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Functional Capacity and Quality of Life in Elderly Patients With Knee Osteoarthritis. 老年膝骨关节炎患者的功能能力和生活质量。
IF 1.5 Q3 RHEUMATOLOGY Pub Date : 2024-12-01 DOI: 10.1002/msc.70027
Alia Fazaa, Mariem Rachdi, Leila Ben Salem, Meriam El Ghardallou, Saoussen Miladi, Hiba Boussaa, Yasmine Makhlouf, Kaouther Ben Abdelghani, Ahmed Laatar

Background: Knee Osteoarthritis (KOA) can cause considerable impairment of functional capacity and quality of life (QoL), especially in elderly individuals.

Objectives: To evaluate the impact of KOA on the functional capacity and QoL of elderly patients and to identify the factors associated with their impairment.

Methods: This was a cross-sectional study including patients aged 65 years or more with primary KOA. Functional capacity was assessed using the WOMAC index and QoL using the WHOQOL-OLD instrument. The p significance level was set at 0.05.

Results: Fifty patients were included, 3 men and 47 women, with a mean age of 71.9 ± 6.3 years. The mean WOMAC total score was 49.2 ± 21.7, WOMAC pain 12 ± 5.2, WOMAC function 33.4 ± 15.2 and WOMAC stiffness 4 ± 2.6. Factors associated with better functional capacity were the use of analgesics, functional rehabilitation and physical activity. The mean WOQOL-OLD total score was 84.2 ± 13.4. The autonomy and intimacy dimensions had the highest scores (92.1 ± 13.8 and 91.3 ± 16.5 respectively). The death and dying dimension had the lowest score (69.9 ± 37.1). Factors associated with a poor QoL were diabetes, unilateral involvement, duration of KOA, absence of analgesic treatment and the absence of physical activity. Functional limitation was significantly associated with poorer QoL.

Conclusion: In our study, KOA was found to be associated with impaired functional capacity and QoL among elderly patients. Comorbidities, inadequate use of analgesics and lack of physical activity seem to be determining factors contributing to this impairment.

背景:膝骨关节炎(KOA)可引起相当大的功能能力和生活质量(QoL)的损害,特别是在老年人中。目的:评价KOA对老年患者功能能力和生活质量的影响,探讨老年患者功能障碍的相关因素。方法:这是一项横断面研究,包括65岁或以上的原发性KOA患者。使用WOMAC指数评估功能能力,使用WHOQOL-OLD仪器评估生活质量。p显著性水平设为0.05。结果:纳入患者50例,男3例,女47例,平均年龄71.9±6.3岁。平均WOMAC总分49.2±21.7分,WOMAC疼痛12±5.2分,WOMAC功能33.4±15.2分,WOMAC僵硬度4±2.6分。与更好的功能能力相关的因素是镇痛药的使用、功能康复和身体活动。平均WOQOL-OLD总分为84.2±13.4分。自主性和亲密性维度得分最高,分别为92.1±13.8分和91.3±16.5分。死亡和临终维度得分最低(69.9±37.1)。与不良生活质量相关的因素有糖尿病、单侧受累、KOA持续时间、缺乏镇痛治疗和缺乏体育活动。功能限制与较差的生活质量显著相关。结论:在我们的研究中,发现KOA与老年患者的功能能力和生活质量受损有关。合并症、镇痛药使用不足和缺乏身体活动似乎是导致这种损害的决定性因素。
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引用次数: 0
Associations Between Patient-Reported Sleep Disturbance, Joint-Specific Health, and Global Health Before and After Total Hip or Knee Arthroplasty. 全髋关节或膝关节置换术前后患者报告的睡眠障碍、关节特异性健康和整体健康之间的关系
IF 1.5 Q3 RHEUMATOLOGY Pub Date : 2024-12-01 DOI: 10.1002/msc.70029
Uma Balachandran, Hayley E Raymond, Nicholas L Pitaro, Michael M Herrera, Brocha Z Stern, Darwin D Chen, Brett L Hayden, Jashvant Poeran, Calin S Moucha
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引用次数: 0
Predictive Factors of Short Inpatient Stay Following Total Knee Replacement. 全膝关节置换术后短期住院的预测因素。
IF 1.5 Q3 RHEUMATOLOGY Pub Date : 2024-12-01 DOI: 10.1002/msc.70022
Zi Qiang Glen Liau, Jonathan Zhi Kai Toh, Lakshmanan Sathappan, Yau Hong Ng

Introduction: Enhanced Recovery after Surgery (ERAS) protocols adopt a multidisciplinary approach in perioperative care to reduce Length of Stay (LOS). This study aims to identify predictive factors resulting in short-stay following TKR with an ERAS programme.

Methods: Retrospective analysis was performed on a consecutive series of patients who underwent unilateral TKR by a single surgeon in a tertiary institution between August 2019 and December 2021. Patient demographics, comorbidities and length of stay were collected using Electronic Medical Records. Short-stay was defined as LOS within 1 day or less, while standard-stay was defined as LOS exceeding 2 days or more. Statistical analysis was performed using R version 4.3.1. Logistic regression was performed for multivariate analysis.

Results: Ninety-nine patients were included in the study, comprising 45 short-stay patients and 54 standard-stay patients. Short-stay patients were significantly younger (mean 66.1, 95% CI [64.5, 67.7], p = 0.0212) than standard-stay patients (mean 69.2, 95% CI [67.1, 71.2]). There was a significantly lower mean BMI among short-stay patients (26.98, 95% CI [25.52, 28.45], p = 0.021) than among standard-stay patients (29.31, 95% CI [27.96, 30.66]). A significantly higher proportion of short-stay patients (84.4%, 95% CI [73.4, 95.5], p = 0.00132) were premorbid community ambulant without aids than standard-stay patients (51.9%, 95% CI [38.1, 65.6]). There was no significant difference in sex, race, smoking, American Society of Anaesthesiologists score and Charlson Comorbidity Index (p > 0.05). Multivariate logistic regression revealed the following significant factors: Age < 75 (p = 0.0293), BMI < 25 (p = 0.00688), and premorbid community ambulant without aids (p = 0.0402).

Conclusions: In conclusion, predictive factors for short-stay after TKR include age < 75, BMI < 25 and being premorbid community ambulant without aids.

简介:增强术后恢复(ERAS)协议在围手术期护理中采用多学科方法来减少住院时间(LOS)。本研究旨在通过ERAS计划确定导致TKR后短期住院的预测因素。方法:回顾性分析2019年8月至2021年12月在某高等教育机构由一名外科医生连续行单侧TKR的患者。使用电子病历收集患者人口统计资料、合并症和住院时间。短期停留定义为1天以内的停留时间,标准停留定义为2天以上的停留时间。采用R 4.3.1版本进行统计分析。采用Logistic回归进行多因素分析。结果:99例患者纳入研究,其中短期住院患者45例,标准住院患者54例。短期住院患者明显比标准住院患者年轻(平均66.1,95% CI [64.5, 67.7], p = 0.0212)(平均69.2,95% CI[67.1, 71.2])。短期住院患者的平均BMI (26.98, 95% CI [25.52, 28.45], p = 0.021)明显低于标准住院患者(29.31,95% CI[27.96, 30.66])。短住院患者(84.4%,95% CI [73.4, 95.5], p = 0.00132)发病前无辅助的社区门诊患者比例明显高于标准住院患者(51.9%,95% CI[38.1, 65.6])。性别、种族、吸烟、美国麻醉医师学会评分、Charlson合病指数差异无统计学意义(p < 0.05)。结论:TKR术后短期住院的预测因素包括年龄
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引用次数: 0
Rehabilitation Interventions for Adults With Complex Regional Pain Syndrome: A Scoping Review Protocol. 成人复杂性区域疼痛综合征患者的康复干预:范围审查协议》。
IF 1.5 Q3 RHEUMATOLOGY Pub Date : 2024-12-01 DOI: 10.1002/msc.1956
Marc A Pique Batalla, Ann Van de Winckel, Nicola E Walsh, Jennifer S Lewis

Objectives: This scoping review will explore the literature related to rehabilitation interventions for the treatment of adults living with complex regional pain syndrome (CRPS), describe the domains and outcome measures used to assess their effectiveness, and examine the neurophysiological bases of these interventions.

Introduction: The unremitting symptoms of CRPS, a chronic pain condition, are associated with long-term disability, poor psychological health, decreased emotional and social well-being, and reduced quality of life. Effective treatment for persistent symptoms is notoriously difficult. Therapeutic approaches such as graded motor imagery or pain exposure therapy are recommended for CRPS but show mixed results, insufficient effectiveness, variability in outcome measures, and unclear neurophysiological bases.

Inclusion criteria: This review will consider studies that include any form of non-invasive rehabilitation intervention delivered by a healthcare professional in any setting for adults with a CRPS diagnosis. Quantitative, qualitative and observational studies, text and opinion papers will be considered.

Methods: The Joanna Briggs Institute (JBI) methodology will be used to conduct this scoping review. MEDLINE, Embase, Scopus, APA PsycINFO, CINAHL, Cochrane, OpenGrey Google and ProQuest Dissertations and Theses Global (ProQuest) will be searched for studies in English published between 2007 and 2024. Two independent reviewers will screen the titles, abstracts, and full texts of the selected studies. Data collection will be performed using a tool developed by the researchers based on the standardised JBI tool. Data will be presented in a comprehensive narrative summary.

Trail registration: https://doi.org/10.17605/OSF.IO/P967T.

研究目的:本范围综述将探讨与治疗成人复杂性区域疼痛综合症(CRPS)的康复干预措施相关的文献,描述用于评估其有效性的领域和结果测量,并研究这些干预措施的神经生理学基础:导言:CRPS 是一种慢性疼痛疾病,其持续症状与长期残疾、心理健康状况不佳、情绪和社交能力下降以及生活质量降低有关。众所周知,有效治疗顽固性症状非常困难。建议采用分级运动想象或疼痛暴露疗法等治疗方法来治疗 CRPS,但这些方法的效果参差不齐、有效性不足、结果测量多变且神经生理学基础不明确:本综述将考虑包括由医护人员在任何环境下为确诊为 CRPS 的成人提供的任何形式的非侵入性康复干预的研究。研究方法:乔安娜-布里格斯研究所(Joanna Briggs Institute)将对所有研究进行筛选:将采用乔安娜-布里格斯研究所(JBI)的方法来进行此次范围界定综述。将在 MEDLINE、Embase、Scopus、APA PsycINFO、CINAHL、Cochrane、OpenGrey Google 和 ProQuest Dissertations and Theses Global (ProQuest) 中检索 2007 年至 2024 年间发表的英文研究。两名独立审稿人将对所选研究的标题、摘要和全文进行筛选。数据收集将使用研究人员根据标准化的 JBI 工具开发的工具进行。数据将以综合叙述性摘要的形式呈现。路径注册:https://doi.org/10.17605/OSF.IO/P967T。
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引用次数: 0
Classification of Physical Activity Programs Based on the Kellgren & Lawrence Scale for Knee Osteoarthritis: A Systematic Review. 根据 Kellgren 和 Lawrence 量表对膝关节骨性关节炎的体育锻炼计划进行分类:系统回顾
IF 1.5 Q3 RHEUMATOLOGY Pub Date : 2024-12-01 DOI: 10.1002/msc.70019
Alberto Canzone, Federico Roggio, Antonino Patti, Valerio Giustino, Carmen Mannucci, Debora Di Mauro, Giuseppe Musumeci, Antonino Bianco, Fabio Trimarchi

Introduction: Knee osteoarthritis is a common orthopaedic disease, is the leading cause of disability in the elderly, and can lead to pain, loss of function, and reduced quality of life. This research aims to determine how PA programs can be effectively classified and customised to align with the stages of knee OA according to the KL classification.

Objective: The research aims to fill the gap in understanding the relationship between the type and intensity of PA and the stages of OA as defined by the KL classification.

Materials and methods: A systematic search was performed using PubMed, Web of Science, and Scopus databases. This review included different types of studies published after January 1, 2013.

Results: Two thousand one hundred and thirty-six were picked up and only nine articles met the inclusion criteria. The beneficial effects of exercise were found in the function of the joints, pain, and quality of life. Aerobic, isometric, and resistance training showed positive effects and presented improvements in physical function, quality of life, and pain.

Conclusion: The exercise programs appear to be both safe and effective in subjects with knee osteoarthritis with regard to quality of life, pain, and knee function.

Trial registration: PROSPERO registration number: CRD42024550463.

导言:膝关节骨关节炎是一种常见的骨科疾病,也是老年人致残的主要原因,可导致疼痛、功能丧失和生活质量下降。本研究旨在确定如何根据 KL 分类法对 PA 程序进行有效分类,并根据膝关节 OA 的不同阶段进行定制:本研究旨在填补在了解 PA 的类型和强度与 KL 分类所定义的 OA 阶段之间的关系方面存在的空白:使用 PubMed、Web of Science 和 Scopus 数据库进行了系统检索。该综述包括 2013 年 1 月 1 日之后发表的不同类型的研究:结果:共检索到 236 篇文章,只有 9 篇符合纳入标准。研究发现,运动对关节功能、疼痛和生活质量都有益处。有氧、等长和阻力训练均显示出积极的效果,并在身体功能、生活质量和疼痛方面有所改善:结论:在生活质量、疼痛和膝关节功能方面,锻炼计划似乎对膝关节骨性关节炎患者既安全又有效:试验注册:PROSPERO 注册号试验注册:PROSPERO 注册号:CRD42024550463。
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引用次数: 0
Healthcare Utilisation in Danish Primary Care Among Patients With Low Back or Neck/Thoracic Spine Pain Before and After Assessment in Secondary Care. 丹麦初级保健中腰背或颈/胸椎疼痛患者在二级保健评估前后的医疗保健利用
IF 1.5 Q3 RHEUMATOLOGY Pub Date : 2024-12-01 DOI: 10.1002/msc.70017
Stine Clausen, Jan Hartvigsen, Melker S Johansson, Lise Grethe Kjønø, Søren Grøn, Christian V Skovsgaard, Kjersti Storheim, Karin Magnusson, Margreth Grotle, Casper Nim

Objectives: To describe characteristics and primary healthcare utilisation in Danish patients with low back pain (LBP) or neck/thoracic spine pain (NTP) 8 years before and 2 years after assessment in secondary care.

Methods: In this cohort study, we included patients aged ≥ 18 who were assessed at an outpatient spine clinic from 2013 to 2021 and linked self-reported information with national registry data. We calculated the prevalence of all-cause healthcare utilisation in primary care. Then, we determined changes in the number of consultations from before to after assessment in secondary care using generalised estimating equations.

Results: We included 56,949 LBP patients and 18,926 NTP patients. The baseline characteristics were similar overall. For both LBP and NTP, all-cause healthcare utilisation increased slightly over time, with a substantial increase in the quarter before the secondary care assessment and a decrease after. Before the assessment, almost all patients consulted general practitioners (95%), while some consulted physiotherapists or chiropractors (60%). Overall, consultations decreased by 19% and 17% for patients with LBP and NTP from 12 to 1 month before to 1-12 months after the assessment. In contrast, 13-24 months after assessment, we found a slight increase in consultations in both groups compared to the same period before.

Conclusions: Patients with LBP and NTP were similar and used similar primary healthcare, which slightly increased over the 10 years. As physiotherapists and chiropractors are first-line providers of guideline-recommended spine pain treatment, the finding that 40% did not consult these professions the year before the secondary care assessment indicates that not all patients receive recommended care before referral.

目的:描述丹麦腰痛(LBP)或颈/胸椎痛(NTP)患者在二级护理评估前8年和评估后2年的特征和初级保健利用情况。方法:在这项队列研究中,我们纳入了年龄≥18岁的患者,他们于2013年至2021年在一家脊柱门诊诊所接受评估,并将自我报告信息与国家登记数据联系起来。我们计算了初级保健中全因医疗保健利用的流行率。然后,我们使用广义估计方程确定二级护理评估前后咨询人数的变化。结果:我们纳入了56,949例LBP患者和18,926例NTP患者。基线特征总体上是相似的。对于LBP和NTP,全因医疗保健利用率随着时间的推移略有增加,在二级护理评估前的季度大幅增加,在二级护理评估后下降。在评估前,几乎所有患者(95%)都咨询全科医生,而部分患者(60%)咨询物理治疗师或脊医。总体而言,从评估前12至1个月到评估后1至12个月,LBP和NTP患者的咨询分别减少了19%和17%。相比之下,评估后13-24个月,我们发现两组的咨询与同期相比略有增加。结论:LBP和NTP患者相似,使用相似的初级保健,10年内略有增加。由于物理治疗师和脊椎按摩师是指南推荐的脊柱疼痛治疗的一线提供者,发现40%的患者在二级护理评估前一年没有咨询这些专业人员,这表明并非所有患者在转诊前都接受了推荐的治疗。
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引用次数: 0
Orthosis Management in Knee Osteoarthritis: Evaluating Existing Recommendations and Achieving Consensus on Implementation Through the Delphi Method. 膝关节骨性关节炎的矫形器管理:评估现有建议并通过德尔菲法达成共识。
IF 1.5 Q3 RHEUMATOLOGY Pub Date : 2024-12-01 DOI: 10.1002/msc.70018
Zilan Bazancir-Apaydin

Objective: The available evidence on orthosis management in the knee osteoarthritis (KOA) remains questionable. This study aims to evaluate existing recommendations and achieve consensus on their implementation through the modified Delphi method.

Methods: Experienced experts in orthosis management for KOA patients participated in three Delphi rounds. Each round involved addressing various questions related to recommended orthosis type such as insole, knee brace, footwear, indications and contraindications, dosage of orthosis usage, follow-up period, long-term side effects, fitting, and weaning procedure. Consensus was defined as  ≥ 70% agreement with a question.

Results: Consensus was achieved for all questions. Experts frequently recommended custom-made insoles, neoprene knee braces, and appropriate footwear. The recommended duration of insole and knee brace usage averaged 3-6 months. Insole usage was advised during all weight-bearing activities, while knee braces were suggested for 4-6 h per day. Experts recommended orthosis follow-up for an average of 4-6 months. Reduced compliance with orthoses was highlighted by experts as the most significant long-term side effect. The fitting of orthoses is typically evaluated through gait analyses, assessment of symptoms and comfort, and observation of the corrective effects on impaired biomechanics in the clinical setting. Besides, experts commonly recommend a gradual weaning process from orthoses.

Conclusions: This study addresses the existing lack of consensus on orthosis management in KOA and provides essential clinical practice recommendations from multidisciplinary experts.

目的:目前关于膝关节骨性关节炎(KOA)矫形器治疗的证据尚存疑问。本研究旨在评估现有的建议,并通过改进的德尔菲法对其实施达成共识。方法:对KOA患者的矫形器管理经验丰富的专家进行三次德尔菲调查。每一轮都涉及到与推荐的矫形器类型相关的各种问题,如鞋垫、膝托、鞋类、适应症和禁忌症、矫形器使用剂量、随访期、长期副作用、矫形器和脱机程序。共识定义为与问题的一致度≥70%。结果:所有问题均获得一致回答。专家经常建议定制鞋垫、氯丁橡胶护膝和合适的鞋子。鞋垫和护膝的推荐使用时间平均为3-6个月。建议在所有负重活动中使用鞋垫,而膝盖支架建议每天使用4-6小时。专家建议矫形器随访时间平均为4-6个月。专家强调,降低对矫形器的依从性是最显著的长期副作用。矫形器的装配通常通过步态分析、症状和舒适度评估以及观察临床环境中对受损生物力学的矫正效果来评估。此外,专家们通常建议逐渐脱离矫形器。结论:本研究解决了目前对KOA矫形器管理缺乏共识的问题,并提供了多学科专家的重要临床实践建议。
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引用次数: 0
Hand Performance Assessed by Functional Dexterity Test Correlates With Clinical Disease Activity but Remains Altered in Rheumatoid Arthritis Patients Achieving Treatment Goals: A Cross-Sectional Cohort Study. 通过功能灵巧测试评估的手的表现与临床疾病活动相关,但在实现治疗目标的类风湿关节炎患者中仍有改变:一项横断面队列研究
IF 1.5 Q3 RHEUMATOLOGY Pub Date : 2024-12-01 DOI: 10.1002/msc.70023
Aniela Shouval, Amihai Levkoviz, Shiri Keret, Itzhak Rosner, Irina Rokhyan, Boris Tchalabian, Esther Hof, Gleb Slobodin

Objectives: Direct hand function is not commonly evaluated in patients with rheumatoid arthritis (RA). The Functional Dexterity Test (FDT) assesses a patient's ability to use the hand for daily tasks and is an accepted quantitative assessment tool in occupational medicine. This pilot study aimed to examine the correlations of FDT-measured hand performance with disease activity status in a cohort of RA patients.

Methods: Forty-eight patients with established RA performed the FDT during their regular follow-up visits. The dominant and non-dominant hands were assessed separately. FDT results were compared among patients with active RA and Clinical Disease Activity Index (CDAI) > 10, RA patients achieving controlled disease activity state (CDAI ≤ 10), and 20 volunteers with no rheumatic disease.

Results: Mean FDT for the dominant hand was 43 s in active RA, 35 s in controlled RA, and 25 s in persons without arthritis. Corresponding FDT results for the non-dominant hand were 50, 38, and 29 s, respectively. FDT significantly correlated with CDAI in the entire cohort of RA patients and the subgroup with CDAI > 10. Patients with controlled disease, CDAI ≤ 10, still demonstrated significantly reduced hand performance compared with non-rheumatic controls.

Conclusions: FDT is a sensitive tool for assessing rheumatoid hand function. Reduced hand performance by FDT in many RA patients who have already achieved existing treatment goals speaks to the question of the suitability of direct hand performance assessment as an RA outcome measure.

目的:类风湿性关节炎(RA)患者通常不评估直接手功能。功能灵巧测试(FDT)评估患者使用手进行日常任务的能力,是职业医学中公认的定量评估工具。本初步研究旨在检查fdt测量的手部功能与RA患者疾病活动状态的相关性。方法:48例已确诊的RA患者在定期随访期间进行FDT。优势手和非优势手分别进行评估。比较活动期RA患者的FDT结果与临床疾病活动指数(CDAI) bbb10、达到疾病活动状态控制(CDAI≤10)的RA患者和20名无风湿病的志愿者。结果:活动性RA的优势手平均FDT为43 s,控制性RA为35 s,无关节炎者为25 s。非优势手对应的FDT结果分别为50,38和29s。在整个RA患者队列和CDAI亚组中,FDT与CDAI显著相关[10]。与非风湿病对照组相比,CDAI≤10的疾病控制患者仍表现出明显的手部功能下降。结论:FDT是评估类风湿手功能的灵敏工具。FDT降低了许多已经达到现有治疗目标的RA患者的手部功能,这说明了直接手部功能评估作为RA结果测量的适用性问题。
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引用次数: 0
Exploring Congruence Between Patient and Clinician Expectations of Benefit in the Non-Surgical Management of Common Musculoskeletal Conditions in Tertiary Care. 探讨三级护理中常见肌肉骨骼疾病非手术治疗中患者和临床医生期望获益的一致性。
IF 1.5 Q3 RHEUMATOLOGY Pub Date : 2024-12-01 DOI: 10.1002/msc.70036
Darryn Marks, Peter Window, Maree Raymer, Patrick Swete Kelly, Alison Smith, Graham MacGregor, Helen O'Gorman, Ellen Jang, Steve Erceg, Daniel Wickins, Grahame Milne, Helen Cooper, Ian Seels, Brendan Diplock, Nikhil Taneja, Ian McLoughlin, Steven M McPhail, Shaun O'Leary

Background: Patient and clinician expectations of benefit from recommended management approaches may potentially impact the success of managing musculoskeletal conditions.

Methods: This was a multisite study in an advanced practice musculoskeletal service across Queensland, Australia. Relationships between patient and clinician (advanced physiotherapy practitioner) expectations of benefit, patient characteristics, and clinical outcome recorded 6 months later were explored with regression analysis in 619 patients undergoing non-surgical multidisciplinary care for either knee osteoarthritis (n = 286), low back pain (n = 249) or shoulder impingement syndrome (n = 84).

Results: Patient and clinician expectation ratings had a weak positive association (standardized coefficient (β) 0.28, adjusted R2 0.09). Higher patient expectation ratings were associated with higher readiness for change scores (β 0.31, model adjusted R2 = 0.18), while higher clinician expectation ratings were associated with the condition managed, higher patient education level, lower potential presence of neuropathic pain or yellow flags, and more favourable radiological findings (model adjusted R2 0.4). Patient expectations and self-reported engagement with care were poorly correlated. Higher patient (β 0.33, adjusted R2 0.12) and clinician (β 0.32, adjusted R2 0.14) expectations were associated with better clinical outcomes. This positive association was stronger when patient and clinician expectation ratings were congruent.

Conclusions: Findings suggest that expected benefits from recommended care may impact outcomes and should be considered in the initial phases of management. In particular, congruence between patient and clinician expectations appears to have relevance to outcomes.

背景:患者和临床医生对推荐的管理方法获益的期望可能会潜在地影响管理肌肉骨骼疾病的成功。方法:这是一项在澳大利亚昆士兰州的高级实践肌肉骨骼服务的多地点研究。对619例因膝骨关节炎(n = 286)、腰痛(n = 249)或肩撞击综合征(n = 84)而接受非手术多学科治疗的患者进行回归分析,探讨患者和临床医生(高级物理治疗从业者)对获益的期望、患者特征和6个月后记录的临床结果之间的关系。结果:患者期望评分与临床医生期望评分呈弱正相关(标准化系数(β) 0.28,校正R2 0.09)。较高的患者期望评分与较高的改变准备评分相关(β 0.31,模型调整R2 = 0.18),而较高的临床医生期望评分与病情管理、较高的患者教育水平、较低的神经性疼痛或黄旗潜在存在以及更有利的放射学结果相关(模型调整R2 0.4)。患者期望与自我报告的护理参与度相关性很差。较高的患者(β 0.33,调整R2 0.12)和临床医生(β 0.32,调整R2 0.14)期望与较好的临床结果相关。当患者和临床医生的期望评分一致时,这种正相关更强。结论:研究结果表明,推荐治疗的预期益处可能会影响结果,应在治疗的初始阶段予以考虑。特别是,患者和临床医生期望之间的一致性似乎与结果相关。
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引用次数: 0
Canadian Patients With Axial Spondyloarthritis Require Almost a Decade To Be Diagnosed Leading to Severe Functional Limitation. Results From the International Map of Axial Spondyloarthritis (IMAS). 加拿大的中轴性脊柱炎患者需要近十年的时间才能确诊,导致严重的功能限制。结果来自国际轴性脊椎关节炎地图(IMAS)。
IF 1.5 Q3 RHEUMATOLOGY Pub Date : 2024-12-01 DOI: 10.1002/msc.70010
Proton Rahman, Marco Garrido-Cumbrera, Sherry Rohekar, Michael G Mallinson, Elie Karam, Algis V Jovaisas, Nigil Haroon, Jeff Beach, Artur J de Brum-Fernandes, Martin Cohen, Jonathan Chan, Jose Correa-Fernández, Patrick Leclerc, Robert D Inman

Objective: To evaluate the sociodemographic characteristics and disease-related factors associated with diagnostic delay in Canadian patients with axial spondyloarthritis (axSpA).

Methods: Data from 542 Canadian patients who participated in the International Map of Axial Spondyloarthritis online survey were analysed. Diagnostic delay was calculated as the difference between age at diagnosis and age at onset of the first symptoms reported by participants. Univariate and multivariate analyses were used to evaluate possible factors associated with diagnostic delay.

Results: The mean age (± SD) of the surveyed participants was 44.3 ± 13.9 years and 63.1% were female. The average diagnostic delay was 9.0 ± 10.5 years (median, 5.0 years; interquartile range, 1.0-13.8). In the multivariate regression analysis, the three variables most strongly associated with longer diagnostic delay were use of nonsteroidal anti-inflammatory drugs (NSAIDs) (B = 2.991; 95% CI = 1.075-4.909), medium or high functional limitation (B = 1.541; 95%CI = 0.186-2.896), and number of HCPs seen before diagnosis (B = 1.524, 95%CI = 1.072-1.977).

Conclusion: Diagnostic delay continues to be a barrier to optimal care for Canadian axSpA patients. Significant diagnostic delay, associated with a high number of HCP visits prior to diagnosis, high use of NSAIDs, and marked functional limitation in daily life, illustrate the convoluted axSpA patient journey.

目的:评估加拿大轴性脊柱炎(axSpA)患者诊断延迟的社会人口学特征和疾病相关因素。方法:对542名参加国际轴性脊柱炎地图在线调查的加拿大患者的数据进行分析。诊断延迟计算为诊断年龄与参与者报告的首次症状发病年龄之间的差异。单因素和多因素分析用于评估与诊断延迟相关的可能因素。结果:调查对象的平均年龄(±SD)为44.3±13.9岁,女性占63.1%。平均诊断延迟为9.0±10.5年(中位数为5.0年;四分位数范围1.0-13.8)。在多因素回归分析中,与较长诊断延迟最相关的三个变量是使用非甾体抗炎药(NSAIDs) (B = 2.991;95% CI = 1.075-4.909),中高功能限制(B = 1.541;95%CI = 0.186 ~ 2.896),诊断前HCPs数(B = 1.524, 95%CI = 1.072 ~ 1.977)。结论:诊断延迟仍然是加拿大axSpA患者获得最佳护理的障碍。显著的诊断延迟,与诊断前HCP的大量就诊,非甾体抗炎药的大量使用以及日常生活中明显的功能限制有关,说明了axSpA患者的曲折历程。
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Musculoskeletal Care
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