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Planetary Health Booms: Unpacking the Surge in Research Across the Globe Through Joint-Point Analysis 行星健康蓬勃发展:通过联合点分析解读全球研究激增。
IF 4.3 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-13 DOI: 10.1029/2024GH001028
Gladson Vaghela, Zeeshan Ali Khan, Randa Elsheikh, Abdelrahman M. Makram, Arshia Fatima, Omar Mohamed Makram, Fei He, Nguyen Tien Huy

Planetary Health (PH) is a relatively new field that studies the sciences behind the interaction between the environment, living organisms, and human health. The number of publications in this field has increased exponentially in the past few years. This study analyzed the trend of using the term “PH” in literature. We searched PubMed for all publications (APP) and those mentioning Planetary Health (APmPH) without limitations on text availability, dates, or species. The publication trend was estimated using the average annual percent change (AAPC). Joinpoint Regression Program 4.9.1.0 identified periods with statistically distinct log-linear trends in publication numbers over time. Bonferroni adjustment determined significant trend shifts. The time frame of the retrieved APP and APmPH results ranged from 2002 to 2022 with a publication boom since 2017. The most common study designs were reviews, followed by comments and editorials. The APP, APmPH, and the proportion of APmPH to APP steadily increased from 2002 to 2022, with an AAPC of 6.0% (95% CI: 4.4%–7.6%, p < 0.001), 35.7 (95% CI: 21.3%–51.9%, p < 0.001), and 28.1% (95% CI: 15.2–42.5, p < 0.001), respectively. The term “PH” is increasingly prominent in academic literature, underscoring the need for interdisciplinary efforts. Its growing usage also highlights the need for recognition in Medical Subject Headings by the National Library of Medicine.

行星健康(PH)是一个相对较新的领域,研究环境、生物体和人类健康之间相互作用背后的科学。在过去几年中,该领域的出版物数量呈指数级增长。本研究分析了文献中使用 "PH "一词的趋势。我们在 PubMed 上搜索了所有出版物(APP)以及提及 "行星健康 "的出版物(APmPH),对文本可用性、日期或物种均无限制。使用年均百分比变化(AAPC)估算出版物趋势。加入点回归程序 4.9.1.0 确定了出版物数量随时间变化呈明显对数线性趋势的时期。Bonferroni 调整确定了显著的趋势变化。检索到的 APP 和 APmPH 结果的时间范围为 2002 年至 2022 年,自 2017 年以来出现了发表热潮。最常见的研究设计是综述,其次是评论和社论。从 2002 年到 2022 年,APP、APmPH 和 APmPH 占 APP 的比例稳步上升,AAPC 为 6.0%(95% CI:4.4%-7.6%,p p p
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引用次数: 0
Satellite-Derived, Smartphone-Delivered Geospatial Cholera Risk Information for Vulnerable Populations 针对易感人群的卫星推导、智能手机提供的霍乱风险地理空间信息。
IF 4.3 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-09 DOI: 10.1029/2024GH001039
Farah Nusrat, Ali S. Akanda, Abdullah Islam, Sonia Aziz, Emily L. Pakhtigian, Kevin Boyle, Syed Manzoor Ahmed Hanifi

Cholera, an acute waterborne diarrheal disease, remains a major global health challenge. Despite being curable and preventable, it can be fatal if left untreated, especially for children. Bangladesh, a cholera-endemic country with a high disease burden, experiences two peaks annually, during the dry pre-monsoon spring and the wet post-monsoon fall seasons. An early warning system for disseminating cholera risk, which has potential to reduce the disease burden, currently does not exist in Bangladesh. Such systems can raise timely awareness and allow households in rural, riverine areas like Matlab to make behavioral adjustments with water usage and around water resources to reduce contracting and transmitting cholera. Current dissemination approaches typically target local government and public health organizations; however, the vulnerable rural populations largely remain outside the information chain. Here, we develop and evaluate the accuracy of an early warning system—CholeraMap that uses high-resolution earth observations to forecast cholera risk and disseminate geocoded risk maps directly to Matlab's population via a mobile smartphone application. Instead of relying on difficult to obtain station-based environmental and hydroclimatological data, this study offers a new opportunity to use remote sensing data sets for designing and operating a disease early warning system. CholeraMap delivers monthly, color-coded geospatial maps (1 km × 1 km spatial resolution) with household and community cholera risk information. Our results demonstrate that the satellite-derived local-scale risk model satisfactorily captured the seasonal cholera pattern for the Matlab region, and a detailed high-resolution picture of the spatial progression of at-risk areas during outbreak months.

霍乱是一种急性水传播腹泻疾病,仍然是全球健康面临的重大挑战。尽管霍乱可以治愈和预防,但如果不及时治疗,尤其是对儿童来说,可能会致命。孟加拉国是霍乱流行的国家,疾病负担沉重,每年在季风前的春季干燥季节和季风后的秋季潮湿季节出现两次发病高峰。传播霍乱风险的预警系统有可能减轻疾病负担,但孟加拉国目前还没有这种系统。这种系统可以及时提高人们的认识,让马特拉布等沿河农村地区的家庭在用水和水资源周围做出行为调整,以减少感染和传播霍乱。目前的传播方式通常以当地政府和公共卫生组织为目标,但农村弱势群体大多仍处于信息链之外。在这里,我们开发了一个预警系统--霍乱地图(CholeraMap),并对其准确性进行了评估。该系统利用高分辨率的地球观测数据预测霍乱风险,并通过移动智能手机应用程序直接向马特拉布的居民传播地理编码风险地图。这项研究提供了一个利用遥感数据集设计和运行疾病预警系统的新机会,而不是依赖难以获得的基于站点的环境和水文气候学数据。CholeraMap 每月提供彩色编码的地理空间地图(空间分辨率为 1 千米×1 千米),其中包含家庭和社区霍乱风险信息。我们的研究结果表明,由卫星衍生的地方尺度风险模型能够令人满意地捕捉到马特拉布地区的季节性霍乱模式,以及疫情爆发月份高危地区空间进展的详细高分辨率图像。
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引用次数: 0
Upstream Oil and Gas Production and Community COVID-19 Case and Mortality Rates in California, USA 美国加利福尼亚州上游石油和天然气生产与社区 COVID-19 病例和死亡率。
IF 4.3 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-07 DOI: 10.1029/2024GH001070
Helena Archer, David J. X. González, Julia Walsh, Paul English, Peggy Reynolds, W. John Boscardin, Catherine Carpenter, Rachel Morello-Frosch

Higher concentrations of ambient air pollutants, including PM2.5 and NO2, and other pollutants have been found near active oil and gas wells and may be associated with adverse COVID-19 outcomes. We assessed whether residential exposure to nearby oil and gas production was associated with higher rates of the respiratory infection COVID-19 and related mortality using a population-based ecological study in California. Using gridded population estimates, we estimated area-level exposure to annual average oil and gas production volume from active wells within 1 kilometer (km) of populated areas within census block groups from 2018 to 2020. We geocoded confirmed cases and associated deaths to assess block group case and mortality rates from COVID-19 from February 2020 to January 2021. We fit hierarchical Poisson models with individual and area covariates (e.g., age, sex, socioeconomic disadvantage), and included time and other interactions to assess additional variation (e.g., testing, reporting rates). In the first 4 months of the study period (February–May 2020), block groups in the highest tertile of oil and gas production exposure had 34% higher case rates (IRR: 1.34 95% CI: 1.20, 1.49) and 55% higher mortality rates (MRR: 1.52 95%: CI: 1.14, 2.03) than those with no estimated production, after accounting for area-level covariates. Over the entire study period, we observed moderately higher mortality rates in the highest group (MRR: 1.16 95%: CI: 1.01, 1.33) and null associations for case rates.

在活跃的油气井附近发现了较高浓度的环境空气污染物(包括 PM2.5、二氧化氮)和其他污染物,这可能与 COVID-19 的不良后果有关。我们通过在加利福尼亚州进行的一项基于人口的生态研究,评估了居民接触附近的石油和天然气生产是否与较高的呼吸道感染 COVID-19 感染率及相关死亡率有关。利用网格化人口估计值,我们估算了从 2018 年到 2020 年人口普查区块组内人口居住区 1 公里(km)范围内活跃油井的年均石油和天然气生产量的区域级暴露。我们对确诊病例和相关死亡病例进行了地理编码,以评估 2020 年 2 月至 2021 年 1 月期间 COVID-19 的区块组病例率和死亡率。我们利用个人和地区协变量(如年龄、性别、社会经济劣势)拟合了分层泊松模型,并纳入了时间和其他交互作用,以评估额外的变异(如检测、报告率)。在研究期的前 4 个月(2020 年 2 月至 5 月),在考虑地区级协变量后,与没有估计产量的区块组相比,石油和天然气生产暴露最高三分位数的区块组的病例率高 34% (IRR:1.34 95% CI:1.20, 1.49),死亡率高 55%(MRR:1.52 95% CI:1.14, 2.03)。在整个研究期间,我们观察到最高产量组的死亡率略高(MRR:1.16 95%:CI:1.01, 1.33),而病例率的相关性为零。
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引用次数: 0
Association of Long-Term Exposure to PM2.5 Constituents and Green Space With Arthritis and Rheumatoid Arthritis 长期暴露于 PM2.5 成分和绿地与关节炎和类风湿性关节炎的关系。
IF 4.3 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-06 DOI: 10.1029/2024GH001132
Yi-Sheng He, Yi-Qing Xu, Fan Cao, Zhao-Xing Gao, Man Ge, Tian He, Peng Zhang, Chan-Na Zhao, Peng Wang, Zhiwei Xu, Hai-Feng Pan

There is limited evidence regarding the effects of long-term exposure to PM2.5 constituents on the risk of arthritis and rheumatoid arthritis, and the interaction between PM2.5 and green space remains unclear. This study examined the relationship between long-term exposure to PM2.5 constituents and the risk of arthritis and rheumatoid arthritis, with the exposure period extending from recruitment until self-reported outcomes, death, loss to follow-up, or end of follow-up. Additionally, the study assessed whether there was an interactive effect between PM2.5 and green space on these risks. We gathered cohort data on 18,649 individuals aged ≥45 years. We applied generalized linear mixed-effects models to estimate the effects of PM2.5 constituents, NDVI, and their interaction on arthritis and rheumatoid arthritis. The quantile g-computation and weighted quantile sum regression model were applied to estimate the combined effect of PM2.5 constituents. Our results showed that exposure to single and mixed PM2.5 constituents adversely affected arthritis and rheumatoid arthritis, and was mainly attributed to the black carbon component. We observed “U” or “J” shaped exposure-response curves for the effects of PM2.5, OM, NO3 and NH4+ exposure on the development of arthritis/rheumatoid arthritis. Additionally, the odds ratio of arthritis for per interquartile range (IQR) increase in PM2.5 was 1.209 (95% CI:1.198, 1.221), per 0.1-unit decrease in NDVI was 1.091 (95% CI:1.033, 1.151), and the interaction term was 1.005 (95% CI:1.002, 1.007). These findings flesh out the existing evidence for PM2.5 constituents, NDVI and arthritis, rheumatoid arthritis, but the underlying mechanisms still require further exploration.

关于长期暴露于PM2.5成分对关节炎和类风湿性关节炎风险的影响,目前证据有限,而PM2.5与绿地之间的相互作用仍不清楚。本研究考察了长期暴露于PM2.5成分与关节炎和类风湿性关节炎风险之间的关系,暴露期从招募开始直至自我报告结果、死亡、失去随访或随访结束。此外,该研究还评估了 PM2.5 和绿地对这些风险是否存在交互影响。我们收集了年龄≥45岁的18649人的队列数据。我们采用广义线性混合效应模型来估计 PM2.5 成分、NDVI 及其交互作用对关节炎和类风湿性关节炎的影响。采用量子 g 计算和加权量子和回归模型来估计 PM2.5 成分的综合影响。结果表明,暴露于单一和混合的PM2.5成分会对关节炎和类风湿性关节炎产生不利影响,这主要归因于黑碳成分。我们观察到 PM2.5、OM、NO3 - 和 NH4 + 暴露对关节炎/类风湿性关节炎发病的影响呈 "U "形或 "J "形暴露反应曲线。此外,PM2.5 每增加一个四分位数(IQR),患关节炎的几率为 1.209(95% CI:1.198,1.221),NDVI 每减少 0.1 个单位,患关节炎的几率为 1.091(95% CI:1.033,1.151),交互项为 1.005(95% CI:1.002,1.007)。这些发现充实了有关 PM2.5 成分、NDVI 和关节炎、类风湿性关节炎的现有证据,但其潜在机制仍需进一步探讨。
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引用次数: 0
Methods for Quantifying Source-Specific Air Pollution Exposure to Serve Epidemiology, Risk Assessment, and Environmental Justice 量化特定来源空气污染暴露的方法,以服务于流行病学、风险评估和环境正义。
IF 4.3 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-05 DOI: 10.1029/2024GH001188
Xiaorong Shan, Joan A. Casey, Jenni A. Shearston, Lucas R. F. Henneman

Identifying sources of air pollution exposure is crucial for addressing their health impacts and associated inequities. Researchers have developed modeling approaches to resolve source-specific exposure for application in exposure assessments, epidemiology, risk assessments, and environmental justice. We explore six source-specific air pollution exposure assessment approaches: Photochemical Grid Models (PGMs), Data-Driven Statistical Models, Dispersion Models, Reduced Complexity chemical transport Models (RCMs), Receptor Models, and Proximity Exposure Estimation Models. These models have been applied to estimate exposure from sources such as on-road vehicles, power plants, industrial sources, and wildfires. We categorize these models based on their approaches for assessing emissions and atmospheric processes (e.g., statistical or first principles), their exposure units (direct physical measures or indirect measures/scaled indices), and their temporal and spatial scales. While most of the studies we discuss are from the United States, the methodologies and models are applicable to other countries and regions. We recommend identifying the key physical processes that determine exposure from a given source and using a model that sufficiently accounts for these processes. For instance, PGMs use first principles parameterizations of atmospheric processes and provide source impacts exposure variability in concentration units, although approaches within PGMs for source attribution introduce uncertainties relative to the base model and are difficult to evaluate. Evaluation is important but difficult—since source-specific exposure is difficult to observe, the most direct evaluation methods involve comparisons with alternative models.

确定空气污染暴露源对于解决其健康影响和相关的不公平问题至关重要。研究人员已开发出解决特定污染源暴露问题的建模方法,并将其应用于暴露评估、流行病学、风险评估和环境正义。我们探讨了六种针对特定污染源的空气污染暴露评估方法:光化学网格模型 (PGM)、数据驱动统计模型、扩散模型、降低复杂性化学传输模型 (RCM)、受体模型和近距离暴露估计模型。这些模型已被用于估算来自道路车辆、发电厂、工业源和野火等污染源的暴露。我们根据评估排放和大气过程的方法(如统计或第一原理)、暴露单位(直接物理测量或间接测量/比例指数)以及时间和空间尺度对这些模型进行分类。虽然我们讨论的大多数研究都来自美国,但这些方法和模型也适用于其他国家和地区。我们建议确定决定特定来源暴露的关键物理过程,并使用能充分考虑这些过程的模型。例如,PGM 使用大气过程的第一原理参数化,并以浓度单位提供源影响暴露变异性,尽管 PGM 中的源归因方法相对于基础模型会带来不确定性,并且难以评估。评估很重要,但也很困难--由于特定来源的暴露难以观测,最直接的评估方法是与替代模型进行比较。
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引用次数: 0
Updated Smoke Exposure Estimate for Indonesian Peatland Fires Using a Network of Low-Cost PM2.5 Sensors and a Regional Air Quality Model 利用低成本 PM2.5 传感器网络和区域空气质量模型对印度尼西亚泥炭地火灾的最新烟雾暴露估计。
IF 4.3 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-03 DOI: 10.1029/2024GH001125
Ailish M. Graham, Dominick V. Spracklen, James B. McQuaid, Thomas E. L. Smith, Hanun Nurrahmawati, Devina Ayona, Hasyim Mulawarman, Chaidir Adam, Effie Papargyropoulou, Richard Rigby, Rory Padfield, Shofwan Choiruzzad

Indonesia accounts for more than one third of the world's tropical peatlands. Much of the peatland in Indonesia has been deforested and drained, meaning it is more susceptible to fires, especially during drought and El Niño events. Fires are most common in Riau (Sumatra) and Central Kalimantan (Borneo) and lead to poor regional air quality. Measurements of air pollutant concentrations are sparse in both regions contributing to large uncertainties in both fire emissions and air quality degradation. We deployed a network of 13 low-cost PM2.5 sensors across urban and rural locations in Central Kalimantan and measured indoor and outdoor PM2.5 concentrations during the onset of an El Niño dry season in 2023. During the dry season (September 1st to October 31st), mean outdoor PM2.5 concentrations were 136 μg m−3, with fires contributing 90 μg m−3 to concentrations. Median indoor/outdoor (I/O) ratios were 1.01 in rural areas, considerably higher than those reported during wildfires in other regions of the world (e.g., USA), indicating housing stock in the region provides little protection from outdoor PM2.5. We combined WRF-Chem simulated PM2.5 concentrations with the median fire-derived I/O ratio and questionnaire results pertaining to participants' time spent I/O to estimate 1.62 million people in Central Kalimantan were exposed to unhealthy, very unhealthy and dangerous air quality (>55.4 μg m−3) during the dry season. Our work provides new information on the exposure of people in Central Kalimantan to smoke from fires and highlights the need for action to help reduce peatland fires.

印度尼西亚的泥炭地占全球热带泥炭地的三分之一以上。印度尼西亚的大部分泥炭地都已被砍伐和排水,这意味着泥炭地更容易发生火灾,尤其是在干旱和厄尔尼诺现象期间。火灾在廖内省(苏门答腊岛)和中加里曼丹(婆罗洲)最为常见,导致地区空气质量下降。对这两个地区空气污染物浓度的测量非常稀少,导致火灾排放和空气质量恶化都存在很大的不确定性。我们在中加里曼丹的城市和农村地区部署了由 13 个低成本 PM2.5 传感器组成的网络,并在 2023 年厄尔尼诺旱季来临时测量了室内和室外的 PM2.5 浓度。旱季期间(9 月 1 日至 10 月 31 日),室外 PM2.5 平均浓度为 136 μg m-3,其中火灾造成的浓度为 90 μg m-3。农村地区的室内/室外(I/O)比率中位数为 1.01,大大高于世界其他地区(如美国)野火期间的比率,这表明该地区的住房对室外 PM2.5 的防护作用很小。我们将WRF-Chem模拟的PM2.5浓度与火灾得出的I/O比率中位数以及有关参与者I/O时间的问卷调查结果相结合,估计中加里曼丹有162万人在旱季暴露于不健康、非常不健康和危险的空气质量(>55.4 μg m-3)中。我们的工作提供了有关中加里曼丹地区居民暴露于火灾烟雾的新信息,并强调了采取行动帮助减少泥炭地火灾的必要性。
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引用次数: 0
Association Between Short-Term Exposure to Air Pollutants and Emergency Attendance for Upper Gastrointestinal Bleeding in Hong Kong: A Time-Series Study 香港人短期暴露于空气污染物与上消化道出血急诊就诊率之间的关系:一项时间序列研究。
IF 4.3 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2024-11-01 DOI: 10.1029/2024GH001086
Yun hao Li, Jing Tong Tan, Poh Hwa Ooi, Fang Jiang, Haidong Kan, Wai K. Leung

The relationship between exposure to ambient air pollutants and emergency attendance for upper gastrointestinal bleeding (UGIB) remains inconclusive. This study examines the association between short-term exposure to various ambient pollutants and the risk of UGIB emergency attendance. Data on daily UGIB emergency attendance, ambient pollutants, and meteorological conditions in Hong Kong were collected from 2017 to 2022. A time-series study using a distributed lag non-linear model to analyze the data, considering lag days. Stratified analysis was performed based on sex, seasons, and the COVID-19 pandemic period. The burden was quantified using attributable fraction (AF) and number (AN). The study included 31,577 UGIB emergency records. Exposure to high levels of PM2.5 significantly increased the risk of UGIB emergency attendance from lag day 3 (RR: 1.012) to day 6 (RR: 1.008). High NO2 exposure also posed a significant risk from lag day 0 (RR: 1.026) to day 2 (RR: 1.014), and from lag day 5 (RR: 1.013) to day 7 (RR: 1.024). However, there was no association between UGIB and high O3 levels. The attributable burden of high-concentration NO2 exposure was higher compared to those of PM2.5. Males and elderly individuals (≥65 years) faced a higher risk of UGIB emergencies, particularly during cold seasons. Our study suggests that both PM2.5 and NO2 exposure are associated with an increased risk of emergency attendance for UGIB. Ambient pollutant exposure has a stronger effect on UGIB in males and the elderly, particularly during cold seasons.

暴露于环境空气污染物与上消化道出血(UGIB)急诊就诊之间的关系仍无定论。本研究探讨了短期暴露于各种环境污染物与上消化道出血急诊就诊风险之间的关系。研究收集了2017年至2022年香港每日胃肠道出血急诊就诊人数、环境污染物和气象条件的数据。考虑到滞后天数,采用分布式滞后非线性模型对数据进行时间序列研究分析。根据性别、季节和 COVID-19 大流行期间进行了分层分析。使用可归因分数(AF)和数量(AN)对负担进行量化。研究包括 31,577 份 UGIB 急诊记录。从滞后第 3 天(RR:1.012)到第 6 天(RR:1.008),暴露于高浓度 PM2.5 会显著增加 UGIB 急诊就诊风险。从滞后第 0 天(RR:1.026)到第 2 天(RR:1.014),以及从滞后第 5 天(RR:1.013)到第 7 天(RR:1.024),暴露于高浓度 NO2 的风险也很高。然而,UGIB 与高浓度 O3 之间没有关联。与PM2.5相比,高浓度二氧化氮暴露的可归因负担更高。男性和老年人(≥65 岁)发生 UGIB 紧急状况的风险更高,尤其是在寒冷季节。我们的研究表明,PM2.5和二氧化氮暴露与尿路感染急诊就诊风险的增加有关。环境污染物暴露对男性和老年人的 UGIB 影响更大,尤其是在寒冷季节。
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引用次数: 0
A Global Meta-Analysis of the Effects of Greenspaces on COVID-19 Infection and Mortality Rates 绿地对 COVID-19 感染率和死亡率影响的全球元分析。
IF 4.3 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-10 DOI: 10.1029/2024GH001110
Bopaki Phogole, Kowiyou Yessoufou

The COVID-19 outbreak in 2020 resulted in rapidly rising infection rates with high associated mortality rates. In response, several epidemiological studies aimed to define ways in which the spread and severity of COVID-19 can be curbed. As a result, there is a steady increase in the evidence linking greenspaces and COVID-19 impact. However, the evidence of the benefits of greenspaces or greenness to human wellbeing in the context of COVID-19 is fragmented and sometimes contradictory. This calls for a meta-analysis of existing studies to clarify the matter. Here, we identified 621 studies across the world on the matter, which were then filtered down to 13 relevant studies for meta-analysis, covering Africa, Asia, Europe, and the USA. These studies were meta-analyzed, with the impacts of greenness on COVID-19 infection rate quantified using regression estimates whereas impacts on mortality rates were measured using mortality rate ratios. We found evidence of significant negative correlations between greenness and both COVID-19 infection and mortality rates. We further found that the impacts on COVID-19 infection and related mortality are moderated by year of publication, greenness metrics, sample size, health and political covariates. This clarification has far-reaching implications for policy development toward the establishment and management of green infrastructure for the benefit of human wellbeing.

2020 年爆发的 COVID-19 导致感染率迅速上升,相关死亡率也很高。为此,多项流行病学研究旨在确定遏制 COVID-19 传播和严重程度的方法。因此,将绿地与 COVID-19 的影响联系起来的证据不断增加。然而,在 COVID-19 的背景下,有关绿地或绿化对人类福祉益处的证据并不完整,有时甚至相互矛盾。这就需要对现有研究进行荟萃分析,以澄清这一问题。在此,我们在全球范围内确定了 621 项相关研究,然后筛选出 13 项相关研究进行荟萃分析,涵盖非洲、亚洲、欧洲和美国。我们对这些研究进行了荟萃分析,使用回归估计值量化了绿化对 COVID-19 感染率的影响,而使用死亡率比率衡量了对死亡率的影响。我们发现有证据表明,绿化与 COVID-19 感染率和死亡率之间存在明显的负相关。我们还发现,发表年份、绿化指标、样本大小、健康和政治协变量都会对 COVID-19 感染率和相关死亡率的影响产生调节作用。这一结论对制定政策,建立和管理绿色基础设施,造福人类福祉具有深远影响。
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引用次数: 0
The Impact of Wildfire Smoke on Asthma Control in California: A Microsimulation Approach 加州野火烟雾对哮喘控制的影响:微观模拟法
IF 4.3 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-04 DOI: 10.1029/2024GH001037
Sigal Maya, Neeta Thakur, Tarik Benmarhnia, Sheri D. Weiser, James G. Kahn

Wildfire smoke exposure leads to poorer health among those with pre-existing conditions such as asthma. Particulate matter in wildfire smoke can worsen asthma control, cause acute exacerbations, and increase health resource utilization (HRU) and costs. Research to date has been retrospective with few opportunities to project changes in underlying asthma control and HRU given exposure to wildfire smoke. Using a microsimulation of 5,000 Californians with asthma, we calculated changes in asthma control distribution, risk of exacerbation, and HRU and cost outcomes in the 16 weeks during and after a wildfire. The model was calibrated against empirical values on asthma control distribution and increased HRU after exposure to wildfire smoke. Without smoke exposure, 48% of the cohort exhibited complete or well control of asthma, and 8% required acute healthcare per cycle. Following two consecutive weeks of wildfire smoke, complete or well control of asthma fell to 27%, with an additional 4% HRU. This corresponds to total additional $601,250 in all-cause medical costs and eight fewer quality-adjusted life years over 16 weeks of model time. Our model found increased asthma health and cost burden due to wildfire smoke that were aligned with empirical evidence from a historic wildfire event. This study establishes a framework for a more nuanced understanding of asthma impacts from wildfire smoke that can help inform the development of public health policies to mitigate harm and promote resilience among asthma patients in the face of climate change.

接触野火烟雾会导致哮喘等原有疾病患者的健康状况恶化。野火烟雾中的微粒物质会使哮喘控制恶化,导致急性加重,并增加卫生资源利用率(HRU)和成本。迄今为止的研究都是回顾性的,很少有机会预测暴露于野火烟雾后潜在的哮喘控制和医疗资源利用率的变化。通过对 5000 名加利福尼亚哮喘患者进行微观模拟,我们计算了野火期间和野火后 16 周内哮喘控制分布、病情恶化风险以及 HRU 和成本结果的变化。该模型是根据哮喘控制分布的经验值和暴露于野火烟雾后增加的 HRU 进行校准的。在未暴露于烟雾的情况下,48% 的人群表现出完全或良好的哮喘控制,8% 的人群在每个周期需要急性医疗护理。连续两周的野火烟雾暴露后,哮喘完全或良好控制率降至 27%,HRU 增加了 4%。这相当于在 16 周的模型时间内,全因医疗成本增加了 601,250 美元,质量调整生命年减少了 8 年。我们的模型发现,野火烟雾增加了哮喘的健康和成本负担,这与历史性野火事件的经验证据一致。这项研究为更细致地了解野火烟雾对哮喘的影响建立了一个框架,有助于为制定公共卫生政策提供信息,以减轻危害并提高哮喘患者面对气候变化时的适应能力。
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引用次数: 0
Blowin’ in the Wind: Mapping the Dispersion of Metal(loid)s From Atacama Mining 在风中飘扬:绘制阿塔卡马采矿金属(loid)的散布图。
IF 4.3 2区 医学 Q2 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-01 DOI: 10.1029/2024GH001078
Nicolás C. Zanetta-Colombo, Carlos A. Manzano, Dagmar Brombierstäudl, Zoë L. Fleming, Eugenia M. Gayo, David A. Rubinos, Óscar Jerez, Jorge Valdés, Manuel Prieto, Marcus Nüsser

The Atacama Desert’s naturally elevated metal(loid)s pose a unique challenge for assessing the environmental impact of mining, particularly for indigenous communities residing in these areas. This study investigates how copper mining influences the dispersion of these elements in the wind-transportable fraction (<75 μm) of surface sediments across an 80 km radius. We employed a multi-pronged approach, utilizing spatial modeling to map element distributions, exponential decay analysis to quantify concentration decline with distance, regime shift modeling to identify dispersion pattern variations, and pollution assessment to evaluate impact. Our results reveal significant mining-driven increases in surface concentrations of copper (Cu), molybdenum (Mo), and arsenic (As). Notably, within the first 20 km, concentrations peaked at 1,016 mg kg⁻1 for Cu, 31 mg kg⁻1 for Mo, and a remarkable 165 mg kg⁻1 for As. Cu and Mo displayed significant dispersion, extending up to 50 km from the source. However, As exhibited the most extensive reach, traveling up to 70 km downwind, highlighting the far-reaching ecological footprint of mining operations. Mineralogical analyses corroborated these findings, identifying mining-related minerals in surface sediments far beyond the immediate mining area. Although pollution indices based on the proposed Local Geochemical Background reveal significant contamination across the study area, establishing accurate pre-industrial baseline values is essential for a more reliable assessment. This study challenges the concept of “natural pollution” by demonstrating that human activities exacerbate baseline metal(loid)s levels. Expanding monitoring protocols is imperative to comprehensively assess the combined effects of multiple emission sources, including mining and natural processes, in safeguarding environmental and human health for future generations.

阿塔卡马沙漠天然存在的高浓度金属元素对评估采矿对环境的影响构成了独特的挑战,尤其是对居住在这些地区的土著社区而言。本研究调查了铜矿开采如何影响这些元素在风中的扩散(铜为 1,钼为 31 毫克/千克,砷为 165 毫克/千克)。铜和钼的散布范围很广,从源头开始最远可达 50 千米。然而,砷的扩散范围最广,顺风可达 70 千米,突出表明了采矿作业对生态环境的深远影响。矿物学分析证实了这些发现,在地表沉积物中发现了与采矿有关的矿物,其范围远远超出了附近的采矿区。尽管基于建议的 "当地地球化学背景 "的污染指数显示整个研究区域存在严重污染,但要进行更可靠的评估,就必须确定准确的工业化前基线值。这项研究挑战了 "自然污染 "的概念,证明人类活动加剧了金属(loid)的基线水平。为了全面评估包括采矿和自然过程在内的多种排放源的综合影响,为子孙后代保护环境和人类健康,扩大监测协议势在必行。
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