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Stakeholder Perspectives on Humanistic Implementation of Computer Perception in Health Care: Qualitative Study. 利益相关者视角下医疗保健中计算机感知的人本化实施:质性研究。
IF 5.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2026-01-05 DOI: 10.2196/79182
Kristin M Kostick-Quenet, Meghan E Hurley, Syed Ayaz, John D Herrington, Casey J Zampella, Julia Parish-Morris, Birkan Tunç, Gabriel Lázaro-Muñoz, Jennifer Blumenthal-Barby, Eric A Storch
<p><strong>Background: </strong>Computer perception (CP) technologies-including digital phenotyping, affective computing, and related passive sensing approaches-offer unprecedented opportunities to personalize health care, especially mental health care, yet they also provoke concerns about privacy, bias, and the erosion of empathic, relationship-centered practice. At present, it remains elusive what stakeholders who design, deploy, and experience these tools in real-world settings perceive as the risks and benefits of CP technologies.</p><p><strong>Objective: </strong>This study aims to explore key stakeholder perspectives on the potential benefits, risks, and concerns associated with integrating CP technologies into patient care. A better understanding of these concerns is crucial for responding to and mitigating such concerns via design implementation strategies that augment, rather than compromise, patient-centered and humanistic care and associated outcomes.</p><p><strong>Methods: </strong>We conducted in-depth, semistructured interviews with 102 stakeholders involved at key points in CP's development and implementation: adolescent patients (n=20) and their caregivers (n=20); frontline clinicians (n=20); technology developers (n=21); and ethics, legal, policy, or philosophy scholars (n=21). Interviews (~ 45 minutes each) explored perceived benefits, risks, and implementation challenges of CP in clinical care. Transcripts underwent thematic analysis by a multidisciplinary team; reliability was enhanced through double coding and consensus adjudication.</p><p><strong>Results: </strong>Stakeholders raised concerns across 7 themes: (1) Data Privacy and Protection (88/102, 86.3%); (2) Trustworthiness and Integrity of CP Technologies (72/102, 70.6%); (3) direct and indirect Patient Harms (65/102, 63.7%); (4) Utility and Implementation Challenges (60/102, 58.8%); (5) Patient-Specific Relevance (24/102, 23.5%); (6) Regulation and Governance (17/102, 16.7%); and (7) Philosophical Critiques of reductionism (13/102, 12.7%). A cross-cutting insight was the primacy of context and subjective meaning in determining whether CP outputs are clinically valid and actionable. Participants warned that without attention to these factors, algorithms risk misclassification and dehumanization of care.</p><p><strong>Conclusions: </strong>To operationalize humanistic safeguards, we propose "personalized road maps": co-designed plans that predetermine which metrics will be monitored, how and when feedback is shared, thresholds for clinical action, and procedures for reconciling discrepancies between algorithmic inferences and lived experience. Road maps embed patient education, dynamic consent, and tailored feedback, thereby aligning CP deployment with patient autonomy, therapeutic alliance, and ethical transparency. This multistakeholder study provides the first comprehensive, evidence-based account of relational, technical, and governance challenges raised by CP tools i
背景:计算机感知(CP)技术——包括数字表型、情感计算和相关的被动感知方法——为个性化医疗保健,特别是精神卫生保健提供了前所未有的机会,但它们也引发了对隐私、偏见和共情、以关系为中心的实践侵蚀的担忧。目前,在现实环境中设计、部署和体验这些工具的利益相关者认为CP技术的风险和好处仍然是难以捉摸的。目的:本研究旨在探讨关键利益相关者对将CP技术整合到患者护理中的潜在利益、风险和关注点的看法。更好地了解这些问题对于通过设计实施策略来应对和减轻这些问题至关重要,这些策略可以增强而不是妥协以患者为中心的人文关怀和相关结果。方法:我们对102名参与CP发展和实施关键点的利益相关者进行了深入的半结构化访谈:青少年患者(n=20)和他们的照顾者(n=20);一线临床医生(n=20);技术开发人员(n=21);以及伦理、法律、政策或哲学学者(n=21)。访谈(每次约45分钟)探讨了CP在临床护理中的获益、风险和实施挑战。一个多学科小组对笔录进行了专题分析;通过双重编码和共识裁决,提高了可靠性。结果:利益相关者提出了7个主题的担忧:(1)数据隐私和保护(88/102,86.3%);(2) CP Technologies的诚信与诚信(72/102,70.6%);(3)患者直接和间接危害(65/102,63.7%);(4)效用和实施挑战(60/102,58.8%);(5)患者特异性相关性(24/102,23.5%);(6)监管和治理(17/102,16.7%);(7)对还原论的哲学批判(13/102,12.7%)。在确定CP输出是否临床有效和可操作时,跨领域的洞察力是上下文和主观意义的首要因素。与会者警告说,如果不注意这些因素,算法可能会错误分类和使护理失去人性化。结论:为了实施人性化的保障措施,我们提出了“个性化路线图”:共同设计的计划,预先确定将监测哪些指标,如何以及何时共享反馈,临床行动的阈值,以及调和算法推断与生活经验之间差异的程序。路线图嵌入了患者教育、动态同意和量身定制的反馈,从而使CP部署与患者自主权、治疗联盟和伦理透明度保持一致。这项多利益相关者研究首次提供了全面的、基于证据的关于临床护理中CP工具所带来的关系、技术和治理挑战的描述。通过将这些见解转化为个性化的路线图,我们为开发人员、临床医生和政策制定者提供了一个实用的框架,以寻求利用持续的行为数据,同时保留护理的人文核心。
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引用次数: 0
Physician Perspectives on the Impact of Artificial Intelligence on the Therapeutic Relationship in Mental Health Care: Qualitative Study. 医师对人工智能对心理健康护理治疗关系影响的看法:质性研究
IF 5.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-30 DOI: 10.2196/81970
Isabel B Weir, Austin M Stroud, Jeremiah J Stout, Barbara A Barry, Arjun P Athreya, William V Bobo, Richard R Sharp

Background: The therapeutic relationship is a professional partnership between clinicians and patients that supports open communication and clinical decision-making. This relationship is critical to the delivery of effective mental health care. The integration of artificial intelligence (AI) into mental health care has the potential to support accessibility and personalized care; however, little is known about how AI might affect the dynamics of the therapeutic relationship.

Objective: This study aimed to ascertain how physicians anticipate AI tools will impact the therapeutic relationship in mental health care.

Methods: We conducted 42 in-depth interviews with psychiatrists and family medicine practitioners to investigate physician perceptions regarding the impact of AI on mental health care.

Results: Physicians identified several disruptions from AI use, noting that these tools could impact the dyad of the patient-physician relationship in ways that are both positive and negative. The main themes that emerged included potential disruptions to the therapeutic relationship, shifts in shared decision-making dynamics, and the importance of transparent AI use. Participants suggested that AI tools could create efficiencies that allow for relationship building as well as help avoid issues with miscommunication during psychotherapeutic interactions. However, they also expressed concerns that AI tools might not adequately capture aspects of the therapeutic relationship, such as empathy, that are vital to mental health care. Physicians also raised issues related to the impact that AI tools will have on maintaining relationships with patients.

Conclusions: As AI applications become increasingly integrated into mental health care, it is crucial to assess how this integration may support or disrupt the therapeutic relationship. Physician acceptance of emerging AI tools may be highly dependent on how well the human elements of mental health care are preserved.

背景:治疗关系是临床医生和患者之间的专业伙伴关系,支持开放的沟通和临床决策。这种关系对于提供有效的精神卫生保健至关重要。将人工智能(AI)整合到精神卫生保健中有可能支持可及性和个性化护理;然而,人们对人工智能如何影响治疗关系的动态知之甚少。目的:本研究旨在确定医生如何预测人工智能工具将影响心理卫生保健中的治疗关系。方法:我们对精神病学家和家庭医学从业者进行了42次深度访谈,以调查医生对人工智能对精神卫生保健影响的看法。结果:医生们发现了人工智能使用带来的一些干扰,并指出这些工具可能会以积极和消极的方式影响医患关系。出现的主要主题包括对治疗关系的潜在破坏,共同决策动态的转变,以及透明使用人工智能的重要性。参与者建议,人工智能工具可以创造效率,允许建立关系,并有助于避免心理治疗互动过程中的误解问题。然而,他们也担心,人工智能工具可能无法充分捕捉到治疗关系的各个方面,比如同理心,而这对精神卫生保健至关重要。医生们还提出了与人工智能工具对维持与患者关系的影响相关的问题。结论:随着人工智能应用越来越多地融入精神卫生保健,评估这种整合如何支持或破坏治疗关系至关重要。医生对新兴人工智能工具的接受程度可能高度取决于精神卫生保健中人类因素的保留程度。
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引用次数: 0
The Stanford Brainstorm Social Media Safety Plan (SMS): Introducing a New Tool. 斯坦福头脑风暴社交媒体安全计划(SMS):引入新工具。
IF 5.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-29 DOI: 10.2196/72057
Darja Djordjevic, Nina Vasan

Unlabelled: We propose the Stanford Brainstorm Social Media Safety Plan (SMS) as a user-friendly, collaborative, and effective tool to mitigate the imminent dangers and risks to mental health that are associated with social media use by children, adolescents, and young adults. This tool is informed and inspired by suicide safety plans as part of suicide safety planning, which have long shaped the standard of care for psychiatric discharges from inpatient units, emergency rooms, and comprehensive psychiatric emergency programs, as well as longitudinal outpatient care following occurrences of suicidal ideation or suicide attempts. In many systems including those of the Veterans Health Administration, they constitute an absolute requirement prior to the discharge of the patient. This social media safety plan is to be used proactively, in times of normalcy as well as crisis. While there are parental controls for digital devices and online platforms, official legal age requirements for online accounts, and individual parenting approaches, there is a dearth of practical tools that youth, families, schools, and communities can use to shape and alter social media use parameters, rules, and habits. Furthermore, providers in psychiatry, child and adolescent psychiatry, and mental health at large are often confronted with behaviors and issues related to social media use during time- and resource-limited appointments, providing a massive opportunity for interventions that are harm reduction-oriented and easy to disseminate. While it has not been studied in a clinical trial, we have used it extensively with patients and families, and presented it to larger audiences at mental health and technology conferences over the past two years. The responses and feedback we have received, as well as reported anecdotal experiences with using it, have been overwhelmingly positive. An already unfolding child and adolescent mental health epidemic in the United States has been observed and deepened partly by way of easy access to social media (and digital-screen time) with inadequate safeguards and monitoring in place. Social media's impacts and related interventions require a multitiered biopsychosocial and cultural approach: at the level of the individual child, the family, the school, the state, the market, and the nation. At the level of youth and their parents or caregivers, practical tools are desperately needed. We propose the SMS as one such significant tool.

未标记:我们提出斯坦福头脑风暴社交媒体安全计划(SMS)作为一种用户友好,协作和有效的工具,以减轻与儿童,青少年和年轻人使用社交媒体相关的迫在眉睫的心理健康危险和风险。作为自杀安全计划的一部分,自杀安全计划长期以来塑造了住院病房、急诊室和综合精神科急诊项目的精神科出院护理标准,以及自杀意念或自杀企图发生后的纵向门诊护理,这一工具受到自杀安全计划的启发和启发。在包括退伍军人健康管理局在内的许多系统中,它们构成了病人出院前的绝对要求。这一社交媒体安全计划将在正常情况下和危机情况下积极使用。虽然有家长对数字设备和在线平台的控制,对在线账户的官方法定年龄要求,以及个人育儿方法,但年轻人、家庭、学校和社区可以用来塑造和改变社交媒体使用参数、规则和习惯的实用工具却很缺乏。此外,精神病学、儿童和青少年精神病学以及整个精神卫生的提供者在时间和资源有限的预约期间经常面临与社交媒体使用有关的行为和问题,这为减少伤害和易于传播的干预措施提供了巨大的机会。虽然它还没有在临床试验中进行研究,但我们已经在患者和家属中广泛使用了它,并在过去两年中在心理健康和技术会议上向更多的观众展示了它。我们收到的回应和反馈,以及使用它的传闻经验,都是非常积极的。在美国,儿童和青少年心理健康流行病已经开始蔓延,部分原因是社交媒体(和数字屏幕时间)的容易访问,而保障措施和监测措施不足。社交媒体的影响和相关干预需要多层次的生物、心理、社会和文化方法:在孩子个人、家庭、学校、国家、市场和国家的层面上。在青年及其父母或照顾者层面,迫切需要实用工具。我们建议短信作为这样一个重要的工具。
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引用次数: 0
ChatGPT Clinical Use in Mental Health Care: Scoping Review of Empirical Evidence. ChatGPT在精神卫生保健中的临床应用:经验证据的范围审查。
IF 5.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-24 DOI: 10.2196/81204
Raluca Balan, Thomas P Gumpel

Background: As mental health challenges continue to rise globally, there is an increasing interest in the use of GPT models, such as ChatGPT, in mental health care. A few months after its release, tens of thousands of users interacted with GPT-based therapy bots, with mental health support identified as the primary use case. ChatGPT offers scalable and immediate support through natural language processing capabilities, but their clinical applicability, safety, and effectiveness remain underexplored.

Objective: This scoping review aims to provide a comprehensive overview of the main clinical applications of ChatGPT in mental health care, along with the existing empirical evidence for its performance.

Methods: A systematic search was conducted in 8 electronic databases in April 2025 to identify primary studies. Eligible studies included primary research, reporting on the evaluation of a ChatGPT clinical application implemented for a mental health care-specific purpose.

Results: In total, 60 studies were included in this scoping review. The results highlighted that most applications used generic ChatGPT and focused on the detection of mental health problems and counseling and treatment. At the same time, only a minority of studies investigated ChatGPT use in clinical decision facilitation and prognosis tasks. Most of the studies were prompt experiments, in which standardized text inputs-designed to mimic clinical scenarios, patient descriptions, or practitioner queries-are submitted to ChatGPT to evaluate its performance in mental health-related tasks. In terms of performance, ChatGPT shows good accuracy in binary diagnostic classification and differential diagnosis, simulating therapeutic conversation, providing psychoeducation, and conducting specific therapeutic strategies. However, ChatGPT has significant limitations, particularly with more complex clinical presentations and its overly pessimistic prognostic outputs. Nevertheless, overall, when compared to mental health experts or other artificial intelligence models, ChatGPT approximates or surpasses their performance in conducting various clinical tasks. Finally, custom ChatGPT use was associated with better performance, especially in counseling and treatment tasks.

Conclusions: While ChatGPT offers promising capabilities for mental health screening, psychoeducation, and structured therapeutic interactions, its current limitations highlight the need for caution in clinical adoption. These limitations also underscore the need for rigorous evaluation frameworks, model refinement, and safety protocols before broader clinical integration. Moreover, the variability in performance across versions, tasks, and diagnostic categories also invites a more nuanced reflection on the conditions under which ChatGPT can be safely and effectively integrated into mental health settings.

背景:随着全球精神卫生挑战的不断增加,人们对在精神卫生保健中使用GPT模型(如ChatGPT)的兴趣越来越大。在发布几个月后,成千上万的用户与基于gpt的治疗机器人进行了互动,心理健康支持被确定为主要用例。ChatGPT通过自然语言处理能力提供可扩展和即时的支持,但其临床适用性、安全性和有效性仍有待进一步研究。目的:本综述旨在全面概述ChatGPT在精神卫生保健中的主要临床应用,以及其性能的现有经验证据。方法:于2025年4月对8个电子数据库进行系统检索,确定初步研究。符合条件的研究包括初步研究,报告了对ChatGPT临床应用的评估,用于特定的精神卫生保健目的。结果:本综述共纳入60项研究。结果强调,大多数应用程序使用通用ChatGPT,并侧重于心理健康问题的检测和咨询和治疗。同时,只有少数研究调查了ChatGPT在临床决策促进和预后任务中的应用。大多数研究都是提示实验,其中标准化的文本输入——旨在模仿临床场景、患者描述或医生询问——被提交给ChatGPT,以评估其在心理健康相关任务中的表现。在性能方面,ChatGPT在二元诊断分类和鉴别诊断、模拟治疗对话、提供心理教育、制定具体治疗策略等方面表现出较好的准确性。然而,ChatGPT有明显的局限性,特别是在更复杂的临床表现和过于悲观的预后输出方面。然而,总的来说,与心理健康专家或其他人工智能模型相比,ChatGPT在执行各种临床任务方面的表现接近或超过了他们。最后,自定义ChatGPT的使用与更好的表现有关,特别是在咨询和治疗任务中。结论:虽然ChatGPT在心理健康筛查、心理教育和结构化治疗互动方面提供了很有前景的能力,但其目前的局限性突出了在临床应用时需要谨慎。这些限制也强调了在更广泛的临床整合之前需要严格的评估框架、模型改进和安全协议。此外,不同版本、任务和诊断类别的表现差异也引起了对ChatGPT可以安全有效地集成到心理健康环境中的条件的更细致的反思。
{"title":"ChatGPT Clinical Use in Mental Health Care: Scoping Review of Empirical Evidence.","authors":"Raluca Balan, Thomas P Gumpel","doi":"10.2196/81204","DOIUrl":"10.2196/81204","url":null,"abstract":"<p><strong>Background: </strong>As mental health challenges continue to rise globally, there is an increasing interest in the use of GPT models, such as ChatGPT, in mental health care. A few months after its release, tens of thousands of users interacted with GPT-based therapy bots, with mental health support identified as the primary use case. ChatGPT offers scalable and immediate support through natural language processing capabilities, but their clinical applicability, safety, and effectiveness remain underexplored.</p><p><strong>Objective: </strong>This scoping review aims to provide a comprehensive overview of the main clinical applications of ChatGPT in mental health care, along with the existing empirical evidence for its performance.</p><p><strong>Methods: </strong>A systematic search was conducted in 8 electronic databases in April 2025 to identify primary studies. Eligible studies included primary research, reporting on the evaluation of a ChatGPT clinical application implemented for a mental health care-specific purpose.</p><p><strong>Results: </strong>In total, 60 studies were included in this scoping review. The results highlighted that most applications used generic ChatGPT and focused on the detection of mental health problems and counseling and treatment. At the same time, only a minority of studies investigated ChatGPT use in clinical decision facilitation and prognosis tasks. Most of the studies were prompt experiments, in which standardized text inputs-designed to mimic clinical scenarios, patient descriptions, or practitioner queries-are submitted to ChatGPT to evaluate its performance in mental health-related tasks. In terms of performance, ChatGPT shows good accuracy in binary diagnostic classification and differential diagnosis, simulating therapeutic conversation, providing psychoeducation, and conducting specific therapeutic strategies. However, ChatGPT has significant limitations, particularly with more complex clinical presentations and its overly pessimistic prognostic outputs. Nevertheless, overall, when compared to mental health experts or other artificial intelligence models, ChatGPT approximates or surpasses their performance in conducting various clinical tasks. Finally, custom ChatGPT use was associated with better performance, especially in counseling and treatment tasks.</p><p><strong>Conclusions: </strong>While ChatGPT offers promising capabilities for mental health screening, psychoeducation, and structured therapeutic interactions, its current limitations highlight the need for caution in clinical adoption. These limitations also underscore the need for rigorous evaluation frameworks, model refinement, and safety protocols before broader clinical integration. Moreover, the variability in performance across versions, tasks, and diagnostic categories also invites a more nuanced reflection on the conditions under which ChatGPT can be safely and effectively integrated into mental health settings.</p>","PeriodicalId":48616,"journal":{"name":"Jmir Mental Health","volume":"12 ","pages":"e81204"},"PeriodicalIF":5.8,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12735656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145829022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Paradigm Shift in Progress: Generative AI's Evolving Role in Mental Health Care. 正在进行的范式转变:生成人工智能在精神卫生保健中的演变作用。
IF 5.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-17 DOI: 10.2196/82369
John Torous, Andrea Cipriani

Unlabelled: Generative artificial intelligence (AI) is reshaping mental health but the direction of that change remains unclear. In this commentary, we examine the recent evidence and trends in mental health AI to identify where AI can provide value for the field while avoiding the pitfalls that have challenged the smartphone app and VR space. While AI technology will continue to improve, those advances alone are not enough to move AI from mental wellness to psychiatric tools and a new generation of clinical investigation, integration, and leadership will unlock the full value of AI.

未标注:生成式人工智能(AI)正在重塑心理健康,但这种变化的方向尚不清楚。在这篇评论中,我们研究了心理健康人工智能的最新证据和趋势,以确定人工智能可以为该领域提供价值的地方,同时避免智能手机应用程序和虚拟现实领域面临的陷阱。虽然人工智能技术将继续改进,但仅凭这些进步不足以将人工智能从心理健康转移到精神病学工具,新一代的临床研究、整合和领导力将释放人工智能的全部价值。
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引用次数: 0
Effectiveness and User Experience of Immersive Virtual Reality in Cognitive Rehabilitation for Attention-Deficit/Hyperactivity Disorder: Systematic Review. 沉浸式虚拟现实在注意力缺陷/多动障碍认知康复中的有效性和用户体验:系统综述。
IF 5.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-12 DOI: 10.2196/71963
Natalie Single, Winona Mishelle Graham, Joshua Kelson, Danielle Sulikowski

Background: Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by difficulties in attention, impulsivity, and hyperactivity. These difficulties can result in pervasive and longstanding psychological distress and social, academic, and occupational impairments.

Objective: This systematic review aims to investigate the effectiveness and user experience (ie, safety, usability, acceptability, and attrition) outcomes of immersive virtual reality (VR) interventions for cognitive rehabilitation in people with ADHD and identify research gaps and avenues for future research in this domain.

Methods: Peer-reviewed journal articles that appraised the treatment impact of any immersive VR-based intervention on cognitive abilities in people of all ages with ADHD were eligible for inclusion. The following databases were searched up until November 2024: Cochrane Library, IEEE Explore Digital Library, PsycINFO, PubMed, Scopus, and Web of Science. Records were screened on title and abstract information after deduplication, leading to full-text appraisal of the remaining records. Findings from eligible articles were extracted into a standardized coding sheet before being tabulated and reported with a narrative synthesis.

Results: Out of 1046 records identified, 15 articles met the inclusion criteria. Immersive VR-based interventions for people with ADHD were generally effective in improving cognitive abilities, such as attention, memory, and executive functioning. User experience outcomes were also generally positive, with low levels of simulator sickness and minimal attrition reported during VR-based treatment.

Conclusions: Immersive VR-based interventions hold promise for effectively, safely, and rapidly treating cognitive deficits in children and adults with ADHD. However, more studies are required to examine their longitudinal impact beyond treatment cessation.

背景:注意缺陷/多动障碍(ADHD)是一种以注意力困难、冲动和多动为特征的神经发育障碍。这些困难可能导致普遍和长期的心理困扰以及社会、学业和职业障碍。目的:本系统综述旨在探讨沉浸式虚拟现实(VR)干预对ADHD患者认知康复的有效性和用户体验(即安全性、可用性、可接受性和损耗)结果,并确定该领域未来研究的研究空白和途径。方法:同行评议的期刊文章,评估任何沉浸式基于vr的干预对所有年龄ADHD患者认知能力的治疗影响,符合纳入条件。以下数据库被检索到2024年11月:Cochrane Library, IEEE Explore Digital Library, PsycINFO, PubMed, Scopus和Web of Science。在重复数据删除后,对记录的标题和摘要信息进行筛选,从而对剩余记录进行全文评估。符合条件的文章的调查结果被提取到一个标准化的编码表,然后制成表格,并以叙述综合报告。结果:1046篇文献中有15篇符合纳入标准。针对ADHD患者的沉浸式vr干预通常在提高认知能力(如注意力、记忆力和执行功能)方面有效。用户体验结果也总体上是积极的,在基于vr的治疗期间,报告的模拟器病和磨损程度很低。结论:沉浸式vr干预有望有效、安全、快速地治疗儿童和成人ADHD患者的认知缺陷。然而,需要更多的研究来检验它们在停止治疗后的纵向影响。
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引用次数: 0
Smartwatch-Derived Digital Phenotypes Relate to Psychopathology Dimensions in Patients With Psychotic Spectrum Disorders: Longitudinal Observational Study. 智能手表衍生的数字表型与精神病谱系障碍患者的精神病理维度相关:纵向观察研究
IF 5.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-12 DOI: 10.2196/75774
Vasiliki Garyfalli, Emmanouil Kalisperakis, Alexandros Smyrnis, Marina Lazaridi, Thomas Karantinos, Asimakis Mantas, Panagiotis P Filntisis, Niki Efthymiou, Athanasia Zlatintsi, Petros Maragos, Nikolaos Smyrnis
<p><strong>Background: </strong>Digital phenotyping refers to the objective measurement of human behavior via devices such as smartphones or watches and constitutes a promising advancement in personalized medicine. Digital phenotypes derived from heart rate, mobility, or sleep schedule data have been used in psychiatry to either diagnose individuals with psychotic disorders or to predict relapse as a binary outcome. Machine learning models so far have achieved predictive accuracies that are significant but not large enough for clinical applications. This could hinge on broad clinical definitions, which encompass heterogeneous symptom and sign ensembles, thus hindering accurate classification. The 5-factor model for the Positive and Negative Syndrome Scale (PANSS), which entails 5 independently varying dimensions, is thought to better capture symptom variability. Using the specific definitions of this refined clinical taxonomy in combination with digital phenotypes could yield more precise results.</p><p><strong>Objective: </strong>This study aims to investigate potential links between digital phenotypes and each dimension of the 5-factor PANSS model. We also assess whether clinical, demographic, and medication variables confound said reactions.</p><p><strong>Methods: </strong>In the e-Prevention study, heart rate, accelerometer, gyroscope, and sleep schedule data were continuously collected via smartwatch for a maximum of 26 months in 38 patients with psychotic spectrum disorders. Obtaining the mean and SD for each patient-month resulted in a database consisting of more than 740 monthly data points. A linear mixed model analysis was used to ascertain connections between monthly aggregated heart rate and mobility features and the 5 symptom dimension scores of PANSS, obtained during monthly clinical interviews.</p><p><strong>Results: </strong>An increase in positive symptoms was associated with a decrease in heart interpulse variation during sleep (t570.7=-3.3, P<.001, f2=0.021), while an increase in negative symptoms was associated with a decrease in accelerometer (mean: t22.1=-3.1, P=.005, f2=0.042; SD: t20=-2.4, P=.03, f2=0.019), gyroscope (mean: t22.9=-2.8, P=.01, f2=0.016), and locomotive motor activity (t17.2=-2.4, P=.03, f2=0.016) during wakefulness. An increase in accelerometer (mean: t564.4=2.8, P=.005, f2=0.017; SD: t551.6=2.5, P=.01, f2=0.015) and gyroscope (mean: t564.5=3.2, P=.001, f2=0.022; SD: t569.2=2.8, P=.005, f2=0.017) motor activity during sleep was related to an increase in depression/anxiety symptoms as well as excitement/hostility symptoms (accelerometer SD: t469.7=3.2, P=.002, f2=0.031; gyroscope mean: t497=2.3, P=.03, f2=0.013; SD: t507.7=3.2, P=.001, f2=0.029). Excitement/hostility symptoms were further associated with an increase in normalized heart rate during sleep (t368.2=3.2, P=.001, f2=0.044) and reduced sleep:wake ratio (t562=-2.7, P=.007, f2=0.013). An increase in cognitive/disorganization symptoms was related to a
背景:数字表型是指通过智能手机或手表等设备对人类行为进行客观测量,是个性化医疗的一个有希望的进步。从心率、活动能力或睡眠时间表数据中获得的数字表型已在精神病学中用于诊断精神病患者或预测复发作为二元结果。到目前为止,机器学习模型已经取得了重要的预测准确性,但对于临床应用来说还不够大。这可能取决于广泛的临床定义,其中包括异质症状和体征集合,从而阻碍了准确的分类。Positive and Negative Syndrome Scale (PANSS)的5因素模型包含5个独立变化的维度,被认为可以更好地捕捉症状的可变性。使用这种细化临床分类学的具体定义与数字表型相结合可以产生更精确的结果。目的:本研究旨在探讨数字表型与5因子PANSS模型各维度之间的潜在联系。我们还评估临床、人口统计学和药物变量是否会混淆上述反应。方法:在e-Prevention研究中,通过智能手表连续收集38例精神谱系障碍患者的心率、加速度计、陀螺仪和睡眠时间表数据,最长时间为26个月。获得每个患者月的平均值和标准差,形成一个由740多个月数据点组成的数据库。使用线性混合模型分析来确定每月总心率和活动特征与每月临床访谈中获得的PANSS的5个症状维度得分之间的联系。结果:阳性症状的增加与睡眠期间心脏搏动变化的减少相关(t570.7=-3.3, p)结论:本研究提供了证据,证明通过连续测量数字表型评估的生物学变化可能是特定症状群的特征,而不是精神障碍的整个诊断类别。这些结果支持使用数字表型不仅作为远程患者监测的手段,而且作为精神障碍生物标志物研究的具体目标。
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引用次数: 0
A Brief, Affordable, Broad-Access Transdiagnostic Intervention (Project RE-THINK) for Adolescents: Quasi-Experimental Study. 一个简短的,负担得起的,广泛获取的青少年跨诊断干预(项目重新思考):准实验研究。
IF 5.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-11 DOI: 10.2196/65491
Christopher S Rozek, Maegan B Arney, Benjamin Kedl, Jenalee R Doom, David C Rozek
<p><strong>Background: </strong>Adolescence is a crucial developmental period characterized by elevated stress and significant mental health challenges, including depression and anxiety. With barriers, such as stigma, accessibility, and cost hindering effective treatment, leveraging school systems for mental health interventions offers a strategic advantage due to their reach and potential for scalability.</p><p><strong>Objective: </strong>This study aimed to investigate the immediate impact of "Project RE-THINK," a single-session, digital thought record intervention delivered in a school setting, on negative cognitions and overall emotional valence among adolescents.</p><p><strong>Methods: </strong>Project RE-THINK helps adolescents to identify, examine, and challenge negative cognitions to improve their mental health, as demonstrated through changes in negative cognition and overall emotional valence. Adolescents (N=1052) in grades 10-12 enrolled in high school during the 2023-2024 school year completed the digital thought record intervention activity. Using a quasi-experimental pre/post design, participants read through an example thought record and completed their own thought record, which involved identifying and describing a recent upsetting situation, answering a series of questions to challenge their negative cognition, and learning and using emotion regulation skills regarding the upsetting situation. Measures of pre- and postintervention overall emotional valence and negative cognition were collected to determine the intervention effect on participants' mental health.</p><p><strong>Results: </strong>Descriptive statistics confirmed that smaller proportions of adolescents endorsed feeling negative emotions, such as anger, shame, anxiety, disgust, guilt, sadness, and fear, after the intervention. Paired samples t tests showed that adolescents experienced a significant reduction in their belief in their negative cognition from pre- to postintervention (t1051=27.71; P<.001; d=0.85, 95% CI 0.78-0.93), which demonstrates that the intervention helped them challenge their negative thoughts about their upsetting situation, as well as significant improvements to their overall emotional valence (t1051=-31.85; P<.001; d=-0.98, 95% CI -1.06 to -0.91), which demonstrates that the intervention helped them feel better about their upsetting situation. Findings also showed a significant correlation between change in negative cognition and change in overall emotional valence (r=0.25; P<.001), supporting our hypothesis that reducing the strength of belief in negative cognitions can help improve one's emotions. Finally, analysis of covariance (ANCOVAs) confirmed that there were no significant differences in intervention efficacy by gender, race and ethnicity, or socioeconomic status, suggesting broad intervention efficacy across adolescents from different backgrounds and experiences.</p><p><strong>Conclusions: </strong>Project RE-THINK effectively improved
背景:青春期是一个关键的发育时期,其特点是压力升高和显著的心理健康挑战,包括抑郁和焦虑。由于污名、可及性和成本等障碍阻碍了有效治疗,利用学校系统进行精神卫生干预具有战略优势,因为它们的覆盖范围和可扩展性潜力。目的:本研究旨在探讨“重新思考项目”(Project RE-THINK)对青少年负面认知和整体情绪效价的直接影响。方法:rethink项目通过改变青少年的消极认知和整体情绪效价,帮助青少年识别、检查和挑战消极认知,从而改善他们的心理健康。2023-2024学年注册的10-12年级青少年(N=1052)完成了数字思想记录干预活动。采用准实验前/后设计,参与者通读一份示例思想记录,并完成自己的思想记录,包括识别和描述最近的令人沮丧的情况,回答一系列问题以挑战他们的消极认知,学习和使用与令人沮丧的情况有关的情绪调节技巧。收集干预前后总体情绪效价和负性认知的测量值,以确定干预对参与者心理健康的影响。结果:描述性统计数据证实,在干预后,较小比例的青少年认同感受到负面情绪,如愤怒、羞耻、焦虑、厌恶、内疚、悲伤和恐惧。配对样本t检验显示,从干预前到干预后,青少年对消极认知的信念显著降低(t1051=27.71)。结论:RE-THINK项目有效地改善了青少年的认知和情感结果,表明其在学校环境中具有可扩展、低成本的干预潜力。未来的研究应该探索这种干预措施的纵向影响和可能整合到正规学校课程中,以帮助青少年学习有效的情绪和应对技能,并帮助保护和维持青少年的心理健康。
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引用次数: 0
Correction: Personalization Strategies for Increasing Engagement With Digital Mental Health Resources: Sequential Multiple Assignment Randomized Trial. 更正:个性化策略增加对数字心理健康资源的参与:顺序多任务随机试验。
IF 5.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-11 DOI: 10.2196/88599
Julien Rouvere, Isabell R Griffith Fillipo, Meghan Romanelli, Ashish Sharma, Brittany A Mosser, Theresa Nguyen, Kevin Rushton, John Marion, Tim Althoff, Michael D Pullmann
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引用次数: 0
Evaluating Generative AI Psychotherapy Chatbots Used by Youth: Cross-Sectional Study. 评估青少年使用的生成式AI心理治疗聊天机器人:横断面研究。
IF 5.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-10 DOI: 10.2196/79838
Kunmi Sobowale, Daniel Kevin Humphrey, Sophia Yingruo Zhao

Background: Many youth rely on direct-to-consumer generative artificial intelligence (GenAI) chatbots for mental health support, yet the quality of the psychotherapeutic capabilities of these chatbots is understudied.

Objective: This study aimed to comprehensively evaluate and compare the quality of widely used GenAI chatbots with psychotherapeutic capabilities using the Conversational Agent for Psychotherapy Evaluation II (CAPE-II) framework.

Methods: In this cross-sectional study, trained raters used the CAPE-II framework to rate the quality of 5 chatbots from GenAI platforms widely used by youth. Trained raters role-played as youth using personas of youth with mental health challenges to prompt chatbots, facilitating conversations. Chatbot responses were generated from August to October 2024. The primary outcomes were rated scores in 9 sections. The proportion of high-quality ratings (binary rating of 1) across each section was compared between chatbots using Bonferroni-corrected chi-square tests.

Results: While GenAI chatbots were found to be accessible (104/120 high-quality ratings, 86.7%) and avoid harmful statements and misinformation (71/80, 89%), they performed poorly in their therapeutic approach (14/45, 31%) and their ability to monitor and assess risk (31/80, 39%). Privacy policies were difficult to understand, and information on chatbot model training and knowledge was unavailable, resulting in low scores. Bonferroni-corrected chi-square tests showed statistically significant differences in chatbot quality in the background, therapeutic approach, and monitoring and risk evaluation sections. Qualitatively, raters perceived most chatbots as having strong conversational abilities but found them plagued by various issues, including fabricated content and poor handling of crisis situations.

Conclusions: Direct-to-consumer GenAI chatbots are unsafe for the millions of youth who use them. While they demonstrate strengths in accessibility and conversational capabilities, they pose unacceptable risks through improper crisis handling and a lack of transparency regarding privacy and model training. Immediate reforms, including the use of standardized audits of quality, such as the CAPE-II framework, are needed. These findings provide actionable targets for platforms, regulators, and policymakers to protect youth seeking mental health support.

背景:许多年轻人依赖直接面向消费者的生成人工智能(GenAI)聊天机器人来获得心理健康支持,但这些聊天机器人的心理治疗能力的质量尚未得到充分研究。目的:本研究旨在利用心理治疗会话代理评估II (CAPE-II)框架,全面评估和比较广泛使用的具有心理治疗能力的GenAI聊天机器人的质量。方法:在这项横断面研究中,训练有素的评分者使用CAPE-II框架对来自年轻人广泛使用的GenAI平台的5个聊天机器人的质量进行评分。训练有素的评分者扮演年轻人,使用有心理健康挑战的年轻人的角色来提示聊天机器人,促进对话。聊天机器人的响应产生于2024年8月至10月。主要结果为9个部分的评分。使用bonferroni校正卡方检验比较聊天机器人在每个部分的高质量评分(二元评分为1)的比例。结果:虽然GenAI聊天机器人被发现是可访问的(104/120高质量评分,86.7%),避免有害言论和错误信息(71/ 80,89%),但它们在治疗方法(14/ 45,31%)和监测和评估风险的能力(31/ 80,39%)方面表现不佳。隐私政策难以理解,聊天机器人模型训练和知识信息不可用,导致得分较低。bonferroni校正卡方检验显示,在背景、治疗方法、监测和风险评估部分,聊天机器人的质量存在统计学上的显著差异。从质量上讲,评分者认为大多数聊天机器人具有很强的会话能力,但发现它们存在各种问题,包括捏造内容和对危机情况的处理不力。结论:直接面向消费者的GenAI聊天机器人对数百万使用它们的年轻人来说是不安全的。虽然它们在可访问性和会话能力方面表现出优势,但由于危机处理不当以及在隐私和模型培训方面缺乏透明度,它们构成了不可接受的风险。需要立即进行改革,包括使用标准化的质量审计,例如CAPE-II框架。这些发现为平台、监管机构和政策制定者提供了可操作的目标,以保护寻求心理健康支持的青少年。
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引用次数: 0
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Jmir Mental Health
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