procedures can be functionally destructive. Obstructive sleep apnoea syndrome (OSAS) is common, especially in people who are grossly overweight. Up to 15% of patients with MD may have concomitant OSA. Unless the OSA is well controlled, such patients may continue to experience MD symptoms despite receiving adequate standard medical therapy for MD. Moreover, MD patients may experience insomnia as a result of vertigo and/or tinnitus where sedatives are indicated. The use of sedatives with muscle relaxant properties may inadvertently further aggravate OSA resulting in a vicious cycle of symptoms. Symptoms suggestive of concomitant OSA must be proactively sought as these patients do not necessarily exhibit the obvious phenotypic features of OSA. This is especially so in Asians where OSAS is commonly observed in people who are not overly obese. We report a case of a female patient who presented with recalcitrant MD disease and was later found to have concomitant OSA. The relevant literature will be reviewed, and learning points will be discussed from the perspective of the otologist/neurotologist. The clinician must always be mindful of the existence of concomitant \"silent\" OSAS as this impacts the management of patients with MD.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2021 ","pages":"5592611"},"PeriodicalIF":0.6,"publicationDate":"2021-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38883916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Uncommon Cause of Dysphagia: Postpneumonectomy Syndrome. 吞咽困难的一个不常见原因:肺切除术后综合征。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-03-08 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6658690
Erica Rego, Ahmed Abdelmeguid, Yuqi Kevin Wang, Karuna Dewan

Objective: Dysphagia after pneumonectomy is uncommon but concerning. The purpose of this paper is to present a case of dysphonia secondary to postpneumonectomy syndrome. Case Report. A 66-year-old female with stage IIIa adenocarcinoma of the lung was treated with a left pneumonectomy. Three years later, she presented with severe dysphagia, dyspnea, and dysphonia. Esophagram demonstrated severely deviated esophagus to the left of midline, attributed to prior left-sided pneumonectomy, without clear evidence of any external compression. Chest CT scan showed associated leftward mediastinal shift. This patient was treated with voice therapy and an exclusion diet, as the patient elected not to have surgery.

Conclusion: This is the first reported case of dysphonia accompanying severe dysphagia following left pneumonectomy. While postpneumonectomy syndrome is rare, a high degree of clinical suspicion is recommended when treating patients with history of pneumonectomy.

目的:肺切除术后吞咽困难虽不常见,但值得关注。本文的目的是报告一个继发于肺切除术后综合征的发声障碍病例。病例报告。一例66岁女性IIIa期肺腺癌患者行左侧全肺切除术。三年后,她出现严重的吞咽困难、呼吸困难和发音困难。食管造影显示食管严重偏斜至中线左侧,归因于先前的左侧全肺切除术,无任何明显的外部压迫证据。胸部CT显示左侧纵隔移位。这名患者接受了语音治疗和排他饮食,因为患者选择不做手术。结论:这是首次报道的左侧全肺切除术后伴有严重吞咽困难的吞咽障碍病例。虽然肺切除术后综合征是罕见的,但在治疗有肺切除术史的患者时,建议高度怀疑。
{"title":"An Uncommon Cause of Dysphagia: Postpneumonectomy Syndrome.","authors":"Erica Rego,&nbsp;Ahmed Abdelmeguid,&nbsp;Yuqi Kevin Wang,&nbsp;Karuna Dewan","doi":"10.1155/2021/6658690","DOIUrl":"https://doi.org/10.1155/2021/6658690","url":null,"abstract":"<p><strong>Objective: </strong>Dysphagia after pneumonectomy is uncommon but concerning. The purpose of this paper is to present a case of dysphonia secondary to postpneumonectomy syndrome. <i>Case Report</i>. A 66-year-old female with stage IIIa adenocarcinoma of the lung was treated with a left pneumonectomy. Three years later, she presented with severe dysphagia, dyspnea, and dysphonia. Esophagram demonstrated severely deviated esophagus to the left of midline, attributed to prior left-sided pneumonectomy, without clear evidence of any external compression. Chest CT scan showed associated leftward mediastinal shift. This patient was treated with voice therapy and an exclusion diet, as the patient elected not to have surgery.</p><p><strong>Conclusion: </strong>This is the first reported case of dysphonia accompanying severe dysphagia following left pneumonectomy. While postpneumonectomy syndrome is rare, a high degree of clinical suspicion is recommended when treating patients with history of pneumonectomy.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2021 ","pages":"6658690"},"PeriodicalIF":0.6,"publicationDate":"2021-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25501563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Nasopharyngeal Carcinoma Ex Pleomorphic Adenoma: Case Report and Comprehensive Literature Review. 鼻咽癌多形性腺瘤1例报告及综合文献复习。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-02-26 eCollection Date: 2021-01-01 DOI: 10.1155/2021/8892280
Ellen L Tokarz, Adian A Ong, Mark S Burke

Carcinoma ex pleomorphic adenoma (CXPA) is an epithelial malignancy that transforms from benign pleomorphic adenomas (PA) at a rate of 1.5% after 5 years and 10% after 15 years. The average age of reported nasopharyngeal CXPA is 56.7 years. However, the present case describes a 19-year-old making this case exceptionally rare. Standard treatment is wide local excision with adjuvant treatment. We report the demographics, presentation, treatment, and outcomes of 8 cases of nasopharyngeal CXPA. While surgical excision is the mainstay of treatment, negative margins can be difficult to obtain at the skull base, and we report a recurrence rate of 50% in nasopharyngeal primaries. Due to the aggressive nature of the disease and high rate of recurrence, the majority of patients in our review received adjuvant radiation with some receiving adjuvant chemotherapy in addition.

癌前多形性腺瘤(CXPA)是一种由良性多形性腺瘤(PA)转变而来的上皮性恶性肿瘤,5年后发病率为1.5%,15年后发病率为10%。报告的鼻咽部CXPA的平均年龄为56.7岁。然而,本病例描述了一名19岁的患者,使得这种情况非常罕见。标准治疗是局部广泛切除配合辅助治疗。我们报告8例鼻咽炎的人口统计学、表现、治疗和结果。虽然手术切除是主要的治疗方法,但在颅底很难获得阴性切缘,我们报告鼻咽部原发的复发率为50%。由于疾病的侵袭性和高复发率,在我们的综述中,大多数患者接受辅助放疗,一些患者还接受辅助化疗。
{"title":"Nasopharyngeal Carcinoma Ex Pleomorphic Adenoma: Case Report and Comprehensive Literature Review.","authors":"Ellen L Tokarz,&nbsp;Adian A Ong,&nbsp;Mark S Burke","doi":"10.1155/2021/8892280","DOIUrl":"https://doi.org/10.1155/2021/8892280","url":null,"abstract":"<p><p>Carcinoma ex pleomorphic adenoma (CXPA) is an epithelial malignancy that transforms from benign pleomorphic adenomas (PA) at a rate of 1.5% after 5 years and 10% after 15 years. The average age of reported nasopharyngeal CXPA is 56.7 years. However, the present case describes a 19-year-old making this case exceptionally rare. Standard treatment is wide local excision with adjuvant treatment. We report the demographics, presentation, treatment, and outcomes of 8 cases of nasopharyngeal CXPA. While surgical excision is the mainstay of treatment, negative margins can be difficult to obtain at the skull base, and we report a recurrence rate of 50% in nasopharyngeal primaries. Due to the aggressive nature of the disease and high rate of recurrence, the majority of patients in our review received adjuvant radiation with some receiving adjuvant chemotherapy in addition.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2021 ","pages":"8892280"},"PeriodicalIF":0.6,"publicationDate":"2021-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25495762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exuberant Intratracheal Granuloma. 气管内大量肉芽肿。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-02-22 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6697478
Emelia Stuart, Michael Armaneous, David Bracken, Kayva Crawford, Andrew M Vahabzadeh-Hagh

Background: Upper airway granulomas are commonly encountered benign masses and are a result of pronounced tissue reactivity to localized respiratory mucosal trauma. The mechanism of injury to respiratory epithelium is most commonly iatrogenic and associated with intubation or indwelling tracheostomy. Case Report. A 40-year-old obese female with a history of multiple intubations, poorly controlled diabetes mellitus type II, and history of tracheal stenosis presented with sudden onset respiratory distress requiring intubation at an outside hospital. Direct laryngoscopy revealed a rapidly forming transglottic tissue mass, measuring 5.0 × 2.2 × 0.8 cm. The following case represents an unusual exception to our experience with granulomas given its rapidity of onset and migration of tissue around the endotracheal tube. Discussion. Laryngeal erythema and granulation formation are expected postintubation findings in most patients; however, the large size of granuloma tissue and rapid onset of symptoms in this case make it remarkable. Our patient had multiple risk factors for postintubation stenosis: female sex, poorly controlled diabetes, hypertension, obesity, and multiple prior intubations for periods lasting longer than forty-eight hours.

Conclusion: Our case highlights a rare laryngeal finding of a large granulation tissue mass causing sudden onset airway obstruction.

背景:上呼吸道肉芽肿是常见的良性肿块,是组织对局部呼吸道粘膜损伤的明显反应性的结果。呼吸道上皮损伤的机制通常是医源性的,与气管插管或留置气管切开术有关。病例报告。一名40岁肥胖女性,有多次插管史,控制不良的II型糖尿病,气管狭窄史,出现突发性呼吸窘迫,需要在医院外插管。直接喉镜检查发现快速形成的跨声门组织肿块,尺寸为5.0 × 2.2 × 0.8 cm。以下病例代表了我们对肉芽肿的一个不寻常的例外,因为它的发病速度快,气管内管周围的组织迁移。讨论。喉部红斑和肉芽形成是大多数患者插管后的预期结果;然而,在这种情况下,肉芽肿组织的大尺寸和快速发作的症状是值得注意的。我们的患者有多种插管后狭窄的危险因素:女性,控制不良的糖尿病,高血压,肥胖,多次插管持续时间超过48小时。结论:我们的病例突出了一个罕见的喉部发现,一个巨大的肉芽组织团块引起突发性气道阻塞。
{"title":"Exuberant Intratracheal Granuloma.","authors":"Emelia Stuart,&nbsp;Michael Armaneous,&nbsp;David Bracken,&nbsp;Kayva Crawford,&nbsp;Andrew M Vahabzadeh-Hagh","doi":"10.1155/2021/6697478","DOIUrl":"https://doi.org/10.1155/2021/6697478","url":null,"abstract":"<p><strong>Background: </strong>Upper airway granulomas are commonly encountered benign masses and are a result of pronounced tissue reactivity to localized respiratory mucosal trauma. The mechanism of injury to respiratory epithelium is most commonly iatrogenic and associated with intubation or indwelling tracheostomy. <i>Case Report</i>. A 40-year-old obese female with a history of multiple intubations, poorly controlled diabetes mellitus type II, and history of tracheal stenosis presented with sudden onset respiratory distress requiring intubation at an outside hospital. Direct laryngoscopy revealed a rapidly forming transglottic tissue mass, measuring 5.0 × 2.2 × 0.8 cm. The following case represents an unusual exception to our experience with granulomas given its rapidity of onset and migration of tissue around the endotracheal tube. Discussion. Laryngeal erythema and granulation formation are expected postintubation findings in most patients; however, the large size of granuloma tissue and rapid onset of symptoms in this case make it remarkable. Our patient had multiple risk factors for postintubation stenosis: female sex, poorly controlled diabetes, hypertension, obesity, and multiple prior intubations for periods lasting longer than forty-eight hours.</p><p><strong>Conclusion: </strong>Our case highlights a rare laryngeal finding of a large granulation tissue mass causing sudden onset airway obstruction.</p>","PeriodicalId":45872,"journal":{"name":"Case Reports in Otolaryngology","volume":"2021 ","pages":"6697478"},"PeriodicalIF":0.6,"publicationDate":"2021-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25452818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Case Reports in Otolaryngology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1