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Masthead: ChemBioEng Reviews 6/2023 刊头:ChemBioEng Reviews 6/2023
IF 4.8 3区 工程技术 Q1 ENGINEERING, CHEMICAL Pub Date : 2023-12-14 DOI: 10.1002/cben.202370602
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引用次数: 0
Unlocking the Anticancer Potential of Ionic Liquids 释放离子液体的抗癌潜力
IF 4.8 3区 工程技术 Q1 ENGINEERING, CHEMICAL Pub Date : 2023-12-14 DOI: 10.1002/cben.202300051
Najihah Mohd Noor, Ts. Dr. Amal A. M. Elgharbawy, Assoc. Prof. Dr. Muhammad Moniruzzaman, Prof. Masahiro Goto

Despite advances in cancer treatment, many types of cancer still have high mortality rates, and the existing therapies can cause considerable side effects. Therefore, discovering new therapies, especially ones with fewer side effects, is desirable to improve the outcomes for cancer patients. Ionic liquids (ILs) have emerged as potential candidates for cancer treatment because of their particular physicochemical properties, which can be tailored for specific applications. In recent years, interest in exploring the potential of ILs in cancer treatment has been growing, and several studies have demonstrated the effectiveness of ILs in inhibiting cancer-cell growth. This review provides insight into the anticancer potential of ILs, exploring the diverse applications and the underlying mechanisms behind the cytotoxicity toward cancer cells of ILs. Understanding the mechanisms behind the cytotoxicity of ILs can aid in the design and optimization of IL-based cancer therapies. By focusing on specific pathways and targets, IL-based cancer therapies may be developed that offer new possibilities for treating this devastating disease.

尽管癌症治疗取得了进步,但许多类型的癌症仍然有很高的死亡率,而且现有的治疗方法可能会产生相当大的副作用。因此,发现新的治疗方法,特别是副作用更小的治疗方法,是改善癌症患者预后的理想方法。离子液体(ILs)因其特殊的物理化学性质而成为癌症治疗的潜在候选者,可以针对特定的应用进行定制。近年来,人们对探索il在癌症治疗中的潜力越来越感兴趣,一些研究已经证明了il在抑制癌细胞生长方面的有效性。本文综述了白介素的抗癌潜力,探讨了白介素的多种应用及其对癌细胞的细胞毒性作用机制。了解白细胞介素细胞毒性背后的机制有助于设计和优化基于白细胞介素的癌症治疗方法。通过专注于特定的途径和靶点,基于白介素的癌症疗法可能会被开发出来,为治疗这种毁灭性疾病提供新的可能性。
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引用次数: 0
Table of Contents: ChemBioEng Reviews 6/2023 目录:化学生物工程评论 6/2023
IF 4.8 3区 工程技术 Q1 ENGINEERING, CHEMICAL Pub Date : 2023-12-14 DOI: 10.1002/cben.202370603
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引用次数: 0
Cover Picture: ChemBioEng Reviews 6/2023 封面图片:ChemBioEng Reviews 6/2023
IF 4.8 3区 工程技术 Q1 ENGINEERING, CHEMICAL Pub Date : 2023-12-14 DOI: 10.1002/cben.202370601

Oil Refinery, Chemical & Petrochemical plant. Copyright: zorazhuang

炼油、化工;石化工厂。版权:zorazhuang
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引用次数: 0
Present and Future Generation of Secondary Batteries: A Review 当前和未来的二次电池:综述
IF 4.8 3区 工程技术 Q1 ENGINEERING, CHEMICAL Pub Date : 2023-12-05 DOI: 10.1002/cben.202200040
S. Hemavathi, Dr. Srinivas Srirama, Dr. A. S. Prakash

Major support for the future energy storage and application will benefit from lithium-ion batteries (LIBs) with high energy density and high power. LIBs are currently the most common battery type for most applications, but soon a broader range of battery types and higher energy densities will be available. In the near future, hundreds of millions of electric vehicles are expected to be on the road, and a large amount of cobalt will be depleted. Various kinds of batteries are developed today to store energy, including Li-ion, lead-acid, Ni-MH, redox flow, Na-ion, Mg-ion, Li-air, Al-ion, Li/S, NC-based batteries, Al-based batteries, metal-air batteries, solid-state batteries, etc. There are several types of battery components, such as electrodes, electrolytes, separators, etc. Cell chemistry and component diversity will continue to increase with future generations of batteries. Next-generation LIBs and sodium-ion batteries are explored for their ability to reduce active ion loss and increase energy density by pre-lithiation. To maximize the electrochemical system's performance, various scientific and technological approaches are needed to maximize the potential of battery chemistry.

具有高能量密度和高功率的锂离子电池将成为未来能源存储和应用的主要支撑。锂电池目前是大多数应用中最常见的电池类型,但很快就会出现更广泛的电池类型和更高的能量密度。在不久的将来,预计将有数亿辆电动汽车上路,大量的钴将被耗尽。目前已经开发出各种各样的储能电池,包括锂离子电池、铅酸电池、镍氢电池、氧化还原流电池、钠离子电池、镁离子电池、锂空气电池、铝离子电池、锂/S电池、nc基电池、铝基电池、金属空气电池、固态电池等。电池组件有几种类型,如电极、电解质、分离器等。随着未来几代电池的发展,电池化学和组件的多样性将继续增加。下一代锂离子电池和钠离子电池正在探索其减少活性离子损失和通过预锂化提高能量密度的能力。为了最大限度地发挥电化学系统的性能,需要各种科学技术手段来最大限度地发挥电池化学的潜力。
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引用次数: 0
Process Parameters Influence Product Yield and Kinetic Parameters in Lipase Catalysis 脂肪酶催化过程中工艺参数对产物收率和动力学参数的影响
IF 4.8 3区 工程技术 Q1 ENGINEERING, CHEMICAL Pub Date : 2023-12-04 DOI: 10.1002/cben.202300035
Abir Lal Bose, Debapriya Bhattacharjee, Dr. Debajyoti Goswami

Effects of process parameters like enzyme concentration, concentration and type of substrate, pH, temperature, speed of agitation, and pressure on lipase catalysis are reviewed. The enzyme concentration controls its interfacial presence and consequently the rate of reaction. A change in substrate concentration alters lipase kinetics. Substrate-lipase interaction varies with substrate type and pH. Water concentration and agitation affect the extent of interfacial area. Temperature impacts the rate and thermal denaturation of enzymes. Statistical optimization can solve the problem of controlling a variable's effect by other variables. Immobilization support and nonionic surfactant altered the significance of enzyme concentration. The lipase type controlled the impact of concentrations of enzyme, substrate, and water. The water content was important during lipase-catalyzed hydrolysis and esterification. The mode of agitation influenced the significance of enzyme concentration and temperature. Time had a remarkable impact during hydrolysis. Temperature, substrate type, and chain length notably controlled kinetic parameters. This work paves the way for similar studies on other enzymes.

综述了酶浓度、底物浓度和种类、pH、温度、搅拌速度和压力等工艺参数对脂肪酶催化的影响。酶的浓度控制其界面的存在,从而控制反应的速率。底物浓度的变化会改变脂肪酶动力学。底物与脂肪酶的相互作用随底物类型和ph的不同而不同。水的浓度和搅拌影响界面面积的大小。温度影响酶的速率和热变性。统计优化可以解决由其他变量控制一个变量的效果的问题。固定化载体和非离子表面活性剂改变了酶浓度的意义。脂肪酶类型控制酶、底物和水浓度的影响。在脂肪酶催化的水解和酯化过程中,水的含量是很重要的。搅拌方式对酶浓度和温度有显著影响。时间对水解有显著影响。温度、底物类型和链长明显控制动力学参数。这项工作为其他酶的类似研究铺平了道路。
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引用次数: 0
Sustainable Opportunities in the Downstream Processing of the Intracellular Biopolymer Polyhydroxyalkanoate 细胞内生物聚合物聚羟基烷酸酯下游加工的可持续发展机会
IF 4.8 3区 工程技术 Q1 ENGINEERING, CHEMICAL Pub Date : 2023-11-27 DOI: 10.1002/cben.202300040
Sohani G. Bhat, Dr. V. Thivaharan, Dr. M. S. Divyashree

Biopolymers have gained popularity as an alternative product to traditional plastics due to environmental concerns. Polyhydroxyalkanoates (PHAs), one of the most well-known forms of biopolymers, are among the many that have been discovered so far. PHA has a wide range of applications, is biodegradable and compatible with living things, but its expensive extraction and production make it difficult to compete with traditional plastics. Solvents are the most popular extraction technique but have serious economic and environmental downsides. The “green method of extraction” has become a cutting-edge remedy for addressing the shortcomings of downstream processing. However, developing the extraction technique for affordable and environmentally friendly biopolymer production is a difficult study topic. To make it easier to choose green recovery techniques for future study, this review combines the benefits and drawbacks of the numerous PHA recovery methods that are already in use. Also, advanced green downstream methods are scrutinized that undoubtedly makes PHA replace conventional plastics and reach a market globally promoting sustainability.

由于对环境的关注,生物聚合物作为传统塑料的替代产品越来越受欢迎。聚羟基烷酸酯(PHAs)是最著名的生物聚合物之一,也是迄今为止发现的众多生物聚合物之一。PHA具有广泛的应用,可生物降解,与生物兼容,但其昂贵的提取和生产使其难以与传统塑料竞争。溶剂萃取是最流行的萃取技术,但具有严重的经济和环境缺点。“绿色提取方法”已成为解决下游加工缺点的前沿补救措施。然而,开发经济、环保的生物聚合物提取技术是一个困难的研究课题。为了使未来的研究更容易选择绿色回收技术,本综述结合了许多已经使用的PHA回收方法的优点和缺点。此外,先进的绿色下游方法被仔细审查,无疑使PHA取代传统塑料,并达到全球市场促进可持续发展。
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引用次数: 0
Utilization of Response Surface Methodology in Electrocoagulation for Process Optimization and Parametric Analysis 响应面法在电凝工艺优化和参数分析中的应用
IF 4.8 3区 工程技术 Q1 ENGINEERING, CHEMICAL Pub Date : 2023-11-27 DOI: 10.1002/cben.202300031
Adnan Akhtar, Dr. Malik Shoaib Suleman, Syed Muzammil Awais Gillani, Prof. Zaheer Aslam

Electrocoagulation (EC) is a well-recognized and feasible treatment technique for wastewater treatment. The process optimization and analysis of process parameters of EC not only aid to scale up the EC process at an industrial level but also help to explore the economic and environmental considerations to achieve higher efficiency. Response surface methodology (RSM) is a prominent chemometric approach for both process optimization and evaluation of different factors for the removal of target pollutants from wastewater. This review provides a thorough examination of notable scholarly works that focus on the use of the RSM in EC for the purpose of wastewater treatment. Furthermore, the current advancements in implementing the RSM approach not only for standalone EC processes but also for the case are described where it is being practiced as a part in the integrating system for wastewater treatment.

电絮凝(EC)是一种公认可行的污水处理技术。工艺优化和工艺参数分析不仅有助于在工业水平上扩大EC工艺,而且有助于探索经济和环境方面的考虑,以实现更高的效率。响应面法(RSM)是一种重要的化学计量学方法,用于工艺优化和评价去除废水中目标污染物的不同因素。这篇综述提供了一个全面的研究,重点是在EC中使用RSM用于废水处理。此外,目前在实施RSM方法方面取得的进展不仅适用于独立的EC过程,也适用于将其作为污水处理综合系统的一部分进行实践的案例。
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引用次数: 0
Ladle Furnace Slag: Synthesis, Properties, and Applications 钢包炉渣:合成、性能及应用
IF 4.8 3区 工程技术 Q1 ENGINEERING, CHEMICAL Pub Date : 2023-11-23 DOI: 10.1002/cben.202300024
Liya Jacob

Ladle slag is a byproduct formed during the ladle refining stage of steel making. It is a dusty material that has been considered industrial waste. Technical advancements towards a sustainable industry led to the development of different applications for ladle slag. Depending on the processing methods during the steel slag production and the weathering of the slag post-production, the elemental composition of the steel slag largely varies. Owing to this, its characteristics cannot be generalized and specific applications depending on the sources are developed. It is generally used in construction materials, soil rejuvenation, and CO2 capture. This paper reviews the production process, the mineralogical and morphological properties, stabilization techniques, and the applications of ladle furnace (LF) slag. One of the prime focuses of waste remediation and sustainable industry is to find meaningful ways to turn waste into products. In this respect, a comprehensive review of the properties of LF slag and its current application will help provide a framework for the development of future sustainability goals. With increased slag usage, the ladle refining process of steelmaking can be turned into a more carbon-neutral process.

钢包渣是炼钢过程中钢包精炼阶段产生的副产物。这是一种被认为是工业废料的含尘材料。可持续工业的技术进步导致了钢包渣不同用途的发展。根据钢渣生产过程中的处理方法和生产后钢渣的风化情况,钢渣的元素组成变化很大。因此,它的特点不能一概而论,而具体的应用取决于来源的发展。它通常用于建筑材料、土壤复壮和二氧化碳捕获。本文综述了钢包炉炉渣的生产工艺、矿物学和形态特征、稳定技术及其应用。废物修复和可持续工业的主要焦点之一是找到有意义的方法将废物转化为产品。在这方面,全面审查LF渣的性质及其目前的应用将有助于为未来可持续发展目标的制定提供框架。随着炉渣用量的增加,炼钢钢包精炼过程可以变成一个更碳中和的过程。
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引用次数: 0
Phytoremediation: A Shift Towards Sustainability for Dairy Wastewater Treatment 植物修复:乳品废水处理向可持续性转变
IF 4.8 3区 工程技术 Q1 ENGINEERING, CHEMICAL Pub Date : 2023-11-10 DOI: 10.1002/cben.202300038
Sakshi Agrahari, Dr. Sushil Kumar

Dairy processing industries have emerged as the most swiftly evolving sectors with excessive wastewater generation containing proteins, fat, oils, greases (FOGs), etc. As there is rising strain on energy usage and dependence on water resources, sustainable research focuses on reduction in wastewater generation and developing value-added goods. An effective and widely explored sustainable technique for treating wastewater is phytoremediation, a plant-based process. This review aims to analyze phytoremediation as a sustainable alternative for dairy wastewater treatment. It initially briefs about dairy wastewater characteristics and treatment alternatives and discusses constructed wetlands and hydroponic system in detail with mechanism insights and influenced process parameters. Interconnected technologies with phytoremediation and their impact on contaminant transformations, nutrient reuse, and detoxification of pollutants are encompassed. Also, resource recovery and biomass utilization, feedstock enrichment along with the future prospects of integrated hydroponic systems for achieving sustainability with efficient resource recovery are featured.

乳制品加工业是发展最迅速的行业,其产生的废水中含有过量的蛋白质、脂肪、油脂(FOGs)等。由于能源使用和对水资源的依赖日益紧张,可持续研究的重点是减少废水产生量和开发增值产品。植物修复是一种以植物为基础的工艺,是一种有效且被广泛探索的可持续废水处理技术。本综述旨在分析植物修复作为乳制品废水处理的一种可持续替代方法。文章首先简要介绍了乳制品废水的特点和处理方法,然后详细讨论了构建湿地和水培系统的机理和影响工艺参数。报告还介绍了与植物修复相关的技术及其对污染物转化、养分再利用和解毒的影响。此外,还介绍了资源回收和生物质利用、原料富集以及综合水培系统的未来前景,以便通过高效的资源回收实现可持续发展。
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引用次数: 0
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ChemBioEng Reviews
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