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Web-Based Forums for People Experiencing Substance Use or Gambling Disorders: Scoping Review. 针对药物使用或赌博障碍患者的网络论坛:范围审查。
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-06-17 DOI: 10.2196/49010
Annette Peart, Freya Horn, Rachel Petukhova, Anthony Barnett, Dan I Lubman

Background: For people experiencing substance use or gambling disorders, web-based peer-supported forums are a space where they can share their experiences, gather around a collective goal, and find mutual support. Web-based peer support can help to overcome barriers to attending face-to-face meetings by enabling people experiencing addiction to seek support beyond their physical location and with the benefit of anonymity if desired. Understanding who participates in web-based peer-supported forums (and how), and the principles underpinning forums, can also assist those interested in designing or implementing similar platforms.

Objective: This study aims to review the literature on how people experiencing substance use or gambling disorders, and their family, friends, and supporters, use and participate in web-based peer-supported forums. Specifically, we asked the following research questions: (1) What are the characteristics of people who use web-based peer-supported substance use or gambling-focused forums? (2) How do people participate in web-based peer-supported forums? (3) What are the key principles reportedly underpinning the web-based peer-supported forums? (4) What are the reported outcomes of web-based peer-supported forums?

Methods: Inclusion criteria for our scoping review were peer-reviewed primary studies reporting on web-based addiction forums for adults and available in English. A primary search of 10 databases occurred in June 2021, with 2 subsequent citation searches of included studies in September 2022 and February 2024.

Results: Of the 14 included studies, the majority of web-based peer-supported forums reported were aimed specifically for, or largely used by, people experiencing alcohol problems. Results from the 9 studies that did report demographic data suggest forum users were typically women, aged between 40 years and early 50 years. Participation in web-based peer-supported forums was reported quantitatively and qualitatively. The forums reportedly were underpinned by a range of key principles, mostly mutual help approaches and recovery identity formation. Only 3 included studies reported on outcomes for forum users.

Conclusions: Web-based peer-supported forums are used by people experiencing addiction in a number of ways, to share information and experiences, and give and receive support. Seeking web-based support offers an alternative approach to traditional face-to-face support options, and may reduce some barriers to engaging in peer support.

背景:对于患有药物使用障碍或赌博障碍的人来说,基于网络的同伴互助论坛是一个可以分享经验、围绕集体目标聚集在一起并寻求相互支持的空间。基于网络的同伴支持有助于克服参加面对面会议的障碍,让有成瘾经历的人能够在其所在地以外的地方寻求支持,如果需要的话,还可以匿名。了解谁参与了基于网络的同伴互助论坛(以及如何参与),以及论坛的基本原则,也有助于那些有兴趣设计或实施类似平台的人:本研究旨在回顾有关药物使用或赌博障碍患者及其家人、朋友和支持者如何使用和参与网络同伴支持论坛的文献。具体来说,我们提出了以下研究问题:(1) 使用基于网络的同伴支持型药物使用或赌博论坛的人有哪些特征?(2) 人们如何参与基于网络的同伴互助论坛?(3) 据报道,网络同伴互助论坛的主要原则是什么?(4) 据报道,网络同伴互助论坛取得了哪些成果?范围界定综述的纳入标准是:经同行评审的、以英语撰写的、关于成人网络成瘾论坛的主要研究报告。我们于 2021 年 6 月对 10 个数据库进行了初步检索,随后于 2022 年 9 月和 2024 年 2 月对纳入的研究进行了两次引文检索:在收录的 14 项研究中,所报道的大多数基于网络的同伴支持论坛都是专门针对酗酒者或主要由酗酒者使用的。9 项报告了人口统计学数据的研究结果表明,论坛用户通常为女性,年龄在 40 岁到 50 岁之间。对参与基于网络的同伴支持论坛的情况进行了定量和定性报告。据报道,这些论坛以一系列关键原则为基础,主要是互助方法和康复身份的形成。只有 3 项研究报告了论坛用户的成果:基于网络的同伴支持论坛被成瘾者以多种方式使用,以分享信息和经验,并给予和接受支持。寻求网络支持为传统的面对面支持提供了另一种选择,并可能减少参与同伴支持的一些障碍。
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引用次数: 0
Web-Based Therapist-Guided Mindfulness-Based Cognitive Behavioral Therapy for Body Dysmorphic Disorder: Pilot Randomized Controlled Trial. 基于网络的治疗师指导的正念认知行为疗法治疗身体畸形障碍:试点随机对照试验》。
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-06-12 DOI: 10.2196/55283
Camrie Kerry, Prabhdeep Mann, Nazanin Babaei, Joel Katz, Meysam Pirbaglou, Paul Ritvo

Background: Internet-based cognitive behavioral therapy (CBT) and stand-alone mindfulness meditation interventions are gaining empirical support for a wide variety of mental health conditions. In this study, we test the efficacy of web-based therapist-guided mindfulness-based cognitive behavioral therapy (CBT-M) for body dysmorphic disorder (BDD), a psychiatric disorder characterized by preoccupations with perceived defects in appearance.

Objective: This study aims to determine whether CBT-M for BDD delivered on the web is feasible and acceptable and whether mindfulness meditation adds to CBT treatment effects for BDD.

Methods: In this 8-week, 2-arm, parallel pilot randomized controlled trial, n=28 adults (aged between 18 and 55 years) were randomly allocated to an experimental group (web-based therapist-guided CBT-M) or a control group (web-based therapist-guided CBT). Study retention, accrual, and intervention adherence were assessed, along with self-report measures for BDD, depression, anxiety, and pain intensity taken at baseline and postintervention.

Results: This study was feasible to implement and deemed acceptable by participants. After 8 weeks, significant improvements were found on all outcome measures for both treatment groups, and large between-group effect sizes favoring CBT-M were found for BDD symptom severity (d=-0.96), depression (d=-1.06), pain severity (d=-1.12), and pain interference (d=-1.28). However, linear mixed models demonstrated no significant differences between the groups over 8 weeks.

Conclusions: The results suggest that mindfulness meditation may add to beneficial web-based CBT treatment effects for BDD. An adequately powered randomized control trial of web-based CBT-M is warranted.

Trial registration: ClinicalTrials.gov NCT05402475, http://clinicaltrials.gov/ct2/show/NCT05402475.

背景:基于网络的认知行为疗法(CBT)和独立的正念冥想干预措施在治疗各种精神疾病方面正获得越来越多的经验支持。在本研究中,我们测试了基于网络的治疗师指导的正念认知行为疗法(CBT-M)对身体畸形障碍(BDD)的疗效:本研究旨在确定在网络上进行的CBT-M治疗BDD是否可行、是否可接受,以及正念冥想是否会增加CBT治疗BDD的效果:在这项为期 8 周的双臂平行试点随机对照试验中,28 名成人(年龄在 18 岁至 55 岁之间)被随机分配到实验组(基于网络的治疗师指导的 CBT-M)或对照组(基于网络的治疗师指导的 CBT)。在基线和干预后,对研究保留率、应计率和干预坚持率进行了评估,并对 BDD、抑郁、焦虑和疼痛强度进行了自我报告测量:这项研究的实施是可行的,参与者也认为可以接受。8 周后,两个治疗组的所有结果指标均有明显改善,在 BDD 症状严重程度(d=-0.96)、抑郁(d=-1.06)、疼痛严重程度(d=-1.12)和疼痛干扰(d=-1.28)方面,CBT-M 的组间效应显著。然而,线性混合模型显示,8周内各组间无显著差异:结果表明,正念冥想可能会增加基于网络的 CBT 治疗对 BDD 的有益效果。有必要对基于网络的 CBT-M 进行充分的随机对照试验:试验注册:ClinicalTrials.gov NCT05402475,http://clinicaltrials.gov/ct2/show/NCT05402475。
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引用次数: 0
Considering the Role of Human Empathy in AI-Driven Therapy. 考虑人类移情在人工智能驱动的治疗中的作用。
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-06-11 DOI: 10.2196/56529
Matan Rubin, Hadar Arnon, Jonathan D Huppert, Anat Perry

Recent breakthroughs in artificial intelligence (AI) language models have elevated the vision of using conversational AI support for mental health, with a growing body of literature indicating varying degrees of efficacy. In this paper, we ask when, in therapy, it will be easier to replace humans and, conversely, in what instances, human connection will still be more valued. We suggest that empathy lies at the heart of the answer to this question. First, we define different aspects of empathy and outline the potential empathic capabilities of humans versus AI. Next, we consider what determines when these aspects are needed most in therapy, both from the perspective of therapeutic methodology and from the perspective of patient objectives. Ultimately, our goal is to prompt further investigation and dialogue, urging both practitioners and scholars engaged in AI-mediated therapy to keep these questions and considerations in mind when investigating AI implementation in mental health.

人工智能(AI)语言模型的最新突破提升了使用人工智能对话支持心理健康的愿景,越来越多的文献显示了不同程度的疗效。在本文中,我们要问的是,在治疗过程中,什么时候更容易取代人类,反之,在什么情况下,人与人之间的联系仍然更有价值。我们认为,移情是这个问题的核心答案。首先,我们定义了移情的不同方面,并概述了人类与人工智能的潜在移情能力。接下来,我们将从治疗方法论的角度和患者目标的角度,考虑是什么决定了治疗中何时最需要这些方面。最终,我们的目标是促进进一步的研究和对话,敦促从事人工智能中介治疗的从业者和学者在研究人工智能在心理健康领域的应用时,牢记这些问题和考虑因素。
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引用次数: 0
Development of Recommendations for the Digital Sharing of Notes With Adolescents in Mental Health Care: Delphi Study. 心理健康护理中与青少年数字共享笔记的建议制定:德尔菲研究。
IF 5.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-06-06 DOI: 10.2196/57965
Martine Stecher Nielsen, Aslak Steinsbekk, Torunn Hatlen Nøst

Background: In many countries, health care professionals are legally obliged to share information from electronic health records with patients. However, concerns have been raised regarding the sharing of notes with adolescents in mental health care, and health care professionals have called for recommendations to guide this practice.

Objective: The aim was to reach a consensus among authors of scientific papers on recommendations for health care professionals' digital sharing of notes with adolescents in mental health care and to investigate whether staff at child and adolescent specialist mental health care clinics agreed with the recommendations.

Methods: A Delphi study was conducted with authors of scientific papers to reach a consensus on recommendations. The process of making the recommendations involved three steps. First, scientific papers meeting the eligibility criteria were identified through a PubMed search where the references were screened. Second, the results from the included papers were coded and transformed into recommendations in an iterative process. Third, the authors of the included papers were asked to provide feedback and consider their agreement with each of the suggested recommendations in two rounds. After the Delphi process, a cross-sectional study was conducted among staff at specialist child and adolescent mental health care clinics to assess whether they agreed with the recommendations that reached a consensus.

Results: Of the 84 invited authors, 27 responded. A consensus was reached on 17 recommendations on areas related to digital sharing of notes with adolescents in mental health care. The recommendations considered how to introduce digital access to notes, write notes, and support health care professionals, and when to withhold notes. Of the 41 staff members at child and adolescent specialist mental health care clinics, 60% or more agreed with the 17 recommendations. No consensus was reached regarding the age at which adolescents should receive digital access to their notes and the timing of digitally sharing notes with parents.

Conclusions: A total of 17 recommendations related to key aspects of health care professionals' digital sharing of notes with adolescents in mental health care achieved consensus. Health care professionals can use these recommendations to guide their practice of sharing notes with adolescents in mental health care. However, the effects and experiences of following these recommendations should be tested in clinical practice.

背景:在许多国家,医护人员有法律义务与患者共享电子健康记录中的信息。然而,人们对与青少年共享精神健康护理笔记的问题表示担忧,医护人员呼吁提出建议来指导这种做法:目的:在科学论文作者之间就医护人员与青少年共享心理健康护理笔记的建议达成共识,并调查儿童和青少年心理健康护理专科诊所的员工是否同意这些建议:与科学论文的作者进行了德尔菲研究,以就建议达成共识。提出建议的过程包括三个步骤。首先,通过 PubMed 搜索确定符合资格标准的科学论文,并筛选参考文献。其次,对收录论文的结果进行编码,并在反复过程中将其转化为建议。第三,要求收录论文的作者提供反馈意见,并分两轮考虑他们是否同意所提出的每项建议。德尔菲过程结束后,对儿童和青少年心理健康专科诊所的工作人员进行了一项横断面研究,以评估他们是否同意达成共识的建议:结果:在 84 位受邀作者中,有 27 位做出了回应。结果:在 84 位受邀作者中,有 27 位作者做出了回应,就 17 项建议达成了共识,这些建议涉及与青少年心理健康护理中的数字笔记共享相关的领域。这些建议考虑了如何采用数字方式获取笔记、撰写笔记、为医护人员提供支持以及何时不提供笔记等问题。在儿童和青少年心理健康专科诊所的 41 名工作人员中,60% 或更多的人同意 17 项建议。对于青少年应在多大年龄段才能以数字方式获取笔记以及与父母以数字方式共享笔记的时间,尚未达成共识:共有 17 项建议涉及医护人员在心理健康护理中与青少年数字化共享笔记的关键方面,这些建议已达成共识。医护人员可以利用这些建议来指导他们与青少年分享心理健康笔记的实践。不过,遵循这些建议的效果和经验还需要在临床实践中进行检验。
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引用次数: 0
Correction: Digital Phenotypes for Early Detection of Internet Gaming Disorder in Adolescent Students: Explorative Data-Driven Study. 更正:用于早期发现青少年学生网络游戏障碍的数字表型:数据驱动的探索性研究。
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-06-06 DOI: 10.2196/60568
Kwangsu Cho, Minah Kim, Youngeun Cho, Ji-Won Hur, Do Hyung Kim, Seonghyeon Park, Sunghyun Park, Moonyoung Jang, Chang-Gun Lee, Jun Soo Kwon

[This corrects the article DOI: 10.2196/50259.].

[此处更正了文章 DOI:10.2196/50259]。
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引用次数: 0
Characterizing Longitudinal Patterns in Cognition, Mood, And Activity in Depression With 6-Week High-Frequency Wearable Assessment: Observational Study. 通过为期 6 周的高频可穿戴设备评估确定抑郁症患者认知、情绪和活动的纵向模式:观察研究。
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-31 DOI: 10.2196/46895
Francesca Cormack, Maggie McCue, Caroline Skirrow, Nathan Cashdollar, Nick Taptiklis, Tempest van Schaik, Ben Fehnert, James King, Lambros Chrones, Sara Sarkey, Jasmin Kroll, Jennifer H Barnett

Background: Cognitive symptoms are an underrecognized aspect of depression that are often untreated. High-frequency cognitive assessment holds promise for improving disease and treatment monitoring. Although we have previously found it feasible to remotely assess cognition and mood in this capacity, further work is needed to ascertain the optimal methodology to implement and synthesize these techniques.

Objective: The objective of this study was to examine (1) longitudinal changes in mood, cognition, activity levels, and heart rate over 6 weeks; (2) diurnal and weekday-related changes; and (3) co-occurrence of fluctuations between mood, cognitive function, and activity.

Methods: A total of 30 adults with current mild-moderate depression stabilized on antidepressant monotherapy responded to testing delivered through an Apple Watch (Apple Inc) for 6 weeks. Outcome measures included cognitive function, assessed with 3 brief n-back tasks daily; self-reported depressed mood, assessed once daily; daily total step count; and average heart rate. Change over a 6-week duration, diurnal and day-of-week variations, and covariation between outcome measures were examined using nonlinear and multilevel models.

Results: Participants showed initial improvement in the Cognition Kit N-Back performance, followed by a learning plateau. Performance reached 90% of individual learning levels on average 10 days after study onset. N-back performance was typically better earlier and later in the day, and step counts were lower at the beginning and end of each week. Higher step counts overall were associated with faster n-back learning, and an increased daily step count was associated with better mood on the same (P<.001) and following day (P=.02). Daily n-back performance covaried with self-reported mood after participants reached their learning plateau (P=.01).

Conclusions: The current results support the feasibility and sensitivity of high-frequency cognitive assessments for disease and treatment monitoring in patients with depression. Methods to model the individual plateau in task learning can be used as a sensitive approach to better characterize changes in behavior and improve the clinical relevance of cognitive data. Wearable technology allows assessment of activity levels, which may influence both cognition and mood.

背景:认知症状是抑郁症的一个未被充分认识的方面,往往得不到治疗。高频认知评估有望改善疾病和治疗监测。虽然我们之前已经发现远程评估认知和情绪是可行的,但还需要进一步的工作来确定实施和综合这些技术的最佳方法:本研究的目的是检查:(1)6 周内情绪、认知、活动水平和心率的纵向变化;(2)与昼夜和工作日相关的变化;以及(3)情绪、认知功能和活动之间的共同波动:共有 30 名轻度-中度抑郁症患者接受了为期 6 周的 Apple Watch(苹果公司)测试。结果测量包括认知功能(每天通过 3 项简短的 N-back 任务进行评估)、自我报告的抑郁情绪(每天评估一次)、每日总步数和平均心率。我们使用非线性和多层次模型研究了 6 周内的变化、昼夜变化和周日变化以及结果测量之间的协变关系:结果:参与者的认知工具包N-Back成绩有了初步提高,但随后出现了学习停滞。平均而言,学习成绩在研究开始 10 天后达到了个人学习水平的 90%。N-Back成绩通常在一天的早些时候和晚些时候较好,步数在每周开始和结束时较低。总的来说,更高的步数与更快的 N-back 学习有关,而每天步数的增加与更好的情绪有关:目前的研究结果表明,高频认知评估对抑郁症患者的疾病和治疗监测具有可行性和敏感性。任务学习中的个体高原建模方法可作为一种灵敏的方法,更好地描述行为变化并提高认知数据的临床相关性。可穿戴技术可以评估活动水平,而活动水平可能会影响认知和情绪。
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引用次数: 0
Tablet-Based Cognitive and Eye Movement Measures as Accessible Tools for Schizophrenia Assessment: Multisite Usability Study. 基于平板电脑的认知和眼动测量作为精神分裂症评估的无障碍工具:多站点可用性研究
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-30 DOI: 10.2196/56668
Kentaro Morita, Kenichiro Miura, Atsuhito Toyomaki, Manabu Makinodan, Kazutaka Ohi, Naoki Hashimoto, Yuka Yasuda, Takako Mitsudo, Fumihiro Higuchi, Shusuke Numata, Akiko Yamada, Yohei Aoki, Hiromitsu Honda, Ryo Mizui, Masato Honda, Daisuke Fujikane, Junya Matsumoto, Naomi Hasegawa, Satsuki Ito, Hisashi Akiyama, Toshiaki Onitsuka, Yoshihiro Satomura, Kiyoto Kasai, Ryota Hashimoto

Background: Schizophrenia is a complex mental disorder characterized by significant cognitive and neurobiological alterations. Impairments in cognitive function and eye movement have been known to be promising biomarkers for schizophrenia. However, cognitive assessment methods require specialized expertise. To date, data on simplified measurement tools for assessing both cognitive function and eye movement in patients with schizophrenia are lacking.

Objective: This study aims to assess the efficacy of a novel tablet-based platform combining cognitive and eye movement measures for classifying schizophrenia.

Methods: Forty-four patients with schizophrenia, 67 healthy controls, and 41 patients with other psychiatric diagnoses participated in this study from 10 sites across Japan. A free-viewing eye movement task and 2 cognitive assessment tools (Codebreaker task from the THINC-integrated tool and the CognitiveFunctionTest app) were used for conducting assessments in a 12.9-inch iPad Pro. We performed comparative group and logistic regression analyses for evaluating the diagnostic efficacy of the 3 measures of interest.

Results: Cognitive and eye movement measures differed significantly between patients with schizophrenia and healthy controls (all 3 measures; P<.001). The Codebreaker task showed the highest classification effectiveness in distinguishing schizophrenia with an area under the receiver operating characteristic curve of 0.90. Combining cognitive and eye movement measures further improved accuracy with a maximum area under the receiver operating characteristic curve of 0.94. Cognitive measures were more effective in differentiating patients with schizophrenia from healthy controls, whereas eye movement measures better differentiated schizophrenia from other psychiatric conditions.

Conclusions: This multisite study demonstrates the feasibility and effectiveness of a tablet-based app for assessing cognitive functioning and eye movements in patients with schizophrenia. Our results suggest the potential of tablet-based assessments of cognitive function and eye movement as simple and accessible evaluation tools, which may be useful for future clinical implementation.

背景:精神分裂症是一种复杂的精神疾病,其特点是认知和神经生物学发生重大改变。众所周知,认知功能和眼球运动的损害是精神分裂症有希望的生物标志物。然而,认知评估方法需要专业知识。迄今为止,还缺乏用于评估精神分裂症患者认知功能和眼球运动的简化测量工具的数据:本研究旨在评估一种基于平板电脑的新型平台的疗效,该平台结合了认知和眼动测量方法,可对精神分裂症进行分类:44名精神分裂症患者、67名健康对照者和41名患有其他精神疾病的患者参加了这项研究,他们来自日本全国10个地方。在 12.9 英寸的 iPad Pro 中使用了自由视线眼球运动任务和两种认知评估工具(THINC 集成工具中的代码破解任务和 CognitiveFunctionTest 应用程序)进行评估。我们进行了分组比较分析和逻辑回归分析,以评估 3 种相关测量方法的诊断效果:结果:精神分裂症患者和健康对照组的认知和眼球运动测量结果存在显著差异(所有 3 项测量结果;PC):这项多站点研究证明了基于平板电脑的应用程序评估精神分裂症患者认知功能和眼球运动的可行性和有效性。我们的研究结果表明,基于平板电脑的认知功能和眼球运动评估很有可能成为简单易用的评估工具,这对今后的临床应用很有帮助。
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引用次数: 0
Cost-Effectiveness of Digital Mental Health Versus Usual Care During Humanitarian Crises in Lebanon: Pragmatic Randomized Trial 黎巴嫩人道主义危机期间数字心理健康与常规护理的成本效益:实用随机试验
IF 5.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-29 DOI: 10.2196/55544
Racha Abi Hana, Jinane Abi Ramia, Sebastian Burchert, Kenneth Carswell, Pim Cuijpers, Eva Heim, Christine Knaevelsrud, Philip Noun, Marit Sijbrandij, Mark van Ommeren, Edith van’t Hof, Ben Wijnen, Edwina Zoghbi, Rabih El Chammay, Filip Smit
<strong>Background:</strong> There is evidence from meta-analyses and systematic reviews that digital mental health interventions for depression, anxiety, and stress-related disorders tend to be cost-effective. However, no such evidence exists for guided digital mental health care in low and middle-income countries (LMICs) facing humanitarian crises, where the needs are highest. Step-by-Step (SbS), a digital mental health intervention for depression, anxiety, and stress-related disorders, proved to be effective for Lebanese citizens and war-affected Syrians residing in Lebanon. Assessing the cost-effectiveness of SbS is crucial because Lebanon’s overstretched health care system must prioritize cost-effective treatment options in the face of continuing humanitarian and economic crises. <strong>Objective:</strong> This study aims to assess the cost-effectiveness of SbS in a randomized comparison with enhanced usual care (EUC). <strong>Methods:</strong> The cost-effectiveness analysis was conducted alongside a pragmatic randomized controlled trial in 2 parallel groups comparing SbS (n=614) with EUC (n=635). The primary outcome was cost (in US $ for the reference year 2019) per treatment response of depressive symptoms, defined as >50% reduction of depressive symptoms measured using the Patient Health Questionnaire (PHQ). The secondary outcome was cost per remission of depressive symptoms, defined as a PHQ score <5 at last follow-up (5 months post baseline). The evaluation was conducted first from the health care perspective then from the societal perspective. <strong>Results:</strong> Taking the health care perspective, SbS had an 80% probability to be regarded as cost-effective compared with EUC when there is a willingness to pay US $220 per additional treatment response or US $840 per additional remission. Taking the wider societal perspective, SbS had a >75% probability to be cost-saving while gaining response or remission. <strong>Conclusions:</strong> To our knowledge, this study is the first cost-effectiveness analysis based on a large randomized controlled trial (n=1249) of a guided digital mental health intervention in an LMIC. From the principal findings, 2 implications flowed, from the (1) health care perspective and (2) wider societal perspective. First, our findings suggest that SbS is associated with greater health benefits, albeit for higher costs than EUC. It is up to decision makers in health care to decide if they find the balance between additional health gains and additional health care costs acceptable. Second, as seen from the wider societal perspective, there is a substantial likelihood that SbS is not costing more than EUC but is associated with cost-savings as SBS participants become more productive, thus offsetting their health care costs. This finding may suggest to policy makers that it is in the interest of both population health and the wider Lebanese economy to implement SbS on a wide scale. In brief, SbS may o
背景:荟萃分析和系统综述有证据表明,针对抑郁症、焦虑症和压力相关疾病的数字心理健康干预措施往往具有成本效益。然而,在面临人道主义危机的中低收入国家(LMICs),数字心理健康护理的指导却没有这样的证据。Step-by-Step (SbS)是一种针对抑郁、焦虑和压力相关疾病的数字心理健康干预措施,对居住在黎巴嫩的黎巴嫩公民和受战争影响的叙利亚人证明是有效的。评估 SbS 的成本效益至关重要,因为面对持续的人道主义和经济危机,黎巴嫩捉襟见肘的医疗保健系统必须优先考虑具有成本效益的治疗方案。研究目的本研究旨在通过随机比较 SbS 和增强型常规护理 (EUC) 来评估其成本效益。方法:在进行成本效益分析的同时,我们还对 SbS 和增强型常规护理进行了比较:成本效益分析与一项务实的随机对照试验同时进行,试验分为两个平行组,分别比较 SbS(614 人)和 EUC(635 人)。主要结果是抑郁症状每次治疗反应的成本(以 2019 年为基准年,单位为美元),定义为使用患者健康问卷(PHQ)测量的抑郁症状减少 50%。次要结果是抑郁症状每次缓解的成本,定义为在最后一次随访(基线后 5 个月)时 PHQ 得分达到 5 分。评估首先从医疗保健角度进行,然后从社会角度进行。评估结果从医疗保健的角度来看,如果愿意为每增加一个治疗反应支付 220 美元或每增加一个缓解支付 840 美元,那么与 EUC 相比,SbS 被视为具有成本效益的可能性为 80%。从更广泛的社会角度来看,SbS 在获得应答或缓解的同时有 75% 的可能性节省成本。结论:据我们所知,这项研究是首个基于大型随机对照试验(n=1249)的成本效益分析,该试验是在低收入国家开展的一项有指导的数字心理健康干预措施。从主要研究结果中,我们得出了两点启示:(1)从医疗保健的角度;(2)从更广泛的社会角度。首先,我们的研究结果表明,尽管SbS的成本高于EUC,但却能带来更大的健康效益。至于他们是否认为额外的健康收益和额外的医疗成本之间的平衡是可以接受的,这取决于医疗决策者。其次,从更广泛的社会角度来看,很有可能保健服务的成本并不比欧盟补偿金高,但却能节省成本,因为保健服务参与者的生产率提高了,从而抵消了他们的保健成本。这一发现可能会向政策制定者提出建议,即广泛实施 SbS 既符合人口健康的利益,也符合黎巴嫩更广泛的经济利益。简而言之,SbS 可为低收入国家和地区的人道主义紧急情况提供一种可扩展、有可能节约成本的应对措施。试验注册:ClinicalTrials.gov NCT03720769; https://clinicaltrials.gov/ct2/show/NCT03720769
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引用次数: 0
Effects of a Chatbot-Based Intervention on Stress and Health-Related Parameters in a Stressed Sample: Randomized Controlled Trial. 基于聊天机器人的干预对压力样本中压力和健康相关参数的影响:随机对照试验
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-28 DOI: 10.2196/50454
Christine Schillings, Echo Meißner, Benjamin Erb, Eileen Bendig, Dana Schultchen, Olga Pollatos

Background: Stress levels and the prevalence of mental disorders in the general population have been rising in recent years. Chatbot-based interventions represent novel and promising digital approaches to improve health-related parameters. However, there is a lack of research on chatbot-based interventions in the area of mental health.

Objective: The aim of this study was to investigate the effects of a 3-week chatbot-based intervention guided by the chatbot ELME, specifically with respect to the ability to reduce stress and improve various health-related parameters in a stressed sample.

Methods: In this multicenter two-armed randomized controlled trial, 118 individuals with medium to high stress levels were randomized to the intervention group (n=59) or the treatment-as-usual control group (n=59). The ELME chatbot guided participants of the intervention group through 3 weeks of training based on the topics stress, mindfulness, and interoception, with practical and psychoeducative elements delivered in two daily interactive intervention sessions via a smartphone (approximately 10-20 minutes each). The primary outcome (perceived stress) and secondary outcomes (mindfulness; interoception or interoceptive sensibility; subjective well-being; and emotion regulation, including the subfacets reappraisal and suppression) were assessed preintervention (T1), post intervention (T2; after 3 weeks), and at follow-up (T3; after 6 weeks). During both conditions, participants also underwent ecological momentary assessments of stress and interoceptive sensibility.

Results: There were no significant changes in perceived stress (β03=-.018, SE=.329; P=.96) and momentary stress. Mindfulness and the subfacet reappraisal significantly increased in the intervention group over time, whereas there was no change in the subfacet suppression. Well-being and momentary interoceptive sensibility increased in both groups over time.

Conclusions: To gain insight into how the intervention can be improved to achieve its full potential for stress reduction, besides a longer intervention duration, specific sample subgroups should be considered. The chatbot-based intervention seems to have the potential to improve mindfulness and emotion regulation in a stressed sample. Future chatbot-based studies and interventions in health care should be designed based on the latest findings on the efficacy of rule-based and artificial intelligence-based chatbots.

Trial registration: German Clinical Trials Register DRKS00027560; https://drks.de/search/en/trial/DRKS00027560.

International registered report identifier (irrid): RR2-doi.org/10.3389/fdgth.2023.1046202.

背景:近年来,普通人群的压力水平和精神疾病患病率不断上升。基于聊天机器人的干预措施是改善健康相关参数的新颖而有前景的数字方法。然而,在心理健康领域,基于聊天机器人的干预措施还缺乏研究:本研究旨在调查由聊天机器人 ELME 指导的为期 3 周的聊天机器人干预的效果,特别是在压力样本中减轻压力和改善各种健康相关参数的能力:在这项多中心双臂随机对照试验中,118 名具有中度至高度压力水平的人被随机分配到干预组(59 人)或照常治疗对照组(59 人)。ELME聊天机器人指导干预组的参与者进行为期3周的培训,培训主题包括压力、正念和内感知,每天通过智能手机进行两次互动干预(每次约10-20分钟),培训内容包括实践和心理教育。在干预前(T1)、干预后(T2;3 周后)和随访时(T3;6 周后)对主要结果(感知到的压力)和次要结果(正念、内感知或内感知敏感性、主观幸福感和情绪调节,包括重新评估和抑制两个子方面)进行了评估。在这两种情况下,参与者还接受了压力和内感知敏感性的生态瞬间评估:结果:感知压力(β03=-.018,SE=.329;P=.96)和瞬间压力均无明显变化。随着时间的推移,干预组的正念和亚方面重评显著增加,而亚方面抑制没有变化。随着时间的推移,两组的幸福感和瞬间感受性都有所提高:为了深入了解如何改进干预措施以充分发挥其减压潜力,除了延长干预时间外,还应该考虑特定的样本分组。基于聊天机器人的干预似乎有可能改善压力样本的正念和情绪调节。未来在医疗保健领域开展基于聊天机器人的研究和干预时,应根据基于规则和人工智能的聊天机器人功效的最新研究成果进行设计:德国临床试验注册中心 DRKS00027560;https://drks.de/search/en/trial/DRKS00027560.International 注册报告标识符(irrid):RR2-doi.org/10.3389/fdgth.2023.1046202.
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引用次数: 0
Examining the Effects of a Brief, Fully Self-Guided Mindfulness Ecological Momentary Intervention on Empathy and Theory-of-Mind for Generalized Anxiety Disorder: Randomized Controlled Trial. 研究简短、完全自我指导的正念生态瞬间干预对广泛性焦虑症的移情和心智理论的影响:随机对照试验》。
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-05-24 DOI: 10.2196/54412
Nur Hani Zainal, Michelle G Newman
<p><strong>Background: </strong>The utility of brief mindfulness ecological momentary interventions (EMIs) to improve empathy and theory-of-mind has been underinvestigated, particularly in generalized anxiety disorder (GAD).</p><p><strong>Objective: </strong>In this randomized controlled trial, we aimed to examine the efficacy of a 14-day, fully self-guided, mindfulness EMI on the empathy and theory-of-mind domains for GAD.</p><p><strong>Methods: </strong>Adults (aged ≥18 y) diagnosed with GAD were randomized to a mindfulness EMI (68/110, 61.8%) or self-monitoring app (42/110, 38.2%) arm. They completed the Interpersonal Reactivity Index self-report empathy measure and theory-of-mind test (Bell-Lysaker Emotion Recognition Task) at prerandomization, postintervention, and 1-month follow-up (1MFU) time points. Hierarchical linear modeling was conducted with the intent-to-treat principle to determine prerandomization to postintervention (pre-post intervention) and prerandomization to 1MFU (pre-1MFU) changes, comparing the mindfulness EMI to self-monitoring.</p><p><strong>Results: </strong>Observed effects were generally stronger from pre-1MFU than from pre-post intervention time points. From pre-post intervention time points, the mindfulness EMI was more efficacious than the self-monitoring app on fantasy (the ability to imagine being in others' shoes; between-intervention effect size: Cohen d=0.26, P=.007; within-intervention effect size: Cohen d=0.22, P=.02 for the mindfulness EMI and Cohen d=-0.16, P=.10 for the self-monitoring app). From pre-1MFU time points, the mindfulness EMI, but not the self-monitoring app, improved theory-of-mind (a window into others' thoughts and intentions through abstract, propositional knowledge about their mental states, encompassing the ability to decipher social cues) and the fantasy, personal distress (stress when witnessing others' negative experiences), and perspective-taking (understanding others' perspective) empathy domains. The effect sizes were small to moderate (Cohen d=0.15-0.36; P<.001 to P=.01) for significant between-intervention effects from pre-1MFU time points. Furthermore, the within-intervention effect sizes for these significant outcomes were stronger for the mindfulness EMI (Cohen d=0.30-0.43; P<.001 to P=.03) than the self-monitoring app (Cohen d=-0.12 to 0.21; P=.001 to P>.99) from pre-1MFU time points. No between-intervention and within-intervention effects on empathic concern (feeling affection, compassion, and care when observing others in distress, primarily attending to their emotional well-being) were observed from pre-post intervention and pre-1MFU time points.</p><p><strong>Conclusions: </strong>The brief mindfulness EMI improved specific domains of empathy (eg, fantasy, personal distress, and perspective-taking) and theory-of-mind with small to moderate effect sizes in persons with GAD. Higher-intensity, self-guided or coach-facilitated, multicomponent mindfulness EMIs targeting the op
背景:简短的正念生态瞬间干预(EMI)在改善移情和心智理论方面的效用尚未得到充分研究,尤其是在广泛性焦虑症(GAD)中:在这项随机对照试验中,我们旨在研究为期 14 天、完全自我指导的正念 EMI 对 GAD 的移情和心智理论领域的疗效:被诊断为 GAD 的成年人(年龄≥18 岁)被随机分配到正念 EMI(68/110,61.8%)或自我监控应用程序(42/110,38.2%)组。他们在随机化前、干预后和1个月随访(1MFU)时间点完成了人际反应指数自我报告移情测量和心智理论测试(Bell-Lysaker情绪识别任务)。根据意向治疗原则进行了层次线性建模,以确定从随机前到干预后(干预前-干预后)以及从随机前到1个月随访期(1个月随访期前)的变化,并将正念EMI与自我监控进行了比较:结果:从 1MFU 前的时间点观察到的效果普遍强于干预前的时间点。从干预前-干预后的时间点来看,正念 EMI 在幻想(想象自己站在他人立场的能力;干预间效应大小:干预间效应大小:Cohen d=0.26,P=.007;干预内效应大小:Cohen d=0.22,P=.007:正念 EMI 的 Cohen d=0.22,P=.02;自我监控应用程序的 Cohen d=-0.16,P=.10)。从 1MFU 前的时间点来看,正念 EMI(而非自我监控应用程序)改善了心智理论(通过对他人心理状态的抽象、命题性知识了解他人想法和意图的窗口,包括解读社交线索的能力)以及幻想、个人痛苦(目睹他人负面经历时的压力)和透视(理解他人的观点)移情领域。从 1MFU 前的时间点来看,效果大小为小到中等(Cohen d=0.15-0.36; P.99)。从干预前-干预后时间点和1MFU前时间点来看,没有观察到干预间和干预内对移情关注(当观察到他人处于困境时感到亲切、同情和关心,主要关注他们的情绪健康)的影响:简短的正念 EMI 改善了 GAD 患者移情的特定领域(如幻想、个人苦恼和透视)和心智理论,其效果大小为小到中等。要改善这类人群的移情关注领域,可能需要更高强度、自我指导或教练协助的多成分正念 EMI,以优化社会关系为目标:试验注册:ClinicalTrials.gov NCT04846777;https://clinicaltrials.gov/study/NCT04846777。
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引用次数: 0
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Jmir Mental Health
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