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Correction: Applied humanities as the antidote for the malaise of bioethics. 更正:应用人文学科是治疗生命伦理问题的解药。
IF 2.3 2区 哲学 Q1 ETHICS Pub Date : 2025-01-10 DOI: 10.1007/s11019-025-10249-8
Monica Consolandi, Renzo Pegoraro
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引用次数: 0
Borderline personality disorder and moral responsibility. 边缘型人格障碍与道德责任
IF 2.3 2区 哲学 Q1 ETHICS Pub Date : 2025-01-04 DOI: 10.1007/s11019-024-10243-6
Agnès Baehni

This paper seeks to determine the extent to which individuals with borderline personality disorders can be held morally responsible for a particular subset of their actions: disproportionate anger, aggressions and displays of temper. The rationale for focusing on these aspects lies in their widespread acknowledgment in the literature and their plausible primary association with blame directed at BPD patients. BPD individuals are indeed typically perceived as "difficult patients" (Sulzer 2015:82; Bodner et al. 2011), significantly more so than schizophrenic or depressive patients (Markam 2003). The "responsibility question" for patients with BPD has already been raised (Martin 2010; Zachar and Potter 2009; Bray 2003), but this paper tackles it from a novel perspective. First, I narrow down the category of things for which the responsibility question is specific to individual with BPD. After that, I argue that some of the diagnosis criteria of BPD such as emotional instability or impulsivity might serve as excusing factors targeting the "control condition" on moral responsibility. Second, this paper also considers another widely accepted condition on moral responsibility: the epistemic condition. The view defended in the paper is that the answer to the responsibility question for individuals with BPD, concerning both the control condition and the epistemic condition, hinges on an understanding of their epistemic profile.

这篇论文试图确定边缘型人格障碍患者在多大程度上可以对他们的特定行为承担道德责任:过度的愤怒、攻击和发脾气。关注这些方面的基本原理在于它们在文献中得到了广泛的认可,并且它们似乎与针对BPD患者的指责有关。BPD患者通常被认为是“难相处的患者”(Sulzer 2015:82;Bodner et al. 2011),明显高于精神分裂症或抑郁症患者(Markam 2003)。BPD患者的“责任问题”已经被提出(Martin 2010;Zachar and Potter 2009;Bray 2003),但本文从一个新颖的角度来解决这个问题。首先,我缩小了责任问题特定于BPD患者的事情的范围。在此之后,我认为BPD的一些诊断标准,如情绪不稳定或冲动,可能成为针对道德责任的“控制条件”的借口因素。其次,本文还考虑了另一个被广泛接受的道德责任条件:认识论条件。本文所捍卫的观点是,对于BPD个体的责任问题的答案,既涉及控制条件,也涉及认识条件,取决于对他们的认识概况的理解。
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引用次数: 0
Bodies as communication systems. The relevance of Michel Serres's philosophy of science for health care. 身体作为交流系统。米歇尔·塞雷斯的医疗保健科学哲学的相关性。
IF 2.3 2区 哲学 Q1 ETHICS Pub Date : 2024-12-26 DOI: 10.1007/s11019-024-10244-5
Aldo Houterman

This article demonstrates the value of French philosophy of science for medical practice through an exposition of Michel Serres's philosophy of the body. It explores how Serres's examination of the similarity between scientific models and works of art can provide insight into different conceptions of the human body. What makes Serres's method of unique is that it does not see art and literature as subordinate to the natural sciences: they are both involved in mapping the communication lines of the body. Since early modernity, we can roughly speak of three successive communication models of the body: mechanical, thermodynamic and informational. This article finally discusses the relationship between those different conceptions and explains how they help to articulate different aspects of the body, health, and medical ethics.

本文通过对米歇尔·塞雷斯身体哲学的阐释,论证了法国科学哲学对医学实践的价值。它探讨了Serres对科学模型和艺术作品之间相似性的研究如何提供对人体不同概念的见解。Serres方法的独特之处在于,它没有将艺术和文学视为自然科学的附属:它们都涉及绘制身体的交流线路。从现代性早期开始,我们大致可以说身体的三种连续的交流模式:机械的、热力学的和信息的。本文最后讨论了这些不同概念之间的关系,并解释了它们如何有助于阐明身体、健康和医学伦理的不同方面。
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引用次数: 0
Correction: Conceptual scaffolding for the philosophy of medicine. 更正:医学哲学的概念框架。
IF 2.3 2区 哲学 Q1 ETHICS Pub Date : 2024-12-20 DOI: 10.1007/s11019-024-10242-7
Yael Friedman
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引用次数: 0
Endometriosis in later life: an intersectional analysis from the perspective of epistemic injustice. 晚年子宫内膜异位症:从认识不公正的角度进行交叉分析。
IF 2.3 2区 哲学 Q1 ETHICS Pub Date : 2024-12-20 DOI: 10.1007/s11019-024-10245-4
Elisabeth Langmann, Anna-Christina Kainradl, Merle Weßel, Alekszandra Rokvity

Endometriosis, a chronic inflammatory condition affecting 10% of biological women, is widely understudied and particularly overlooked in later life. Discussions surrounding endometriosis predominantly centre on medical gender bias during reproductive years, with limited attention to intersecting factors of discrimination and the impact of ageism on affected individuals. As endometriosis is framed as a disease of reproductive age, research is lacking when it comes to the effects of the illness on the older population. Symptoms in (post)menopausal individuals are frequently misattributed to other ailments due to ageist and sexist preconceptions, leading to prolonged diagnoses and mistreatment. This is a social justice issue in which age and sex contribute to the discrimination of a certain population - namely older biological women living with endometriosis. In this paper, we approach this issue from the perspective of epistemic justice. The experiences of the affected persons are shaped by a lack of knowledge about endometriosis among both the healthcare personal and the affected person, as well as a lack of acknowledgement and consideration of the persons experiences. Using the lens of epistemic justice, we develop an analytical model to understand the intersection of age and gender in the experiences of endometriosis patients. This article contributes to ongoing debates on epistemic injustice and intersectionality within medicine and healthcare, offering an analytical model that connects the critical approaches of epistemic injustice and intersectionality to address health injustice. Ultimately, this work advocates for a comprehensive, lifespan approach to endometriosis that acknowledges and addresses intersecting forms of discrimination.

子宫内膜异位症是一种慢性炎症性疾病,影响10%的生物学意义上的女性。围绕子宫内膜异位症的讨论主要集中在育龄期的医疗性别偏见上,很少关注歧视的交叉因素和年龄歧视对受影响个体的影响。由于子宫内膜异位症被认为是一种育龄疾病,因此缺乏有关该疾病对老年人影响的研究。由于年龄歧视和性别歧视的先入之见,绝经后个体的症状经常被误认为是其他疾病,导致长时间的诊断和虐待。这是一个社会公正问题,其中年龄和性别导致了对特定人群的歧视-即患有子宫内膜异位症的老年生物学妇女。在本文中,我们从认识正义的角度来探讨这个问题。受影响的人的经历是由于保健人员和受影响的人都缺乏对子宫内膜异位症的知识,以及缺乏对个人经历的承认和考虑而形成的。使用认知正义的镜头,我们开发了一个分析模型,以了解年龄和性别在子宫内膜异位症患者的经验的交集。本文有助于医学和医疗保健中关于认知不公正和交叉性的持续辩论,提供了一个分析模型,将认知不公正和交叉性的关键方法联系起来,以解决健康不公正问题。最终,这项工作提倡对子宫内膜异位症采取全面的、终身的方法,承认并解决交叉形式的歧视。
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引用次数: 0
Clouds on the horizon: clinical decision support systems, the control problem, and physician-patient dialogue. 地平线上的乌云:临床决策支持系统、控制问题和医患对话。
IF 2.3 2区 哲学 Q1 ETHICS Pub Date : 2024-12-07 DOI: 10.1007/s11019-024-10241-8
Mahmut Alpertunga Kara

Artificial intelligence-based clinical decision support systems have a potential to improve clinical practice, but they may have a negative impact on the physician-patient dialogue, because of the control problem. Physician-patient dialogue depends on human qualities such as compassion, trust, and empathy, which are shared by both parties. These qualities are necessary for the parties to reach a shared understanding -the merging of horizons- about clinical decisions. The patient attends the clinical encounter not only with a malfunctioning body, but also with an 'unhomelike' experience of illness that is related to a world of values and meanings, a life-world. Making wise individual decisions in accordance with the patient's life-world requires not only scientific analysis of causal relationships, but also listening with empathy to the patient's concerns. For a decision to be made, clinical information should be interpreted considering the patient's life-world. This side of clinical practice is not a job for computers, and they cannot be final decision-makers. On the other hand, in the control problem users blindly accept system output because of over-reliance, rather than evaluating it with their own judgement. This means over-reliant parties leave their place in the dialogue to the system. In this case, the dialogue may be disrupted and mutual trust may be lost. Therefore, it is necessary to design decision support systems to avoid the control problem and to limit their use when this is not possible, in order to protect the physician-patient dialogue.

基于人工智能的临床决策支持系统具有改善临床实践的潜力,但由于控制问题,它们可能对医患对话产生负面影响。医患对话依赖于人类的品质,如同情、信任和同理心,这些都是双方共有的。这些品质对于各方就临床决策达成共同理解——视野的融合——是必要的。患者参加临床治疗,不仅是一个功能失调的身体,而且还有一种“不像家一样”的疾病体验,这种体验与一个价值和意义的世界、一个生活世界有关。根据患者的生活世界做出明智的个人决定,不仅需要对因果关系进行科学分析,还需要同情地倾听患者的担忧。为了做出决定,临床信息应该考虑到患者的生活世界来解释。临床实践的这一方面不是计算机的工作,它们不能成为最终决策者。另一方面,在控制问题中,用户由于过度依赖而盲目接受系统输出,而不是用自己的判断对其进行评价。这意味着过度依赖的各方将自己在对话中的位置留给了系统。在这种情况下,对话可能会中断,互信可能会丧失。因此,有必要设计决策支持系统来避免控制问题,并在不可能的情况下限制其使用,以保护医患对话。
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引用次数: 0
One R or the other - an experimental bioethics approach to 3R dilemmas in animal research. 非此即彼--以实验生物伦理学方法解决动物研究中的 3R 困境。
IF 2.3 2区 哲学 Q1 ETHICS Pub Date : 2024-12-01 Epub Date: 2024-08-17 DOI: 10.1007/s11019-024-10221-y
Christian Rodriguez Perez, David M Shaw, Brian D Earp, Bernice S Elger, Kirsten Persson

Sacrificial dilemmas such as the trolley problem play an important role in experimental philosophy (x-phi). But it is increasingly argued that, since we are not likely to encounter runaway trolleys in our daily life, the usefulness of such thought experiments for understanding moral judgments in more ecologically valid contexts may be limited. However, similar sacrificial dilemmas are experienced in real life by animal research decision makers. As part of their job, they must make decisions about the suffering, and often the death, of many non-human animals. For this reason, a context-specific investigation of so-called "3R dilemmas" (i.e., dilemmas where there is a conflict between the principles of replacement, reduction, and refinement of the use of animals in research) is essential to improve the situation of both non-human animals and human stakeholders. An approach well suited for such investigation is experimental philosophical bioethics ("bioxphi"), which draws on methods similar to x-phi to probe more realistic, practical scenarios with an eye to informing normative debates and ethical policy. In this article, we argue for a need to investigate 3R dilemmas among professional decision-makers using the tools of bioxphi. In a first step, we define 3R dilemmas and discuss previous investigations of professionals' attitudes in such cases. In a second step, we show how bioxphi is a promising method to investigate the whys and hows of professional decision-making in 3R dilemmas. In a last step, we provide a bioxphi template for 3R dilemmas, give recommendations on its use, explore the normative relevance of data collected by such means, and discuss important limitations.

在实验哲学(x-phi)中,电车问题等牺牲性两难问题发挥着重要作用。但越来越多的人认为,由于我们在日常生活中不可能遇到失控的手推车,因此这种思想实验对于理解更生态化的道德判断的作用可能有限。然而,动物研究决策者在现实生活中也会遇到类似的牺牲困境。作为工作的一部分,他们必须对许多非人类动物的痛苦,甚至死亡做出决定。因此,针对具体情况调查所谓的 "3R 困境"(即在研究中使用动物的替代、减少和完善原则之间存在冲突的困境)对于改善非人类动物和人类利益相关者的处境至关重要。实验哲学生物伦理学("bioxphi")是一种非常适合此类研究的方法,它利用与 x-phi 类似的方法来探究更现实、更实际的情景,以期为规范性辩论和伦理政策提供信息。在本文中,我们认为有必要利用 bioxphi 工具调查专业决策者的 3R 困境。首先,我们定义了 3R 困境,并讨论了以往对专业人员在此类情况下的态度所做的调查。第二步,我们将展示 bioxphi 如何成为研究 3R 困境中专业决策的原因和方法的一种有前途的方法。最后,我们为 3R 困境提供了一个 bioxphi 模板,就其使用提出了建议,探讨了通过这种方法收集的数据的规范相关性,并讨论了重要的局限性。
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引用次数: 0
Genetic enhancement from the perspective of transhumanism: exploring a new paradigm of transhuman evolution. 从超人主义的角度看基因强化:探索超人进化的新范式。
IF 2.3 2区 哲学 Q1 ETHICS Pub Date : 2024-12-01 Epub Date: 2024-08-28 DOI: 10.1007/s11019-024-10224-9
Yawen Zou

Transhumanism is a movement that advocates for the enhancement of human capabilities through the use of advanced technologies such as genetic enhancement. This article explores the definition, history, and development of transhumanism. Then, it compares the stance on genetic enhancement from the perspectives of bio-conservatism, bio-liberalism, and transhumanism. This article posits that transhuman evolution has twofold implications, allowing for the integration of transhumanist research and evolutionary biology. First, it offers a compelling scientific framework for understanding genetic enhancement, avoiding technological progressivism, and incorporating concepts of evolutionary biology. Second, it represents a new evolutionary paradigm distinct from traditional Lamarckism and Darwinism. It marks the third synthesis of evolutionary biology, offering fresh perspectives on established concepts such as artificial selection and gene-culture co-evolution. In recent decades, human enhancement has captivated not only evolutionary biologists, neurobiologists, psychologists, and philosophers, but also those in fields such as cybernetics and artificial intelligence. In addition to genetic enhancement, other human enhancement technologies, including brain-computer interfaces and brain uploading, are currently under development, which the paradigm of transhuman evolution can better integrate into its framework.

超人类主义是一场运动,主张通过使用基因强化等先进技术来提高人类的能力。本文探讨了超人类主义的定义、历史和发展。然后,文章从生物保守主义、生物自由主义和超人类主义的角度比较了对基因强化的立场。本文认为,超人类进化论具有双重意义,可以将超人类主义研究与进化生物学结合起来。首先,它为理解基因强化提供了一个令人信服的科学框架,避免了技术进步主义,并纳入了进化生物学的概念。其次,它代表了一种新的进化范式,有别于传统的拉马克主义和达尔文主义。它标志着进化生物学的第三次综合,为人工选择和基因-文化共同进化等既定概念提供了全新的视角。近几十年来,人类增强不仅吸引了进化生物学家、神经生物学家、心理学家和哲学家,也吸引了控制论和人工智能等领域的学者。除基因强化外,其他人类强化技术,包括脑机接口和大脑上传,目前也在开发之中,超人类进化范式可以更好地将这些技术纳入其框架之中。
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引用次数: 0
What is a cure through gene therapy? An analysis and evaluation of the use of "cure". 什么是通过基因疗法治愈疾病?对使用 "治愈 "一词的分析和评价。
IF 2.3 2区 哲学 Q1 ETHICS Pub Date : 2024-12-01 Epub Date: 2024-08-22 DOI: 10.1007/s11019-024-10223-w
Lieke Baas, Karina Meijer, Annelien L Bredenoord, Rieke van der Graaf

The development of gene therapy has always come with the expectation that it will offer a cure for various disorders, of which hemophilia is a paradigm example. However, although the term is used regularly, it is unclear what exactly is meant with "cure". Therefore, the aim of this paper is to analyse how the concept of cure is used in practice and evaluate which of the interpretations is most suitable in discussions surrounding gene therapy. We analysed how cure is used in four different medical fields where the concept raises discussion. We show that cure can be used in three different ways: cure as normalization of the body, cure as obtaining a normal life, or cure as a change in identity. We argue that since cure is a practical term, its interpretation should be context-specific and the various uses can exist simultaneously, as long as their use is suitable to the function the notion of cure plays in each of the settings. We end by highlighting three different settings in the domain of hemophilia gene therapy in which the term cure is used and explore the function(s) it serves in each setting. We conclude that in the clinical application of gene therapy, it could be better to abandon the term cure, whereas more modest and specified definitions of cure are required in the context of health resource allocation decisions and decisions on research funding.

基因疗法的发展总是伴随着人们对治愈各种疾病的期望,血友病就是其中的一个典型例子。然而,尽管这一术语经常被使用,但 "治愈 "的确切含义却并不明确。因此,本文旨在分析 "治愈 "这一概念在实践中是如何使用的,并评估在围绕基因疗法的讨论中哪种解释最合适。我们分析了 "治愈 "这一概念在引发讨论的四个不同医学领域的使用情况。我们发现,"治愈 "有三种不同的用法:"治愈 "是指身体恢复正常;"治愈 "是指获得正常生活;"治愈 "是指身份的改变。我们认为,既然 "治愈 "是一个实用的术语,那么对它的解释就应根据具体语境而定,而且各种用法可以同时存在,只要它们的使用适合 "治愈 "概念在每种环境中所发挥的功能即可。最后,我们强调了血友病基因治疗领域中使用治愈一词的三种不同情况,并探讨了治愈在每种情况下的功能。我们的结论是,在基因疗法的临床应用中,最好放弃治愈一词,而在医疗资源分配决策和研究经费决策中,则需要对治愈进行更适度、更具体的定义。
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引用次数: 0
The role of conscience and virtue: contrasting two models of medicine. 良知与美德的作用:两种医学模式的对比。
IF 2.3 2区 哲学 Q1 ETHICS Pub Date : 2024-12-01 Epub Date: 2024-10-01 DOI: 10.1007/s11019-024-10229-4
Jaime Hernandez-Ojeda, Xavier Symons

Today's medical ethics involve two different viewpoints based on how we understand the role of conscience in medicine and the purpose of healthcare. The first view, called the health-directed model, sees medicine as a way to improve health and promote healing, while also respecting the values of both patients and doctors. In this model, doctors need some discretionary space to decide how to achieve the best health outcomes in their practice. On the other hand, the service-provider model sees the main goal of medicine as providing a service, especially healthcare, with a strong focus on protecting patient autonomy. In this view, doctors are required to provide care even when it goes against their personal beliefs.The goal of this article is to explore the foundations and arguments of these two medical models. Understanding the key ideas behind these models is important for deciding whether to support or oppose conscientious objection in medical ethics. Additionally, the article aims to figure out which model makes a stronger case and to offer advice on how to engage with the opposing view from a virtue ethics perspective.

当今的医学伦理涉及两种不同的观点,它们基于我们如何理解良知在医学中的作用以及医疗保健的目的。第一种观点被称为 "健康导向模式"(health-directed model),认为医学是改善健康和促进治疗的一种方式,同时也尊重患者和医生的价值观。在这种模式下,医生需要一定的自由空间来决定如何在诊疗过程中实现最佳的医疗效果。另一方面,服务提供者模式认为医学的主要目标是提供服务,尤其是医疗保健服务,重点是保护病人的自主权。本文旨在探讨这两种医学模式的基础和论点。了解这两种模式背后的主要观点,对于决定在医学伦理中支持还是反对依良心拒服兵役非常重要。此外,文章还旨在找出哪种模式更有说服力,并就如何从美德伦理学的角度与对立观点打交道提出建议。
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引用次数: 0
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