Journal of Maxillofacial & Oral Surgery最新文献

Introduction: The 'progression model' of oral carcinogenesis emphasizes that initial irreversible genotypic damage produces tissue disorganization and dysmaturation which, if allowed to progress, leads invariably towards invasive oral squamous cell carcinoma. Recognition of these genotypic changes is fundamental for a successful management strategy. Genetic studies have confirmed the role of pro-carcinogens present in tobacco and alcohol contributing to DNA damage and genotoxicity. Many molecular epidemiological studies have evaluated the association of head and neck cancer with polymorphisms in DNA repair genes. Our study aimed to investigate the association between single nucleotide polymorphisms (SNPs) of DNA repair genes OGG1 Ser326Cys, APE1-Asp148Glu, XRCC1- Arg194Trp, XRCC1-Arg280His, XRCC1-Arg399Gln, ADPRT-V762A, APEX1-D148E, LIG3-R780H, MUTYH-Tyr165Cys and the risk of oral squamous cell carcinoma and oral precancerous lesions.

Materials and method: Our study included two patient groups. Group I (n = 58) included patients with leukoplakia, oral submucous fibrosis and biopsy-proven oral squamous cell carcinoma. Group II (n = 58) included patients who had no clinically detectable lesions. Patients in both groups had tobacco chewing and smoking history. Blood samples were collected, and gene polymorphisms were identified using PCR-RFLP technique.

Results and discussion: Our study results revealed a statistically significant association between gene polymorphisms OGG1-Ser326Cys (p = 0.008), XRCC1-Arg194Trp (p = 0.009), XRCC1-Arg399Gln (p < 0.001), APEX1-Asp148Glu (p < 0.001) and the occurrence of leukoplakia, OSMF and OSCC.

Purpose: To propose a novel and viable modality for guarding an isolated zygomatic arch fracture following reduction in the initial postoperative phase.

Method: A silicone non-invasive ventilation mask is used efficiently as a guard during the initial postoperative period following reduction of an isolated zygomatic arch fracture.

Results: The use of a non-invasive ventilation mask as a guard is safe and versatile. However, it can be employed only in clinical situations where there are no other associated injuries or fractures of the facial skeleton.

Conclusion: The non-invasive ventilation mask is easy to use, less traumatic to the patient in addition to the fact that it aids in guarding an isolated zygomatic arch fracture following reduction during the initial postoperative phase.

Bone augmentation procedures are a crucial component of modern dental implantology enabling the restoration of adequate bone volume and soft tissue quality to support a successful implant placement. This review aims to provide a comprehensive analysis of the current techniques employed in bone augmentation, the scientific evidence substantiating their efficacy and the outcomes of these procedures in implantology.

Tooth extraction requires techniques that minimize tissue damage, yet alveolar bone fracture remains a common complication. The complexity increases when extracting mandibular molars with compromised wall support. This technical note introduces a novel forceps that combines a thin cowhorn like beak with a conventional mandibular third molar beak, enabling secure furcation engagement and controlled force application. The design aims to simplify extractions of grossly decayed mandibular molars, minimize trauma, and improve ease of use for both novice and experienced clinicians, offering a potential atraumatic alternative to conventional methods.

Introduction: Scars on the hair-bearing mustache area can be cosmetically disfiguring and interfere with adult male cleft patients social lives. Mustache reconstruction animates a male face, provides confidence, and interrupts the cycle of self-pity, providing a sense of completion. The purpose of this study was to examine and evaluate hair regrowth in the mustache region after hair restoration utilizing follicular unit extraction and follicular unit transplant procedures in individuals with secondary cleft lip scars.

Materials and methods: This was a prospective, double-blind, randomized controlled trial included 40 male patients presenting with either unilateral or bilateral cleft lip scars. Patients were randomly assigned to one of two groups: follicular unit extraction or follicular unit transplant. Macro Photographs were taken before surgery, as well as immediately after, 1, 3, 6, 9, and 12 months thereafter to evaluate the hair using the Madura et al. 10-point objective scale.

Results: At the end of the 1st month (p < 0.0001), 9th month (p < 0.0001), and 1 year (p < 0.0001), a statistically highly significant difference was observed between the compared groups, with higher values reported with the follicular unit extraction group at the 1st month (7.50 ± 1.581), 9th month (6.80 ± 1.229), and 1 year (7.50 ± 1.179). At the end of the 3rd month [p = 0.012] and 6th month [p = 0.002], a statistically significant difference was observed between the compared groups, with higher values reported with the follicular unit extraction group at the 3rd month (6.70 ± 1.337) and 6th month (7.20 ± 1.476).

Conclusion: The follicular unit extraction group has significantly better clinical changes and less adverse effects than the follicular unit transplant group.

Aims and objectives: The purpose of this study was to evaluate the size of the neck of mandibular condyle in Indian population using computed tomography (CT) scans and compare the same with that of hybrid plates.

Methods: A total of 172 mandibular condyles were studied which included both males and females belonging to age groups between 21 and 50 years. Independent sample t test was done for the comparison of condylar neck size between genders and comparing the same with that of size of miniplates.

Result: The average width of condylar neck in the most constricted region was 7.28 ± 1.38 mm ranging from 3.93 to 11.22 mm. Average condylar base width was 17.36 ± 1.44 mm ranging from 11.79 to 22.37 mm. All the hybrid plates except the trapezoidal plate were narrower than the average condylar neck dimensions. No significant difference was found in average condylar neck length and width between males and females.

Conclusion: In majority of cases of condylar neck fracture, fixation using two four holed with gap miniplates may not be possible; however, a hybrid plate can be used. Plates with width of 4 mm at superior border and 12 mm at inferior border would be the widest plate that could be accommodated in all the mandibular condyles.

Background: Cleft lip and palate and the resulting morphologic and functional deficits can cause a great deal of distress to patients and their families. Cleft lip deformity not only affects the lip but also extends to the nose and maxillary, with the severity varying according to the degree of the cleft. The main goal of surgery is to reconstruct the anatomy. Symmetry is a critical factor in evaluating the success of cleft lip surgeries. The previous evaluation methods were preoperative and postoperative comparisons by various methods to evaluate symmetry and the results of the surgery, such as the patient's feeling, data measurement, and other methods. So far, there is no simple and effective method to perform evaluation during surgery.

Methods and materials: This study was carried out between 2023 and 2024 and involved 12 unilateral cleft lip patients. Antera 3D® (Miravex, Dublin, Ireland) is used for image acquisition and image analysis (depression, medium/large). The 3D photographs were taken before, after, and at any point during the procedure. Different colours are used to show elevations and depressions, avoiding interference from the naked eye and light. And it can display a comparison graph of any two points in time on the screen at the same time. It allows the surgeon to more accurately determine the extent of deformity correction.

Results: All patients completed the repair of nasolabial. The duration of the operation has not increased. The appearances of almost all the patients were significantly improved, and all the patients and their families were satisfied with the outcome of the operation.

Conclusions: The system of the Antera 3D® was reliable and was a suitable technique for lip and nose analysis at any point in time during the operation.

Introduction: Anterior maxillary subapical osteotomy (AMSO) followed by premaxillary advancement is an orthognathic surgical procedure which has been undertaken rather infrequently in the recent past, owing to its being overtaken by premaxillary distraction osteogenesis (DO). It is most often employed in cleft cases with anteroposterior maxillary deficiency.

Material and methods: The procedure and technique of AMSO is also found to be amenable to modification, adaptation and incorporation as per specific requirements of individual cases. This case report describes its employment as an unusual and novel approach to treat a non-cleft maxillary deficiency case, as a case-specific technique.

Discussion: The report thereby attempts to re-popularize the procedure, by elaborating its ease, efficacy, reliability, predictability, expedient outcome as well as long-term stability in premaxillary advancements. It can offer several advantages in treating mild to moderate Skeletal Class III Dentofacial Disharmony cases with marked Anterior Crossbite & Reverse Overjet, with its novelty lying in simplicity and straightforwardness of the procedure; immediately apparent esthetic results post-surgery; with practically nil complication and relapse rates.

Results and conclusion: Its results, in terms of correction of both, the esthetic deformity and functional impairment (in speech and mastication), are almost immediately apparent. Additionally, it can be modified to a 'Surgery First, Orthodontics After (SFOA)' protocol, to further reduce the total treatment duration and yield a speedy outcome, which is of particular benefit in young adult patients with an active lifestyle, offering a distinct psychological advantage by an immediate improvement in facial appearance, enunciation as well as masticatory function. This facilitates a ready patient acceptance for treatment and also encourages optimal patient compliance during the post-surgical orthodontic phase.