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Challenging Behavior in Down Syndrome: Initial Surveys Evaluating Co-occurrence 唐氏综合症的挑战行为:评估共发生的初步调查
IF 1.1 Q3 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2023-05-31 DOI: 10.47611/jsr.v12i2.1942
M. Valdovinos
Down syndrome (DS) is a developmental disability caused by trisomy of chromosome 21 and as with other developmental disabilities, individuals with DS may present with challenging behavior (e.g., aggression, tantrums, self-injurious behavior; Feeley & Jones, 2006). The purpose of this study was to evaluate the presence of challenging behavior in those with DS by surveying caregivers of individuals with DS via Qualtrics. A link to our survey was sent out to national and local organizations that support the DS population with a request to disseminate the link. Given limited response, the survey was modified (shorted and reorganized) and a link to the revised survey was disseminated via Facebook to groups focused on DS. Although both surveys received limited responses, there are preliminary findings worth exploring further. Aggression, noncompliance, and tantrum behaviors were frequently reported behavior and, escape and attention were the most reported perceived functions of behavior. Challenging behavior is reported in DS by caregivers. Future research should be conducted to examine the prevalence and function of challenging behavior in DS to develop effective preventative approaches to challenging behavior while promoting skill acquisition.
唐氏综合症(DS)是一种由21号染色体三体引起的发育性残疾,与其他发育性残疾一样,唐氏综合症患者可能表现出具有挑战性的行为(例如,攻击、发脾气、自残行为;Feeley & Jones, 2006)。本研究的目的是通过Qualtrics对退行性痴呆患者的照顾者进行调查,以评估退行性痴呆患者是否存在挑战性行为。我们的调查链接已发送给支持DS人口的国家和地方组织,并要求传播该链接。由于回应有限,我们对调查进行了修改(缩短和重组),并将修改后的调查链接通过Facebook传播给关注DS的小组。虽然这两项调查得到的答复有限,但初步发现值得进一步探讨。攻击、不服从和发脾气行为是最常见的行为,逃避和注意力是最常见的行为感知功能。照顾者报告了退行性痴呆患者的挑战性行为。未来的研究应进一步研究挑战行为在退步儿童中的流行程度和作用,以制定有效的预防方法,同时促进技能习得。
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引用次数: 0
The Pathogenesis of Adrenoleukodystrophy 肾上腺脑白质营养不良的发病机制
IF 1.1 Q3 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2023-05-31 DOI: 10.47611/jsrhs.v12i2.4272
Kyle Wang, Sajeth Dinakaran
Adrenoleukodystrophy (ALD) is a rare, inherited disorder that affects the brain, spinal cord, and adrenal glands. It is caused by mutations in the ABCD1 gene, which provides instructions for making a protein called ABCD1, which is involved in the metabolism of very long-chain fatty acids (VLCFAs). In ALD, the body cannot properly break down and clear VLCFAs, which can lead to the accumulation of these fatty acids in the brain and other tissues. This accumulation can cause inflammation and damage to cells and tissues, leading to various symptoms.  Symptoms of ALD may vary depending on the type of ALD and the severity of the condition. Common symptoms include neurological problems, such as difficulty walking, speaking, behavioral changes, and problems with the adrenal gland, such as adrenal insufficiency which is a condition in which the adrenal glands do not produce enough hormones. ALD is a progressive disorder, meaning symptoms may worsen over time if left untreated. Treatment for ALD typically involves medications and supportive care to manage symptoms and prevent complications. Sometimes, a bone marrow transplant may be recommended to replace damaged cells and tissues. Genetic testing is available for ALD and can be used to diagnose the disorder and identify people at risk of developing it. Early diagnosis and treatment can help improve the chances of a full recovery and a good quality of life for people with ALD.
肾上腺脑白质营养不良(ALD)是一种罕见的遗传性疾病,影响大脑、脊髓和肾上腺。它是由ABCD1基因突变引起的,该基因为制造一种名为ABCD1的蛋白质提供指令,这种蛋白质参与了长链脂肪酸(VLCFAs)的代谢。在ALD中,身体不能适当地分解和清除VLCFAs,这可能导致这些脂肪酸在大脑和其他组织中积累。这种积累会引起炎症,损害细胞和组织,导致各种症状。ALD的症状可能根据ALD的类型和病情的严重程度而有所不同。常见的症状包括神经系统问题,如行走困难、说话困难、行为改变和肾上腺问题,如肾上腺功能不全,即肾上腺不能产生足够的激素。ALD是一种进行性疾病,如果不及时治疗,症状可能会随着时间的推移而恶化。ALD的治疗通常包括药物治疗和支持性护理,以控制症状和预防并发症。有时,可能会建议进行骨髓移植来替换受损的细胞和组织。ALD的基因检测是可用的,可以用来诊断这种疾病,并确定有患病风险的人。早期诊断和治疗可以帮助提高老年痴呆症患者完全康复的机会和良好的生活质量。
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引用次数: 0
Impact of Social/Traditional Media on Political Polarization 社会/传统媒体对政治两极分化的影响
IF 1.1 Q3 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2023-05-31 DOI: 10.47611/jsrhs.v12i2.4296
Shubhi Goyal, Mukul Goyal
There is a common perception that political polarization is increasing in American society and the blame is often assigned to highly partisan traditional media (e.g., TV news channels) and the emergence of social media echo chambers as the major influencers of political opinion. In this paper, we examine the impact of traditional and social media on political polarization in society via simulations. These simulations examine what happens when a population with normally distributed unipolar political views is exposed to social/traditional media espousing very different types of political views. Our simulations reveal that the political polarization in a population is deeply affected by the political views espoused in the media. If the media is primarily unipolar in terms of political views, the population ultimately become politically unipolar as well. On the other hand, if the media is politically bipolar, the population ultimately becomes politically bipolar. Interestingly, the simulations reveal that social media echo chambers can undo the polarizing impact of partisan traditional media if the echo chambers strictly show content matching the current political views of the users. However, if social media echo chambers expose the users to extreme political views, a population that is initially unipolar in political views will ultimately look like two different populations with very different political centers.
人们普遍认为,美国社会的政治两极分化正在加剧,这通常归咎于高度党派化的传统媒体(如电视新闻频道),以及作为政治观点主要影响因素的社交媒体回音室的出现。在本文中,我们通过模拟研究了传统媒体和社交媒体对社会政治极化的影响。这些模拟研究了当一个具有正态分布的单极政治观点的人群暴露在支持非常不同类型政治观点的社会/传统媒体中时会发生什么。我们的模拟表明,人口中的政治两极分化深受媒体所支持的政治观点的影响。如果媒体在政治观点上主要是单极的,那么民众在政治上最终也会成为单极的。另一方面,如果媒体在政治上两极分化,那么民众最终也会在政治上两极分化。有趣的是,模拟显示,如果回音室严格显示与用户当前政治观点相匹配的内容,社交媒体回音室可以消除党派传统媒体的两极分化影响。然而,如果社交媒体回音室让用户接触到极端的政治观点,那么最初政治观点单极的人群最终会看起来像两个拥有截然不同政治中心的不同人群。
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引用次数: 0
The Application of Artificial Intelligence and Machine Learning to Anesthesiology 人工智能和机器学习在麻醉学中的应用
IF 1.1 Q3 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2023-05-31 DOI: 10.47611/jsrhs.v12i2.4403
Srinithya Kothapalli, Rajagopal Appavu
This research paper explores the application of artificial intelligence (AI) and machine learning (ML) in anesthesiology. AI and ML have the potential to improve patient outcomes and enhance clinical decision-making by enabling anesthesiologists to monitor patient vital signs in real-time, predict the likelihood of complications, and optimize drug dosages to minimize side effects and enhance efficacy. The Hypotension Prediction Index algorithm is a compelling example of how AI and ML can be utilized to improve intraoperative patient care. However, there is a need for further research and validation to ensure the safety and efficacy of these technologies in clinical practice. Future advancements in AI and ML techniques are likely to result in more sophisticated and accurate predictive models, decision support tools, and monitoring systems that will ultimately benefit patients undergoing anesthesia. Overall, the application of AI and ML in anesthesiology presents a promising avenue for improving patient care and outcomes.
本文探讨了人工智能(AI)和机器学习(ML)在麻醉学中的应用。人工智能和机器学习有可能改善患者的治疗结果,增强临床决策,使麻醉师能够实时监测患者的生命体征,预测并发症的可能性,并优化药物剂量以减少副作用并提高疗效。低血压预测指数算法是人工智能和机器学习如何用于改善术中患者护理的一个引人注目的例子。然而,还需要进一步的研究和验证,以确保这些技术在临床实践中的安全性和有效性。人工智能和机器学习技术的未来发展可能会产生更复杂、更准确的预测模型、决策支持工具和监测系统,最终使麻醉患者受益。总的来说,人工智能和机器学习在麻醉学中的应用为改善患者护理和结果提供了一条有前途的途径。
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引用次数: 0
The Impact of Bilingualism on Cognitive Reserve as a Protectant Against Cognitive Decline 双语对认知储备的影响及其对认知衰退的保护作用
IF 1.1 Q3 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2023-05-31 DOI: 10.47611/jsrhs.v12i2.4229
Leila Zak, Arianna D Cascone
Cognitive decline exists on a spectrum, ranging from mild cognitive impairment to dementia. These two diagnoses encompass a group of symptoms rooted in the progressive decline of cognitive function, impairing aspects like memory, decision-making, language use, and locomotion. This review centers upon the premise of cognitive reserve, an intangible measure of the brain’s resilience and capacity to compensate for damage, and its relationship with the preservation of cognitive function later in life. Bilingualism constitutes one of many contributing factors to a higher cognitive reserve; however, this term fails to reflect the unique linguistic profile intrinsic to every individual—including whether a second language was acquired during childhood or later in life. Therefore, a distinction between “acquired” and “lifelong” bilingualism is made. Through the analysis of task-based and neuroimaging data, this review article elucidates the impact both forms of bilingualism have on cognitive reserve as a protectant against cognitive decline, revealing that resultant neuroprotective advantage is most salient when both languages are used regularly, in diverse environments, and in an active manner. These practices are observed in both acquired and lifelong bilinguals to varying degrees, which are contextualized and explored in detail within the review.
认知能力下降存在于一个范围内,从轻度认知障碍到痴呆。这两种诊断包含了一组植根于认知功能逐渐衰退的症状,损害了记忆、决策、语言使用和运动等方面。这篇综述的中心是认知储备的前提,认知储备是一种无形的衡量大脑的弹性和补偿损伤的能力,以及它与以后生活中认知功能的保存的关系。双语能力是提高认知储备的众多因素之一;然而,这一术语未能反映每个人固有的独特语言特征,包括第二语言是在童年时期还是在以后的生活中习得的。因此,“获得性”和“终身”双语的区别是明确的。通过对任务基础和神经影像学数据的分析,本文阐述了两种形式的双语对认知储备的影响,并揭示了当两种语言在不同的环境中以积极的方式经常使用时,所产生的神经保护优势最为突出。这些实践在习得性和终身双语者中都有不同程度的观察,本文将对其进行背景化和详细探讨。
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引用次数: 0
Impacts of seasonal variations of the Tropical Pacific ocean temperatures on upper ocean oxygen response 热带太平洋温度季节变化对上层海洋氧响应的影响
IF 1.1 Q3 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2023-05-31 DOI: 10.47611/jsrhs.v12i2.4397
Christina Kim
The El Niño–Southern Oscillation (ENSO) is the most dominant natural variability in the Earth system, which represents seasonal-to-interannual variations of the surface equatorial Pacific Ocean temperatures and subsurface ocean interior. Impacting the physical upper ocean characteristics, ENSO exerts significant influences on the marine ecosystem, such as oxygen and phytoplankton concentrations via strong quasiperiodic oscillation between El Niño (warm phase) and La Niña (cold phase) events. The present study uses observational reanalysis and satellite data to investigate seasonal variations of ENSO and their impacts on marine biogeochemical processes. The results show that the oxygen and chlorophyll anomalies in the upper ocean exhibit different seasonal responses to ENSO. While both the summer and winter season biological responses significantly lag ENSO, the concentration of oxygen and phytoplankton during summer (winter) has no (large) concurrent covariability with ENSO. Given a strong negative correlation between chlorophyll-based indices and El Niño events, increasing mean ocean temperatures and ocean extreme events may induce lower upper-ocean oxygen levels, leading to possible risks in the ecosystem over the tropical Pacific Ocean.
El Niño-Southern涛动(ENSO)是地球系统中最主要的自然变率,它代表了赤道太平洋表层和海底海洋内部温度的季节-年际变化。ENSO通过El Niño(暖相)和La Niña(冷相)之间强烈的准周期振荡,影响海洋上层物理特征,对海洋生态系统的氧和浮游植物浓度产生显著影响。本研究利用观测再分析和卫星资料研究ENSO的季节变化及其对海洋生物地球化学过程的影响。结果表明,上层海洋氧和叶绿素异常对ENSO有不同的季节响应。夏季和冬季的生物响应都明显滞后于ENSO,但夏季(冬季)的氧和浮游植物浓度与ENSO没有(大)的同步协变性。鉴于叶绿素指数与El Niño事件之间存在强烈的负相关关系,平均海洋温度升高和海洋极端事件可能导致海洋上层氧含量降低,从而可能导致热带太平洋生态系统的风险。
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引用次数: 0
The Potential of microalgae for cellulose degradation and utilization for biofuel application 微藻在纤维素降解和生物燃料利用方面的潜力
IF 1.1 Q3 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2023-05-31 DOI: 10.47611/jsrhs.v12i2.4430
Scott Shin, Juliana Caulkins, Leya Joykutty
As society is becoming more reliant on fuels, a more sustainable form of energy must be investigated. Another presiding issue is the output of cellulose left over from other plants that are used for biofuels, such as corn. However, the microalgae, Chlamydomonas Reinhardtii, a unicellular organism, is an ideal source of energy, as there is evidence that it contains the genes that are responsible for the encoding of Cellulases, which allow for the degradation of cellulose, such as endoglucanases. Chlamydomonas Reinhardtii typically lives in both soil and water environments, a photosynthetic organism that utilizes light as an energy source. The uncommon trait for microalgae to express cellulase allows for external sources of carbon to be utilized by the microorganism, which could affect the biological output of macromolecules common in biofuels such as lipids and carbohydrates. The study aims to compare not only the cellulase expression levels of Chlamydomonas Reinhardtii, but also see how the lipid output of the microalgae compares to other microorganisms used in the biofuel industry such as Chlorella Vulgaris, another phototrophic microalgae, which is used for direct fuel. Additionally, Trichoderma Reesei will also be compared, which is another microorganism that is used for biofuel production. However, the industry utilizes Trichoderma Reesei’s ability to produce cellulase, rather than just taking directly from the microorganism. The conclusions unfortunately did not show any cellulase expression, and biofuel output favored algae
随着社会越来越依赖燃料,必须研究一种更可持续的能源形式。另一个主要问题是用于生物燃料的其他植物(如玉米)剩余的纤维素的产量。然而,微藻,莱茵衣藻,一种单细胞生物,是一种理想的能量来源,因为有证据表明它含有负责纤维素酶编码的基因,纤维素酶允许纤维素降解,如内切葡聚糖酶。莱茵衣藻通常生活在土壤和水环境中,是一种利用光作为能量来源的光合生物。微藻表达纤维素酶的不寻常特性允许微生物利用外部碳源,这可能会影响生物燃料中常见的大分子(如脂质和碳水化合物)的生物输出。这项研究的目的不仅是比较莱茵衣藻的纤维素酶表达水平,而且还研究了微藻的脂质输出与生物燃料工业中使用的其他微生物(如另一种用于直接燃料的光养微藻小球藻)的比较。此外,还将比较里氏木霉,这是另一种用于生物燃料生产的微生物。然而,该行业利用里氏木霉生产纤维素酶的能力,而不是直接从微生物中提取。不幸的是,结论没有显示任何纤维素酶的表达,生物燃料的产出有利于藻类
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引用次数: 0
Using EEG Data to Detect Eye Movement 利用脑电图数据检测眼球运动
IF 1.1 Q3 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2023-05-31 DOI: 10.47611/jsrhs.v12i2.4231
Aishwaroopa Narayanan
In this paper, we show that it is possible to use EEG data to detect eye movement using machine learning. By recognizing eye movement through EEG results, our goal is to help individuals with disabilities better control object movement and perform daily activities independently. This is especially important as many disabled individuals rely on assistance from others for their daily needs, which can be burdensome for the person providing help. To achieve these objectives, we trained different machine learning models using a data set of eye-state classification from Kaggle. We analyzed the results to assess the accuracy of a KNN (K Nearest Neighbors) model. With the model achieved an accuracy of 95.23% in detecting eye movement in patients. These findings suggest that the model could be effectively utilized in the future, with further research to assist individuals with disabilities. Overall, our research suggests that it is possible to recognize eye movement through EEG results reliably. Further research in this area could lead to the development of more effective and personalized interventions for individuals with poor hand-eye coordination.
在本文中,我们证明了使用机器学习使用EEG数据来检测眼球运动是可能的。通过脑电图结果识别眼球运动,我们的目标是帮助残疾人更好地控制物体运动和独立进行日常活动。这一点尤其重要,因为许多残疾人依靠他人的帮助来满足他们的日常需求,这对提供帮助的人来说可能是负担。为了实现这些目标,我们使用来自Kaggle的眼状态分类数据集训练了不同的机器学习模型。我们对结果进行了分析,以评估KNN (K近邻)模型的准确性。该模型对患者眼球运动的检测准确率达到95.23%。这些发现表明,该模型可以在未来有效地利用,并进一步研究以帮助残疾人。总之,我们的研究表明,通过脑电图结果可靠地识别眼球运动是可能的。在这一领域的进一步研究可以为手眼协调能力差的人提供更有效和个性化的干预措施。
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引用次数: 0
Using Machine Learning to Forecast Progression from Cognitively Normal to Alzheimer's Disease 使用机器学习预测从认知正常到阿尔茨海默病的进展
IF 1.1 Q3 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2023-05-31 DOI: 10.47611/jsrhs.v12i2.4347
Ann Song
Alzheimer's Disease (AD) affects approximately 50 million individuals worldwide and is estimated to rise to 152 million by 2050. There is currently no treatment for AD that halts the progression from cognitively normal (CN) and/or mild cognitive impairment (MCI) to AD. The ability to predict disease progression will allow for early treatment. While Machine Learning (ML) has been successful in diagnosing the cognitive state, further improvement is necessary for predicting progression. In this study, Random Forest and Bagging Decision Tree Recursive Feature Elimination (RFE) was utilized to ascertain the cognitive state and forecast progression. Clinical diagnoses, demographics, and post-processed PET and MRI scans used in this study were obtained from the Open Access Series of Imaging Studies (OASIS). The findings suggest that aging and lower levels of education are associated with higher risk. The study found that ML using post-processed MRI and PET scans, particularly RFE ML, is effective in diagnosing cognitive states with 90% accuracy. It can predict progression from CN to MCI or AD with 85% accuracy, which is significantly higher than the average reported in literature. Patients with progression from CN to AD were distinguished by elevated amyloid deposition, hippocampus and amygdala atrophy, left accumbens atrophy, thinning of the left hemisphere temporal, and enlarged inferior lateral ventricles. The study demonstrated that RFE ML is effective in diagnosing and predicting the progression of AD. Future studies will concentrate on identifying the specific regions of amyloid plaque that have the most significant impact on cognitive state and progression.  
阿尔茨海默病(AD)影响全球约5000万人,预计到2050年将增加到1.52亿人。目前还没有治疗阿尔茨海默病的方法可以阻止从认知正常(CN)和/或轻度认知障碍(MCI)向阿尔茨海默病的进展。预测疾病进展的能力将允许早期治疗。虽然机器学习(ML)在诊断认知状态方面已经取得了成功,但在预测进展方面还需要进一步的改进。在本研究中,随机森林和Bagging决策树递归特征消除(RFE)被用于确定认知状态和预测进程。本研究中使用的临床诊断、人口统计、后处理PET和MRI扫描数据均来自影像研究开放获取系列(OASIS)。研究结果表明,年龄和低教育水平与更高的风险有关。研究发现,使用后处理MRI和PET扫描的ML,特别是RFE ML,在诊断认知状态方面具有90%的准确率。该方法预测CN向MCI或AD进展的准确率为85%,显著高于文献报道的平均水平。从CN进展到AD的患者表现为淀粉样蛋白沉积升高、海马和杏仁核萎缩、左伏隔脑萎缩、左半球颞叶变薄、下侧脑室增大。研究表明,RFE ML在诊断和预测AD进展方面是有效的。未来的研究将集中在确定淀粉样斑块的特定区域,对认知状态和进展有最重要的影响。
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引用次数: 0
Non-Athlete High School Students' Music Usage During Exercise 非运动员高中生在运动中的音乐使用
IF 1.1 Q3 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2023-05-31 DOI: 10.47611/jsrhs.v12i2.4380
Wudi Ding, Roger Worthington, Bridget Hamill
With the invention of technology devices such as wireless headphones and portable Bluetooth speakers, teenagers have gradually become heavily reliant on music during exercising/practicing. To find the underlying reason for this habit, an anonymous survey was sent out to 50 high school boarding students in America on 9th December 2022 regarding the purpose of listening to music during exercising/practicing, and their music preferences. Music supports both mental and physical aspects during athletic training. A slight correlation was found between music preferences specifically for the purpose of athletic training, and a slight correlation was found between preferences for genres of music and preference for each aspect of music. 
随着无线耳机和便携式蓝牙扬声器等科技设备的发明,青少年在锻炼/练习时逐渐变得非常依赖音乐。为了找出这种习惯的潜在原因,我们于2022年12月9日对美国50名高中寄宿学生进行了一项匿名调查,调查内容是在锻炼/练习时听音乐的目的以及他们的音乐偏好。在运动训练中,音乐对精神和身体都有帮助。研究发现,以运动训练为目的的音乐偏好之间存在轻微的相关性,对音乐类型的偏好与对音乐各个方面的偏好之间也存在轻微的相关性。
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引用次数: 0
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Journal of Student Affairs Research and Practice
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