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Recurrence Patterns of Odontogenic Keratocysts in Syndromic and Non-Syndromic Patients. 综合征和非综合征患者牙源性角化囊肿的复发模式
IF 0.9 Q2 Dentistry Pub Date : 2024-02-01 Epub Date: 2023-04-24 DOI: 10.1007/s12663-023-01920-9
Tim Van Cleemput, Xander Jackers, Maria Piagkou, Constantinus Politis

Purpose: Odontogenic keratocysts (OKCs) have high recurrence rates. We aimed to identify recurrence patterns in OKCs and the onset of second primary OKCs in non-syndromic and syndromic patients.

Material and methods: Patients with OKCs reporting to our department from 1998 to 2021 (23 years) were retrospectively evaluated using demographic, clinical (age, sex, location, and size), histopathological, radiographic, and treatment data. All patients were followed-up for > 3 years and evaluated for OKC recurrence. Patients with naevoid basal cell carcinoma syndrome (NBCCS) were evaluated separately.

Results: We included 38 and 13 patients in the non-syndromic and syndromic OKC groups, respectively. The recurrence rates were 15.8 and 21.4% in the non-syndromic and syndromic groups, respectively; 8.9% of patients exhibited a second recurrence and 1.8% a third recurrence. No second primary OKCs were observed in the non-syndromic group; 76.9% of patients in the syndromic group developed at least one.

Conclusion: We found a higher recurrence rate in patients with NBCCS compared with patients with non-syndromic OKCs (21.4 versus 15.8%). The probability of developing a second primary OKC in patients with NBCCS was higher compared with that in patients with non-syndromic OKCs (76.9 versus 0%). No statistically significant risk factors for OKC recurrence were identified.

目的:牙源性角囊肿(OKCs)的复发率很高。我们旨在确定OKC的复发模式,以及非综合征和综合征患者中第二原发性OKC的发病情况:我们使用人口统计学、临床(年龄、性别、位置和大小)、组织病理学、放射学和治疗数据,对 1998 年至 2021 年(23 年)向我科报告的 OKC 患者进行了回顾性评估。所有患者均接受了 3 年以上的随访,并对 OKC 复发情况进行了评估。对患有无色素性基底细胞癌综合征(NBCCS)的患者进行了单独评估:我们在非综合征和综合征 OKC 组中分别纳入了 38 名和 13 名患者。非综合征组和综合征组的复发率分别为 15.8% 和 21.4%;8.9% 的患者第二次复发,1.8% 的患者第三次复发。非综合征组中没有观察到第二个原发性 OKC,而综合征组中 76.9% 的患者至少出现了一个原发性 OKC:我们发现,与非综合征 OKCs 患者相比,NBCCS 患者的复发率更高(21.4% 对 15.8%)。与非综合征 OKC 患者相比,NBCCS 患者再次发生原发性 OKC 的概率更高(76.9% 对 0%)。没有发现具有统计学意义的 OKC 复发风险因素。
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引用次数: 0
Injury to the Submandibular Duct and Secondary Fibrosis Causing Sialocele: An Unusual Complication of Submental Intubation. 下颌下管损伤和继发性纤维变性引起Sialocele:一种罕见的颏下插管并发症
IF 0.9 Q2 Dentistry Pub Date : 2024-02-01 Epub Date: 2022-08-22 DOI: 10.1007/s12663-022-01773-8
Nidhi Bhatia, Tarush Gupta, Sourabha Patro, S P S Aswin Ram, Dias Queenie Valerian, Kajal Jain

Maxillofacial fractures with the nasal/skull base fractures may preclude nasotracheal intubation, and oro-tracheal intubation may obstruct surgical access. In these cases, submental intubation is a safe and well-accepted alternative, associated with low morbidity and complication rate. We report a case of one such rare complication, wherein following submental intubation, the patient presented with a sublingual sialocele, associated with dilatation of the submandibular duct with surrounding fibrosis. The secondary sublingual sialocele we encountered could have been due to errors in the technique of submental intubation. Hence, thorough knowledge of the submental and submandibular region's anatomy is important to avoid complications.

颌面部骨折伴有鼻骨/颅底骨折可能会妨碍鼻气管插管,而口气管插管可能会阻碍手术通道。在这些情况下,门下插管是一种安全且广为接受的替代方法,发病率和并发症发生率都很低。我们报告了一例此类罕见并发症的病例,患者在门下插管后出现舌下咽峡炎,伴有颌下腺导管扩张和周围纤维化。我们遇到的继发性舌下咽峡炎可能是由于下颌插管技术错误造成的。因此,全面了解下颌下和颌下腺区域的解剖结构对于避免并发症非常重要。
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引用次数: 0
Comparison of Five Different Treatment Approaches of Mandibular Keratocystic Odontogenic Keratocyst (OKC): A Retrospective Recurrence Analysis of Clinical and Radiographic Parameters. 下颌角化囊性牙源性角化囊肿(OKC)五种不同治疗方法的比较:临床和影像学参数的回顾性复发分析
IF 0.9 Q2 Dentistry Pub Date : 2024-02-01 Epub Date: 2023-06-21 DOI: 10.1007/s12663-023-01929-0
Henriette L Moellmann, Aida Parviz, Marcia Goldmann-Kirn, Madiha Rana, Majeed Rana

The odontogenic keratocyst (OKC) is a benign but locally aggressive growing lesion that infiltrates the bone and surrounding tissue. It is characterized by high rates of recurrence along with rapid growth. Different forms of partly successful treatment therapies are reported. The retrospective study at hand examined 114 patients with OKC treated over a period of 20 years. Data extracted includes gender, age, location, previous treatment for the lesion, surgery, outcome, recurrence rate and follow-up. 63.1% of the patients underwent cystectomy, 22.5% by cystectomy and carnoy solution, 7.2% by cystectomy, and curettage, 4.5% by cystostomy and 2.7% by partial resection. In this study, no significant differences could be observed regarding the surgical method. Most recurrences occurred with 91.9% in the mandible with an average size of 5.5 cm2 and increased in women. Within a mean follow-up time of 3.6 years the recurrence rate was 36.9%, on average after 36 months. Recurrences were most frequently diagnosed at the age of 31-50 (43.9%). Despite numerous studies, there is still no unanimous opinion on an effective therapy for OKC. However, precise resection of OKC can be facilitated by preoperative 3D-imaging and virtual planning.

牙源性角化囊肿(OKC)是一种良性但局部侵袭性生长的病变,会浸润骨骼和周围组织。其特点是复发率高且生长迅速。据报道,有不同形式的治疗方法取得了部分成功。本项回顾性研究对 114 名接受过 20 年治疗的 OKC 患者进行了调查。提取的数据包括性别、年龄、病变部位、之前的治疗方法、手术、结果、复发率和随访情况。63.1%的患者接受了膀胱切除术,22.5%的患者接受了膀胱切除术和卡诺溶液,7.2%的患者接受了膀胱切除术和刮宫术,4.5%的患者接受了膀胱造口术,2.7%的患者接受了部分切除术。在这项研究中,手术方法没有明显差异。大多数复发(91.9%)发生在下颌骨,平均大小为 5.5 平方厘米,女性复发率更高。在平均 3.6 年的随访时间内,复发率为 36.9%,平均在 36 个月后复发。复发年龄多在 31-50 岁之间(43.9%)。尽管进行了大量的研究,但对于 OKC 的有效治疗方法仍然没有一致的意见。不过,术前三维成像和虚拟规划可以帮助精确切除 OKC。
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引用次数: 0
A Large Follicular Dentigerous Cyst: A New Multi-portal Access: Intraoral and Endoscopic Technique. 一种新的多门入路:口腔内和内镜技术
IF 0.9 Q2 Dentistry Pub Date : 2024-02-01 Epub Date: 2023-03-14 DOI: 10.1007/s12663-023-01885-9
A Romano, G Norino, G Dell'Aversana Orabona, S Barone, D Ordano, C Calvanese, S Troise, L Califano, G Iaconetta

Background: The standard treatment for a dentigerous cyst of maxilla is a surgical enucleation, the extraction of the tooth. In the case of cysts involving the maxillary sinus, a Caldwell-Luc approach is used. In case of large cysts, its marsupialization is carried out in order to reduce the bone defect, followed by enucleation and extraction of the tooth.

Methods: This is a case of a large follicular dentigerous cyst of upper jaw with 18 ectopic tooth within the maxillary sinus, treated in our Unit.

Results: We decided to perform a multi-portal access, the intraoral endoscopic-assisted technique; an intraoral approach has been performed, but less demolishing than the routine intraoral approach, through the anterior wall of the maxillary sinus, already eroded by the lesion. The lesion was very large, occupying the entire maxillary cavity. For this reason, by means of the intraoral approach alone, it was extremely difficult to remove the lesion in its entirety. The endoscopic-assisted technique was combined with intraoral approach. The lesion extended to the maxillary ostium. This did not allow to reach the ostium through the classic endoscopic approach. Endonasal endoscopic access was used both to enucleate the cyst, that was adherent to the orbital floor and soft tissues of the OMC (osteomeatal complex), and to restore the physiological drainage of the maxillary sinus.

Conclusions: We decided to perform a combined intraoral and endoscopic approach to allow a complete excision of the cystic lesion, without being very demolishing and taking advantage of the bone erosion already caused by the large cyst.

背景:上颌齿槽囊肿的标准治疗方法是手术切除,即拔除牙齿。如果囊肿涉及上颌窦,则采用 Caldwell-Luc 方法。在囊肿较大的情况下,则要进行髓核摘除术,以减少骨缺损,然后再进行髓核摘除术和拔牙:这是一例上颌大滤泡性齿槽囊肿病例,上颌窦内有 18 颗异位牙:我们决定采用多孔口腔内窥镜辅助技术;口腔内入路,但与常规口腔内入路相比,通过已被病变侵蚀的上颌窦前壁,破坏性较小。病变非常大,占据了整个上颌窦腔。因此,仅靠口腔内入路极难完整切除病灶。内窥镜辅助技术与口腔内入路相结合。病变延伸至上颌骨骨膜。这使得传统的内窥镜方法无法到达骨膜。口腔内窥镜入路既可以将粘附在眶底和OMC(骨产道复合体)软组织上的囊肿去核,又可以恢复上颌窦的生理性引流:我们决定采用口腔内和内窥镜联合手术的方式,以便彻底切除囊肿病灶,同时又不会造成严重破坏,还能利用大囊肿已经造成的骨侵蚀。
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引用次数: 0
Use of Sodium Hyaluronate and Triamcinolone Acetonide Following Arthrocentesis in Treatment of Internal Derangement of Temporomandibular Joint: A Prospective Randomized Comparative Study. 关节穿刺术后透明质酸钠和曲安奈德治疗颞下颌关节内紊乱的前瞻性随机对照研究
IF 0.9 Q2 Dentistry Pub Date : 2024-02-01 Epub Date: 2022-10-07 DOI: 10.1007/s12663-022-01804-4
Ravina Dharamsi, Kumar Nilesh, C D Mouneshkumar, Pankaj Patil

Background: Internal derangement (ID) of temporomandibular joint (TMJ) is a common temporomandibular disorder (TMD) which causes hypomobility of the joint. Minimally invasive treatment modality like arthrocentesis is used as first-line of management having low morbidity and high efficacy. This prospective randomized comparative study was carried to compare the efficacy of intra-articular injection with sodium hyaluronate (SH) and triamcinolone acetonide (TA) after arthrocentesis in ID of TMJ.

Materials and methods: A total 40 patients diagnosed with ID (stage 1-4) were included in the study and randomly divided in two groups. Twenty patients (group A) received intra-articular injection of SH while 20 patients (group B) received intra-articular injection of TA, after arthrocentesis. The clinical parameters of pain (VAS), Maximum mouth opening (MMO) (mm) and clicking sound (present/absent) were evaluated pre-operatively and at seventh day, 1 month and 3 months post-operatively.

Results: There was statistically significant improvement in pain scores in both the groups at all time intervals with SH being superior (p value 0.0086). All the patients showed improved mouth opening at all time intervals, TA being superior but statistically insignificant (p value 0.59). There was reduction in the clicking sound in both the groups which was statistically insignificant at all time intervals.

Conclusions: Arthrocentesis followed by intra-articular injection with SH is superior to TA in terms of pain reduction, while TA showed superiority in terms of improved mouth opening.

背景:颞下颌关节(TMJ)内错位(ID)是一种常见的颞下颌关节疾病(TMD),会导致关节活动度减低。关节腔穿刺术等微创治疗方式被作为一线治疗方法,具有发病率低、疗效高的特点。这项前瞻性随机比较研究旨在比较关节腔穿刺术后关节内注射透明质酸钠(SH)和曲安奈德(TA)治疗颞下颌关节紊乱症的疗效:研究共纳入 40 名确诊为 ID(1-4 期)的患者,并将其随机分为两组。20 名患者(A 组)在关节穿刺术后接受 SH 的关节内注射,20 名患者(B 组)接受 TA 的关节内注射。术前、术后第七天、1 个月和 3 个月对疼痛(VAS)、最大张口度(MMO)(毫米)和咔嗒声(有/无)等临床参数进行评估:在所有时间间隔内,两组患者的疼痛评分均有明显改善,其中 SH 组更优(P 值为 0.0086)。所有患者在各时间段的张口情况均有所改善,TA 组较好,但无统计学意义(P 值 0.59)。两组患者的咔嗒声均有所减少,但在所有时间间隔内均无统计学意义:结论:关节穿刺术后关节内注射SH在减轻疼痛方面优于TA,而TA在改善张口方面更胜一筹。
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引用次数: 0
A Finite Element Analysis of Single, Double & Matrix Miniplate in Fracture of the Mandibular ANGLE Region: An In Vitro Study. 单、双、基质微型钢板在下颌角区骨折中的有限元分析
IF 0.9 Q2 Dentistry Pub Date : 2024-02-01 Epub Date: 2022-09-30 DOI: 10.1007/s12663-022-01799-y
Akshaya Subramanian, B M Rudagi, Puja Londhe, Chinmayee Palande

Purpose: To evaluate and compare the efficacy of three osteosynthesis systems in fixation of mandibular angle fractures using Finite Element Analysis.

Materials and methods: In this study, we used a three-dimensional finite element analysis to assess the stress, deformation and strain in three different groups with bite force loads. A three-dimensional finite element model of the mandible with three different plating techniques using modelling software 'Solidworks2018' and was analysed for stress, deformation and strain produced in the bone following biting loads of different magnitude using analysing software 'ANSYS Workbench'.

Results: In this study, we found out that the tensile forces in the matrix miniplate with vertical struts were well distributed in the cortical and cancellous bone on comparison with other two fixation systems in fixation of the mandibular angle fracture and therefore prevents lateral displacement, torsion and bending. The matrix miniplate system revealed less displacement of the fracture segments as compared to the other two plating systems.

Conclusion: The use of matrix miniplate for the treatment of mandibular angle fractures can be considered efficacious. The stress transferred onto the cortical & cancellous bone is least in the matrix plate leading to better stability of the fixation system.

目的:利用有限元分析评估和比较三种骨合成系统在下颌角骨折固定中的功效:在本研究中,我们使用三维有限元分析评估了三组不同咬合力载荷下的应力、变形和应变。使用建模软件 "Solidworks2018 "建立了三种不同电镀技术的下颌骨三维有限元模型,并使用分析软件 "ANSYS Workbench "分析了不同大小的咬合力载荷在骨骼中产生的应力、变形和应变:在这项研究中,我们发现在固定下颌角骨折时,与其他两种固定系统相比,带有垂直支柱的基质小板的拉力在皮质骨和松质骨中分布良好,因此可以防止侧向位移、扭转和弯曲。与其他两种固定系统相比,基质小钢板系统显示骨折段的移位较少:结论:使用基质微型钢板治疗下颌角骨折是有效的。基质小钢板转移到皮质骨和松质骨上的应力最小,因此固定系统的稳定性更好。
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引用次数: 0
Anatomical Analysis of Inferior Alveolar Nerve Relation to Mandibular Posterior Teeth Using Cone Beam Computed Tomography: A Retrospective Radiographic Analysis Study. 下牙槽神经与下颌后牙关系的锥形束计算机断层解剖分析:回顾性影像学分析研究
IF 0.9 Q2 Dentistry Pub Date : 2024-02-01 Epub Date: 2022-09-23 DOI: 10.1007/s12663-022-01792-5
Yasser Nabil El Hadidi, Alyaa Mahmoud Ahmed Taha, Shaimaa Mohamed Abu El Sadat, Shehabeldin Mohamed Saber

Introduction: Cone beam computed tomography (CBCT) is reliable in the assessment of structures related to teeth. The assessment of the inferior alveolar neurovascular (IAN) bundle location using CBCT is considered one of its prime uses in different mandibular surgeries.

Methodology: Retrospective CBCT data of patients presented to the institute were assessed to measure relations of IAN. Measurements were taken to assess the bone thickness adjacent to IAN, the superior-inferior dimension between the canal and the teeth, and the dimension between the canal and the inferior border of the mandible.

Results: Out of the 170 patients the root apices nearest to the IAN were that of the second molars (1.76 ± 1.86 mm). The IAN was closest to the inferior border of the mandible at the roots of the second molars (8 ± 3.4 mm). The buccal bone thickness had its greater dimension buccal to the IAN at the area of the second molar (5.16 ± 1.26 mm).

Conclusion: Two mini-plates in trauma do not increase the risk of injury. It is advisable in apicectomy not to extend 1.5 mm apically. The thickness of the nerve-lateralization window should not exceed 2 mm. In body osteotomy procedure, perform surgery anterior to premolars as much as possible.

简介锥形束计算机断层扫描(CBCT)是评估牙齿相关结构的可靠方法。使用 CBCT 评估下牙槽神经血管束(IAN)的位置被认为是其在不同下颌骨手术中的主要用途之一:方法:对到该研究所就诊的患者的 CBCT 数据进行回顾性评估,以测量 IAN 的关系。测量结果用于评估 IAN 附近的骨厚度、根管与牙齿之间的上下尺寸以及根管与下颌骨下缘之间的尺寸:在 170 名患者中,离 IAN 最近的根尖是第二磨牙的根尖(1.76 ± 1.86 mm)。第二磨牙根部的 IAN 最接近下颌骨下缘(8 ± 3.4 毫米)。颊骨厚度在第二磨牙区域的 IAN 颊侧最大(5.16 ± 1.26 mm):结论:在创伤中使用两个迷你板不会增加损伤风险。在进行根尖切除术时,最好不要向根尖延伸 1.5 毫米。神经侧窗的厚度不应超过 2 毫米。在体部截骨术中,尽可能在前磨牙前方进行手术。
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引用次数: 0
To Evaluate the Efficacy of Biomarkers as Monitoring Tool in Patients with Fascial Space Infections of Odontogenic Origin: A Clinical Study. 评价生物标志物作为牙源性筋膜间隙感染患者监测工具的疗效:一项临床研究
IF 0.9 Q2 Dentistry Pub Date : 2024-02-01 Epub Date: 2022-05-07 DOI: 10.1007/s12663-022-01722-5
Mehak Malhotra, Tejinder Kaur, Sahiba Kukreja, Ramandeep Singh Bhullar, Amit Dhawan, Amneet Sandhu

Introduction: The objective was to evaluate the efficacy of biochemical markers (WBC, CRP and fibrinogen) and the course of odontogenic space infections in 50 patients.

Material and methods: Blood samples were taken preoperatively and postoperatively at day 0, day 4, day 8 and day 12 for measuring the levels of all three biomarkers. The trends of the biomarkers were observed and compared with assessment parameters such as dental etiology, number of teeth involved, number of spaces involved, mouth opening and pain. Active pus discharge, dysphagia, hoarseness and swelling were assessed and scored accordingly.

Results: The data were subjected to paired 't' test, McNemar's and Pearson's bivariate correlation as appropriate. Statistical analysis found strong correlation between laboratory values of markers and parameters used to measure severity of infection. All three biomarkers (WBC, CRP and fibrinogen) are significant markers for hospital stay (p < 0.01). Prospective analysis indicates that only one biomarker cannot be used to rule out specific diagnosis.

Conclusion: The combination of three biochemical markers assessed in the present study (WBC, CRP and fibrinogen) should be used as prognostic factor in assessment, clinical severity and efficacy of treatment regime for patients as these can reliably predict the clinical course of odontogenic infection.

引言目的是评估生化指标(白细胞、CRP和纤维蛋白原)的疗效以及50名患者牙源性间隙感染的过程:术前和术后分别在第 0 天、第 4 天、第 8 天和第 12 天采集血样,测量所有三种生物标志物的水平。观察生物标志物的变化趋势,并将其与牙科病因、受累牙齿数量、受累牙间隙数量、张口度和疼痛等评估参数进行比较。对活动性脓性分泌物、吞咽困难、声音嘶哑和肿胀进行评估和相应评分:对数据酌情进行配对 "t "检验、McNemar's 检验和 Pearson's 双变量相关检验。统计分析发现,实验室指标值与用于衡量感染严重程度的参数之间存在很强的相关性。所有三种生物标志物(白细胞、CRP 和纤维蛋白原)都是住院时间的重要标志物(P < 0.01)。前瞻性分析表明,仅用一种生物标志物不能排除特定的诊断:本研究中评估的三种生化标志物(白细胞、CRP 和纤维蛋白原)的组合应作为预后因素,用于评估患者的临床严重程度和治疗方案的疗效,因为这些标志物可以可靠地预测牙源性感染的临床过程。
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引用次数: 0
Bilateral Tunnelized FAMM Islanded Flap for Reconstruction of Composite Defect of Tongue and Floor of Mouth: A Case Report. 双侧隧道状FAMM岛状皮瓣修复舌底复合缺损1例
IF 0.9 Q2 Dentistry Pub Date : 2024-02-01 Epub Date: 2021-07-25 DOI: 10.1007/s12663-021-01624-y
Swagnik Chakrabarti, Abhishek Ghosh, Sandeep Bhukkar, Aseem Mishra

The work of Massarelli et al. is well known for popularizing t-FAMMIF, however to the best of our knowledge bilateral flap has never been harvested and inset together to reconstruct a composite defect. Larger unilateral flaps have been reported in literature but to harvest such a flap in patients of S.E Asian region would entail high propensity for trismus in the post op period as they have tendency for submucosal fibrosis owing to their guthka (chewing tobacco) chewing habits. Oral submucous fibrosis is contra-indication for this flap; however, some of our patients despite being chronic abusers of guthka do not have clinical presentation of OSMF and if the defect post ablation is appropriate are chosen to be candidates for reconstruction with the flap. In this select population harvesting larger flaps can potentially lead to trismus, a fact highlighted in the paper.

Massarelli等人的研究成果因推广t-FAMMIF而广为人知,但就我们所知,从未有人将双侧皮瓣采集并嵌入一起重建复合缺损。文献中曾报道过较大的单侧皮瓣,但如果在东南亚地区的患者身上采集这样的皮瓣,术后很容易出现三期畸形,因为他们有咀嚼烟草的习惯,容易造成粘膜下纤维化。口腔黏膜下纤维化是该皮瓣的禁忌症;然而,我们的一些患者尽管长期咀嚼烟草,但并没有口腔黏膜下纤维化的临床表现,如果消融后缺损合适,他们就会被选为使用该皮瓣进行重建的候选者。在这些特定人群中,采集较大的皮瓣可能会导致三体症,这也是论文中强调的事实。
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引用次数: 0
Subcranial Approach for Management of Secondary Frontal Bone Deformity. 颅下入路治疗继发性额骨畸形
IF 0.9 Q2 Dentistry Pub Date : 2024-02-01 Epub Date: 2021-01-31 DOI: 10.1007/s12663-021-01518-z
Adarsh Kudva, Sunil Upadhyaya, Rajesh Nair

Abstract: Secondary correction for aesthetic purposes can be more challenging as the fractured segments may be united in abnormal positions and would require osteotomy procedures before mobilizing the segments for reconstruction. Such maneuvers require adequate exposure and visibility. The subcranial approach is an effective alternate to classical approaches, which required frontal lobe retraction.

Conclusion: Subcranial approach is a viable alternative to posttraumatic deformity of frontal bone.

摘要:以美观为目的的二次矫正可能更具挑战性,因为骨折节段可能在异常位置结合在一起,需要先进行截骨手术,然后再移动节段进行重建。此类手术需要足够的暴露和可见度。颅下入路是传统入路的有效替代方法,传统入路需要牵开额叶:结论:颅下入路是额骨外伤后畸形的可行替代方法。
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引用次数: 0
期刊
Journal of Maxillofacial & Oral Surgery
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