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[DNVF Memorandum: Objectives and Methods of Physical Activity-Related Health Services Research]. [DNVF 备忘录:体育活动相关健康服务研究的目标和方法]。
IF 0.7 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-24 DOI: 10.1055/a-2340-1669
Lars Gabrys, Andrea Schaller, Stefan Peters, Anne Barzel, Susanne Berrisch-Rahmel, Karsten E Dreinhöfer, Katharina Eckert, Wiebke Göhner, Wolfgang Geidl, Sonja Krupp, Martin Lange, Roland Nebel, Klaus Pfeifer, Andrea Reusch, Matthias Schmidt-Ohlemann, Philipp Sewerin, Karen Steindorf, Andreas Ströhle, Gorden Sudeck, Hagen Wäsche, Sebastian Wolf, Bettina Wollesen, Christian Thiel

The DNVF Memorandum: Objectives and Methods of Physical Activity-Related Health Services Research summarizes, for the first time, the highly interdisciplinary and interprofessional field of physical activity-based health care in the German healthcare system. In addition to providing a conceptual framework and definition of key measures and concepts in physical activity-related health care research, existing research gaps and needs are identified, and methods for advancing this relatively young field of research are described. A particular focus of this study is the relevant outcome parameters and their standardized assessment using established and valid measurement tools. The memorandum aims to establish a general understanding of the complex subject of promoting physical activity and sports therapy in the context of healthcare, to give an impulse to new research initiatives, and to integrate the currently available strong evidence on the effectiveness of physical activity and exercise into healthcare.

DNVF 备忘录:与体育锻炼相关的医疗服务研究的目标和方法》首次总结了德国医疗保健系统中以体育锻炼为基础的医疗保健这一高度跨学科和跨专业的领域。除了提供概念框架和定义与体育锻炼相关的医疗保健研究的关键措施和概念外,还指出了现有的研究差距和需求,并介绍了推进这一相对年轻的研究领域的方法。本研究的一个特别重点是相关结果参数及其标准化评估,使用的是成熟有效的测量工具。本备忘录旨在建立对在医疗保健领域促进体育锻炼和运动疗法这一复杂课题的总体认识,推动新的研究计划,并将现有的关于体育锻炼和运动在医疗保健领域有效性的有力证据整合起来。
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引用次数: 0
Navigating the Future of Organisational Health Services Research in Germany and beyond: a Position Paper. 为德国及其他国家的组织保健服务研究的未来导航:立场文件》(Navigating the Future of Organisational Health Services Research in Germany and beyond: a Position Paper.
IF 0.7 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-22 DOI: 10.1055/a-2308-7384
Lena Ansmann, Stefan Nöst, Mirjam Körner, Carolin Auschra, Roland Bal, Marina Böddeker, Ingo Bode, Jeffrey Braithwaite, Clara Breidenbach, Marie Coors, Ibrahim Demirer, Mark Exworthy, Lorenz Harst, Christian Heuser, Julia Hoffmann, Juliane Köberlein-Neu, Karl Krajic, Gregory Maniatopoulos, Russell Mannion, Ralph Möhler, Holger Pfaff, Monika A Rieger, Esther Rind, M A Helge Schnack, M A Anke Wagner, Matthias Weigl, Michel Wensing, Siri Wiig, Eva Wild, Hendrik Wilhelm, Markus Wirtz, Katja Götz

Background: Recent analyses have shown that in health services research in Germany, healthcare organisations are often considered primarily as a study setting, without fully taking their complex organisational nature into account, neither theoretically nor methodologically. Therefore, an initiative was launched to analyse the state of Organisational Health Services Research (OHSR) in Germany and to develop a strategic framework and road map to guide future efforts in the field. This paper summarizes positions that have been jointly developed by consulting experts from the interdisciplinary and international scientific community.

Methods: In July 2023, a scoping workshop over the course of three days was held with 32 (inter)national experts from different research fields centred around OHSR topics using interactive workshop methods. Participants discussed their perspectives on OHSR, analysed current challenges in OHSR in Germany and developed key positions for the field's development.

Results: The seven agreed-upon key positions addressed conceptual and strategic aspects. There was consensus that the field required the development of a research agenda that can guide future efforts. On a conceptual level, the need to address challenges in terms of interdisciplinarity, terminology, organisation(s) as research subjects, international comparative research and utilisation of organisational theory was recognized. On a strategic level, requirements with regard to teaching, promotion of interdisciplinary and international collaboration, suitable funding opportunities and participatory research were identified.

Conclusions: This position paper seeks to serve as a framework to support further development of OHSR in Germany and as a guide for researchers and funding organisations on how to move OHSR forward. Some of the challenges discussed for German OHSR are equally present in other countries. Thus, this position paper can be used to initiate fruitful discussions in other countries.

背景:最近的分析表明,在德国的医疗服务研究中,医疗机构往往被视为主要的研究环境,无论是在理论上还是在方法上,都没有充分考虑到其复杂的组织性质。因此,我们发起了一项倡议,旨在分析德国组织保健服务研究(OHSR)的现状,并制定一个战略框架和路线图,以指导该领域未来的工作。本文总结了跨学科和国际科学界咨询专家共同制定的立场:2023 年 7 月,围绕 OHSR 主题,采用互动研讨会的方法,与来自不同研究领域的 32 位(跨)国家专家举行了为期三天的范围界定研讨会。与会者讨论了他们对职业健康和安全研究的看法,分析了德国职业健康和安全研究目前面临的挑战,并为该领域的发展制定了关键立场:结果:大家一致同意的七个关键立场涉及概念和战略方面。大家一致认为,该领域需要制定一个能够指导未来工作的研究议程。在概念层面上,大家认识到需要应对跨学科、术语、作为研究对象的组织、国际比较研究和组织理论的利用等方面的挑战。在战略层面,确定了教学、促进跨学科和国际合作、适当的资助机会和参与性研究方面的要求:本立场文件旨在作为支持德国进一步发展职业健康与安全研究的框架,并作为研究人员和资助机构如何推进职业健康与安全研究的指南。所讨论的德国职业健康和安全研究面临的一些挑战在其他国家也同样存在。因此,本立场文件可用于在其他国家开展富有成效的讨论。
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引用次数: 0
[Physician Numbers and Employment in Bavaria: Trends in statistics of the Bavarian Medical Association and the Association of Statutory Health Insurance Physicians of Bavaria]. [巴伐利亚的医生人数和就业情况:巴伐利亚医学协会和巴伐利亚法定医疗保险医生协会的统计趋势]。
IF 0.7 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-16 DOI: 10.1055/a-2328-4088
Sophie Gigou, Laura Corazza, Sandra Fett, Martin Tauscher, Roman Gerlach, Ewan Donnachie, Antonius Schneider

Background: Although the number of places at medical schools and physicians in Germany has increased continuously over the past 25 years, there is a threat of a shortage of physicians. Based on data from the Bavarian Medical Association (BLÄK) and the Association of Statutory Health Insurance Physicians of Bavaria (KVB), an analysis of the number of physicians in Bavaria over a longer period of time was carried out in order to understand current developments and possible starting points for the future organization of medical care. The figures were analyzed with regard to the distribution of physicians by outpatient and inpatient sector as well as with regard to the development of the number of employees, the scope of employment and the gender distribution in the outpatient sector.

Methods: Data were taken from the annually published and systematically compiled numbers of physicians from the BLÄK (2000 to 2022) as well as the outpatient billing data of practicing and employed physicians in Bavaria (2010 to 2022), processed by the KVB. Descriptive analyses were performed.

Results: Since 2000, the number of physicians in Bavaria has risen by 83% in the inpatient setting and by 35% in the outpatient setting. As a result, more physicians have been working in hospitals than in outpatient care since 2010. In the outpatient setting the trend is moving away from establishing one's own practice and full-time work towards salaried and part-time employment. Employed physicians have lower average working hours than self-employed physicians. The proportion of women among physicians has steadily increased, with female physicians more likely to be employed and working part-time compared with male physicians. Nevertheless, part-time employment is also prominent among male physicians in some specialties today.

Conclusion: The trend towards practicing in salaried and part-time positions continues unabated and is represented across all specialties, suggesting that more physicians are needed to maintain the number of working hours over time. In addition to incentives and subsidies, this reality must be taken into account when planning care. At the same time, it is questionable whether increasing medical school places without managing them according to need is the right way to address the shortage of physicians in outpatient care when an ever-increasing proportion of physicians is working in inpatient care.

背景:尽管在过去的 25 年中,德国的医学院和医生数量持续增长,但仍存在医生短缺的威胁。根据巴伐利亚州医疗协会(BLÄK)和巴伐利亚州法定医疗保险医生协会(KVB)提供的数据,对巴伐利亚州较长时期内的医生人数进行了分析,以了解当前的发展情况和未来医疗组织的可能起点。分析的数据涉及门诊和住院部门的医生分布情况,以及门诊部门的雇员人数、就业范围和性别分布的发展情况:数据来源于巴伐利亚州卫生局每年公布并系统整理的医生人数(2000 年至 2022 年),以及巴伐利亚州执业和在职医生的门诊账单数据(2010 年至 2022 年)。研究进行了描述性分析:自 2000 年以来,巴伐利亚州的住院医生人数增加了 83%,门诊医生人数增加了 35%。因此,自 2010 年以来,在医院工作的医生人数超过了门诊医生。在门诊领域,趋势是从建立自己的诊所和全职工作转向受薪和兼职工作。受雇医生的平均工作时间低于自雇医生。女性在医生中所占的比例稳步上升,与男性医生相比,女性医生更有可能受雇并从事兼职工作。尽管如此,如今在某些专科中,兼职工作在男医生中也很突出:结论:带薪和兼职执业的趋势有增无减,在所有专科中都有体现,这表明需要更多的医生来长期保持工作时间。在规划医疗服务时,除了激励和补贴措施外,还必须考虑到这一现实情况。与此同时,当越来越多的医生从事住院治疗工作时,增加医学院的学额而不根据需求进行管理,是否是解决门诊医生短缺问题的正确方法,也值得商榷。
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引用次数: 0
Pandemic Preparedness – A proposal for a research infrastructure and its functionalities for a resilient health research system. 大流行病防备 - 关于建立研究基础设施及其功能的建议,以建立具有复原力的卫生研究系统。
IF 0.7 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-15 DOI: 10.1055/a-2365-9179
Simone Scheithauer, Julia Hoffmann, Caroline Lang, Diana Fenz, Milena Maria Berens, Antonia Milena Köster, Ivonne Panchyrz, Lorenz Harst, Kristina Adorjan, Christian Apfelbacher, Sandra Ciesek, Claudia Maria Denkinger, Christian Drosten, Max Geraedts, Ruth Hecker, Wolfgang Hoffmann, André Karch, Thea Koch, Dagmar Krefting, Klaus Lieb, Jörg J Meerpohl, Eva Annette Rehfuess, Nicole Skoetz, Saša Sopka, Thomas von Lengerke, Hauke Wiegand, Jochen Schmitt
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引用次数: 0
Erkenntnisse aus der Durchführung des Masernschutz-Gesetzes nach den ersten drei Jahren seit Einführung – Daten aus Darmstadt Dieburg (Hessen). 麻疹保护法》实施三年后的调查结果--来自达姆施塔特迪堡(黑森)的数据。
IF 0.7 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-12 DOI: 10.1055/a-2365-1400
Katrin Simone Steul, Regina Fertig, Raphaela Heinrich, Roswitha Reisert, Jürgen Krahn
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引用次数: 0
[Key Topics and Activities of Local and District Health Conferences between 2013 and 2022: Results of a Non-Reactive Online Screening]. 2013-2022 年国家立法的市级和区级卫生会议的主题和活动:非反应性在线筛查的结果。
IF 0.7 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-11 DOI: 10.1055/a-2305-7716
Julia Brockschnieder, Julia Haas, Julia Neubauer, Kathrin Prosser, Bertram Szagun

Objectives: The tasks of the Public Health Service include, amongst others, health promotion and disease prevention, health reporting and health planning. In many places, local or district health conferences (HCs) have been established to network and coordinate municipal stakeholders. HCs have been defined in the laws of the German states of Baden-Wurttemberg, Berlin, Hamburg, Hesse, and North Rhine-Westphalia. As systematic and comprehensive studies of HCs are not available, a descriptive analysis of the characteristic features, key topics and activities of HCs in selected states was performed.

Methods: Based on a non-reactive survey of the activities from 2013 to 2022, all HCs in four states (n=110) were covered. Data on structural features, topics and HC activities were gathered in a systematic approach. The topics these conferences dealt with were matched against the health objectives of the states. Following an internal verification of the results, univariate and bivariate analyses were performed for individual states, districts, and the year of establishment.

Results: Overall, topics frequently covered by the HCs are primary care, children's and adolescent health, health at old age, infection prevention and control, physical exercise and diet as well as addiction; in some cases, frequencies of these topics differed heavily among the states and municipalities. The topics covered by the HCs showed a strong association with the health objectives of the respective states. Health care is addressed more often in administrative districts (Landkreise) than in independent cities (kreisfreie Städte). Conferences established more recently (after 2011) exhibited greater activities than older ones in terms of plenary sessions and press releases.

Conclusion: HCs are marked by a wide range of key topics which are based on health objectives of the respective states; however, noticeable differences exist between rural and urban areas. Conferences established more recently show a higher level of activity than older ones, which might point to sustainability issues under the current constraints. Whereas differences between rural and urban areas had already been noted for health-reporting activities, this was not the case for HC activities. The hypotheses derived from this descriptive analysis warrant further examination in order to ensure that the HCs create a sustainable impact.

目标:公共卫生服务机构的任务主要包括促进健康和预防疾病、健康报告和健康规划。许多地方都成立了地方或地区卫生会议 (HCs),以联络和协调市政利益相关者。德国巴登-符腾堡州、柏林州、汉堡州、黑森州和北莱茵-威斯特法伦州的法律都对卫生会议做出了规定。由于目前还没有对市政委员会进行系统全面的研究,因此我们对部分州的市政委员会的特点、主要议题和活动进行了描述性分析:方法:基于对 2013 年至 2022 年期间活动的非反应性调查,涵盖了四个州的所有保健中心(n=110)。通过系统的方法收集了有关结构特征、主题和慧聪网活动的数据。这些会议涉及的主题与各州的卫生目标相匹配。在对结果进行内部核查后,对各个州、地区和成立年份进行了单变量和双变量分析:总体而言,保健中心经常涉及的主题包括初级保健、儿童和青少年健康、老年健康、感染预防和控制、体育锻炼和饮食以及成瘾;在某些情况下,各州和各市涉及这些主题的频率差别很大。保健中心涵盖的主题与各州的保健目标密切相关。行政区(Landkreise)比独立城市(kreisfreie Städte)更经常讨论卫生保健问题。最近(2011 年之后)召开的会议在全体会议和新闻发布方面的活动多于较早召开的会议:根据各州的健康目标,健康大会的主要议题范围广泛,但城乡之间存在明显差异。最近召开的会议比以前召开的会议更活跃,这可能表明在当前的限制条件下存在可持续发展的问题。虽然在健康报告活动方面已经注意到了城乡之间的差异,但在 HC 活动方面情况并非如此。从这一描述性分析中得出的假设值得进一步研究,以确保人道主义协调员产生可持续的影响。
{"title":"[Key Topics and Activities of Local and District Health Conferences between 2013 and 2022: Results of a Non-Reactive Online Screening].","authors":"Julia Brockschnieder, Julia Haas, Julia Neubauer, Kathrin Prosser, Bertram Szagun","doi":"10.1055/a-2305-7716","DOIUrl":"10.1055/a-2305-7716","url":null,"abstract":"<p><strong>Objectives: </strong>The tasks of the Public Health Service include, amongst others, health promotion and disease prevention, health reporting and health planning. In many places, local or district health conferences (HCs) have been established to network and coordinate municipal stakeholders. HCs have been defined in the laws of the German states of Baden-Wurttemberg, Berlin, Hamburg, Hesse, and North Rhine-Westphalia. As systematic and comprehensive studies of HCs are not available, a descriptive analysis of the characteristic features, key topics and activities of HCs in selected states was performed.</p><p><strong>Methods: </strong>Based on a non-reactive survey of the activities from 2013 to 2022, all HCs in four states (n=110) were covered. Data on structural features, topics and HC activities were gathered in a systematic approach. The topics these conferences dealt with were matched against the health objectives of the states. Following an internal verification of the results, univariate and bivariate analyses were performed for individual states, districts, and the year of establishment.</p><p><strong>Results: </strong>Overall, topics frequently covered by the HCs are primary care, children's and adolescent health, health at old age, infection prevention and control, physical exercise and diet as well as addiction; in some cases, frequencies of these topics differed heavily among the states and municipalities. The topics covered by the HCs showed a strong association with the health objectives of the respective states. Health care is addressed more often in administrative districts (Landkreise) than in independent cities (kreisfreie Städte). Conferences established more recently (after 2011) exhibited greater activities than older ones in terms of plenary sessions and press releases.</p><p><strong>Conclusion: </strong>HCs are marked by a wide range of key topics which are based on health objectives of the respective states; however, noticeable differences exist between rural and urban areas. Conferences established more recently show a higher level of activity than older ones, which might point to sustainability issues under the current constraints. Whereas differences between rural and urban areas had already been noted for health-reporting activities, this was not the case for HC activities. The hypotheses derived from this descriptive analysis warrant further examination in order to ensure that the HCs create a sustainable impact.</p>","PeriodicalId":47653,"journal":{"name":"Gesundheitswesen","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140853115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Five Key Questions for Health Services Research: are SHI Claims Data Suitable for Your Research Project?] 【卫生服务研究的五个关键问题:SHI索赔数据是否适合您的研究项目?】
IF 0.7 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 Epub Date: 2023-10-20 DOI: 10.1055/a-2098-3039
Peter Ihle, Udo Schneider, Verena Vogt

Health services research examines the structures and processes of health care under everyday conditions. Routine data of the statutory health insurance (SHI) - the so-called routine practice data - represent real health care and are therefore an important data source for health services research. This paper presents 5 key questions that researchers and data-holding institutions can use to assess the suitability of this data source for answering their health services research question. The aim of these guiding questions is to generate a common understanding between researchers and data-holding institutions of the research project, the research objective, and the feasibility of implementation in health services research. The five guiding questions cover the formulation of the research question, the planned method, the target population, the relevant study periods, and the required information from SHI data. These methodologically oriented guiding questions are supplemented by the question of how the results of the research project could improve care. Thus, for researchers, the five guiding questions provide an initial structuring for data requests; for data-holding institutions, they provide a framework for considering possible involvement in or support of a research idea in health services research.

卫生服务研究考察了日常条件下的卫生保健结构和过程。法定健康保险(SHI)的常规数据——即所谓的常规实践数据——代表了真实的医疗保健,因此是医疗服务研究的重要数据来源。本文提出了5个关键问题,研究人员和数据持有机构可以用来评估该数据源是否适合回答他们的卫生服务研究问题。这些指导性问题的目的是在研究人员和数据持有机构之间就研究项目、研究目标以及在卫生服务研究中实施的可行性达成共识。五个指导性问题包括研究问题的制定、计划方法、目标人群、相关研究周期以及SHI数据所需的信息。这些以方法论为导向的指导问题辅以研究项目的结果如何改善护理的问题。因此,对于研究人员来说,五个指导性问题为数据请求提供了初步结构;对于数据持有机构来说,它们提供了一个框架,用于考虑是否可能参与或支持卫生服务研究的研究理念。
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引用次数: 0
AGENS Methodenworkshop und Career Day 2023 – face2face in Köln. AGENS 方法研讨会和 2023 年职业日 - 在科隆面对面。
IF 0.7 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 Epub Date: 2024-07-29 DOI: 10.1055/a-2312-4993
Ingo Meyer
{"title":"AGENS Methodenworkshop und Career Day 2023 – face2face in Köln.","authors":"Ingo Meyer","doi":"10.1055/a-2312-4993","DOIUrl":"10.1055/a-2312-4993","url":null,"abstract":"","PeriodicalId":47653,"journal":{"name":"Gesundheitswesen","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Development and Internal Validation of Case Definitions for Prevalence Estimation of Microvascular Complications of Diabetes in Routine Data]. [常规数据中用于估算糖尿病微血管并发症患病率的病例定义的开发和内部验证]。
IF 0.7 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 Epub Date: 2023-05-30 DOI: 10.1055/a-2061-6954
Lukas Reitzle, Ingrid Köster, Oktay Tuncer, Christian Schmidt, Ingo Meyer

Background: Surveillance of diabetes requires up-to-date information on the prevalence of diabetes and its complications over time. For this purpose, statutory health insurance (SHI) data is being increasingly used, as the data is available in a timely fashion and case numbers enable detailed estimates also of diabetes complications. The aim of the present study was the development and internal validation of case definitions for the prevalence estimation of diabetic retinopathy (DRP), diabetic polyneuropathy (DPN) and diabetic foot syndrome (DFS).

Methods: Persons with diabetes differentiated by type 1, type 2, and other diabetes in an age- and sex-stratified sample of persons insured by Barmer SHI in 2018 (n=72,744) comprised the study popuation. Based on the central ICD codes for microvascular complications (DRP: H36.0; DPN: G63.2; DFS: E1X.74/.75), case definitions were developed including additional ICD codes for complications without direct diabetes reference. Subsequently, the case definitions were internally validated. For the validation, coding in the inpatient setting (m1S) or repeatedly in the outpatient setting (m2Q) as well as coding of specific procedures (EBM, OPS) and drug prescriptions or by relevant specialists were considered. Additionally, we analysed the documentation of the diagnoses in the previous years.

Results: In 2018, the prevalence of the central ICD codes was 8.4% for DRP (H36.0), 18.9% for DPN (G63.2) and 13.4% for DFS (E1X.74/.75). After inclusion of additional ICD codes in the case definition, prevalence increased significantly for DRP (9.6%) and DPN (20.7%), and barely for DFS (13.5%). Internal validation confirmed the majority of diagnoses (DRP: 96.7%; DPN: 96.5% DFS: 95.8%) and m2Q represented the most relevant criterion. When up to four previous years were considered, prevalences were up to 30% higher for DPN and DFS and up to 64% higher for DRP.

Conclusion: The inclusion of additional ICD codes in the case definition of microvascular complications of diabetes appears meaningful, as this increases the sensitivity of the prevalence estimate. Internal validation suggests that the documented diagnoses are plausible. However, not all diagnoses are documented annually, leading to an underestimation of the prevalence using a cross-sectional study design of one year.

背景:对糖尿病的监测需要有关糖尿病发病率及其并发症的最新信息。为此,法定医疗保险(SHI)数据正被越来越多地使用,因为这些数据可以及时获得,而且病例数还可以对糖尿病并发症进行详细估算。本研究的目的是为估算糖尿病视网膜病变(DRP)、糖尿病多发性神经病变(DPN)和糖尿病足综合征(DFS)的患病率制定病例定义并进行内部验证:研究对象包括2018年巴尔默市社会保险局投保人(n=72744)中按年龄和性别分层抽样的1型、2型和其他糖尿病患者。根据微血管并发症的中央 ICD 编码(DRP:H36.0;DPN:G63.2;DFS:E1X.74/.75),制定了病例定义,包括无直接糖尿病参照的并发症的附加 ICD 编码。随后,对病例定义进行了内部验证。在验证过程中,我们考虑了住院病人的编码(m1S)或门诊病人的重复编码(m2Q),以及特定程序(EBM、OPS)和药物处方或相关专家的编码。此外,我们还分析了前几年的诊断记录:2018 年,DRP(H36.0)、DPN(G63.2)和 DFS(E1X.74/.75)的中心 ICD 代码流行率分别为 8.4%、18.9% 和 13.4%。在病例定义中加入额外的 ICD 代码后,DRP(9.6%)和 DPN(20.7%)的患病率显著增加,而 DFS(13.5%)的患病率几乎没有增加。内部验证确认了大多数诊断(DRP:96.7%;DPN:96.5%;DFS:95.8%),m2Q 是最相关的标准。如果考虑多达四年前的情况,DPN和DFS的患病率最多可增加30%,DRP的患病率最多可增加64%:结论:在糖尿病微血管并发症的病例定义中加入额外的 ICD 代码似乎很有意义,因为这提高了患病率估计的敏感性。内部验证表明,记录的诊断是可信的。然而,并非所有的诊断都是每年记录一次,这导致使用一年的横断面研究设计低估了患病率。
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引用次数: 0
[Schätzung der Wirksamkeit der Grippeimpfung anhand von Sekundärdaten: Eine Kohortenstudie und Propensity-Score-Matching-Analyse von Leistungsdaten aus Baden-Württemberg]. [利用二手数据估算流感疫苗接种效果:对巴登-符腾堡州的绩效数据进行队列研究和倾向得分匹配分析]。
IF 0.7 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 Epub Date: 2023-12-22 DOI: 10.1055/a-2173-8160
Felix Wicke, Eva Lorenz, Roman Michael Pokora

Ziel war es die Wirksamkeit der Influenza-Impfung (VE) für die Grippesaison 2014/2015 auf Grundlage von Routinedaten aus Krankenkassendatensatz zu schätzen und zu replizieren. Zusätzlich sollten methodische Aspekte untersucht werden. Es wurden Abrechnungsdaten von 2,64 Millionen Versicherten der AOK Baden-Württemberg mit dortigem Wohnsitz ab 15 Jahren analysiert. Basierend auf Abrechnungsdaten für die Influenza-Impfung 2014, wurden die Teilnehmer als ungeimpft oder geimpft klassifiziert. Kovariablen, die den Zusammenhang zwischen Impfung und Influenzainfektion beeinträchtigen könnten, wurden berücksichtigt. Hierzu gehörten Alter, Geschlecht, Wohnort sowie Kovariablen, die auf den Gesundheitszustand und die Inanspruchnahme von Gesundheitsdienstleistungen hinweisen. Der primäre Endpunkt war ein Krankenhausaufenthalt wegen Influenza während der Grippesaison 2015. Zu den sekundären Endpunkten gehörten unter anderem Krankenhausaufenthalte wegen Lungenentzündung und die Gesamtmortalität. Um eine vergleichbare Gruppe von geimpften und ungeimpften Teilnehmern zu ermitteln, wurde ein Propensity-Score-Matching (PSM) durchgeführt. Es wurde eine Bias-Analyse durchgeführt, bei der die VE vor und nach der Grippesaison geschätzt wurde, also zu Zeitpunkten, in denen angenommen wurde, dass die Influenza nicht in der Bevölkerung zirkulierte und die Impfung nicht wirken konnte. Insgesamt konnten 839.706 Teilnehmer 1:1 gematcht werden. Die geschätzte VE (basierend auf Influenza bedingten Krankenhausaufenthalten) betrug 27% [95%Konfidenzintervall (KI): 17%; 36%], was der Schätzung des RKI für dieselbe Saison (27% [95%KI: -1%; 47%]) entspricht. Die Bias-Analyse zeigte, dass das Ergebnis teilweise durch residuale Konfundierung erklärt werden kann, was zu einer potenziellen Überschätzung des zugrunde liegenden Effekts führt. Die Ergebnisse der sekundären Endpunkte zeigten ähnliche Ergebnisse, obwohl sie wahrscheinlich in höherem Maße durch residuale Konfundierung bedingt sind. Zusammenfassend zeigt sich, dass (1) sekundäre Daten der deutschen Krankenkassen verwendet werden können, um plausible VE-Schätzungen abzuleiten, und dass (2) das PSM eine nützliche und transparente Methode zur Ableitung dieser Schätzungen ist. Darüber hinaus ist (3) residuale Konfundierung ein relevantes Problem in Beobachtungsstudien zu VE und (4) Bias-Analysen vor- und nach der Grippesaison sind eine wesentliche Ergänzung für die Interpretation der Ergebnisse.

目的是根据医疗保险数据集的常规数据,估算并复制 2014/2015 年流感季节的流感疫苗接种(VE)效果。此外,还将对方法论方面进行分析。我们分析了巴登一符腾堡州医疗保险协会(AOK Baden-Württemberg)的 264 万 15 岁以上投保人的账单数据。根据 2014 年流感疫苗接种的账单数据,参保者被分为未接种和已接种两类。分析中考虑了可能影响疫苗接种与流感感染之间关系的变量。这些因素包括年龄、性别、居住地以及表明健康状况和医疗保健使用情况的协变量。主要终点是在2015年流感季节因流感住院,次要终点包括肺炎住院和全因死亡率。为确定接种疫苗和未接种疫苗参与者的可比群体,进行了倾向得分匹配(PSM)。在流感季节之前和之后,即假定流感没有在人群中流行、疫苗接种无法发挥作用的时候,进行了偏差分析,以估计VE。共有 839 706 名参与者可进行 1:1 配对。估计的 VE(基于与流感相关的住院病例)为 27% [95% 置信区间 (CI):17%; 36%],与同一季度的 RKI 估计值(27% [95% CI:-1%; 47%])一致。偏倚分析表明,残余混杂因素可以部分解释这一结果,从而导致潜在效应可能被高估。次要结果也显示了类似的结果,尽管这些结果可能在更大程度上是由残余混杂因素造成的。总之,(1) 德国医疗保险基金的二级数据可用于得出可信的 VE 估计值,(2) PSM 是得出这些估计值的一种有用而透明的方法。此外,(3) 剩余混杂是 VE 观察性研究中的一个相关问题,(4) 流感季节前后的偏差分析是解释结果的一个重要补充。
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