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Validation, performance, and reliability of two automated tests for vitamin B12 and folate assay. 维生素 B12 和叶酸测定的两种自动测试的验证、性能和可靠性。
IF 2.3 Q3 Medicine Pub Date : 2023-12-13 eCollection Date: 2023-10-01 DOI: 10.1177/22799036231217803
Simone Bianciardi, Giulia Tesi, Helena Cerutti, Alessandra Cartocci, Roberto Guerranti, Caterina Silvestrini, Sabrina Gori, Tommaso Bandini, Alessandra Brogi, Roberto Leoncini

Background: Deficiency of Vitamin B12 and folate may determine hematological, neurological, and metabolic alterations; therefore, an accurate quantification of their serum levels is required, especially in the presence of symptoms that might suggest a deficiency. CHORUS VIT B12 and CHORUS FOLATE are two automated immunoassays, developed to quantify vitamin B12 and folate, respectively, in human serum.

Design and methods: This single-center, non-pharmacological, diagnostic study described the validation and characterization of CHORUS VIT B12 and CHORUS FOLATE, with a specific focus on performance, precision, and reliability. For each assay, 500 serum samples were analyzed. A comparison between CHORUS assays and commercially available kit was also performed.

Results: For CHORUS VIT B12 the lower limit of quantification (LLoQ) was 165.0 pg/mL and the upper LoQ (ULoQ) was 1846.8 pg/mL. The assay was linear within the calibration range (150-2000 pg/mL) and the accuracy was described with the International Standard Vitamin B12, Serum Folate, HOLO TC (NIBSC code: 03/178), with a mean recovery on two lots of 111%. For CHORUS FOLATE (calibration range of 2.0-20.0 ng/mL), LLoQ was 2.0 ng/mL and ULoQ 19.6 ng/mL. The linearity was demonstrated from 2.4 to 20.0 ng/mL; the accuracy was described with the International Standard mentioned above, achieving a mean recovery on three lots of 92%. The lowest and highest values of both CHORUS and COBAS kits were similar and the median values did not significantly vary.

Conclusion: CHORUS VIT B12 and CHORUS FOLATE performed well, accurately, and reliably in quantifying vitamin B12 and folate in human serum.

背景:缺乏维生素 B12 和叶酸可能导致血液学、神经学和新陈代谢的改变;因此,需要对血清中的维生素 B12 和叶酸水平进行准确定量,尤其是在出现可能提示缺乏的症状时。CHORUS VIT B12 和 CHORUS FOLATE 是两种自动免疫测定法,分别用于定量检测人体血清中的维生素 B12 和叶酸:这项单中心、非药物性的诊断研究描述了 CHORUS VIT B12 和 CHORUS FOLATE 的验证和特征,重点关注其性能、精确度和可靠性。每种检测方法都分析了 500 份血清样本。此外,还对 CHORUS 检测试剂盒和市售试剂盒进行了比较:CHORUS VIT B12 的定量下限(LLoQ)为 165.0 pg/mL,定量上限(ULoQ)为 1846.8 pg/mL。该检测方法在校准范围(150-2000 pg/mL)内呈线性,准确度参照国际标准维生素 B12、血清叶酸、HOLO TC(NIBSC 代码:03/178),两个批次的平均回收率为 111%。对于叶酸钙(校准范围为 2.0-20.0 纳克/毫升),LLoQ 为 2.0 纳克/毫升,ULoQ 为 19.6 纳克/毫升。线性范围为 2.4 至 20.0 纳克/毫升;准确度参照了上述国际标准,三个批次的平均回收率为 92%。CHORUS和COBAS试剂盒的最低值和最高值相似,中位值没有显著差异:结论:CHORUS VIT B12 和 CHORUS FOLATE 在定量检测人体血清中的维生素 B12 和叶酸方面表现良好、准确、可靠。
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引用次数: 0
Development of an electronic medical records project for Al-Razi hospital in Palestine. 为巴勒斯坦Al-Razi医院制定电子医疗记录项目。
IF 2.3 Q3 Medicine Pub Date : 2023-12-04 eCollection Date: 2023-10-01 DOI: 10.1177/22799036231217795
Doaa Neirat, Ahmad Batran, Ahmad Ayed

Background: Electronic medical records (EMR) are considered an important aspect to improve medical services provided to patients. The purpose of this study was to assess the development of an Electronic Medical Records Project for Al-Razi hospital in Palestine.

Design and methods: The study was mixed method, qualitative and quantitative. The use of a questionnaire for the staff in the Al-Razi hospital and seven administrators' participants were meat as focus group.

Results: Approximately 136 participants in the study. The study findings reported that employees perceived the use of EMRs to have several benefits. The most common benefits include promoting patient safety culture and drug error reduction. In addition, the study findings reported that employees perceived the use of EMRs to have several challenges. The most common challenges include lack of knowledge and skill, insufficient time to use EMR, and limited of computers.

Conclusions: Health informatics brings various benefits to the healthcare system. Some participants believed that the EMR system would improve patient care and it will improve patient satisfaction.

背景:电子病历(EMR)被认为是改善医疗服务的一个重要方面。本研究的目的是评估巴勒斯坦Al-Razi医院电子病历项目的发展情况。设计与方法:采用定性与定量相结合的研究方法。对Al-Razi医院的工作人员和7名行政人员的参与者使用调查表作为焦点小组。结果:大约136名参与者参与了这项研究。研究结果显示,员工认为使用电子病历有几个好处。最常见的好处包括促进患者安全文化和减少药物错误。此外,研究结果显示,员工认为电子病历的使用存在一些挑战。最常见的挑战包括缺乏知识和技能,没有足够的时间使用电子病历,以及有限的计算机。结论:卫生信息学为卫生保健系统带来了多方面的好处。有嘉宾认为电子病历制度可以改善病人的护理,提高病人的满意度。
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引用次数: 0
Practical steps of intervention design for teenage students' musculoskeletal health: An intervention mapping approach. 青少年学生肌肉骨骼健康干预设计的实践步骤:干预测绘方法。
IF 2.3 Q3 Medicine Pub Date : 2023-11-30 eCollection Date: 2023-10-01 DOI: 10.1177/22799036231208354
Nazila NeJhaddadgar, Alireza Pirmoradi, Nafiseh Montazeri, Babak Nazari, Leila Rastgoo

Background: According to the studies conducted, teen pregnancy and its related health issues are among the most significant issues. The purpose of the study was to develop a musculoskeletal health intervention training programme using an intervention mapping approach (IMA) for teenagers aged 12-14 years old.

Methods: The present study is a study protocol where IMA has been used as a planning framework for developing a musculoskeletal health intervention training programme. Six steps of the intervention mapping process have been completed in the study. As the first step, needs assessment has been performed through systematic review and qualitative evaluation. In the second step, a matrix of change objectives was designed. Later on, after designing the programme and planning its implementation, the programme evaluation plan was developed.

Results: IMA guided us in designing and implementing a control-oriented training programme with the participation of the participants, along with the definition of outcomes, performance goals, and determinants, theoretical methods, practical applications, an intervention programme, implementation, and step-by-step assessment.

Conclusion: Intervention mapping is a participation-based approach to designing and implementing promotion programmes.

背景:根据所进行的研究,少女怀孕及其相关的健康问题是最重要的问题之一。这项研究的目的是为12-14岁的青少年制定一个使用干预测绘方法(IMA)的肌肉骨骼健康干预培训方案。方法:本研究是一项研究方案,IMA已被用作制定肌肉骨骼健康干预培训方案的规划框架。本研究完成了干预绘图过程的六个步骤。作为第一步,需求评估已经通过系统审查和定性评估进行。第二步,设计变更目标矩阵。后来,在设计方案并规划其实施之后,制定了方案评价计划。结果:IMA指导我们在参与者的参与下设计和实施了一个以控制为导向的培训计划,以及对结果、绩效目标和决定因素、理论方法、实际应用、干预计划、实施和逐步评估的定义。结论:干预绘图是设计和实施促进方案的一种基于参与的方法。
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引用次数: 0
Cost of maternal complications and its associated factors among mothers attending Hawassa public hospitals, Southern Ethiopia. 埃塞俄比亚南部阿瓦萨公立医院产妇并发症费用及其相关因素
IF 2.3 Q3 Medicine Pub Date : 2023-11-29 eCollection Date: 2023-10-01 DOI: 10.1177/22799036231215993
Dassalegn Loko, Angefa Ayele, Yadata Dessie, Behailu Hawulte, Gudeta Ayele, Tadesse Tolossa

Background: The cost of maternal complications is considered as an important factor hindering the utilization of maternal health care services. However, information of estimate of spending on maternal complication was lacking. This study was aimed to estimate the cost of maternal complications and associated factors among mother's attending Hawassa public hospitals, Sidama Regional state, Ethiopia.

Methods: A cross-sectional study design was conducted among 348 randomly selected mothers attending public hospitals in Hawassa from November 15 to December 15, 2021. Data was coded and entered into Epi Data version 3.1 and exported to STATA version 16.0 for analysis. Simple and multiple linear regression analysis was done. Correlation coefficient along with 95% CI was used to present the finding and p < 0.05 was used to declare statistical significance.

Results: This study found that total median cost of maternal complications was 4895.5 (IQR = 3779) ETB. The total median direct medical cost was 1765.5 (IQR = 1649.5) ETB. Number of days absent [(R = 0.028; 95% CI: (0.023, 0.033)], distance from facility [(R = 0.001; 95% CI: (0.000, 0.002)], site of laboratory diagnosis [(R = 0.230; 95% CI: (0.140, 0.320)], number of laboratory test conducted [(R = 0.045; 95% CI: (0.021, 0.069)] were found to be significance predictors of maternal complications costs.

Conclusions: Total median cost of maternal complications in current study was high. Respondents' site of diagnosis, number of days missed from work, number of laboratory tests, and distance from hospitals were independent predictors of maternal complications cost. Thus, we will recommend governments to introduce strategies that specifically help mothers with maternal complications.

背景:孕产妇并发症的费用被认为是阻碍孕产妇保健服务利用的重要因素。然而,缺乏估计用于产妇并发症的费用的资料。本研究的目的是估计在埃塞俄比亚西达马地区州哈瓦萨公立医院就诊的母亲的产妇并发症和相关因素的成本。方法:采用横断面研究设计,随机抽取2021年11月15日至12月15日在哈瓦萨公立医院就诊的348名母亲。将数据编码输入Epi Data 3.1版本,导出到STATA 16.0版本进行分析。进行了简单和多元线性回归分析。结果:本研究发现,产妇并发症的总中位成本为4895.5 (IQR = 3779) ETB。总直接医疗费用中位数为1765.5 (IQR = 1649.5) ETB。缺勤天数[R = 0.028;95% CI:(0.023, 0.033)],距离设施的距离[(R = 0.001;95% CI:(0.000, 0.002)],实验室诊断部位[(R = 0.230;95% CI:(0.140, 0.320)],实验室检测次数[(R = 0.045;95% CI:(0.021, 0.069)]是产妇并发症成本的显著预测因子。结论:本研究中产妇并发症的总中位成本较高。受访者的诊断地点、缺勤天数、实验室检查次数和离医院的距离是产妇并发症成本的独立预测因子。因此,我们将建议各国政府出台专门帮助患有产妇并发症的母亲的战略。
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引用次数: 0
The impact of the air pollution on health in New York City. 纽约市空气污染对健康的影响。
IF 2.3 Q3 Medicine Pub Date : 2023-11-29 eCollection Date: 2023-10-01 DOI: 10.1177/22799036231205870
Eugene S Mananga, Erika Lopez, Aissata Diop, Paulin Jt Dongomale, Fambougouri Diane

New York City is attempting to find a solution to an issue that many states and cities face: how to minimize air pollution so that it has fewer negative impacts on human health. Despite having the highest population in the United States (US), New York City typically has reasonably clean air. As the City and State of New York have worked to reduce emissions from local and regional sources, the air quality in New York City has improved during the past few decades. Despite these advancements, air pollution still poses a severe hazard to the health of everyone living in New York's environment. Various diseases including respiratory, circulatory, neurological, gastrointestinal, and urinary illnesses, which can be fatal, are intimately associated with air pollution. This review article will concentrate on how air pollution affects respiratory diseases such as asthma in children. In addition to analyzing the severe effects of air pollution on the vulnerable population, this review article will highlight the health repercussions of air pollution on New York City and its residents. furthermore, we argue for potential ideas and discoveries while also putting up a policy option to lower air pollution.

纽约市正试图为许多州和城市面临的一个问题找到解决方案:如何最大限度地减少空气污染,从而减少对人类健康的负面影响。尽管纽约是美国人口最多的城市,但它的空气却相当干净。随着纽约市和纽约州努力减少当地和区域的排放,纽约市的空气质量在过去几十年里得到了改善。尽管取得了这些进步,但空气污染仍然对生活在纽约环境中的每个人的健康构成严重危害。包括呼吸系统、循环系统、神经系统、胃肠道和泌尿系统疾病在内的各种致命疾病都与空气污染密切相关。这篇综述文章将集中讨论空气污染如何影响儿童哮喘等呼吸系统疾病。除了分析空气污染对弱势群体的严重影响外,这篇综述文章还将重点介绍空气污染对纽约市及其居民的健康影响。此外,我们讨论了潜在的想法和发现,同时也提出了降低空气污染的政策选择。
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引用次数: 0
How a low income state of India managed the unemployment situation during COVID-19? Lessons for future pandemic management. 作为低收入国家的印度如何应对2019冠状病毒病期间的失业状况?对未来大流行管理的教训。
IF 2.3 Q3 Medicine Pub Date : 2023-11-27 eCollection Date: 2023-10-01 DOI: 10.1177/22799036231208425
Sarit Kumar Rout, Ananda Meher, Pallavi Behera, Gatien de Broucker, Shridhar M Kadam

Background: The partial and complete lockdown to curb the spread of COVID-19 caused enormous economic and social disruptions throughout the world. India witnessed the sharpest decline in its Gross Domestic Product (GDP), and the unemployment rate rose sharply in the first quarter of 2020-21. Odisha, one of the low income states of India, has faced a steep rise in unemployment, with lakhs of migrant workers returning to the state. This article attempts to examine Odisha's unemployment situation compared to the low-income states of India as well as with the national average during COVID-19. This also investigates to what extent the Mahatma Gandhi National Rural Employment Guarantee Act (MGNREGA) provided relief to the people by providing short-term employment opportunities.

Design: This is a descriptive study and is based upon repetitive cross sectional secondary data on unemployment rate and labour force participation rate across the low-income states of India.

Method: The study used descriptive statistics to analyze the secondary data from the Center for Monitoring Indian Economy (CMIE) and MGNREGA report. The labour force participation rate (LFPR) and unemployment rate (UER) data were collected from the CMIE trimester reports. The information related to number days of employment demanded and employment provided were collected from the MGNREGA reports. Total time period was divided in to two parts - 2017-19 pre pandemic period and 2020-2021 pandemic period.

Results: The analysis of UER revealed that the unemployment situation in Odisha was better than the low-income states and overall India. The UER during COVID-19 (Sep-Dec 2020 to Sep-Dec 2021) was lower than the pre COVID-19 level in Odisha (1.6% in Sep-Dec 2020), compared to all India, where this was more than the pre-COVID-19 level (7.4% in Sep-Dec 2020). Odisha government had nearly doubled the employment generation through MGNREGA during 2020-21.The state government undertook a number of proactive measures - increasing wage rate, providing extra days of work in vulnerable districts to address the unemployment situation during the pandemic.

Conclusion: The state government's effort to manage the livelihood crisis was notable during the pandemic.. Proper implementation of the wage employment programmes led to higher decline in the UER in Odisha compared to other states These experiences can be emulated by other states or countries.

背景:为遏制新冠肺炎疫情传播而采取的部分和全面封锁措施,在全球范围内造成了巨大的经济和社会混乱。印度的国内生产总值(GDP)下降幅度最大,失业率在2020-21年第一季度大幅上升。奥里萨邦(Odisha)是印度的低收入邦之一,失业率急剧上升,成千上万的农民工返回该邦。本文试图将奥里萨邦的失业状况与印度低收入邦以及2019冠状病毒病期间的全国平均水平进行比较。本研究还调查了圣雄甘地国家农村就业保障法(MGNREGA)通过提供短期就业机会为人民提供救济的程度。设计:这是一项描述性研究,基于印度低收入邦失业率和劳动力参与率的重复横截面二手数据。方法:采用描述性统计方法,对来自印度经济监测中心(CMIE)和MGNREGA报告的二手数据进行分析。劳动力参与率(LFPR)和失业率(UER)数据收集自CMIE的三个月报告。有关要求就业和提供就业的天数的资料是从MGNREGA报告中收集的。总时间段分为两部分——2017- 2019年大流行前期和2020-2021年大流行期。结果:UER分析显示,奥里萨邦的失业状况好于低收入邦和整个印度。2019冠状病毒病期间(2020年9月至12月至2021年9月),奥里萨邦的UER低于2019冠状病毒病前的水平(2020年9月至12月为1.6%),而整个印度的UER高于2019冠状病毒病前的水平(2020年9月至12月为7.4%)。奥里萨邦政府在2020-21年期间通过MGNREGA创造的就业机会几乎翻了一番。州政府采取了一些积极措施——提高工资率,在脆弱地区提供额外的工作日,以解决大流行期间的失业问题。结论:疫情期间,邦政府在管理生计危机方面的努力值得注意。与其他邦相比,适当实施工资就业计划导致奥里萨邦的UER下降幅度更高。这些经验可以被其他邦或国家效仿。
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引用次数: 0
Self-efficacy in life skills and satisfaction among adolescents in school transitions. 转学青少年生活技能的自我效能感与满意度。
IF 2.3 Q3 Medicine Pub Date : 2023-11-24 eCollection Date: 2023-10-01 DOI: 10.1177/22799036231211420
Maria Luisa Pedditzi, Marcello Nonnis, Roberta Fadda

Background: Life skills, according to the World Health Organization, can promote youth well-being through educational school programs. Among life skills, decision-making and problem-solving skills can help adolescents consciously choose their career path.The Italian school system, in fact, requires students, already at a young age (13-14 years old) to make important decisions about their future, like for example choosing the high school that they would like to attend. This study aims to analyze differences in decision-making, self-efficacy, and life satisfaction in a sample of adolescents in secondary school in Italy. It aims to analyze whether there are differences in those dimensions according to students' age, gender, regularity, and future choice intentions.

Design and methods: Here we present a cross-sectional study involving 2104 students, balanced by gender, and attending upper secondary school in Italy. Participants completed Soresi and Nota's questionnaires on life satisfaction and Caprara's questionnaire on problem-solving self-efficacy. The data were processed using MANOVA.

Results: Research results show significant differences in self-efficacy and school satisfaction in relation to the age at which school transition occurred. Specifically, incoming preadolescents (13-14 years old) scored lower than outgoing late adolescents (17-18 years old) in both decision-making self-efficacy and school satisfaction. Girls scored lower than boys in decision-making self-efficacy. Students who expressed the intention to drop out of school scored lowest on both the self-efficacy and perceived support satisfaction scales.

Conclusions: The results highlight the importance of promoting the development of self-efficacy in life skills and school satisfaction to help students in school transitions.

背景:根据世界卫生组织的说法,生活技能可以通过教育学校项目促进青少年的福祉。在生活技能中,决策和解决问题的技能可以帮助青少年有意识地选择职业道路。事实上,意大利的学校系统要求学生在很小的时候(13-14岁)就对他们的未来做出重要的决定,比如选择他们想上的高中。本研究旨在分析意大利中学生在决策、自我效能和生活满意度方面的差异。本研究旨在分析学生的年龄、性别、规律性和未来选择意向在这些维度上是否存在差异。设计和方法:在这里,我们提出了一个横断面研究,涉及2104名学生,按性别平衡,在意大利上高中。参与者完成了Soresi和Nota的生活满意度问卷和Caprara的问题解决自我效能问卷。采用方差分析对数据进行处理。结果:研究结果显示,自我效能感和学校满意度与转学年龄有关。具体而言,在决策自我效能感和学校满意度方面,进入期前青少年(13-14岁)得分低于外向期晚期青少年(17-18岁)。女孩在决策自我效能方面的得分低于男孩。表现出退学意向的学生在自我效能感和感知支持满意度量表上得分最低。结论:本研究结果强调了促进生活技能自我效能感和学校满意度的发展对学生转学的重要性。
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引用次数: 0
'We are not here to enforce; we are here for the people' Factors influencing performance of contact tracing during the COVID-19 pandemic: A qualitative study. “我们不是来强制执行的;我们在这里是为了COVID-19大流行期间影响接触者追踪绩效的因素:一项定性研究。
IF 2.3 Q3 Medicine Pub Date : 2023-11-24 eCollection Date: 2023-10-01 DOI: 10.1177/22799036231208325
Fraukje Ef Mevissen, Babette van Deursen, Helene Acm Voeten, Anita Jcm Watzeels

Background: Provider-initiated contact tracing (CT) is an important measure to slow down the spread of infectious diseases such as COVID-19. However, carrying out effective CT depends on the collaboration between the patient and the contact tracer. To improve CT, it is important to understand which factors influence contact tracers in being able to carry out CT during large pandemics.

Methods: We performed individual semi-structured interviews with nine contact tracers working for the COVID-19 unit of the Public Health Service (PHS) Rotterdam-Rijnmond, the Netherlands, to explore their experiences with carrying out CT. Data were collected between July 2020 and December 2020. The interview protocol was structured based on the CT tasks and guided by the literature and the framework explaining adherence to clinical practice guidelines.

Results: In general, CT seemed to be carried out satisfactorily. Individual factors (interviewing techniques and skills, attitude towards the patient and attitude towards CT), factors related to the patient (cooperativeness and engagement, emotions, language and culture and (mis)information), guideline-related factors (characteristics) and factors related to the organisation (interactions with colleagues, support from management, workload and training) were found to influence the carrying out of CT.

Conclusion: To be well prepared for future pandemics, it is important to explore strategies that can be effective to support the contact tracer in performing CT, support patients in feeling comfortable to be engaged and ways to reach more consistency in policies and protocols.

背景:提供者发起的接触者追踪(CT)是减缓COVID-19等传染病传播的重要措施。然而,进行有效的CT取决于患者和接触追踪器之间的合作。为了改进CT,重要的是要了解哪些因素会影响接触示踪剂在大规模流行病期间进行CT的能力。方法:我们对荷兰鹿特丹-里恩蒙德公共卫生服务(PHS) COVID-19部门的9名接触者追踪者进行了单独的半结构化访谈,以探讨他们开展CT的经验。数据收集于2020年7月至2020年12月。访谈方案以CT任务为基础,并以文献和解释临床实践指南的框架为指导。结果:总体而言,CT检查结果令人满意。研究发现,个体因素(访谈技巧和技巧、对患者的态度和对CT的态度)、与患者相关的因素(合作和参与、情绪、语言和文化以及(错误)信息)、与指南相关的因素(特征)以及与组织相关的因素(与同事的互动、管理层的支持、工作量和培训)都会影响CT的开展。结论:为做好应对未来大流行的准备,探索有效支持接触者示踪器开展CT、支持患者安心参与、加强政策和方案一致性的策略十分重要。
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引用次数: 0
Modeling risk factors of degree of severity of Coronavirus disease 2019 (COVID-19) infection in inpatient patients at Dr. M. Djamil Padang. M. Djamil Padang博士医院住院患者2019冠状病毒病(COVID-19)感染严重程度的危险因素建模
IF 2.3 Q3 Medicine Pub Date : 2023-11-18 eCollection Date: 2023-10-01 DOI: 10.1177/22799036231204341
Masrizal, Ade Suzana Eka Putri, Nabila Putri Rahmatillah, Randy Novirsa, Muhammad Alfarezi

Background: RSUP Dr. M. Djamil was one of the COVID referral hospitals that treats patients with degrees of severity ranging from mild to critical. The high prevalence of COVID-19 differs from the severity of which it is necessary to know the risk factors as a preventive measure to minimize the higher risk. This study aims to determine the factors associated with the severity of COVID-19 in inpatients at Dr. M. Djamil Hospital, Padang, Indonesia.

Design and methods: A quantitative study with a cross-sectional design was conducted by reviewing the medical record data of COVID-19 inpatients from March 2020 to February 2021. Sampling using a simple random sampling technique with a total of 95 patients. The Prevalence Odds Ratio (POR) is a statistical measure used in epidemiology and medical research to assess the association between an exposure or risk factor and a particular outcome in a cross-sectional study.

Results: Based on research, there are 41 (43.2%) severe patients. There is a relationship between age with p-value 0.004 (POR 4.5; 95% CI; 1.48-12.1), cardiovascular disease with p-value 0.003 (POR 5.9; 95% CI 1.7-21.4), and respiratory disease with p-value 0.001 (POR 6.6; 95% CI; 2.1-20.8) against COVID-19 infection. Diabetes Mellitus is the confounding variable. Respiratory disease is the dominant factor associated with the severity of COVID-19. Respiratory disease has 6.6 POR or Prevalence Odds Ratio values which means that COVID-19 patients with respiratory disease 6.6 more severe than those who has not respiratory disease history.

Conclusions: Age, cardiovascular, and respiratory diseases are associated with the severity of COVID-19 infection in patients at Dr. M. Djamil Hospital, Padang, Indonesia. It is highly recommended to increase health promotion regarding risk factors for the severity of COVID-19 to the community to avoid a more severe outcome.

M. Djamil博士是治疗从轻度到危重程度患者的COVID转诊医院之一。COVID-19的高流行率与严重程度不同,因此有必要了解风险因素,以采取预防措施,将较高风险降至最低。本研究旨在确定与印度尼西亚巴东Dr. M. Djamil医院住院患者COVID-19严重程度相关的因素。设计与方法:采用横断面设计的定量研究方法,对2020年3月至2021年2月新冠肺炎住院患者的病历资料进行回顾性分析。抽样采用简单随机抽样技术,共95例患者。流行率优势比(POR)是流行病学和医学研究中用于评估暴露或风险因素与横断面研究中特定结果之间关系的统计度量。结果:经调查,重症患者41例(43.2%)。年龄与p值为0.004 (POR为4.5;95%可信区间;1.48-12.1),心血管疾病,p值为0.003 (POR为5.9;95% CI 1.7-21.4),呼吸系统疾病,p值为0.001 (POR为6.6;95%可信区间;2.1-20.8)预防COVID-19感染。糖尿病是混杂变量。呼吸系统疾病是与COVID-19严重程度相关的主要因素。呼吸道疾病的POR或患病率优势比为6.6,这意味着COVID-19呼吸道疾病患者比无呼吸道疾病病史的患者严重6.6。结论:印度尼西亚巴东Dr. M. Djamil医院患者的年龄、心血管和呼吸系统疾病与COVID-19感染的严重程度相关。强烈建议就COVID-19严重程度的危险因素加强对社区的健康促进,以避免更严重的结果。
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引用次数: 0
The impacts of electronic cigarette health warning labels on use intentions and perceptions: A cross-sectional study of US and Israeli adults who use tobacco. 电子烟健康警告标签对使用意图和认知的影响:对美国和以色列使用烟草的成年人的横断面研究。
IF 2.3 Q3 Medicine Pub Date : 2023-11-18 eCollection Date: 2023-10-01 DOI: 10.1177/22799036231214396
Zongshuan Duan, Hagai Levine, Yael Bar-Zeev, Yuxian Cui, Cassidy R LoParco, Yan Wang, Lorien C Abroms, Amal Khayat, Carla J Berg

Background: Health warning labels (HWLs) are evidence-based tobacco control strategies; however, their application to e-cigarettes and related impacts (e.g. on perceived risk), including across countries with different regulations, are understudied.

Design and methods: Using 2021 survey data from 927 US and Israeli adults reporting past-month tobacco use, multivariate analyses examined: (1) sociodemographics in relation to self-reported impact of e-cigarette HWLs (i.e. more concerned about e-cigarette use, reassured, no effect) among those who noticed e-cigarette HWLs (multinomial regressions); and (2) HWL impacts in relation to use intentions and perceived addictiveness and harm (linear regressions).

Results: Among those who noticed HWLs (n = 835, 90.1%), 34.1% reported HWLs resulted in greater concern about e-cigarette use, 45.5% no effect, and 20.4% reassurance. Factors associated with greater concern (vs no effect) included e-cigarette non-use (vs use; aOR = 1.69, 95% CI:1.22, 2.38), US (vs Israel) resident (aOR = 1.65, 95% CI:1.16, 2.34), age 18-25 (vs 36-45; aOR = 1.72, 95% CI:1.11, 2.67), and more education (aOR = 1.85, 95% CI:1.30, 2.63). Factors associated with being reassured (vs no effect) included use of cigarettes (aOR = 1.71, 95% CI:1.06, 2.75), e-cigarettes (aOR = 2.64, 95% CI:1.77, 3.94), and other tobacco (aOR = 2.11, 95% CI:1.39, 3.21), and Israeli resident (aOR = 2.33, 95% CI:1.47, 3.70). Not noticing HWLs (vs no effect) correlated with lower intentions (β = -0.44, 95% CI:-0.87, -0.01), perceived addictiveness (β = -0.61, 95% CI:-1.05, -0.18), and harm (β = -0.56, 95% CI:-0.95, -0.18); reassurance correlated with greater use intentions (β = 0.48, 95% CI:0.12, 0.83); and greater concern was unassociated with use intentions or perceived risk.

Conclusion: Effects of differing e-cigarette HWLs in distinct subpopulations warrant research. Despite being noticed, they may have no effect or encourage e-cigarette use.

背景:健康警示标签(HWLs)是循证控烟策略;然而,它们在电子烟中的应用及其相关影响(例如对感知风险的影响),包括在不同法规的国家之间的应用,尚未得到充分研究。设计和方法:使用来自927名美国和以色列成年人报告过去一个月烟草使用情况的2021年调查数据,多变量分析检查了:(1)注意到电子烟HWLs的人与自我报告的电子烟HWLs影响(即更关注电子烟使用,放心,没有影响)相关的社会人口统计学(多项回归);(2) HWL对使用意图、感知成瘾和伤害的影响(线性回归)。结果:在注意到HWLs的人中(n = 835, 90.1%), 34.1%的人报告HWLs导致对电子烟使用的更大担忧,45.5%的人没有影响,20.4%的人放心。与更大的担忧(vs无影响)相关的因素包括不使用电子烟(vs使用;aOR = 1.69, 95% CI:1.22, 2.38),美国(vs以色列)居民(aOR = 1.65, 95% CI:1.16, 2.34),年龄18-25岁(vs 36-45岁;aOR = 1.72, 95% CI:1.11, 2.67),以及更多的教育(aOR = 1.85, 95% CI:1.30, 2.63)。与安心(vs无影响)相关的因素包括吸烟(aOR = 1.71, 95% CI:1.06, 2.75)、电子烟(aOR = 2.64, 95% CI:1.77, 3.94)和其他烟草(aOR = 2.11, 95% CI:1.39, 3.21)和以色列居民(aOR = 2.33, 95% CI:1.47, 3.70)。不注意HWLs (vs无影响)与较低的意图(β = -0.44, 95% CI:-0.87, -0.01)、感知成瘾(β = -0.61, 95% CI:-1.05, -0.18)和伤害(β = -0.56, 95% CI:-0.95, -0.18)相关;安心与更大的使用意图相关(β = 0.48, 95% CI:0.12, 0.83);更大的担忧与使用意图或感知风险无关。结论:不同电子烟HWLs对不同亚人群的影响值得研究。尽管被注意到了,但它们可能没有影响或鼓励电子烟的使用。
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Journal of Public Health Research
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